Bone Diseases

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68 Substances Researched for Bone Diseases
NameACCKFocus
Lactoferrin323Locked
Resveratrol222Locked
Flaxseed212Locked
Vitamin B-5 (Pantothenic Acid)110Locked
Whey110Locked
Yoghurt110Locked
Boron58Locked
Vitamin C38Locked
Berberine35Locked
Curcumin25Locked
Flavonoids35Locked
Ginseng15Locked
Maqui 15Locked
Formononetin13Locked
Nicotinamide Mononucleotide13Locked
Aloe Vera12Locked
Arctigenin12Locked
Black Cohosh12Locked
Black Currant12Locked
Black Tea12Locked
Caffeic acid phenethyl ester12Locked
Calcium12Locked
Carnosic Acid12Locked
Chondroitin Sulfate12Locked
Cryptoxanthin12Locked
Deguelin12Locked
Echinacea12Locked
Fermented Foods and Beverages12Locked
Grape Seed Extract12Locked
Icariin12Locked
Isoliquiritigenin12Locked
Lignans12Locked
Ligustrazine12Locked
Melatonin12Locked
Noni12Locked
Oridonin12Locked
Palm Tree12Locked
Panax Notoginseng12Locked
Parthenolide12Locked
Prunella vulgaris12Locked
Puerarin12Locked
Rice Bran12Locked
Rooibos12Locked
Spirulina12Locked
Tocotrienols12Locked
Anthocyanins11Locked
Astragaloside11Locked
Cafestol11Locked
Cannabinoids 11Locked
Chrysanthemum Indicum11Locked
Citrus naringin11Locked
Crocin11Locked
Daisy11Locked
Ginger11Locked
Ginsenosides11Locked
Isoquercitrin11Locked
Kahweol11Locked
Mangiferin11Locked
NAC (N-acetyl-L-cysteine)11Locked
Piceatannol 11Locked
Probiotics11Locked
Psychedelics:All 11Locked
Punicalagin11Locked
Quercetin11Locked
Salvia miltiorrhiza11Locked
Tomatidine 11Locked
Vitexins11Locked
Zinc11Locked
15 Problem Substances Researched for Bone Diseases
NameACCKFocus
Sugar Sweetened Beverages120Locked
Bisphenol A 316Locked
Sodium Fluoride313Locked
Aromatase Inhibitor Drugs110Locked
Glyphosate110Locked
Letrozole (trade name Femera)110Locked
Phthalates110Locked
Proton-Pump Inhibitors110Locked
Aluminum39Locked
Electronic Cigarettes15Locked
Cadmium12Locked
Tamoxifen12Locked
Titanium Nanoparticles12Locked
Antidepressants11Locked
Fluoxetine (trade name Prozac) 11Locked
3 Therapeutic Actions Researched for Bone Diseases
NameACCKFocus
Photobiomodulation820Locked
Exercise: Resistance Training110Locked
Exercise: Aerobic12Locked
4 Problematic Actions Researched for Bone Diseases
NameACCKFocus
Electromagnetic Field Harms110Locked
Electromagnetic Radiation110Locked
Vaccination: All15Locked
Radiotherapy11Locked

View the Evidence:
104 Abstracts with Bone Diseases Research

[+]

High consumption of carbonated beverages had a moderate effect on bone mineral density.May 04, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2021 May 5 ;20(1):41. Epub 2021 May 5. PMID: 33952276
Article Published Date : May 04, 2021
Study Type : Meta Analysis, Review
Additional Links
Diseases : Bone Diseases, Fractures: Bone
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

Impact of lactoferrin on bone regenerative processes and its possible implementation in oral surgery.Aug 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Oral Health. 2020 Aug 26 ;20(1):232. Epub 2020 Aug 26. PMID: 32843024
Article Published Date : Aug 25, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : Lactoferrin
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Bone Regeneration
[+]

The findings of this study indicate that resveratrol supplementation increased some key bone biomarkers.Sep 05, 2019

Pubmed Data : Ann N Y Acad Sci. 2019 Sep 6. Epub 2019 Sep 6. PMID: 31490554
Article Published Date : Sep 05, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Resveratrol
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Association between urinary glyphosate exposure and bone mineral density in adults.Dec 07, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2023 Dec 8 ;102(49):e36506. PMID: 38065903
Article Published Date : Dec 07, 2023
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Glyphosate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Glyphosate
[+]

Effects of high intensity dynamic resistance exercise and whey protein supplements on osteosarcopenia.Aug 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Aug 5 ;12(8). Epub 2020 Aug 5. PMID: 32764397
Article Published Date : Aug 04, 2020
Study Type : Human Study
Additional Links
Substances : Whey
Diseases : Bone Diseases
Therapeutic Actions : Exercise: Resistance Training
Pharmacological Actions : Osteoprotective
[+]

Fetal exposure to bisphenols and phthalates and childhood bone mass.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Res. 2020 Jul ;186:109602. Epub 2020 May 1. PMID: 32668547
Article Published Date : Jun 30, 2020
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Bone Diseases, Fetal Origin of Adult Disease, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Fluoride exposure and prevalence of osteochondroma in drinking water Endemic fluorosis areas of Heilongjiang Province, China.Nov 02, 2023

Pubmed Data : Int J Environ Health Res. 2023 Nov 3:1-14. Epub 2023 Nov 3. PMID: 37921081
Article Published Date : Nov 02, 2023
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Fluoride Toxicity
Problem Substances : Sodium Fluoride
[+]

Greater yogurt consumption is associated with increased bone mineral density and physical function in older adults.Apr 30, 2017

Pubmed Data : Osteoporos Int. 2017 May 1. Epub 2017 May 1. PMID: 28462469
Article Published Date : Apr 30, 2017
Study Type : Human Study
Additional Links
Substances : Yoghurt
Diseases : Aging, Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Aging, Bone Diseases, Osteoprotective, Yoghurt
[+]

Long-term exposure to an electromagnetic field affects bone and thyroid metabolism and also increases oxidative stress index by increasing the total oxidant status and decreasing the antioxidant status.Jan 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2016 ;9:745-54. Epub 2016 Feb 12. PMID: 26929645
Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Hypothyroidism, Oxidative Stress
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Adverse Pharmacological Actions : Endocrine Disruptor: Thyroid, Oxidant
[+]

Long-term proton pump inhibitors use is associated with risk of bone complications.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tunis Med. 2018 Mar ;96(3):193-197. PMID: 30325487
Article Published Date : Feb 28, 2018
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Osteoporosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Peripubertal aromatase inhibition in male rats has adverse long-term effects on bone strength and growth and induces prostatic hyperplasia.Oct 01, 2010

Pubmed Data : J Endocrinol. 2010 Oct;207(1):27-34. Epub 2010 Jul 30. PMID: 20675302
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Children: Impaired Growth, Drug-Induced Toxicity , Prostatic Hyperplasia: Benign
Problem Substances : Aromatase Inhibitor Drugs, Letrozole (trade name Femera)
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

These result shows that pantothenic acid rich diet can protect bone loss from estrogen deficiency.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(8):5008-5018. Epub 2019 Aug 15. PMID: 31497217
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-5 (Pantothenic Acid)
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

This study indicates that daily consumption of 6 g/d of flaxseed oil may reduce bone resorption in hemodialysis patients.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Kidney Dis. 2018 07 ;12(4):215-222. PMID: 30087216
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Bone Diseases, Hemodialysis
Pharmacological Actions : Osteoprotective
[+]

Treatment of human cartilage defects by means of Nd:YAG laser therapy.Dec 31, 2011

Pubmed Data : J Biol Regul Homeost Agents. 2012 ;26(4):701-11. PMID: 23241120
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Bone Diseases
Therapeutic Actions : Photobiomodulation
[+]

Ascorbic acid could be a promising candidate for the prevention and healing of bone-related diseases.Dec 03, 2019

Pubmed Data : J Biol Regul Homeost Agents. 2019 Dec 4 ;33(6). Epub 2019 Dec 4. PMID: 31797649
Article Published Date : Dec 03, 2019
Study Type : Human In Vitro
Additional Links
Substances : Vitamin C
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Mesenchymal Stem Cells
[+]

E-cigarette vapour condensate reduces viability and impairs function of human osteoblasts.Aug 27, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxics. 2022 Aug 28 ;10(9). Epub 2022 Aug 28. PMID: 36136470
Article Published Date : Aug 27, 2022
Study Type : Human In Vitro
Additional Links
Diseases : Bone Diseases
Additional Keywords : Increased Risk
Problem Substances : Electronic Cigarettes
[+]

Maqui berry and ginseng extracts reduce cigarette smoke-induced cell injury.Dec 13, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Dec 14 ;11(12). Epub 2022 Dec 14. PMID: 36552669
Article Published Date : Dec 13, 2022
Study Type : Human In Vitro
Additional Links
Substances : Ginseng, Maqui
Diseases : Bone Diseases, Smoking
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

Repercussions of bisphenol A on the physiology of human osteoblasts. May 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 May 11 ;23(10). Epub 2022 May 11. PMID: 35628159
Article Published Date : May 10, 2022
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Bone Diseases
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

Transferrin enhances the osteotoxic effects of aluminum.Apr 01, 1991

Pubmed Data : Am J Physiol. 1991 Apr ;260(4 Pt 1):E537-43. PMID: 2018119
Article Published Date : Apr 01, 1991
Study Type : Human In Vitro
Additional Links
Diseases : Bone Diseases, Bone Diseases: Metabolic
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Formononetin improves the inflammatory response and bone destruction in knee joint lesions.Mar 31, 2023

Pubmed Data : Phytother Res. 2023 Apr 1. Epub 2023 Apr 1. PMID: 37002905
Article Published Date : Mar 31, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Formononetin
Diseases : Bone Diseases, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Osteoprotective
[+]

Nicotinamide mononucleotide alleviates Aluminum induced bone loss by inhibiting the TXNIP-NLRP3 inflammasome.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Appl Pharmacol. 2019 Jan 1 ;362:20-27. Epub 2018 Oct 4. PMID: 30292833
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Nicotinamide Mononucleotide
Diseases : Aluminum Toxicity , Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Osteoprotective
Problem Substances : Aluminum
[+]

Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacol Res. 2023 Jun ;192:106778. Epub 2023 Apr 23. PMID: 37094714
Article Published Date : May 31, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Vitamin C deficiency mimicking inflammatory bone disease of the hand.Jun 08, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pediatr Rheumatol Online J. 2020 Jun 9 ;18(1):45. Epub 2020 Jun 9. PMID: 32517792
Article Published Date : Jun 08, 2020
Study Type : Human: Case Report
Additional Links
Diseases : Bone Diseases, Scurvy, Vitamin C Deficiency
Additional Keywords : Risk Factors
[+]

Oral administration of melatonin contained in drinking water increased bone strength in naturally aged mice.Aug 31, 2020

Pubmed Data : Acta Histochem. 2020 Sep ;122(6):151596. Epub 2020 Jul 18. PMID: 32778234
Article Published Date : Aug 31, 2020
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Acacetin inhibits RANKL-induced osteoclastogenesis and LPS-induced bone loss by modulating NFATc1 transcription.Oct 29, 2021

Pubmed Data : Biochem Biophys Res Commun. 2021 Oct 30 ;583:146-153. Epub 2021 Oct 30. PMID: 34763194
Article Published Date : Oct 29, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Acemannan is an effective bioactive agent for bone regeneration.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent Sci. 2018 Dec ;13(4):334-341. Epub 2018 Jul 20. PMID: 30895142
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

An aqueous extract of Prunella vulgaris L. ameliorates cadmium-induced bone loss.Sep 30, 2023

Pubmed Data : Food Chem Toxicol. 2023 Oct ;180:114005. Epub 2023 Aug 26. PMID: 37640280
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Problem Substances : Cadmium
[+]

Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.Apr 14, 2016

Pubmed Data : Biochem Pharmacol. 2016 Apr 15 ;106:82-93. Epub 2016 Mar 3. PMID: 26947453
Article Published Date : Apr 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Arctigenin is a promising candidate for the treatment of osteoclast-related osteolytic diseases caused by excessive osteoclast formation.Oct 13, 2018

Pubmed Data : J Cell Biochem. 2018 Oct 14. Epub 2018 Oct 14. PMID: 30317692
Article Published Date : Oct 13, 2018
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Bone Diseases, Titanium Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Ascorbic acid induces osteoblast differentiation of human suspension mononuclear cells.Apr 30, 2014

Pubmed Data : Cytotherapy. 2014 May ;16(5):674-82. Epub 2013 Oct 29. PMID: 24176546
Article Published Date : Apr 30, 2014
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Auricular cartilage regeneration using chondroitin sulfate-based hydrogel with mesenchymal stem cells in rabbits.Sep 30, 2024

Pubmed Data : Artif Organs. 2024 Oct ;48(10):1100-1111. Epub 2024 Jul 19. PMID: 39031117
Article Published Date : Sep 30, 2024
Study Type : Animal Study
Additional Links
Substances : Chondroitin Sulfate
Diseases : Bone Diseases
Additional Keywords : Bone Regeneration, Mesenchymal Stem Cells
[+]

Berberine ameliorates nonalcoholic fatty liver disease-induced bone loss by inhibiting ferroptosis.May 06, 2024

Pubmed Data : Bone. 2024 May 7 ;185:117114. Epub 2024 May 7. PMID: 38723878
Article Published Date : May 06, 2024
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Bone Diseases, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Osteoprotective
[+]

Berberine can be a potential therapeutic agent for osteoclast-related bone diseases.Mar 03, 2019

Pubmed Data : Am J Chin Med. 2019 Mar 4:1-17. Epub 2019 Mar 4. PMID: 30827151
Article Published Date : Mar 03, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berberine
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Osteoprotective
[+]

Better measurement of bone mechanical properties were observed for boron supplementation.Dec 31, 2005

Pubmed Data : Biofactors. 2006 ;28(3-4):195-201. PMID: 17473380
Article Published Date : Dec 31, 2005
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Blackcurrant supplementation improves trabecular bone mass in young but not aged mice.Nov 04, 2018

Pubmed Data : Nutrients. 2018 Nov 5 ;10(11). Epub 2018 Nov 5. PMID: 30400569
Article Published Date : Nov 04, 2018
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Boron preserves bone mass in rats that have been exposed to intense exercise.Dec 31, 2001

Pubmed Data : J Clin Densitom. 2002 ;5(2):187-92. PMID: 12110762
Article Published Date : Dec 31, 2001
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Bone Diseases
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Osteoprotective
[+]

Caffeic acid phenethyl ester ameliorates titanium particle-induced bone loss and inflammatory reaction.Nov 11, 2023

Pubmed Data : Biochem Biophys Res Commun. 2023 Nov 12 ;681:47-54. Epub 2023 Sep 20. PMID: 37751634
Article Published Date : Nov 11, 2023
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Bone Diseases, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Calcium supplementation attenuates fluoride-induced bone injury.Mar 04, 2024

Pubmed Data : J Hazard Mater. 2024 Mar 5 ;465:133411. Epub 2024 Jan 2. PMID: 38181596
Article Published Date : Mar 04, 2024
Study Type : Animal Study
Additional Links
Substances : Calcium
Diseases : Bone Diseases, Fluoride Toxicity
Pharmacological Actions : Anti-Apoptotic, Osteogenic
Problem Substances : Sodium Fluoride
[+]

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.Sep 30, 2017

Pubmed Data : J Mol Med (Berl). 2017 Oct ;95(10):1065-1076. Epub 2017 Jul 4. PMID: 28674855
Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Osteoprotective
Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective
[+]

Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:724256. Epub 2021 Sep 29. PMID: 34658863
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Cohosh
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo.Dec 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Dec 17. Epub 2019 Dec 17. PMID: 31845532
Article Published Date : Dec 16, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Bone Diseases, Osteoarthritis
Pharmacological Actions : Osteoprotective
Problem Substances : Titanium Nanoparticles
[+]

Deguelin inhibits RANKL-induced osteoclastogenesis in vitro and prevents inflammation-mediated bone loss in vivo.Feb 28, 2019

Pubmed Data : J Cell Physiol. 2019 Mar ;234(3):2719-2729. Epub 2018 Aug 5. PMID: 30078209
Article Published Date : Feb 28, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Deguelin
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Echinacoside inhibits osteoclast function by down-regulating PI3K/Akt/C-Fos to alleviate osteolysis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:930053. Epub 2022 Jun 24. PMID: 35814196
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Effects of nutritional deficiency of boron on the bones of the appendicular skeleton of mice.Sep 03, 2018

Pubmed Data : Biol Trace Elem Res. 2018 Sep 4. Epub 2018 Sep 4. PMID: 30182352
Article Published Date : Sep 03, 2018
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Bone Diseases, Boron Deficiency
[+]

Enhancement of mesenchymal stem cell-driven bone regeneration by resveratrol-mediated SOX2 regulation.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Dis. 2019 Aug ;10(4):818-833. Epub 2019 Aug 1. PMID: 31440387
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Bone Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration, Mesenchymal Stem Cells
[+]

Fermented rice bran supplementation inhibits LPS-induced osteoclast formation and bone resorption.Jul 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Jul 5 ;15(13). Epub 2023 Jul 5. PMID: 37447370
Article Published Date : Jul 04, 2023
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Rice Bran
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fermented rooibos may have a beneficial effect on bone health.May 22, 2018

Pubmed Data : Food Funct. 2018 May 23. Epub 2018 May 23. PMID: 29790498
Article Published Date : May 22, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Grape seed proanthocyanidin extract prevents bone loss via regulation of osteoclast differentiation, apoptosis, and proliferation.Oct 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Oct 16 ;12(10). Epub 2020 Oct 16. PMID: 33081167
Article Published Date : Oct 15, 2020
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Herbacetin has potential for use as a therapeutic agent in disorders associated with bone loss.Apr 14, 2016

Pubmed Data : Eur J Pharmacol. 2016 Apr 15 ;777:17-25. Epub 2016 Feb 26. PMID: 26923730
Article Published Date : Apr 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids, Flaxseed
Diseases : Bone Diseases, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

High cholesterol-induced bone loss is attenuated by arctiin.Oct 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Oct 25 ;14(21). Epub 2022 Oct 25. PMID: 36364745
Article Published Date : Oct 24, 2022
Study Type : Animal Study
Additional Links
Substances : Lignans
Diseases : Bone Diseases, Embolism: Cholesterol, Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Osteoprotective
[+]

Icariin has a synergistic effect on the osteoinductivity of bone morphogenetic protein 2 at ectopic sites.Jan 09, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Orthop Surg. 2023 Jan 10. Epub 2023 Jan 10. PMID: 36628510
Article Published Date : Jan 09, 2023
Study Type : Animal Study
Additional Links
Substances : Icariin
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Influence of zoledronic acid and low-intensity laser on collagen fibers during the bone repair process.Dec 31, 2023

Pubmed Data : Acta Cir Bras. 2024 ;39:e393724. Epub 2024 Jul 15. PMID: 39016360
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bone Diseases
Therapeutic Actions : Photobiomodulation
[+]

Lactoferrin might be an effective therapeutic remedy for simultaneously reducing the inflammatory response and inducing bone regeneration.Apr 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tissue Eng Part A. 2020 Apr 13. Epub 2020 Apr 13. PMID: 32324097
Article Published Date : Apr 12, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lactoferrin
Diseases : Bone Diseases, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Regenerative
Additional Keywords : Bone Regeneration
[+]

Noni leaf and black tea enhance bone regeneration in estrogen-deficient rats.Dec 31, 2016

Pubmed Data : Nutrition. 2017 Jan ;33:42-51. Epub 2016 Sep 7. PMID: 27908549
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Black Tea, Noni
Diseases : Bone Diseases, Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Bone Regeneration, Ovariectomy-Induced Changes, Plant Extracts
[+]

Oridonin is a potential agent against inflammatory bone diseases.Aug 03, 2020

Pubmed Data : Acta Pharmacol Sin. 2020 Aug 4. Epub 2020 Aug 4. PMID: 32753731
Article Published Date : Aug 03, 2020
Study Type : Animal Study
Additional Links
Substances : Oridonin
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Panax notoginseng saponin promotes bone regeneration in distraction osteogenesis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:2895659. Epub 2021 Oct 21. PMID: 34721625
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Panax Notoginseng
Diseases : Bone Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration
[+]

Parthenolide has potential therapeutic value for bone destructive disorders that are associated with increased bone resorption.Jul 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMB Rep. 2014 Aug ;47(8):451-6. PMID: 24314143
Article Published Date : Jul 31, 2014
Study Type : Animal Study
Additional Links
Substances : Parthenolide
Diseases : Bone Diseases, Osteoarthrosis
Pharmacological Actions : Osteoprotective
[+]

Photobiomodulation therapy in bone repair associated with bone morphogenetic proteins and guided bone regeneration.Oct 31, 2018

Pubmed Data : Photomed Laser Surg. 2018 Nov ;36(11):581-588. PMID: 30422755
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Bone Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration
[+]

Preventive effect and mechanism of puerarin on rat models of disuse osteoporosisJan 31, 2019

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2019 Feb ;44(3):535-540. PMID: 30989919
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Spirulina enhances bone modelling in growing male rats by regulating growth-related hormones.Apr 23, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Apr 24 ;12(4). Epub 2020 Apr 24. PMID: 32344533
Article Published Date : Apr 23, 2020
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Bone Diseases, Hormones: Insufficient Levels
Pharmacological Actions : Osteogenic
[+]

Supplementation with β-cryptoxanthin would be beneficial for prophylaxis and for therapy of metabolic bone diseases associated with abnormal osteoclast activation.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2015 Sep ;129(1):72-7. Epub 2015 Aug 22. PMID: 26342276
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Cryptoxanthin
Diseases : Bone Diseases, Bone Diseases: Over-Active Osteoclasts
Additional Keywords : Supplementation
[+]

Tamoxifen impairs both longitudinal and cortical bone growth in young male rats.Aug 01, 2008

Pubmed Data : J Bone Miner Res. 2008 Aug;23(8):1267-77. PMID: 18348701
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Bone Diseases
Additional Keywords : Drug: Tamoxifen
Problem Substances : Tamoxifen
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

Tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Cell. 2018 Jun ;17(3):e12741. Epub 2018 Feb 28. PMID: 29488314
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Aging, Bone Diseases
[+]

The combination of PBM and nano-bone can aid in the repair of mandibular bone abnormalities.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Lasers Med Sci. 2024 ;15:e50. Epub 2024 Oct 8. PMID: 39450001
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bone Diseases
Therapeutic Actions : Photobiomodulation
Additional Keywords : Bone Regeneration
[+]

These results suggest that LLLT was effective in the treatment of chemically-induced osteoarthropathy.Dec 31, 2003

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : In Vivo. 2004 ;18(5):585-91. PMID: 15523898
Article Published Date : Dec 31, 2003
Study Type : Animal Study
Additional Links
Diseases : Bone Diseases
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation
[+]

Tocotrienols are more effective than d-alpha tocopherol in protecting the bone from free radical damage.Mar 31, 2005

Pubmed Data : N Engl J Med. 2005 Mar 31;352(13):1293-304. Epub 2005 Mar 7. PMID: 18598299
Article Published Date : Mar 31, 2005
Study Type : Animal Study
Additional Links
Substances : Palm Tree, Tocotrienols
Diseases : Bone Diseases
Pharmacological Actions : Antioxidants
[+]

20(R)-ginsenoside Rh2 is a selective osteoclastgenesis inhibitor without any cytotoxicity.Jun 14, 2009

Pubmed Data : Bioorg Med Chem Lett. 2009 Jun 15 ;19(12):3320-3. Epub 2009 Apr 18. PMID: 19428246
Article Published Date : Jun 14, 2009
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

A review of the role of lactoferrin in bone remodeling.Dec 31, 2022

Pubmed Data : Front Endocrinol (Lausanne). 2023 ;14:1218148. Epub 2023 Aug 23. PMID: 37680888
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Lactoferrin
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Additional Keywords : Bone Regeneration
[+]

A systematic review of the molecular impacts of photobiomodulation on bone regeneration.Apr 16, 2019

Pubmed Data : Prog Biophys Mol Biol. 2019 Apr 17. Epub 2019 Apr 17. PMID: 31002851
Article Published Date : Apr 16, 2019
Study Type : Review
Additional Links
Diseases : Bone Diseases
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration
[+]

A systematic review of the preventive and therapeutic effects of naringin against human malignancies.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:639840. Epub 2021 Mar 29. PMID: 33854437
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Citrus naringin
Diseases : Bone Diseases, Cancers: All, Inflammation, Metabolic Diseases, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemopreventive, Osteoprotective
[+]

Accelerated bone regeneration by astragaloside IV through stimulating the coupling of osteogenesis and angiogenesis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biol Sci. 2021 ;17(7):1821-1836. Epub 2021 Apr 24. PMID: 33994865
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Bone Diseases
Pharmacological Actions : Angiogenesis Inducing Agents, Osteogenic
Additional Keywords : Bone Regeneration
[+]

Berberine for bone regeneration: Therapeutic potential and molecular mechanisms.May 28, 2021

Pubmed Data : J Ethnopharmacol. 2021 May 29 ;277:114249. Epub 2021 May 29. PMID: 34058315
Article Published Date : May 28, 2021
Study Type : Review
Additional Links
Substances : Berberine
Diseases : Bone Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration
[+]

Bisphenol A induces pyroptotic cell death via ROS/NLRP3/Caspase-1 pathway in osteocytes MLO-Y4 .Dec 31, 2021

Pubmed Data : Food Chem Toxicol. 2022 Jan ;159:112772. Epub 2021 Dec 17. PMID: 34929351
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Bone Diseases
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
[+]

Boron deficiency has been correlated with low immune function and high incidence of osteoporosis.Nov 30, 2018

Pubmed Data : J Trace Elem Med Biol. 2018 Dec ;50:296-304. Epub 2018 Jul 24. PMID: 30262295
Article Published Date : Nov 30, 2018
Study Type : Review
Additional Links
Substances : Boron
Diseases : Bone Diseases, Boron Deficiency , Osteoporosis
Additional Keywords : Risk Factors
[+]

Cafestol may be a novel agent for bone diseases.Jun 30, 2015

Pubmed Data : Biofactors. 2015 Jul-Aug;41(4):222-31. Epub 2015 Jul 7. PMID: 26154488
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cafestol, Kahweol
Diseases : Bone Diseases, Osteoarthritis
Pharmacological Actions : MicroRNA modulator, NF-kappaB Inhibitor, Nrf2 activation, Osteogenic, Osteoprotective
Additional Keywords : Dose Response
[+]

Cannabinoids and bone regeneration.Jan 30, 2019

Pubmed Data : Drug Metab Rev. 2019 Jan 31:1-20. Epub 2019 Jan 31. PMID: 30702341
Article Published Date : Jan 30, 2019
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

Different effects of fluoride exposure on the three major bone cell types. Dec 31, 2019

Pubmed Data : Biol Trace Elem Res. 2020 Jan ;193(1):226-233. Epub 2019 Mar 14. PMID: 30877522
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Bone Diseases, Fluoride Toxicity
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Apoptotic
[+]

Enhancing osteoblast differentiation and bone repair.Oct 31, 2024

Pubmed Data : J Photochem Photobiol B. 2024 Nov ;260:113040. Epub 2024 Oct 2. PMID: 39388731
Article Published Date : Oct 31, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Bone Diseases
Therapeutic Actions : Photobiomodulation
Additional Keywords : Bone Regeneration
[+]

Evaluating the Role of probiotics in the prevention and management of age-related diseases.Mar 25, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Mar 26 ;23(7). Epub 2022 Mar 26. PMID: 35408987
Article Published Date : Mar 25, 2022
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Aging, Bone Diseases, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Neuroprotective Agents
[+]

Evaluation of efficacy of low-level laser therapy. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Lasers Med Sci. 2020 ;11(4):369-380. Epub 2020 Oct 3. PMID: 33425286
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Diseases : Bone Diseases, Breast Cancer, Burns, Carpal Tunnel Syndrome, Diabetic Ulcer, Hair Loss, Head and Neck Cancer, Skin Diseases, Tendon Injury, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Fluoxetine induces direct inhibitory effects on mesenchymal stem cell‑derived osteoprogenitor cells independent of serotonin concentration.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Apr ;19(4):2611-2619. Epub 2019 Feb 1. PMID: 30720108
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Bone Diseases
Additional Keywords : Increased Risk, Mesenchymal Stem Cells
Problem Substances : Antidepressants, Fluoxetine (trade name Prozac)
[+]

Harmine has bone anabolic effects and may be useful for the treatment of bone-decreasing diseases and bone regeneration.Jun 02, 2011

Pubmed Data : Biochem Biophys Res Commun. 2011 Jun 3 ;409(2):260-5. Epub 2011 May 6. PMID: 21570953
Article Published Date : Jun 02, 2011
Study Type : In Vitro Study
Additional Links
Substances : Psychedelics:All
Diseases : Bone Diseases
Pharmacological Actions : MicroRNA modulator, Osteoprotective
[+]

Hispolon inhibits RANKL induced osteoclast differentiation in vitro Feb 28, 2021

Pubmed Data : Immunol Lett. 2021 Mar ;231:35-42. Epub 2021 Jan 8. PMID: 33428992
Article Published Date : Feb 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Hyperoside suppresses osteoclasts differentiation and function through downregulating TRAF6/p38 MAPK signaling pathway.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Asian Nat Prod Res. 2022 Dec ;24(12):1157-1168. Epub 2022 Apr 18. PMID: 35435096
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

Isoquercitrin is a natural potential osteoinductive compound and might be valuable for the prevention or treatment of bone disorders.Jun 17, 2018

Pubmed Data : Connect Tissue Res. 2018 Jun 18:1-11. Epub 2018 Jun 18. PMID: 29852784
Article Published Date : Jun 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Isoquercitrin
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation.Jul 31, 2017

Pubmed Data : Mol Med Rep. 2017 Aug ;16(2):1328-1332. Epub 2017 Jun 12. PMID: 28627701
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin
Diseases : Bone Diseases, Osteoarthritis
[+]

N-acetylcysteine attenuates lipopolysaccharide-induced osteolysis by restoring bone remodelling balance. Feb 25, 2020

Pubmed Data : Inflammation. 2020 Feb 26. Epub 2020 Feb 26. PMID: 32103436
Article Published Date : Feb 25, 2020
Study Type : In Vitro Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Bone Diseases, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Nanoplastic impact on bone microenvironment: A snapshot from murine bone cells.Jan 14, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Hazard Mater. 2024 Jan 15 ;462:132717. Epub 2023 Oct 5. PMID: 37820528
Article Published Date : Jan 14, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Bone Diseases, Microplastic Toxicity
[+]

Osteogenic potential of zingerone, a phenolic compound in mouse mesenchymal stem cells.May 14, 2019

Pubmed Data : Biofactors. 2019 May 15. Epub 2019 May 15. PMID: 31091349
Article Published Date : May 14, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ginger
Diseases : Bone Diseases
Pharmacological Actions : MicroRNA modulator
Additional Keywords : Mesenchymal Stem Cells
[+]

Piceatannol attenuates RANKL-induced osteoclast differentiation and bone resorption.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : R Soc Open Sci. 2019 Jun ;6(6):190360. Epub 2019 Jun 12. PMID: 31312498
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Piceatannol
Diseases : Bone Diseases, Osteoporosis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
[+]

Pivotal role of boron supplementation on bone health: A narrative review.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trace Elem Med Biol. 2020 Dec ;62:126577. Epub 2020 Jun 6. PMID: 32540741
Article Published Date : Nov 30, 2020
Study Type : Review
Additional Links
Substances : Boron
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Punicalagin as a novel antioxidant agent for treating bone loss diseases.Aug 31, 2023

Pubmed Data : Exp Cell Res. 2023 Sep 1 ;430(1):113717. Epub 2023 Jul 8. PMID: 37429372
Article Published Date : Aug 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Punicalagin
Diseases : Bone Diseases, Osteoporosis, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Quercetin may be a potential drug for preventing abnormal human bone loss induced by LPS in bacteria-induced bone diseases.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2017 ;43(4):1547-1561. Epub 2017 Oct 16. PMID: 29035884
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
[+]

Radiotherapy may have a wide range of serious adverse effects in skeletal system.Jan 01, 1985

Pubmed Data : Crit Rev Diagn Imaging. 1985;23(3):235-67. PMID: 3891233
Article Published Date : Jan 01, 1985
Study Type : Commentary
Additional Links
Diseases : Bone Diseases, Sarcoma
Anti Therapeutic Actions : Radiotherapy
[+]

Salvia miltiorrhiza and its active ingredients demonstrate promising potential for bone diseases.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1276038. Epub 2023 Dec 5. PMID: 38116081
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Bone Diseases, Musculoskeletal Diseases, Osteoarthritis, Osteoporosis
[+]

The effects of crocin on bone and cartilage diseases.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:830331. Epub 2022 Jan 19. PMID: 35126154
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Crocin
Diseases : Arthritis, Bone Diseases, Osteoarthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The role of photobiomodulation in accelerating bone repair.Apr 30, 2024

Pubmed Data : Prog Biophys Mol Biol. 2024 May ;188:55-67. Epub 2024 Mar 16. PMID: 38493961
Article Published Date : Apr 30, 2024
Study Type : Review
Additional Links
Diseases : Bone Diseases
Therapeutic Actions : Photobiomodulation
Additional Keywords : Bone Regeneration
[+]

These results revealed that Chrysanthemum indicum extract could have a potential therapeutic role in bone-related disorders.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:176049. Epub 2014 Oct 28. PMID: 25530776
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Bone Diseases
Pharmacological Actions : Osteoprotective
[+]

This review delineates the role of aluminum in some human diseases, specifically bone and neurodegenerative diseases.Feb 01, 2013

Pubmed Data : Biomol Concepts. 2013 Feb ;4(1):77-87. PMID: 25436567
Article Published Date : Feb 01, 2013
Study Type : Review
Additional Links
Diseases : Bone Diseases, Neurodegenerative Diseases
Additional Keywords : Vaccine Research
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

This review examines the functional importance of vitamin C as it relates to the development and maintenance of bone tissues. Sep 10, 2015

Pubmed Data : J Bone Miner Res. 2015 Sep 11. Epub 2015 Sep 11. PMID: 26358868
Article Published Date : Sep 10, 2015
Study Type : Review
Additional Links
Substances : Vitamin C
Diseases : Bone Diseases, Bone Fractures, Osteoporosis
Additional Keywords : Epigenetic Modification, Gene Expression Regulation
[+]

Tomatidine suppresses osteoclastogenesis and mitigates estrogen deficiency-induced bone mass loss.Oct 03, 2018

Pubmed Data : FASEB J. 2018 Oct 4:fj201800920R. Epub 2018 Oct 4. PMID: 30285579
Article Published Date : Oct 03, 2018
Study Type : In Vitro Study
Additional Links
Substances : Tomatidine
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Tussilagone inhibits Osteoclastogenesis and Periprosthetic OsteolysisDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:385. Epub 2020 Apr 3. PMID: 32317967
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Daisy
Diseases : Bone Diseases
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Vitexin suppresses RANKL-induced osteoclastogenesis and prevents lipopolysaccharide (LPS)-induced osteolysis.Feb 20, 2019

Pubmed Data : J Cell Physiol. 2019 Feb 21. Epub 2019 Feb 21. PMID: 30793311
Article Published Date : Feb 20, 2019
Study Type : In Vitro Study
Additional Links
Substances : Vitexins
Diseases : Bone Diseases, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Zinc can exert a protective properties against bone loss by suppressing osteoclastogenesis.Oct 10, 2019

Pubmed Data : J Trace Elem Med Biol. 2019 Oct 11:126417. Epub 2019 Oct 11. PMID: 31653549
Article Published Date : Oct 10, 2019
Study Type : Review
Additional Links
Substances : Zinc
Diseases : Bone Diseases, Osteoarthritis
Pharmacological Actions : Osteoprotective

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