Alcohol Withdrawal

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22 Substances Researched for Alcohol Withdrawal
NameACCKFocus
Ayahuasca322Locked
Ashwagandha314Locked
Magnesium110Locked
Cannabidiol24Locked
NAC (N-acetyl-L-cysteine)24Locked
Shilajit24Locked
Bacopa12Locked
Coenzyme Q1012Locked
Crocin12Locked
Curcumin12Locked
Delta-tetrahydrocannabinol (THC)12Locked
Green Tea12Locked
Holy Basil12Locked
Kratom12Locked
Kudzu12Locked
Lavender12Locked
Passion Flower12Locked
Quercetin12Locked
Saffron12Locked
St. Johns Wort12Locked
Triphala12Locked
Vanillin12Locked
5 Therapeutic Actions Researched for Alcohol Withdrawal
NameACCKFocus
Dietary Modification: Low Carbohydrate/Ketogenic212Locked
Acupuncture110Locked
Massage/Therapeutic Touch110Locked
Mindfullness Training110Locked
Electroacupuncture23Locked

View the Evidence:
32 Abstracts with Alcohol Withdrawal Research

[+]

"Rapid Partial Regeneration of Brain Volume During the First 14 Days of Abstinence from Alcohol."Oct 15, 2012

Pubmed Data : Alcohol Clin Exp Res. 2012 Oct 16. Epub 2012 Oct 16. PMID: 23072363
Article Published Date : Oct 15, 2012
Study Type : Human Study
Additional Links
Diseases : Alcohol Withdrawal
[+]

Acupuncture is effective as an adjunctive treatment to carbamazepine for the treatment of alcohol withdrawal symptoms.Oct 01, 2002

Pubmed Data : Addict Biol. 2002 Oct;7(4):415-9. PMID: 14578018
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Diseases : Alcohol Withdrawal
Therapeutic Actions : Acupuncture
[+]

Ashwaganda attenuates withdrawal-induced anxiety due to chronic ethanol consumption.Jun 01, 2008

Pubmed Data : Indian J Exp Biol. 2008 Jun;46(6):470-5. PMID: 18697607
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Ashwagandha
Diseases : Alcohol Withdrawal
[+]

Hazardous alcohol use and likely dependence increased month-by-month for those under lockdowns compared to those not under restrictions.Dec 24, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Psychiatry Res. 2020 Dec 25 ;296:113676. Epub 2020 Dec 25. PMID: 33385782
Article Published Date : Dec 24, 2020
Study Type : Human Study
Additional Links
Diseases : Alcohol Addiction, Alcohol Withdrawal
Additional Keywords : Increased Risk, Stay-at-home orders
[+]

Hypotheses regarding the mechanisms of ayahuasca in the treatment of addictions.Jun 30, 2012

Pubmed Data : J Psychoactive Drugs. 2012 Jul-Aug;44(3):200-8. PMID: 23061319
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Substances : Ayahuasca
Diseases : Alcohol Addiction, Alcohol Withdrawal, Drug Addiction
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Hypotheses regarding the mechanisms of ayahuasca in the treatment of addictions.Jun 30, 2012

Pubmed Data : J Psychoactive Drugs. 2012 Jul-Aug;44(3):200-8. PMID: 23061319
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Substances : Ayahuasca
Diseases : Alcohol Addiction, Alcohol Withdrawal, Drug Addiction
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Adv. 2021 Apr ;7(15). Epub 2021 Apr 9. PMID: 33837086
Article Published Date : Mar 31, 2021
Study Type : Animal Study, Human Study
Additional Links
Diseases : Alcohol Withdrawal, Brain Inflammation
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Risk Reduction
[+]

Low serum magnesium and 1-year mortality in alcohol withdrawal syndrome.Aug 31, 2019

Pubmed Data : Eur J Clin Invest. 2019 Sep ;49(9):e13152. Epub 2019 Jul 1. PMID: 31216056
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Alcohol Withdrawal, All-Cause Mortality, Magnesium Deficiency
Additional Keywords : Increased Risk
[+]

Massage therapy improves the management of alcohol withdrawal syndrome. Apr 01, 2005

Pubmed Data : J Altern Complement Med. 2005 Apr;11(2):311-3. PMID: 15865498
Article Published Date : Apr 01, 2005
Study Type : Human Study
Additional Links
Diseases : Alcohol Withdrawal
Therapeutic Actions : Massage/Therapeutic Touch
[+]

Mindfulness practice predicts interleukin-6 responses to a mindfulness-based alcohol relapse prevention intervention.Sep 30, 2019

Pubmed Data : J Subst Abuse Treat. 2019 Oct ;105:57-63. Epub 2019 Aug 1. PMID: 31443893
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Diseases : Alcohol Addiction, Alcohol Withdrawal
Therapeutic Actions : Mindfullness Training
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

A polyherbal formula is comparable to the benzodiazepiene drug alprazolam in reducing ethanol withdrawal-induced anxiety behavior. Jan 01, 2011

Pubmed Data : Evid Based Complement Alternat Med. 2011;2011. Epub 2010 Sep 7. PMID: 20953426
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Ashwagandha, Green Tea, Holy Basil, Shilajit, Triphala
Diseases : Alcohol Withdrawal, Anxiety Disorders
Additional Keywords : Benzodiazepine Alternatives, Drug: Alprazolam, Natural Substances Versus Drugs
[+]

Ayahuasca inhibits early behaviors associated with the initiation and development of ethanol addiction and also showed effectiveness in reversing long-term drug effects expression.Mar 31, 2015

Pubmed Data : Physiol Behav. 2015 Apr 1 ;142:28-36. Epub 2015 Jan 28. PMID: 25637859
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ayahuasca
Diseases : Alcohol Addiction, Alcohol Withdrawal, Alcoholism
[+]

Bacopa monnieri abrogates alcohol abstinence-induced anxiety-like behaviour.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Mar ;111:1417-1428. Epub 2019 Jan 19. PMID: 30841457
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Alcohol Withdrawal, Anxiety
Pharmacological Actions : Anti-Anxiety Agents
[+]

Cannabidiol reduces ethanol consumption, motivation and relapse in mice.Feb 12, 2017

Pubmed Data : Addict Biol. 2017 Feb 13. Epub 2017 Feb 13. PMID: 28194850
Article Published Date : Feb 12, 2017
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Alcohol Withdrawal
[+]

Curcumin may contribute to ameliorating alcohol withdrawal symptoms. Dec 01, 2007

Pubmed Data : Cell Mol Neurobiol. 2007 Dec;27(8):997-1006. Epub 2007 Sep 11. PMID: 17846884
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Alcohol Withdrawal
[+]

Effects of cannabidiol, with and without ∆9-tetrahydrocannabinol, on anxiety-like behavior following alcohol withdrawal.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2024 ;18:1375440. Epub 2024 Jun 18. PMID: 38957186
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)
Diseases : Alcohol Withdrawal, Anxiety
Pharmacological Actions : Anti-Anxiety Agents
[+]

Effects of ketogenic diet and ketone monoester supplement on acute alcohol withdrawal symptoms.Feb 28, 2021

Pubmed Data : Psychopharmacology (Berl). 2021 Mar ;238(3):833-844. Epub 2021 Jan 7. PMID: 33410985
Article Published Date : Feb 28, 2021
Study Type : Animal Study
Additional Links
Diseases : Alcohol Withdrawal
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
[+]

Electroacupuncture inhibits CB1 upregulation induced by ethanol withdrawal in mice.Jun 30, 2012

Pubmed Data : Neurochem Int. 2012 Jul ;61(2):277-85. Epub 2012 May 18. PMID: 22613131
Article Published Date : Jun 30, 2012
Study Type : Animal Study
Additional Links
Diseases : Alcohol Withdrawal
Therapeutic Actions : Electroacupuncture
Additional Keywords : Cannabinoid Receptors
[+]

Elevated oxidation of DHA occurs in the brains of rats undergoing alcohol withdrawal. Sep 25, 2006

Pubmed Data : Neurosci Lett. 2006 Sep 25;405(3):172-4. Epub 2006 Jul 26. PMID: 16875780
Article Published Date : Sep 25, 2006
Study Type : Animal Study
Additional Links
Diseases : Alcohol Withdrawal
[+]

Kratom (M. speciosa) inhibit alcohol withdrawal-induced behaviors in mice. Apr 01, 2007

Pubmed Data : Fitoterapia. 2007 Apr;78(3):182-5. Epub 2007 Feb 6. PMID: 17335995
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Substances : Kratom
Diseases : Alcohol Withdrawal
[+]

Kudzu root suppresses voluntary alcohol intake and alcohol withdrawal symptoms in rats. Jun 01, 2004

Pubmed Data : J Med Food. 2004 Summer;7(2):168-79. PMID: 15298764
Article Published Date : Jun 01, 2004
Study Type : Animal Study
Additional Links
Substances : Kudzu
Diseases : Alcohol Withdrawal, Alcoholism
[+]

Lavender essential oil alleviates depressive-like behavior in alcohol-withdrawn rats.Jun 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2024 Jul ;176:116835. Epub 2024 May 28. PMID: 38810402
Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lavender
Diseases : Alcohol Withdrawal, Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

N-Acetylcysteine normalizes brain oxidative stress and neuroinflammation observed after protracted ethanol abstinence.Jan 27, 2023

Pubmed Data : Psychopharmacology (Berl). 2023 Jan 28. Epub 2023 Jan 28. PMID: 36708386
Article Published Date : Jan 27, 2023
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Alcohol Withdrawal, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Oral administration of coenzyme Q10 ameliorates memory impairment induced by nicotine-ethanol abstinence.May 17, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2024 May 18 ;14(1):11413. Epub 2024 May 18. PMID: 38762560
Article Published Date : May 17, 2024
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Alcohol Withdrawal, Smoking Cessation: Nicotine Addiction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

P. incarnata treatment might be a potential therapy in the alcohol withdrawal syndrome.Jul 31, 2017

Pubmed Data : Phytother Res. 2017 Aug ;31(8):1199-1208. Epub 2017 Jun 1. PMID: 28568647
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Alcohol Withdrawal
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Interleukin-10 upregulation
Additional Keywords : Plant Extracts
[+]

Quercetin has a protective effect in the management of alcohol withdrawal reactions. Sep 01, 2002

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2002 Sep;48(6):685-92. PMID: 16176153
Article Published Date : Sep 01, 2002
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Alcohol Withdrawal
[+]

St. John's wort reduces symptoms of alcohol withdrawal in rats. Oct 01, 2006

Pubmed Data : Fundam Clin Pharmacol. 2006 Oct;20(5):481-8. PMID: 16968419
Article Published Date : Oct 01, 2006
Study Type : Animal Study
Additional Links
Substances : St. Johns Wort
Diseases : Alcohol Withdrawal
[+]

The aqueous extract of saffron and crocin can be considered as safe agents and reliable alternative to diazepam in management of ethanol withdrawal syndrome.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2018 Dec ;21(4):277-283. Epub 2018 Dec 31. PMID: 30652054
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Crocin, Saffron
Diseases : Alcohol Withdrawal
Pharmacological Actions : Prophylactic Agents
[+]

The results of the study reveal that NAC has remarkable protective effects in the alcohol abstinence-induced depression.Apr 24, 2018

Pubmed Data : Neurochem Int. 2018 Apr 25 ;118:73-81. Epub 2018 Apr 25. PMID: 29704590
Article Published Date : Apr 24, 2018
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Alcohol Withdrawal, Depression
Pharmacological Actions : Antidepressive Agents
[+]

Vanillin attenuates the ethanol withdrawal syndrome and ethanol withdrawal induced anxiety by regulating the neurochemical balance.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Neuropathol. 2022 ;60(3):316-323. PMID: 36382484
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Vanillin
Diseases : Alcohol Toxicity , Alcohol Withdrawal, Anxiety
[+]

Withinia Somnifera alone and in combination with Shilajeet prevented ethanol withdrawal and alcohol addiction.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2016 May ;12(Suppl 2):S121-8. Epub 2016 May 11. PMID: 27279696
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Ashwagandha, Shilajit
Diseases : Alcohol Addiction, Alcohol Withdrawal
[+]

Electroacupuncture relieves pain during alcohol withdrawal. Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Acupunct. 2020 Dec 1 ;32(6):357-361. Epub 2020 Dec 16. PMID: 33362887
Article Published Date : Nov 30, 2020
Study Type : Review
Additional Links
Diseases : Alcohol Withdrawal
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

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