Birth Defects

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11 Substances Researched for Birth Defects
NameACCKFocus
B-complex120Locked
Vitamin A110Locked
Water110Locked
Potato24Locked
Resveratrol24Locked
Solanum Species24Locked
Echinacea12Locked
Eggplant12Locked
Folic Acid 12Locked
Ginseng (Siberian)12Locked
Tomato12Locked
36 Problem Substances Researched for Birth Defects
NameACCKFocus
Statin Drugs622Locked
Angiotensin-Converting Enzyme (ACE) Inhibitor 220Locked
Antidepressants220Locked
Retinyl palmitate314Locked
Mercury211Locked
Angiotensin Receptor Blockers (ARBs)110Locked
Antihypertensive Drugs110Locked
Atorvastatin110Locked
Dental Amalgams110Locked
Diphenhydramine110Locked
Fluoxetine (trade name Prozac) 110Locked
Selective Serotonin Reuptake Inhibitors (SSRIs)110Locked
Sugar Sweetened Beverages110Locked
Tricyclic Antidepressant (TCA) 110Locked
Uranium: Depleted110Locked
Lovastatin28Locked
Cell Phone Exposure24Locked
Letrozole (trade name Femera)24Locked
Bisphenol A 23Locked
Methotrexate13Locked
2,4-Dichlorophenoxyacetic acid12Locked
Arsenic12Locked
Fluoride12Locked
Polystyrene nanoparticles12Locked
Potato12Locked
Retinyl Acetate12Locked
Sodium Selenate12Locked
Sodium Selenite12Locked
Solanum Species12Locked
Spirosolane12Locked
Vitamin A acetate12Locked
Vitamin A palmitate12Locked
17beta-estradiol11Locked
Diethylstilbestrol (DES)11Locked
Pesticides11Locked
Radioiodine 13111Locked
1 Therapeutic Actions Researched for Birth Defects
NameACCKFocus
Photobiomodulation220Locked
8 Problematic Actions Researched for Birth Defects
NameACCKFocus
Vaccination: All330Locked
Electromagnetic Field Harms526Locked
Electromagnetic Radiation526Locked
Vaccination: Adult Rubella110Locked
Vaccination: Anthrax110Locked
Vaccination: Diphtheria-Pertussis-Tetanus110Locked
Microwave Radiation24Locked
Mobile Phone Radiation24Locked

View the Evidence:
54 Abstracts with Birth Defects Research

[+]

Periconceptional folate supplementation prevents birth defects.Jan 01, 2010

Pubmed Data : Cochrane Database Syst Rev. 2010(10):CD007950. Epub 2010 Oct 6. PMID: 20927767
Article Published Date : Jan 01, 2010
Study Type : Meta Analysis
Additional Links
Substances : B-complex
Diseases : Birth Defects, Prenatal Nutrition , Prenatal Nutrition: Prevention of Problems
[+]

In the offspring of fathers most likely to have been exposed to radiofrequency electromagnetic fields, there was an increased risk for preterm birth and a category of "other defects. Researchers also observed a decreased risk of certain other defects.Jan 01, 2006

Pubmed Data : Eur J Epidemiol. 2006 ;21(7):529-35. Epub 2006 Jul 21. PMID: 16858619
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Additional Keywords : EMF, Pregnancy, Pregnancy And Fetal Growth
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
[+]

Antidepressant drugs are associated with birth defects. Jan 05, 2010

Pubmed Data : Psychol Med. 2010 Jan 5:1-11. Epub 2010 Jan 5. PMID: 20047705
Article Published Date : Jan 05, 2010
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Problem Substances : Antidepressants, Tricyclic Antidepressant (TCA)
[+]

Antidepressants such as the SSRI paroxetine are associated with birth defects. Dec 01, 2006

Pubmed Data : Prescrire Int. 2006 Dec;15(86):222-3. PMID: 17167929
Article Published Date : Dec 01, 2006
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Problem Substances : Antidepressants, Selective Serotonin Reuptake Inhibitors (SSRIs)
[+]

Birth defects are more common in pregnant women who received the anthrax vaccine during their first trimester versus later in pregnancy. Aug 15, 2008

Pubmed Data : Am J Epidemiol. 2008 Aug 15 ;168(4):434-42. Epub 2008 Jul 2. PMID: 18599489
Article Published Date : Aug 15, 2008
Study Type : Human Study
Additional Links
Diseases : Anthrax, Birth Defects, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Anthrax
Adverse Pharmacological Actions : Teratogenic
[+]

Congenital malformation is a possible consequence of rubella vaccination during pregnancy.Sep 25, 1981

Pubmed Data : JAMA. 1981 Sep 25;246(13):1413-7. PMID: 7265443
Article Published Date : Sep 25, 1981
Study Type : Human Study
Additional Links
Diseases : Birth Defects, Pregnancy: Vaccination, Rubella, Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Adult Rubella, Vaccination: All
[+]

Diphenhydramine (Benadryl) use during early pregnancy may be associated with increased risk for birth defects. Feb 01, 2009

Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2009 Feb;85(2):137-50. PMID: 19161158
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Problem Substances : Diphenhydramine
[+]

Evaluation of atorvastatin efficacy and toxicity on spermatozoa, accessory glands and gonadal hormones of healthy men: a pilot prospective clinical trial.Jul 11, 2014

Pubmed Data : Reprod Biol Endocrinol. 2014 Jul 12 ;12(1):65. Epub 2014 Jul 12. PMID: 25016482
Article Published Date : Jul 11, 2014
Study Type : Human Study
Additional Links
Diseases : Birth Defects, Infertility: Male, Sperm Count: Low, Sperm Quality: Low
Problem Substances : Atorvastatin
Adverse Pharmacological Actions : Teratogenic
[+]

Exposure to ACE inhibitors during the first trimester increases the risk of major congenital malformations.Jun 08, 2006

Pubmed Data : N Engl J Med. 2006 Jun 8;354(23):2443-51. PMID: 16760444
Article Published Date : Jun 08, 2006
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Problem Substances : Angiotensin-Converting Enzyme (ACE) Inhibitor
[+]

First-trimester exposure to fluoxetine is associated with cardiovascular abnormalities. Nov 01, 2008

Pubmed Data : Br J Clin Pharmacol. 2008 Nov;66(5):695-705. Epub 2008 Jul 11. PMID: 18754846
Article Published Date : Nov 01, 2008
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Problem Substances : Fluoxetine (trade name Prozac)
[+]

Gestational exposure to paroxetine is associated with major congenital malformations and major cardiac malformations for only first trimester exposure above 25 mg/day.Feb 01, 2007

Pubmed Data : Birth Defects Res B Dev Reprod Toxicol. 2007 Feb;80(1):18-27. PMID: 17187388
Article Published Date : Feb 01, 2007
Study Type : Human Study
Additional Links
Diseases : Birth Defects
[+]

High dietary intake of preformed vitamin A appears to be teratogenic. Among the babies born to women who took more than 10,000 IU of preformed vitamin A per day in the form of supplements, we estimate that about 1 infant in 57 had a malformation attributaNov 23, 1995

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Engl J Med. 1995 Nov 23 ;333(21):1369-73. PMID: 7477116
Article Published Date : Nov 23, 1995
Study Type : Human Study
Additional Links
Substances : Vitamin A
Diseases : Abnormalities, Birth Defects, Drug-Induced, Prenatal Nutrition: Prevention of Problems
Problem Substances : Retinyl palmitate
Adverse Pharmacological Actions : Teratogenic
[+]

Human epidemiological evidence is consistent with increased risk of birth defects in offspring of persons exposed to depleted uranium.Jan 01, 2005

Pubmed Data : Environ Health. 2005;4:17. Epub 2005 Aug 26. PMID: 16124873
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Problem Substances : Uranium: Depleted
Adverse Pharmacological Actions : Teratogenic
[+]

Novel treatment immediately after myelomeningocele repair applying low-level laser therapy in newborns.Dec 31, 2009

Pubmed Data : Pediatr Neurosurg. 2010 ;46(4):249-54. Epub 2010 Dec 15. PMID: 21160232
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Diseases : Birth Defects, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Pilot study in neonates using low-level laser therapy in the immediate postoperative period of myelomeningocele.Feb 28, 2010

Pubmed Data : Einstein (Sao Paulo). 2010 Mar ;8(1):5-9. PMID: 26761745
Article Published Date : Feb 28, 2010
Study Type : Human Study
Additional Links
Diseases : Birth Defects, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Risk documentation occured in only 20% of women age 15-45 prescribed a medication known to contribute to birth defects. May 01, 2011

Pubmed Data : J Am Board Fam Med. 2011 May-Jun;24(3):262-71. PMID: 21551398
Article Published Date : May 01, 2011
Study Type : Human Study
Additional Links
Diseases : Birth Defects, Drug-Induced Toxicity , Statin-Induced Pathologies
Problem Substances : Angiotensin-Converting Enzyme (ACE) Inhibitor , Angiotensin Receptor Blockers (ARBs), Statin Drugs
Adverse Pharmacological Actions : Teratogenic
[+]

Service aboard a Norwegian missile torpedo speed boat was associated with an increased risk of having children with congenital birth defects and having children that were stillborn. The investigation of the ship included measurements of high‐frequency EMFFeb 01, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Occup Environ Med. 2006 Feb ;63(2):92-7. PMID: 16421386
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Additional Keywords : EMF, Pregnancy, Pregnancy And Fetal Growth
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
[+]

Severity of autism may correlated with the number of maternal dental amalgams.Jan 01, 2009

Pubmed Data : Acta Neurobiol Exp (Wars). 2009 ;69(2):189-97. PMID: 19593333
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Autism, Autism Spectrum Disorders, Birth Defects
Additional Keywords : Heavy Metals and Autism, Pregnancy, Pregnancy And Fetal Growth
Problem Substances : Dental Amalgams, Mercury
Adverse Pharmacological Actions : Neurotoxic
[+]

The maternal use of antihypertensives is associated with an increased risk for infant cardiovascular defects.Jun 01, 2009

Pubmed Data : Eur J Clin Pharmacol. 2009 Jun;65(6):615-25. Epub 2009 Feb 7. PMID: 19198819
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Birth Defects
Problem Substances : Antihypertensive Drugs
[+]

There were many cases of microcephaly reported in 2014, attributed to the Brazil Zika outbreak, however, this outbreak also overlapped with Brazil's initiation of their Tdap program.Nov 01, 2016

Pubmed Data : JAMA. 2016 Nov 1 ;316(17):1823-1825. PMID: 27802536
Article Published Date : Nov 01, 2016
Study Type : Human Study
Additional Links
Diseases : Birth Defects, Microcephaly, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus
[+]

These results observed decreases in estimated risks associated with increases in water consumption for several birth defects. Oct 20, 2016

Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2016 Oct 21. Epub 2016 Aug 21. PMID: 27768247
Article Published Date : Oct 20, 2016
Study Type : Human Study
Additional Links
Substances : Water
Diseases : Birth Defects, Spina Bifida
Additional Keywords : Risk Factors, Risk Reduction
Problem Substances : Sugar Sweetened Beverages
[+]

Lovastatin exhibits toxicity in human fetal brain cells.Jan 01, 1995

Pubmed Data : Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID: 7708017
Article Published Date : Jan 01, 1995
Study Type : Human In Vitro
Additional Links
Diseases : Abortion: Spontaneous, Birth Defects, Neurotoxicity, Prenatal Chemical Exposures
Pharmacological Actions : Antiproliferative
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Neurotoxic, Teratogenic
[+]

Central nervous system and limb anomalies have been reported in first-trimester statin exposure.Apr 08, 2004

Pubmed Data : N Engl J Med. 2004 Apr 8 ;350(15):1579-82. PMID: 15071140
Article Published Date : Apr 08, 2004
Study Type : Human: Case Report
Additional Links
Diseases : Birth Defects, Pregnancy: Environmental Exposures, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Teratogenic
[+]

Gestational exposure to lovastatin followed by cardiac malformation misclassified as holoprosencephaly has been reported. Jun 30, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Engl J Med. 2005 Jun 30 ;352(26):2759. PMID: 15987932
Article Published Date : Jun 30, 2005
Study Type : Human: Case Report
Additional Links
Diseases : Birth Defects, Pregnancy: Environmental Exposures, Statin-Induced Pathologies
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Teratogenic
[+]

High-dose methotrexate during pregnancy is associated malformations. Oct 01, 2010

Pubmed Data : Prescrire Int. 2010 Oct;19(109):212-3. PMID: 21180376
Article Published Date : Oct 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Birth Defects, Cardiomyopathy, Drug Toxicity: Methotrexate, Prenatal Chemical Exposures, Scoliosis
Problem Substances : Methotrexate
Adverse Pharmacological Actions : Teratogenic
[+]

"According to US EPA, 2,4-D in agricultural scenarios may be up to three times higher than the NOEC values for teratogenic effects reported in this study. "Aug 01, 2011

Pubmed Data : Environ Toxicol. 2011 Aug ;26(4):373-81. Epub 2010 Jan 28. PMID: 20112415
Article Published Date : Aug 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Birth Defects
Adverse Pharmacological Actions : Teratogenic
[+]

"Teratogenic effects of chronic ingestion of high levels of vitamin A (retinyl acetate) in cats."Feb 01, 2003

Pubmed Data : J Anim Physiol Anim Nutr (Berl). 2003 Feb ;87(1-2):42-51. PMID: 14511148
Article Published Date : Feb 01, 2003
Study Type : Animal Study
Additional Links
Diseases : Birth Defects
Problem Substances : Retinyl Acetate
Adverse Pharmacological Actions : Teratogenic
[+]

Adverse effects were observed as a result of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant mice.Jan 01, 2003

Pubmed Data : Food Chem Toxicol. 2003 Jan ;41(1):61-71. PMID: 12453729
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Eggplant, Potato, Solanum Species, Tomato
Diseases : Birth Defects, Hepatomegaly, Infertility, Miscarriage
Adverse Pharmacological Actions : Abortive, Teratogenic
[+]

Bisphenol A is associated with birth defects and inhibition of normal embryonic development in an animal model. Sep 01, 2003

Pubmed Data : Gen Comp Endocrinol. 2003 Sep;133(2):189-98. PMID: 12928009
Article Published Date : Sep 01, 2003
Study Type : Animal Study
Additional Links
Diseases : Birth Defects
Problem Substances : Bisphenol A
[+]

Drugs targeting cholesterol synthesis are embryo lethal in mice and likely contribute to birth defects in humans. Feb 01, 2011

Pubmed Data : Drug Metab Rev. 2011 Feb ;43(1):69-90. PMID: 21247357
Article Published Date : Feb 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Infant Mortality , Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Teratogenic
[+]

Echinacea can stimulate immune system more than levamisole and has better prophylactic effect on incidence of phenytoin-induced cleft palate.Dec 01, 2006

Pubmed Data : Regul Toxicol Pharmacol. 2006 Dec;46(3):163-6. Epub 2006 Aug 4. PMID: 16889880
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Birth Defects, Cleft Lip, Immune Disorders: Low Immune Function
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Gestational exposure to doses of letrozole that are equal to or lower than the daily recommended human dose has toxic effects on prenatal development in rats.Aug 01, 2008

Pubmed Data : Hum Reprod. 2008 Aug;23(8):1719-23. Epub 2008 May 15. PMID: 18487213
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Drug-Induced Toxicity , Prenatal Chemical Exposures
Problem Substances : Letrozole (trade name Femera)
Adverse Pharmacological Actions : Embryotoxic, Teratogenic
[+]

High dose vitamin A palmitate results in fused carpal bone defects in rat fetuses.Jun 01, 2010

Pubmed Data : Hum Exp Toxicol. 2010 Jun;29(6):439-50. Epub 2010 Mar 17. PMID: 20237176
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Prenatal Chemical Exposures
Problem Substances : Vitamin A palmitate
Adverse Pharmacological Actions : Teratogenic
[+]

Intermittent mobile phone exposure results in a significant increase in embryonic mortality and cardiac deformity in chicken embryos.Jun 01, 2016

Pubmed Data : Anat Histol Embryol. 2016 Jun ;45(3):197-208. Epub 2015 Jul 14. PMID: 26171674
Article Published Date : Jun 01, 2016
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, DNA damage
Additional Keywords : Cell Phones, electromagnetic radiation, EMF, Pregnancy, Pregnancy And Fetal Growth
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Abortive, Cardiotoxic, Genotoxic
[+]

Letrozole has a toxic effect on the embryos of rats. Nov 01, 2009

Pubmed Data : Hum Reprod. 2009 Nov;24(11):2688-92. Epub 2009 Jul 27. PMID: 19638353
Article Published Date : Nov 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Birth Defects, Prenatal Chemical Exposures
Problem Substances : Letrozole (trade name Femera)
Adverse Pharmacological Actions : Embryotoxic, Teratogenic
[+]

Low doses of vitamin A (retinyl acetate) result in defects in offspring of animals and perhaps humans when consumed during the early gestational period.Oct 01, 2000

Pubmed Data : Teratology. 2000 Oct;62(4):214-26. PMID: 10992263
Article Published Date : Oct 01, 2000
Study Type : Animal Study
Additional Links
Diseases : Birth Defects
Problem Substances : Vitamin A acetate
Adverse Pharmacological Actions : Teratogenic
[+]

Low levels of selenium, fluoride and arsenic are toxic to rat embryos.Mar 30, 1999

Pubmed Data : Wei Sheng Yan Jiu. 1999 Mar 30;28(2):74-6. PMID: 11939006
Article Published Date : Mar 30, 1999
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Prenatal Chemical Exposures
Additional Keywords : Drug Synergy
Problem Substances : Arsenic, Fluoride, Sodium Selenate, Sodium Selenite
Adverse Pharmacological Actions : Teratogenic
[+]

Nanoplastics causes extensive congenital malformations during embryonic development by passively targeting neural crest cells.Feb 28, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2023 Mar ;173:107865. Epub 2023 Mar 6. PMID: 36907039
Article Published Date : Feb 28, 2023
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Cardiotoxic
[+]

Prenatal administration of Eleutherococcus abolishes the embryotoxic and teratogenic effects of ethanol.Jan 01, 1993

Pubmed Data : Ontogenez. 1993 Jan-Feb;24(1):48-55. PMID: 8474760
Article Published Date : Jan 01, 1993
Study Type : Animal Study
Additional Links
Substances : Ginseng (Siberian)
Diseases : Alcohol Toxicity , Birth Defects, Prenatal Chemical Exposures
[+]

Rats born to mothers exposed to mobile phone radiation exhibit altered electrophysiological properties of CA1 pyramidal neurons, deleteriously impacting cognition.Jun 01, 2016

Pubmed Data : Toxicol Ind Health. 2016 Jun ;32(6):968-79. Epub 2014 Mar 6. PMID: 24604340
Article Published Date : Jun 01, 2016
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Cognitive Decline/Dysfunction, Learning disorders
Additional Keywords : electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF, Pregnancy, Pregnancy And Fetal Growth
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Neurotoxic
[+]

Resveratrol prevents chemically-induced prenatal defects in miceSep 04, 2008

Pubmed Data : Eur J Pharmacol. 2008 Sep 4;591(1-3):280-3. Epub 2008 May 28. PMID: 18571640
Article Published Date : Sep 04, 2008
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Birth Defects, Prenatal Chemical Exposures
Additional Keywords : Stilbenes
[+]

Retinyl palmitate exhibits teratrogenic properties. Dec 01, 2009

Pubmed Data : Indian J Exp Biol. 2009 Dec ;47(12):949-54. PMID: 20329697
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Prenatal Chemical Exposures
Problem Substances : Retinyl palmitate
Adverse Pharmacological Actions : Teratogenic
[+]

Retinyl palmitate induces malformations in the embryos of pregnant rats.Sep 01, 1996

Pubmed Data : Pharmacol Toxicol. 1996 Sep;79(3):131-5. PMID: 8884871
Article Published Date : Sep 01, 1996
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Prenatal Chemical Exposures
Problem Substances : Retinyl palmitate
Adverse Pharmacological Actions : Teratogenic
[+]

Spirosolane-containing Solanum species are capable of inducing congenital craniofacial malformations.Jan 01, 1990

Pubmed Data : Toxicon. 1990 ;28(8):873-84. PMID: 2080514
Article Published Date : Jan 01, 1990
Study Type : Animal Study
Additional Links
Substances : Potato, Solanum Species
Diseases : Birth Defects
Problem Substances : Potato, Solanum Species, Spirosolane
Adverse Pharmacological Actions : Teratogenic
[+]

Statin drugs cause early embryo lethality in animals. Oct 31, 2003

Pubmed Data : J Biol Chem. 2003 Oct 31 ;278(44):42936-41. Epub 2003 Aug 14. PMID: 12920113
Article Published Date : Oct 31, 2003
Study Type : Animal Study
Additional Links
Diseases : Birth Defects
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Teratogenic
[+]

Statin drugs have been shown to cause adverse effects in pregnant rats and their offspring, including fetal death. Oct 17, 2011

Pubmed Data : Birth Defects Res B Dev Reprod Toxicol. 2011 Oct 17. Epub 2011 Oct 17. PMID: 22006546
Article Published Date : Oct 17, 2011
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Birth Defects, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Teratogenic
[+]

Synergistic protective effects of folic acid and resveratrol against fine particulate matter-induced heart malformations in zebrafish embryos.Jul 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2022 Aug ;241:113825. Epub 2022 Jun 29. PMID: 36068752
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Folic Acid , Resveratrol
Diseases : Air Pollution Linked Toxicity, Birth Defects
Pharmacological Actions : Antioxidants
Additional Keywords : Natural Substance Synergy
[+]

The diethylamine salt of 2,4-D exhibits embryotoxic actions. Feb 01, 1973

Pubmed Data : Gig Sanit. 1973 Feb ;38(2):100-1. PMID: 4779861
Article Published Date : Feb 01, 1973
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, Miscarriage
Problem Substances : 2,4-Dichlorophenoxyacetic acid
Adverse Pharmacological Actions : Embryotoxic
[+]

This study demonstrated the ability of extremely-low electromagnetic fields to impact fetal development in a tissue-specific way.Jan 01, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(11):e0142259. Epub 2015 Nov 11. PMID: 26559811
Article Published Date : Jan 01, 2015
Study Type : Animal Study
Additional Links
Diseases : Birth Defects, DNA damage
Additional Keywords : Pregnancy And Fetal Growth, Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation
Adverse Pharmacological Actions : Genotoxic, Oxidant
[+]

A review and update of human exposure and toxicity of pesticides. Jan 31, 2017

Pubmed Data : Arch Toxicol. 2017 Feb ;91(2):549-599. Epub 2016 Oct 8. PMID: 27722929
Article Published Date : Jan 31, 2017
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Asthma, Attention Deficit Hyperactivity Disorder, Autism, Birth Defects, Bronchitis, Infertility, Obesity, Parkinson's Disease, Pesticide Toxicity
Additional Keywords : Risk Factors
Problem Substances : Pesticides
Adverse Pharmacological Actions : Neurotoxic
[+]

Animal studies demonstrate a link between maternal immune activation and autism spectrum disorder in offspring.Jan 01, 2018

Pubmed Data : Exp Neurol. 2018 01 ;299(Pt A):241-251. Epub 2017 Jul 8. PMID: 28698032
Article Published Date : Jan 01, 2018
Study Type : Review
Additional Links
Diseases : Autism, Autism Spectrum Disorders, Birth Defects, Brain: Microglial Activation
Additional Keywords : Vaccine Research
[+]

Bisphenol A, Diethylstilbestrol (DES), and 17beta-estradiol have chromosome-damaging potential. Jan 08, 2008

Pubmed Data : Mutat Res. 2008 Jan 8;649(1-2):114-25. Epub 2007 Aug 19. PMID: 17913570
Article Published Date : Jan 08, 2008
Study Type : In Vitro Study
Additional Links
Diseases : Birth Defects, DNA damage
Problem Substances : 17beta-estradiol, Bisphenol A , Diethylstilbestrol (DES)
[+]

Fetal exposure to radioiodine may result in major malformations, thyroid dysfunction, miscarriage, death and thyroid cancer later in life.Jan 17, 2011

Pubmed Data : Endocr Pract. 2011 Jan 17:1-10. Epub 2011 Jan 17. PMID: 21247851
Article Published Date : Jan 17, 2011
Study Type : Review
Additional Links
Diseases : Birth Defects, Miscarriage, Prenatal Radiation Exposure, Radiation-Induced Illness: Radioiodine (Iodine-131), Thyroid Diseases
Problem Substances : Radioiodine 131
Adverse Pharmacological Actions : Carcinogenic, Teratogenic
[+]

The available literature indicates a linear relationship with mercury levels and IQ deficit.Nov 01, 2014

Pubmed Data : J Perinat Med. 2014 Nov ;42(6):725-9. PMID: 24698820
Article Published Date : Nov 01, 2014
Study Type : Review
Additional Links
Diseases : Birth Defects, Cognitive Decline/Dysfunction
Additional Keywords : Pregnancy, Pregnancy And Fetal Growth
Problem Substances : Mercury

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