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Alzheimer's Disease
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330 Substances Researched for Alzheimer's Disease
Name
AC
CK
Focus
Vitamin D
10
122
Curcumin
55
107
Huperzine
21
84
Ginkgo biloba
12
72
Folic Acid
13
63
Vitamin E
9
59
Melatonin
16
49
Ginsenosides
27
41
Vitamin B-12
4
40
Coconut Oil
9
38
Alpha-Lipoic Acid
9
33
Coffee
4
32
Sage
4
31
Vitamin B-6
3
30
Saffron
9
28
Resveratrol
24
27
Probiotics
6
26
B-complex
4
23
Caffeine
5
23
Omega-3 Fatty Acids
4
23
Polyunsaturated Fatty Acids (PUFAs)
5
23
NAC (N-acetyl-L-cysteine)
3
22
SAMe (S-adenosylmethionine)
3
22
Flavonoids
15
21
Polyphenols
16
21
Carnitine, Acetyl-L-
2
20
Berberine
13
18
Catechin
6
16
Green Tea
6
16
Thymoquinone
9
16
Vitamin C
10
16
Bacopa
9
15
Cannabidiol
13
15
EGCG (Epigallocatechin gallate)
11
15
Selenium
4
15
Astaxanthin
10
14
Coconut
4
14
Tanshinone IIA
8
14
Cannabis
4
13
Medium Chain Triglycerides
2
13
Sulforaphane
6
13
Apples
2
12
Lemon Balm
3
12
Nobiletin
6
12
Phosphatidylserine
2
12
Pomegranate
8
12
Puerarin
8
12
Rosemary
2
12
Lion's Mane (Hericium Erinaceus)
6
11
Lychee
5
11
Olive Oil
5
11
Carotenoids
1
10
DHA (Docosahexaenoic Acid)
7
10
Genistein
7
10
GlyceroPhosphoCholine (alpha-GPC)
1
10
Lutein
1
10
Melissa (Lemonbalm)
1
10
Monounsaturated fatty acids
1
10
Papaya: Fermented
1
10
Piperidines
1
10
Sea Cucumber
1
10
Silica
1
10
Silica: Orthosilicic acid
1
10
Thiamine (B-1)
1
10
Apigenin
5
9
Baicalein
6
9
Cinnamon
7
9
Gastrodin
5
9
Gotu Kola
7
9
Lycopene
5
9
Magnesium
5
9
Royal Jelly
5
9
Turmeric
8
9
Ashwagandha
5
8
Ginger
5
8
Honokiol
5
8
Luteolin
5
8
Quercetin
5
8
Anthocyanins
6
7
Cannabinoids
7
7
Coenzyme Q10
4
7
Stilbenes
6
7
Walnut
4
7
Amla Fruit
4
6
Goji
5
6
Hesperidin
3
6
Holy Basil
2
6
Phloretin
3
6
Reishi Mushroom
3
6
Rose
3
6
Syrian rue
3
6
Theanine
3
6
Thymol
3
6
Acetyl-l-carnitine
3
5
Asiatic Acid
4
5
Bee Venom
3
5
Blueberry
3
5
Bromelain
1
5
Brown Rice: Pre-Germinated
1
5
Chokeberry
3
5
Crocin
3
5
Fenugreek
3
5
Fucoidan
3
5
Moringa oleifera
3
5
Myricetin
3
5
Oleocanthal
1
5
Oleuropein
4
5
Persimmon
3
5
Piperine
3
5
Rosmarinic acid
3
5
Astragaloside
3
4
Bamboo
3
4
Barberry
3
4
Black Pepper
2
4
Citrus Peel
2
4
Ferulic acid
3
4
Fisetin
2
4
Fucoxanthin
3
4
Grape
2
4
Kimchi
2
4
Lavender: Essential Oil
2
4
Naringenin
4
4
Nigella sativa (aka Black Seed)
4
4
Olive
3
4
Passion Flower
2
4
Radish
2
4
Rosemaric Acid
2
4
Rutin
3
4
S-Adenosylmethionine (SAMe)
3
4
Antrodia camphorata
2
3
Bael
2
3
Caprylic Acid
1
3
Carnosic Acid
2
3
Coptis chinensis
2
3
Cranberry
2
3
Delta-tetrahydrocannabinol (THC)
3
3
Eugenol
2
3
Ginseng (Korean)
2
3
Hydrogen Water
2
3
Hydroxytyrosol
2
3
Hyperforin
2
3
Kudzu
2
3
Lotus
2
3
Mangiferin
2
3
Nicotinamide adenine dinucleotide (NADH)
2
3
Oleanolic acid
2
3
Palmitoylethanolamide
2
3
Panax Notoginseng
2
3
Perilla
2
3
Piperlongumine
2
3
Rice Bran
2
3
Spirulina
2
3
Wine
2
3
Zataria multiflora
2
3
Allicin
1
2
Angelica
1
2
Anise
1
2
Ayurvedic Formulation: Chyawanprash
1
2
Basil
1
2
Bay leaf
1
2
Betulinic acid
1
2
Bifidobacterium Breve
1
2
Bifidobacterium Lactis
1
2
Bifidobacterium Longum
1
2
Bilberry
1
2
Bitter Orange
1
2
Caffeic Acid
1
2
Caffeic acid phenethyl ester
1
2
Capparis spinosa (caper)
1
2
Carnosine
1
2
Chaga Mushroom (Inonotus obliquus)
1
2
Cocoa
2
2
Coconut Water
1
2
Crocetin
1
2
Curcuminoids
2
2
Date Seeds
1
2
Diosgenin
1
2
EPA (Eicosapentaenoic Acid)
1
2
Eicosanoyl-5-hydroxytryptamide (EHT)
1
2
Emodin
1
2
Epicatechin
1
2
Estradiol (E(2))
1
2
Evodia ruteacarpa
1
2
FOS (Fructooligosaccharides)
1
2
False Black Pepper
1
2
Fig
1
2
Folate
1
2
Frankincense
1
2
Gingerol
1
2
Ginseng
2
2
Gold (nanoparticles)
1
2
Grape Seed Extract
1
2
Grapefruit Seed Extract
1
2
Green Coffee Bean
1
2
Guarana
1
2
Isoflavones
1
2
Jujube
1
2
Krill
1
2
Lactobacillus Acidophilus
1
2
Lactobacillus fermentum
1
2
Lauric acid
2
2
Lavender
1
2
Loquat
1
2
Lupeol
1
2
Mango
1
2
Mango leaf
1
2
Mangosteen
2
2
Medicinal Mushrooms
2
2
Moxibustion
1
2
Mulberry
1
2
Myrtle
1
2
Nattokinase
1
2
Nettle
1
2
Niacin
1
2
Peony
1
2
Plum
1
2
Pomegranate Peel
1
2
Propolis: Bee
1
2
Prunella vulgaris
1
2
Pterostilbene
2
2
Punicalagin
2
2
Pycnogenol (Pine Bark)
1
2
Raisins
1
2
Raspberry
2
2
Red Sage
1
2
Red Wine Extract
2
2
Red Yeast Rice
1
2
Rhubarb
1
2
Rose Hips
1
2
Salvia miltiorrhiza
2
2
Sesamin
1
2
Silibinin
1
2
Soy
1
2
St. Johns Wort
1
2
Ume (Japanese apricot)
1
2
Ursolic Acid
1
2
Valerian
1
2
Vitamin B12: methylcobalamin
2
2
Wogonin
1
2
Yeast
1
2
Yerba Mate
1
2
Zinc
2
2
6-Shogaol
1
1
Almond
1
1
Arginine
1
1
Asparagus
1
1
Avocado
1
1
Bergamot
1
1
Bisdemethoxycurcumin
1
1
Black Raspberry
1
1
Blackberry
1
1
Broccoli Sprouts
1
1
Cannabichromene
1
1
Cannabigerol
1
1
Cardamom
1
1
Carpolobia lutea
1
1
Chinese Skullcap
1
1
Chromium
1
1
Cinnamaldehyde
1
1
Colostrum
1
1
Copper
1
1
Coriandrum sativum
1
1
Coumestrol
1
1
Culinary Herbs and Spices
1
1
Cyanidin
1
1
Cysteine (see N-Acetylcysteine)
1
1
Daidzein
1
1
Demethoxycurcumin
1
1
Devils Claw
1
1
Echinacea
1
1
Ellagic Acid
1
1
Endocannabinoids
1
1
Fermented Foods and Beverages
1
1
Fish Oil
1
1
Fruit: All
1
1
Gallic Acid
1
1
Garlic
1
1
Garlic: Aged
1
1
Genipin
1
1
Gynostemma
1
1
Haritaki (Terminalia chebula)
1
1
Hawthorn
1
1
Hazelnut
1
1
Honey
1
1
Hops
1
1
Icariin
1
1
Isoquercitrin
1
1
Kava Kava
1
1
Licorice
1
1
Lignans
1
1
Long Pepper
1
1
Lysine
1
1
Magnolol
1
1
Maple Syrup
1
1
Marijuana
1
1
Milk Thistle
1
1
Mistletoe
1
1
Mushrooms: All
1
1
Paeoniflorin
1
1
Panax Ginseng
1
1
Phytate
1
1
Piceatannol
1
1
Policosanol
1
1
Poria cocos
1
1
Prebiotics
1
1
Propolis: Brazillian
1
1
Rice: Black
1
1
Safranal
1
1
Sembung Leaf
1
1
Sesame Seeds
1
1
Spikenard
1
1
Spinach
1
1
Strawberry
1
1
Tangeretin
1
1
Tannic Acid
1
1
Theophylline
1
1
Thyme
1
1
Triptolide
1
1
Vegetables: All
1
1
Vitamin A
1
1
Vitamin B6
1
1
Vitexins
1
1
Water: Deep Sea
1
1
White Mulberry
1
1
Xanthohumol
1
1
Xanthones
1
1
Yellow Sweet Clover (Melilotus officinalis)
1
1
beta-Carotene
1
1
neohesperidin
1
1
Muira Puama
1
0
30 Problem Substances Researched for Alzheimer's Disease
Name
AC
CK
Focus
Donepezil (trade name Aricept)
6
73
Memantine
5
62
Aluminum
14
28
Cholinesterase Inhibitor Drugs
3
24
Aluminum Chloride
11
22
Antidepressants
1
20
Lead
3
13
Benzodiazepines
1
10
Hydrogenated Oil
1
10
Radon
1
10
Statin Drugs
1
10
Herbicides
1
5
Formaldehyde
2
4
Cadmium
2
3
Eptastigmine
1
3
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
2
3
Aluminum oxide
1
2
Antibiotics
1
2
Canola Oil
1
2
Glyphosate formulations
1
2
Heavy Metals
1
2
Monosodium Glutamate (MSG)
1
2
Roundup (herbicide)
1
2
Aluminium Cans
1
1
Bisphenol A
1
1
Galantamine
1
1
Pesticides
1
1
Proton-Pump Inhibitors
1
1
Rivastigmine
1
1
Sugary soda
1
1
20 Therapeutic Actions Researched for Alzheimer's Disease
Name
AC
CK
Focus
Exercise
37
125
Exercise: Aerobic
5
41
Music
5
41
Dietary Modification: Mediterranean Diet
3
30
Acupuncture
3
22
Meditation
4
22
Electroacupuncture
4
16
Light-Emitting Diodes (LEDs) Therapy
2
13
Integrative Medicine
2
11
Exercise: Cycling
1
10
Massage/Therapeutic Touch
1
10
Mindfullness Training
1
10
Sunlight exposure
1
10
Dietary Modification: Low Carbohydrate/Ketogenic
4
5
Fasting/Caloric Restriction
3
4
Hyperbaric Treatment
2
4
Laser Treatment: Low-Level
2
3
Aromatherapy
1
1
Mind-Body Therapies
1
1
Yoga
1
1
3 Problematic Actions Researched for Alzheimer's Disease
Name
AC
CK
Focus
Low Dose Ionizing Radiation
1
10
Shift Work
1
10
Electromagnetic Radiation: 2.4 GHz
1
2
Research Articles
871
Cumulative Knowledge Score
1409
Overall Research Rating
EXCELLENT
Related Topics
Alzheimer's Disease is a Sub of the following Topic
Neurodegenerative Diseases
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View the Evidence:
1168 Abstracts with Alzheimer's Disease Research
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Additional Research
Neurodegenerative Diseases
Dementia
Aging: Brain
[+]
21 percent of patients who receive donepezil discontinue treatment due to adverse side effects.
Dec 07, 2009
Click here to read the entire abstract
Pubmed Data
: Ugeskr Laeger. 2009 Dec 7;171(50):3690-3. PMID:
20003864
Article Published Date
: Dec 07, 2009
Study Type
: Meta Analysis
Additional Links
Diseases
:
Alzheimer's Disease
,
Diarrhea: Drug-Associated
Problem Substances
:
Donepezil (trade name Aricept)
[+]
Alzheimer disease is associated with a low concentration of serum vitamin E in older people.
Aug 22, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Geriatr Psychiatry. 2017 Aug 23. Epub 2017 Aug 23. PMID:
28833475
Article Published Date
: Aug 22, 2017
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin E
Diseases
:
Alzheimer's Disease
,
Vitamin E Deficiency
Additional Keywords
:
Risk Factors
[+]
Alzheimer's disease cases have lower serum vitamin D concentrations than matched controls.
Oct 04, 2012
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2012 Oct 5. Epub 2012 Oct 5. PMID:
23042216
Article Published Date
: Oct 04, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Vitamin D Deficiency
Additional Keywords
:
Neurosteroid Hormone
[+]
An increased peripheral level of inflammatory markers is associated with a modest increase in risk of all-cause dementia.
Mar 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Gerontol A Biol Sci Med Sci. 2013 Apr ;68(4):433-40. Epub 2012 Sep 14. PMID:
22982688
Article Published Date
: Mar 31, 2013
Study Type
: Meta Analysis
Additional Links
Diseases
:
Alzheimer's Disease
,
C-Reactive Protein
,
Dementia
,
Inflammation
Additional Keywords
:
Increased Risk
[+]
Antidepressant drug usage is associated with higher odds of Alzheimer’s disease and dementia.
Dec 27, 2016
Click here to read the entire abstract
Pubmed Data
: Depress Anxiety. 2016 Dec 28. Epub 2016 Dec 28. PMID:
28029715
Article Published Date
: Dec 27, 2016
Study Type
: Meta Analysis, Review
Additional Links
Diseases
:
Alzheimer's Disease
,
Dementia
Additional Keywords
:
Risk Factors
Problem Substances
:
Antidepressants
[+]
Available data indicates that lower vitamin D status may be associated with increased risk of developing AD and dementia.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2015 ;14(1):76. Epub 2015 Aug 1. PMID:
26231781
Article Published Date
: Dec 31, 2014
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Dementia
,
Vitamin D Deficiency
Additional Keywords
:
Risk Factors
[+]
Cholinesterase inhibitor drug use is associated with increased incidence of bradycardia.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Am Geriatr Soc. 2009 Nov;57(11):1997-2003. Epub 2009 Sep 28. PMID:
19793162
Article Published Date
: Nov 01, 2009
Study Type
: Meta Analysis
Additional Links
Diseases
:
Alzheimer's Disease
,
Bradycardia
,
Dementia
Problem Substances
:
Cholinesterase Inhibitor Drugs
,
Donepezil (trade name Aricept)
[+]
Donepezil and memantine are known to cause bradycardia and to reduce the epileptogenic threshold.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Therapie. 2010 May-Jun;65(3):255-9. Epub 2010 Aug 11. PMID:
20699079
Article Published Date
: May 01, 2010
Study Type
: Meta Analysis
Additional Links
Diseases
:
Alzheimer's Disease
,
Bradycardia
,
Epileptic Seizures
Problem Substances
:
Donepezil (trade name Aricept)
,
Memantine
[+]
Ginkgo biloba is potentially beneficial for the improvement of cognitive function in patients with mild cognitive impairment or Alzheimer's disease.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Curr Top Med Chem. 2016 ;16(5):520-8. PMID:
26268332
Article Published Date
: Dec 31, 2015
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Higher coffee consumption is associated with reduced risk for Alzheimer disease.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2016 Jun ;32(6):628-36. Epub 2015 Dec 31. PMID:
26944757
Article Published Date
: May 31, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Coffee
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
Additional Keywords
:
Risk Reduction
[+]
Higher levels of serum 25(OH)D was associated with a lower risk of dementia and Alzheimer's disease.
Feb 14, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2018 Feb 15:1-10. Epub 2018 Feb 15. PMID:
29447107
Article Published Date
: Feb 14, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Dementia
Additional Keywords
:
Risk Reduction
[+]
Huperzine A appears to have beneficial effects on improvement of cognitive function.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(9):e74916. Epub 2013 Sep 23. PMID:
24086396
Article Published Date
: Dec 31, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Huperzine
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Huperzine A is a well-tolerated drug that could significantly improve cognitive performance in patients with Alzheimer's disease and vascular dementia.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2014 ;2014:363985. Epub 2014 Feb 3. PMID:
24639880
Article Published Date
: Dec 31, 2013
Study Type
: Meta Analysis
Additional Links
Substances
:
Huperzine
Diseases
:
Alzheimer's Disease
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Memantine does not appear to have proven benefit for mild to moderate alzheimer disease.
Jan 01, 2005
Click here to read the entire abstract
Pubmed Data
: Cochrane Database Syst Rev. 2005(3):CD003154. Epub 2005 Jul 20. PMID:
16034889
Article Published Date
: Jan 01, 2005
Study Type
: Meta Analysis
Additional Links
Diseases
:
Alzheimer's Disease
,
Dementia
Problem Substances
:
Memantine
[+]
Meta-analytic findings suggested overall benefits of EGb 761 for stabilizing or slowing decline in cognition of subjects with cognitive impairment and dementia.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2015 ;43(2):605-11. PMID:
25352453
Article Published Date
: Dec 31, 2014
Study Type
: Meta Analysis
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
,
Significant Treatment Outcome
[+]
Results of this meta-analytic study suggested that T. gondii can be considered a risk factor for the development of Alzheimer's disease.
Sep 15, 2019
Click here to read the entire abstract
Pubmed Data
: Microb Pathog. 2019 Sep 16 ;137:103751. Epub 2019 Sep 16. PMID:
31536800
Article Published Date
: Sep 15, 2019
Study Type
: Meta Analysis, Review
Additional Links
Diseases
:
Alzheimer's Disease
,
Toxoplasma gondii Infection
Additional Keywords
:
Risk Factors
[+]
These findings indicate a potential therapeutic role of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucosidein Alzheimer's disease therapy.
Aug 25, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2016 Aug 26 ;16(1):320. Epub 2016 Aug 26. PMID:
27565551
Article Published Date
: Aug 25, 2016
Study Type
: Meta Analysis, Review
Additional Links
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
This meta-analysis provided some evidence that melatonin improves sleep quality in patients with AD and PD.
Aug 08, 2015
Click here to read the entire abstract
Pubmed Data
: Neurol Sci. 2015 Aug 9. Epub 2015 Aug 9. PMID:
26255301
Article Published Date
: Aug 08, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Melatonin
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
,
Parkinson's Disease
[+]
This study shows a strongly positive association between bacterial infection and Alzheimer's disease.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2015 ;43(3):957-66. PMID:
25182736
Article Published Date
: Dec 31, 2014
Study Type
: Meta Analysis
Additional Links
Diseases
:
Alzheimer's Disease
,
Bacterial Infections
,
Chlamydia pneumoniae
Additional Keywords
:
Increased Risk
[+]
Vitamin D deficiency as a risk factor for dementia and Alzheimer's disease: an updated meta-analysis.
Nov 12, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Neurol. 2019 Nov 13 ;19(1):284. Epub 2019 Nov 13. PMID:
31722673
Article Published Date
: Nov 12, 2019
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Dementia
,
Vitamin D Deficiency
Additional Keywords
:
Risk Factors
[+]
Vitamin D, cognition, and dementia: a systematic review and meta-analysis.
Sep 24, 2012
Click here to read the entire abstract
Pubmed Data
: Neurology. 2012 Sep 25 ;79(13):1397-405. PMID:
23008220
Article Published Date
: Sep 24, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Dementia
,
Dementia: Alzheimer Type
,
Vitamin D Deficiency
[+]
A multi-vitamin/nutrient formula has therapeutic value in early-stage Alzheimer's diease.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Am J Alzheimers Dis Other Demen. 2008 Dec-2009 Jan;23(6):571-85. Epub 2008 Dec 1. PMID:
19047474
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Carnitine, Acetyl-L-
,
Folic Acid
,
NAC (N-acetyl-L-cysteine)
,
SAMe (S-adenosylmethionine)
,
Vitamin B-6
,
Vitamin E
Diseases
:
Alzheimer's Disease
[+]
A multi-vitamin/nutrient formula has therapeutic value in moderate-stage to later-stage Alzheimer's diease.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Alzheimers Dis Other Demen. 2009 Feb-Mar;24(1):27-33. Epub 2008 Dec 3. PMID:
19056706
Article Published Date
: Feb 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Carnitine, Acetyl-L-
,
Folic Acid
,
NAC (N-acetyl-L-cysteine)
,
SAMe (S-adenosylmethionine)
,
Vitamin B-12
,
Vitamin E
Diseases
:
Alzheimer's Disease
[+]
A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae.
Feb 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Mar ;111:714-723. Epub 2019 Jan 3. PMID:
30611996
Article Published Date
: Feb 28, 2019
Study Type
: Human Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
A supplement containing huperzine A and curcumin in dementia patients and individuals with mild cognitive impairment had beneficial effects.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 ;63(1):75-78. PMID:
29614668
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Huperzine
Diseases
:
Alzheimer's Disease
,
Dementia with Lewy bodies (DLB)
Pharmacological Actions
:
Neuroprotective Agents
[+]
Acupuncture improves the overall function, cognition and activity of daily life in patients and the efficacy was superior to donepezil.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhen Jiu. 2014 Dec ;34(12):1156-60. PMID:
25876339
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Acupuncture
Additional Keywords
:
Donepezil Alternatives
,
Mind-Body Medicine
,
Therapeutic Action Superior to Drug Therapy
Problem Substances
:
Donepezil (trade name Aricept)
[+]
Acupuncture is a safe and is effective in improving the cognitive function and global clinical status of Alzheimer's disease.
Dec 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Dec 29 ;17(1):556. Epub 2017 Dec 29. PMID:
29284465
Article Published Date
: Dec 28, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Acupuncture
[+]
Adding medical cannabis oil to AD patients' pharmacotherapy is safe and a promising treatment option.
Jan 11, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2016 Jan 12. Epub 2016 Jan 12. PMID:
26757043
Article Published Date
: Jan 11, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
Diseases
:
Alzheimer's Disease
,
Dementia
[+]
Administration of saffron capsules was comparable with memantine in reducing cognitive decline in patients with moderate to severe AD.
Jun 30, 2014
Click here to read the entire abstract
Pubmed Data
: Hum Psychopharmacol. 2014 Jul ;29(4):351-9. PMID:
25163440
Article Published Date
: Jun 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Saffron
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Natural Substances Versus Drugs
,
Phytotherapy
,
Plant Extracts
Problem Substances
:
Memantine
[+]
Aerobic exercise in early Alzheimer’s disease is associated with benefits in functional ability.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(2):e0170547. Epub 2017 Feb 10. PMID:
28187125
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Neuroprotective Agents
[+]
Aerobic exercise sustains performance of instrumental activities of daily living in early-stage Alzheimer disease.
Dec 27, 2017
Click here to read the entire abstract
Pubmed Data
: J Geriatr Phys Ther. 2017 Dec 28. Epub 2017 Dec 28. PMID:
29286983
Article Published Date
: Dec 27, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Dementia
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Neuroprotective Agents
[+]
Aerobic fitness may have a positive influence on protection of brain even in aMCI CSF biomarker, a high-risk population to convert to AD.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Age (Dordr). 2016 Jun ;38(3):51. Epub 2016 Apr 23. PMID:
27106271
Article Published Date
: May 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Alpha lipoic acid is an anti-inflammatory and neuroprotective treatment for Alzheimer's disease.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Adv Drug Deliv Rev. 2008 Oct-Nov;60(13-14):1463-70. Epub 2008 Jul 4. PMID:
18655815
Article Published Date
: Oct 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Alpha lipoic appears to be an effective neuroprotective agent in Alzheimer's disease.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Neural Transm Suppl. 2007;(72):189-93. PMID:
17982894
Article Published Date
: Jan 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Alpha-GPC improves cognitive function in mild to moderate Alzhemier's dementia.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Clin Ther. 2003 Jan;25(1):178-93. PMID:
12637119
Article Published Date
: Jan 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
GlyceroPhosphoCholine (alpha-GPC)
Diseases
:
Alzheimer's Disease
[+]
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease.
Oct 07, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Alzheimers Dement. 2018 Oct 8. Epub 2018 Oct 8. PMID:
30337151
Article Published Date
: Oct 07, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Gut-brain Axis
[+]
Alzheimer's disease microbiome is associated with dysregulation of the anti-inflammatory P-glycoprotein pathway.
May 06, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: MBio. 2019 May 7 ;10(3). Epub 2019 May 7. PMID:
31064831
Article Published Date
: May 06, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Dysbiosis
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Microbiota
[+]
Antioxidant beverages could be used as a natural complementary therapy to alleviate or decrease oxidative stress in Alzheimer’s disease.
Aug 22, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2015 Aug 23. Epub 2015 Aug 23. PMID:
26298312
Article Published Date
: Aug 22, 2015
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Green Tea
Diseases
:
Alzheimer's Disease
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.
Jul 21, 2011
Click here to read the entire abstract
Pubmed Data
: Int J Geriatr Psychiatry. 2011 Jul 21. Epub 2011 Jul 21. PMID:
21780182
Article Published Date
: Jul 21, 2011
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
,
Vitamin B-12
,
Vitamin B-6
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
High Homocysteine
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Benzodiazepine and related drug use in general was associated with modestly increased risk of Alzheimer's disease.
May 30, 2018
Click here to read the entire abstract
Pubmed Data
: Acta Psychiatr Scand. 2018 May 31. Epub 2018 May 31. PMID:
29851063
Article Published Date
: May 30, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Risk Factors
Problem Substances
:
Benzodiazepines
[+]
Breath Qigong improves recognition in seniors With vascular cognitive impairment.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Altern Ther Health Med. 2019 Jan ;25(1):20-26. PMID:
30982783
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
Therapeutic Actions
:
Qigong
,
Therapeutic Breathing
Pharmacological Actions
:
Neuroprotective Agents
[+]
Caffeine given at breakfast significantly stimulated ketone production in a dose-dependent manner.
Nov 24, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 Nov 25. Epub 2016 Nov 25. PMID:
28177691
Article Published Date
: Nov 24, 2016
Study Type
: Human Study
Additional Links
Substances
:
Caffeine
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Dose Response
[+]
Caffeine in coffee can prevent and help brain function in Alzheimer's Disease
Sep 01, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Neuropharmacol. 2009 Sep ;7(3):207-16. PMID:
20190962
Article Published Date
: Sep 01, 2009
Study Type
: Human Study, Review, Transgenic Animal Study
Additional Links
Substances
:
Caffeine
,
Coffee
Diseases
:
Alzheimer's Disease
[+]
Chronic consumption of proton pump inhibitors may increase the risk for Alzheimer disease.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Clin Pharm Ther. 2010 Apr;35(2):125-6. PMID:
20456731
Article Published Date
: Apr 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain: Microglial Activation
,
Neurodegenerative Diseases
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Circulating vitamin D levels and Alzheimer's disease.
Dec 01, 2019
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2019 Dec 2. Epub 2019 Dec 2. PMID:
31815694
Article Published Date
: Dec 01, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Vitamin D Deficiency
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cocoa procyanidins attenuate lipid peroxidation associated neuronal cell death in a manner relevant to Alzheimer's disease.
May 15, 2009
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2009 May 15;46(10):1319-27. Epub 2009 Feb 25. PMID:
19248828
Article Published Date
: May 15, 2009
Study Type
: Human Study
Additional Links
Substances
:
Catechin
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Additional Keywords
:
Proanthocyanidins
[+]
Coconut oil was found to be beneficial in female patients with Alzheimer's dementia.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Hosp. 2015 ;32(6):2822-7. Epub 2015 Dec 1. PMID:
26667739
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Coconut Oil
Diseases
:
Alzheimer's Disease
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Consumption of strawberries and foods rich in vitamin C, pelargonidin, anthocyanidins, and total flavonoids may reduce the risk of Alzheimer's dementia.
Dec 13, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Dec 14 ;11(12). Epub 2019 Dec 14. PMID:
31847371
Article Published Date
: Dec 13, 2019
Study Type
: Human Study
Additional Links
Substances
:
Strawberry
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Curcumin appears to enhance clearance of amyloid-beta in Alzheimer's disease patients.
Sep 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2006 Sep;10(1):1-7. PMID:
16988474
Article Published Date
: Sep 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Disease Regression
[+]
Decreased brain volume in adults with childhood lead exposure.
May 26, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS Med. 2008 May 27 ;5(5):e112. PMID:
18507499
Article Published Date
: May 26, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Childhood Chemical Exposures
,
Childhood Cognitive Disorders
,
Lead Poisoning
,
Neurodegenerative Diseases
Problem Substances
:
Lead
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Decreased salivary lactoferrin levels are specific to Alzheimer's disease
Jun 18, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EBioMedicine. 2020 Jun 19:102834. Epub 2020 Jun 19. PMID:
32586758
Article Published Date
: Jun 18, 2020
Study Type
: Human Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Alzheimer's Disease
[+]
Dietary niacin may protect against Alzheimer's disease and age related cognitive decline.
Jul 31, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neurol Neurosurg Psychiatry. 2004 Aug ;75(8):1093-9. PMID:
15258207
Article Published Date
: Jul 31, 2004
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-3 (Niacin)
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Different brain regions are infected with fungi in Alzheimer’s disease.
Oct 14, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2015 Oct 15 ;5:15015. Epub 2015 Oct 15. PMID:
26468932
Article Published Date
: Oct 14, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Fungus Diseases
[+]
Docosahexaenoic acid-rich fish oil supplementation reduces kinase associated with insulin resistance in overweight and obese midlife adults.
May 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 May 30 ;12(6). Epub 2020 May 30. PMID:
32486256
Article Published Date
: May 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
Fish Oil
Diseases
:
Alzheimer's Disease
,
Diabetes Mellitus: Type 2
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Exercise capacity is strongly associated with cognitive function.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Mayo Clin Proc. 2017 Feb ;92(2):211-217. Epub 2017 Jan 9. PMID:
28082018
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Neuroprotective Agents
[+]
Exercise reduced neuropsychiatric symptoms in patients with mild Alzheimer's disease.
Dec 09, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Alzheimers Dis. 2015 Dec 10 ;50(2):443-53. PMID:
26682695
Article Published Date
: Dec 09, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Exercise
Additional Keywords
:
Dose Response
,
Risk Reduction
[+]
Fermented papaya has antioxidant actions in AD patients and that it may be a prophylactic food against neurological diseases associated with free radical overproduction.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2015 ;2015:624801. Epub 2015 Apr 7. PMID:
25944987
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Papaya: Fermented
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Significant Treatment Outcome
[+]
Folic acid deficiency may play a key role in neurodegenerative disorders.
Jun 15, 2007
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2007 Jun 15;420(3):213-6. Epub 2007 May 3. PMID:
17532571
Article Published Date
: Jun 15, 2007
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
Diseases
:
Alzheimer's Disease
,
Dementia
,
Lewy Body Disease
[+]
Gingko biloba compares favorably to the drug Aricept (donepezil) for the treatment of Alzheimer's dementia.
Sep 01, 2006
Click here to read the entire abstract
Pubmed Data
: Eur J Neurol. 2006 Sep;13(9):981-5. PMID:
16930364
Article Published Date
: Sep 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Ginkgo biloba
,
Piperidines
Diseases
:
Alzheimer's Disease
,
Dementia
Additional Keywords
:
Donepezil Alternatives
,
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Ginkgo biloba is as effective as the drug donepezil (Aricept) in improving symptoms of Alzheimers, but with less side effects.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Aging Ment Health. 2009 Mar;13(2):183-90. PMID:
19347685
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
Gram-negative bacterial molecules are associated with AD neuropathology.
Nov 28, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2016 Nov 29 ;87(22):2324-2332. Epub 2016 Oct 26. PMID:
27784770
Article Published Date
: Nov 28, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Gram-Negative Bacterial Infections
Additional Keywords
:
Risk Factors
[+]
High homocysteine levels may be associated with the pathogenesis of neurological disorders.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Front Biosci (Schol Ed). 2010;2:359-72. Epub 2010 Jan 1. PMID:
20036953
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
B-complex
Diseases
:
Alzheimer's Disease
,
Amyotrophic Lateral Sclerosis
,
Epilepsy
,
High Homocysteine
,
Hyperhomocysteinemia
,
Multiple Sclerosis
,
Parkinson's Disease
,
Stroke
Additional Keywords
:
Diseases that are Linked
[+]
High intake of polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) reduce the risk of cognitive decline and dementia associated with Alzheimer's disease and/or vascular dsyfunction.
Apr 01, 2005
Click here to read the entire abstract
Pubmed Data
: Exp Gerontol. 2005 Apr;40(4):257-70. PMID:
15820606
Article Published Date
: Apr 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Monounsaturated fatty acids
,
Omega-3 Fatty Acids
,
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
Alzheimer's Disease
,
Cerebrovascular Disorders
Additional Keywords
:
Risk Reduction
[+]
Higher dietary intakes of flavonols may be associated with reduced risk of developing Alzheimer dementia.
Jan 28, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2020 Jan 29. Epub 2020 Jan 29. PMID:
31996451
Article Published Date
: Jan 28, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Higher intake of hydrogenated fats may increase the risk of Alzheimer disease.
Feb 01, 2003
Click here to read the entire abstract
Pubmed Data
: Arch Neurol. 2003 Feb;60(2):194-200. PMID:
12580703
Article Published Date
: Feb 01, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Problem Substances
:
Hydrogenated Oil
[+]
Higher intake of polyunsaturated fatty acids (PUFA) and fish oil was associated with better semantic memory and global cognitive function.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Geriatr Psychiatry. 2008 Jul;23(7):741-7. PMID:
18188871
Article Published Date
: Jul 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
[+]
Higher levels of homocysteine and lower levels of folate and B vitamins are found in people with Alzheimer’s disease.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurobiol Aging. 2015 Jan ;36 Suppl 1:S203-10. Epub 2014 Aug 30. PMID:
25444607
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
B-complex
Diseases
:
Alzheimer's Disease
,
Alzheimer's Disease: Homocysteine Associated
[+]
Higher Mediterranean-style diet adherence was estimated to provide 1.5 to 3.5 years of protection against Alzheimer disease.
May 14, 2018
Click here to read the entire abstract
Pubmed Data
: Neurology. 2018 May 15 ;90(20):e1789-e1798. Epub 2018 Apr 13. PMID:
29653991
Article Published Date
: May 14, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Alzheimer's disease
,
Dietary Modification: Mediterranean Diet
,
Neuroprotective Agents
[+]
Higher vitamin D dietary intake was associated with a lower risk of developing Alzheimer's disease among older women.
Oct 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Gerontol A Biol Sci Med Sci. 2012 Nov ;67(11):1205-11. Epub 2012 Apr 13. PMID:
22503994
Article Published Date
: Oct 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Huperzine-A is effective in reducing cognitive and task switching deficits in patients with Alzheimer's disease.
Sep 06, 2018
Click here to read the entire abstract
Pubmed Data
: J Chin Med Assoc. 2018 Sep 7. Epub 2018 Sep 7. PMID:
30201189
Article Published Date
: Sep 06, 2018
Study Type
: Human Study
Additional Links
Substances
:
Huperzine
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Identification of fungal species in brain tissue from Alzheimer's disease by next-generation sequencing.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2017 ;58(1):55-67. PMID:
28387676
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Fungus Diseases
Additional Keywords
:
Fungal Proteins
,
Risk Factors
[+]
Increasing energy output from a variety of physical activities is related to larger gray matter volumes in the elderly, regardless of cognitive status.
Mar 10, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Alzheimers Dis. 2016 Mar 11. Epub 2016 Mar 11. PMID:
26967227
Article Published Date
: Mar 10, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
,
Sitting Sickness
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Factors
,
Risk Reduction
[+]
Infection of fungi and bacteria in brain tissue from elderly persons and patients with Alzheimer's disease.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2018 ;10:159. Epub 2018 May 24. PMID:
29881346
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Bacterial Infections
,
Fungal Infection
Additional Keywords
:
Risk Factors
[+]
Isocaloric coconut oil enriched Mediterranean diet seems to improve cognitive functions in patients with Alzheimer's disease.
Jul 19, 2018
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 Jul 20. Epub 2018 Jul 20. PMID:
30056419
Article Published Date
: Jul 19, 2018
Study Type
: Human Study
Additional Links
Substances
:
Coconut Oil
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Neuroprotective Agents
[+]
Kefir improves cognitive deficits.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2020 ;2020:2638703. Epub 2020 Jan 13. PMID:
32411323
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Kefir
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Long-term mindfulness practice may be associated with cognitive and functional improvements for older adults with mild cognitive impairment.
Dec 01, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Alzheimers Dis Rep. 2017 Dec 2 ;1(1):181-193. Epub 2017 Dec 2. PMID:
30480237
Article Published Date
: Dec 01, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Anxiety
,
Cognitive Decline/Dysfunction
,
Dementia
,
Depression
Therapeutic Actions
:
Mindfullness Training
Pharmacological Actions
:
Neuroprotective Agents
[+]
Maintaining higher concentrations of lutein in respect to plasma lipids may moderately decrease the risk of dementia and Alzheimer's disease.
Aug 17, 2015
Click here to read the entire abstract
Pubmed Data
: J Gerontol A Biol Sci Med Sci. 2015 Aug 18. Epub 2015 Aug 18. PMID:
26286605
Article Published Date
: Aug 17, 2015
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids
,
Lutein
Diseases
:
Alzheimer's Disease
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Meditation or music can enhance both subjective memory function and objective cognitive performance in adults with subjective cognitive decline.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2017 ;56(3):899-916. PMID:
28106552
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Therapeutic Actions
:
Meditation
,
Music
[+]
Medium Chain Triglycerides (coconut fat) increase cognitive performance in Alzheimer's disease.
Mar 22, 2006
Click here to read the entire abstract
Pubmed Data
:
Neurobiol Aging.
2004 Mar;25(3):311-4. PMID:
15123336
Article Published Date
: Mar 22, 2006
Study Type
: Human Study
Additional Links
Substances
:
Coconut
,
Coconut Oil
,
Medium Chain Triglycerides
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
[+]
Melissa officinalis extract has a therapeutic effect on patients with mild to moderate Alzheimer's disease.
Jul 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Neurol Neurosurg Psychiatry. 2003 Jul;74(7):863-6. PMID:
12810768
Article Published Date
: Jul 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Melissa (Lemonbalm)
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Plant Extracts
[+]
Memantine does not improve significant agitation in people with in moderate-to-severe AD.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2012 ;7(5):e35185. Epub 2012 May 2. PMID:
22567095
Article Published Date
: Jan 01, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Null Finding
Problem Substances
:
Memantine
[+]
Moderate intensity of aerobic exercise can improve cognitive function in patients with mild Alzheimer's disease.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: CNS Neurol Disord Drug Targets. 2015 ;14(10):1292-7. PMID:
26556080
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Therapeutic Actions
:
Exercise: Aerobic
,
Exercise: Cycling
[+]
Music therapy has a positive effect in treating anxiety and depression in patients suffering from Alzheimer's disease.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Encephale. 2009 Feb;35(1):57-65. Epub 2008 Feb 20. PMID:
19250995
Article Published Date
: Feb 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Music
[+]
Music therapy improved some cognitive, psychological, and behavioural alterations in patients with Alzheimer disease.
Feb 16, 2016
Click here to read the entire abstract
Pubmed Data
: Neurologia. 2016 Feb 17. Epub 2016 Feb 17. PMID:
26896913
Article Published Date
: Feb 16, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Music
[+]
Omega-3 FA intake combined with aerobic exercise and cognitive stimulation prevents atrophy in AD-related brain regions in MCI patients.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Neuroimage. 2016 May 1 ;131:226-38. Epub 2015 Oct 1. PMID:
26433119
Article Published Date
: Apr 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Therapeutic Actions
:
Exercise: Aerobic
,
Integrative Medicine
Pharmacological Actions
:
Neuroprotective Agents
[+]
Oxidative stress and inflammation are associated with physical frailty in patients with Alzheimer's disease.
Jun 13, 2016
Click here to read the entire abstract
Pubmed Data
: Geriatr Gerontol Int. 2016 Jun 14. Epub 2016 Jun 14. PMID:
27296166
Article Published Date
: Jun 13, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Inflammation
,
Oxidative Stress
[+]
Participants randomized to the probiotic group will show greater improvements in psychological status compared to participants in the placebo group.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Contemp Clin Trials Commun. 2018 Dec ;12:192-197. Epub 2018 Nov 14. PMID:
30511028
Article Published Date
: Nov 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease.
Nov 19, 2019
Click here to read the entire abstract
Pubmed Data
: Brain. 2019 Nov 20. Epub 2019 Nov 20. PMID:
31746986
Article Published Date
: Nov 19, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Air Pollution Linked Toxicity
,
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
[+]
Periodontitis was associated with an increase in cognitive decline in Alzheimer’s Disease.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(3):e0151081. Epub 2016 Mar 10. PMID:
26963387
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Periodontitis
Additional Keywords
:
Increased Risk
[+]
Peripheral chronic low-grade inflammation in participants with ApoE4 was associated with shortened latency for onset of Alzheimer’s disease.
Oct 04, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: JAMA Netw Open. 2018 Oct 5 ;1(6):e183597. Epub 2018 Oct 5. PMID:
30646251
Article Published Date
: Oct 04, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
C-Reactive Protein
,
Inflammation
Additional Keywords
:
Risk Factors
[+]
Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias.
Dec 15, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neurol Neurosurg Psychiatry. 2017 Dec 16. Epub 2017 Dec 16. PMID:
29248892
Article Published Date
: Dec 15, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Dementia: Lewy Body
Additional Keywords
:
Alzheimer's disease
,
Brain Inflammation
,
Dementia: Lewy Body
[+]
Phosphatidylserine has a therapeutic effect in Alzheimer's disease.
Jan 01, 1992
Click here to read the entire abstract
Pubmed Data
: Psychopharmacol Bull. 1992;28(1):61-6. PMID:
1609044
Article Published Date
: Jan 01, 1992
Study Type
: Human Study
Additional Links
Substances
:
Phosphatidylserine
Diseases
:
Alzheimer's Disease
[+]
Photobiomodulation shows potential for home treatment of patients with dementia and Alzheimer's disease.
Feb 09, 2017
Click here to read the entire abstract
Pubmed Data
: Photomed Laser Surg. 2017 Feb 10. Epub 2017 Feb 10. PMID:
28186867
Article Published Date
: Feb 09, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Dementia
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
[+]
Physical activity reduces the long-term risk of dementia, especially Alzheimer's disease.
Feb 29, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Epidemiol. 2016 Mar ;31(3):267-74. Epub 2016 Feb 8. PMID:
26857126
Article Published Date
: Feb 29, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Dementia
Therapeutic Actions
:
Exercise
Additional Keywords
:
Risk Reduction
[+]
Polymicrobial infections in brain tissue from Alzheimer’s disease patients.
Jan 16, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 07 17 ;7(1):5559. Epub 2017 Jul 17. PMID:
28717130
Article Published Date
: Jan 16, 2017
Study Type
: Human In Vitro, Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Bacterial Infections
,
Fungus Diseases
[+]
Practice of simple mind-body therapies may alter plasma Aβ levels, telomere length, and telomerase activity.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 ;66(3):947-970. PMID:
30320574
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Meditation
,
Music
Additional Keywords
:
Risk Reduction
[+]
Probiotic and selenium co-supplementation for 12 weeks to patients with Alzheimer's disease improved cognitive function and some metabolic profiles.
Dec 09, 2018
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2018 Dec 10. Epub 2018 Dec 10. PMID:
30642737
Article Published Date
: Dec 09, 2018
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
,
Selenium
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Proton-pump inhibitor use is associated with a broad spectrum of neurological adverse events including impaired hearing, vision, and memory.
Nov 20, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2019 Nov 21 ;9(1):17280. Epub 2019 Nov 21. PMID:
31754136
Article Published Date
: Nov 20, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Dementia
,
Memory Disorders: Drug-Induced
Additional Keywords
:
Increased Risk
Problem Substances
:
Proton-Pump Inhibitors
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Regular exercise may be an especially beneficial intervention to counteract cortical atrophy in all risk groups.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Neuropsychol Soc. 2015 Nov ;21(10):757-67. PMID:
26581788
Article Published Date
: Oct 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Therapeutic Actions
:
Exercise
Additional Keywords
:
Risk Reduction
[+]
Regular exercise may slow the rate of functional deterioration in mild AD and reduce falls in patients suffering from advanced AD.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Dement Geriatr Cogn Disord. 2016 ;41(3-4):233-41. Epub 2016 May 10. PMID:
27160164
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Exercise
Additional Keywords
:
Risk Reduction
[+]
Saffron compares favorably to donepezil in the treatment of mild-to-moderate Alzhemier's disease.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Psychopharmacology (Berl). 2010 Jan;207(4):637-43. Epub 2009 Oct 20. PMID:
19838862
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Saffron
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Sage (Salvia officinalis) extract has a therapeutic effect on patients with mild to moderate Alzheimer's disease.
Feb 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Clin Pharm Ther. 2003 Feb;28(1):53-9. PMID:
12605619
Article Published Date
: Feb 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Sage
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Plant Extracts
[+]
Sea cucumber improves thyroid and cognitive function in patients with Alzheimer's disease.
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Feb;27(2):110-3. PMID:
17342994
Article Published Date
: Feb 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Sea Cucumber
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
[+]
Selective accumulation of aluminum in cerebral arteries in Alzheimer's disease.
Aug 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inorg Biochem. 2013 Sep ;126:35-7. Epub 2013 May 21. PMID:
23764827
Article Published Date
: Aug 31, 2013
Study Type
: Human Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
Problem Substances
:
Aluminum
[+]
Serum lycopene, lutein and zeaxanthin, and the risk of Alzheimer's disease mortality in older adults.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Dement Geriatr Cogn Disord. 2014 ;37(3-4):246-56. Epub 2013 Nov 15. PMID:
24247062
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids
,
Lutein
,
Lycopene
,
Tomato
,
Zeaxanthin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Serum Vitamin D deficiency was associated with mild cognitive impairment and dementia.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Rev Invest Clin. 2019 ;71(6):381-386. PMID:
31823966
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
,
Vitamin D Deficiency
Additional Keywords
:
Risk Factors
[+]
Silicic acid may reduce the body burden of aluminium in Alzheimer's patients.
Dec 01, 2006
Click here to read the entire abstract
Pubmed Data
: Am J Obstet Gynecol. 2006 Dec;195(6):1693-9. Epub 2006 Jun 21. PMID:
16988476
Article Published Date
: Dec 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Silica
,
Silica: Orthosilicic acid
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
Pharmacological Actions
:
Detoxifier
[+]
Spontaneous low frequency BOLD signal variations from resting-state fMRI are decreased in Alzheimer disease.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(6):e0178529. Epub 2017 Jun 5. PMID:
28582450
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
[+]
Statin-associated adverse cognitive effects have been reported with 90% resolving after drug discontinuation.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2009 Jul ;29(7):800-11. PMID:
19558254
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
,
Memory Disorders
,
Memory Loss
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Sunlight exposure ameliorates osteoporosis and vitamin D deficiency in hospitalized, elderly women with Alzheimer's disease.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: J Bone Miner Res. 2005 Aug;20(8):1327-33. Epub 2005 Apr 4. PMID:
16007329
Article Published Date
: Aug 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Elderly: Age Specific Diseases
,
Osteoporosis
Therapeutic Actions
:
Sunlight exposure
[+]
The degree of pineal gland calcification is significantly higher in Alzhemier's disease patients vs. other types of dementia.
Feb 01, 2008
Click here to read the entire abstract
Pubmed Data
: Neurobiol Aging. 2008 Feb;29(2):203-9. Epub 2006 Nov 13. PMID:
17097768
Article Published Date
: Feb 01, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Pineal Gland Calcification
Additional Keywords
:
Diseases that are Linked
[+]
The effect of electroacupuncture on improving mini-mental state examination in patients with Alzheimer's disease is similar to donepezil.
Jan 11, 2019
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhen Jiu. 2019 Jan 12 ;39(1):3-8. PMID:
30672248
Article Published Date
: Jan 11, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Neuroprotective Agents
[+]
The Mediterranean diet is associated with a lower Alzheimer disease mortality.
Sep 11, 2007
Click here to read the entire abstract
Pubmed Data
: Neurology. 2007 Sep 11 ;69(11):1084-93. PMID:
17846408
Article Published Date
: Sep 11, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
[+]
The present study showed the potential use of integrated yoga intervention in reducing stress, anxiety, and depression.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Adv Mind Body Med. 2018 Summer;32(3):18-22. PMID:
31370033
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Yoga
Pharmacological Actions
:
Anti-Anxiety Agents
,
Antidepressive Agents
[+]
The prevalence of cognitive impairment and depressed mood decreased with increases in physiological melatonin levels in this study.
Jun 07, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Endocrinol Metab. 2015 Jun 8:jc20151859. Epub 2015 Jun 8. PMID:
26052727
Article Published Date
: Jun 07, 2015
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Depressive Disorder
Pharmacological Actions
:
Antidepressive Agents
,
Neuroprotective Agents
[+]
The spice sage and its active, neuroprotective ingredient rosmarinic acid could validate the traditional use of this spice in the treatment of Alzheimer's disease.
Jun 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Exp Ther. 2006 Jun;317(3):1143-9. Epub 2006 Feb 22. PMID:
16495207
Article Published Date
: Jun 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Sage
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Confirm
[+]
The study design proved a simple cost effective trial protocol to test the efficacy of herbal medicines on verbal episodic memory.
Jan 14, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 Jan 15 ;39:42-48. Epub 2017 Aug 18. PMID:
29433682
Article Published Date
: Jan 14, 2018
Study Type
: Human Study
Additional Links
Substances
:
Lemon Balm
,
Rosemary
,
Sage
Diseases
:
Alzheimer's Disease
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
,
Risk Reduction
[+]
Therapeutic touch educes agitated behavior and cortisol in persons with Alzheimer's disease.
Oct 01, 2002
Click here to read the entire abstract
Pubmed Data
: Biol Res Nurs. 2002 Oct;4(2):104-14. PMID:
12408216
Article Published Date
: Oct 01, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
High Cortisol
Therapeutic Actions
:
Massage/Therapeutic Touch
[+]
These findings suggest that exercise might play an important role in the prevention of Alzheimer's disease.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Neuropsychol Soc. 2015 Nov ;21(10):841-50. PMID:
26581795
Article Published Date
: Oct 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Exercise
Additional Keywords
:
Risk Reduction
[+]
These findings suggest that ionizing radiation is a risk factor for Alzheimer's disease.
Jun 21, 2017
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2017 Jun 22. Epub 2017 Jun 22. PMID:
28671130
Article Published Date
: Jun 21, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Risk Factors
Anti Therapeutic Actions
:
Low Dose Ionizing Radiation
Problem Substances
:
Radon
[+]
These results suggest that altered circulating levels of common metabolic risk factors lead to the co-existence of depression with AD in many patients.
Apr 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging Dis. 2017 May ;8(3):267-276. Epub 2017 May 2. PMID:
28580183
Article Published Date
: Apr 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Inflammation
,
Vitamin D Deficiency
[+]
This study found that exosomal transcription factors were diminished 2-10 years before clinical diagnosis of Alzheimer's disease.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Clin Transl Neurol. 2015 Jul ;2(7):769-73. Epub 2015 May 13. PMID:
26273689
Article Published Date
: Jun 30, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Exosomes
[+]
Vitamin B12 deficiency may be implicated in Alzehimer's disease.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2010;19(2):481-8. PMID:
20110595
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-12
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Interleukin-6 upregulation
[+]
Vitamin D deficiency might pose a greater risk for ApoEɛ4 non-carrier Alzheimer's disease patients.
Jun 28, 2016
Click here to read the entire abstract
Pubmed Data
: Neurol Sci. 2016 Jun 29. Epub 2016 Jun 29. PMID:
27357856
Article Published Date
: Jun 28, 2016
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
,
Vitamin D Deficiency
Additional Keywords
:
Risk Factors
[+]
Vitamin D was associated with delayed onset of psychotic symptoms in patients with Alzheimer's disease.
Mar 26, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Geriatr Psychiatry. 2019 Mar 27. Epub 2019 Mar 27. PMID:
31126722
Article Published Date
: Mar 26, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Vitamin D3 and curcuminoids (turmeric) stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2009 Jul;17(3):703-17. PMID:
19433889
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Vitamin D
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Disease Regression
[+]
Vitamin E and Alzheimer's disease: the mediating role of cellular aging.
May 02, 2019
Click here to read the entire abstract
Pubmed Data
: Aging Clin Exp Res. 2019 May 3. Epub 2019 May 3. PMID:
31054115
Article Published Date
: May 02, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Vitamin E use is associated with improved survival in an Alzheimer's disease cohort.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Dement Geriatr Cogn Disord. 2009;28(6):536-40. Epub 2009 Dec 10. PMID:
20016184
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Alzheimer's Disease
[+]
Vitamin supplementation leads to reduced levels of carbonyl proteins in patients.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Neurodegener Dis. 2016 ;16(3-4):284-9. Epub 2015 Nov 21. PMID:
26587902
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
,
Thiamine (B-1)
,
Vitamin B-12
,
Vitamin B-6
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Working night or evening shifts was associated with a significant increase in all-cause mortality when compared to working day shift.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Scand J Work Environ Health. 2017 Mar 1 ;43(2):117-126. PMID:
28245504
Article Published Date
: Feb 28, 2017
Study Type
: Human Study
Additional Links
Diseases
:
All-Cause Mortality
,
Alzheimer's Disease
,
Dementia
Additional Keywords
:
Risk Factors
Anti Therapeutic Actions
:
Shift Work
[+]
Administration of O. sanctum ethanolic extract may stimulate and restore the expression of choline acetyltransferase on the deteriorating cells of HCMECs.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Vet World. 2016 Dec ;9(12):1348-1354. Epub 2016 Dec 3. PMID:
28096604
Article Published Date
: Nov 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Holy Basil
Diseases
:
Alzheimer's Disease
,
Dementia
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Bromelain degrades Aβ1-42 monomers and soluble aggregates.
Jan 22, 2018
Click here to read the entire abstract
Pubmed Data
: Curr Alzheimer Res. 2018 Jan 23. Epub 2018 Jan 23. PMID:
29359669
Article Published Date
: Jan 22, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Bromelain
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin inhibits Aβ-induced neuronal damage and cell death involving the prevention from intracellular Ca2+ elevation mediated by the NMDA receptor.
Jun 07, 2015
Click here to read the entire abstract
Pubmed Data
: J Recept Signal Transduct Res. 2015 Jun 8:1-8. Epub 2015 Jun 8. PMID:
26053510
Article Published Date
: Jun 07, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Dose Response
[+]
Findings from in vivo and in vitro studies provide further support for the protective effect of Oleocanthal against the progression of Alzheimer's Disease.
Sep 15, 2015
Click here to read the entire abstract
Pubmed Data
: ACS Chem Neurosci. 2015 Sep 16. Epub 2015 Sep 16. PMID:
26348065
Article Published Date
: Sep 15, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Oleocanthal
,
Olive Oil
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Germinated brown rice alters Aβ(1-42) aggregation and modulates Alzheimer's disease-related genes.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:153684. Epub 2015 Dec 22. PMID:
26858770
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Brown Rice: Pre-Germinated
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Nobiletin appears to be a promising novel prophylactic seed drug or functional food for Alzheimer's disease.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2018 ;41(4):451-457. PMID:
29607920
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Nobiletin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
,
Prophylactic Agents
Additional Keywords
:
Alzheimer's disease
,
Neuroprotective Agents
,
Nobiletin
,
Prophylactic Agents
[+]
Oligonol has strong preventative potential in diabetes mellitus and in Alzheimer's disease.
Feb 29, 2016
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2016 Mar ;39(3):409-20. Epub 2016 Jan 2. PMID:
26724817
Article Published Date
: Feb 29, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Lychee
Diseases
:
Alzheimer's Disease
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
,
Alpha-glucosidase inhibitor
Additional Keywords
:
Dose Response
,
Proanthocyanidins
[+]
Several widely used triazines enhance the production of toxic, aggregation prone Aβ42/Aβ43 amyloids.
Oct 17, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2016 Oct 18 ;54(4):1593-1605. PMID:
27589520
Article Published Date
: Oct 17, 2016
Study Type
: Human In Vitro
Additional Links
Diseases
:
Alzheimer's Disease
,
Herbicide Toxicity
Additional Keywords
:
Increased Risk
Problem Substances
:
Herbicides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect.
Mar 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2018 Mar 12 ;15(1):75. Epub 2018 Mar 12. PMID:
29530050
Article Published Date
: Mar 11, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
These findings support resveratrol as a candidate for inducing resilience and protection against Alzheimer's disease.
Jul 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Jul 31 ;11(8). Epub 2019 Jul 31. PMID:
31370365
Article Published Date
: Jul 30, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
This demonstrates the broad neuroprotective action of apigenin against AD pathogenesis in a human disease model.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:31450. Epub 2016 Aug 12. PMID:
27514990
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
This study found that inflammatory response was a very important mechanism in two diseases of opposite phenotypes, that is, cancer (cell survival) and Alzheimer's disease (cell death).
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2015 ;2015:205247. Epub 2015 Jul 26. PMID:
26273596
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Diseases
:
Alzheimer's Disease
,
Cancers: All
,
Inflammation
Additional Keywords
:
Diseases that are Linked
[+]
Thymoquinone holds a neuroprotective potential and could be a promising therapeutic agent to reduce the risk of developing Alzheimer's disease.
Feb 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biochem Biophys Rep. 2019 Mar ;17:122-126. Epub 2019 Jan 3. PMID:
30623116
Article Published Date
: Feb 28, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Thymoquinone
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Caprylic triglyceride impove certain cases of mild-to-moderate Alzheimer's disease.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Article Published Date
: Dec 31, 2012
Study Type
: Human: Case Report
Additional Links
Substances
:
Caprylic Acid
,
Coconut Oil
,
Medium Chain Triglycerides
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
[+]
Ketogenic diet rescues cognition in ApoE4+ patient with mild Alzheimer's disease: A case study.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Diabetes Metab Syndr. 2019 Mar - Apr;13(2):1187-1191. Epub 2019 Jan 24. PMID:
31336463
Article Published Date
: Mar 31, 2019
Study Type
: Human: Case Report
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions
:
Neuroprotective Agents
[+]
This case report described a man whose occupational exposure to aluminum suggests a role for aluminum in disease aetiology.
Feb 10, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Case Rep. 2014 Feb 10 ;8:41. Epub 2014 Feb 10. PMID:
24513181
Article Published Date
: Feb 10, 2014
Study Type
: Human: Case Report
Additional Links
Diseases
:
Alzheimer's Disease
Problem Substances
:
Aluminum
[+]
Transcranial LED therapy increased the cerebral blood flow in an elderly women.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Lasers Med Sci. 2015 Jan ;30(1):339-46. Epub 2014 Oct 3. PMID:
25277249
Article Published Date
: Dec 31, 2014
Study Type
: Human: Case Report
Additional Links
Diseases
:
Alzheimer's Disease
,
Dementia
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Additional Keywords
:
Significant Treatment Outcome
[+]
Turmeric has a beneficial effecct on Alzheimer's disease with behavioral and psychological symptoms of dementia.
Sep 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ayu. 2012 Oct ;33(4):499-504. PMID:
23723666
Article Published Date
: Sep 30, 2012
Study Type
: Human: Case Report
Additional Links
Diseases
:
Alzheimer's Disease
[+]
Two cases of suicide in patients with a diagnosis of probable Alzheimer disease and who were treated with cholinesterase inhibitor drugs have been reported.
Apr 01, 1999
Click here to read the entire abstract
Pubmed Data
: Alzheimer Dis Assoc Disord. 1999 Apr-Jun;13(2):88-90. PMID:
10372951
Article Published Date
: Apr 01, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Alzheimer's Disease
Problem Substances
:
Cholinesterase Inhibitor Drugs
,
Eptastigmine
[+]
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside may be beneficial for Alzheimer's disease prevention and treatment.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2018 01 1 ;495(1):672-678. Epub 2017 Nov 9. PMID:
29129695
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
6-gingerol may be useful in the prevention and treatment of alzheimer's disease.
Mar 25, 2015
Click here to read the entire abstract
Pubmed Data
: Rejuvenation Res. 2015 Mar 26. Epub 2015 Mar 26. PMID:
25811848
Article Published Date
: Mar 25, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Gingerol
Diseases
:
Alzheimer's Disease
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
Additional Keywords
:
Plant Extracts
[+]
A combination of ginger and peony root may prevent memory impairment in AD by inhibiting Aβ accumulation and inflammation in the brain.
Nov 29, 2015
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2015 Nov 30. Epub 2015 Nov 30. PMID:
26639976
Article Published Date
: Nov 29, 2015
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ginger
,
Peony
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
[+]
A combination of lycopene and vitamin E acted in a synergistic fashion to bring significant effects against oxidative stress in tauopathies.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2017 ;57(2):475-482. PMID:
28269786
Article Published Date
: Dec 31, 2016
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Lycopene
,
Vitamin E
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Natural Substance Synergy
[+]
A combination of nutrients improves cognitive functioning while decreasing Alzheimer disease neuropathology in an animal model.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(11):e14015. Epub 2010 Nov 17. PMID:
21103342
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
,
B-complex
,
Curcumin
,
EGCG (Epigallocatechin gallate)
,
Folic Acid
,
NAC (N-acetyl-L-cysteine)
,
Piperine
,
Vitamin C
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
A combined plant extract WS-5 could be applied as a natural product therapy with a focus on neuroinflammation-related neurodegenerative disorders.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:5160293. Epub 2019 Apr 1. PMID:
31057649
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Turmeric
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
,
Neuroprotective Agents
[+]
A diet containing a mixture of P. montana and red ginseng extracts reversed learning and memory impairments.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Sci Biotechnol. 2018 Aug ;27(4):1193-1200. Epub 2018 Apr 4. PMID:
30263850
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Kudzu
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
,
Neuroprotective Agents
Additional Keywords
:
Natural Substance Synergy
[+]
A flavonoid-rich extract from Diospyros kaki may be a potential therapeutic strategy for preventing and treating Alzheimer's disease.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2018 Jan 1 ;1678:85-93. Epub 2017 Oct 14. PMID:
29038004
Article Published Date
: Dec 31, 2017
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Persimmon
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
A high‐fat diet can significantly promote the progression of Alzheimer's disease like pathology.
Jun 12, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Am Heart Assoc. 2016 Jun 13 ;5(6). Epub 2016 Jun 13. PMID:
27412896
Article Published Date
: Jun 12, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
High Fat Diet
Additional Keywords
:
Risk Factors
[+]
A jujube extract can reduce Aβ-induced toxicity in Caenorhabditis elegans.
Jul 14, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Jul 15 ;239:111886. Epub 2019 Apr 23. PMID:
31026552
Article Published Date
: Jul 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Jujube
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
A methanolic extract of Piper nigrum ameliorates beta-amyloid (1–42)-induced anxiety and depression by attenuation of the oxidative stress in the rat amygdala.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Behav Brain Funct. 2015 ;11:13. Epub 2015 Mar 29. PMID:
25880991
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Black Pepper
Diseases
:
Alzheimer's Disease
,
Anxiety Disorders
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Anxiolytic
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
A nanoformulation of pomegranate seed oil can delay disease onset in a mouse model of genetic prion diseases.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nanomedicine. 2014 Aug ;10(6):1353-63. Epub 2014 Apr 2. PMID:
24704590
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Alzheimer's Disease
,
Creutzfeldt-Jakob disease
,
Lipid Peroxidation
,
Neurodegenerative Diseases
,
Prion Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
A walnut-enriched diet may help reduce the risk or delay the onset and progression of Alzheimer's disease.
Jul 16, 2018
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 Jul 17. Epub 2018 Jul 17. PMID:
30040727
Article Published Date
: Jul 16, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Walnut
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Accelerative effects of carbazole-type alkaloids from Murraya koenigii on neurite outgrowth and their derivative's in vivo study for spatial memory.
Jan 19, 2020
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2020 Jan 20. Epub 2020 Jan 20. PMID:
31960209
Article Published Date
: Jan 19, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Curry Tree
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuritogenic
,
Neuroprotective Agents
[+]
Acetyl-11-keto-β-boswellic acid ameliorates cognitive deficits and reduces amyloid-β levels.
Mar 31, 2020
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2020 Apr ;150:96-108. Epub 2020 Feb 25. PMID:
32109514
Article Published Date
: Mar 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Acupuncture plus moxibustion intervention can improve the learning-memory ability in Alzheimer's disease rats.
Feb 24, 2019
Click here to read the entire abstract
Pubmed Data
: Zhen Ci Yan Jiu. 2019 Feb 25 ;44(2):79-84. PMID:
30945481
Article Published Date
: Feb 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moxibustion
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Acupuncture
Pharmacological Actions
:
Neuroprotective Agents
[+]
Acute formaldehyde exposure induced early Alzheimer-like changes in mouse brain.
Aug 15, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Mech Methods. 2017 Aug 16:1-30. Epub 2017 Aug 16. PMID:
28812438
Article Published Date
: Aug 15, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Formaldehyde Toxicity
Additional Keywords
:
Risk Factors
Problem Substances
:
Formaldehyde
[+]
Administration of Berberis vulgaris could ameliorate neurotoxicity induced by beta amyloid.
Jul 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Jul 5 ;758:82-8. Epub 2015 Apr 8. PMID:
25861937
Article Published Date
: Jul 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Barberry
,
Berberine
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Administration of pomegranate peel extract has neuroprotective effects involving multiple mechanisms.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(11):e0166123. Epub 2016 Nov 9. PMID:
27829013
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Alzheimer's Disease
,
Lipid Peroxidation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Aegle marmelos leaf extract ameliorates the cognitive impairment and oxidative stress.
Feb 12, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Feb 13. Epub 2019 Feb 13. PMID:
30771313
Article Published Date
: Feb 12, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Alzheimer's Disease
,
Diabetes: Cognitive Dysfunction
,
Diabetes: Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alcohol extracts from Ganoderma lucidum delay the progress of Alzheimer's disease.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:272. Epub 2019 Mar 26. PMID:
30971923
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
DNA Methylation
[+]
Allicin ameliorates cognitive impairment in APP/PS1 mice.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: Tissue Cell. 2018 Feb ;50:89-95. Epub 2017 Dec 2. PMID:
29429523
Article Published Date
: Jan 31, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Alpha-linolenic acid might be a potential candidate for prevention or treatment of neurodegenerative diseases such as Alzheimer's disease.
Dec 12, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Dec 13 ;65(49):10719-10729. Epub 2017 Nov 28. PMID:
29092397
Article Published Date
: Dec 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Aluminium may cause severe motor neuron damage in rat spinal cord resembling amyotrophic lateral sclerosis.
Mar 31, 1999
Click here to read the entire abstract
Pubmed Data
: Acta Histochem. 1999 Apr ;101(2):193-201. PMID:
10335362
Article Published Date
: Mar 31, 1999
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
,
Amyotrophic lateral sclerosis (ALS)
,
Motor Neuron Disease
Additional Keywords
:
aluminum
,
aluminum toxicity
,
Alzheimer's disease
,
Amyotrophic lateral sclerosis (ALS)
,
Motor Neuron Disease
Problem Substances
:
Aluminum
[+]
Alzheimer's disease histological and behavioral manifestations in the APP/PS1 mice were found to be correlated with a specific gut microbiome state.
Nov 27, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2016 Nov 28. Epub 2016 Nov 28. PMID:
27911317
Article Published Date
: Nov 27, 2016
Study Type
: Transgenic Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Dysbiosis
Additional Keywords
:
Microbiome
[+]
Ameliorating effect of Citrus aurantium extracts and nobiletin on β‑amyloid (1‑42)‑induced memory impairment.
Aug 08, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2019 Aug 9. Epub 2019 Aug 9. PMID:
31432129
Article Published Date
: Aug 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
,
Nobiletin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Angelica gigas can improve cognitive symptoms in mild cognitive impairment model mice.
Dec 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Dec 30 ;12(1). Epub 2019 Dec 30. PMID:
31905851
Article Published Date
: Dec 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Angelica
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Angelica sinensis prevents neurotoxicity induced by Abeta-associated oxidative stress.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2008 Sep;15(9):710-21. Epub 2008 Apr 29. PMID:
18448320
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Angelica
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.
Nov 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Nov 28 ;18(12). Epub 2017 Nov 28. PMID:
29182579
Article Published Date
: Nov 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
[+]
Anti-amnesic activity of Citrus aurantium flowers extract against scopolamine-induced memory impairments in rats.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Neurol Sci. 2015 Apr ;36(4):553-60. Epub 2014 Nov 4. PMID:
25367404
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
Diseases
:
Alzheimer's Disease
,
Memory Disorders: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Anti-neuroinflammatory effects of a food-grade phenolic-enriched maple syrup extract in a mouse model of Alzheimer's disease.
Oct 03, 2019
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2019 Oct 4:1-10. Epub 2019 Oct 4. PMID:
31583972
Article Published Date
: Oct 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Maple Syrup
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
[+]
Antibiotic use induced perturbations in the microbial diversity during post-natal development of animals which altered amyloid pathologies.
Sep 04, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Sep 5 ;7(1):10411. Epub 2017 Sep 5. PMID:
28874832
Article Published Date
: Sep 04, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Antibiotic Toxicity
Problem Substances
:
Antibiotics
[+]
Antroquinonol could have beneficial effects on Alzheimer’s disease like deficits in APP transgenic mouse.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2015 ;5:15067. Epub 2015 Oct 15. PMID:
26469245
Article Published Date
: Dec 31, 2014
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Antrodia camphorata
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
NF-E2-Related Factor-2 (Nrf2) Modulator
[+]
Ascorbic acid ameliorates behavioural deficits and neuropathological alterations in rat model of Alzheimer's disease.
Feb 05, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2017 Feb 6 ;50:200-211. Epub 2017 Feb 6. PMID:
28192749
Article Published Date
: Feb 05, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
,
Antioxidants
,
Neuroprotective Agents
[+]
Ashwaganda contains compounds which may amerliorate neuronal dysfunction in Alzheimer's disease.
Mar 01, 2006
Click here to read the entire abstract
Pubmed Data
: Eur J Neurosci. 2006 Mar;23(6):1417-26. PMID:
16553605
Article Published Date
: Mar 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Ashwagandha
Diseases
:
Alzheimer's Disease
[+]
Ashwaganda reverses some aspects of Alzheimer's disease pathology.
Jan 30, 2012
Click here to read the entire abstract
Pubmed Data
: Proc Natl Acad Sci U S A. 2012 Jan 30. Epub 2012 Jan 30. PMID:
22308347
Article Published Date
: Jan 30, 2012
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ashwagandha
Diseases
:
Alzheimer's Disease
[+]
Asiatic acid could be able to modulate various pathological features of Alzheimer's disease and could hold promise in its treatment.
Jan 21, 2019
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2019 Jan 22. Epub 2019 Jan 22. PMID:
30671870
Article Published Date
: Jan 21, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Problem Substances
:
Aluminum Chloride
[+]
Astaxanthin and docosahexaenoic acid might be a potential therapeutic combination for Alzheimer's disease.
Apr 24, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Apr 25. Epub 2018 Apr 25. PMID:
29695154
Article Published Date
: Apr 24, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Astaxanthin
,
DHA (Docosahexaenoic Acid)
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Astaxanthin as a potential treatment to slow the onset or progression of cognitive dysfunctions.
Dec 11, 2018
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2018 Dec 12. Epub 2018 Dec 12. PMID:
30552898
Article Published Date
: Dec 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Alzheimer's Disease
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Astaxanthin may be useful for the treatment of neurodegenerative disorders such as Alzheimer's disease.
Sep 09, 2015
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2015 Sep 10 ;303:558-68. Epub 2015 Jul 18. PMID:
26197224
Article Published Date
: Sep 09, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Astragaloside might be a useful chemical in improving the spatial memory and relieving the oxidative stress and neuroinflammation in Alzheimer patients.
Mar 29, 2018
Click here to read the entire abstract
Pubmed Data
: Chin Med Sci J. 2018 Mar 30 ;33(1):29-37. PMID:
29620512
Article Published Date
: Mar 29, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
At seeming safe concentrations, synergistic effects of PM2.5 and formaldehyde co-exposure induces Alzheimer-like changes in mouse brain.
Nov 16, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Nov 17 ;8(58):98567-98579. Epub 2017 Oct 6. PMID:
29228711
Article Published Date
: Nov 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Air Pollution Linked Toxicity
,
Alzheimer's Disease
,
Formaldehyde Toxicity
Additional Keywords
:
Synergistic Toxicity
Problem Substances
:
Formaldehyde
[+]
B. breve A1 has therapeutic potential for preventing cognitive impairment in Alzheimer's disease.
Oct 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Oct 18 ;7(1):13510. Epub 2017 Oct 18. PMID:
29044140
Article Published Date
: Oct 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bifidobacterium Breve
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Bacopa enhances cognitive function and protects against neurodegeneration in an Alzheimer's disease model.
Oct 04, 2009
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2009 Oct 4. Epub 2009 Oct 4. PMID:
19808086
Article Published Date
: Oct 04, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Neurodegenerative Diseases
[+]
Bacopa extract reduces brain amyloid levels in mice by as much as 60%.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2006 Aug;9(3):243-51. PMID:
16914834
Article Published Date
: Aug 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Aging: Brain
,
Alzheimer's Disease
,
Amyloidosis
Pharmacological Actions
:
Neurorestorative
Additional Keywords
:
Plant Extracts
[+]
Bacopa monnieri extracts have memory enhancing and anti-diabetic properties.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(7):e0131862. Epub 2015 Jul 10. PMID:
26161865
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Diabetes Mellitus: Type 2
,
Memory Loss
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Gene Expression Regulation
[+]
Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action.
Jan 01, 2019
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2019 Jan 2. Epub 2019 Jan 2. PMID:
30604025
Article Published Date
: Jan 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Alzheimer's Disease
,
Dementia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bacopaside I can reduce the beta amyloid levels in the brains of mice in an Alzheimer's disease model.
Mar 01, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging (Albany NY). 2016 Mar 2. Epub 2016 Mar 2. PMID:
26946062
Article Published Date
: Mar 01, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Baicalein significantly improved the biochemical and histopathological condition of Alzheimer's disease in rats.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropsychiatr Dis Treat. 2016 ;12:3145-3152. Epub 2016 Dec 9. PMID:
28003750
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Alzheimer's disease
,
Baicalein
,
Dose Response
,
Neuroprotective Agents
[+]
Bamboo extract inhibits neuronal secretion of Alzheimer's beta-amyloid peptides.
Dec 01, 2003
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2003 Dec;28(12):1785-92. PMID:
14649718
Article Published Date
: Dec 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Bay leaf prevents dopamine-induced neurotoxicity.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2010 Dec;33(12):1953-8. Epub 2010 Dec 30. PMID:
21191760
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bay leaf
Diseases
:
Alzheimer's Disease
,
Dopamine Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Bee venom could be considered a potential therapeutic or preventive agent for PD and other neuroinflammatory associated disorders.
Jul 27, 2016
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2016 Jul 28. Epub 2016 Jul 28. PMID:
27469335
Article Published Date
: Jul 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Bee venom soluble phospholipase A2 exerts neuroprotective effects in a lipopolysaccharide-induced mouse model of Alzheimer's disease.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2019 ;11:287. Epub 2019 Nov 1. PMID:
31736738
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Alzheimer's Disease
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Beneficial effect of diosgenin as a stimulator of NGF on the brain with neuronal damage induced by Aβ-42 accumulation.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lab Anim Res. 2016 Jun ;32(2):105-15. Epub 2016 Jun 24. PMID:
27382379
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
[+]
Berberine alleviates amyloid-beta pathogenesis.
Mar 14, 2019
Click here to read the entire abstract
Pubmed Data
: Curr Mol Med. 2019 Mar 15. Epub 2019 Mar 15. PMID:
30873920
Article Published Date
: Mar 14, 2019
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Berberine alleviates amyloid-beta pathology in the brain of APP/PS1 transgenic mice.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Curr Alzheimer Res. 2018 Jul 1. Epub 2018 Jul 1. PMID:
29962345
Article Published Date
: Jun 30, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Berberine clears Aβ deposit and consequently ameliorates spatial learning memory impairment.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:1003. Epub 2019 Sep 6. PMID:
31551793
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Alzheimer's Disease
,
Diabetes: Cognitive Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Berberine may act as a potential neuroprotective agent.
Oct 12, 2016
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2016 Oct 13 ;57:241-250. Epub 2016 Aug 13. PMID:
27746125
Article Published Date
: Oct 12, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Anxiety Agents
,
Neuroprotective Agents
[+]
Berberine nanoencapsulation attenuates hallmarks of scoplomine induced Alzheimer's-like disease.
Jun 27, 2020
Click here to read the entire abstract
Pubmed Data
: Curr Clin Pharmacol. 2020 Jun 28. Epub 2020 Jun 28. PMID:
32598269
Article Published Date
: Jun 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Gene Expression Regulation
[+]
Beta-sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2020 Jan ;24(1):39-46. Epub 2020 Dec 20. PMID:
31908573
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Beta Sitosterol
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Betulinic acid could have a role in Alzheimer's disease through protecting microcirculation, alleviating inflammation, and up-regulating BDNF expression.
Jan 10, 2018
Click here to read the entire abstract
Pubmed Data
: Microcirculation. 2018 11 ;25(8):e12503. Epub 2018 Oct 8. PMID:
30178892
Article Published Date
: Jan 10, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
[+]
Betulinic acid pretreatment was able to prevent Alzheimer's disease induced neurobehavioral deficits.
Jan 29, 2018
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2018 Jan 30 ;337:99-106. Epub 2017 Oct 3. PMID:
28986104
Article Published Date
: Jan 29, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Bilberry polyphenols divert Aβ aggregation to an alternate, non-toxic form.
Aug 24, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2015 Aug 25. Epub 2015 Aug 25. PMID:
26304685
Article Published Date
: Aug 24, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Bioactive compounds in kimchi improve the cognitive and memory functions impaired by amyloid beta.
Oct 19, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Oct 20 ;10(10). Epub 2018 Oct 20. PMID:
30347786
Article Published Date
: Oct 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Kimchi
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Bioactive compounds of kimchi inhibit apoptosis by attenuating endoplasmic reticulum stress in the brain of amyloid β-injected mice.
May 15, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 May 16 ;66(19):4883-4890. Epub 2018 May 7. PMID:
29706080
Article Published Date
: May 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Kimchi
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Black chokeberry has protective effects against the development of Alzheimer's disease.
Jan 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res Pract. 2018 Feb ;12(1):13-19. Epub 2018 Jan 15. PMID:
29399292
Article Published Date
: Jan 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Prophylactic Agents
[+]
Blueberry treatment was beneficial for the improvement of learning and memory of Alzheimer’s disease.
Dec 29, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2016 Dec 30. Epub 2016 Dec 30. PMID:
28035919
Article Published Date
: Dec 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Both electroacupuncture and Gastrodin can improve the learning-memory ability of Alzheimer's disease.
Mar 24, 2018
Click here to read the entire abstract
Pubmed Data
: Zhen Ci Yan Jiu. 2018 Mar 25 ;43(3):140-5. PMID:
29560628
Article Published Date
: Mar 24, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Neuroprotective Agents
[+]
Brahmi promises to be a novel agent in Alzheimer's disease.
Apr 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Neurosci. 2017 May ;24(2):111-122. Epub 2017 May 12. PMID:
28588366
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Cholinesterase Inhibitors
,
Lipoxygenase Inhibitors
,
Neuroprotective Agents
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Butterbur leaves attenuate memory impairment and neuronal cell damage in amyloid beta-induced Alzheimer’s disease models.
May 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Jun 1 ;19(6). Epub 2018 Jun 1. PMID:
29865187
Article Published Date
: May 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Butterbur
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
C. spinosa has the potential to down regulate inflammation-involved genes in Alzheimer's disease.
Oct 24, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2016 Oct 25:1-8. Epub 2016 Aug 25. PMID:
27778760
Article Published Date
: Oct 24, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Capparis spinosa (caper)
,
Flavonoids
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Gene Expression Regulation
[+]
Caffeic acid phenethyl ester could be considered as a promising neuroprotective agent against progressive neurodegenerative diseases.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging Dis. 2018 Aug ;9(4):605-622. Epub 2018 Aug 1. PMID:
30090650
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Cannabidiol reverses deficits in hippocampal long-term potentiation in a model of Alzheimer's disease.
Mar 23, 2018
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2018 Mar 24. Epub 2018 Mar 24. PMID:
29574668
Article Published Date
: Mar 23, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Carnosine prevents Aβ-induced oxidative stress and inflammation in microglial cells.
Jan 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cells. 2019 Jan 17 ;8(1). Epub 2019 Jan 17. PMID:
30658430
Article Published Date
: Jan 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carnosine
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Cellular and molecular mechanisms underlying the action of ginsenoside Rg1 against Alzheimer's disease.
Dec 24, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2012 Dec 25 ;7(36):2860-6. PMID:
25317137
Article Published Date
: Dec 24, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Centella asiatica attenuated the cognitive deficits in rats by restoring cholinergic function, attenuating oxidative stress.
Mar 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxics. 2019 Mar 30 ;7(2). Epub 2019 Mar 30. PMID:
30935005
Article Published Date
: Mar 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Centella asiatica attenuates hippocampal mitochondrial dysfunction and improves memory and executive function in β-amyloid overexpressing mice.
Jan 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Cell Neurosci. 2018 12 ;93:1-9. Epub 2018 Sep 22. PMID:
30253196
Article Published Date
: Jan 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Alzheimer's Disease
,
Mitochondrial Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Centella Asiatica improves memory and promotes antioxidative signalling in 5XFAD mice.
Dec 07, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2019 Dec 8 ;8(12). Epub 2019 Dec 8. PMID:
31817977
Article Published Date
: Dec 07, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Alzheimer's Disease
,
Memory Disorders
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Centella asiatica protects d-Galactose/AlCl3 mediated Alzheimer's disease.
Apr 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Apr 16 ;20(8). Epub 2019 Apr 16. PMID:
31014012
Article Published Date
: Apr 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Chokeberry extract has potential as a therapeutic agent for the prevention and treatment of neurodegenerative diseases.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2016 ;2016:6145926. Epub 2016 Apr 30. PMID:
27239211
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Alzheimer's Disease
,
Memory Disorders: Drug-Induced
,
Neurodegenerative Diseases
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chronic curcumin ameliorates AD-related cognitive deficits and that upregulated BDNF-ERK signaling in the hippocampus.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(6):e0131525. Epub 2015 Jun 26. PMID:
26114940
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Dose Response
[+]
Chronic exposure to the canola-rich diet resulted in a significant increase in body weight and impairments in their working memory.
Dec 06, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Dec 7 ;7(1):17134. Epub 2017 Dec 7. PMID:
29215028
Article Published Date
: Dec 06, 2017
Study Type
: Transgenic Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Memory Disorders
,
Obesity
Problem Substances
:
Canola Oil
[+]
Chronic T. gondii infection promotes neuroinflammation through cytokine networks and induces pathological progression of Alzheimer's disease.
Aug 10, 2016
Click here to read the entire abstract
Pubmed Data
: J Parasitol. 2016 Aug 11. Epub 2016 Aug 11. PMID:
27513205
Article Published Date
: Aug 10, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Toxoplasma gondii Infection
Additional Keywords
:
Increased Risk
[+]
Chrysin loaded lipid-core nanocapsules ameliorates neurobehavioral alterations induced by β-amyloid 1-42.
Jul 14, 2020
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2020 Jul 15 ;390:112696. Epub 2020 May 15. PMID:
32417280
Article Published Date
: Jul 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2011 ;6(1):e16564. Epub 2011 Jan 28. PMID:
21305046
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cinnamon
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
,
Prophylactic Agents
[+]
Coconut leaf extract metabolites could decrease amyloid-β1-42 aggregation.
Apr 20, 2017
Click here to read the entire abstract
Pubmed Data
: Biomedicines. 2017 Apr 21 ;5(2). Epub 2017 Apr 21. PMID:
28536360
Article Published Date
: Apr 20, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Coconut
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Coenzyme Q10 has therapeutic value as demonstrated in a transgenic animal model of Alzheimer's disease.
Jul 28, 2011
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2011 Jul 28. Epub 2011 Jul 28. PMID:
21799249
Article Published Date
: Jul 28, 2011
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Coenzyme Q10 reduces beta-amyloid plaque in an APP/PS1 transgenic mouse model of Alzheimer's disease.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Mol Neurosci. 2010 May;41(1):110-3. Epub 2009 Oct 16. PMID:
19834824
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2012 Jun ;23(3):241-9. PMID:
22470103
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
,
Thymol
Diseases
:
Alzheimer's Disease
,
Dementia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cholinesterase Inhibitors
[+]
Combination of omega 3 and coenzyme Q10 exerts neuroprotective potential against hypercholesterolemia-induced Alzheimer's-like disease.
Mar 01, 2020
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2020 Mar 2. Epub 2020 Mar 2. PMID:
32124160
Article Published Date
: Mar 01, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
,
Omega-3 Fatty Acids
Diseases
:
Alzheimer's Disease
,
Hypercholesterolemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology.
Jan 21, 2019
Click here to read the entire abstract
Pubmed Data
: J Biol Chem. 2019 02 22 ;294(8):2714-2731. Epub 2018 Dec 18. PMID:
30563837
Article Published Date
: Jan 21, 2019
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Ferulic acid
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Components of star fruit have potential benefit on treating learning and memory deficit in APP/PS1 transgenic Alzheimer's disease mice.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;49(3):1064-1073. Epub 2018 Sep 7. PMID:
30196278
Article Published Date
: Dec 31, 2017
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Star Fruit
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Bcl-2 protein down-regulation
,
Neuroprotective Agents
[+]
Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease.
Jul 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jul 28. Epub 2016 Jul 28. PMID:
27486879
Article Published Date
: Jul 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cordyceps militaris could have the protective role from cognitive impairment and progression of Alzheimer's disease.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Food Sci Biotechnol. 2019 Jun ;28(3):865-872. Epub 2018 Dec 4. PMID:
31093445
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
,
Nitric Oxide Inhibitor
[+]
Cortical tau burden and behavioural dysfunctions in mice exposed to monosodium glutamate in early life.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2019 ;14(8):e0220720. Epub 2019 Aug 14. PMID:
31412065
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Risk Factors
Problem Substances
:
Monosodium Glutamate (MSG)
[+]
Cranberry extract may be useful in the treatment of Alzheimer's disease.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2016 Jun ;14(6):427-33. PMID:
27473960
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cranberry
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Crocetin improves amyloid-β accumulation-induced learning and memory deficit in a Alzheimer's disease model.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Immun Ageing. 2018 ;15:24. Epub 2018 Oct 30. PMID:
30450117
Article Published Date
: Dec 31, 2017
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Crocetin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Crocin can improve the synaptic loss and neuronal death.
Jun 09, 2020
Click here to read the entire abstract
Pubmed Data
: J Chem Neuroanat. 2020 Jun 10:101837. Epub 2020 Jun 10. PMID:
32534024
Article Published Date
: Jun 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Crocin demonstrates good prospects in the treatment of Alzheimer's disease through the oxidative stress associated apoptosis signalling pathway.
Dec 17, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2018 Dec 18. Epub 2018 Dec 18. PMID:
30569175
Article Published Date
: Dec 17, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Crocin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
[+]
Crocin improves cognitive behavior in rats with Alzheimer's disease.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2019 ;2019:9454913. Epub 2019 Aug 26. PMID:
31534969
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Crocin inhibits beta amyloid induced apoptosis, which is possibly associated with its antioxidant properties.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Pharmacol Biochem Behav. 2015 Dec ;139(Pt A):47-58. Epub 2015 Oct 17. PMID:
26484504
Article Published Date
: Nov 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin (from Turmeric) reduces amyloid beta plaque formation in an animal model of Alzheimers disease.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Neurochem Int. 2009 Mar-Apr;54(3-4):199-204. Epub 2008 Nov 30. PMID:
15590663
Article Published Date
: Mar 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
[+]
Curcumin (from Turmeric) reduces oxidative damage and amyloid plaque in a transgenic animal model of Alzheimers.
Nov 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Neurosci. 2001 Nov 1;21(21):8370-7. PMID:
11606625
Article Published Date
: Nov 01, 2001
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
[+]
Curcumin administration suppress acetylcholinesterase gene expression in cadmium treated rats.
May 16, 2017
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2017 May 17. Epub 2017 May 17. PMID:
28527659
Article Published Date
: May 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Cadmium Poisoning
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
Problem Substances
:
Cadmium
[+]
Curcumin ameliorates cognitive deficits and neurodegeneration in a rat model of sporadic dementia of Alzheimer's type (SDAT).
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Eur Neuropsychopharmacol. 2009 Sep;19(9):636-47. Epub 2009 Mar 28. PMID:
19329286
Article Published Date
: Sep 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin and rosemary have anti-Alzheimer's activity.
Mar 15, 2004
Click here to read the entire abstract
Pubmed Data
: J Neurosci Res. 2004 Mar 15;75(6):742-50. PMID:
14994335
Article Published Date
: Mar 15, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Rosemary
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
Curcumin attenuated neurodegeneration in this animal model Alzheimer's disease.
Apr 04, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2016 Apr 5. Epub 2016 Apr 5. PMID:
27060945
Article Published Date
: Apr 04, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2006 Jan;130(1):120-6. PMID:
20622013
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin demonstrates therapeutic properties in an animal model of Alzheimer disease.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Exp Ther. 2008 Jul;326(1):196-208. Epub 2008 Apr 16. PMID:
18417733
Article Published Date
: Jul 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Inflammation
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin downregulates GSK3 and Cdk5 in scopolamine-induced Alzheimer's disease.
Aug 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Alzheimers Dis Rep. 2019 Aug 30 ;3(1):257-267. Epub 2019 Aug 30. PMID:
31754658
Article Published Date
: Aug 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin improves learning and memory ability in a mouse Alzheimer's disease experimental model.
May 05, 2008
Click here to read the entire abstract
Pubmed Data
: Chin Med J (Engl). 2008 May 5;121(9):832-9. PMID:
18701050
Article Published Date
: May 05, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Memory Disorders
,
Memory Loss
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin improves the tau-induced neuronal dysfunction that is independent of insoluble aggregates of tau.
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurobiol Aging. 2016 Mar ;39:69-81. Epub 2015 Dec 1. PMID:
26923403
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin inhibits amyloid-petpide induced changes associated with the progression of Alzheimer's disease.
Dec 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Neurochem. 2004 Dec;91(5):1199-210. PMID:
15569263
Article Published Date
: Dec 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Enzyme Inhibitors
,
Epidermal growth factor receptor (EGFR) inhibitor
,
Neuroprotective Agents
[+]
Curcumin may be a potential therapeutic agent that can regulate the critical molecules in brain insulin signalling pathways.
Jul 26, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Immunopathol Pharmacol. 2016 Jul 27. Epub 2016 Jul 27. PMID:
27466310
Article Published Date
: Jul 26, 2016
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin may have therapeutic value in Alzheimer disease prevention.
Nov 24, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2009 Nov 24. Epub 2009 Nov 24. PMID:
11755008
Article Published Date
: Nov 24, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Curcumin restores innate immune Alzheimer's disease risk gene expression to ameliorate Alzheimer pathogenesis.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2019 07 ;127:432-448. Epub 2019 Apr 2. PMID:
30951849
Article Published Date
: Dec 31, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Immunomodulatory
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Curcumin reverses amyloid pathology and associated neurotoxicity in a mouse model of Alzheimer disease.
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Neurochem. 2007 Aug;102(4):1095-104. Epub 2007 Apr 30. PMID:
17472706
Article Published Date
: Aug 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
Additional Keywords
:
Disease Reversal
[+]
Curcumin supplementation could ameliorate cognitive deficits and reverse biochemical alterations in a ICV-streptozotocin Alzheimer's rat model.
Jan 04, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Jan 5 ;770:52-60. Epub 2015 Dec 2. PMID:
26638997
Article Published Date
: Jan 04, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Curcumin treatment improves motor behavior in α-synuclein transgenic mice.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(6):e0128510. Epub 2015 Jun 2. PMID:
26035833
Article Published Date
: Dec 31, 2014
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Curcumin-loaded nanocapsules reverses the depressant-like behaviour and oxidative stress induced by β-amyloid.
Jan 14, 2019
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2019 12 15 ;423:122-130. Epub 2019 Nov 4. PMID:
31698022
Article Published Date
: Jan 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Curcuminoids (from Turmeric) enhance memory in mice through acetylcholinesterase inhibition.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Pharmacol Biochem Behav. 2009 Feb;91(4):554-9. Epub 2008 Oct 1. PMID:
18930076
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Memory Disorders
,
Memory Loss
Pharmacological Actions
:
Acetylcholinesterase Inhibitor
[+]
Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2010 Sep 1;169(3):1296-306. Epub 2010 Jun 9. PMID:
20538041
Article Published Date
: Sep 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Cyanidin-3-glucoside inhibits amyloid β25-35-induced neuronal cell death in cultured rat hippocampal neurons.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2018 Nov ;22(6):689-696. Epub 2018 Oct 25. PMID:
30402029
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cyanidin 3-glucoside
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Date seed extract may have advantageous effects in preventing Alzheimer's disease in male rats.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 May ;89:221-226. Epub 2017 Feb 20. PMID:
28231543
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Date Seeds
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Decrease in the generation of Amyloid-β due to Salvianolic acid B by modulating BACE1 activity.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Curr Alzheimer Res. 2017 ;14(11):1229-1237. PMID:
28413985
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Red Sage
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Diet supplementation with hydroxytyrosol ameliorates brain pathology and restores cognitive functions in a mouse model of amyloid-β deposition.
Apr 24, 2018
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 Apr 25. Epub 2018 Apr 25. PMID:
29710709
Article Published Date
: Apr 24, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Dietary lactoferrin supplementation prevents memory impairment and reduces amyloid-β generation.
Jan 23, 2020
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2020 Jan 24. Epub 2020 Jan 24. PMID:
31985470
Article Published Date
: Jan 23, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Alzheimer's Disease
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Dietary polyphenol plus exercise may exert beneficial effects on brain health and slow the progression of moderate- or mid-stages of AD.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacogn Mag. 2016 May ;12(Suppl 2):S139-46. Epub 2016 May 11. PMID:
27279698
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Epicatechin
Diseases
:
Alzheimer's Disease
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
[+]
Dietary supplementation of a high-temperature-processed green tea extract attenuates cognitive impairment.
Aug 28, 2019
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2019 Aug 29:1-8. Epub 2019 Aug 29. PMID:
31462168
Article Published Date
: Aug 28, 2019
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Green Tea
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Dietary supplementation of figs may be useful for the improvement of cognitive and behavioural deficits in Alzheimer's disease.
Jun 17, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2014 Jun 18. Epub 2014 Jun 18. PMID:
24938828
Article Published Date
: Jun 17, 2014
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Fig
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Dietary supplementation of walnuts improves memory deficits and learning skills in transgenic mouse model of Alzheimer's disease.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2014 ;42(4):1397-405. PMID:
25024344
Article Published Date
: Dec 31, 2013
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Walnut
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Dietary supplementation with apple juice decreases endogenous amyloid-beta levels in mouse brain.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2010 Oct;26(4):447-55. PMID:
19158432
Article Published Date
: Oct 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Apples
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.
Dec 30, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2010 Dec 30. Epub 2010 Dec 30. PMID:
19041676
Article Published Date
: Dec 30, 2010
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Resveratrol
,
Vitamin C
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Antioxidants
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Stilbenes
[+]
Diosgenin restores Aβ-induced axonal degeneration by reducing the expression of heat shock cognate 70.
Aug 02, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2018 Aug 3 ;8(1):11707. Epub 2018 Aug 3. PMID:
30076345
Article Published Date
: Aug 02, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Heat Shock Protein Down-Regulation
,
Neuroprotective Agents
[+]
Donepezil markedly potentiates memantine neurotoxicity.
Feb 01, 2008
Click here to read the entire abstract
Pubmed Data
: Neurobiol Aging. 2008 Feb ;29(2):153-67. Epub 2006 Nov 16. PMID:
17112636
Article Published Date
: Feb 01, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Drug Synergy
Problem Substances
:
Donepezil (trade name Aricept)
,
Memantine
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Effects of liquiritigenin treatment on the learning and memory deficits induced by amyloid beta-peptide (25-35) in rats.
Jun 25, 2010
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2010 Jun 26 ;210(1):24-31. Epub 2010 Feb 1. PMID:
20117143
Article Published Date
: Jun 25, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Memory Disorders
Pharmacological Actions
:
MicroRNA modulator
,
Neuroprotective Agents
[+]
EGCG can be used as an enhanced supplement for huperzine A to treat Alzheimer's disease.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2009 Aug;12(4):142-8. PMID:
19622237
Article Published Date
: Aug 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Huperzine
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Natural Substance Synergy
[+]
EGCG nanoparticles attenuate aluminum chloride induced neurobehavioral deficits.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2018 ;10:244. Epub 2018 Aug 13. PMID:
30150930
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
