Brain Hypoxia

Name	AC	CK
Pomegranate	2	4
Resveratrol	2	4
Curcumin	2	3
Huperzine	2	3
Bacopa	1	2
Carnosine	1	2
Ephedra sinica (Ma Huang)	1	2
Flavonoids	1	2
Green Tea	1	2
L-arginine	1	2
P-Coumaric Acid	1	2
Paeoniflorin	1	2
Purslane	1	2
Sulforaphane	2	2
Tribulus	1	2
Astragaloside	1	1
Cordyceps sinensis	1	1
Ferulic acid	1	1
Ginsenosides	1	1
Puerarin	1	1

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DMT can increase survival and alleviate cellular stress in hypoxic environments.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Neurosci. 2016 ;10:423. Epub 2016 Sep 14. PMID: 27683542

Article Published Date : Dec 31, 2015

Study Type : Human In Vitro

Additional Links

Diseases : Brain: Oxidative Stress, Brain Hypoxia, Brain Ischemia

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Neuroprotective Agents

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An extract of Bacopa monnieri restored the memory in CoCl2-hypoxia mimetic mice.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:347978. Epub 2015 Aug 27. PMID: 26413121

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Bacopa

Diseases : Brain Hypoxia, Cognitive Decline/Dysfunction, Memory Disorders, Memory Loss

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

Additional Keywords : Gene Expression Regulation, Plant Extracts

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Curcumin intervention effectively reversed the Fas/FasL-mediated apoptosis and hypoxia-hypercapnia brain edema.May 31, 2015

Click here to read the entire abstract

Pubmed Data : Am J Med Sci. 2015 Jun ;349(6):521-5. PMID: 25867253

Article Published Date : May 31, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Brain Hypoxia, Hypercapnia

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

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Ephedrine, a compound found within Ephedra, can enhance spatiral orientation and memory abilities of hypoxic-ischemic brain injured rats. Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2007 Aug;32(16):1684-7. PMID: 18027668

Article Published Date : Aug 01, 2007

Study Type : Animal Study

Additional Links

Substances : Ephedra sinica (Ma Huang)

Diseases : Brain Hypoxia, Brain Ischemia

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Green tea polyphenols attenuate behavioral and oxidative responses to intermittent hypoxia. May 15, 2008

Click here to read the entire abstract

Pubmed Data : Am J Respir Crit Care Med. 2008 May 15;177(10):1135-41. Epub 2008 Feb 14. PMID: 18276944

Article Published Date : May 15, 2008

Study Type : Animal Study

Additional Links

Substances : Green Tea

Diseases : Brain Hypoxia, Hypoxia, Sleep Apnea: Central

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Huperzine A attenuates cognitive deficits and brain injury after hypoxia-ischemic brain damage in neonatal rats. Jan 01, 2003

Click here to read the entire abstract

Pubmed Data : Zhonghua Er Ke Za Zhi. 2003 Jan;41(1):42-5. PMID: 14761327

Article Published Date : Jan 01, 2003

Study Type : Animal Study

Additional Links

Substances : Huperzine

Diseases : Brain Hypoxia

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L-arginine and carnosine combination could effectively protect against hypoxia-induced neurotoxicity.Oct 21, 2019

Click here to read the entire abstract

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct 22. Epub 2019 Oct 22. PMID: 31641819

Article Published Date : Oct 21, 2019

Study Type : Animal Study

Additional Links

Substances : Carnosine, L-arginine

Diseases : Brain Hypoxia

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substance Synergy

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Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury.May 31, 2005

Click here to read the entire abstract

Pubmed Data : Pediatr Res. 2005 Jun ;57(6):858-64. Epub 2005 Mar 17. PMID: 15774834

Article Published Date : May 31, 2005

Study Type : Animal Study

Additional Links

Substances : Pomegranate

Diseases : Brain Hypoxia, Brain Ischemia

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Phytotherapy

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Paeoniflorin supplementation has potent protective efficiency against neonatal hypoxia/ischemia-induced brain injury.Feb 28, 2021

Click here to read the entire abstract

Pubmed Data : Korean J Physiol Pharmacol. 2021 Mar 1 ;25(2):97-109. PMID: 33602880

Article Published Date : Feb 28, 2021

Study Type : Animal Study

Additional Links

Substances : Paeoniflorin

Diseases : Brain: Oxidative Stress, Brain Hypoxia, Brain Injury: Traumatic

Pharmacological Actions : Antioxidants, Neuroprotective Agents

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Pinocembrin can act as a potential therapeutic strategy for intermittent hypoxia-induced neuroinflammation.Nov 10, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Neuroinflammation. 2020 Nov 11 ;17(1):337. Epub 2020 Nov 11. PMID: 33176803

Article Published Date : Nov 10, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Brain Hypoxia, Brain Inflammation , Sleep Apnea: Obstructive

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

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Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury.Dec 31, 2006

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Dev Neurosci. 2007 ;29(4-5):363-72. PMID: 17762204

Article Published Date : Dec 31, 2006

Study Type : Animal Study

Additional Links

Substances : Pomegranate, Resveratrol

Diseases : Brain Hypoxia, Brain Ischemia

Pharmacological Actions : Antioxidants, Apoptotic, Neuroprotective Agents

Additional Keywords : Plant Extracts

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Prophylactic effect and mechanism of p-coumaric acid against hypoxic cerebral edema in mice.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : Respir Physiol Neurobiol. 2019 02 ;260:95-104. Epub 2018 Nov 14. PMID: 30447305

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : P-Coumaric Acid

Diseases : Brain: Oxidative Stress, Brain Hypoxia, Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Prophylactic Agents

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Protective effect of resveratrol against hypoxia-induced neural oxidative stress.Jul 22, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Pers Med. 2022 Jul 23 ;12(8). Epub 2022 Jul 23. PMID: 35893296

Article Published Date : Jul 22, 2022

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Brain Hypoxia, Neurodegenerative Diseases

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Purslane (P. olecracea) attenuates hypoxia in nerve tissues. Jan 01, 2007

Click here to read the entire abstract

Pubmed Data : Asia Pac J Clin Nutr. 2007;16 Suppl 1:227-33. PMID: 17392109

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Purslane

Diseases : Brain Hypoxia, Hypoxia: Brain

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Tribulus terrestris can decrease the apoptosis induced by hypoxia and reoxygenation. Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Zhong Xi Yi Jie He Xue Bao. 2008 Jan;6(1):45-50. PMID: 18184546

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : Tribulus

Diseases : Brain Hypoxia, Hypoxia: Brain

Pharmacological Actions : Neuroprotective Agents

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A Cordyceps sinensis extract reduced the amount of hypoxia-induced inflammatory cytokines and transcription factors on par with the normoxic control.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Int J Med Mushrooms. 2015 ;17(9):829-40. PMID: 26756295

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Brain Hypoxia, Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Astragaloside IV reduces the hypoxia-induced injury in PC-12 cells.Sep 30, 2018

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2018 Oct ;106:419-425. Epub 2018 Jul 11. PMID: 29990829

Article Published Date : Sep 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Astragaloside

Diseases : Brain Hypoxia

Pharmacological Actions : MicroRNA modulator, Neuroprotective Agents

[+]

Curcumin protects against adverse changes associated with neuronal hypoxia. Jan 01, 2003

Click here to read the entire abstract

Pubmed Data : Asia Pac J Clin Nutr. 2003;12(1):50-60. PMID: 18461445

Article Published Date : Jan 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Brain Hypoxia

Pharmacological Actions : Neuroprotective Agents

[+]

Ferulic acid could reduce the oxidative stress induced by hypoxia in PC12 cells.Apr 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Basic Med Sci. 2015 May ;18(5):478-84. PMID: 26124934

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Ferulic acid

Diseases : Brain Hypoxia, Oxidative Stress

Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Superoxide Dismutase Up-regulation

[+]

Huperzine A protects against brain oxygen-glucose deprivation-induced injury. Feb 20, 2007

Click here to read the entire abstract

Pubmed Data : FEBS Lett. 2007 Feb 20;581(4):596-602. Epub 2007 Jan 18. PMID: 17257593

Article Published Date : Feb 20, 2007

Study Type : In Vitro Study

Additional Links

Substances : Huperzine

Diseases : Brain Hypoxia, Brain Inflammation , Hypoxia

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor

[+]

Puerarin attenuates hypoxia-resulted damages in neural stem cells by up-regulating microRNA-214.Nov 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2746-2753. PMID: 31282213

Article Published Date : Nov 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Puerarin

Diseases : Brain Hypoxia

Pharmacological Actions : MicroRNA modulator, Neuroprotective Agents

[+]

Sulforaphane protects astrocytes (brain cells) against oxidative stress and delayed death caused by oxygen and glucose deprivation.Apr 15, 2009

Click here to read the entire abstract

Pubmed Data : Glia. 2009 Apr 15;57(6):645-56. PMID: 18942756

Article Published Date : Apr 15, 2009

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Brain Hypoxia, Cerebral Ischemia, Hypoglycemia, Hypoxia, Oxidative Stress

Pharmacological Actions : Antioxidants, Apoptotic, Neuroprotective Agents

[+]

Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation.May 01, 2010

Click here to read the entire abstract

Pubmed Data : J Neurosci Res. 2010 May 1;88(6):1355-63. PMID: 19998483

Article Published Date : May 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Brain Damage, Brain Hypoxia, Brain Injury: Hippocampal Damage, Hypoglycemia, Hypoxia, Oxidative Stress

Pharmacological Actions : Neuroprotective Agents

[+]

The results indicate that the activation of the GABA(A) receptor is correlated with the neuroprotective mechanisms of ginsenoside Rb3.Jan 26, 2011

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2011 Jan 27 ;133(2):914-6. Epub 2010 Oct 20. PMID: 20969942

Article Published Date : Jan 26, 2011

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Brain Hypoxia

Pharmacological Actions : Neuroprotective Agents

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View the Evidence: 24 Abstracts with Brain Hypoxia Research

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DMT can increase survival and alleviate cellular stress in hypoxic environments.Dec 31, 2015

An extract of Bacopa monnieri restored the memory in CoCl2-hypoxia mimetic mice.Dec 31, 2014

Curcumin intervention effectively reversed the Fas/FasL-mediated apoptosis and hypoxia-hypercapnia brain edema.May 31, 2015

Ephedrine, a compound found within Ephedra, can enhance spatiral orientation and memory abilities of hypoxic-ischemic brain injured rats. Aug 01, 2007

Green tea polyphenols attenuate behavioral and oxidative responses to intermittent hypoxia. May 15, 2008

Huperzine A attenuates cognitive deficits and brain injury after hypoxia-ischemic brain damage in neonatal rats. Jan 01, 2003

L-arginine and carnosine combination could effectively protect against hypoxia-induced neurotoxicity.Oct 21, 2019

Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury.May 31, 2005

Paeoniflorin supplementation has potent protective efficiency against neonatal hypoxia/ischemia-induced brain injury.Feb 28, 2021

Pinocembrin can act as a potential therapeutic strategy for intermittent hypoxia-induced neuroinflammation.Nov 10, 2020

Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury.Dec 31, 2006

Prophylactic effect and mechanism of p-coumaric acid against hypoxic cerebral edema in mice.Dec 31, 2018

Protective effect of resveratrol against hypoxia-induced neural oxidative stress.Jul 22, 2022

Purslane (P. olecracea) attenuates hypoxia in nerve tissues. Jan 01, 2007

Tribulus terrestris can decrease the apoptosis induced by hypoxia and reoxygenation. Jan 01, 2008

A Cordyceps sinensis extract reduced the amount of hypoxia-induced inflammatory cytokines and transcription factors on par with the normoxic control.Dec 31, 2014

Astragaloside IV reduces the hypoxia-induced injury in PC-12 cells.Sep 30, 2018

Curcumin protects against adverse changes associated with neuronal hypoxia. Jan 01, 2003

Ferulic acid could reduce the oxidative stress induced by hypoxia in PC12 cells.Apr 30, 2015

Huperzine A protects against brain oxygen-glucose deprivation-induced injury. Feb 20, 2007

Puerarin attenuates hypoxia-resulted damages in neural stem cells by up-regulating microRNA-214.Nov 30, 2019

Sulforaphane protects astrocytes (brain cells) against oxidative stress and delayed death caused by oxygen and glucose deprivation.Apr 15, 2009

Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation.May 01, 2010

The results indicate that the activation of the GABA(A) receptor is correlated with the neuroprotective mechanisms of ginsenoside Rb3.Jan 26, 2011

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Brain Hypoxia

View the Evidence:
24 Abstracts with Brain Hypoxia Research