Bile Duct Injury

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1 Substances Researched for Bile Duct Injury
NameACCKFocus
Melatonin12Locked
2 Problem Substances Researched for Bile Duct Injury
NameACCKFocus
Atorvastatin26Locked
Statin Drugs13Locked

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3 Abstracts with Bile Duct Injury Research

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A case of atorvastatin-induced prolonged cholestasis with bile duct damage has been reported.Jan 01, 2010

Pubmed Data : Clin Drug Investig. 2010 ;30(3):205-9. PMID: 20155993
Article Published Date : Jan 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Alkaline Phosphatase: Elevated, Bile Duct Injury, Bilirubin: Elevated, Cholangiolitis, Cholestasis, Hepatitis: Cholestatic, Statin-Induced Pathologies
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Atorvastatin
[+]

Atorvastatin has been reported to have caused severe acute hepatitis with symptomatic cholestasis for more than 3 months and bile duct injury. Jul 01, 2008

Pubmed Data : Acta Gastroenterol Belg. 2008 Jul-Sep;71(3):318-20. PMID: 19198578
Article Published Date : Jul 01, 2008
Study Type : Human: Case Report
Additional Links
Diseases : Bile Duct Injury, Chemically-Induced Liver Damage, Cholestasis, Statin-Induced Pathologies
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Atorvastatin, Statin Drugs
Adverse Pharmacological Actions : Hepatotoxic
[+]

Melatonin rescued the apoptotic changes via the intrinsic pathway.Dec 31, 2015

Pubmed Data : Int J Mol Sci. 2016;17(8). Epub 2016 Aug 20. PMID: 27556445
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Bile Duct Injury
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective

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