Alopecia

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49 Substances Researched for Alopecia
NameACCKFocus
Garlic120Locked
Onion120Locked
Pumpkin Seed Oil/Meal214Locked
Vitamin D414Locked
Apple Polyphenols312Locked
Ginger212Locked
Ginseng (Korean)312Locked
Procyanidin B2 211Locked
Cayenne110Locked
EGCG (Epigallocatechin gallate)110Locked
Ginsenosides410Locked
Isoflavones110Locked
Kimchi110Locked
Probiotics110Locked
Carnitine14Locked
Green Tea14Locked
Japanese cypress24Locked
Polyphenols14Locked
Saw Palmetto24Locked
Biotin23Locked
AHCC12Locked
Apples12Locked
Asiasari radix12Locked
Bee Venom12Locked
Black Currant12Locked
False Daisy12Locked
Fisetin12Locked
Formononetin12Locked
Ginkgo biloba12Locked
Ginseng12Locked
Hibiscus12Locked
Peppermint12Locked
Perilla 12Locked
Policosanol12Locked
Pumpkin12Locked
Red Clover12Locked
Safflower12Locked
Sophora Flavescens12Locked
Spikenard12Locked
Thuja 12Locked
Zhu Ling Mushroom 12Locked
Apigenin11Locked
Apple11Locked
Babchi11Locked
Curcumin11Locked
Erica multiflora11Locked
Grape Seed Extract11Locked
Schisandra11Locked
Turmeric11Locked
9 Problem Substances Researched for Alopecia
NameACCKFocus
Airborne Pollution120Locked
Polycyclic aromatic hydrocarbon120Locked
Atorvastatin13Locked
Paroxetine (trade names Seroxat, Paxil)13Locked
Statin Drugs13Locked
Tumor Necrosis Factor (TNF) Inhibitor Drugs13Locked
Hydrocarbons12Locked
Jet fuel12Locked
Sodium Fluoride11Locked
6 Therapeutic Actions Researched for Alopecia
NameACCKFocus
Laser Treatment 120Locked
Light Therapy120Locked
Laser Treatment: Low-Level312Locked
Hypnosis110Locked
Light-Emitting Diode Therapy26Locked
Microbiota Transfer Therapy26Locked
3 Problematic Actions Researched for Alopecia
NameACCKFocus
Vaccination: All528Locked
Vaccination: Hepatitis B212Locked
Vaccination: Tetanus13Locked

View the Evidence:
100 Abstracts with Alopecia Research

[+]

Air pollution may contribute to hair loss.Sep 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2019 Sep 10 ;116(37):18410-18415. Epub 2019 Aug 26. PMID: 31451642
Article Published Date : Sep 10, 2019
Study Type : Human Study
Additional Links
Diseases : Alopecia, Hair Loss
Problem Substances : Airborne Pollution, Polycyclic aromatic hydrocarbon
[+]

Apple procyanidin B2 on keratin biosynthesis in vitro, and highlights its effect as a nutraceutical on human hair growth and tropism.Sep 27, 2017

Pubmed Data : J Med Food. 2017 Sep 28. Epub 2017 Sep 28. PMID: 28956697
Article Published Date : Sep 27, 2017
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Apple Polyphenols, Procyanidin B2
Diseases : Hair Loss
Additional Keywords : Hair Regeneration, Procyanidins
[+]

Capsaicin and isoflavone promotes hair growth in mice and humans with alopecia. Oct 01, 2007

Pubmed Data : Growth Horm IGF Res. 2007 Oct;17(5):408-15. Epub 2007 Jun 13. PMID: 17569567
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Substances : Cayenne, Isoflavones
Diseases : Alopecia
Additional Keywords : Insulin-Like Growth Factor
[+]

Comparison of low-level light therapy and combination therapy of 5% minoxidil in the treatment of female pattern hair loss.Oct 16, 2020

Pubmed Data : Lasers Med Sci. 2020 Oct 17. Epub 2020 Oct 17. PMID: 33068178
Article Published Date : Oct 16, 2020
Study Type : Human Study
Additional Links
Diseases : Hair Loss
Therapeutic Actions : Laser Treatment: Low-Level
[+]

Findings of the present trial provide evidence of a promising potential role of pumpkin seed oil in treating female pattern hair loss.Feb 04, 2021

Pubmed Data : J Cosmet Dermatol. 2021 Feb 5. Epub 2021 Feb 5. PMID: 33544448
Article Published Date : Feb 04, 2021
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Hair Loss
[+]

Garlic gel increases the efficacy of betamethasone valerate cream in the treatment of localized alopecia areata. Jan 01, 2007

Pubmed Data : Indian J Dermatol Venereol Leprol. 2007 Jan-Feb;73(1):29-32. PMID: 17314444
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Garlic
Diseases : Alopecia, Hair Loss
[+]

Ginger improves oxidative stress and trace elements status in patients with alopecia areata.Oct 31, 2020

Pubmed Data : Niger J Clin Pract. 2020 Nov ;23(11):1555-1560. PMID: 33221781
Article Published Date : Oct 31, 2020
Study Type : Human Study
Additional Links
Substances : Ginger
Diseases : Alopecia, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Hepatitis B vaccination significantly increases the risk of a wide range of autoimmune diseases.Jun 01, 2005

Pubmed Data : Autoimmunity. 2005 Jun;38(4):295-301. PMID: 16206512
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Diseases : Alopecia, Arthritis, Hepatitis B , Lupus Erythematosus: Systemic, Optic Neuritis, Rheumatoid Arthritis, Thrombocytopenia, Vasculitis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

High sugar-sweetened beverage consumption is associated with a higher risk of male pattern hair loss.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jan 1 ;15(1). Epub 2023 Jan 1. PMID: 36615870
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Diseases : Hair Loss
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

Hypnotic interventions may ameliorate the clinical outcome of patients with Alopeica areata and may improve their psychological well-being. Jul 01, 2008

Pubmed Data : Int J Clin Exp Hypn. 2008 Jul;56(3):318-33. PMID: 18569142
Article Published Date : Jul 01, 2008
Study Type : Human Study
Additional Links
Diseases : Alopecia
Therapeutic Actions : Hypnosis
[+]

Kimchi and cheonggukjang probiotic product could promote hair growth and reverse hair loss without associated adverse effects such as diarrhea.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Mens Health. 2020 Jan ;38(1):95-102. Epub 2019 Aug 5. PMID: 31385480
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Kimchi, Probiotics
Diseases : Alopecia: Androgenic, Hair Loss
Additional Keywords : Hair Regeneration
[+]

Low-level light (laser therapy) may have therapeutic value in stimulating hair growth. Jun 01, 2009

Pubmed Data : J Cosmet Laser Ther. 2009 Jun;11(2):110-7. PMID: 19466643
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Alopecia, Hair Loss
Therapeutic Actions : Laser Treatment , Light Therapy
[+]

Onion juice applied topically has significant effect on stimulating hair re-growth. Jun 01, 2002

Pubmed Data : J Dermatol. 2002 Jun;29(6):343-6. PMID: 12126069
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Substances : Onion
Diseases : Alopecia, Hair Loss
[+]

Oral intake of Pycnogenol might have the potential to reduce hair loss in postmenopausal women.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Health Sci Rep. 2023 Jan ;6(1):e1045. Epub 2023 Jan 6. PMID: 36620515
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Hair Loss
[+]

Preparation and optimization of garlic oil/apple vider vinegar nanoemulsion loaded with minoxidil to treat alopecia.Dec 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2021 Dec 14 ;13(12). Epub 2021 Dec 14. PMID: 34959435
Article Published Date : Dec 13, 2021
Study Type : Human Study
Additional Links
Substances : Apple Cider Vinegar, Garlic
Diseases : Alopecia
Additional Keywords : Natural Substance/Drug Synergy
[+]

The oral supplement assessed in this study safely and effectively promotes significant hair growth in women with temporary hair thinning.Oct 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Aesthet Dermatol. 2012 Nov ;5(11):28-34. PMID: 23198010
Article Published Date : Oct 31, 2012
Study Type : Human Study
Additional Links
Substances : Cherry: All Varieties, Orange, Silica
Diseases : Hair Loss
Additional Keywords : Hair Regeneration
[+]

There may be an association between vaccinations and hair loss.Oct 08, 1997

Pubmed Data : JAMA. 1997 Oct 8 ;278(14):1176-8. PMID: 9326478
Article Published Date : Oct 08, 1997
Study Type : Human Study
Additional Links
Diseases : Hair Loss, Hair Loss: Drug-Induced, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
[+]

These findings highlighted the potential use of watercress extract for the treatment of hair loss.Feb 07, 2022

Pubmed Data : Int J Cosmet Sci. 2022 Feb 8. Epub 2022 Feb 8. PMID: 35133683
Article Published Date : Feb 07, 2022
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Watercress
Diseases : Alopecia: Androgenic, Hair Loss
[+]

Vitamin D deficiency may be one of the factors having a role either in etiopathogenesis or exacerbation of alopecia areata.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Trichology. 2019 Mar-Apr;11(2):49-57. PMID: 31007473
Article Published Date : Feb 28, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Alopecia, Vitamin D Deficiency
[+]

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Dermatol. 2016 Jun ;28(3):327-34. Epub 2016 May 25. PMID: 27274631
Article Published Date : May 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Alopecia, Hair Loss
Pharmacological Actions : Anti-Apoptotic, MicroRNA modulator
[+]

Exosomes derived from human dermal papilla cells promote hair growth in cultured human hair follicles.Mar 28, 2019

Pubmed Data : Exp Dermatol. 2019 Mar 29. Epub 2019 Mar 29. PMID: 30924959
Article Published Date : Mar 28, 2019
Study Type : Animal Study, Human In Vitro
Additional Links
Diseases : Hair Loss
Additional Keywords : Exosomes
[+]

Korean red ginseng may protect against chemotherapy-induced alopecia.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2016 Apr ;40(2):169-75. Epub 2015 Jul 18. PMID: 27158238
Article Published Date : Mar 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Ginseng (Korean)
Diseases : Alopecia, Chemotherapy and Radiation Toxicity
Pharmacological Actions : Chemoprotective Agents
[+]

Light-emitting diodes have a potential to stimulate human dermal papilla cell proliferation.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Dermatol. 2017 Dec ;29(6):747-754. Epub 2017 Oct 30. PMID: 29200764
Article Published Date : Nov 30, 2017
Study Type : Human In Vitro
Additional Links
Diseases : Hair Loss
Therapeutic Actions : Light-Emitting Diode Therapy
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
[+]

Red ginseng extract promotes the hair growth in cultured human hair follicles.Feb 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2015 Mar ;18(3):354-62. Epub 2014 Nov 14. PMID: 25396716
Article Published Date : Feb 28, 2015
Study Type : Human In Vitro
Additional Links
Substances : Ginseng (Korean), Ginsenosides
Diseases : Hair Loss
Pharmacological Actions : Antiproliferative
Additional Keywords : Hair Regeneration, Plant Extracts
[+]

A case Report of aopecia areata treated with individualized homoeopathy. Oct 14, 2021

Pubmed Data : Altern Ther Health Med. 2021 Oct 15. Epub 2021 Oct 15. PMID: 34653026
Article Published Date : Oct 14, 2021
Study Type : Human: Case Report
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Alopecia
[+]

A case report of total hair loss after routine tetanus toxoid vaccination.Mar 19, 2011

Pubmed Data : Med Clin (Barc). 2011 Mar 19 ;136(7):318. Epub 2010 May 7. PMID: 20451934
Article Published Date : Mar 19, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Hair Loss, Hair Loss: Drug-Induced, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Tetanus
[+]

Adverse effects of tumor necrosis factor inhibitors include the development of alopecia.Jun 14, 2017

Pubmed Data : Dermatol Online J. 2017 Jun 15 ;23(6). Epub 2017 Jun 15. PMID: 28633753
Article Published Date : Jun 14, 2017
Study Type : Human: Case Report
Additional Links
Diseases : Alopecia
Additional Keywords : Alopecia, Tumor Necrosis Factor (TNF) Inhibitor Drugs
Problem Substances : Tumor Necrosis Factor (TNF) Inhibitor Drugs
[+]

Alopecia associated with atorvastatin has been reported. Aug 01, 2002

Pubmed Data : Am J Med. 2002 Aug 1 ;113(2):171. PMID: 12133763
Article Published Date : Aug 01, 2002
Study Type : Human: Case Report
Additional Links
Diseases : Alopecia, Statin-Induced Pathologies
Problem Substances : Atorvastatin, Statin Drugs
[+]

Fecal microbiota transplantation might act as a potential therapy for patients who suffer from alopecia areata.Oct 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Clin Cases. 2019 Oct 6 ;7(19):3074-3081. PMID: 31624757
Article Published Date : Oct 05, 2019
Study Type : Human: Case Report, Review
Additional Links
Diseases : Alopecia
Therapeutic Actions : Microbiota Transfer Therapy
Additional Keywords : Hair Regeneration
[+]

Hair growth in two alopecia patients after fecal microbiota transplant.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACG Case Rep J. 2017 ;4:e107. Epub 2017 Sep 13. PMID: 28932754
Article Published Date : Dec 31, 2016
Study Type : Human: Case Report
Additional Links
Diseases : Alopecia
Therapeutic Actions : Microbiota Transfer Therapy
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory
Additional Keywords : Hair Regeneration, Microbiota
[+]

Hair loss associated with paroxetine treatment has been reported.Jul 01, 1999

Pubmed Data : Clin Neuropharmacol. 1999 Jul-Aug;22(4):246-7. PMID: 10442258
Article Published Date : Jul 01, 1999
Study Type : Human: Case Report
Additional Links
Diseases : Depression, Hair Loss
Problem Substances : Paroxetine (trade names Seroxat, Paxil)
[+]

Pumpkin seed oil-loaded niosomes for topical application: 5α-reductase inhibitory, anti-inflammatory, and in vivo anti-hair loss effects.Jul 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2022 Jul 27 ;15(8). Epub 2022 Jul 27. PMID: 36015077
Article Published Date : Jul 26, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Hair Loss
Pharmacological Actions : 5-alpha reductase inhibitor, Anti-Inflammatory Agents
[+]

Two case reports of alopecia areata after vaccination.May 01, 2016

Pubmed Data : Pediatr Dermatol. 2016 May ;33(3):e218-9. Epub 2016 Apr 13. PMID: 27071855
Article Published Date : May 01, 2016
Study Type : Human: Case Report
Additional Links
Diseases : Alopecia, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
[+]

AHCC prevents chemotherapy induced hair loss.Oct 01, 2009

Pubmed Data : Cancer Epidemiol. 2009 Oct;33(3-4):293-9. Epub 2009 Aug 20. PMID: 19699163
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : AHCC
Diseases : Chemotherapy-Induced Toxicity, Hair Loss
[+]

Asiasari radix has hair growth-promoting potential in treating hair loss. May 01, 2005

Pubmed Data : J Dermatol Sci. 2005 May;38(2):89-97. Epub 2005 Mar 19. PMID: 15862941
Article Published Date : May 01, 2005
Study Type : Animal Study
Additional Links
Substances : Asiasari radix
Diseases : Alopecia: Androgenic, Androgenic Alopecia, Hair Loss, Male Pattern Baldness
[+]

Bee venom is a potentially potent 5α-reductase inhibitor and hair growth promoter.Apr 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2016 Apr 2. Epub 2016 Apr 2. PMID: 27040904
Article Published Date : Apr 01, 2016
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Hair Loss
Pharmacological Actions : 5-alpha reductase inhibitor
Additional Keywords : Dose Response
[+]

Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.Oct 31, 2019

Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):499-504. PMID: 31763209
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Alopecia, Hair Loss
Additional Keywords : Hair Regeneration
[+]

Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized RatsMar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Apr 1 ;24(7). Epub 2019 Apr 1. PMID: 30939852
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Hair Loss
Additional Keywords : Ovariectomy-Induced Changes
[+]

Chamaecyparis obtusa oil can increase circulation that supplies nutrients required for hair growth.Dec 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Res. 2013 Dec 31 ;29(4):241-7. PMID: 24578794
Article Published Date : Dec 30, 2013
Study Type : Animal Study
Additional Links
Substances : Japanese cypress
Diseases : Hair Loss
Pharmacological Actions : Vascular Endothelial Growth Factor Regulator
Additional Keywords : Plant Oils
[+]

Eclipta alba (syn. False Daisy) promotes hair growth in rats. Aug 01, 2008

Pubmed Data : Arch Dermatol Res. 2008 Aug;300(7):357-64. Epub 2008 May 14. PMID: 18478241
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : False Daisy
Diseases : Hair Loss
[+]

Effects of baicalin on alopecia and the associated mechanism.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2022 ;2022:3139123. Epub 2022 Nov 18. PMID: 36440360
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Alopecia
Pharmacological Actions : Transforming growth factor beta (TGF-β) upregulation
[+]

Exfoliative dermatitis, depigmentation and alopecia are associated with biotin deficiency in animals. Jan 01, 1991

Pubmed Data : Schweiz Arch Tierheilkd. 1991;133(6):277-83. PMID: 1718031
Article Published Date : Jan 01, 1991
Study Type : Animal Study
Additional Links
Substances : Biotin
Diseases : Alopecia, Dermatitis: Exfoliative, Pigmentation Disorders
[+]

Extract of Pinus thunbergii bark may be utilized for hair loss prevention and/or hair growth promotion.Feb 28, 2022

Pubmed Data : Mol Med Rep. 2022 Mar ;25(3). Epub 2022 Jan 28. PMID: 35088884
Article Published Date : Feb 28, 2022
Study Type : Animal Study
Additional Links
Substances : Pine Bark Extract
Diseases : Hair Loss
Additional Keywords : Hair Regeneration
[+]

Fisetin promotes hair growth by augmenting TERT expression. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2020 ;8:566617. Epub 2020 Oct 15. PMID: 33178686
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Alopecia
Additional Keywords : Hair Regeneration
[+]

Garlic exosomes promote hair growth through the Wnt/β-catenin pathway and growth factors.Jun 30, 2023

Pubmed Data : Cureus. 2023 Jul ;15(7):e42142. Epub 2023 Jul 19. PMID: 37602007
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Hair Loss
Pharmacological Actions : Transforming growth factor beta (TGF-β) upregulation, Vascular Endothelial Growth Factor Regulator
[+]

Ginkgo biloba extract stimulates hair regrowth in mice. Oct 01, 1993

Pubmed Data : Yakugaku Zasshi. 1993 Oct;113(10):718-24. PMID: 8254481
Article Published Date : Oct 01, 1993
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Hair Loss
Additional Keywords : Plant Extracts
[+]

Ginsenoside F2 reduces hair loss by controlling apoptosis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2014 ;37(5):755-63. PMID: 24789999
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Hair Loss
Pharmacological Actions : Anti-Apoptotic
[+]

Hair growth activity of Crataegus pinnatifida on C57BL/6 mouse model.Aug 31, 2013

Pubmed Data : Phytother Res. 2013 Sep ;27(9):1352-7. Epub 2012 Nov 12. PMID: 23148028
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Hawthorn
Diseases : Hair Loss
Pharmacological Actions : Anti-Apoptotic, Bax/Bcl2 ratio: Increase
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]

Hair growth-promoting activity of hot water extract of Thuja orientalis.Jan 09, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2013 Jan 10 ;13:9. Epub 2013 Jan 10. PMID: 23305186
Article Published Date : Jan 09, 2013
Study Type : Animal Study
Additional Links
Substances : Thuja
Diseases : Hair Loss
Additional Keywords : Plant Extracts
[+]

Hair growth-promoting effect of Carthamus tinctorius floret extract.Jun 30, 2014

Pubmed Data : Phytother Res. 2014 Jul ;28(7):1030-6. Epub 2013 Dec 11. PMID: 24338940
Article Published Date : Jun 30, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Safflower
Diseases : Hair Loss
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Hair Regeneration, Plant Extracts
[+]

Hair growth-promoting mechanisms of red ginseng extract.Sep 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prev Nutr Food Sci. 2021 Sep 30 ;26(3):275-284. PMID: 34737988
Article Published Date : Sep 29, 2021
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Hair Loss
Pharmacological Actions : Antioxidants
[+]

Hibiscus leaf extract is more potent in encouraging hair gowth than the flower extract. Oct 01, 2003

Pubmed Data : J Ethnopharmacol. 2003 Oct;88(2-3):235-9. PMID: 12963149
Article Published Date : Oct 01, 2003
Study Type : Animal Study
Additional Links
Substances : Hibiscus
Diseases : Hair Loss
[+]

Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.Mar 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Toxicol. 2013 Apr ;36:104-16. Epub 2013 Jan 25. PMID: 23453003
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Hair Loss, Infertility: Male, Obesity, Polycystic Ovary Syndrome
Additional Keywords : DNA Methylation, Increased Risk, Transgenerational inheritance
Problem Substances : Hydrocarbons, Jet fuel
[+]

L-carnitine promotes hair gowth in vitroNov 01, 2007

Pubmed Data : Exp Dermatol. 2007 Nov;16(11):936-45. PMID: 17927577
Article Published Date : Nov 01, 2007
Study Type : Animal Study
Additional Links
Substances : Carnitine
Diseases : Alopecia, Hair Loss
[+]

Liposomal honokiol promotes hair growth.Jun 04, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Jun 5 ;141:111793. Epub 2021 Jun 5. PMID: 34098216
Article Published Date : Jun 04, 2021
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Alopecia
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Hair Regeneration
[+]

Minoxidil-loaded hyaluronic acid dissolving microneedles to alleviate hair loss in an alopecia animal model.Feb 20, 2022

Pubmed Data : Acta Biomater. 2022 Feb 21. Epub 2022 Feb 21. PMID: 35202857
Article Published Date : Feb 20, 2022
Study Type : Animal Study
Additional Links
Substances : Hyaluronic Acid
Diseases : Alopecia
[+]

Obesity accelerates hair thinning by stem cell-centric converging mechanisms.Jun 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nature. 2021 Jul ;595(7866):266-271. Epub 2021 Jun 23. PMID: 34163066
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Hair Loss, Inflammation, Obesity, Oxidative Stress
Additional Keywords : Increased Risk
[+]

Older female rats had a signficant increase in the time of onset of alopecia areata, suggesting that the hepatitis B vaccine may initiate disease in mice predisposed to alopecia areata.Apr 01, 2009

Pubmed Data : Vet Dermatol. 2009 Apr ;20(2):99-104. Epub 2009 Jan 17. PMID: 19175564
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Alopecia
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

Panax notoginseng saponins promote hair follicle growth.May 31, 2023

Pubmed Data : Chem Biol Drug Des. 2023 Jun ;101(6):1416-1424. Epub 2023 Mar 17. PMID: 36866966
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Alopecia
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
[+]

Peppermint oil remarkably promoted hair growth compared to that of Minoxidil without significant change of body weight gain and food efficiency.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Res. 2014 Dec ;30(4):297-304. PMID: 25584150
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Peppermint
Diseases : Hair Loss
Pharmacological Actions : Insulin-Like Growth Factor Enhancer/Upregulation
Additional Keywords : Essential Oils, Superiority of Natural Substances versus Drugs
[+]

Policosanol and white wax could act against testosterone-induced alopecia in mice.Apr 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 May ;89:438-446. Epub 2017 Feb 27. PMID: 28249244
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Policosanol
Diseases : Alopecia
[+]

Serenoa repens extracts promote hair regeneration and repair of hair loss.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2018 Jun ;22(12):4000-4008. PMID: 29949176
Article Published Date : May 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Saw Palmetto
Diseases : Hair Loss
Pharmacological Actions : Regenerative
Additional Keywords : Hair Regeneration
[+]

Sophora flavescens extract has hair growth-promoting potential. May 01, 1998

Pubmed Data : Z Naturforsch C. 1998 May-Jun;53(5-6):311-7. PMID: 12354419
Article Published Date : May 01, 1998
Study Type : Animal Study
Additional Links
Substances : Sophora Flavescens
Diseases : Hair Loss
[+]

Tea polyphenols contributes to significant hair regrowth in rodents experiencing spontaneous hair loss. Aug 01, 2005

Pubmed Data : J Natl Med Assoc. 2005 Aug;97(8):1165-9. PMID: 16173333
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Substances : Green Tea, Polyphenols
Diseases : Alopecia, Hair Loss
[+]

Terpenoid compounds from Spikenard could be useful for hair growth.Mar 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2011 Apr ;7(26):146-50. PMID: 21716625
Article Published Date : Mar 31, 2011
Study Type : Animal Study
Additional Links
Substances : Spikenard
Diseases : Hair Loss
[+]

Tetrahydroxystilbene glucoside effectively prevents apoptosis induced hair loss.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:1380146. Epub 2018 Apr 2. PMID: 29808162
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Hair Loss
Pharmacological Actions : Anti-Apoptotic
Additional Keywords : Hair Regeneration, Plant Extracts
[+]

The essential oils of Chamaecyparis obtusa promote hair growth in an animal model. Jul 01, 2009

Pubmed Data : Fitoterapia. 2009 Jul 1. PMID: 19576968
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Japanese cypress
Diseases : Hair Loss
[+]

The promotion of hair regrowth by topical application of a Perilla frutescens extract.Dec 31, 2017

Pubmed Data : J Nat Med. 2018 Jan ;72(1):96-105. Epub 2017 Sep 13. PMID: 28905175
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Perilla
Diseases : Hair Loss
Additional Keywords : Hair Regeneration
[+]

These findings demonstrate that formononetin exerted the hair regrowth effect on hair loss.Dec 31, 2015

Pubmed Data : Planta Med. 2016 Jan ;82(1-2):65-9. Epub 2016 Jan 12. PMID: 26756818
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Hair Loss
Pharmacological Actions : Anti-Apoptotic, Bcl-2 protein down-regulation
Additional Keywords : Hair Regeneration
[+]

Zhu Ling (P. umbellatus) mushroom contains a comound which may promote hair regrowth. Mar 01, 1994

Pubmed Data : Chem Pharm Bull (Tokyo). 1994 Mar;42(3):530-3. PMID: 8004697
Article Published Date : Mar 01, 1994
Study Type : Animal Study
Additional Links
Substances : Zhu Ling Mushroom
Diseases : Hair Loss
Additional Keywords : Plant Extracts
[+]

A review of herbal preparations for the treatment of hair loss.Nov 02, 2019

Pubmed Data : Arch Dermatol Res. 2019 Nov 3. Epub 2019 Nov 3. PMID: 31680216
Article Published Date : Nov 02, 2019
Study Type : Review
Additional Links
Substances : Ginger, Ginseng, Ginseng (Korean), Pumpkin, Red Clover, Saw Palmetto
Diseases : Alopecia, Hair Loss
[+]

Acorus calamus: a bio-reserve of medicinal values.Mar 27, 2018

Pubmed Data : J Basic Clin Physiol Pharmacol. 2018 Mar 28 ;29(2):107-122. PMID: 29389665
Article Published Date : Mar 27, 2018
Study Type : Review
Additional Links
Substances : Acorus calamus
Diseases : Arthritis, Asthma, Diarrhea, Dyspepsia, Hair Loss, Kidney Damage, Liver Damage, Neuralgia
Pharmacological Actions : Anti-Asthmatic Agents, Gastrointestinal Agents, Hepatoprotective, Renoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Activation of Wnt/β-catenin signaling is involved in hair growth-promoting effect of 655-nm red light and LED.Mar 31, 2018

Pubmed Data : Lasers Med Sci. 2018 Apr ;33(3):637-645. Epub 2018 Feb 21. PMID: 29468283
Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Alopecia
Therapeutic Actions : Light-Emitting Diode Therapy
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
Additional Keywords : Hair Regeneration
[+]

Annurca apple polyphenols ignite keratin production in hair follicles.Oct 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Oct 2 ;10(10). Epub 2018 Oct 2. PMID: 30279339
Article Published Date : Oct 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Hair Loss
[+]

Apigenin simulates hair growth in an in vitro model. Nov 01, 2009

Pubmed Data : Br J Sports Med. 2009 Nov;43(11):840-4. Epub 2008 Apr 2. PMID: 19277688
Article Published Date : Nov 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Alopecia: Androgenic, Hair Loss
[+]

Biotin supplementation may reverse hair loss in epileptics patients receiving valproic acid. Jun 01, 2009

Pubmed Data : Brain Dev. 2009 Jun;31(6):405-10. Epub 2008 Sep 23. PMID: 18814980
Article Published Date : Jun 01, 2009
Study Type : Commentary
Additional Links
Substances : Biotin
Diseases : Epilepsy, Hair Loss
[+]

Combination therapy of vitamin D analogs with corticosteroids might also be used in treating alopecia areata.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(9):5285-5300. Epub 2019 Sep 15. PMID: 31632510
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Alopecia
[+]

Erica multiflora induces hair growth in vivo. Jul 01, 2009

Pubmed Data : Nat Med (Tokyo). 2009 Jul;63(3):335-9. Epub 2009 Mar 10. PMID: 19267263
Article Published Date : Jul 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Erica multiflora
Diseases : Hair Loss
[+]

Exosomes derived from fisetin-treated keratinocytes mediate hair growth promotion.Jun 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jun 18 ;13(6). Epub 2021 Jun 18. PMID: 34207142
Article Published Date : Jun 17, 2021
Study Type : In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Hair Loss
Additional Keywords : Exosomes, Hair Regeneration
[+]

Ginsenoside Rg3 might increase hair growth through stimulation of hair follicle stem cells and it has the potential to be used in hair growth products.Jun 30, 2014

Pubmed Data : Phytother Res. 2014 Jul ;28(7):1088-95. Epub 2013 Dec 26. PMID: 24375856
Article Published Date : Jun 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Alopecia, Hair Loss
Pharmacological Actions : Vascular Endothelial Growth Factor Regulator
[+]

Glycyrrhizin micellar nanocarriers for topical delivery of baicalin to the hair follicles: A targeted approach tailored for alopecia treatment.Sep 24, 2022

Pubmed Data : Int J Pharm. 2022 Sep 25 ;625:122109. Epub 2022 Aug 13. PMID: 35973589
Article Published Date : Sep 24, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Glycyrrhizin
Diseases : Alopecia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Vascular Endothelial Growth Factor Inhibitors
[+]

Grapeseed procyanidin promotes proliferation of hair follicle cells. - Article 1Nov 01, 1998

Pubmed Data : Acta Derm Venereol. 1998 Nov;78(6):428-32. PMID: 9833041
Article Published Date : Nov 01, 1998
Study Type : In Vitro Study
Additional Links
Substances : Grape Seed Extract
Diseases : Alopecia: Androgenic, Androgenic Alopecia, Hair Loss, Male Pattern Baldness
[+]

Hair loss in patients with inflammatory bowel disease.Jun 30, 2013

Pubmed Data : Inflamm Bowel Dis. 2013 Jul ;19(8):1753-63. PMID: 23624889
Article Published Date : Jun 30, 2013
Study Type : Review
Additional Links
Diseases : Hair Loss, Hair Loss: Drug-Induced, Inflammatory Bowel Diseases
Additional Keywords : Risk Factors
[+]

Induction of hair keratins expression by an Annurca apple-based nutraceutical formulation in human follicular cells.Dec 12, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Dec 13 ;11(12). Epub 2019 Dec 13. PMID: 31847069
Article Published Date : Dec 12, 2019
Study Type : In Vitro Study
Additional Links
Substances : Apple, Apple Polyphenols, Procyanidin B2
Diseases : Hair Loss
Pharmacological Actions : Antioxidants
[+]

Low-level laser therapy appears to be effective for treating pattern hair loss in both men and women.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Skin Appendage Disord. 2020 Sep ;6(5):259-267. Epub 2020 Jul 7. PMID: 33088809
Article Published Date : Aug 31, 2020
Study Type : Review
Additional Links
Diseases : Alopecia: Androgenic, Hair Loss
Therapeutic Actions : Laser Treatment: Low-Level
[+]

Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway.Jan 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 09 13 ;8(1):13785. Epub 2018 Sep 13. PMID: 30213979
Article Published Date : Jan 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dogwood
Diseases : Hair Loss
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
[+]

Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cosmet Investig Dermatol. 2019 ;12:669-678. Epub 2019 Sep 6. PMID: 31686888
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Diseases : Alopecia
Therapeutic Actions : Laser Treatment: Low-Level
Additional Keywords : Hair Regeneration
[+]

Phyllanthus emblica extract-loaded transfersomes for hair follicle targeting: phytoconstituents, characterization, and hair growth promotion.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oleo Sci. 2022 ;71(7):1085-1096. PMID: 35781257
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Amla Fruit
Diseases : Alopecia
Pharmacological Actions : Antioxidants
[+]

Potential anti-alopecia constituents from Theobroma cacao.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Adv Pharm Technol Res. 2021 Apr-Jun;12(2):169-174. Epub 2021 Apr 27. PMID: 34159149
Article Published Date : Mar 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Cocoa
Diseases : Alopecia
[+]

Preparation and optimization of aloe ferox gel loaded with Finasteride-Oregano oil nanocubosomes for treatment of alopecia.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Deliv. 2022 Dec ;29(1):284-293. PMID: 35019794
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Aloe Ferox, Oregano
Diseases : Alopecia
[+]

Procyanidin B-2 from apples promotes hair growth.Feb 13, 2010

Pubmed Data : Sci Total Environ. 2010 Feb 13. Epub 2010 Feb 13. PMID: 11841365
Article Published Date : Feb 13, 2010
Study Type : In Vitro Study
Additional Links
Substances : Apples
Diseases : Alopecia, Hair Loss, Male Pattern Baldness
[+]

Psoralea corylifolia L: Ethnobotanical, biological, and chemical aspects: A review.Mar 31, 2018

Pubmed Data : Phytother Res. 2018 Apr ;32(4):597-615. Epub 2017 Dec 15. PMID: 29243333
Article Published Date : Mar 31, 2018
Study Type : Review
Additional Links
Substances : Babchi
Diseases : Alopecia, Cancers: All, Eczema, Inflammation, Leprosy, Psoriasis
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Cytotoxic, Vasodilator Agents
[+]

Resveratrol can promote hair growth and may be a potential candidate for the treatment of hair loss.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cosmet Investig Dermatol. 2021 ;14:1805-1814. Epub 2021 Nov 27. PMID: 34866922
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Hair Loss
[+]

Schisandra may have hair growth-promoting effects. Mar 01, 2009

Pubmed Data : Eur J Dermatol. 2009 Mar-Apr;19(2):119-25. Epub 2009 Jan 20. PMID: 19153064
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Schisandra
Diseases : Hair Loss
[+]

Sodium fluoride exposure compromises hair follicle growth and accelerates programmed cell death.Jan 05, 2010

Pubmed Data : Biol Trace Elem Res. 2010 Jan 5. Epub 2010 Jan 5. PMID: 20049553
Article Published Date : Jan 05, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Hair Loss, Hair Quality Problems
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Apoptotic, Oxidant
[+]

There is early evidence that turmeric/curcumin products and supplements, both oral and topical, may provide therapeutic benefits for skin health.May 22, 2016

Pubmed Data : Phytother Res. 2016 May 23. Epub 2016 May 23. PMID: 27213821
Article Published Date : May 22, 2016
Study Type : Review
Additional Links
Substances : Curcumin, Turmeric
Diseases : Acne, Alopecia, Atopic Dermatitis, Oral Lichen Planus, Pruritus, Psoriasis, Radiodermatitis, Vitiligo
[+]

This study reveals a novel mechanism by which ginsenoside promotes hair growth through p63 induction in follicular keratinocytes.Jun 30, 2013

Pubmed Data : Phytother Res. 2013 Jul ;27(7):1095-101. Epub 2012 Sep 25. PMID: 23007914
Article Published Date : Jun 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Hair Loss
Additional Keywords : Plant Extracts
[+]

Vitamin D supplementation could be a therapeutic option for patients with alopecia areata, female pattern hair loss, or telogen effluvium.Dec 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Dec 7 ;18(12). Epub 2017 Dec 7. PMID: 29215595
Article Published Date : Dec 06, 2017
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Alopecia, Hair Loss
[+]

Vitamin D3 may have therapeutic potential for hair regeneration.Jul 31, 2012

Pubmed Data : Stem Cells Transl Med. 2012 Aug ;1(8):615-26. Epub 2012 Jul 27. PMID: 23197867
Article Published Date : Jul 31, 2012
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Alopecia
Additional Keywords : Hair Regeneration
[+]

Procyanidin B-2 may provide an effective treatment for male pattern baldnessJun 01, 2001

Pubmed Data : Phytother Res. 2001 Jun;15(4):331-6. PMID: 11406858
Article Published Date : Jun 01, 2001
Additional Links
Diseases : Alopecia

Copyright: bigfatnapoleon / 123RF Stock Photo

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