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Brain Inflammation
Views 5512
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246 Substances Researched for Brain Inflammation
Name
AC
CK
Focus
Curcumin
30
45
Resveratrol
14
21
Ginsenosides
12
20
Astaxanthin
8
14
Cannabidiol
10
14
Flavonoids
10
14
Apigenin
7
13
Luteolin
9
13
Thymoquinone
8
13
Alpha-Lipoic Acid
3
12
Berberine
6
12
Cannabinoids
9
12
Paeoniflorin
6
12
Polyphenols
8
12
EGCG (Epigallocatechin gallate)
8
11
Frankincense
2
11
Gastrodin
6
10
Ginkgo biloba
5
10
Hesperidin
5
10
Lycopene
6
10
Melatonin
6
10
Probiotics
1
10
Yoghurt
1
10
Ashwagandha
6
9
Genistein
5
9
Ginger
5
9
Tanshinone IIA
6
9
Vitamin C
5
9
Chrysin
5
8
Huperzine
5
8
Biochanin A
4
7
Honokiol
4
7
Astragaloside
3
6
Blueberry
4
6
DHA (Docosahexaenoic Acid)
4
6
Fisetin
4
6
Silibinin
3
6
Arctigenin
3
5
Bee Venom
3
5
Betulinic acid
3
5
Caffeine
3
5
Carnosic Acid
3
5
Fish Oil
3
5
Gotu Kola
3
5
Hemp Seed
4
5
Naringenin
3
5
Nobiletin
3
5
Omega-3 Fatty Acids
4
5
Palmitoylethanolamide
3
5
Piperine
3
5
Polyunsaturated Fatty Acids (PUFAs)
3
5
Toona sinensis
3
5
6-Shogaol
2
4
Bacopa
3
4
Baicalein
2
4
Burdock
2
4
Chamomile
2
4
Citrus Peel
2
4
Coconut Oil
2
4
Crocin
2
4
Delta-tetrahydrocannabinol (THC)
3
4
Ellagic Acid
2
4
Eriodictyol
2
4
Garlic
3
4
Gingerol
2
4
Hydrogen Water
2
4
Isoliquiritigenin
2
4
Lion's Mane (Hericium Erinaceus)
2
4
Lychee
2
4
Magnolol
2
4
Neem
2
4
Nettle
2
4
Parthenolide
2
4
Quercetin
3
4
Rosmarinic acid
2
4
Selenium
2
4
Sesamin
2
4
Sesamol
2
4
Sweet Potato: Purple
2
4
Tangeretin
2
4
Theaflavins
2
4
Ume (Japanese apricot)
2
4
Urolithin A
2
4
Walnut
2
4
Anthocyanins
2
3
Beta-Caryophyllene
2
3
Butterbur
2
3
Catechols
2
3
Ginseng (Korean)
2
3
Glycyrrhizin
2
3
Hydroxytyrosol
2
3
Maple Syrup
2
3
Mulberry
2
3
NAC (N-acetyl-L-cysteine)
2
3
Peony
2
3
Pterostilbene
2
3
Puerarin
2
3
Punicalagin
2
3
Reishi Mushroom
2
3
Spirulina
2
3
Sulforaphane
2
3
Turmerones
2
3
Vitamin D
2
3
Vitexins
2
3
Acorus calamus
1
2
Amla Fruit
1
2
Arginine
1
2
Artesunate
1
2
Asiatic Acid
2
2
Bamboo
1
2
Bee Pollen
1
2
Berries: All
1
2
Bifidobacterium Longum
1
2
Black Tea
1
2
Boron
1
2
Butyrate
1
2
Caffeic acid phenethyl ester
1
2
Carnosine
1
2
Carvacrol
1
2
Chinese Skullcap
1
2
Chokeberry
1
2
Choline
1
2
Chrysanthemum Indicum
1
2
Citrus naringin
1
2
Crocetin
1
2
Dandelion
2
2
Diosmin
1
2
Dong Quai
1
2
Dopa bean
1
2
EPA (Eicosapentaenoic Acid)
1
2
Echinacea
1
2
Endocannabinoids
1
2
Essential Fatty Acids
1
2
Fermented Foods and Beverages
1
2
Ferulic acid
1
2
Fiber
1
2
Formononetin
1
2
Fucoxanthin
2
2
Gallic Acid
1
2
Gamma-Oryzanol
1
2
Gardenia
1
2
Ginseng
1
2
Glucosamine
1
2
Grape Seed Extract
1
2
Green Coffee Bean
1
2
Guduchi
1
2
Hibiscus sabdariffa
1
2
Indole-3-Carbinol
1
2
Isothiocyanates
2
2
Kefir
1
2
Krill
1
2
Lactobacillus helveticus
1
2
Lactobacillus probiotics
1
2
Licorice
1
2
Lithium
1
2
Lupeol
1
2
Magnesium
1
2
Mangosteen
1
2
Modified Citrus Pectin
1
2
Moringa oleifera
1
2
Moxibustion
1
2
Myricetin
2
2
Oleocanthal
1
2
Oleuropein
1
2
Olive Oil
1
2
Onion
1
2
P-Coumaric Acid
1
2
Paeonol
2
2
Pantothenic Acid (Vitamin B-5)
1
2
Paprika
1
2
Patchouli
1
2
Phloretin
1
2
Phyllanthus amarus
1
2
Pomegranate
2
2
Propolis: Bee
1
2
Propolis: Brazillian
1
2
Purslane
1
2
Riboflavin (Vitamin B-2)
1
2
Rice Bran
2
2
Rose
1
2
Rosemary
1
2
Rutin
1
2
St. Johns Wort
1
2
Tannic Acid
1
2
Tart Cherry
1
2
Tetrahydrocurcumin
1
2
Theanine
1
2
Thiamine (B-1)
1
2
Thymol
1
2
Tualang Honey
1
2
Turmeric
2
2
Vitamin B-12
1
2
Vitamin B-3 (Niacin)
1
2
Vitamin B-6
1
2
Zerumbone
1
2
Acacia catechu
1
1
Achillea fragrantissima
1
1
Agrimony
1
1
Apple
1
1
Arugula
1
1
Ayahuasca
1
1
Babchi
1
1
Benzyl isothiocyanate
1
1
Bergamot
1
1
Black Currant
1
1
Blackberry
1
1
Cannabigerol
1
1
Cannabinoids: Synthetic
1
1
Cannabis
1
1
Carnosol
1
1
Chaga Mushroom (Inonotus obliquus)
1
1
Chia
1
1
Cordyceps sinensis
1
1
Cysteine (see N-Acetylcysteine)
1
1
Diosgenin
1
1
Elderberry
1
1
Emodin
1
1
Fucoidan
1
1
Garlic: Aged
1
1
Goji
1
1
Gold (nanoparticles)
1
1
Green Tea
1
1
Gynostemma
1
1
Hawthorn
1
1
Hemp Protein
1
1
Hibiscus
1
1
Knema laurina
1
1
Mangiferin
1
1
Matairesinol
1
1
Oleanolic acid
1
1
Olive leaf extract
1
1
Persimmon
1
1
Prickly Pear Cactus
1
1
Pycnogenol (Pine Bark)
1
1
Red Wine Extract
1
1
Safflower
1
1
Sembung Leaf
1
1
Spermidine
1
1
Strawberry
1
1
Vanillin
1
1
Vitamin E
1
1
Wasabi
1
1
Watercress
1
1
Wine
1
1
Wogonin
1
1
Xanthohumol
1
1
30 Problem Substances Researched for Brain Inflammation
Name
AC
CK
Focus
Aluminum
14
28
Mercury
3
16
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
2
12
Butyrophilin
1
10
Chlamydia Pneumoniae
1
10
Cow Milk
1
10
Streptococcal M Protein
1
10
Bisphenol A
3
5
Acrylamide
2
4
Morphine
2
4
Sodium Fluoride
2
4
Cadmium
2
3
Lead
2
3
Aluminum Chloride
1
2
Aspartame
1
2
Chlorpyrifos
1
2
Dexamethasone
1
2
Energy Drinks
1
2
Fluoride
1
2
Fluoxetine (trade name Prozac)
1
2
Glyphosate formulations
1
2
High Fructose Corn Syrup
1
2
Nanoparticles
1
2
Paraquat
1
2
Roundup (herbicide)
1
2
Simvastatin
1
2
Streptozotocin
1
2
Sugar Sweetened Beverages
1
2
Thimerosal
1
2
Amphetamine
1
1
12 Therapeutic Actions Researched for Brain Inflammation
Name
AC
CK
Focus
Exercise
10
32
Dietary Modification: Low Carbohydrate/Ketogenic
1
10
Electroacupuncture
5
10
Hyperbaric Treatment
3
6
Laser Treatment: Low-Level
3
6
Acupuncture
1
2
Cryotherapy
1
2
Dietary Modification: Low Calorie Diet
1
2
Exercise: Aerobic
1
2
Exercise: Endurance
1
2
Exercise: Swimming
1
2
Light-Emitting Diodes (LEDs) Therapy
1
1
14 Problematic Actions Researched for Brain Inflammation
Name
AC
CK
Focus
Vaccination: All
10
43
Vaccination: Mumps-Measles-Rubella (MMR)
2
13
Vaccination: Hexavalent
1
10
Vaccination: Measles
1
10
Vaccination: Adult Rubella
1
3
Vaccination: Hepatitis B
1
3
Vaccination: Mumps
1
3
Electromagnetic Field Harms
1
2
Electromagnetic Radiation
1
2
Electromagnetic Radiation: 1.8 GHz
1
2
Microwave Radiation
1
2
Nanotechnology
1
2
Vaccination: HPV (Gardasil)
1
2
Vaccination: Yellow Fever
1
1
Research Articles
567
Cumulative Knowledge Score
917
Overall Research Rating
EXCELLENT
View the Evidence:
808 Abstracts with Brain Inflammation Research
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[+]
Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation.
Mar 09, 2022
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2022 Mar 10. Epub 2022 Mar 10. PMID:
35267136
Article Published Date
: Mar 09, 2022
Study Type
: Human In Vitro, Human Study
Additional Links
Substances
:
Nobiletin
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Neuroprotective Agents
[+]
11.8% of 110 sudden infant death cases examined in the study occurred in temporal association with hexavalent vaccines.
Mar 01, 2014
Click here to read the entire abstract
Pubmed Data
: Curr Med Chem. 2014 Mar ;21(7):941-6. PMID:
24083600
Article Published Date
: Mar 01, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
Encephalitis
,
Vaccine-induced Toxicity
Anti Therapeutic Actions
:
Vaccination: All
,
Vaccination: Hexavalent
[+]
Ambient fine particulate exposure and subcortical gray matter microarchitecture in 9- and 10-year-old children across the United States.
Mar 16, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: iScience. 2023 Mar 17 ;26(3):106087. Epub 2023 Jan 31. PMID:
36915692
Article Published Date
: Mar 16, 2023
Study Type
: Human Study
Additional Links
Diseases
:
Air Pollution Linked Toxicity
,
Brain Inflammation
,
Neurodegenerative Diseases
[+]
Boswellic acids could be used to reduce peritumoral edema associated with primary and secondary brain tumors.
Dec 14, 2011
Click here to read the entire abstract
Pubmed Data
: J Pharm Biomed Anal. 2011 Dec 15 ;56(5):998-1005. Epub 2011 Jul 29. PMID:
21855244
Article Published Date
: Dec 14, 2011
Study Type
: Human Study
Additional Links
Substances
:
Frankincense
Diseases
:
Brain Edema
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
Crocin alleviates cognitive impairment associated with atherosclerosis.
Jan 26, 2022
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2022 Jan 27. Epub 2022 Jan 27. PMID:
35084779
Article Published Date
: Jan 26, 2022
Study Type
: Human Study
Additional Links
Substances
:
Crocin
Diseases
:
Atherosclerosis
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Despite a "decrease" in measles and mumps encephalitis, hospital admissions for encephalitis of "unknown etiology" have increased substantially.
Jan 01, 2017
Click here to read the entire abstract
Pubmed Data
: Lancet Infect Dis. 2017 04 ;17(4):422-430. Epub 2017 Mar 2. PMID:
28259562
Article Published Date
: Jan 01, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
Encephalitis
Anti Therapeutic Actions
:
Vaccination: All
[+]
Extracellular vesicles are increased in the serum of children with autism spectrum disorder
Aug 26, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2018 Aug 27 ;15(1):239. Epub 2018 Aug 27. PMID:
30149804
Article Published Date
: Aug 26, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Brain Inflammation
Additional Keywords
:
Exosomes
[+]
Inflammation may influence glutamate metabolism to alter behaviour, leading to depressive symptoms.
Nov 09, 2016
Click here to read the entire abstract
Pubmed Data
: Curr Top Behav Neurosci. 2016 Nov 10. Epub 2016 Aug 10. PMID:
27830574
Article Published Date
: Nov 09, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
Depressive Disorder
,
Inflammation
Additional Keywords
:
Risk Factors
[+]
Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents.
Mar 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Adv. 2021 Apr ;7(15). Epub 2021 Apr 9. PMID:
33837086
Article Published Date
: Mar 31, 2021
Study Type
: Animal Study, Human Study
Additional Links
Diseases
:
Alcohol Withdrawal
,
Brain Inflammation
Therapeutic Actions
:
Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Risk Reduction
[+]
Lipoic acid down-regulates inflammation in multiple sclerosis patients.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(9). Epub 2010 Sep 28. PMID:
20927401
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
cAMP up-regulation
,
Interleukin-17 downregulation
,
Interleukin-6 Downregulation
[+]
Low-grade inflammation is associated with apathy indirectly via deep white matter lesions in community-dwelling older adults.
Apr 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Apr 17 ;20(8). Epub 2019 Apr 17. PMID:
30999680
Article Published Date
: Apr 16, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
Inflammation
Additional Keywords
:
Risk Factors
[+]
Mild cognitive impairment patients have higher regulatory T-cell proportions compared with Alzheimer's disease-related dementia patients.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2020 ;12:624304. Epub 2021 Jan 22. PMID:
33551792
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Dementia
[+]
Milk and bacterial proteins may produce neuron-specific antigens in children with autism.
Aug 01, 2002
Click here to read the entire abstract
Pubmed Data
: J Neuroimmunol. 2002 Aug;129(1-2):168-77. PMID:
12161033
Article Published Date
: Aug 01, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Autoimmune Diseases
,
Brain Inflammation
Additional Keywords
:
Molecular Mimicry
Problem Substances
:
Butyrophilin
,
Chlamydia Pneumoniae
,
Cow Milk
,
Streptococcal M Protein
Adverse Pharmacological Actions
:
Immunoreactive
,
Immunotoxic
,
Neurotoxic
[+]
Multi-strain probiotic supplementation seems to exert a positive effect on neuroinflammation and neurocognitive impairment in HIV-1 infected subjects.
Nov 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Nov 21 ;9(11). Epub 2017 Nov 21. PMID:
29160817
Article Published Date
: Nov 20, 2017
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
HIV Infections
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Neuroglial activation and neuroinflammation in the brain of patients with autism.
Dec 31, 2004
Click here to read the entire abstract
Pubmed Data
: Ann Neurol. 2005 Jan ;57(1):67-81. PMID:
15546155
Article Published Date
: Dec 31, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Brain Inflammation
[+]
Oligopin supplementation in traumatic brain injury patients in ICU reduced inflammation and improved the clinical status.
Aug 31, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Sep ;35(9):5178-5188. Epub 2021 Aug 12. PMID:
34382717
Article Published Date
: Aug 31, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Plant Extracts
[+]
Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias.
Dec 15, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neurol Neurosurg Psychiatry. 2017 Dec 16. Epub 2017 Dec 16. PMID:
29248892
Article Published Date
: Dec 15, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Dementia: Lewy Body
Additional Keywords
:
Alzheimer's disease
,
Brain Inflammation
,
Dementia: Lewy Body
[+]
Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.
Jan 02, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2017 01 3 ;14(1):1. Epub 2017 Jan 3. PMID:
28086917
Article Published Date
: Jan 02, 2017
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.
Oct 19, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2015 Oct 20 ;85(16):1383-91. Epub 2015 Sep 11. PMID:
26362286
Article Published Date
: Oct 19, 2015
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
The combined effects of yogurt and exercise in healthy adults: Implications for biomarkers of depression and cardiovascular diseases.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Sci Nutr. 2018 Oct ;6(7):1968-1974. Epub 2018 Sep 7. PMID:
30349687
Article Published Date
: Sep 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Yoghurt
Diseases
:
Brain Inflammation
,
C-Reactive Protein
,
Cardiovascular Diseases
,
Depression
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
The flavonoid rich black currant ethanolic gemmotherapy extract elicits neuroprotective effects.
Apr 18, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2023 Apr 19 ;28(8). Epub 2023 Apr 19. PMID:
37110805
Article Published Date
: Apr 18, 2023
Study Type
: Human Study
Additional Links
Substances
:
Black Currant
,
Flavonoids
Diseases
:
Alcohol Toxicity
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
The levels of blood mercury and inflammatory-related neuropeptides in the serum are correlated in children with autism spectrum disorder.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2016 Jun ;31(3):593-9. Epub 2016 Jan 6. PMID:
26738726
Article Published Date
: May 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Autism
,
Brain Inflammation
Problem Substances
:
Mercury
[+]
The measles vaccine can induce encephalitis.
Jan 19, 2017
Click here to read the entire abstract
Pubmed Data
: Vaccine. 2017 12 19 ;35(52):7309-7311. Epub 2017 Nov 8. PMID:
29128384
Article Published Date
: Jan 19, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
Encephalitis
,
Vaccine-induced Toxicity
Anti Therapeutic Actions
:
Vaccination: All
,
Vaccination: Measles
,
Vaccination: Mumps-Measles-Rubella (MMR)
[+]
The results suggest that aluminum-induced CRP may in part contribute to a pathophysiological state associated with a chronic systemic inflammation of the human vasculature.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Inorg Biochem. 2015 Aug 1. Epub 2015 Aug 1. PMID:
26265215
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
C-Reactive Protein
,
Inflammation
Additional Keywords
:
Increased Risk
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These findings suggest that predisposition to autoimmunity, and immune/inflammatory activation, may be associated with autistic regression.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Dev Med Child Neurol. 2017 09 ;59(9):947-951. Epub 2017 Apr 6. PMID:
28383115
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Autoimmune Diseases
,
Brain Inflammation
[+]
This is the first study demonstrating inflammation within the neurocircuitry of OCD.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: JAMA Psychiatry. 2017 Aug 1 ;74(8):833-840. PMID:
28636705
Article Published Date
: Jul 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
Obsessive-Compulsive Disorder
[+]
Women engaging in greater amounts of exercising showed lower TNF-α levels and greater dorsolateral prefrontal cortex and temporal lobe volumes.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2021 ;13:615247. Epub 2021 Mar 8. PMID:
33776741
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Mercury stimulates VEGF and IL-6 release from human mast cells which could disrupt the blood-brain-barrier and permit brain inflammation.
Mar 11, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2010 Mar 11 ;7:20. Epub 2010 Mar 11. PMID:
20222982
Article Published Date
: Mar 11, 2010
Study Type
: Human In Vitro
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
,
Brain Inflammation
Additional Keywords
:
Blood Brain Barrier
,
Heavy Metals and Autism
,
Vaccine Research
Problem Substances
:
Mercury
Adverse Pharmacological Actions
:
Blood Brain Barrier Injury
,
Inflammatory
,
Interleukin-6 up-regulation
,
Vascular Endothelial Growth Factor C Up-Regulation
[+]
This demonstrates the broad neuroprotective action of apigenin against AD pathogenesis in a human disease model.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:31450. Epub 2016 Aug 12. PMID:
27514990
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
A case report of fatal encephalitis asssociated with the measles rubella vaccine.
Dec 01, 2013
Click here to read the entire abstract
Pubmed Data
: J Clin Virol. 2013 Dec ;58(4):737-40. Epub 2013 Oct 24. PMID:
24216323
Article Published Date
: Dec 01, 2013
Study Type
: Human: Case Report
Additional Links
Diseases
:
Brain Inflammation
,
Encephalitis
Anti Therapeutic Actions
:
Vaccination: Adult Rubella
,
Vaccination: All
,
Vaccination: Mumps-Measles-Rubella (MMR)
[+]
A case series of multiple sclerosis-like persistent inflammatory activity and encephalitis in the brain of hepatitis B vaccinees.
Jul 22, 1999
Click here to read the entire abstract
Pubmed Data
: Neurology. 1999 Jul 22 ;53(2):396-401. PMID:
10430433
Article Published Date
: Jul 22, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Brain Inflammation
,
Multiple Sclerosis
Anti Therapeutic Actions
:
Vaccination: All
,
Vaccination: Hepatitis B
[+]
Astragaloside IV attenuates neuroinflammation and ameliorates cognitive impairment in Alzheimer's disease.
Jan 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2023 Feb ;9(2):e13411. Epub 2023 Feb 3. PMID:
36820018
Article Published Date
: Jan 31, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Brain-targeting emodin mitigates ischemic stroke.
Jun 27, 2023
Click here to read the entire abstract
Pubmed Data
: Transl Stroke Res. 2023 Jun 28. Epub 2023 Jun 28. PMID:
37380800
Article Published Date
: Jun 27, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Emodin
Diseases
:
Brain Inflammation
,
Stroke: Ischemic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Encephalitis with seizures in 5 patients with confirmed mumps vaccine strain in cerebrospinal fluid.
Feb 15, 2015
Click here to read the entire abstract
Pubmed Data
: J Neurol Sci. 2015 Feb 15 ;349(1-2):226-8. Epub 2014 Dec 18. PMID:
25542078
Article Published Date
: Feb 15, 2015
Study Type
: Human: Case Report
Additional Links
Diseases
:
Brain Inflammation
,
Encephalitis
Anti Therapeutic Actions
:
Vaccination: All
,
Vaccination: Mumps
[+]
Erinacine A prevents lipopolysaccharide-mediated glial cell activation to protect dopaminergic neurons against inflammatory factor-induced cell death.
Jan 11, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2022 Jan 12 ;23(2). Epub 2022 Jan 12. PMID:
35054997
Article Published Date
: Jan 11, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Mapping molecular networks within Clitoria ternatea against LPS-induced neuroinflammation.
Apr 11, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceuticals (Basel). 2022 Apr 12 ;15(4). Epub 2022 Apr 12. PMID:
35455463
Article Published Date
: Apr 11, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Butterfly Pea
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
[+]
Multi-target effects of ß-caryophyllene and carnosic acid at the crossroads of mitochondrial dysfunction and neurodegeneration.
Jun 17, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2022 Jun 18 ;11(6). Epub 2022 Jun 18. PMID:
35740096
Article Published Date
: Jun 17, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Beta-Caryophyllene
,
Carnosic Acid
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Palmitoylethanolamide ameliorates neuroinflammation.
Jun 10, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurosci Lett. 2022 Jun 11 ;781:136648. Epub 2022 Apr 22. PMID:
35469820
Article Published Date
: Jun 10, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Palmitoylethanolamide
Diseases
:
Brain Inflammation
,
Intracerebral Hemorrhage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Sargassum horneri extract regulates neuroinflammation.
Nov 02, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Issues Mol Biol. 2022 Nov 3 ;44(11):5416-5426. Epub 2022 Nov 3. PMID:
36354679
Article Published Date
: Nov 02, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Seaweed: Brown
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Nov ;107:1523-1529. Epub 2018 Sep 5. PMID:
30257370
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries.
Jul 14, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Jul 15:173294. Epub 2020 Jul 15. PMID:
32681941
Article Published Date
: Jul 14, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Brain Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
6-Gingerol, an active constituent of ginger, attenuates lipopolysaccharide-induced oxidation, inflammation, cognitive deficits.
Mar 31, 2021
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2021 Apr ;45(4):e13660. Epub 2021 Feb 24. PMID:
33624846
Article Published Date
: Mar 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
6-Shogaol exerts neuroprotective effects on dopaminergic neurons in vitro and in vivo parkinson's disease models.
Aug 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Pharmacol Sin. 2013 Sep ;34(9):1131-9. Epub 2013 Jul 1. PMID:
23811724
Article Published Date
: Aug 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
6-shogaol may play a role in inhibiting glial cell activation and reducing memory impairment in animal models of dementia.
Jun 19, 2014
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2014 Jun 20 ;449(1):8-13. Epub 2014 May 2. PMID:
24796668
Article Published Date
: Jun 19, 2014
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Brain Inflammation
,
Dementia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
A cecal slurry mouse model of sepsis leads to acute consumption of vitamin C in the brain.
Mar 25, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Mar 26 ;12(4). Epub 2020 Mar 26. PMID:
32224930
Article Published Date
: Mar 25, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Brain Inflammation
,
Sepsis
,
Vitamin C Deficiency
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Risk Factors
[+]
A combination of ginger and peony root may prevent memory impairment in AD by inhibiting Aβ accumulation and inflammation in the brain.
Nov 29, 2015
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2015 Nov 30. Epub 2015 Nov 30. PMID:
26639976
Article Published Date
: Nov 29, 2015
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ginger
,
Peony
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
[+]
A combination of resveratrol and curcumin is effective against aluminum chloride-induced neuroinflammation in rats.
Feb 06, 2017
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2017 Feb 7. Epub 2017 Feb 7. PMID:
28222524
Article Published Date
: Feb 06, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Resveratrol
Diseases
:
Aluminum Toxicity
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Natural Substance Synergy
Problem Substances
:
Aluminum Chloride
[+]
A Spirulina diet given to lactating mothers can protect against neuroinflammation and decreased antioxidant defence in brain of suckling pups.
Aug 28, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2016 Aug 29:1-11. Epub 2016 Aug 29. PMID:
27571388
Article Published Date
: Aug 28, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Spirulina
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
A. calamus prevented from memory deficits and stress through controlling oxidative stress and inflammation processes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Prev Med. 2018 ;9:85. Epub 2018 Oct 12. PMID:
30450168
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Acorus calamus
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-κB signaling pathway.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Brain Behav Immun. 2019 07 ;79:228-235. Epub 2019 Feb 7. PMID:
30738841
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chrysin
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Absence of gut microbiota affects lipid metabolism in the prefrontal cortex of mice.
Oct 06, 2019
Click here to read the entire abstract
Pubmed Data
: Neurol Res. 2019 Oct 7:1-9. Epub 2019 Oct 7. PMID:
31587617
Article Published Date
: Oct 06, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Dysbiosis
Additional Keywords
:
Gut-brain Axis
[+]
Acacetin alleviates neuroinflammation and oxidative stress injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Transl Neurosci. 2022 Jan 1 ;13(1):483-494. Epub 2022 Dec 21. PMID:
36590896
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acacetin attenuates neuroinflammation.
Jun 30, 2012
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2012 Jul ;37(7):1560-7. Epub 2012 Mar 24. PMID:
22447574
Article Published Date
: Jun 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
,
Postaglandin PGE2 downregulation
[+]
Acupuncture is an effective treatment for chronic overlapping pain conditions and provide insight into treatment response variability.
Jul 03, 2018
Click here to read the entire abstract
Pubmed Data
: J Pain. 2018 Jul 4. Epub 2018 Jul 4. PMID:
29981376
Article Published Date
: Jul 03, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Chronic Pain
Therapeutic Actions
:
Acupuncture
Pharmacological Actions
:
Analgesics
[+]
Acute exposure to 900-MHz microwaves induces glial reactivity and biochemical modifications in the rat brain.
Dec 01, 2004
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2004 Dec ;17(3):445-54. PMID:
15571980
Article Published Date
: Dec 01, 2004
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Acute neuroinflammation promotes cell responses to 1800 MHz GSM electromagnetic fields in the rat cerebral cortex.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2017 Oct ;32(3):444-459. Epub 2017 Jun 3. PMID:
28578480
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
Anti Therapeutic Actions
:
Electromagnetic Radiation: 1.8 GHz
[+]
Addition of tart cherry to the diet may promote healthy aging or delay the onset of neurodegenerative diseases.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Age (Dordr). 2016 Dec ;38(5-6):393-404. Epub 2016 Aug 30. PMID:
27578256
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Tart Cherry
Diseases
:
Aging
,
Brain Inflammation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Administering crocin ameliorates anxiety-like behaviors and reduces the inflammatory response in amyloid-beta induced neurotoxicity.
Mar 07, 2021
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2021 Mar 8. Epub 2021 Mar 8. PMID:
33686675
Article Published Date
: Mar 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Anxiety
,
Brain Inflammation
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Administering curcumin may alleviate cerebral inflammation resulting from intracerebral hemorrhage.
Mar 25, 2016
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2016 Mar 26 ;620:74-82. Epub 2016 Mar 26. PMID:
27026486
Article Published Date
: Mar 25, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Inflammation
,
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-17 downregulation
[+]
Administration of synthetic 2-AG to mice after CHI led to significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls.
Oct 03, 2001
Click here to read the entire abstract
Pubmed Data
: Nature. 2001 Oct 4 ;413(6855):527-31. PMID:
11586361
Article Published Date
: Oct 03, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
,
Endocannabinoids
Diseases
:
Brain Edema
,
Brain Inflammation
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Significant Treatment Outcome
[+]
Aerobic exercise significantly increases the chronic unpredictable mild stress-depressed mice hippocampus expression of miR-223.
Apr 13, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2020 Apr 14 ;17(8). Epub 2020 Apr 14. PMID:
32295141
Article Published Date
: Apr 13, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Depression
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Aerobic training and royal jelly improved inflammatory and regulatory factors of autoimmunity and reduced anxiety and depression.
Jan 19, 2023
Click here to read the entire abstract
Pubmed Data
: Mult Scler Relat Disord. 2023 Jan 20 ;70:104527. Epub 2023 Jan 20. PMID:
36696832
Article Published Date
: Jan 19, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Royal Jelly
Diseases
:
Brain Inflammation
,
Multiple Sclerosis
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-10 upregulation
,
Interleukin-17 downregulation
,
Interleukin-23 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Aloin attenuates cognitive impairment and inflammation induced by d-galactose via down-regulating ERK, p38 and NF-κB signaling pathway.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Jul ;72:48-54. Epub 2019 Apr 5. PMID:
30959371
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha-lipoic acid improved motor function in MPTP-induced Parkinsonian mice by reducing neuroinflammation in the nigral and spinal cord.
Apr 28, 2022
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2022 Apr 29 ;781:136669. Epub 2022 Apr 29. PMID:
35490905
Article Published Date
: Apr 28, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha-mangostin reduces the overactivation of the ERK signaling and also restored autism-like behavioral and neurochemical alterations.
Feb 24, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Sci. 2021 Feb 25 ;11(3). Epub 2021 Feb 25. PMID:
33669120
Article Published Date
: Feb 24, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Mangosteen
Diseases
:
Autism
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Aluminium, fluoride and a combination of aluminium-fluoride treatments caused an increase in brain lipid peroxidation products and reactive oxygen species formation.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Pathophysiology. 2015 Mar ;22(1):39-48. Epub 2014 Dec 13. PMID:
25577494
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Brain Inflammation
,
Fluoride Toxicity
,
Neurodegenerative Diseases
,
Oxidative Stress
Additional Keywords
:
Increased Risk
,
Synergistic Toxicity
Problem Substances
:
Aluminum
,
Fluoride
,
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminum can induce neuroinflammation and could lead to learning and memory deficits.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Chemosphere. 2016 May ;151:289-95. Epub 2016 Mar 15. PMID:
26946116
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
Additional Keywords
:
aluminum
,
aluminum toxicity
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Inflammatory
[+]
Amelioration of intracerebroventricular streptozotocin-induced cognitive dysfunction by Ocimum sanctum.
Sep 30, 2022
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2022 Oct ;37(7):2533-2543. Epub 2022 Jul 28. PMID:
35900690
Article Published Date
: Sep 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Holy Basil
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Diabetes: Cognitive Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Amelioration of oxidative stress, cholinergic dysfunction, and neuroinflammation in scopolamine-induced amnesic rats fed with pomegranate seed.
Mar 27, 2022
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2022 Mar 28. Epub 2022 Mar 28. PMID:
35348947
Article Published Date
: Mar 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Andrographolide ameliorates neuroinflammation in APP/PS1 transgenic mice .
Jun 30, 2021
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2021 Jul ;96:107808. Epub 2021 May 30. PMID:
34162168
Article Published Date
: Jun 30, 2021
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Andrographolide
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.
Nov 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Nov 28 ;18(12). Epub 2017 Nov 28. PMID:
29182579
Article Published Date
: Nov 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
[+]
Anti-inflammatory and anti-oxidant activity of Hidroxin in rotenone-induced Parkinson's disease.
Sep 02, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2020 Sep 3 ;9(9). Epub 2020 Sep 3. PMID:
32899274
Article Published Date
: Sep 02, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Anti-neuroinflammatory effect of alantolactone through the suppression of the NF-κB and MAPK signaling pathways.
Jan 17, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cells. 2019 07 18 ;8(7). Epub 2019 Jul 18. PMID:
31323885
Article Published Date
: Jan 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Elecampane
Diseases
:
Brain Inflammation
,
Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Anti-neuroinflammatory effects of a food-grade phenolic-enriched maple syrup extract in a mouse model of Alzheimer's disease.
Oct 03, 2019
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2019 Oct 4:1-10. Epub 2019 Oct 4. PMID:
31583972
Article Published Date
: Oct 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Maple Syrup
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
[+]
Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone.
Oct 11, 2019
Click here to read the entire abstract
Pubmed Data
: Physiol Behav. 2019 Oct 12 ;212:112699. Epub 2019 Oct 12. PMID:
31614158
Article Published Date
: Oct 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
[+]
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
Jan 07, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lipids Health Dis. 2020 Jan 8 ;19(1):4. Epub 2020 Jan 8. PMID:
31915015
Article Published Date
: Jan 07, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-10 downregulation
[+]
Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice.
Apr 26, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2018 Apr 27. Epub 2018 Apr 27. PMID:
29704081
Article Published Date
: Apr 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Nettle
Diseases
:
Anxiety
,
Brain Inflammation
,
Depression
,
Diabetic Complications
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antidepressant and anxiolytic-like effects of ayahuasca in rats subjected to LPS-induced neuroinflammation.
Jul 13, 2022
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2022 Jul 14 ;434:114007. Epub 2022 Jul 14. PMID:
35843462
Article Published Date
: Jul 13, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ayahuasca
Diseases
:
Brain Inflammation
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Antidepressant-like mechanism of honokiol in a rodent model of corticosterone-induced depression.
Sep 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Integr Neurosci. 2020 Sep 30 ;19(3):459-467. PMID:
33070525
Article Published Date
: Sep 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
[+]
Antidepressive effect of arctiin by attenuating neuroinflammation.
Jan 04, 2020
Click here to read the entire abstract
Pubmed Data
: ACS Chem Neurosci. 2020 08 5 ;11(15):2214-2230. Epub 2020 Jul 15. PMID:
32609480
Article Published Date
: Jan 04, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Burdock
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin restored immune function and decreased neuroinflammation in an experimental autoimmune encephalomyelitis model.
Jun 03, 2015
Click here to read the entire abstract
Pubmed Data
: J Neuroimmune Pharmacol. 2015 Jun 4. Epub 2015 Jun 4. PMID:
26040501
Article Published Date
: Jun 03, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Autoimmune Diseases
,
Brain Inflammation
,
Encephalomyelitis
,
Multiple Sclerosis: Relapsing-Remitting
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Gene Expression
[+]
Apple polyphenols extract alleviated dextran sulfate sodium induced acute ulcerative colitis.
Nov 04, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2021 Nov 5 ;10(11). Epub 2021 Nov 5. PMID:
34828992
Article Published Date
: Nov 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
Diseases
:
Brain Inflammation
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Arctigenin may have anti-inflammatory and immunosuppressive properties via inhibiting Th17 cells.
Oct 05, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2015 Oct 6. Epub 2015 Oct 6. PMID:
26440666
Article Published Date
: Oct 05, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
,
Burdock
Diseases
:
Autoimmune Diseases
,
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Immunomodulatory: Th17 downregulation
,
Immunosuppressive Agents
[+]
Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation.
Sep 09, 2020
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2020 Sep 10. Epub 2020 Sep 10. PMID:
32964428
Article Published Date
: Sep 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Artesunate may exert protective effects against cerebral ischemia/reperfusion injury.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 May ;17(5):6639-6646. Epub 2018 Mar 1. PMID:
29512760
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Brain Inflammation
,
Cerebral Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Ashwagandha may serve as an effective dietary supplement for management of sleep deprivation induced stress and associated functional impairments.
Dec 20, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2016 Dec 21. Epub 2016 Dec 21. PMID:
28004351
Article Published Date
: Dec 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ashwagandha
Diseases
:
Brain Inflammation
,
Insomnia
,
Sleep Disorders
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Ashwagandha treatment reversed the cytoplasmic mislocalization of hTDP-43 in spinal motor neurons and in brain.
Dec 06, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurotherapeutics. 2016 Dec 7. Epub 2016 Dec 7. PMID:
27928708
Article Published Date
: Dec 06, 2016
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ashwagandha
Diseases
:
Amyotrophic lateral sclerosis (ALS)
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction.
Feb 17, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2019 Feb 18 ;17(2). Epub 2019 Feb 18. PMID:
30781690
Article Published Date
: Feb 17, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury.
Sep 18, 2018
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2018 Sep 19. Epub 2018 Sep 19. PMID:
30243665
Article Published Date
: Sep 18, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
,
Spinal Cord Inflammation
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin attenuates neuroinflammation in status epilepticus.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2020 ;14:1651-1662. Epub 2020 Apr 30. PMID:
32431490
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
,
Epilepsy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Astaxanthin exerts different anti-inflammatory effects in female and male brains.
Jan 29, 2016
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2016 Jan 30 ;96(2):615-8. Epub 2015 Feb 25. PMID:
25678261
Article Published Date
: Jan 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Aging
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
[+]
Astaxanthin had an anti-depressant effect on diabetic mice.
Dec 21, 2016
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2016 Dec 22. Epub 2016 Dec 22. PMID:
28017669
Article Published Date
: Dec 21, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
,
Depression
,
Diabetic Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Prophylactic Agents
[+]
Astaxanthin suppresses the neurological disorders induced by the K+ channel blocker kaliotoxin.
Apr 05, 2016
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2016 Apr 6. Epub 2016 Apr 6. PMID:
27052008
Article Published Date
: Apr 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragalin exerted antidepressant-like action through SIRT1 signalling modulated NLRP3 inflammasome deactivation.
Jan 19, 2020
Click here to read the entire abstract
Pubmed Data
: ACS Chem Neurosci. 2020 05 20 ;11(10):1495-1503. Epub 2020 May 4. PMID:
32364698
Article Published Date
: Jan 19, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Moringa oleifera
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice.
May 23, 2018
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2018 May 24. Epub 2018 May 24. PMID:
29795356
Article Published Date
: May 23, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Brain Inflammation
,
Depressive Disorder
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragaloside IV protects dopaminergic neuron from neuroinflammation and oxidative stress.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Oct ;75:105651. Epub 2019 Aug 8. PMID:
31401385
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Astragaloside IV supplementation attenuates cognitive impairment by inhibiting neuroinflammation and oxidative stress in type 2 diabetes.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2022 ;14:1004557. Epub 2022 Sep 29. PMID:
36247985
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Brain Inflammation
,
Diabetes: Cognitive Dysfunction
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Astragaloside might be a useful chemical in improving the spatial memory and relieving the oxidative stress and neuroinflammation in Alzheimer patients.
Mar 29, 2018
Click here to read the entire abstract
Pubmed Data
: Chin Med Sci J. 2018 Mar 30 ;33(1):29-37. PMID:
29620512
Article Published Date
: Mar 29, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Azadirachta indica ameliorates mouse hepatitis virus-induced neuroinflammatory demyelination.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cell Neurosci. 2020 ;14:116. Epub 2020 May 12. PMID:
32477069
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Neem
Diseases
:
Brain Inflammation
,
Hepatitis
,
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiviral Agents
[+]
B vitamins had the potential for treatment of neuroinflammation and neuroregeneration.
Dec 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Dec 17 ;24(24). Epub 2019 Dec 17. PMID:
31861069
Article Published Date
: Dec 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pantothenic Acid (Vitamin B-5)
,
Riboflavin (Vitamin B-2)
,
Thiamine (B-1)
,
Vitamin B-12
,
Vitamin B-3 (Niacin)
,
Vitamin B-6
Diseases
:
Brain Inflammation
,
Nerve Injuries
,
Neurodegenerative Diseases
,
Peripheral Nerve Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Baicalein is a promising novel analgesic agent for cancer-induced bone pain.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:973524. Epub 2015 Nov 15. PMID:
26649065
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
Diseases
:
Brain Inflammation
,
Cancer: Pain
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalein may be effective in the treatment of Parkinson's disease through anti-neuroinflammation.
Aug 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Sep ;50:38-47. Epub 2017 Jun 15. PMID:
28623717
Article Published Date
: Aug 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baicalin ameliorates cognitive impairment and protects microglia from LPS-induced neuroinflammation.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2020 ;2020:4751349. Epub 2020 Sep 22. PMID:
33029280
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bamboo extracts could be useful in treating HIV driven brain inflammation.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J HIV AIDS. 2016 May ;2(3). Epub 2016 May 11. PMID:
27398410
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Brain Inflammation
,
HIV Infections
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Bee pollen and propolis protect against neuroinflammation in the rodent model of autism.
Nov 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Lipids Health Dis. 2019 Nov 16 ;18(1):200. Epub 2019 Nov 16. PMID:
31733650
Article Published Date
: Nov 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Bee
Diseases
:
Autism
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bee pollen can be used safely to ameliorate oxidative stress, neuroinflammation, poor detoxification, and abnormal gut microbiota.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2016 ;16(1):120. Epub 2016 Apr 23. PMID:
27107819
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bee Pollen
Diseases
:
Autistic Disorder
,
Brain Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Microbiota
[+]
Bee venom could be considered a potential therapeutic or preventive agent for PD and other neuroinflammatory associated disorders.
Jul 27, 2016
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2016 Jul 28. Epub 2016 Jul 28. PMID:
27469335
Article Published Date
: Jul 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Berberine ameliorates depression-like behaviors.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2023 Mar 1 ;20(1):54. Epub 2023 Mar 1. PMID:
36859349
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process.
Jan 02, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Jan 3 ;87:200-208. Epub 2017 Jan 3. PMID:
28061403
Article Published Date
: Jan 02, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Brain Inflammation
,
Epilepsy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Berberine attenuates experimental autoimmune encephalomyelitis in mice.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(10):e13489. Epub 2010 Oct 19. PMID:
20976070
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Blood-Brain-Barrier Disorders
,
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Berberine could alleviate postoperative cognitive dysfunction by suppressing neuroinflammation in aged mice.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Jul 1 ;38:426-433. Epub 2016 Jul 1. PMID:
27376853
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Postoperative Recovery
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine could significantly improve the spatial learning and memory abilities of rats with vascular cognitive impairment.
Jul 27, 2019
Click here to read the entire abstract
Pubmed Data
: Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2019 Jul 28 ;35(4):359-362. PMID:
31701723
Article Published Date
: Jul 27, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Berberine treatment improved short-term memory in hyperlipidemia.
Oct 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Neurourol J. 2019 Nov ;23(Suppl 2):S102-110. Epub 2019 Nov 30. PMID:
31795609
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Brain Inflammation
,
Hyperlipidemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticholesteremic Agents
,
Hypolipidemic
[+]
Betulinic acid attenuates cognitive dysfunction, oxidative stress, and inflammation in a model of T-2 toxin-induced brain damage.
Mar 06, 2022
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2022 Mar 7. Epub 2022 Mar 7. PMID:
35254615
Article Published Date
: Mar 06, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Brain Damage
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Betulinic acid restores hippocampal cAMP/cGMP and BDNF, improves cerebral blood flow and recovers memory deficits.
May 16, 2018
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2018 May 17 ;832:56-66. Epub 2018 May 17. PMID:
29778746
Article Published Date
: May 16, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Dementia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
[+]
Bioactive components from garlic on brain resiliency against neuroinflammation and neurodegeneration.
Jan 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2020 Feb ;19(2):1554-1559. Epub 2019 Dec 27. PMID:
32010338
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Brain Inflammation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Biochanin A has been shown to have neuroprotective effects in cerebral ischemia/reperfusion.
Jan 14, 2015
Click here to read the entire abstract
Pubmed Data
: J Neurol Sci. 2015 Jan 15 ;348(1-2):121-5. Epub 2014 Nov 18. PMID:
25466482
Article Published Date
: Jan 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Brain Inflammation
,
Brain Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A protects against angiotensin II-induced damage of dopaminergic neurons.
Jan 11, 2019
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2019 12 ;30(8):700-711. PMID:
31703032
Article Published Date
: Jan 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Brain Inflammation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A reduces inflammatory injury and neuronal apoptosis following subarachnoid hemorrhage.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Behav Neurol. 2018 ;2018:1960106. Epub 2018 Jun 3. PMID:
29971136
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Brain Inflammation
,
Subarachnoid hemorrhage
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Bisphenol A exposure induces increased microglia and microglial related factors in the murine embryonic dorsal telencephalon and hypothalamus.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Lett. 2018 Mar 1 ;284:113-119. Epub 2017 Dec 14. PMID:
29248573
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Prenatal Chemical Exposures
Problem Substances
:
Bisphenol A
[+]
Black chokeberry has protective effects against the development of Alzheimer's disease.
Jan 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res Pract. 2018 Feb ;12(1):13-19. Epub 2018 Jan 15. PMID:
29399292
Article Published Date
: Jan 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
Prophylactic Agents
[+]
Blueberry anthocyanins extract attenuates acrylamide-induced oxidative stress and neuroinflammation.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2022 ;2022:7340881. Epub 2022 May 23. PMID:
35651724
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
Diseases
:
Brain Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
Problem Substances
:
Acrylamide
[+]
Blueberry attenuates microglial activation in the brain suggesting it may attenuate age-induced inflammation.
Dec 14, 2009
Click here to read the entire abstract
Pubmed Data
: Glia. 2009 Dec 14. PMID:
20014277
Article Published Date
: Dec 14, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Aging: Brain
,
Brain: Microglial Activation
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
[+]
Boron could protect against acrylamide induced oxidative stress and inflammation.
Jun 14, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Jun 15. Epub 2018 Jun 15. PMID:
29913234
Article Published Date
: Jun 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Boron
Diseases
:
Acrylamide-induced toxicity
,
Brain Inflammation
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Hypolipidemic
Problem Substances
:
Acrylamide
[+]
Brain-selective mild hypothermia promotes long-term white matter integrity after ischemic stroke in mice.
Jan 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: CNS Neurosci Ther. 2018 12 ;24(12):1275-1285. Epub 2018 Sep 16. PMID:
30295998
Article Published Date
: Jan 11, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Brain Inflammation
,
Stroke: Ischemic
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Brazilian green propolis prevents cognitive decline into mild cognitive impairment in elderly people living at high altitude.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 ;63(2):551-560. PMID:
29630549
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Brazillian
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
Butyrate and dietary soluble fiber improves neuroinflammation associated with aging.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Immunol. 2018 ;9:1832. Epub 2018 Aug 14. PMID:
30154787
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Butyrate
,
Fiber
Diseases
:
Aging
,
Brain Inflammation
,
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Epigenetic Modification
[+]
C. asiatica treatment helps to prevent cerebral damage and maintain near normal cerebral function in diabetes.
Jun 24, 2020
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2020 Jun 25. Epub 2020 Jun 25. PMID:
32588370
Article Published Date
: Jun 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Caffeic acid phenethyl ester reversed cadmium-induced cell death in hippocampus and cortex and subsequent cognitive disorders.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2020 Oct ;144:111636. Epub 2020 Jul 30. PMID:
32739455
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Brain Inflammation
,
Cadmium Poisoning
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
Problem Substances
:
Cadmium
[+]
Caffeine may abrogate lipopolysaccharide-induced oxidative stress and neuroinflammation.
Nov 07, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomolecules. 2019 Nov 8 ;9(11). Epub 2019 Nov 8. PMID:
31717470
Article Published Date
: Nov 07, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Caffeine
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Calorie restriction protects neural stem cells from age-related deficits in the subventricular zone
Jan 07, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging (Albany NY). 2019 Jan 8 ;11(1):115-126. PMID:
30622221
Article Published Date
: Jan 07, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Aging: Brain
,
Brain Inflammation
Therapeutic Actions
:
Dietary Modification: Low Calorie Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Cannabidiol may have potential as a preventative treatment for Alzheimer's disease.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2014 ;42(4):1383-96. PMID:
25024347
Article Published Date
: Dec 31, 2013
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Cannabidiol-rich non-psychotropic Cannabis sativa L. oils attenuate peripheral neuropathy symptoms.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2023 May ;37(5):1924-1937. Epub 2022 Dec 30. PMID:
36583304
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
[+]
Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis.
Apr 30, 2009
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2009 May ;34(2):300-7. PMID:
19385063
Article Published Date
: Apr 30, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Aging
,
Aging: Brain
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Calcium Channel Blockers
,
Neuritogenic
,
Neuroprotective Agents
[+]
Cannabinoids may have therapeutic value in neurodegenerative conditions by preventing and/or reducing neuroinflammation.
Feb 22, 2007
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2007 Feb 23 ;144(4):1516-22. Epub 2006 Dec 18. PMID:
17178196
Article Published Date
: Feb 22, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Carnosic acid alleviates chlorpyrifos-induced oxidative stress and inflammation in mice cerebral and ocular tissues.
Jan 21, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2020 Jan 22. Epub 2020 Jan 22. PMID:
31965510
Article Published Date
: Jan 21, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Problem Substances
:
Chlorpyrifos
[+]
Carnosic acid may represent a novel therapeutic strategy to treat metabolic disease induced brain injury.
Jun 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Jul ;20(1):495-504. Epub 2019 May 27. PMID:
31180544
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Brain Inflammation
,
High Fat Diet
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
[+]
Carnosine prevents Aβ-induced oxidative stress and inflammation in microglial cells.
Jan 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cells. 2019 Jan 17 ;8(1). Epub 2019 Jan 17. PMID:
30658430
Article Published Date
: Jan 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carnosine
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Carvacrol attenuated neuroinflammation, oxidative stress and depression and anxiety like behaviors.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Avicenna J Phytomed. 2022 ;12(5):514-526. PMID:
36249457
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Anxiety
,
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Anxiety Agents
,
Antidepressive Agents
[+]
Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2020 Jan ;24(1):27-37. Epub 2020 Dec 20. PMID:
31908572
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Chamomile decoction mitigates high fat diet-induced anxiety-like behavior, neuroinflammation and cerebral ROS overload.
Dec 13, 2020
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2020 Dec 14:1-12. Epub 2020 Dec 14. PMID:
33314994
Article Published Date
: Dec 13, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chamomile
Diseases
:
Anxiety
,
Brain Inflammation
,
High Fat Diet
,
Obesity
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Inflammatory Agents
[+]
Chicoric acid prevents neuroinflammation and neurodegeneration.
Feb 11, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 Feb 12 ;23(4). Epub 2022 Feb 12. PMID:
35216146
Article Published Date
: Feb 11, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Chicoric Acid
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Gut-brain Axis
[+]
Chronic consumption of alcohol in combination with energy drinks causes an inflammatory response and oxidative stress.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2016 ;2016:8725354. Epub 2016 Mar 16. PMID:
27069534
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Alcohol Toxicity
,
Brain Inflammation
,
Oxidative Stress
Problem Substances
:
Energy Drinks
[+]
Chronic consumption of γ-oryzanol can revert the LPS-induced cognitive and memory impairments by promoting hippocampal antioxidant and anti-inflammatory molecular responses.
Mar 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Mar 29 ;11(4). Epub 2019 Mar 29. PMID:
30934852
Article Published Date
: Mar 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gamma-Oryzanol
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Chronic exposure to aspartame results in oxidative stress in the brain of albino rats, as well as methanol formation.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Biosci. 2012 Sep ;37(4):679-88. PMID:
22922192
Article Published Date
: Aug 31, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Excitotoxicity
,
Lipid Peroxidation
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation.
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Neurochem. 2007 Aug;102(3):761-72. Epub 2007 May 4. PMID:
17488274
Article Published Date
: Aug 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Lithium
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Chronic oral palmitoylethanolamide administration rescues cognitive deficit.
Feb 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Med. 2020 Feb 5 ;9(2). Epub 2020 Feb 5. PMID:
32033363
Article Published Date
: Feb 04, 2020
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Palmitoylethanolamide
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Chronic T. gondii infection promotes neuroinflammation through cytokine networks and induces pathological progression of Alzheimer's disease.
Aug 10, 2016
Click here to read the entire abstract
Pubmed Data
: J Parasitol. 2016 Aug 11. Epub 2016 Aug 11. PMID:
27513205
Article Published Date
: Aug 10, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Toxoplasma gondii Infection
Additional Keywords
:
Increased Risk
[+]
Chrysanthemum indicum might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseases
Jan 01, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Jan 2. Epub 2019 Jan 2. PMID:
30610932
Article Published Date
: Jan 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Aging: Brain
,
Brain Inflammation
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Chrysin prevents cognitive and hippocampal long-term potentiation deficits and inflammation in rat with cerebral hypoperfusion and reperfusion injury.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Jun 1 ;226:202-209. Epub 2019 Apr 13. PMID:
30991061
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Brain Inflammation
,
Brain Ischemia
,
Cerebral Hypoperfusion
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Chrysin restores MPTP induced neuroinflammation, oxidative stress and neurotrophic factors in an acute Parkinson's disease mouse model.
Sep 13, 2019
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2019 Sep 14 ;709:134382. Epub 2019 Jul 17. PMID:
31325581
Article Published Date
: Sep 13, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Consumption of blueberries may reverse some age-related deficits in cognition.
Feb 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Gerontol A Biol Sci Med Sci. 2019 Feb 17. Epub 2019 Feb 17. PMID:
30772901
Article Published Date
: Feb 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Aging: Brain
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Coriandrum sativum attenuates microglia mediated neuroinflammation.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EXCLI J. 2021 ;20:835-850. Epub 2021 Apr 28. PMID:
34177406
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Coriandrum sativum
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Crocetin promotes clearance of amyloid-β by inducing autophagy.
Jan 18, 2021
Click here to read the entire abstract
Pubmed Data
: Autophagy. 2021 Jan 19:1-20. Epub 2021 Jan 19. PMID:
33404280
Article Published Date
: Jan 18, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Crocetin
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Autophagy Up-regulation
,
Neuroprotective Agents
[+]
Crocin may have improvement effects on cholestasis-induced neuroinflammation in the rat's striatum.
May 20, 2021
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2021 May 21. Epub 2021 May 21. PMID:
34019207
Article Published Date
: May 20, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Curcumin ameliorates hypertension via gut-brain communication in spontaneously hypertensive rat.
Oct 14, 2021
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2021 Oct 15 ;429:115701. Epub 2021 Aug 25. PMID:
34453990
Article Published Date
: Oct 14, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Inflammation
,
Hypertension
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Gut-brain Axis
[+]
Curcumin and piperine afforded a better neuroprotective effect compared to each of them alone.
Nov 15, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2016 Nov 16. Epub 2016 Nov 16. PMID:
27853890
Article Published Date
: Nov 15, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Piperine
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Anti-Inflammatory Agents
,
Brain Inflammation
,
CURCUMIN
,
Interleukin-1 beta downregulation
,
Natural Substance Synergy
,
Parkinson's disease
,
Piperine
[+]
Curcumin and piperine showed strong antioxidant and protective effect against QA-induced behavioural and neurological alteration.
Jan 29, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacology. 2016 Jan 30 ;97(3-4):151-160. Epub 2016 Jan 30. PMID:
26828892
Article Published Date
: Jan 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Piperine
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Natural Substance Synergy
[+]
Curcumin can attenuate the downregulation of CISD2 in spinal cord injuries and LPS-treated astrocytes.
Aug 07, 2015
Click here to read the entire abstract
Pubmed Data
: Injury. 2015 Aug 8. Epub 2015 Aug 8. PMID:
26387034
Article Published Date
: Aug 07, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Inflammation
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
MicroRNA modulator
,
Neuroprotective Agents
[+]
Curcumin has neuroprotective effects in traumatic brain injury models.
Mar 02, 2023
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2023 Mar 3. Epub 2023 Mar 3. PMID:
36872351
Article Published Date
: Mar 02, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
[+]
Curcumin is effective in attenuating glial activation and ameliorates cognitive deficits in chronic epilepsy.
Jul 15, 2015
Click here to read the entire abstract
Pubmed Data
: Neurochem Int. 2015 Jul 16. Epub 2015 Jul 16. PMID:
26190183
Article Published Date
: Jul 15, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Epilepsy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Curcumin may be beneficial in the treatment of acute stress induced anxiety and enhancement of memory function.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2015 Jun ;115:1-8. Epub 2015 Apr 11. PMID:
25869755
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Anxiety Disorders
,
Brain Inflammation
,
Stress
Pharmacological Actions
:
Anti-Anxiety Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Curcumin protects pre-oligodendrocytes from activated microglia, indicating it may play a role in protecting against preterm periventricular leukomalacia (PVL).
Jun 21, 2010
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2010 Jun 21;1339:60-9. Epub 2010 Apr 24. PMID:
20403340
Article Published Date
: Jun 21, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Preterm Periventricular Leukomalacia (PVL)
Pharmacological Actions
:
Apoptotic
,
Enzyme Inhibitors
,
Neuroprotective Agents
[+]
Curcumin treatment attenuates ischemic stroke-induced brain injury via activation of SIRT1.
Nov 26, 2015
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2015 Nov 27. Epub 2015 Nov 27. PMID:
26639783
Article Published Date
: Nov 26, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Inflammation
,
Mitochondrial Dysfunction
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
SIRT1 Activator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin treatment significantly improved the neurological status evaluated during 2 weeks after brain injury.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Pharmacol Biochem Behav. 2013 Sep ;110:238-44. Epub 2013 Aug 7. PMID:
23932920
Article Published Date
: Aug 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Inflammation
,
Brain Injury: Traumatic
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
Additional Keywords
:
Significant Treatment Outcome
[+]
Daily e-cigarette use may cause neuroinflammation, which may contribute to behavioral changes and mood disorders.
Apr 11, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Elife. 2022 Apr 12 ;11. Epub 2022 Apr 12. PMID:
35411847
Article Published Date
: Apr 11, 2022
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Cardiovascular Diseases
,
Gastrointestinal Inflammation
,
Inflammation
,
Mood Disorders
Additional Keywords
:
Risk Factors
Problem Substances
:
Electronic Cigarettes
Adverse Pharmacological Actions
:
Inflammatory
[+]
Dates alleviate lipopolysaccharide-induced sickness behaviour.
Jun 20, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Jun 21 ;24(13). Epub 2023 Jun 21. PMID:
37445591
Article Published Date
: Jun 20, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury.
Jan 09, 2020
Click here to read the entire abstract
Pubmed Data
: J Control Release. 2020 07 10 ;323:361-375. Epub 2020 Apr 24. PMID:
32339548
Article Published Date
: Jan 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Sinomenine
Diseases
:
Brain Inflammation
,
Brain Injury: Traumatic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Depressive-like phenotype evoked by lifelong nutritional omega-3 deficiency.
Jan 23, 2020
Click here to read the entire abstract
Pubmed Data
: Brain Behav Immun. 2020 Jan 24. Epub 2020 Jan 24. PMID:
31987923
Article Published Date
: Jan 23, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Omega-3 Fatty Acids
Diseases
:
Brain Inflammation
,
Depression
,
Omega-3 Fatty Acid Deficiency
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Increased Risk
[+]
DHA-rich fish oil and Tualang honey can be effective in lowering pro-inflammatory cytokine levels in the brains of rats under chronic stress conditions.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Taibah Univ Med Sci. 2019 Aug ;14(4):317-323. Epub 2019 Jul 23. PMID:
31488962
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
Tualang Honey
Diseases
:
Brain Inflammation
,
Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diallyl disulfide administration prevents and reveres lipopolysaccharide-induced depression-like behaviours.
Jul 31, 2021
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2021 Aug ;44(4):1381-1395. Epub 2021 Jan 29. PMID:
33511484
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Organosulfur Compounds
Diseases
:
Brain Inflammation
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Antioxidants
[+]
Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury.
Aug 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Neurotrauma. 2008 Aug;25(8):975-83. PMID:
18665805
Article Published Date
: Aug 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Choline
Diseases
:
Brain Inflammation
,
Traumatic Brain Injury
[+]
Dietary curcumin ameliorates aging-related cerebrovascular dysfunction through the AMPK/uncoupling protein 2 pathway.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2013 ;32(5):1167-77. Epub 2013 Nov 11. PMID:
24335167
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Inflammation
,
Cerebrovascular Disorders
,
Ischemia
,
Neurodegenerative Diseases
,
Oxidative Stress
,
Stroke
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
Neurorestorative
[+]
Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation.
Jun 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Microbiome. 2019 Jun 29 ;7(1):98. Epub 2019 Jun 29. PMID:
31255176
Article Published Date
: Jun 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Essential Fatty Acids
Diseases
:
Brain Inflammation
,
Dysbiosis
,
High Fructose Diet
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Neuroprotective Agents
[+]
Dietary intervention with the gut microbial metabolite urolithin A attenuates lipopolysaccharide-induced neuroinflammation and cognitive deficits.
Mar 28, 2023
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2023 Mar 29:e2200401. Epub 2023 Mar 29. PMID:
36987793
Article Published Date
: Mar 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Urolithin A
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diosmin could be considered as potential candidate for novel anti-Alzheimer's disease therapy.
Jan 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroimmunol. 2016 10 15 ;299:98-106. Epub 2016 Sep 1. PMID:
27725131
Article Published Date
: Jan 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Dried peel powder of C. kawachiensis exerts anti-inflammatory and neuroprotective effects in the brain.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2018 Aug ;82(8):1384-1395. Epub 2018 May 6. PMID:
29732953
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Citrus Peel
Diseases
:
Brain Inflammation
,
Diabetic Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Early hyperbaric oxygen treatment attenuates burn-induced neuro-inflammation.
Jul 26, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Jul 27 ;19(8). Epub 2018 Jul 27. PMID:
30060489
Article Published Date
: Jul 26, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Burns: Severe
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Echinacoside protects dopaminergic neurons.
Aug 22, 2020
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2020 Aug 23 ;164:55-64. Epub 2020 Aug 23. PMID:
32846198
Article Published Date
: Aug 22, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Echinacea
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Effect of seabuckthorn seed protein and its arginine-enriched peptides on combating memory impairment.
Mar 30, 2023
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2023 Mar 31 ;232:123409. Epub 2023 Jan 24. PMID:
36706884
Article Published Date
: Mar 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
,
Sea buckthorn
Diseases
:
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Effects of Hericium erinaceus mycelium extracts on the functional activity of purinoceptors and neuropathic pain.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2020 ;2020:2890194. Epub 2020 May 13. PMID:
32508945
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Brain Inflammation
,
Neuropathic Pain
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
[+]
Effects of orally administered cannabidiol on neuroinflammation and intestinal inflammation.
Nov 09, 2021
Click here to read the entire abstract
Pubmed Data
: J Neuroimmune Pharmacol. 2021 Nov 10. Epub 2021 Nov 10. PMID:
34757526
Article Published Date
: Nov 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Autoimmune Diseases
,
Brain Inflammation
,
Gastrointestinal Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
EGCG can attenuate high-fat-induced hypothalamic inflammation.
Oct 12, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Oct 13 ;20(20). Epub 2019 Oct 13. PMID:
31614951
Article Published Date
: Oct 12, 2019
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
EGCG has a beneficial effect on impaired adult neurogenesis caused by lipopolysaccharide induced neuro-inflammation.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2016 Jan ;20(1):41-51. Epub 2015 Dec 31. PMID:
26807022
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Electro-acupuncture alleviates chronic unpredictable stress-induced depressive- and anxiety-like behaviour and neuroinflammation.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Mol Neurosci. 2018 ;11:149. Epub 2018 May 31. PMID:
29946236
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Depression
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-18 down-regulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Electroacupuncture alleviates postoperative cognitive dysfunction in aged rats.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2017 ;2017:6421260. Epub 2017 Jun 8. PMID:
28684969
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Postoperative Recovery
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Electroacupuncture alleviates postoperative pain through inhibiting neuroinflammation.
Jul 04, 2023
Click here to read the entire abstract
Pubmed Data
: J Integr Med. 2023 Jul 5. Epub 2023 Jul 5. PMID:
37517892
Article Published Date
: Jul 04, 2023
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Electroacupuncture ameliorates neuroinflammation-mediated cognitive deficits through inhibition.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Plast. 2021 ;2021:8814616. Epub 2021 Jan 6. PMID:
33505459
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: CNS Neurosci Ther. 2022 03 ;28(3):390-400. Epub 2021 Dec 23. PMID:
34951130
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Electroacupuncture attenuates cognition impairment via anti-neuroinflammation in an Alzheimer’s disease animal model
Dec 12, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2019 Dec 13 ;16(1):264. Epub 2019 Dec 13. PMID:
31836020
Article Published Date
: Dec 12, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Neuroprotective Agents
[+]
Electroacupuncture pre-treatment alleviates sepsis-induced brain injury by inhibition of microglial activation and attenuation of inflammation.
Oct 18, 2016
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2016 Oct 19 ;127:248-259. Epub 2016 Aug 19. PMID:
27771396
Article Published Date
: Oct 18, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Sepsis
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Catalase Up-Regulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Electroacupuncture pretreatment preserves telomerase reverse transcriptase function and alleviates postoperative cognitive dysfunction.
Jul 26, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: CNS Neurosci Ther. 2023 Jul 27. Epub 2023 Jul 27. PMID:
37501354
Article Published Date
: Jul 26, 2023
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Oxidative Stress
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Electroacupuncture prevents the depression-like behavior by inhibiting the NF-κB/NLRP3 inflammatory pathway.
Jan 10, 2022
Click here to read the entire abstract
Pubmed Data
: Neuropsychobiology. 2022 Jan 11:1-9. Epub 2022 Jan 11. PMID:
35016190
Article Published Date
: Jan 10, 2022
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Depression
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Electroacupuncture synergistically inhibits proinflammatory cytokine production and improves cognitive function.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:7992688. Epub 2021 Oct 1. PMID:
34630618
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ellagic acid inhibits neuroinflammation and cognitive impairment induced by lipopolysaccharides.
Aug 09, 2020
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2020 Aug 10. Epub 2020 Aug 10. PMID:
32779097
Article Published Date
: Aug 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ellagic acid prevents cognitive and hippocampal long-term potentiation deficits and brain inflammation in rat with traumatic brain injury.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2015 Mar 1 ;124:120-7. Epub 2015 Jan 28. PMID:
25637685
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Brain Inflammation
,
Memory Disorders
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
[+]
Emblica officinalis could be a promising therapeutic aid against aluminium-induced neurotoxicity.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2019 Feb ;35(2):318-330. Epub 2018 Sep 21. PMID:
30242626
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Amla Fruit
Diseases
:
Aluminum Toxicity
,
Brain Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
Problem Substances
:
Aluminum
[+]
Endurance exercise may exert neuroprotective effects by mitigating the production of pro-inflammatory cytokines.
Mar 15, 2016
Click here to read the entire abstract
Pubmed Data
: J Neuroendocrinol. 2016 Mar 16. Epub 2016 Mar 16. PMID:
26991447
Article Published Date
: Mar 15, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
High Fat Diet
Therapeutic Actions
:
Exercise: Endurance
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
EPA and GLA attenuate interleukin-1 beta-induced brain inflammation in rats.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 May;138(5):954-63. PMID:
18424607
Article Published Date
: May 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Interleukin-1 beta downregulation
[+]
Epigallocatechin-3-gallate-loaded liposomes favour anti-inflammation of microglia cells and promote neuroprotection.
Mar 15, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2021 Mar 16 ;22(6). Epub 2021 Mar 16. PMID:
33809762
Article Published Date
: Mar 15, 2021
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Brain Inflammation
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments.
Oct 02, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Oct 3 ;66(39):10205-10214. Epub 2018 Sep 21. PMID:
30208700
Article Published Date
: Oct 02, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Eriodictyol
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Exercise three times a week was effective at reversing serum and brain RANTES and MCP-1 expression to the levels of controls.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2016 Jan 1 ;610:165-70. Epub 2015 Nov 4. PMID:
26547034
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Dose Response
,
Risk Reduction
[+]
Exposure to ambient dusty particulate matter impairs spatial memory and hippocampal LTP by increasing brain inflammation and oxidative stress.
Dec 20, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Dec 21:117210. Epub 2019 Dec 21. PMID:
31874166
Article Published Date
: Dec 20, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Air Pollution Linked Toxicity
,
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Memory Disorders
Additional Keywords
:
Risk Factors
[+]
Extracts of R. officinalis and rosmarinic acid through modulating neuro-inflammation might be potential candidates in treating neuropathic pain.
Dec 21, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Dec 22 ;86:441-449. Epub 2016 Dec 22. PMID:
28012923
Article Published Date
: Dec 21, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Rosemary
,
Rosmarinic acid
Diseases
:
Brain Inflammation
,
Neuropathic Pain
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin PGE2 downregulation
Additional Keywords
:
Plant Extracts
[+]
F. mume is a potentially valuable drug or nutraceutical for the treatment of vascular dementia.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2016 Feb ;19(2):196-204. Epub 2015 Dec 29. PMID:
26714236
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ume (Japanese apricot)
Diseases
:
Brain Inflammation
,
Cerebral Hypoperfusion
,
Dementia
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
F. mume is potentially an effective therapeutic for the treatment of vascular dementia.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15:125. Epub 2015 Apr 22. PMID:
25898017
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ume (Japanese apricot)
Diseases
:
Brain Inflammation
,
Brain Ischemia
,
Cerebral Hypoperfusion
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Phytotherapy
[+]
Fermentation enhances Ginkgo biloba protective role on gamma-irradiation induced inflammatory gene expression and stress hormones in rat brain.
Mar 03, 2016
Click here to read the entire abstract
Pubmed Data
: J Photochem Photobiol B. 2016 Mar 4 ;158:154-163. Epub 2016 Mar 4. PMID:
26974576
Article Published Date
: Mar 03, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Ginkgo biloba
Diseases
:
Brain Inflammation
,
Chemotherapy and Radiation Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Radioprotective
[+]
Ferulic acid inhibits neuro-inflammation in mice exposed to chronic unpredictable mild stress.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Apr ;45:128-134. Epub 2017 Feb 14. PMID:
28213267
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ferulic acid
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
NF-kappaB Inhibitor
Problem Substances
:
Fluoxetine (trade name Prozac)
[+]
Ferulic acid produces neuroprotection against radiation-induced neuroinflammation.
Apr 20, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Radiat Biol. 2022 Apr 21:1-10. Epub 2022 Apr 21. PMID:
35445640
Article Published Date
: Apr 20, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ferulic acid
Diseases
:
Brain Inflammation
,
Radiotherapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Fisetin ameliorates cognitive impairment by activating mitophagy and suppressing neuroinflammation in rats with sepsis-associated encephalopathy.
Nov 26, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: CNS Neurosci Ther. 2021 Nov 27. Epub 2021 Nov 27. PMID:
34837343
Article Published Date
: Nov 26, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fisetin may be beneficial in age-related neurological disorders.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:612078. Epub 2021 Feb 25. PMID:
33716741
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Fisetin may be developed as a potential nutritional target for the prevention of lead-induced neurotoxicity.
Sep 16, 2019
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2019 Sep 17 ;134:110824. Epub 2019 Sep 17. PMID:
31539617
Article Published Date
: Sep 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Brain Inflammation
,
Lead Poisoning
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Lead
[+]
Fish oil supplementation attenuates cognitive impairment by inhibiting neuroinflammation in STZ-induced diabetes.
Aug 03, 2020
Click here to read the entire abstract
Pubmed Data
: Aging (Albany NY). 2020 Aug 4 ;12. Epub 2020 Aug 4. PMID:
32756005
Article Published Date
: Aug 03, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fish Oil
Diseases
:
Brain Inflammation
,
Diabetes: Cognitive Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Formononetin could improve the cognitive function by inhibiting neuroinflammation.
Aug 06, 2019
Click here to read the entire abstract
Pubmed Data
: CNS Neurol Disord Drug Targets. 2019 Aug 7. Epub 2019 Aug 7. PMID:
31389320
Article Published Date
: Aug 06, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Formononetin
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
High Fat Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Formononetin protects against inflammation associated with cerebral ischemia-reperfusion injury.
Mar 23, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Mar 24 ;149:112836. Epub 2022 Mar 24. PMID:
35339827
Article Published Date
: Mar 23, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Formononetin
Diseases
:
Brain Inflammation
,
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Gallic acid attenuated lipopolysaccharide-induced neuroinflammation.
Dec 11, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2019 Dec 12. Epub 2019 Dec 12. PMID:
31832973
Article Published Date
: Dec 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gallic Acid
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Ganoderic acid A alleviated the depressive-like behaviors and brain inflammation in post-stroke depression.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropsychiatr Dis Treat. 2021 ;17:2671-2681. Epub 2021 Aug 14. PMID:
34421302
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Brain Inflammation
,
Depression
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Ganoderic acid A To alleviate neuroinflammation of Alzheimer's disease.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2021 Dec 1 ;69(47):14204-14214. Epub 2021 Nov 19. PMID:
34798773
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Immunomodulatory
,
Neuroprotective Agents
[+]
Gardasil via its Al adjuvant and HPV antigens has the ability to trigger neuroinflammation and autoimmune reactions.
Jul 15, 2016
Click here to read the entire abstract
Pubmed Data
: Immunol Res. 2016 Jul 16. Epub 2016 Jul 16. PMID:
27421722
Article Published Date
: Jul 15, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Autoimmune Diseases
,
Brain Inflammation
Anti Therapeutic Actions
:
Vaccination: HPV (Gardasil)
[+]
Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Theranostics. 2022 ;12(3):1220-1246. Epub 2022 Jan 1. PMID:
35154484
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Brain Inflammation
,
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Exosomes
[+]
Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation.
Feb 04, 2021
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2021 Feb 5 ;892:173734. Epub 2020 Nov 18. PMID:
33220272
Article Published Date
: Feb 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Aging: Brain
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Gastrodin ameliorates depression-like behaviors and up-regulates proliferation of hippocampal-derived neural stem cells.
May 31, 2014
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2014 Jun 1 ;266:153-60. Epub 2014 Mar 5. PMID:
24613238
Article Published Date
: May 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Gastrodin can significantly relieve the Tourette syndrome induced by DOI in rats.
Feb 19, 2019
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2019 Feb 20:e22302. Epub 2019 Feb 20. PMID:
30790395
Article Published Date
: Feb 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Brain Inflammation
,
Tourette Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Gastrodin From Gastrodia elata enhances cognitive function and neuroprotection.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:814271. Epub 2022 Jun 2. PMID:
35721206
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Neuroprotective Agents
Additional Keywords
:
Gut-brain Axis
[+]
Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model.
Feb 14, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2012 Feb 15 ;7(5):325-31. PMID:
25774170
Article Published Date
: Feb 14, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Genipin, a compound found within gardenia fruit, inhibits microglial activation in a mouse model of brain inflammation.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2010 Feb 1. Epub 2010 Feb 1. PMID:
20123040
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Gardenia
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Genistein attenuates acute cerebral ischemic damage.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Aging Neurosci. 2020 ;12:153. Epub 2020 Jun 17. PMID:
32625078
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Brain Inflammation
,
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Genistein is able to regulate the gut microbiota, reducing metabolic endotoxemia and decreasing the neuroinflammatory response in a high fat diet.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2018 08 ;62(16):e1800313. Epub 2018 Jul 29. PMID:
29979819
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Brain Inflammation
,
High Fat Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Genistein prevents hypoxia-induced cognitive dysfunctions by ameliorating oxidative stress and inflammation in the hippocampus.
Mar 18, 2021
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2021 Mar 19. Epub 2021 Mar 19. PMID:
33740236
Article Published Date
: Mar 18, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Hypoxia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Genistein protects against spinal cord injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Appl Bionics Biomech. 2022 ;2022:4790344. Epub 2022 Apr 22. PMID:
35498148
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Brain Inflammation
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Genistein supplementation alleviated neuroinflammation and peripheral and brain insulin resistance.
Oct 30, 2016
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Nutrients. 2016 Oct 31 ;8(11). Epub 2016 Oct 31. PMID:
27809235
Article Published Date
: Oct 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Brain Inflammation
,
High Fat Diet
,
Insulin Resistance
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginger inhibits micoglial cell activiation associated with brain inflammation.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2009 Jun;47(6):1190-7. Epub 2009 Feb 20. PMID:
19233241
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin Antagonists
[+]
Gingerol-enriched ginger supplementation mitigates neuropathic pain.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Front Pharmacol. 2022 ;13:912609. Epub 2022 Jul 8. PMID:
35873544
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Brain Inflammation
,
Neuropathic Pain
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Gut-brain Axis
[+]
Ginkgetin can significantly reduce plasma Aβ levels by 59% and Aβ plaque by 51% in the brain of transgenic mice.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Prev Alzheimers Dis. 2016 ;3(1):24-29. PMID:
29214278
Article Published Date
: Dec 31, 2015
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginkgo biloba extract has potential therapeutic effects in relieving depressive status of patients with heart failure.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropsychiatr Dis Treat. 2019 ;15:3041-3050. Epub 2019 Oct 29. PMID:
31754303
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Brain Inflammation
,
Depression
,
Heart Failure
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginkgo biloba extract has specific neuroprotective effects that may be useful for the treatment of chronic cerebral hypoperfusion.
Nov 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytomedicine. 2016 Nov 15 ;23(12):1356-1364. Epub 2016 Aug 1. PMID:
27765355
Article Published Date
: Nov 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Brain Inflammation
,
Cerebral Hypoperfusion
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Ginkgo biloba extract improves cognitive function and regulates inflammatory responses in the APP/PS1 mouse.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Exp Gerontol. 2016 Aug ;81:92-100. Epub 2016 May 22. PMID:
27220811
Article Published Date
: Jul 31, 2016
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Ginkgolide B Alleviates Learning and Memory Impairment.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:676392. Epub 2021 Jun 17. PMID:
34220511
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Brain Inflammation
,
Dementia
,
Learning disorders
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ginkgolide B has protective effects on cerebral injury by inhibiting the inflammation induced by ischemia/reperfusion injury.
Mar 31, 2010
Click here to read the entire abstract
Pubmed Data
: Zhong Yao Cai. 2010 Apr ;33(4):578-80. PMID:
20845788
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Brain Inflammation
,
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginkgolide B improved postoperative cognitive dysfunction.
Jul 17, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Anesthesiol. 2022 Jul 18 ;22(1):229. Epub 2022 Jul 18. PMID:
35850641
Article Published Date
: Jul 17, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Postoperative Recovery
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress.
May 24, 2020
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2020 May 25:112710. Epub 2020 May 25. PMID:
32464121
Article Published Date
: May 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Ginsenoside has an anti-neuroinflammation effect in a rat model of Alzheimer disease.
Jan 03, 2011
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2011 Jan 3;487(1):70-2. Epub 2010 Oct 7. PMID:
20933058
Article Published Date
: Jan 03, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):499-507. Epub 2017 Jul 25. PMID:
31695559
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2019 Oct ;14(10):1814-1822. PMID:
31169200
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rg1 may have protective effects on neuroinflammation and neuronal injury induced by chronic glucocorticoids exposure.
Sep 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2017 Oct ;40(4):1134-1142. Epub 2017 Aug 9. PMID:
28849171
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
Problem Substances
:
Dexamethasone
[+]
Ginsenoside Rg3 alleviates lipopolysaccharide-induced learning and memory impairments.
Sep 29, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomol Ther (Seoul). 2013 Sep 30 ;21(5):381-90. PMID:
24244826
Article Published Date
: Sep 29, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 attenuates microglia activation following systemic lipopolysaccharide treatment in mice.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2012 ;35(9):1546-52. PMID:
22975507
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside-Rg1 mitigates cardiac arrest-induced cognitive damage.
Nov 30, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2022 Dec 1:175431. Epub 2022 Dec 1. PMID:
36463944
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Cardiac Arrest
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenosides Rb1 attenuates chronic social defeat stress-induced depressive behavior.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Nutr. 2022 ;9:868833. Epub 2022 May 12. PMID:
35634375
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
SIRT1 Activator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury.
Nov 15, 2010
Click here to read the entire abstract
Pubmed Data
: Glia. 2010 Nov 15 ;58(15):1881-92. PMID:
20737476
Article Published Date
: Nov 15, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Glucosamine
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions
:
Enzyme Inhibitors
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Glycyrrhizin attenuates hypoxic-ischemic brain damage by inhibiting ferroptosis and neuroinflammation.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2022 ;2022:8438528. Epub 2022 Apr 7. PMID:
35432719
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Glycyrrhizin
Diseases
:
Brain Inflammation
,
Brain Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Glycyrrhizin protects mice against experimental autoimmune encephalomyelitis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Immunol. 2018 ;9:1518. Epub 2018 Jul 2. PMID:
30013568
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Glycyrrhizin
Diseases
:
Brain Inflammation
,
Encephalomyelitis
,
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Glyphosate infiltrates the brain, elevates both the expression of TNFα and soluble Aβ.
Jul 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2022 Jul 28 ;19(1):193. Epub 2022 Jul 28. PMID:
35897073
Article Published Date
: Jul 27, 2022
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Glyphosate Toxicity
,
Neurodegenerative Diseases
Additional Keywords
:
Increased Risk
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Gotu Kola protected against sleep deprivation-induced anxiety-like behaviour, oxidative damage and neuroinflammation in mice.
Feb 04, 2016
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2016 Feb 5. Epub 2016 Feb 5. PMID:
26848139
Article Published Date
: Feb 04, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Anxiety Disorders
,
Brain Inflammation
,
Oxidative Stress
,
Sleep Disorders
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
GSPE pre-treatment protects against long-term cafeteria diet-induced mitochondrial and inflammatory affectations in the hippocampus.
Nov 17, 2021
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2021 Nov 18:1-11. Epub 2021 Nov 18. PMID:
34789070
Article Published Date
: Nov 17, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
Anti Therapeutic Actions
:
Western Diet
[+]
Gut bacteria regulate movement disorders in mice and suggest that alterations in the human microbiome represent a risk factor for PD.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell. 2016 Dec 1 ;167(6):1469-1480.e12. PMID:
27912057
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Dysbiosis
,
Parkinson's Disease
Additional Keywords
:
Microbiota
,
Risk Factors
[+]
H. sabdariffa is a potent anti-inflammatory substance that prevents impairments in spatial memory consolidation.
Oct 14, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Kobe J Med Sci. 2018 Oct 15 ;64(2):E73-E83. Epub 2018 Oct 15. PMID:
30381729
Article Published Date
: Oct 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Hibiscus sabdariffa
Diseases
:
Brain Inflammation
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Hericium erinaceus mycelium may be a potential health-promoting supplement for minimizing the progression of aging and obesity-induced neurodegeneration.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2019 May ;22(5):469-478. PMID:
31084539
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Aging
,
Brain Inflammation
,
High Fat Diet
,
High Sugar Diet
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuritogenic
,
Neuroprotective Agents
[+]
Hesperidin attenuates depression-related symptoms in mice with mild traumatic brain injury.
Nov 14, 2018
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2018 Nov 15 ;213:198-205. Epub 2018 Oct 21. PMID:
30352242
Article Published Date
: Nov 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Brain Inflammation
,
Brain Injury: Traumatic
,
Depression
,
Oxidative Stress
Pharmacological Actions
:
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hesperidin could reduce the incidence and severity of Multiple sclerosis.
Nov 25, 2016
Click here to read the entire abstract
Pubmed Data
: J Neuroimmunol. 2016 Nov 26. Epub 2016 Nov 26. PMID:
27912911
Article Published Date
: Nov 25, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
HFCS-55, negatively impacts hippocampal function, metabolic outcomes, and neuroinflammation when consumed in excess during the adolescent period of development.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Hippocampus. 2015 Feb ;25(2):227-39. Epub 2014 Oct 3. PMID:
25242636
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Learning disorders
Additional Keywords
:
Adolescent Development
Problem Substances
:
High Fructose Corn Syrup
Adverse Pharmacological Actions
:
Inflammatory
[+]
High selenium yeast mitigates aluminum-induced cerebral inflammation.
Jul 15, 2018
Click here to read the entire abstract
Pubmed Data
: Biometals. 2018 Jul 16. Epub 2018 Jul 16. PMID:
30014352
Article Published Date
: Jul 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Selenium
Diseases
:
Aluminum Toxicity
,
Brain Inflammation
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Aluminum
[+]
Hippocampal derangements triggered by high fat-high fructose diet feeding were effectively curtailed by apigenin.
Feb 22, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Feb 23 ;89:323-331. Epub 2017 Feb 23. PMID:
28237914
Article Published Date
: Feb 22, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Brain Inflammation
,
High Fat Diet
,
High Fructose Diet
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Honokiol attenuates the memory impairments, oxidative stress, neuroinflammation, and GSK-3β activation in vascular dementia rats.
Jul 15, 2019
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2019 Jul 16. Epub 2019 Jul 16. PMID:
31322570
Article Published Date
: Jul 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Honokiol may be a potential therapeutic approach for Alzheimer's disease.
Aug 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Exp Ther. 2018 Sep ;366(3):470-478. Epub 2018 Jul 10. PMID:
29991481
Article Published Date
: Aug 31, 2018
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.
Jan 11, 2017
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2017 12 ;32(6):1861-1869. Epub 2017 Jul 26. PMID:
28748496
Article Published Date
: Jan 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Huperzine
Diseases
:
Brain Inflammation
,
Brain Injury: Traumatic
,
Learning disorders
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Neurosci Res. 2010 Mar;88(4):807-15. PMID:
19795377
Article Published Date
: Mar 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Huperzine
Diseases
:
Brain Inflammation
,
Cerebral Hypoperfusion
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function.
Sep 18, 2016
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2016 Sep 19 ;631:70-8. Epub 2016 Jul 9. PMID:
27400829
Article Published Date
: Sep 18, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Huperzine
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Hydrogen rich water could exert a neuroprotective effect against traumatic brain injury and attenuate inflammation.
Apr 14, 2016
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2016 Apr 15 ;1637:1-13. Epub 2016 Jan 26. PMID:
26826009
Article Published Date
: Apr 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Brain Inflammation
,
Brain Injury: Traumatic
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-10 downregulation
,
Neuroprotective Agents
[+]
Hydrogen-rich water had beneficial effects on depressive-like behaviour and may be mediated by suppression of the inflammasome activation.
Mar 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Mar 30 ;6:23742. Epub 2016 Mar 30. PMID:
27026206
Article Published Date
: Mar 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
[+]
Hydroxysafflor yellow A can improve depressive behavior by inhibiting hippocampal inflammation and oxidative stress through regulating HPA axis.
Dec 31, 2021
Click here to read the entire abstract
Pubmed Data
: J Biosci. 2022 ;47. PMID:
35092409
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Safflower
Diseases
:
Brain Inflammation
,
Depression
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Hydroxytyrosol alleviates oxidative stress and neuroinflammation and enhances hippocampal neurotrophic signaling.
May 16, 2021
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2021 May 17. Epub 2021 May 17. PMID:
33998633
Article Published Date
: May 16, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Antioxidants
[+]
Hyperbaric oxygen therapy treatment may ameliorate TBI-induced depression-like behaviour in rats by attenuating neuro-inflammation.
Jan 04, 2017
Click here to read the entire abstract
Pubmed Data
: World Neurosurg. 2017 Jan 5. Epub 2017 Jan 5. PMID:
28065873
Article Published Date
: Jan 04, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Traumatic Brain Injury
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hypericum perforatum nanoemulsion mitigates cisplatin-induced chemobrain.
Feb 07, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxics. 2023 Feb 8 ;11(2). Epub 2023 Feb 8. PMID:
36851034
Article Published Date
: Feb 07, 2023
Study Type
: Animal Study
Additional Links
Substances
:
St. Johns Wort
Diseases
:
Brain Inflammation
,
Chemobrain
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress.
Mar 15, 2021
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2021 Mar 16:1-11. Epub 2021 Mar 16. PMID:
33722183
Article Published Date
: Mar 15, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hypothalamic inflammation was susceptible to exercise and diet.
Jun 08, 2020
Click here to read the entire abstract
Pubmed Data
: Aging (Albany NY). 2020 Jun 9 ;12. Epub 2020 Jun 9. PMID:
32518216
Article Published Date
: Jun 08, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Memory Disorders
Therapeutic Actions
:
Exercise: Swimming
Pharmacological Actions
:
Neuroprotective Agents
[+]
Icariin alleviates autistic-like behavior, hippocampal inflammation and vGlut1 expression in adult BTBR mice.
May 07, 2023
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2023 May 8 ;445:114384. Epub 2023 Mar 6. PMID:
36889463
Article Published Date
: May 07, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Icariin
Diseases
:
Autism Spectrum Disorders
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Icariin ameliorates the progression of experimental autoimmune encephalomyelitis.
Oct 14, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Oct 15 ;885:173523. Epub 2020 Aug 29. PMID:
32871176
Article Published Date
: Oct 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Icariin
Diseases
:
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Icariin reduces cognitive dysfunction induced by surgical trauma.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Behav Neurosci. 2023 ;17:1162009. Epub 2023 Jun 7. PMID:
37351155
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Icariin
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Postoperative Recovery
Pharmacological Actions
:
Neuroprotective Agents
[+]
Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1227145. Epub 2023 Aug 24. PMID:
37693917
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Oxidative Stress
,
Prenatal Chemical Exposures
Additional Keywords
:
Increased Risk
Problem Substances
:
Electronic Cigarettes
[+]
Inhibitory effects of walnut peptides on neuroinflammation and oxidative stress in lipopolysaccharide-induced cognitive impairment.
Feb 25, 2020
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2020 Feb 26 ;68(8):2381-2392. Epub 2020 Feb 18. PMID:
32037817
Article Published Date
: Feb 25, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Walnut
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ipriflavone and Ipriflavone loaded albumin nanoparticles reverse lipopolysaccharide induced neuroinflammation.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2020 ;15(8):e0237929. Epub 2020 Aug 21. PMID:
32822403
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ipriflavone
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
[+]
Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity.
Jan 05, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Neurosci. 2019 08 6 ;20(1):41. Epub 2019 Aug 6. PMID:
31387531
Article Published Date
: Jan 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Isoliquiritigenin pre-treatment plays neuroprotective and anti-inflammatory roles in kainic acid-induced epileptogenesis.
Apr 28, 2019
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2019 Apr 29. Epub 2019 Apr 29. PMID:
31037573
Article Published Date
: Apr 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Brain Inflammation
,
Epilepsy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Isorhamnetin attenuates high-fat and high-fructose diet induced cognitive impairments and neuroinflammation.
Oct 03, 2021
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2021 Oct 4 ;12(19):9261-9272. Epub 2021 Oct 4. PMID:
34606526
Article Published Date
: Oct 03, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
