Alzheimer's Disease

Name	AC	CK
Vitamin D	15	173
Curcumin	72	128
Huperzine	23	87
Ginkgo biloba	18	81
Vitamin E	12	72
Ginsenosides	42	66
Folic Acid	13	63
Melatonin	25	62
Resveratrol	34	44
Coconut Oil	11	41
Vitamin B-12	4	40
Flavonoids	22	39
Berberine	25	37
Alpha-Lipoic Acid	9	33
Probiotics	12	33
Saffron	13	33
Coffee	4	32
Sage	4	31
Vitamin B-6	3	30
Astaxanthin	18	26
Omega-3 Fatty Acids	6	26
Polyphenols	20	26
EGCG (Epigallocatechin gallate)	19	25
Caffeine	6	24
Cannabidiol	19	24
NAC (N-acetyl-L-cysteine)	4	24
B-complex	4	23
Lycopene	10	23
Polyunsaturated Fatty Acids (PUFAs)	5	23
Bacopa	15	22
Carotenoids	4	22
Lactoferrin	3	22
Lemon Balm	4	22
SAMe (S-adenosylmethionine)	3	22
Strawberry	4	22
DHA (Docosahexaenoic Acid)	9	21
Lutein	3	21
Carnitine, Acetyl-L-	2	20
Genistein	14	19
Green Tea	8	19
Rosmarinic acid	7	19
Tanshinone IIA	11	19
Lychee	9	18
Thymoquinone	10	18
Vitamin C	11	18
Fish Oil	5	17
Olive Oil	9	17
Selenium	5	17
Catechin	6	16
Nobiletin	9	16
Quercetin	12	16
Coconut	4	14
Cannabis	4	13
Gotu Kola	9	13
Medium Chain Triglycerides	2	13
Paeoniflorin	9	13
Rosemary	3	13
Sulforaphane	6	13
Apples	2	12
Crocin	8	12
Phosphatidylserine	2	12
Piperidines	2	12
Pomegranate	8	12
Puerarin	8	12
Royal Jelly	7	12
Apigenin	7	11
Ginger	8	11
Kefir	2	11
Lion's Mane (Hericium Erinaceus)	6	11
Luteolin	7	11
Oleocanthal	4	11
Spermidine	2	11
Turmeric	10	11
Anthocyanins	8	10
Baicalein	7	10
Coenzyme Q10	6	10
Fucoidan	6	10
GlyceroPhosphoCholine (alpha-GPC)	1	10
Magnesium	6	10
Melissa (Lemonbalm)	1	10
Monounsaturated fatty acids	1	10
Naringenin	8	10
Papaya: Fermented	1	10
Piperine	7	10
Reishi Mushroom	6	10
Sea Cucumber	1	10
Silica	1	10
Silica: Orthosilicic acid	1	10
Thiamine (B-1)	1	10
Tomato	1	10
Vitamin B-3 (Niacin)	1	10
Zeaxanthin	1	10
Ashwagandha	6	9
Cannabinoids	9	9
Cinnamon	7	9
Gastrodin	5	9
Lotus	6	9
Thymol	5	9
Walnut	6	9
Bee Venom	5	8
Goji	6	8
Honokiol	5	8
Mangosteen	6	8
Myricetin	6	8
Silibinin	4	8
Amla Fruit	5	7
Chokeberry	4	7
Ginseng (Korean)	5	7
Hesperidin	4	7
Persimmon	4	7
Safflower	4	7
Stilbenes	6	7
Blueberry	4	6
Citrus naringin	3	6
Emodin	3	6
Ferulic acid	4	6
Fisetin	4	6
Formononetin	4	6
Holy Basil	2	6
Licorice	4	6
Mangiferin	5	6
Oleuropein	5	6
Phloretin	3	6
Pterostilbene	4	6
Rose	3	6
Rosemaric Acid	4	6
S-Adenosylmethionine (SAMe)	4	6
Schisandra	3	6
Syrian rue	3	6
Theanine	3	6
Acetyl-l-carnitine	3	5
Asiatic Acid	4	5
Astragaloside	4	5
Bromelain	1	5
Brown Rice: Pre-Germinated	1	5
Cinnamaldehyde	3	5
Crocetin	3	5
Fenugreek	3	5
Fucoxanthin	4	5
Honeysuckle	4	5
Hydrogen Water	3	5
Hydroxytyrosol	3	5
Lactobacillus plantarum	3	5
Magnolol	3	5
Moringa oleifera	3	5
Mulberry	3	5
Nigella sativa (aka Black Seed)	5	5
Panax Notoginseng	3	5
Rutin	4	5
Ursolic Acid	3	5
Zataria multiflora	3	5
beta-Carotene	4	5
Angelica	2	4
Bamboo	3	4
Barberry	3	4
Basil	2	4
Betulinic acid	2	4
Bifidobacterium Lactis	2	4
Bitter Orange	2	4
Black Pepper	2	4
Caffeic Acid	2	4
Carnosic Acid	3	4
Citrus Peel	2	4
Diosgenin	2	4
Epicatechin	2	4
Eriodictyol	2	4
Frankincense	2	4
Gingerol	3	4
Ginseng	4	4
Grape	2	4
Grape Seed Extract	2	4
Hawthorn	3	4
Indian Mulberry	2	4
Kimchi	2	4
Lavender: Essential Oil	2	4
Oleanolic acid	3	4
Olive	3	4
Paeonol	3	4
Passion Flower	2	4
Radish	2	4
Seaweed: Brown	3	4
Vitexins	3	4
Zinc	3	4
6-Shogaol	3	3
Antrodia camphorata	2	3
Bael	2	3
Caprylic Acid	1	3
Carnosine	2	3
Carvacrol	2	3
Coptis chinensis	2	3
Cranberry	2	3
Cyanidin	3	3
Delta-tetrahydrocannabinol (THC)	3	3
Dogwood	3	3
EPA (Eicosapentaenoic Acid)	2	3
Eugenol	2	3
False Black Pepper	2	3
Hyperforin	2	3
Kudzu	2	3
Maple Syrup	2	3
Milk Thistle	2	3
Nicotinamide adenine dinucleotide (NADH)	2	3
Nordihydroguaiaretic acid (NDGA)	2	3
Oligosaccharides	2	3
Palmitoylethanolamide	2	3
Perilla	2	3
Piperlongumine	2	3
Plum	2	3
Policosanol	2	3
Prebiotics	3	3
Rhubarb	2	3
Rice Bran	2	3
Safranal	2	3
Salvia miltiorrhiza	3	3
Sesamin	2	3
Spirulina	2	3
Tannic Acid	2	3
Urolithin A	2	3
Wine	2	3
Wogonin	2	3
Zerumbone	2	3
Allicin	1	2
Anise	1	2
Ayurvedic Formulation: Chyawanprash	1	2
Babchi	1	2
Bay leaf	1	2
Beta Sitosterol	1	2
Bifidobacterium Bifidum	1	2
Bifidobacterium Breve	1	2
Bifidobacterium Longum	1	2
Bilberry	1	2
Biochanin A	2	2
Bisdemethoxycurcumin	2	2
Blackberry	2	2
Butterbur	1	2
Caffeic acid phenethyl ester	1	2
Capparis spinosa (caper)	1	2
Chaga Mushroom (Inonotus obliquus)	1	2
Chrysin	1	2
Cocoa	2	2
Coconut Water	1	2
Cordyceps Militaris	1	2
Curcuminoids	2	2
Curry Tree	1	2
Cyanidin 3-glucoside	1	2
Date Seeds	1	2
Eicosanoyl-5-hydroxytryptamide (EHT)	1	2
Estradiol (E(2))	1	2
Evening Primrose Oil	1	2
Evodia ruteacarpa	1	2
FOS (Fructooligosaccharides)	1	2
Fig	1	2
Folate	1	2
Fruit: All	2	2
Garlic: Aged	2	2
Gold (nanoparticles)	1	2
Grapefruit Seed Extract	1	2
Green Coffee Bean	1	2
Guarana	1	2
Hibiscus sabdariffa	1	2
Isoflavones	1	2
Jujube	1	2
Krill	1	2
Lactobacillus Acidophilus	1	2
Lactobacillus fermentum	1	2
Lactobacillus probiotics	1	2
Lauric acid	2	2
Lavender	1	2
Loquat	1	2
Lupeol	1	2
Mango	1	2
Mango leaf	1	2
Medicinal Mushrooms	2	2
Mint	1	2
Moxibustion	1	2
Myrtle	1	2
Nattokinase	1	2
Nettle	1	2
Niacin	1	2
Oregano	1	2
Oridonin	1	2
Orthosiphon	1	2
Pantethine	1	2
Peony	1	2
Pine Bark Extract	1	2
Pomegranate Peel	1	2
Prickly Pear Cactus	1	2
Propolis: Bee	1	2
Prunella vulgaris	1	2
Punicalagin	2	2
Pycnogenol (Pine Bark)	1	2
Raisins	1	2
Raspberry	2	2
Red Sage	1	2
Red Wine Extract	2	2
Red Yeast Rice	1	2
Rose Hips	1	2
Shikonin	1	2
Soy	1	2
St. Johns Wort	1	2
Star Fruit	1	2
Terminalia chebula	1	2
Ume (Japanese apricot)	1	2
Valerian	1	2
Vegetables: All	2	2
Vitamin B12: methylcobalamin	2	2
Xanthohumol	2	2
Xanthones	2	2
Yeast	1	2
Yerba Mate	1	2
acetyl-11-keto-beta-boswellic acid	1	2
Algae	1	1
Almond	1	1
Apple Cider Vinegar	1	1
Arginine	1	1
Asparagus	1	1
Avocado	1	1
Banana	1	1
Bee Propolis	1	1
Bergamot	1	1
Beta-glucan	1	1
Black Currant	1	1
Black Raspberry	1	1
Broccoli Sprouts	1	1
Cannabichromene	1	1
Cannabigerol	1	1
Cardamom	1	1
Carnosol	1	1
Carpolobia lutea	1	1
Chia	1	1
Chinese Skullcap	1	1
Chlorogenic Acid	1	1
Chromium	1	1
Colostrum	1	1
Copper	1	1
Coriandrum sativum	1	1
Corn Silk	1	1
Coumestrol	1	1
Culinary Herbs and Spices	1	1
Cysteine (see N-Acetylcysteine)	1	1
Daidzein	1	1
Demethoxycurcumin	1	1
Devils Claw	1	1
Echinacea	1	1
Ellagic Acid	1	1
Endocannabinoids	1	1
Essential Fatty Acids	1	1
Fermented Foods and Beverages	1	1
Gallic Acid	1	1
Garlic	1	1
Genipin	1	1
Guduchi	1	1
Gynostemma	1	1
Haritaki (Terminalia chebula)	1	1
Hazelnut	1	1
Honey	1	1
Hops	1	1
Icariin	1	1
Isoquercitrin	1	1
Japanese mugwort	1	1
Kaempferol	1	1
Kava Kava	1	1
L-Carnitine	1	1
Lignans	1	1
Liquiritigenin	1	1
Long Pepper	1	1
Lysergic Acid Diethylamide (LSD)	1	1
Lysine	1	1
Marijuana	1	1
Mistletoe	1	1
Mushrooms: All	1	1
Myrrh	1	1
Onion	1	1
P-Coumaric Acid	1	1
Panax Ginseng	1	1
Phytate	1	1
Piceatannol	1	1
Pistachio nut	1	1
Poria cocos	1	1
Proanthocyanidins	1	1
Propolis: Brazillian	1	1
Psychedelics:All	1	1
Red Marine Algae	1	1
Rice: Black	1	1
Ruta Graveolens	1	1
Sembung Leaf	1	1
Sesame Seeds	1	1
Silymarin	1	1
Soursop	1	1
Spikenard	1	1
Spinach	1	1
Tangeretin	1	1
Theophylline	1	1
Thistle	1	1
Thyme	1	1
Triptolide	1	1
Vitamin A	1	1
Vitamin B6	1	1
Vitamin E: alpha tocopherol	1	1
Water: Deep Sea	1	1
Water: Deuterium Depleted	1	1
White Mulberry	1	1
Yellow Sweet Clover (Melilotus officinalis)	1	1
neohesperidin	1	1
Muira Puama	1	0

Name	AC	CK
Donepezil (trade name Aricept)	6	73
Memantine	5	62
Aluminum	23	44
Aluminum Chloride	16	32
Cholinesterase Inhibitor Drugs	3	24
Antidepressants	1	20
Lead	4	14
Proton-Pump Inhibitors	2	11
Benzodiazepines	1	10
Hydrogenated Oil	1	10
Radon	1	10
Statin Drugs	1	10
Formaldehyde	3	6
Monosodium Glutamate (MSG)	3	6
Herbicides	1	5
Cadmium	2	3
Eptastigmine	1	3
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	2	3
Aluminum oxide	1	2
Antibiotics	1	2
Aspartame	1	2
Canola Oil	1	2
Glyphosate formulations	1	2
Heavy Metals	1	2
Paraquat	1	2
Roundup (herbicide)	1	2
Streptozotocin	1	2
Alcohol Consumption	1	1
Aluminium Cans	1	1
Bisphenol A	1	1
Galantamine	1	1
Pesticides	1	1
Polychlorinated biphenyls (PCBs)	1	1
Rivastigmine	1	1
Sugary soda	1	1
Tertiary butyl hydroperoxide	1	1

Name	AC	CK
Exercise	48	142
Exercise: Aerobic	5	41
Music	5	41
Dietary Modification: Mediterranean Diet	4	31
Acupuncture	4	23
Electroacupuncture	8	23
Meditation	4	22
Dietary Modification: Low Carbohydrate/Ketogenic	8	20
Light-Emitting Diodes (LEDs) Therapy	2	13
Integrative Medicine	2	11
Yoga	2	11
Exercise: Cycling	1	10
Massage/Therapeutic Touch	1	10
Mindfullness Training	1	10
Qigong	1	10
Sunlight exposure	1	10
Therapeutic Breathing	1	10
Laser Treatment: Low-Level	4	6
Fasting/Caloric Restriction	3	4
Hyperbaric Treatment	2	4
Exercise: Swimming	1	2
Aromatherapy	1	1
Art Therapy	1	1
Mind-Body Therapies	1	1

Name	AC	CK
Low Dose Ionizing Radiation	1	10
Shift Work	1	10
Electromagnetic Field Harms	3	4
Electromagnetic Radiation	2	3
Vaccination: All	3	3
Electromagnetic Radiation: 2.4 GHz	1	2
Mobile Phone Radiation	2	2
Microwave Radiation	1	1
Wi-Fi Radiation	1	1

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2015 ;14(1):76. Epub 2015 Aug 1. PMID: 26231781

Article Published Date : Dec 31, 2014

Study Type : Meta Analysis

Additional Links

Substances : Vitamin D

Diseases : Alzheimer's Disease, Dementia, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Cholinesterase inhibitor drug use is associated with increased incidence of bradycardia.Nov 01, 2009

Click here to read the entire abstract

Pubmed Data : J Am Geriatr Soc. 2009 Nov;57(11):1997-2003. Epub 2009 Sep 28. PMID: 19793162

Article Published Date : Nov 01, 2009

Study Type : Meta Analysis

Additional Links

Diseases : Alzheimer's Disease, Bradycardia, Dementia

Problem Substances : Cholinesterase Inhibitor Drugs, Donepezil (trade name Aricept)

[+]

Cognition enhancing effect of rosemary (Rosmarinus officinalis L.) in lab animal studies.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Braz J Med Biol Res. 2022 ;55:e11593. Epub 2022 Feb 9. PMID: 35170682

Article Published Date : Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Nutr. 2021 Sep 4 ;40(10):5327-5334. Epub 2021 Sep 4. PMID: 34537655

Article Published Date : Sep 03, 2021

Study Type : Meta Analysis

Additional Links

Substances : Vitamin C

Diseases : Alzheimer's Disease, Cardiovascular Diseases, Stroke, Vitamin C Deficiency

Pharmacological Actions : Cardioprotective

Additional Keywords : Risk Factors, Risk Reduction

[+]

These findings indicate a potential therapeutic role of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucosidein Alzheimer's disease therapy.Aug 25, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Neurol. 2019 Nov 13 ;19(1):284. Epub 2019 Nov 13. PMID: 31722673

Article Published Date : Nov 12, 2019

Study Type : Meta Analysis

Additional Links

Substances : Vitamin D

Diseases : Alzheimer's Disease, Dementia, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Vitamin D, cognition, and dementia: a systematic review and meta-analysis.Sep 24, 2012

Click here to read the entire abstract

Pubmed Data : Neurology. 2012 Sep 25 ;79(13):1397-405. PMID: 23008220

Article Published Date : Sep 24, 2012

Study Type : Meta Analysis

Additional Links

Substances : Vitamin D

Diseases : Alzheimer's Disease, Dementia, Dementia: Alzheimer Type, Vitamin D Deficiency

[+]

Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation.Mar 09, 2022

Pubmed Data : Clin Ther. 2003 Jan;25(1):178-93. PMID: 12637119

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : GlyceroPhosphoCholine (alpha-GPC)

Diseases : Alzheimer's Disease

[+]

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease.Oct 07, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Alzheimers Dement. 2018 Oct 8. Epub 2018 Oct 8. PMID: 30337151

Article Published Date : Oct 07, 2018

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease

Additional Keywords : Gut-brain Axis

[+]

Alzheimer's disease microbiome is associated with dysregulation of the anti-inflammatory P-glycoprotein pathway.May 06, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Pharm Ther. 2010 Apr;35(2):125-6. PMID: 20456731

Article Published Date : Apr 01, 2010

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Brain: Microglial Activation, Neurodegenerative Diseases

Adverse Pharmacological Actions : Neurotoxic

[+]

Circulating vitamin D levels and Alzheimer's disease.Dec 01, 2019

Click here to read the entire abstract

Pubmed Data : J Alzheimers Dis. 2019 Dec 2. Epub 2019 Dec 2. PMID: 31815694

Article Published Date : Dec 01, 2019

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Vitamin D Deficiency

Pharmacological Actions : Neuroprotective Agents

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : EBioMedicine. 2020 Jun 19:102834. Epub 2020 Jun 19. PMID: 32586758

Article Published Date : Jun 18, 2020

Study Type : Human Study

Additional Links

Substances : Lactoferrin

Diseases : Alzheimer's Disease

[+]

Dietary niacin may protect against Alzheimer's disease and age related cognitive decline.Jul 31, 2004

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Neurol Neurosurg Psychiatry. 2004 Aug ;75(8):1093-9. PMID: 15258207

Article Published Date : Jul 31, 2004

Study Type : Human Study

Additional Links

Substances : Vitamin B-3 (Niacin)

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

Different brain regions are infected with fungi in Alzheimer’s disease.Oct 14, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2015 Oct 15 ;5:15015. Epub 2015 Oct 15. PMID: 26468932

Article Published Date : Oct 14, 2015

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Fungus Diseases

[+]

Docosahexaenoic acid-rich fish oil supplementation reduces kinase associated with insulin resistance in overweight and obese midlife adults. May 29, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 May 30 ;12(6). Epub 2020 May 30. PMID: 32486256

Article Published Date : May 29, 2020

Study Type : Human Study

Additional Links

Substances : DHA (Docosahexaenoic Acid), Fish Oil

Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2, Insulin Resistance, Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Efficacy of Bacopa monnieri and donepezil in Alzheimer's disease and mild cognitive impairment.Oct 31, 2020

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Pubmed Data : Ann Indian Acad Neurol. 2020 Nov-Dec;23(6):767-773. Epub 2020 Dec 18. PMID: 33688125

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mediators Inflamm. 2015 ;2015:624801. Epub 2015 Apr 7. PMID: 25944987

Article Published Date : Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Aging Ment Health. 2009 Mar;13(2):183-90. PMID: 19347685

Article Published Date : Mar 01, 2009

Study Type : Human Study

Additional Links

Substances : Ginkgo biloba

Diseases : Alzheimer's Disease

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Ginkgo Biloba Leaf Extract Improves an Innate Immune Response of Peripheral blood leukocytes of Alzheimer's disease patients.May 10, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2022 May 11 ;14(10). Epub 2022 May 11. PMID: 35631163

Article Published Date : May 10, 2022

Study Type : Human Study

Additional Links

Substances : Ginkgo biloba

Diseases : Alzheimer's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Gram-negative bacterial molecules are associated with AD neuropathology.Nov 28, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Exp Gerontol. 2005 Apr;40(4):257-70. PMID: 15820606

Article Published Date : Apr 01, 2005

Study Type : Human Study

Additional Links

Substances : Monounsaturated fatty acids, Omega-3 Fatty Acids, Polyunsaturated Fatty Acids (PUFAs)

Diseases : Alzheimer's Disease, Cerebrovascular Disorders

Additional Keywords : Risk Reduction

[+]

Higher dietary intakes of flavonols may be associated with reduced risk of developing Alzheimer dementia.Jan 28, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neurology. 2020 Jan 29. Epub 2020 Jan 29. PMID: 31996451

Article Published Date : Jan 28, 2020

Click here to read the entire abstract

Pubmed Data : Neurology. 2018 May 15 ;90(20):e1789-e1798. Epub 2018 Apr 13. PMID: 29653991

Article Published Date : May 14, 2018

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease

Therapeutic Actions : Dietary Modification: Mediterranean Diet

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Alzheimer's disease, Dietary Modification: Mediterranean Diet, Neuroprotective Agents

[+]

Higher vitamin D dietary intake was associated with a lower risk of developing Alzheimer's disease among older women.Oct 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2012 Nov ;67(11):1205-11. Epub 2012 Apr 13. PMID: 22503994

Article Published Date : Oct 31, 2012

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

[+]

Click here to read the entire abstract

Pubmed Data : PLoS One. 2012 ;7(5):e35185. Epub 2012 May 2. PMID: 22567095

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Alzheimers Dement (N Y). 2022 ;8(1):e12278. Epub 2022 Mar 13. PMID: 35310529

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Glutathione, Olive

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Omega-3 FA intake combined with aerobic exercise and cognitive stimulation prevents atrophy in AD-related brain regions in MCI patients.Apr 30, 2016

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Pubmed Data : Neuroimage. 2016 May 1 ;131:226-38. Epub 2015 Oct 1. PMID: 26433119

Article Published Date : Apr 30, 2016

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Therapeutic Actions : Exercise: Aerobic, Integrative Medicine

Pharmacological Actions : Neuroprotective Agents

[+]

Oxidative stress and inflammation are associated with physical frailty in patients with Alzheimer's disease.Jun 13, 2016

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Pubmed Data : Geriatr Gerontol Int. 2016 Jun 14. Epub 2016 Jun 14. PMID: 27296166

Article Published Date : Jun 13, 2016

Study Type : Human Study

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Diseases : Alzheimer's Disease, Inflammation, Oxidative Stress

[+]

Participants randomized to the probiotic group will show greater improvements in psychological status compared to participants in the placebo group.Nov 30, 2018

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Pubmed Data : Contemp Clin Trials Commun. 2018 Dec ;12:192-197. Epub 2018 Nov 14. PMID: 30511028

Article Published Date : Nov 30, 2018

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease.Nov 19, 2019

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Pubmed Data : Sci Rep. 2017 07 17 ;7(1):5559. Epub 2017 Jul 17. PMID: 28717130

Article Published Date : Jan 16, 2017

Study Type : Human In Vitro, Human Study

Additional Links

Diseases : Alzheimer's Disease, Bacterial Infections, Fungus Diseases

[+]

Practice of simple mind-body therapies may alter plasma Aβ levels, telomere length, and telomerase activity.Dec 31, 2017

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Pubmed Data : J Alzheimers Dis. 2018 ;66(3):947-970. PMID: 30320574

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease

Therapeutic Actions : Meditation , Music

Additional Keywords : Risk Reduction

[+]

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Pubmed Data : J Neuroinflammation. 2017 01 3 ;14(1):1. Epub 2017 Jan 3. PMID: 28086917

Article Published Date : Jan 02, 2017

Study Type : Human Study

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Substances : Resveratrol

Diseases : Alzheimer's Disease, Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents

[+]

Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer's disease progression.Oct 28, 2020

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Pubmed Data : Dement Geriatr Cogn Disord. 2014 ;37(3-4):246-56. Epub 2013 Nov 15. PMID: 24247062

Article Published Date : Dec 31, 2013

Study Type : Human Study

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Substances : Carotenoids, Lutein, Lycopene, Tomato, Zeaxanthin

Diseases : Alzheimer's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Serum Vitamin D deficiency was associated with mild cognitive impairment and dementia.Dec 31, 2018

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Pubmed Data : Rev Invest Clin. 2019 ;71(6):381-386. PMID: 31823966

Article Published Date : Dec 31, 2018

Study Type : Human Study

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Substances : Vitamin D

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Dementia, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Silicic acid may reduce the body burden of aluminium in Alzheimer's patients.Dec 01, 2006

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Pubmed Data : Am J Obstet Gynecol. 2006 Dec;195(6):1693-9. Epub 2006 Jun 21. PMID: 16988476

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Pubmed Data : J Food Biochem. 2021 Feb 5:e13637. Epub 2021 Feb 5. PMID: 33547659

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Pubmed Data : Neurobiol Aging. 2008 Feb;29(2):203-9. Epub 2006 Nov 13. PMID: 17097768

Article Published Date : Feb 01, 2008

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Pineal Gland Calcification

Additional Keywords : Diseases that are Linked

[+]

The effect of electroacupuncture on improving mini-mental state examination in patients with Alzheimer's disease is similar to donepezil.Jan 11, 2019

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Pubmed Data : Zhongguo Zhen Jiu. 2019 Jan 12 ;39(1):3-8. PMID: 30672248

The spice sage and its active, neuroprotective ingredient rosmarinic acid could validate the traditional use of this spice in the treatment of Alzheimer's disease. Jun 01, 2006

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Pubmed Data : J Pharmacol Exp Ther. 2006 Jun;317(3):1143-9. Epub 2006 Feb 22. PMID: 16495207

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Pubmed Data : J Alzheimers Dis. 2017 Jun 22. Epub 2017 Jun 22. PMID: 28671130

Pubmed Data : Vet World. 2016 Dec ;9(12):1348-1354. Epub 2016 Dec 3. PMID: 28096604

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2015 ;2015:205247. Epub 2015 Jul 26. PMID: 26273596

Article Published Date : Dec 31, 2014

Study Type : Human In Vitro

Additional Links

Diseases : Alzheimer's Disease, Cancers: All, Inflammation

Additional Keywords : Diseases that are Linked

[+]

Thymoquinone holds a neuroprotective potential and could be a promising therapeutic agent to reduce the risk of developing Alzheimer's disease.Feb 28, 2019

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Pubmed Data : Biochem Biophys Rep. 2019 Mar ;17:122-126. Epub 2019 Jan 3. PMID: 30623116

Article Published Date : Feb 28, 2019

Study Type : Human In Vitro

Additional Links

Substances : Thymoquinone

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

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[+]

Investigating a curcumin-loaded PLGA-PEG-PLGA thermo-sensitive hydrogel for the prevention of Alzheimer's disease.Apr 06, 2022

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Pubmed Data : J Med Case Rep. 2014 Feb 10 ;8:41. Epub 2014 Feb 10. PMID: 24513181

Article Published Date : Feb 10, 2014

Study Type : Human: Case Report

Additional Links

Diseases : Alzheimer's Disease

Problem Substances : Aluminum

[+]

Transcranial LED therapy increased the cerebral blood flow in an elderly women.Dec 31, 2014

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Pubmed Data : Lasers Med Sci. 2015 Jan ;30(1):339-46. Epub 2014 Oct 3. PMID: 25277249

A combination of lycopene and vitamin E acted in a synergistic fashion to bring significant effects against oxidative stress in tauopathies.Dec 31, 2016

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Pubmed Data : J Alzheimers Dis. 2017 ;57(2):475-482. PMID: 28269786

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Pubmed Data : Food Sci Biotechnol. 2018 Aug ;27(4):1193-1200. Epub 2018 Apr 4. PMID: 30263850

Article Published Date : Jul 31, 2018

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean), Kudzu

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents

Additional Keywords : Natural Substance Synergy

[+]

A dihydroflavonoid naringin extends the lifespan of C. elegans and delays the progression of aging-related diseases.Dec 31, 2019

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Pubmed Data : Behav Brain Funct. 2015 ;11:13. Epub 2015 Mar 29. PMID: 25880991

Administration of pomegranate peel extract has neuroprotective effects involving multiple mechanisms.Dec 31, 2015

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Pubmed Data : PLoS One. 2016 ;11(11):e0166123. Epub 2016 Nov 9. PMID: 27829013

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Pubmed Data : Front Pharmacol. 2019 ;10:272. Epub 2019 Mar 26. PMID: 30971923

Article Published Date : Dec 31, 2018

Study Type : Animal Study

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Substances : Reishi Mushroom

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : DNA Methylation

[+]

Alleviation of fructose-induced Alzheimer's disease in rats by pioglitazone and decaffeinated green coffee bean extract.Apr 30, 2021

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Pubmed Data : J Food Biochem. 2021 May ;45(5):e13715. Epub 2021 Mar 29. PMID: 33782984

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Pubmed Data : Phytomedicine. 2008 Sep;15(9):710-21. Epub 2008 Apr 29. PMID: 18448320

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Angelica

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.Nov 27, 2017

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Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:5577163. Epub 2021 Aug 10. PMID: 34422074

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Pubmed Data : Neurobiol Learn Mem. 2021 Aug 31:107506. Epub 2021 Aug 31. PMID: 34478861

Article Published Date : Aug 30, 2021

Study Type : Animal Study

Additional Links

Substances : Mugwort

Diseases : Alzheimer's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Ascorbic acid ameliorates behavioural deficits and neuropathological alterations in rat model of Alzheimer's disease.Feb 05, 2017

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Pubmed Data : Environ Toxicol Pharmacol. 2017 Feb 6 ;50:200-211. Epub 2017 Feb 6. PMID: 28192749

Pubmed Data : Neurotox Res. 2019 Jan 22. Epub 2019 Jan 22. PMID: 30671870

[+]

B. breve A1 has therapeutic potential for preventing cognitive impairment in Alzheimer's disease.Oct 17, 2017

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Pubmed Data : Sci Rep. 2017 Oct 18 ;7(1):13510. Epub 2017 Oct 18. PMID: 29044140

Article Published Date : Oct 17, 2017

Study Type : Animal Study

Additional Links

Substances : Bifidobacterium Breve

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Bacopa enhances cognitive function and protects against neurodegeneration in an Alzheimer's disease model. Oct 04, 2009

Pubmed Data : PLoS One. 2015 ;10(7):e0131862. Epub 2015 Jul 10. PMID: 26161865

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Pubmed Data : Neuropsychiatr Dis Treat. 2016 ;12:3145-3152. Epub 2016 Dec 9. PMID: 28003750

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Baicalein

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Alzheimer's disease, Baicalein, Dose Response, Neuroprotective Agents

[+]

Bamboo extract inhibits neuronal secretion of Alzheimer's beta-amyloid peptides.Dec 01, 2003

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Pubmed Data : Neurochem Res. 2003 Dec;28(12):1785-92. PMID: 14649718

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Pubmed Data : ACS Chem Neurosci. 2021 May 13. Epub 2021 May 13. PMID: 33983710

Article Published Date : May 12, 2021

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Berberine improves cognitive impairment by simultaneously impacting cerebral blood flow and β-amyloid accumulation.May 10, 2021

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Pubmed Data : Transl Psychiatry. 2021 10 20 ;11(1):542. Epub 2021 Oct 20. PMID: 34671017

Article Published Date : Jan 19, 2021

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba

Diseases : Alzheimer's Disease

Pharmacological Actions : Neuroprotective Agents

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View the Evidence: 1625 Abstracts with Alzheimer's Disease Research

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21 percent of patients who receive donepezil discontinue treatment due to adverse side effects.Dec 07, 2009

Alzheimer disease is associated with a low concentration of serum vitamin E in older people.Aug 22, 2017

Alzheimer's disease cases have lower serum vitamin D concentrations than matched controls. Oct 04, 2012

An increased peripheral level of inflammatory markers is associated with a modest increase in risk of all-cause dementia.Mar 31, 2013

Antidepressant drug usage is associated with higher odds of Alzheimer’s disease and dementia.Dec 27, 2016

Available data indicates that lower vitamin D status may be associated with increased risk of developing AD and dementia.Dec 31, 2014

Cholinesterase inhibitor drug use is associated with increased incidence of bradycardia.Nov 01, 2009

Cognition enhancing effect of rosemary (Rosmarinus officinalis L.) in lab animal studies.Dec 31, 2021

Donepezil and memantine are known to cause bradycardia and to reduce the epileptogenic threshold.May 01, 2010

Ginkgo biloba is potentially beneficial for the improvement of cognitive function in patients with mild cognitive impairment or Alzheimer's disease.Dec 31, 2015

Higher coffee consumption is associated with reduced risk for Alzheimer disease.May 31, 2016

Higher levels of serum 25(OH)D was associated with a lower risk of dementia and Alzheimer's disease.Feb 14, 2018

Huperzine A appears to have beneficial effects on improvement of cognitive function.Dec 31, 2012

Huperzine A is a well-tolerated drug that could significantly improve cognitive performance in patients with Alzheimer's disease and vascular dementia.Dec 31, 2013

Memantine does not appear to have proven benefit for mild to moderate alzheimer disease.Jan 01, 2005

Meta-analytic findings suggested overall benefits of EGb 761 for stabilizing or slowing decline in cognition of subjects with cognitive impairment and dementia.Dec 31, 2014

Results of this meta-analytic study suggested that T. gondii can be considered a risk factor for the development of Alzheimer's disease.Sep 15, 2019

The impact of plasma vitamin C levels on the risk of cardiovascular diseases and Alzheimer's disease.Sep 03, 2021

These findings indicate a potential therapeutic role of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucosidein Alzheimer's disease therapy.Aug 25, 2016

This meta-analysis provided some evidence that melatonin improves sleep quality in patients with AD and PD.Aug 08, 2015

This study shows a strongly positive association between bacterial infection and Alzheimer's disease.Dec 31, 2014

Vitamin D deficiency as a risk factor for dementia and Alzheimer's disease: an updated meta-analysis.Nov 12, 2019

Vitamin D, cognition, and dementia: a systematic review and meta-analysis.Sep 24, 2012

Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation.Mar 09, 2022

A ketogenic supplement improves white matter energy supply and processing speed in mild cognitive impairment.Dec 31, 2020

A multi-vitamin/nutrient formula has therapeutic value in early-stage Alzheimer's diease. Dec 01, 2008

A multi-vitamin/nutrient formula has therapeutic value in moderate-stage to later-stage Alzheimer's diease. Feb 01, 2009

A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae.Feb 28, 2019

A supplement containing huperzine A and curcumin in dementia patients and individuals with mild cognitive impairment had beneficial effects.Dec 31, 2017

Acupuncture improves the overall function, cognition and activity of daily life in patients and the efficacy was superior to donepezil.Nov 30, 2014

Acupuncture is a safe and is effective in improving the cognitive function and global clinical status of Alzheimer's disease.Dec 28, 2017

Adding medical cannabis oil to AD patients' pharmacotherapy is safe and a promising treatment option.Jan 11, 2016

Administration of saffron capsules was comparable with memantine in reducing cognitive decline in patients with moderate to severe AD.Jun 30, 2014

Aerobic exercise in early Alzheimer’s disease is associated with benefits in functional ability.Dec 31, 2016

Aerobic exercise sustains performance of instrumental activities of daily living in early-stage Alzheimer disease.Dec 27, 2017

Aerobic fitness may have a positive influence on protection of brain even in aMCI CSF biomarker, a high-risk population to convert to AD.May 31, 2016

Air pollution is associated with cognitive deterioration of Alzheimer's disease.Apr 20, 2021

Alpha lipoic acid is an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Oct 01, 2008

Alpha lipoic appears to be an effective neuroprotective agent in Alzheimer's disease. Jan 01, 2007

Alpha-GPC improves cognitive function in mild to moderate Alzhemier's dementia.Jan 01, 2003

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease.Oct 07, 2018

Alzheimer's disease microbiome is associated with dysregulation of the anti-inflammatory P-glycoprotein pathway.May 06, 2019

Antioxidant beverages could be used as a natural complementary therapy to alleviate or decrease oxidative stress in Alzheimer’s disease.Aug 22, 2015

B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.Jul 21, 2011

Benzodiazepine and related drug use in general was associated with modestly increased risk of Alzheimer's disease.May 30, 2018

Breath Qigong improves recognition in seniors With vascular cognitive impairment.Dec 31, 2018

Caffeine given at breakfast significantly stimulated ketone production in a dose-dependent manner.Nov 24, 2016

Caffeine in coffee can prevent and help brain function in Alzheimer's DiseaseSep 01, 2009

Chronic consumption of proton pump inhibitors may increase the risk for Alzheimer disease.Apr 01, 2010

Circulating vitamin D levels and Alzheimer's disease.Dec 01, 2019

Cocoa procyanidins attenuate lipid peroxidation associated neuronal cell death in a manner relevant to Alzheimer's disease.May 15, 2009

Coconut oil was found to be beneficial in female patients with Alzheimer's dementia.Dec 31, 2014

Consumption of strawberries and foods rich in vitamin C, pelargonidin, anthocyanidins, and total flavonoids may reduce the risk of Alzheimer's dementia.Dec 13, 2019

Curcumin appears to enhance clearance of amyloid-beta in Alzheimer's disease patients.Sep 01, 2006

Decreased brain volume in adults with childhood lead exposure.May 26, 2008

Decreased salivary lactoferrin levels are specific to Alzheimer's disease Jun 18, 2020

Dietary niacin may protect against Alzheimer's disease and age related cognitive decline.Jul 31, 2004

Different brain regions are infected with fungi in Alzheimer’s disease.Oct 14, 2015

Docosahexaenoic acid-rich fish oil supplementation reduces kinase associated with insulin resistance in overweight and obese midlife adults. May 29, 2020

Efficacy of Bacopa monnieri and donepezil in Alzheimer's disease and mild cognitive impairment.Oct 31, 2020

Exercise capacity is strongly associated with cognitive function.Jan 31, 2017

Exercise reduced neuropsychiatric symptoms in patients with mild Alzheimer's disease.Dec 09, 2015

Fermented papaya has antioxidant actions in AD patients and that it may be a prophylactic food against neurological diseases associated with free radical overproduction.Dec 31, 2014

Folic acid deficiency may play a key role in neurodegenerative disorders. Jun 15, 2007

Gingko biloba compares favorably to the drug Aricept (donepezil) for the treatment of Alzheimer's dementia.Sep 01, 2006

Ginkgo biloba is as effective as the drug donepezil (Aricept) in improving symptoms of Alzheimers, but with less side effects. Mar 01, 2009

Ginkgo Biloba Leaf Extract Improves an Innate Immune Response of Peripheral blood leukocytes of Alzheimer's disease patients.May 10, 2022

Gram-negative bacterial molecules are associated with AD neuropathology.Nov 28, 2016

Herpes simplex virus type 1 in brain and risk of Alzheimer's disease.Jan 24, 1997

High homocysteine levels may be associated with the pathogenesis of neurological disorders.Jan 01, 2010

High intake of polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) reduce the risk of cognitive decline and dementia associated with Alzheimer's disease and/or vascular dsyfunction. Apr 01, 2005

Alzheimer's Disease

View the Evidence:
1625 Abstracts with Alzheimer's Disease Research