Aging: Heart

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18 Substances Researched for Aging: Heart
NameACCKFocus
Folic Acid 110Locked
Vitamin B-6110Locked
Vitamin B12110Locked
Chokeberry24Locked
Resveratrol24Locked
Vitamin D24Locked
Naringenin 23Locked
Arginine12Locked
Coenzyme Q1012Locked
Fucoidan12Locked
Fucoxanthin 12Locked
Ginkgo biloba12Locked
Mangiferin12Locked
Melatonin12Locked
Panax Notoginseng12Locked
Sulforaphane12Locked
Formononetin11Locked
Ginsenosides11Locked

View the Evidence:
17 Abstracts with Aging: Heart Research

[+]

Adequate dietary vitamin B9 and B12 intakes are significantly associated with a better cognitive performance.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2022 ;18:537-553. Epub 2022 Mar 9. PMID: 35359912
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B12, Vitamin B-6
Diseases : Aging: Heart, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

It is concluded that the cardioprotective effect of resveratrol is due to the antioxidant effect and other antiaging effects.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:1390483. Epub 2018 May 2. PMID: 29854072
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Aging: Heart, Oxidative Stress
Pharmacological Actions : Cardioprotective
[+]

Aronia melanocarpa fruit juice reveals neuroprotective effect and improves cognitive and locomotor functions of aged rats.Jul 11, 2019

Pubmed Data : Food Chem Toxicol. 2019 Jul 12 ;132:110674. Epub 2019 Jul 12. PMID: 31306687
Article Published Date : Jul 11, 2019
Study Type : Animal Study
Additional Links
Substances : Chokeberry
Diseases : Aging: Heart
Pharmacological Actions : Neuroprotective Agents
[+]

Co-administration of resveratrol and vitamin D protects the heart against aging-induced damage.Nov 26, 2018

Pubmed Data : Aging Clin Exp Res. 2018 Nov 27. Epub 2018 Nov 27. PMID: 30484255
Article Published Date : Nov 26, 2018
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Vitamin D
Diseases : Aging: Heart
Pharmacological Actions : Antioxidants, Cardioprotective, Catalase Up-Regulation, Superoxide Dismutase Up-regulation
[+]

Fucoidan and fucoxanthin in combination can potentially reduce cardiac hypertrophy, cardiac fibrosis, ROS level,Jan 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Jan 21 ;17(1). Epub 2019 Jan 21. PMID: 30669571
Article Published Date : Jan 20, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoidan, Fucoxanthin
Diseases : Aging: Heart, Cardiac Hypertrophy, Myocardial Fibrosis
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Mangiferin ameliorates cardiac fibrosis in D-galactose-induced aging.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2021 Mar 1 ;25(2):131-137. PMID: 33602883
Article Published Date : Feb 28, 2021
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Aging: Heart, Myocardial Fibrosis
Pharmacological Actions : Anti-Fibrotic, Cardioprotective
[+]

Melatonin/Nrf2/NLRP3 connection in mouse heart mitochondria during aging.Nov 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Nov 27 ;9(12). Epub 2020 Nov 27. PMID: 33260800
Article Published Date : Nov 26, 2020
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aging: Heart
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Nrf2 activation
[+]

Myocardium-protective effects of Ginkgo biloba extract (EGb 761) in old rats against acute isobaric hypoxia. An electron microscopic morphometric study. I. Protection of cardiomyocytes.Dec 31, 1995

Pubmed Data : Exp Toxicol Pathol. 1996 Jan ;48(1):33-9. PMID: 8919269
Article Published Date : Dec 31, 1995
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Aging: Heart
Pharmacological Actions : Antioxidants, Cardioprotective
Additional Keywords : Plant Extracts
[+]

Panax notoginseng saponins attenuate cardiomyocyte apoptosis through mitochondrial pathway in natural aging rats.Jan 31, 2018

Pubmed Data : Phytother Res. 2018 Feb ;32(2):243-250. Epub 2017 Nov 12. PMID: 29130614
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Aging: Heart
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective
Additional Keywords : Aging: Heart, Anti-Apoptotic, Antioxidants, Cardioprotective, Panax Notoginseng
[+]

Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling.Oct 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Cell. 2020 Oct 17:e13261. Epub 2020 Oct 17. PMID: 33067900
Article Published Date : Oct 16, 2020
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Aging: Heart, Cardiovascular Diseases
Pharmacological Actions : Antioxidants, Cardioprotective, Nrf2 activation
[+]

The use of a combination of Q10, L-arginine, and vitamin D could be a potential method to reduce myocardial injury or the effects of aging on the heart.Dec 31, 2017

Pubmed Data : J Vasc Res. 2018 ;55(1):47-60. Epub 2018 Jan 5. PMID: 29301117
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Arginine, Coenzyme Q10, Vitamin D
Diseases : Aging: Heart, Heart Failure
Pharmacological Actions : Antioxidants, Cardioprotective, Vasodilator Agents
Additional Keywords : Natural Substance Synergy
[+]

These results indicate the positive effects of Aronia melanocarpa supplementation on the age-dependent remodeling of coronary arteries.Apr 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Apr 23 ;11(9). Epub 2022 Apr 23. PMID: 35563943
Article Published Date : Apr 22, 2022
Study Type : Animal Study
Additional Links
Substances : Chokeberry
Diseases : Aging: Heart
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

These results suggested that naringenin has antiaging effects on myocardial cells.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:9536148. Epub 2017 Mar 12. PMID: 28386313
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Aging: Heart
Pharmacological Actions : Cardioprotective
[+]

Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 Dec ;18(6):4821-4830. Epub 2018 Oct 10. PMID: 30320398
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Formononetin
Diseases : Aging: Heart, Myocardial Ischemia
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
[+]

Ginsenoside Rb1 ameliorates age-related myocardial dysfunction.Dec 31, 2019

Pubmed Data : Am J Chin Med. 2020 ;48(6):1369-1383. Epub 2020 Sep 13. PMID: 32933311
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Aging: Heart
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Additional Keywords : Phytotherapy
[+]

Stem cell-derived exosomes prevent aging-induced cardiac dysfunction.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:9739258. Epub 2019 Apr 8. PMID: 31089420
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Aging: Heart, Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
Additional Keywords : Exosomes
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The citrus flavonoid naringenin protects the myocardium from Ageing-dependent dysfunction: potential role of SIRT1.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:4650207. Epub 2020 Jan 25. PMID: 32047577
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Naringenin
Diseases : Aging: Heart
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-6 Downregulation, SIRT1 Activator, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Copyright: pablofdezr / 123RF Stock Photo

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