Brain Injury: Traumatic

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55 Substances Researched for Brain Injury: Traumatic
NameACCKFocus
Melatonin526Locked
Curcumin814Locked
Hydrogen Water612Locked
Delta-tetrahydrocannabinol (THC)110Locked
Vitamin D110Locked
Ashwagandha26Locked
Astaxanthin36Locked
Formononetin36Locked
Isoliquiritigenin36Locked
Sulforaphane24Locked
Tanshinone IIA24Locked
Cannabidiol23Locked
Flavonoids23Locked
Pycnogenol (Pine Bark)23Locked
Safflower23Locked
Aloe Vera12Locked
Apocynin12Locked
Berberine12Locked
Beta-Elemene12Locked
Blueberry12Locked
Caffeic acid phenethyl ester12Locked
Carnosic Acid12Locked
Ferulic acid12Locked
Fisetin12Locked
Folate12Locked
Folic Acid 12Locked
Fucoxanthin 12Locked
Hesperidin12Locked
Honokiol12Locked
Huperzine12Locked
Ligustrazine12Locked
Mangiferin12Locked
NAC (N-acetyl-L-cysteine)12Locked
Omega-3 Fatty Acids12Locked
Onion12Locked
Paeoniflorin12Locked
Palmitoylethanolamide 12Locked
Panax Notoginseng12Locked
Psychedelics:All 12Locked
Quercetin12Locked
Resveratrol22Locked
Sinomenine12Locked
Taurine12Locked
Thiamine (B-1) 12Locked
Ubiquinol12Locked
Wogonin12Locked
Alpha-Lipoic Acid11Locked
Antioxidant formulas11Locked
Cannabinoids 11Locked
Curcuminoids11Locked
Ginsenosides11Locked
Persimmon 11Locked
Rhubarb11Locked
Tetrahydrocurcumin11Locked
beta-Carotene11Locked
2 Problem Substances Researched for Brain Injury: Traumatic
NameACCKFocus
Aspirin 110Locked
Clopidogrel110Locked
10 Therapeutic Actions Researched for Brain Injury: Traumatic
NameACCKFocus
Music441Locked
Acupressure110Locked
Qigong110Locked
Tai Chi110Locked
Yoga110Locked
Dietary Modification: Low Carbohydrate/Ketogenic24Locked
Hyperbaric Treatment24Locked
Light-Emitting Diodes (LEDs) Therapy13Locked
Laser Treatment 12Locked
Laser Treatment: Low-Level12Locked

View the Evidence:
108 Abstracts with Brain Injury: Traumatic Research

[+]

The role of music therapy in traumatic brain injury.Oct 28, 2020

Pubmed Data : World Neurosurg. 2020 Oct 29. Epub 2020 Oct 29. PMID: 33130286
Article Published Date : Oct 28, 2020
Study Type : Meta Analysis, Review
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Music
[+]

There is evidence that melatonin treatment after traumatic brain injury significantly improves both behavioural outcomes and pathological outcomes.Jun 13, 2018

Pubmed Data : J Neurotrauma. 2018 Jun 14. Epub 2018 Jun 14. PMID: 29901413
Article Published Date : Jun 13, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

A positive THC screen is associated with decreased mortality in adult patients sustaining traumatic brain injury.Sep 30, 2014

Pubmed Data : Am Surg. 2014 Oct ;80(10):979-83. PMID: 25264643
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Substances : Delta-tetrahydrocannabinol (THC)
Diseases : Brain Injury: Traumatic
Additional Keywords : Mortality, Significant Treatment Outcome
[+]

A Qigong exercise intervention programme may improve mood and self-esteem for individuals with traumatic brain injury. Jul 01, 2009

Pubmed Data : Clin Rehabil. 2009 Jul;23(7):589-98. Epub 2009 Feb 23. PMID: 19237436
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Qigong, Tai Chi
[+]

Acupressure appears to improve memory as a non-pharmacological intervention for traumatic brain injury.Oct 27, 2010

Pubmed Data : J Neurotrauma. 2010 Oct 27. Epub 2010 Oct 27. PMID: 20979460
Article Published Date : Oct 27, 2010
Study Type : Human Study
Additional Links
Diseases : Brain Injury: Traumatic, Memory Loss
Therapeutic Actions : Acupressure
[+]

Neurologic music therapy improves executive function and emotional adjustment in traumatic brain injury rehabilitation.Jul 01, 2009

Pubmed Data : Ann N Y Acad Sci. 2009 Jul;1169:406-16. PMID: 19673815
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Music
[+]

The effect of music therapy on physiological parameters of patients with traumatic brain injury.Jul 31, 2020

Pubmed Data : Complement Ther Clin Pract. 2020 Aug ;40:101216. Epub 2020 Jun 30. PMID: 32891292
Article Published Date : Jul 31, 2020
Study Type : Human Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Music
[+]

There is high mortality rate associated with aspirin or clopidogrel or both in elderly patients who have head trauma resulting in intracranial hemmorhage. Oct 01, 2008

Pubmed Data : J Trauma. 2008 Oct;65(4):785-8. PMID: 18849791
Article Published Date : Oct 01, 2008
Study Type : Human Study
Additional Links
Diseases : Brain Injury: Traumatic, Intracranial Hemmorhage
Problem Substances : Aspirin , Clopidogrel
[+]

Vitamin D deficiency is common in patients after TBI and associated with impaired cognitive function and more severe depressive symptoms.Feb 26, 2016

Pubmed Data : Clin Endocrinol (Oxf). 2016 Feb 27. Epub 2016 Feb 27. PMID: 26921561
Article Published Date : Feb 26, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Brain Injury: Traumatic, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Yoga led to significant improvements in balance, mobility, and self-reported occupational performance in adults with chronic brain injury.Apr 07, 2020

Pubmed Data : Complement Ther Clin Pract. 2020 Apr 8 ;40:101172. Epub 2020 Apr 8. PMID: 32347208
Article Published Date : Apr 07, 2020
Study Type : Human Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Yoga
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

W. somnifera root extract was neuroprotective and could have therapeutic potential in secondary injury and long-term sequelae of mild TBI.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Transplant. 2017 Jul ;26(7):1193-1201. PMID: 28933215
Article Published Date : Jun 30, 2017
Study Type : Human In Vitro
Additional Links
Substances : Ashwagandha
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Two cases of improved cognitive function After transcranial, light-emitting diode treatments in chronic, traumatic brain injury.Dec 23, 2010

Pubmed Data : Photomed Laser Surg. 2010 Dec 23. Epub 2010 Dec 23. PMID: 21182447
Article Published Date : Dec 23, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Role of CAPE in reducing oxidative stress in animal models with traumatic brain injury Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Med Surg (Lond). 2020 Sep ;57:118-122. Epub 2020 Jul 22. PMID: 32760580
Article Published Date : Aug 31, 2020
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

6-Shogaol treatment produced beneficial effects for TBI-induced anxiety/depression-like behaviors.Jan 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Omega. 2022 Jan 11 ;7(1):140-148. Epub 2021 Dec 28. PMID: 35036685
Article Published Date : Jan 10, 2022
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol
Diseases : Brain Injury: Traumatic, Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A curcumin derivative restores membrane homeostasis disrupted after brain trauma.Nov 01, 2010

Pubmed Data : Exp Neurol. 2010 Nov;226(1):191-9. Epub 2010 Sep 15. PMID: 20816821
Article Published Date : Nov 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Damage, Brain Injury: Traumatic, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents, Neurorestorative
[+]

A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2021 ;11(1):346-360. Epub 2021 Jan 1. PMID: 33391479
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Neuroprotective Agents
[+]

Administering ubiquinol 30 min before traumatic brain injury significantly affected cerebral gene expression profiles.Jun 30, 2017

Pubmed Data : Nurs Outlook. 2017 Jul 1. Epub 2017 Jul 1. PMID: 28755974
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Gene Expression Regulation
[+]

Administration of palmitoylethanolamide protects the neurovascular unit and reduces secondary injury after traumatic brain injury.Oct 31, 2012

Pubmed Data : Brain Behav Immun. 2012 Nov ;26(8):1310-21. Epub 2012 Aug 3. PMID: 22884901
Article Published Date : Oct 31, 2012
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Aloin protects against blood-brain barrier damage after traumatic brain injury in mice.May 31, 2020

Pubmed Data : Neurosci Bull. 2020 Jun ;36(6):625-638. Epub 2020 Feb 25. PMID: 32100248
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Andrographolide alleviates acute brain injury. Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2018 ;12:657. Epub 2018 Sep 20. PMID: 30294256
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Andrographolide
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Apocynin has a protective role in a rat model of traumatic brain injury.Aug 06, 2017

Pubmed Data : Neurochem Res. 2017 Aug 7. Epub 2017 Aug 7. PMID: 28786047
Article Published Date : Aug 06, 2017
Study Type : Animal Study
Additional Links
Substances : Apocynin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astaxanthin improves cognitive performance in mice following mild traumatic brain injury.Dec 30, 2016

Pubmed Data : Brain Res. 2016 Dec 31. Epub 2016 Dec 31. PMID: 28048972
Article Published Date : Dec 30, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Astaxanthin provides neuroprotection in an experimental model of traumatic brain injury.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2021 ;13(3):1483-1493. Epub 2021 Mar 15. PMID: 33841672
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Astaxanthin reduces traumatic brain injury-related injury in brain tissue.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Neurosci. 2016 ;17(1):60. Epub 2016 Aug 31. PMID: 27581370
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Berberine protects secondary injury in mice with traumatic brain injury. Jul 18, 2018

Pubmed Data : Neurochem Res. 2018 Jul 19. Epub 2018 Jul 19. PMID: 30027364
Article Published Date : Jul 18, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Bone mesenchymal stem cell exosomes exert a neuroprotective effect by inhibiting early neuroinflammation.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2019 ;13:14. Epub 2019 Jan 24. PMID: 30733666
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Exosomes, Mesenchymal Stem Cells
[+]

Carnosic acid improves outcome after repetitive mild traumatic brain injury.Jun 30, 2019

Pubmed Data : J Neurotrauma. 2019 Jul 1 ;36(13):2147-2152. Epub 2019 Mar 26. PMID: 30672378
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Curcumin attenuates cerebral edema following traumatic brain injury in mice.Feb 01, 2010

Pubmed Data : J Neurochem. 2010 Feb 1. Epub 2010 Feb 1. PMID: 20132469
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin has a neuroprotective effect in brain trauma. Jul 21, 2009

Pubmed Data : Neuroscience. 2009 Jul 21;161(4):1037-44. Epub 2009 Apr 21. PMID: 19393301
Article Published Date : Jul 21, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin treatment significantly improved the neurological status evaluated during 2 weeks after brain injury.Aug 31, 2013

Pubmed Data : Pharmacol Biochem Behav. 2013 Sep ;110:238-44. Epub 2013 Aug 7. PMID: 23932920
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Brain Injury: Traumatic, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury.Jan 09, 2020

Pubmed Data : J Control Release. 2020 07 10 ;323:361-375. Epub 2020 Apr 24. PMID: 32339548
Article Published Date : Jan 09, 2020
Study Type : Animal Study
Additional Links
Substances : Sinomenine
Diseases : Brain Inflammation , Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary blueberry supplementation has a beneficial effect in mitigating the acute aspects of the traumatic brain injury pathology.May 20, 2019

Pubmed Data : Mol Nutr Food Res. 2019 May 21:e1801055. Epub 2019 May 21. PMID: 31115168
Article Published Date : May 20, 2019
Study Type : Animal Study
Additional Links
Substances : Blueberry
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition.Feb 01, 2006

Pubmed Data : Exp Neurol. 2006 Feb;197(2):309-17. Epub 2005 Dec 20. PMID: 16364299
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Injury: Traumatic, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
[+]

Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury.Mar 31, 2018

Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Apr ;30(4):317-321. PMID: 29663991
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Expression of VEGF and GFAP in a rat model of traumatic brain injury treated with honokiol.Mar 04, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Folia Morphol (Warsz). 2019 Mar 5. Epub 2019 Mar 5. PMID: 30835336
Article Published Date : Mar 04, 2019
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Fisetin alleviates oxidative stress after traumatic brain injury.May 21, 2018

Pubmed Data : Neurochem Int. 2018 May 22. Epub 2018 May 22. PMID: 29792955
Article Published Date : May 21, 2018
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.Apr 30, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Invest. 2010 May ;120(5):1603-16. Epub 2010 Apr 26. PMID: 20424322
Article Published Date : Apr 30, 2010
Study Type : Animal Study
Additional Links
Substances : Folate, Folic Acid
Diseases : Brain Injury: Traumatic, Spinal Cord Injuries
Pharmacological Actions : Regenerative
Additional Keywords : DNA Methylation, Nerve Regeneration
[+]

Formononetin mediates the promising anti-traumatic brain injury effects against neurocyte damage.Mar 14, 2014

Pubmed Data : J Neurol Sci. 2014 Mar 15 ;338(1-2):112-7. Epub 2013 Dec 27. PMID: 24411660
Article Published Date : Mar 14, 2014
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoxanthin provides neuroprotection in models of traumatic brain injury.Apr 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Apr 21 ;7:46763. Epub 2017 Apr 21. PMID: 28429775
Article Published Date : Apr 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
Additional Keywords : Antioxidants, Brain Injury: Traumatic, Fucoxanthin, Neuroprotective Agents, Nrf2 activation
[+]

Harmine may exert neuroprotective effects by synergistically reducing excitotoxicity and inflammation following traumatic brain injury.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2015 Dec ;12(6):7985-91. Epub 2015 Oct 13. PMID: 26496827
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Psychedelics:All
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hericium erinaceus and Coriolus versicolor modulate molecular and biochemical changes after traumatic brain injury.Jun 01, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Jun 2 ;10(6). Epub 2021 Jun 2. PMID: 34199629
Article Published Date : Jun 01, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Turkey Tail Mushroom
Diseases : Brain Injury: Traumatic, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Hesperidin attenuates depression-related symptoms in mice with mild traumatic brain injury.Nov 14, 2018

Pubmed Data : Life Sci. 2018 Nov 15 ;213:198-205. Epub 2018 Oct 21. PMID: 30352242
Article Published Date : Nov 14, 2018
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Hesperidin
Diseases : Brain Inflammation , Brain Injury: Traumatic, Depression, Oxidative Stress
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.Jan 11, 2017

Pubmed Data : Metab Brain Dis. 2017 12 ;32(6):1861-1869. Epub 2017 Jul 26. PMID: 28748496
Article Published Date : Jan 11, 2017
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Brain Inflammation , Brain Injury: Traumatic, Learning disorders, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Hydrogen rich water could exert a neuroprotective effect against traumatic brain injury and attenuate inflammation.Apr 14, 2016

Pubmed Data : Brain Res. 2016 Apr 15 ;1637:1-13. Epub 2016 Jan 26. PMID: 26826009
Article Published Date : Apr 14, 2016
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain Inflammation , Brain Injury: Traumatic, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-10 downregulation, Neuroprotective Agents
[+]

Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.Jul 31, 2018

Pubmed Data : J Surg Res. 2018 Aug ;228:238-246. Epub 2018 Apr 11. PMID: 29907217
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Hydrogen-rich water has beneficial effects on the expression of aquaporin 1 in the cerebral cortex of rat with traumatic brain injury.Apr 30, 2016

Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2016 May ;28(5):460-4. PMID: 29923387
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Hydrogen-rich water promote CD34+ cells home to the site of injured tissue in rats with traumatic brain injury.Feb 28, 2017

Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2017 Mar ;29(3):260-264. PMID: 28627348
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Immunomodulatory, Neuroprotective Agents
[+]

Hydroxysafflor yellow A exerts antioxidant effects in a rat model of traumatic brain injury.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2016 Oct ;14(4):3690-6. Epub 2016 Sep 6. PMID: 27599591
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Brain: Oxidative Stress, Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Increased miR-155 and heme oxygenase-1 expression is involved in the protective effects of formononetin in traumatic brain injury.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2017 ;9(12):5653-5661. Epub 2017 Dec 15. PMID: 29312517
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, MicroRNA modulator, Neuroprotective Agents
[+]

Integrated metabolomics and network pharmacology to reveal the mechanisms of hydroxysafflor yellow A against acute traumatic brain injury.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Comput Struct Biotechnol J. 2021 ;19:1002-1013. Epub 2021 Jan 26. PMID: 33613866
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Isoliquiritigenin attenuates neuroinflammation in traumatic brain injury.Dec 31, 2018

Pubmed Data : Neuroimmunomodulation. 2019 ;26(2):102-110. Epub 2019 Feb 15. PMID: 30783039
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Neuroprotective Agents
[+]

Isoliquiritigenin protects against blood brain barrier damage and inhibits the secretion of pro-inflammatory cytokines in mice after traumatic brain injury.Nov 30, 2018

Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:64-75. Epub 2018 Oct 2. PMID: 30290368
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Isoliquiritigenin provides protection and attenuates oxidative stress-induced injuries after traumatic brain injury.Nov 30, 2018

Pubmed Data : Neurochem Res. 2018 Dec ;43(12):2435-2445. Epub 2018 Nov 16. PMID: 30446968
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Brain Injury: Traumatic, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Ketogenic Diet as a potential treatment for traumatic brain injury in mice.Dec 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Dec 7 ;11(1):23559. Epub 2021 Dec 7. PMID: 34876621
Article Published Date : Dec 06, 2021
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Neuroprotective Agents
[+]

Ketogenic diet protects myelin and axons in diffuse axonal injury.Jan 22, 2021

Pubmed Data : Nutr Neurosci. 2021 Jan 23:1-14. Epub 2021 Jan 23. PMID: 33487123
Article Published Date : Jan 22, 2021
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Neuroprotective Agents
[+]

Low-level Laser therapy applied transcranially to mice following traumatic brain injury significantly reduces long-term neurological deficits.Apr 01, 2007

Pubmed Data : J Neurotrauma. 2007 Apr;24(4):651-6. PMID: 17439348
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Laser Treatment , Laser Treatment: Low-Level
Pharmacological Actions : Neurorestorative
[+]

Mangiferin attenuates blast-induced traumatic brain injuryApr 24, 2017

Pubmed Data : Chem Biol Interact. 2017 Apr 25 ;271:15-23. Epub 2017 Apr 25. PMID: 28455230
Article Published Date : Apr 24, 2017
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Melatonin restores KCC2 expression, inhibits neuronal apoptosis and attenuates secondary brain injury after traumatic brain injury.May 08, 2016

Pubmed Data : J Pineal Res. 2016 May 9. Epub 2016 May 9. PMID: 27159133
Article Published Date : May 08, 2016
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Melatonin supplementation has protective effect on oxidative stress and antioxidant redox system in the cerebral cortex and blood.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2014 Jun 1 ;9(11):1112-6. PMID: 25206769
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain: Oxidative Stress, Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(9):e108034. Epub 2014 Sep 24. PMID: 25251220
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Alzheimer's Disease, Brain Injury: Traumatic, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Risk Reduction
[+]

N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2018 ;12:4117-4127. Epub 2018 Dec 4. PMID: 30584276
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Brain: Oxidative Stress, Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Neuroprotective effect of formononetin against traumatic brain injury.Sep 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Oct ;106:349-354. Epub 2018 Jul 11. PMID: 29966980
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Omega-3 polyunsaturated fatty acids supplementation attenuates the inflammatory response by modulating microglial polarization.Apr 19, 2018

Pubmed Data : J Neuroinflammation. 2018 Apr 20 ;15(1):116. Epub 2018 Apr 20. PMID: 29678169
Article Published Date : Apr 19, 2018
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Brain Injury: Traumatic, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Onion exhibits a neuroprotective effect on cerebral ischemia and injury. Feb 01, 2008

Pubmed Data : Fitoterapia. 2008 Feb;79(2):86-96. Epub 2007 Aug 11. PMID: 17900821
Article Published Date : Feb 01, 2008
Study Type : Animal Study
Additional Links
Substances : Onion
Diseases : Brain Injury: Traumatic, Cerebral Ischemia, Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Oral cannabidiol prevents allodynia and neurological dysfunctions in a mouse model of mild traumatic brain injury.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:352. Epub 2019 Apr 16. PMID: 31040777
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Allodynia, Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Paeoniflorin supplementation has potent protective efficiency against neonatal hypoxia/ischemia-induced brain injury.Feb 28, 2021

Pubmed Data : Korean J Physiol Pharmacol. 2021 Mar 1 ;25(2):97-109. PMID: 33602880
Article Published Date : Feb 28, 2021
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Brain: Oxidative Stress, Brain Hypoxia, Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Panax notoginseng protects the rat brain function from traumatic brain injury.Apr 03, 2021

Pubmed Data : Aging (Albany NY). 2021 Apr 4 ;13. Epub 2021 Apr 4. PMID: 33819197
Article Published Date : Apr 03, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Autophagy Inhibitors, Neuroprotective Agents
[+]

Post-injury curcumin administration may improve patient outcome by reducing acute activation of microglia/macrophages and neuronal apoptosis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2014 ;11:59. Epub 2014 Mar 27. PMID: 24669820
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Pycnogenol preserves synaptic function after controlled cortical impact injury.Jan 31, 2016

Pubmed Data : Exp Neurol. 2016 Feb ;276:5-12. Epub 2015 Nov 29. PMID: 26607913
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Quercetin improves mitochondrial function in traumatic brain injury models.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(10):e0164237. Epub 2016 Aug 25. PMID: 27780244
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Saffron extract and crocin exert anti-inflammatory and anti-oxidative effects in a repetitive mild traumatic brain injury mouse model.Jan 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2022 03 23 ;12(1):5004. Epub 2022 Mar 23. PMID: 35322143
Article Published Date : Jan 22, 2022
Study Type : Animal Study
Additional Links
Substances : Crocin, Saffron
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Sinomenine reduces neuronal cell apoptosis in mice after traumatic brain injury.Dec 31, 2017

Pubmed Data : Drug Des Devel Ther. 2018 ;12:77-84. Epub 2018 Jan 5. PMID: 29379271
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Sinomenine
Diseases : Brain: Oxidative Stress, Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Sulforaphane improves cognitive function administered following traumatic brain injury.Aug 28, 2009

Pubmed Data : Neurosci Lett. 2009 Aug 28;460(2):103-7. Epub 2009 Apr 15. PMID: 19515491
Article Published Date : Aug 28, 2009
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Blood-Brain-Barrier Disorders, Brain Damage, Brain Injury: Traumatic, Cognitive Decline/Dysfunction
Pharmacological Actions : Anticarcinogenic Agents, Neuroprotective Agents
[+]

Sulforphane attenuates oxidative stress and neuronal damage following traumatic brain injury. Oct 18, 2010

Pubmed Data : Acta Pharmacol Sin. 2010 Oct 18. Epub 2010 Oct 18. PMID: 20953205
Article Published Date : Oct 18, 2010
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Brain Injury: Traumatic, Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Tanshinone IIA attenuates neuronal loss in mouse traumatic brain injury model.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2020 ;16:3239-3250. Epub 2020 Dec 31. PMID: 33408474
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Taurine may alleviate edema and elevation in intracranial pressure.May 06, 2016

Pubmed Data : Amino Acids. 2016 May 7. Epub 2016 May 7. PMID: 27156064
Article Published Date : May 06, 2016
Study Type : Animal Study
Additional Links
Substances : Taurine
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Tetramethylpyrazine attenuates periorbital allodynia and neuroinflammation in a model of traumatic brain injury.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inflamm (Lond). 2017 ;14:13. Epub 2017 Jun 8. PMID: 28603455
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Allodynia, Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

The attenuation of traumatic brain injury via inhibition of oxidative stress and apoptosis by Tanshinone IIA.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:4170156. Epub 2020 May 1. PMID: 32454938
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

The effect of ferulic acid on experimental traumatic brain damage in rats.Dec 31, 2018

Pubmed Data : Bratisl Lek Listy. 2019 ;120(5):372-379. PMID: 31113201
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

The present study concludes the neuroprotective effect of β-elemene against traumatic brain injury and synergistic effect with hyperbaric oxygen.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Neurosci. 2018 ;9:33-37. Epub 2018 Jun 30. PMID: 29992051
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Beta-Elemene
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Neuroprotective Agents
[+]

The protection effect and mechanism of hyperbaric oxygen therapy in rat brain with traumatic injury.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Cir Bras. 2018 Apr ;33(4):341-353. PMID: 29768537
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Apoptotic
[+]

These data demonstrated that ECFC-derived exosomes have beneficial effects on blood-brain barrier integrity in mice with traumatic brain injury.Jun 05, 2018

Pubmed Data : Exp Neurol. 2018 Jun 6 ;307:99-108. Epub 2018 Jun 6. PMID: 29883579
Article Published Date : Jun 05, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Additional Keywords : Blood Brain Barrier, Exosomes
[+]

These findings provide significant clinical potentials to improve the quality of life for TBI patients. Jun 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2021 Jun 15 ;18(1):137. Epub 2021 Jun 15. PMID: 34130727
Article Published Date : Jun 14, 2021
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Thiamine preserves mitochondrial function in a rat model of traumatic brain injury.May 15, 2018

Pubmed Data : Biochim Biophys Acta. 2018 May 16. Epub 2018 May 16. PMID: 29777685
Article Published Date : May 15, 2018
Study Type : Animal Study
Additional Links
Substances : Thiamine (B-1)
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Wogonin attenuates the deleterious effects of traumatic brain injury.Apr 04, 2019

Pubmed Data : Eur J Pharmacol. 2019 Apr 5 ;848:121-130. Epub 2019 Jan 25. PMID: 30689996
Article Published Date : Apr 04, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Alantolactone plays neuroprotective roles in traumatic brain injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2018 ;10(2):368-380. Epub 2018 Feb 15. PMID: 29511431
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Elecampane
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Antioxidant therapies for traumatic brain injury.Jan 01, 2010

Pubmed Data : Neurotherapeutics. 2010 Jan;7(1):51-61. PMID: 20129497
Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Substances : Alpha-Lipoic Acid, Antioxidant formulas, Curcumin, Resveratrol
Diseases : Brain Injury: Traumatic, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Antioxidative effects of Panax notoginseng saponin in brain cells.Sep 14, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2014 Sep 15 ;21(10):1189-95. Epub 2014 Jun 7. PMID: 24916704
Article Published Date : Sep 14, 2014
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Alzheimer's Disease, Brain Injury: Traumatic, Oxidative Stress, Stroke: Attenuation/Recovery
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Cannabidiol and other cannabinoids in demyelinating diseases. Mar 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Mar 15 ;22(6). Epub 2021 Mar 15. PMID: 33804243
Article Published Date : Mar 14, 2021
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabinoids
Diseases : Brain Injury: Traumatic, Multiple Sclerosis, Stroke
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Demyelinating Diseases
[+]

Curcuminoids prevent experimentally induced neuronal damage in the rat hippocampus.Mar 13, 2006

Pubmed Data : Life Sci. 2006 Mar 13;78(16):1884-91. Epub 2005 Nov 2. PMID: 16266725
Article Published Date : Mar 13, 2006
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Curcuminoids
Diseases : Brain Injury: Hippocampal Damage, Brain Injury: Traumatic, Epilepsy, Oxidative Stress, Seizures, Stroke
Pharmacological Actions : Apoptotic, Excitatory Amino Acid Agonists, Neuroprotective Agents
[+]

Dual effects of Korean Red Ginseng on astrocytes and neural stem cells in traumatic brain injury.Mar 03, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2022 Mar 4 ;11(5). Epub 2022 Mar 4. PMID: 35269514
Article Published Date : Mar 03, 2022
Study Type : In Vitro Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents
[+]

Exosomes from MiR-21-5p-increased neurons play a role in neuroprotection.Mar 11, 2019

Pubmed Data : Med Sci Monit. 2019 Mar 12 ;25:1871-1885. Epub 2019 Mar 12. PMID: 30860987
Article Published Date : Mar 11, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Exosomes
[+]

Flavonoids from persimmon leaves may have a therapeutic role in preventing and treating brain injuries and/or inflammation. May 01, 2009

Pubmed Data : Zhong Yao Cai. 2009 May;32(5):740-4. PMID: 19771850
Article Published Date : May 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Persimmon
Diseases : Brain Inflammation , Brain Injury: Traumatic, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Melatonin has protective effects against acute IL-1β-induced blood brain barrier dysfunction and hyperpermeability.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(5):e0154427. Epub 2016 May 6. PMID: 27152411
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Brain Edema, Brain Injury: Traumatic
Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Blood Brain Barrier
[+]

Music may facilitate neurogenesis, regeneration and repair of neurons.Nov 01, 2008

Pubmed Data : Med Hypotheses. 2008 Nov;71(5):765-9. Epub 2008 Aug 8. PMID: 18692321
Article Published Date : Nov 01, 2008
Study Type : Commentary
Additional Links
Diseases : Brain Injury: Traumatic, Cortisol: Low, Estrogen Deficiency, Testosterone: Too Low
Therapeutic Actions : Music
Pharmacological Actions : Neuritogenic, Secretagogue
[+]

Neuroprotective effects of anthraquinones from rhubarb in central nervous system diseases.Dec 31, 2018

Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:3790728. Epub 2019 May 16. PMID: 31223328
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Rhubarb
Diseases : Alzheimer's Disease, Brain Injury: Traumatic, Depression, Intracerebral Hemorrhage, Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective potential of caffeic acid phenethyl ester in CNS disorders.Jun 07, 2021

Pubmed Data : Curr Neuropharmacol. 2021 Jun 8. Epub 2021 Jun 8. PMID: 34102977
Article Published Date : Jun 07, 2021
Study Type : Review
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Anxiety, Brain Injury: Traumatic, Depression, Epilepsy, Huntington Disease, Parkinson's Disease, Stroke
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Protective effects of curcumin against traumatic brain injury.Sep 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Oct ;154:113621. Epub 2022 Aug 30. PMID: 36055110
Article Published Date : Sep 30, 2022
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Pycnogenol has neuroprotective effects in traumatic brain injury.Oct 07, 2012

Pubmed Data : Exp Neurol. 2012 Oct 8 ;239C:183-191. Epub 2012 Oct 8. PMID: 23059456
Article Published Date : Oct 07, 2012
Study Type : Review
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Resveratrol has neuroprotective properties. Jan 01, 2011

Pubmed Data : Neurochem Res. 2011 Jan;36(1):17-26. Epub 2010 Sep 15. PMID: 20842424
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Tetrahydrocurcumin may be an effective therapeutic agent to treat traumatic brain injury.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2017 ;9(3):887-899. Epub 2017 Mar 15. PMID: 28386319
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

The collective findings strongly suggest that melatonin may regulate TBI-induced neurodegeneration.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inflamm Res. 2021 ;14:6251-6264. Epub 2021 Nov 27. PMID: 34866924
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Brain Injury: Traumatic, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

The gut-brain axis may be a therapeutic target to reduce the risk of Chronic Traumatic Encephalopathy and other neurodegenerative diseases following TBI.May 16, 2017

Pubmed Data : Brain Behav Immun. 2017 May 17. Epub 2017 May 17. PMID: 28526435
Article Published Date : May 16, 2017
Study Type : Review
Additional Links
Diseases : Brain Injury: Traumatic
Additional Keywords : Gut-brain Axis, Microbiota
[+]

Therapeutic potential of hydroxysafflor yellow A on cardio-cerebrovascular diseases.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:01265. Epub 2020 Sep 29. PMID: 33117148
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Safflower
Diseases : Atherosclerosis, Brain Injury: Traumatic, Cerebral Ischemia, Cerebrovascular Disorders, Dementia, Myocardial Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

This indicates that W. somnifera root extract was neuroprotective and could have therapeutic potential in mild traumatic brain injury.Jan 17, 2016

Pubmed Data : Cell Transplant. 2016 11 18. Epub 2016 Nov 18. PMID: 27938496
Article Published Date : Jan 17, 2016
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Treatment with melatonin significantly ameliorated neuronal death and behavioral deficits after traumatic brain injury.Apr 26, 2016

Pubmed Data : J Pineal Res. 2016 Apr 27. Epub 2016 Apr 27. PMID: 27117839
Article Published Date : Apr 26, 2016
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Brain Inflammation , Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

β-carotene provides neuro protection after experimental traumatic brain injury via the Nrf2-ARE pathway.Jun 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Integr Neurosci. 2019 Jun 30 ;18(2):153-161. PMID: 31321956
Article Published Date : Jun 29, 2019
Study Type : In Vitro Study
Additional Links
Substances : beta-Carotene
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Progesterone attenuates adverse neurologic and morphologic changes following traumatic brain injury in rats.May 01, 2007

Pubmed Data : Exp Neurol. 2007 May;205(1):145-53. Epub 2007 Feb 12. PMID: 17362936
Article Published Date : May 01, 2007
Additional Links
Diseases : Brain Injury: Traumatic

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