Aspirin-Induced Toxicity

Name	AC	CK
Enterococcus faecium	1	10
Lactobacillus gasseri	1	10
Lactobacillus rhamnosus	1	10
Vitamin C	1	10
Yoghurt	1	10
Banana	4	8
Vitamin E	4	8
Fucoidan	3	5
Lemon	3	5
Cardamom	2	4
Flavonoids	2	4
Hydrogen Water	2	4
Mululuza	2	4
Nigella sativa (aka Black Seed)	2	4
Palm Tree	2	4
Spirulina	2	4
Sulforaphane	2	4
Goji	2	3
Aloe Vera	1	2
Apple Polyphenols	1	2
Apples	1	2
Artesunate	1	2
Astaxanthin	1	2
Astragaloside	1	2
Bael	1	2
Basil	1	2
Fructose	1	2
Geranium	1	2
Ginkgo biloba	1	2
Glucose	1	2
Hesperidin	1	2
Honey	1	2
Lactobacillus casei	1	2
Maltose	1	2
Mussel: Green-lipped (Perna canaliculus)	1	2
Panax Notoginseng	1	2
Phosphatidylcholine	1	2
Pomegranate	1	2
Satsuma	1	2
Sembung Leaf	1	2
Sucrose	1	2
Tocotrienols	1	2
Turmeric	1	2
Zucchini	1	2

Name	AC	CK
Aspirin	36	126
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	3	5
Ibuprofen	1	2
Indomethacin	1	2
Plutonium 238	1	2
Allopurinol	1	1
Antibiotics	1	1

Name	AC	CK	Focus
Photobiomodulation	1	2

[+]

This analysis suggests Helicobacter pylori increases the risk of low-dose aspirin ulcers.Nov 07, 2018

Click here to read the entire abstract

Pubmed Data : J Gastroenterol Hepatol. 2018 Nov 8. Epub 2018 Nov 8. PMID: 30408229

Article Published Date : Nov 07, 2018

Study Type : Meta Analysis

Additional Links

Diseases : Aspirin-Induced Toxicity , Gastric Ulcers, Helicobacter Pylori Infection

Additional Keywords : Increased Risk

Problem Substances : Aspirin

[+]

Aspirin use is associated with a higher rate of vitamin B12 deficiency in patients hospitalized with cardiovascular disease.Oct 01, 2004

Click here to read the entire abstract

Pubmed Data : Am J Cardiol. 2004 Oct 1;94(7):975-7. PMID: 15464695

Article Published Date : Oct 01, 2004

Study Type : Human Study

Additional Links

Diseases : Aspirin-Induced Toxicity , Drug-Induced Nutrient Depletion: Aspirin, Drug-Induced Nutrient Depletion: Vitamin B-12, Vitamin B 12 Deficiency

Pharmacological Actions : Platelet Aggregation Inhibitors

Additional Keywords : Aspirin-Vitamin b12 Deficiency, Drug-Nutrient Depletion

[+]

Decline of aspirin use is associated with a decreased incidence of Reye's syndrome.Jun 01, 1987

Click here to read the entire abstract

Pubmed Data : Pediatrics. 1987 Jun ;79(6):858-63. PMID: 3588140

Article Published Date : Jun 01, 1987

Study Type : Human Study

Additional Links

Diseases : Aspirin-Induced Toxicity , Encephalitis, Hepatitis

Problem Substances : Aspirin

[+]

Lactobacillus complex capsules ameliorate aspirin-related small intestinal mucosal injury: a prospective, randomized, controlled clinical trial.May 08, 2022

Click here to read the entire abstract

Pubmed Data : Scand J Gastroenterol. 2022 May 9:1-7. Epub 2022 May 9. PMID: 35534443

Article Published Date : May 08, 2022

Study Type : Human Study

Additional Links

Substances : Enterococcus faecium, Lactobacillus rhamnosus

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastroprotective

Problem Substances : Aspirin

[+]

Short-term administration of low-dose aspirin is associated with small bowel injuries and blood flow.Jan 14, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : World J Gastroenterol. 2011 Jan 14 ;17(2):226-30. PMID: 21245996

Article Published Date : Jan 14, 2011

Study Type : Human Study

Additional Links

Diseases : Aspirin-Induced Toxicity , Gastrointestinal Hemorrhage, NSAID-induced toxicity

Pharmacological Actions : Anti-Ulcer Agents

Problem Substances : Aspirin

[+]

Under hypoxic conditions, the presence of aspirin would not help to inhibit further platelet activation.May 01, 1999

Click here to read the entire abstract

Pubmed Data : Eur J Clin Invest. 1999 May;29(5):438-44. PMID: 10354201

Article Published Date : May 01, 1999

Study Type : Human Study

Additional Links

Diseases : Aspirin-Induced Toxicity , Hypoxia

Problem Substances : Aspirin

[+]

Vitamin C attenuates aspirin-induced gastric damage. May 01, 2009

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhen Jiu. 2009 May;29(5):382-4. PMID: 17218764

Article Published Date : May 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Aspirin-Induced Toxicity , NSAID-induced toxicity

Pharmacological Actions : Cyclooxygenase 2 Inhibitors

[+]

Yogurt containing Lactobacillus gasseri mitigates aspirin-induced small bowel injuries.Dec 31, 2016

Click here to read the entire abstract

Pubmed Data : Digestion. 2017 ;95(1):49-54. Epub 2017 Jan 5. PMID: 28052291

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Lactobacillus gasseri, Yoghurt

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastrointestinal Agents, Gastroprotective

Problem Substances : Aspirin

[+]

"Aspirin's ability to induce intestinal injury in rats is dependent on bile and can be reversed if pre-associated with phosphatidylcholine."Aug 01, 2011

Click here to read the entire abstract

Pubmed Data : J Physiol Pharmacol. 2011 Aug ;62(4):491-6. PMID: 22100851

Article Published Date : Aug 01, 2011

Study Type : Animal Study

Additional Links

Substances : Phosphatidylcholine

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastroprotective

Problem Substances : Aspirin

[+]

"ulforaphane Protects Small Intestinal Mucosa From Aspirin/NSAID-Induced Injury by Enhancing Host Defense Systems Against Oxidative Stress and by Inhibiting Mucosal Invasion of Anaerobic Enterobacteria."Aug 22, 2012

Click here to read the entire abstract

Pubmed Data : Curr Pharm Des. 2012 Aug 23. Epub 2012 Aug 23. PMID: 22950492

Article Published Date : Aug 22, 2012

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Aspirin-Induced Toxicity , NSAID-induced toxicity

[+]

A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions.Jun 01, 1999

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 1999 Jun;65(3):283-8. PMID: 10404428

Article Published Date : Jun 01, 1999

Study Type : Animal Study

Additional Links

Substances : Banana, Flavonoids

Diseases : Aspirin-Induced Toxicity , NSAID-induced toxicity

Pharmacological Actions : Anti-Ulcer Agents

[+]

Antipyretics increase influenza-associated mortality.Oct 01, 2010

Click here to read the entire abstract

Pubmed Data : J R Soc Med. 2010 Oct;103(10):403-11. PMID: 20929891

Article Published Date : Oct 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Acetaminophen (Tylenol) Toxicity , Aspirin-Induced Toxicity , Influenza, Influenza: Mortality

Problem Substances : Aspirin , Ibuprofen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Apple extracts assisted in protecting the gastric mucosa following acute aspirin administrationJul 27, 2014

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2014 Jul 28. Epub 2014 Jul 28. PMID: 25069887

Article Published Date : Jul 27, 2014

Study Type : Animal Study

Additional Links

Substances : Apple Polyphenols, Apples

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastroprotective

Additional Keywords : Plant Extracts

[+]

Artesunate affords protection against aspirin-induced gastric injury.Mar 31, 2018

Click here to read the entire abstract

Pubmed Data : Pharmacol Rep. 2018 Apr ;70(2):390-397. Epub 2017 Jun 15. PMID: 29397336

Article Published Date : Mar 31, 2018

Study Type : Animal Study

Additional Links

Substances : Artesunate

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Ulcer Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Aspirin

[+]

Astaxanthin protects against gastric ulcer formation. Dec 14, 2011

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2011 Dec 14. Epub 2011 Dec 14. PMID: 22170791

Article Published Date : Dec 14, 2011

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Alcohol Toxicity , Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective

[+]

Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.Nov 30, 2016

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2016 Dec ;41:47-55. Epub 2016 Nov 2. PMID: 27816726

Article Published Date : Nov 30, 2016

Study Type : Animal Study

Additional Links

Substances : Astragaloside

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Gastroprotective, Superoxide Dismutase Up-regulation

Problem Substances : Aspirin

[+]

Banana powder has anti-ulcerogenic properties.Oct 01, 1986

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 1986 Oct;18(1):33-44. PMID: 3821133

Article Published Date : Oct 01, 1986

Study Type : Animal Study

Additional Links

Substances : Banana

Diseases : Aspirin-Induced Toxicity , Corticosteroid-Induced Toxicity, Duodenal Ulcer, Gastric Ulcer, NSAID-induced toxicity

Pharmacological Actions : Anti-Ulcer Agents

[+]

Banana powder strengthens mucosal resistance and promotes the healing of ulcers.Sep 01, 1987

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 1987 Sep-Oct;21(1):11-9. PMID: 2447444

Article Published Date : Sep 01, 1987

Study Type : Animal Study

Additional Links

Substances : Banana

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer, Peptic Ulcer

Pharmacological Actions : Gastroprotective

[+]

Basil may be used as a nutritional supplement or therapeutic drug to protect against aspirin-induced gastric ulcers.Aug 14, 2018

Click here to read the entire abstract

Pubmed Data : Food Funct. 2018 Aug 15 ;9(8):4457-4468. PMID: 30073231

Article Published Date : Aug 14, 2018

Study Type : Animal Study

Additional Links

Substances : Basil

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastroprotective, Interleukin-6 Downregulation, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Aspirin

[+]

Cardamom has a gastroprotective effect in rats.Jan 16, 2006

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2006 Jan 16;103(2):149-53. Epub 2005 Nov 17. PMID: 16298093

Article Published Date : Jan 16, 2006

Study Type : Animal Study

Additional Links

Substances : Cardamom

Diseases : Alcohol Toxicity , Aspirin-Induced Toxicity , Gastric Ulcer, NSAID-induced toxicity

Pharmacological Actions : Anti-Ulcer Agents

[+]

Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury.Dec 24, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2020 Dec 25 ;134:111165. Epub 2020 Dec 25. PMID: 33370633

Article Published Date : Dec 24, 2020

Study Type : Animal Study

Additional Links

Substances : Panax Notoginseng

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastroprotective

Additional Keywords : Natural Substance/Drug Synergy

[+]

Combined Lycium babarum polysaccharides and C-phycocyanin increase gastric Bifidobacterium relative abundance and protect against gastric ulcer caused by aspirin.Jan 05, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Metab (Lond). 2021 Jan 6 ;18(1):4. Epub 2021 Jan 6. PMID: 33407626

Article Published Date : Jan 05, 2021

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Gastroprotective

Problem Substances : Aspirin

[+]

Drinking hydrogen-rich water may protect healthy individuals from gastric damage caused by oxidative stress.Mar 02, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2014 Mar 3 ;14:81. Epub 2014 Mar 3. PMID: 24589018

Article Published Date : Mar 02, 2014

Study Type : Animal Study

Additional Links

Substances : Hydrogen Water

Diseases : Aspirin-Induced Toxicity , Oxidative Stress

Pharmacological Actions : Antioxidants, Gastroprotective

Problem Substances : Aspirin

[+]

Effects of taxifolin on aspirin-induced gastric damage.Nov 08, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Anim. 2023 Nov 9 ;72(4):513-519. Epub 2023 Jun 19. PMID: 37331803

Article Published Date : Nov 08, 2023

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Antioxidants, Gastrointestinal Agents, Gastroprotective

Additional Keywords : Superiority of Natural Substances versus Drugs

Problem Substances : Aspirin

[+]

Fucoidan exhibits a gastro-protective effect against aspirin-induced ulceration in rats.Jan 31, 2011

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2011 Feb ;11(2):157-63. Epub 2010 Nov 26. PMID: 21084063

Article Published Date : Jan 31, 2011

Study Type : Animal Study

Additional Links

Substances : Fucoidan

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Anti-Ulcer Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Epidermal growth factor receptor (EGFR) inhibitor

Problem Substances : Aspirin

Adverse Pharmacological Actions : Ulcerogenic

[+]

Fucoidan has a protective effect against aspirin-induced stomach ulceration in rats. Jan 05, 2010

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2010 Jan 5;183(1):249-54. PMID: 19788892

Article Published Date : Jan 05, 2010

Study Type : Animal Study

Additional Links

Substances : Fucoidan

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Interleukin-6 Downregulation

[+]

Gastric mucosal protection by aegle marmelos against gastric mucosal damage.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saudi J Gastroenterol. 2015 Jan-Feb;21(1):35-42. PMID: 25672237

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Bael

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Gastroprotective

Additional Keywords : Plant Extracts

Problem Substances : Aspirin

[+]

Gastro-protective effect of methanol extract of Vernonia amygdalina leaf on aspirin-induced gastric ulcer.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Rep. 2017 ;4:625-633. Epub 2017 Nov 13. PMID: 29657922

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Mululuza

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Gastroprotective

Additional Keywords : Baganda Traditional Medicine

Problem Substances : Aspirin

[+]

Ginkgo biloba attenuates salicylate-induced tinnitus in rats.Jul 01, 1997

Click here to read the entire abstract

Pubmed Data : Audiol Neurootol. 1997 Jul-Aug;2(4):197-212. PMID: 9390833

Article Published Date : Jul 01, 1997

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba

Diseases : Aspirin-Induced Toxicity , Tinnitus

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Green mussel extract exhibits anti-inflammatory and gastroprotective properties.Jan 01, 1980

Click here to read the entire abstract

Pubmed Data : Arzneimittelforschung. 1980;30(12):2128-32. PMID: 7194074

Article Published Date : Jan 01, 1980

Study Type : Animal Study

Additional Links

Substances : Mussel: Green-lipped (Perna canaliculus)

Diseases : Aspirin-Induced Toxicity , Drug-Induced Toxicity: Indomethacin, Gastric Ulcer, NSAID-induced toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective

Additional Keywords : Drug: Indomethacin

[+]

Honey and a glucose-fructose-sucrose-maltose mixture against ethanol-, indomethacin-, and acidified aspirin-induced lesions in the rat.Nov 01, 2002

Click here to read the entire abstract

Pubmed Data : Exp Toxicol Pathol. 2002 Nov;54(3):217-21. PMID: 12484559

Article Published Date : Nov 01, 2002

Study Type : Animal Study

Additional Links

Substances : Fructose, Glucose, Honey, Maltose, Sucrose

Diseases : Alcohol Toxicity , Aspirin-Induced Toxicity , Gastric Ulcer, NSAID-induced toxicity

Pharmacological Actions : Gastroprotective

Additional Keywords : Drug: Indomethacin

[+]

Hydrogen rich water pre-treatment alleviated the aspirin-induced gastric lesions.Feb 13, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : World J Gastroenterol. 2014 Feb 14 ;20(6):1614-22. PMID: 24587639

Article Published Date : Feb 13, 2014

Study Type : Animal Study

Additional Links

Substances : Hydrogen Water

Diseases : Aspirin-Induced Toxicity , Gastrointestinal Inflammation, Oxidative Stress

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Gastroprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Aspirin

[+]

Lactobacillus casei protects against aspirin-induced small bowel injury. May 10, 2011

Click here to read the entire abstract

Pubmed Data : J Gastroenterol. 2011 May 10. Epub 2011 May 10. PMID: 21556830

Article Published Date : May 10, 2011

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei

Diseases : Aspirin-Induced Toxicity

[+]

Nigella Sativa extract has shown protective effects on kidneys against aspirin-induced damage.Dec 31, 2020

Click here to read the entire abstract

Pubmed Data : J Ayub Med Coll Abbottabad. 2021 Jan-Mar;33(1):39-43. PMID: 33774952

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Aspirin-Induced Toxicity , Kidney Damage: Drug-Induced

Pharmacological Actions : Renoprotective

Problem Substances : Aspirin

[+]

Nigella sativa has protective effect on aspirin-induced nephrotoxicity in rats.Sep 30, 2018

Click here to read the entire abstract

Pubmed Data : J Coll Physicians Surg Pak. 2018 Oct ;28(10):735-738. PMID: 30266114

Article Published Date : Sep 30, 2018

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Aspirin-Induced Toxicity , Kidney Damage: Drug-Induced

Pharmacological Actions : Renoprotective

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Aspirin

[+]

Palm vitamin E protects against alcohol-induced gastric injury in rats.Jan 01, 2000

Click here to read the entire abstract

Pubmed Data : Int J Food Sci Nutr. 2000;51 Suppl:S31-41. PMID: 11271855

Article Published Date : Jan 01, 2000

Study Type : Animal Study

Additional Links

Substances : Palm Tree, Vitamin E

Diseases : Alcohol Toxicity , Aspirin-Induced Toxicity , Gastric Ulcer, NSAID-induced toxicity

Pharmacological Actions : Anti-Ulcer Agents

[+]

Palm-derived vitamin E prevents aspirin-induced gastric lesions in rats. Mar 01, 2010

Click here to read the entire abstract

Pubmed Data : Acta Pol Pharm. 2010 Mar-Apr;67(2):179-84. PMID: 12657138

Article Published Date : Mar 01, 2010

Study Type : Animal Study

Additional Links

Substances : Palm Tree, Vitamin E

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer, NSAID-induced toxicity

Pharmacological Actions : Anti-Ulcer Agents

[+]

Photobiomodulation therapy in improvement of harmful neural plasticity in sodium salicylate-induced tinnitus.Dec 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2024 ;19(4):e0296607. Epub 2024 Apr 16. PMID: 38626075

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Diseases : Aspirin-Induced Toxicity , Tinnitus

Therapeutic Actions : Photobiomodulation

Problem Substances : Aspirin

[+]

Pomegranate extract protects against alcohol and aspirin-induced gastric mucosal injury.Jan 04, 2005

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2005 Jan 4;96(1-2):171-6. PMID: 15588667

Article Published Date : Jan 04, 2005

Study Type : Animal Study

Additional Links

Substances : Pomegranate

Diseases : Alcohol Toxicity , Aspirin-Induced Toxicity , Gastric Ulcer, NSAID-induced toxicity , Oxidative Stress

Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Gastroprotective

Additional Keywords : Plant Extracts

[+]

Promising effect of Geranium robertianum L. leaves and Aloe vera gel powder on aspirin-induced gastric ulcers.Nov 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Inflammopharmacology. 2023 Dec ;31(6):3183-3201. Epub 2023 May 15. PMID: 37184667

Article Published Date : Nov 30, 2023

Study Type : Animal Study

Additional Links

Substances : Aloe Vera, Geranium

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Antioxidants, Gastroprotective

Additional Keywords : Plant Extracts

Problem Substances : Aspirin

[+]

Protective effect of essential oil from Citrus limon against aspirin-induced toxicity.Dec 18, 2018

Click here to read the entire abstract

Pubmed Data : Hum Exp Toxicol. 2018 Dec 19:960327118819044. Epub 2018 Dec 19. PMID: 30565488

Article Published Date : Dec 18, 2018

Study Type : Animal Study

Additional Links

Substances : Lemon

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Antioxidants, Cytoprotective, Gastroprotective

Additional Keywords : Essential Oils

Problem Substances : Aspirin

[+]

Protective effects of dried mature Citrus unshiu peel (Chenpi) and hesperidin on aspirin-induced oxidative damage.Feb 28, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Biochem Nutr. 2021 Mar ;68(2):149-155. Epub 2020 Oct 13. PMID: 33879966

Article Published Date : Feb 28, 2021

Study Type : Animal Study

Additional Links

Substances : Hesperidin, Satsuma

Diseases : Aspirin-Induced Toxicity , Oxidative Stress

Pharmacological Actions : Antioxidants, Gastroprotective

Problem Substances : Aspirin

[+]

Protective effects of methanol extract of Vernonia amygdalina leaf on aspirin-induced gastric ulceration and oxidative mucosal damage.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Dose Response. 2018 ;16(3):1559325818785087. Epub 2018 Jul 8. PMID: 30013459

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Mululuza

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastroprotective

Additional Keywords : Baganda Traditional Medicine

Problem Substances : Aspirin

[+]

Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:314-321. Epub 2018 Nov 3. PMID: 30396089

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Spirulina

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Gastroprotective, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Aspirin

[+]

Spirulina supplements: an approach moderating aspirin persuaded histological and ultra-structural alterations in albino rats gastric mucosa.Mar 03, 2022

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Pubmed Data : Ultrastruct Pathol. 2022 Mar 4 ;46(2):204-216. PMID: 35333148

Article Published Date : Mar 03, 2022

Study Type : Animal Study

Additional Links

Substances : Spirulina

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Antioxidants, Gastrointestinal Agents, Gastroprotective

Problem Substances : Aspirin

[+]

Sulforaphane contributes to the protection of gastrointestinal mucosa against oxidative injury induced by H. pylori or NSAIDs.Feb 05, 2017

Click here to read the entire abstract

Pubmed Data : Curr Pharm Des. 2017 Feb 6. Epub 2017 Feb 6. PMID: 28176666

Article Published Date : Feb 05, 2017

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Aspirin-Induced Toxicity , Drug-Induced Toxicity: Indomethacin, Helicobacter Pylori Infection, NSAID-induced toxicity

Pharmacological Actions : Antioxidants

Problem Substances : Aspirin , Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

The administration of aspirin increases the retention of plutonium 238 in the skeleton of rats.Apr 01, 1983

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Pubmed Data : Radiat Res. 1983 Apr;94(1):89-96. PMID: 6856771

Article Published Date : Apr 01, 1983

Study Type : Animal Study

Additional Links

Diseases : Aspirin-Induced Toxicity , Radiation-Induced Illness: Plutonium

Additional Keywords : Problem Substance Synergy

Problem Substances : Aspirin , Plutonium 238

[+]

The efficacy of Musa paradisiaca in attenuating the damaging effects of aspirin on the gastric mucosa was observed in this study.Aug 14, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Open Access Maced J Med Sci. 2017 Aug 15 ;5(5):569-577. Epub 2017 Jul 26. PMID: 28932294

Article Published Date : Aug 14, 2017

Study Type : Animal Study

Additional Links

Substances : Banana

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastroprotective

[+]

The herbal extracts combination of turmeric, cardamom pods and sembung leaf has potential gastroprotective effects.Apr 30, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Trop Biomed. 2014 May ;4(Suppl 1):S500-4. PMID: 25183139

Article Published Date : Apr 30, 2014

Study Type : Animal Study

Additional Links

Substances : Cardamom, Sembung Leaf, Turmeric

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Gastroprotective

Additional Keywords : Plant Extracts

[+]

The protective effect of Citrus limon essential oil on hepatotoxicity and nephrotoxicity induced by aspirin.Sep 30, 2016

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Pubmed Data : Biomed Pharmacother. 2016 Oct ;83:1327-1334. Epub 2016 Aug 27. PMID: 27571876

Article Published Date : Sep 30, 2016

Study Type : Animal Study

Additional Links

Substances : Lemon

Diseases : Aspirin-Induced Toxicity , Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Essential Oils

Problem Substances : Aspirin

[+]

Tocotrienol-rich fraction and tocopherol prevent aspirin-induced gastric lesions.Jan 01, 2002

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Pubmed Data : Asia Pac J Clin Nutr. 2002;11(4):309-13. PMID: 12495264

Article Published Date : Jan 01, 2002

Study Type : Animal Study

Additional Links

Substances : Tocotrienols, Vitamin E

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer, Lipid Peroxidation

Pharmacological Actions : Antioxidants, Gastroprotective, Malondialdehyde Down-regulation

[+]

Treatment effects of Shilajit on aspirin-induced gastric lesionsMar 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Physiol Rep. 2021 Apr ;9(7):e14822. PMID: 33818003

Article Published Date : Mar 31, 2021

Study Type : Animal Study

Additional Links

Diseases : Aspirin-Induced Toxicity , Oxidative Stress

Pharmacological Actions : Antioxidants, Gastroprotective

Problem Substances : Aspirin

[+]

Vitamin E protects against gastric mucosal injury in rats.Mar 01, 2000

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Pubmed Data : Dig Dis Sci. 2000 Mar;45(3):599-605. PMID: 10749339

Article Published Date : Mar 01, 2000

Study Type : Animal Study

Additional Links

Substances : Vitamin E

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Gastroprotective

[+]

Zucchini has a protective effect against aspirin induced gastric and duodenal ulcer in rats. Sep 01, 2008

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Pubmed Data : Indian J Exp Biol. 2008 Sep;46(9):639-45. PMID: 18949893

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Zucchini

Diseases : Aspirin-Induced Toxicity , Duodenal Ulcer, Gastric Ulcer, Gastroduodenal Ulcer

Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective

Additional Keywords : Plant Extracts

Problem Substances : Aspirin

[+]

C-Phycocyanin and Lycium barbarum polysaccharides protect against aspirin-induced Inflammation and apoptosis.Nov 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2022 Dec 1 ;14(23). Epub 2022 Dec 1. PMID: 36501143

Article Published Date : Nov 30, 2022

Study Type : In Vitro Study

Additional Links

Substances : Goji

Diseases : Aspirin-Induced Toxicity , Inflammation

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Gastroprotective, Interleukin-10 upregulation

Additional Keywords : Polysaccharides

Problem Substances : Aspirin

[+]

Gastric protective activities of fucoidan from brown alga Kjellmaniella crassifolia through the NF-κB signaling pathway.Jan 19, 2020

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Pubmed Data : Int J Biol Macromol. 2020 Jan 20. Epub 2020 Jan 20. PMID: 31972198

Article Published Date : Jan 19, 2020

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan

Diseases : Aspirin-Induced Toxicity , Gastric Ulcer

Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Aspirin

[+]

HLA-related and other genetic markers involved in severe hypersensitivity reactions to aspirin and other drugsJul 31, 2010

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Pubmed Data : Curr Opin Allergy Clin Immunol. 2010 Aug ;10(4):280-90. PMID: 20485159

Article Published Date : Jul 31, 2010

Study Type : Review

Additional Links

Diseases : Aspirin-Induced Toxicity , Drug-Induced Toxicity , Hypersensitivity

Problem Substances : Allopurinol, Antibiotics, Aspirin

[+]

Protective effects of essential oil of Citrus limon against aspirin-induced toxicity in IEC-6 cells.Apr 30, 2017

Click here to read the entire abstract

Pubmed Data : Appl Physiol Nutr Metab. 2017 May ;42(5):479-486. Epub 2016 Dec 15. PMID: 28177735

Article Published Date : Apr 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Lemon

Diseases : Aspirin-Induced Toxicity

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Essential Oils

Problem Substances : Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

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View the Evidence: 58 Abstracts with Aspirin-Induced Toxicity Research

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This analysis suggests Helicobacter pylori increases the risk of low-dose aspirin ulcers.Nov 07, 2018

Aspirin use is associated with a higher rate of vitamin B12 deficiency in patients hospitalized with cardiovascular disease.Oct 01, 2004

Decline of aspirin use is associated with a decreased incidence of Reye's syndrome.Jun 01, 1987

Lactobacillus complex capsules ameliorate aspirin-related small intestinal mucosal injury: a prospective, randomized, controlled clinical trial.May 08, 2022

Short-term administration of low-dose aspirin is associated with small bowel injuries and blood flow.Jan 14, 2011

Under hypoxic conditions, the presence of aspirin would not help to inhibit further platelet activation.May 01, 1999

Vitamin C attenuates aspirin-induced gastric damage. May 01, 2009

Yogurt containing Lactobacillus gasseri mitigates aspirin-induced small bowel injuries.Dec 31, 2016

"Aspirin's ability to induce intestinal injury in rats is dependent on bile and can be reversed if pre-associated with phosphatidylcholine."Aug 01, 2011

"ulforaphane Protects Small Intestinal Mucosa From Aspirin/NSAID-Induced Injury by Enhancing Host Defense Systems Against Oxidative Stress and by Inhibiting Mucosal Invasion of Anaerobic Enterobacteria."Aug 22, 2012

A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions.Jun 01, 1999

Antipyretics increase influenza-associated mortality.Oct 01, 2010

Apple extracts assisted in protecting the gastric mucosa following acute aspirin administrationJul 27, 2014

Artesunate affords protection against aspirin-induced gastric injury.Mar 31, 2018

Astaxanthin protects against gastric ulcer formation. Dec 14, 2011

Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.Nov 30, 2016

Banana powder has anti-ulcerogenic properties.Oct 01, 1986

Banana powder strengthens mucosal resistance and promotes the healing of ulcers.Sep 01, 1987

Basil may be used as a nutritional supplement or therapeutic drug to protect against aspirin-induced gastric ulcers.Aug 14, 2018

Cardamom has a gastroprotective effect in rats.Jan 16, 2006

Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury.Dec 24, 2020

Combined Lycium babarum polysaccharides and C-phycocyanin increase gastric Bifidobacterium relative abundance and protect against gastric ulcer caused by aspirin.Jan 05, 2021

Drinking hydrogen-rich water may protect healthy individuals from gastric damage caused by oxidative stress.Mar 02, 2014

Effects of taxifolin on aspirin-induced gastric damage.Nov 08, 2023

Fucoidan exhibits a gastro-protective effect against aspirin-induced ulceration in rats.Jan 31, 2011

Fucoidan has a protective effect against aspirin-induced stomach ulceration in rats. Jan 05, 2010

Gastric mucosal protection by aegle marmelos against gastric mucosal damage.Dec 31, 2014

Gastro-protective effect of methanol extract of Vernonia amygdalina leaf on aspirin-induced gastric ulcer.Dec 31, 2016

Ginkgo biloba attenuates salicylate-induced tinnitus in rats.Jul 01, 1997

Green mussel extract exhibits anti-inflammatory and gastroprotective properties.Jan 01, 1980

Honey and a glucose-fructose-sucrose-maltose mixture against ethanol-, indomethacin-, and acidified aspirin-induced lesions in the rat.Nov 01, 2002

Hydrogen rich water pre-treatment alleviated the aspirin-induced gastric lesions.Feb 13, 2014

Lactobacillus casei protects against aspirin-induced small bowel injury. May 10, 2011

Nigella Sativa extract has shown protective effects on kidneys against aspirin-induced damage.Dec 31, 2020

Nigella sativa has protective effect on aspirin-induced nephrotoxicity in rats.Sep 30, 2018

Palm vitamin E protects against alcohol-induced gastric injury in rats.Jan 01, 2000

Palm-derived vitamin E prevents aspirin-induced gastric lesions in rats. Mar 01, 2010

Photobiomodulation therapy in improvement of harmful neural plasticity in sodium salicylate-induced tinnitus.Dec 31, 2023

Pomegranate extract protects against alcohol and aspirin-induced gastric mucosal injury.Jan 04, 2005

Promising effect of Geranium robertianum L. leaves and Aloe vera gel powder on aspirin-induced gastric ulcers.Nov 30, 2023

Protective effect of essential oil from Citrus limon against aspirin-induced toxicity.Dec 18, 2018

Protective effects of dried mature Citrus unshiu peel (Chenpi) and hesperidin on aspirin-induced oxidative damage.Feb 28, 2021

Protective effects of methanol extract of Vernonia amygdalina leaf on aspirin-induced gastric ulceration and oxidative mucosal damage.Dec 31, 2017

Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation.Dec 31, 2018

Spirulina supplements: an approach moderating aspirin persuaded histological and ultra-structural alterations in albino rats gastric mucosa.Mar 03, 2022

Sulforaphane contributes to the protection of gastrointestinal mucosa against oxidative injury induced by H. pylori or NSAIDs.Feb 05, 2017

The administration of aspirin increases the retention of plutonium 238 in the skeleton of rats.Apr 01, 1983

The efficacy of Musa paradisiaca in attenuating the damaging effects of aspirin on the gastric mucosa was observed in this study.Aug 14, 2017

The herbal extracts combination of turmeric, cardamom pods and sembung leaf has potential gastroprotective effects.Apr 30, 2014

The protective effect of Citrus limon essential oil on hepatotoxicity and nephrotoxicity induced by aspirin.Sep 30, 2016

Tocotrienol-rich fraction and tocopherol prevent aspirin-induced gastric lesions.Jan 01, 2002

Treatment effects of Shilajit on aspirin-induced gastric lesionsMar 31, 2021

Vitamin E protects against gastric mucosal injury in rats.Mar 01, 2000

Zucchini has a protective effect against aspirin induced gastric and duodenal ulcer in rats. Sep 01, 2008

C-Phycocyanin and Lycium barbarum polysaccharides protect against aspirin-induced Inflammation and apoptosis.Nov 30, 2022

Gastric protective activities of fucoidan from brown alga Kjellmaniella crassifolia through the NF-κB signaling pathway.Jan 19, 2020

HLA-related and other genetic markers involved in severe hypersensitivity reactions to aspirin and other drugsJul 31, 2010

Protective effects of essential oil of Citrus limon against aspirin-induced toxicity in IEC-6 cells.Apr 30, 2017

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Aspirin-Induced Toxicity

View the Evidence:
58 Abstracts with Aspirin-Induced Toxicity Research