Arterial Calcification

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19 Substances Researched for Arterial Calcification
NameACCKFocus
Garlic532Locked
Vitamin K616Locked
Vitamin K2414Locked
Magnesium312Locked
Arginine110Locked
B-complex110Locked
Fiber110Locked
Garlic: Aged110Locked
Menaquinone 110Locked
Omega-3 Fatty Acids110Locked
Vitamin B-12110Locked
Vitamin D110Locked
Citric Acid 15Locked
Phytate34Locked
Cysteine (see N-Acetylcysteine)12Locked
Hawthorn11Locked
Nobiletin 11Locked
Onion11Locked
Piperlongumine 11Locked
6 Problem Substances Researched for Arterial Calcification
NameACCKFocus
Calcium Carbonate432Locked
Statin Drugs330Locked
Sodium Fluoride211Locked
Sugar Sweetened Beverages110Locked
Warfarin110Locked
Fluoride23Locked
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View the Evidence:
45 Abstracts with Arterial Calcification Research

[+]

Vascular and valvular calcification are potential side effects of Vitamin K antagonists.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cardiovasc Med. 2022 ;9:938567. Epub 2022 Aug 19. PMID: 36061545
Article Published Date : Dec 31, 2021
Study Type : Meta Analysis, Review
Additional Links
Diseases : Arterial Calcification, Vascular Calcification
Additional Keywords : Increased Risk
Problem Substances : Anticoagulants
[+]

Aged Garlic Extract (AGE) inhibits the rate of progression of coronary calcification in patients receiving statin therapy. Nov 01, 2004

Pubmed Data : Prev Med. 2004 Nov;39(5):985-91. PMID: 15475033
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Substances : Garlic
Diseases : Arterial Calcification, Arterial Plaque
[+]

Aged garlic extract reduces low attenuation plaque in coronary arteries of patients with diabetes.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1457-1461. Epub 2019 Dec 27. PMID: 32010322
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Arterial Calcification, Atherosclerosis, Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-atherogenic
[+]

Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis.Feb 01, 2004

Pubmed Data : Breast Cancer Res Treat. 2004 Feb;83(3):221-31. PMID: 19573556
Article Published Date : Feb 01, 2004
Study Type : Human Study
Additional Links
Substances : Arginine, B-complex, Garlic, Vitamin B-12
Diseases : Arterial Calcification, Atherosclerosis, Hypertension
Pharmacological Actions : Cardioprotective
Additional Keywords : Plant Extracts
[+]

Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.Feb 28, 2013

Pubmed Data : Int J Cardiol. 2013 Mar 1. Epub 2013 Mar 1. PMID: 23453866
Article Published Date : Feb 28, 2013
Study Type : Human Study
Additional Links
Substances : Garlic
Diseases : Arterial Calcification, Coronary Artery Disease, High Homocysteine
Pharmacological Actions : Cardioprotective
[+]

Arterial stiffness and vascular calcification in end-stage renal disease is adversely effected by the dose of calcium carbonate ingested. Jul 01, 2000

Pubmed Data : Nephrol Dial Transplant. 2000 Jul;15(7):1014-21. PMID: 10862640
Article Published Date : Jul 01, 2000
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification, Kidney Failure
Problem Substances : Calcium Carbonate
[+]

Calcified atherosclerosis is directly implicated in the pathogenesis of both abdominal aorta and iliac arteries.Jul 01, 2008

Pubmed Data : J Vasc Surg. 2008 Jul;48(1):121-7. Epub 2008 Jun 2. PMID: 18515037
Article Published Date : Jul 01, 2008
Study Type : Human Study
Additional Links
Diseases : Aortic Aneurysm, Arterial Calcification, Arteriosclerosis, Cardiovascular Diseases
Additional Keywords : Diseases that are Linked
[+]

Calcium carbonate supplements are associated with aortic calcification in hemodialysis patients. Jan 01, 2008

Pubmed Data : Ren Fail. 2008;30(10):952-8. PMID: 19016145
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification
Problem Substances : Calcium Carbonate
[+]

High dietary menaquinone (Vitamin K2) intake is associated with reduced coronary calcification.Apr 01, 2009

Pubmed Data : Atherosclerosis. 2009 Apr;203(2):489-93. Epub 2008 Jul 19. PMID: 18722618
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Substances : Menaquinone , Vitamin K2
Diseases : Arterial Calcification, Cardiovascular Diseases, Coronary Artery Disease
Pharmacological Actions : Cardioprotective
[+]

High levels of sugar-sweetened beverage consumption are associated with a higher prevalence and degree of coronary artery calcium.Jun 30, 2016

Pubmed Data : Am Heart J. 2016 Jul ;177:17-24. Epub 2016 Apr 16. PMID: 27297845
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification, Calcification: Arterial
Additional Keywords : Increased Risk
Problem Substances : Sugar Sweetened Beverages
[+]

Magnesium may have a favorable effect on coronary artery calcification. Oct 01, 2009

Pubmed Data : Hemodial Int. 2009 Oct;13(4):453-9. Epub 2009 May 12. PMID: 19469885
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Arterial Calcification, Coronary Artery Disease
[+]

More frequent statin use is associated with accelerated coronary artery calcification, and in a subpopulation aortic calcification, in T2DM patients with advanced atherosclerosis.Aug 07, 2012

Pubmed Data : Diabetes Care. 2012 Aug 8. Epub 2012 Aug 8. PMID: 22875226
Article Published Date : Aug 07, 2012
Study Type : Human Study
Additional Links
Diseases : Aortic Calcification, Arterial Calcification, Coronary Artery Disease, Diabetes: Cardiovascular Illness
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic
[+]

Omega-3 fatty acids and vitamin D supplementation results in a substantial reduction in coronary calcium scores and slowed plaque growth. Jul 01, 2009

Pubmed Data : Am J Ther. 2009 Jul-Aug;16(4):326-32. PMID: 19092644
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids, Vitamin D
Diseases : Arterial Calcification, Arterial Plaque, Arterial Thickening, Coronary Artery Disease
Additional Keywords : Disease Regression
[+]

Patients with higher tooth loss have a greater prevalence of carotid artery calcification.Aug 26, 2016

Pubmed Data : Oral Dis. 2016 Aug 27. Epub 2016 Aug 27. PMID: 27566532
Article Published Date : Aug 26, 2016
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification
Additional Keywords : Risk Factors
[+]

Statin therapy was associated with greater progression of coronary artery calcification.Dec 29, 2016

Pubmed Data : Eur J Clin Invest. 2016 Dec 30. Epub 2016 Dec 30. PMID: 28036114
Article Published Date : Dec 29, 2016
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification, Drug-Induced Nutrient Depletion: Statin Drugs, Vitamin K Deficiency
Additional Keywords : Risk Factors
Problem Substances : Statin Drugs
[+]

Statin use is associated with an increased prevalence and extent of coronary plaques possessing calcium.Aug 23, 2012

Pubmed Data : Atherosclerosis. 2012 Aug 24. Epub 2012 Aug 24. PMID: 22981406
Article Published Date : Aug 23, 2012
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification, Coronary Artery Disease, Ectopic Calcification, Statin-Induced Pathologies
Problem Substances : Statin Drugs
[+]

The progression of coronary artery calcification in predialysis patients is paralleled by the amount of calcium carbonate they consume. Nov 01, 2007

Pubmed Data : Kidney Int. 2007 Nov;72(10):1255-61. Epub 2007 Sep 5. PMID: 17805238
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification, Coronary Artery Disease
Problem Substances : Calcium Carbonate
[+]

There is an association of vascular fluoride uptake with vascular calcification and coronary artery disease.Jan 01, 2012

Pubmed Data : Nucl Med Commun. 2012 Jan ;33(1):14-20. PMID: 21946616
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification, Ectopic Calcification, Vascular Calcification
Problem Substances : Sodium Fluoride
[+]

Total dietary fiber reveals modest inverse associations with poor glycemic control.Apr 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2019 Apr 3 ;18(1):23. Epub 2019 Apr 3. PMID: 30943964
Article Published Date : Apr 02, 2019
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Arterial Calcification, Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents
[+]

Vitamin D deficiency had a significant positive association with the presence of coronary artery calcification.Jun 16, 2016

Pubmed Data : J Am Coll Nutr. 2016 Jun 17:1-7. Epub 2016 Jun 17. PMID: 27315115
Article Published Date : Jun 16, 2016
Study Type : Human Study
Additional Links
Diseases : Arterial Calcification, Atherosclerosis, Vitamin D Deficiency
Additional Keywords : Increased Risk
[+]

Vitamin K supplementation inhibits the progression of coronary artery calcification in oldern men and women. Jun 01, 2009

Pubmed Data : Am J Clin Nutr. 2009 Jun;89(6):1799-807. Epub 2009 Apr 22. PMID: 19386744
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K
Diseases : Arterial Calcification, Coronary Artery Disease, Ectopic Calcification
[+]

Warfarin use increases the risk of valvular calcification.Dec 01, 2009

Pubmed Data : J Thromb Haemost. 2009 Dec;7(12):2023-7. Epub 2009 Sep 28. PMID: 19793187
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Diseases : Aortic Calcification, Arterial Calcification
Problem Substances : Warfarin
[+]

Citric acid as a decalcifying agent for the excised calcified human heart valves.Mar 31, 2008

Pubmed Data : Anadolu Kardiyol Derg. 2008 Apr ;8(2):94-8. PMID: 18400627
Article Published Date : Mar 31, 2008
Study Type : Human In Vitro
Additional Links
Substances : Citric Acid
Diseases : Arterial Calcification
Pharmacological Actions : Cardioprotective
[+]

Andrographolide ameliorates aortic valve calcification.Jan 11, 2021

Pubmed Data : Cell Calcium. 2021 12 ;100:102495. Epub 2021 Oct 21. PMID: 34740021
Article Published Date : Jan 11, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Arterial Calcification
Pharmacological Actions : Cardioprotective, Vasoprotective
[+]

Calcium carbonate deposits have been found in the walls of major arteries in atherosclerosis. Jan 01, 1983

Pubmed Data : Arkh Patol. 1983;45(8):76-81. PMID: 6639399
Article Published Date : Jan 01, 1983
Study Type : Animal Study
Additional Links
Diseases : Arterial Calcification, Arteriosclerosis
Problem Substances : Calcium Carbonate
[+]

Capsaicin attenuates arterial calcification.Dec 31, 2021

Pubmed Data : Hypertension. 2022 05 ;79(5):906-917. Epub 2022 Mar 2. PMID: 35232219
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Capsaicin
Diseases : Arterial Calcification, Atherosclerosis
[+]

Effect of water fluoridation on the development of medial vascular calcification in uremic rats.Apr 05, 2014

Pubmed Data : Toxicology. 2014 Apr 6 ;318:40-50. Epub 2014 Feb 18. PMID: 24561004
Article Published Date : Apr 05, 2014
Study Type : Animal Study
Additional Links
Diseases : Arterial Calcification, Atheroma, Atherosclerosis, Chronic Kidney Disease (CKD), Ectopic Calcification, Fluoride Toxicity
Problem Substances : Fluoride
Adverse Pharmacological Actions : Cardiotoxic
[+]

Emodin alleviates aortic valvular calcification by inhibiting the AKT/FOXO1 pathway.Dec 23, 2021

Pubmed Data : Ann Anat. 2021 Dec 24:151885. Epub 2021 Dec 24. PMID: 34958913
Article Published Date : Dec 23, 2021
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Arterial Calcification
Pharmacological Actions : Vasoprotective
[+]

Evidence shows that deficiency of Vit. K may contribute to the development of cardiovascular plaque (increased intima media thickness) and supplementation may reverse or forestall the process of calcification. Apr 01, 2007

Pubmed Data : Blood. 2007 Apr 1;109(7):2823-31. PMID: 17138823
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Substances : Vitamin K
Diseases : Arterial Calcification, Arterial Plaque
[+]

N-acetyl cysteine inhibits arthersclerosis in uremic rabbits. Jan 01, 2008

Pubmed Data : Am J Respir Crit Care Med. 2008 Jan 1;177(1):56-65. Epub 2007 Oct 4. PMID: 18356775
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine)
Diseases : Arterial Calcification, Arterial Plaque, Arteriosclerosis, Uremia
[+]

Phytate inhibits vascular caclification. Jul 01, 2007

Pubmed Data : Circ J. 2007 Jul;71(7):1152-6. PMID: 17587727
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Phytate
Diseases : Aortic Calcification, Arterial Calcification, Ectopic Calcification
[+]

Phytate prevents tissue calcifications in female rats.Dec 31, 1999

Pubmed Data : Biofactors. 2000 ;11(3):171-7. PMID: 10875304
Article Published Date : Dec 31, 1999
Study Type : Animal Study
Additional Links
Substances : Phytate
Diseases : Arterial Calcification
[+]

Vitamin K2 can inhibit calcification of aortic intima in mice.Dec 31, 2016

Pubmed Data : Vascular. 2017 Jan 1:1708538117713395. Epub 2017 Jan 1. PMID: 28587577
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin K2
Diseases : Arterial Calcification, Atherosclerosis
Pharmacological Actions : Anti-atherogenic
[+]

Fluorine is a factor in premature aging, and related adverse health effects. Jan 01, 2004

Pubmed Data : Ann Acad Med Stetin. 2004 ;50 Suppl 1:9-13. PMID: 16892576
Article Published Date : Jan 01, 2004
Study Type : Review
Additional Links
Diseases : Aging, Arterial Calcification
Problem Substances : Fluoride, Sodium Fluoride
Adverse Pharmacological Actions : Cardiotoxic
[+]

Garlic inhibits arteriosclerotic plaque formation, in vitro. Nov 01, 2004

Pubmed Data : Wien Med Wochenschr. 2004 Nov;154(21-22):515-22. PMID: 15638070
Article Published Date : Nov 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Garlic
Diseases : Arterial Calcification, Arterial Plaque, Arterial Thickening
[+]

Hawthorn, onion and garlic may dissolve hydroxapatite crystals associated with arteriosclerosis. Jan 01, 2003

Pubmed Data : Folia Med Cracov. 2003;44(1-2):187-99. PMID: 15232901
Article Published Date : Jan 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Garlic, Hawthorn, Onion
Diseases : Arterial Calcification, Arteriosclerosis
Additional Keywords : Decalcification
[+]

Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Feb 1 ;8(1):2069. Epub 2018 Feb 1. PMID: 29391410
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Magnesium
Diseases : Arterial Calcification, Chronic Kidney Disease (CKD)
[+]

Magnesium reduces calcification in bovine vascular smooth muscle cells in a dose-dependent manner.Jul 12, 2011

Pubmed Data : Nephrol Dial Transplant. 2011 Jul 12. Epub 2011 Jul 12. PMID: 21750166
Article Published Date : Jul 12, 2011
Study Type : In Vitro Study
Additional Links
Substances : Magnesium
Diseases : Arterial Calcification, Ectopic Calcification, Vascular Calcification
[+]

Nobiletin is a natural product to prevent the occurrence of heart valve calcification.May 31, 2019

Pubmed Data : Phytother Res. 2019 Jun ;33(6):1717-1725. Epub 2019 Apr 23. PMID: 31016813
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Nobiletin
Diseases : Arterial Calcification, Heart Disease
Pharmacological Actions : Cardioprotective
[+]

Piperlongumine attenuates high calcium/phosphate-induced arterial calcification.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cardiovasc Med. 2020 ;7:625215. Epub 2021 Feb 10. PMID: 33644124
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Arterial Calcification, Atherosclerosis
Pharmacological Actions : Vasoprotective
[+]

Vitamin K may be effective in preventing and treating osteoporosis and arterial calcification.Aug 01, 2005

Pubmed Data : Am J Health Syst Pharm. 2005 Aug 1;62(15):1574-81. PMID: 16030366
Article Published Date : Aug 01, 2005
Study Type : Review
Additional Links
Substances : Vitamin K
Diseases : Arterial Calcification, Osteopenia, Osteoporosis
Additional Keywords : Calcification Paradox
[+]

Vitamin K may reduce the risk for artherosclerosis. Sep 01, 2000

Pubmed Data : Diabetes Care. 2000 Sep;23(9):1227-31. PMID: 18196985
Article Published Date : Sep 01, 2000
Study Type : Review
Additional Links
Substances : Vitamin K
Diseases : Arterial Calcification, Arteriosclerosis
[+]

Vitamin K supplementation may be useful for a number of chronic conditions.Dec 31, 2016

Pubmed Data : J Nutr Metab. 2017 ;2017:6254836. Epub 2017 Jun 18. PMID: 28698808
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Arterial Calcification, Arthritis, Cancers: All, Diabetes Mellitus: Type 2, Osteoporosis
[+]

Vitamin K2 can be an interesting strategy in benefitting bone and vascular health.Dec 11, 2017

Pubmed Data : Crit Rev Food Sci Nutr. 2017 Dec 12 ;57(18):3959-3970. PMID: 27437760
Article Published Date : Dec 11, 2017
Study Type : Review
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Arterial Calcification, Osteoporosis
[+]

Inositol hexaphosphate (phytate) inhibits calcification of the cardiovascular system.Jan 01, 2006

Pubmed Data : Front Biosci. 2006 Jan 1;11:136-42 PMID: 16146720
Article Published Date : Jan 01, 2006
Additional Links
Substances : Phytate
Diseases : Arterial Calcification

Copyright: Eraxion / 123RF Stock Photo

Arterial Calcification Related Articles

Garlic Prevents Artery Calcification and Infection
Written by Dr. Jeffrey Dach, MD
Aged garlic shows promising effects on reducing elevated coronary calcium scores while also acting as a gut-friendly antimicorbial
Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency
Written by Suzanne Humphries, MD
It saddens me to see older women diagnosed with "osteopenia" or "osteoporosis" listening to their doctors and taking supplemental calcium and even problematic drugs called bisphosphonates. These are irrational, dogmatic, harmful approaches to the problem of degrading bone as we age
Omega-3 and Vascular Disease
Written by Pat Robinson
Omega-3 fatty acids have a wide range of researched therapeutic properties, many of which are applicable to vascular disease. Omega-3 research is cited in its connection to cardiac mortality risk, peripheral artery disease and hypertension.
Taking Calcium Supplements Causes Brain Lesions
Written by Sayer Ji, Founder
Taking calcium supplements -- even at low doses -- linked to brain lesions in the first study of its kind.
Garlic: Roto-Rooter for the Arteries?
Written by Sayer Ji, Founder
One of the most common kitchen staples could prove to also be one of the most effective natural treatments for heart disease

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