Breast Cancer: Drug Resistant

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11 Substances Researched for Breast Cancer: Drug Resistant

Name	AC	CK
Amurensin G	2	10
Bloodroot	1	1
Chia	1	1
Curcumin	1	1
Medicinal Mushrooms	1	1
Progesterone	1	1
Quercetin	1	1
Reishi Mushroom	1	1
Resveratrol	1	1
Shikonin	1	1
Vitamin E: Gamma-tocotrienol	1	1

3 Problem Substances Researched for Breast Cancer: Drug Resistant

Name	AC	CK
Doxorubicin	1	5
Morphine	1	1
Tamoxifen	1	1

Research Articles 14
Cumulative Knowledge Score 22
Overall Research Rating GOOD

View the Evidence:
14 Abstracts with Breast Cancer: Drug Resistant Research

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[+]

Amurensin G had significant antiangiogenic and antitumor growth effects in tamoxifen resistant breast cancer.Sep 30, 2012

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2012 Oct ;50(10):3625-34. Epub 2012 Jul 27. PMID: 22842120

Article Published Date : Sep 30, 2012

Study Type : Human In Vitro

Additional Links

Substances : Amurensin G

Diseases : Breast Cancer, Breast Cancer: Drug Resistant

Pharmacological Actions : Anti-Angiogenic, Anti-Tumor, Antineoplastic Agents, Hypoxia-inducible factor-1 (HIF-1) inhibitor, Vascular Endothelial Growth Factor A Inhibitor

Additional Keywords : Epigenetic Modification In Cancer, Gene Expression Regulation

[+]

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Pharmacol. 2010 Nov ;78(5):855-64. Epub 2010 Aug 16. PMID: 20713551

Article Published Date : Oct 31, 2010

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Amurensin G

Diseases : Breast Cancer: Drug Resistant, Cancers: Drug Resistant

Pharmacological Actions : Chemosensitizer

Additional Keywords : Gene Expression Regulation, Natural Substance/Drug Synergy, Plant Extracts

Problem Substances : Doxorubicin

[+]

"Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9."Dec 31, 2012

Click here to read the entire abstract

Pubmed Data : Molecules. 2013 ;18(1):701-20. Epub 2013 Jan 8. PMID: 23299550

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Breast Cancer: Drug Resistant

Pharmacological Actions : Chemosensitizer

Additional Keywords : Tamoxifen Resistance

[+]

"Insights into the cell of origin in breast cancer and breast cancer stem cells."May 31, 2010

Click here to read the entire abstract

Pubmed Data : Asia Pac J Clin Oncol. 2010 Jun ;6(2):89-97. PMID: 20565420

Article Published Date : May 31, 2010

Study Type : Review

Additional Links

Diseases : Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer Stem Cells, Cancer Stem Cells

Additional Keywords : Cancer Hypotheses, Cancer Stem Cells

[+]

"Progesterone Receptor Down-Regulates BCRP Expression via Binding to the Progesterone Response Element in Breast Cancer."Feb 20, 2012

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Pubmed Data : Cancer Sci. 2012 Feb 20. Epub 2012 Feb 20. PMID: 22348324

Article Published Date : Feb 20, 2012

Study Type : In Vitro Study

Additional Links

Substances : Progesterone

Diseases : Breast Cancer: Drug Resistant, Cancers: Drug Resistant

Pharmacological Actions : Breast cancer resistance protein (BCRP) down-regulation

[+]

Antrodia cinnamomea extract inhibits the proliferation of tamoxifen-resistant breast cancer cells.May 08, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2018 May 9 ;18(1):152. Epub 2018 May 9. PMID: 29743060

Article Published Date : May 08, 2018

Study Type : In Vitro Study

Additional Links

Substances : Medicinal Mushrooms

Diseases : Breast Cancer, Breast Cancer: Drug Resistant

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Gamma-tocotrienol reverses multidrug resistance of breast cancer cells.Nov 14, 2016

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Pubmed Data : J Steroid Biochem Mol Biol. 2016 Nov 15. Epub 2016 Nov 15. PMID: 27864002

Article Published Date : Nov 14, 2016

Study Type : In Vitro Study

Additional Links

Substances : Vitamin E: Gamma-tocotrienol

Diseases : Breast Cancer: Drug Resistant

Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemosensitizer, Multidrug Resistance Gene Modulators

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Ganoderenic acid B has the potential to be developed into an ABCB1-mediated multidrug resistance reversal agent.Apr 30, 2015

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Pubmed Data : Int J Oncol. 2015 May ;46(5):2029-38. Epub 2015 Mar 12. PMID: 25779097

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Reishi Mushroom

Diseases : Breast Cancer: Drug Resistant, Cancers: Multi-Drug Resistant, Hepatoma: Multidrug Resistant

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Resistance Reversal

[+]

Oligosaccharides obtained from chia seeds enhanced vinblastine activity. Apr 19, 2017

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Pubmed Data : Phytother Res. 2017 Apr 20. Epub 2017 Apr 20. PMID: 28425219

Article Published Date : Apr 19, 2017

Study Type : In Vitro Study

Additional Links

Substances : Chia

Diseases : Breast Cancer: Drug Resistant

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Natural Substance/Drug Synergy

[+]

Quercetin reversed multidrug resistance in breast cancer cells.Apr 09, 2018

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Pubmed Data : Phytother Res. 2018 Apr 10. Epub 2018 Apr 10. PMID: 29635751

Article Published Date : Apr 09, 2018

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Breast Cancer, Breast Cancer: Drug Resistant

Pharmacological Actions : Chemosensitizer, Multidrug Resistance Gene Modulators

[+]

Resveratrol exhibits anti-cancer properties against tamoxifen-resistant breast cancer cells.Sep 30, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FASEB J. 2011 Oct ;25(10):3695-707. Epub 2011 Jul 7. PMID: 21737614

Article Published Date : Sep 30, 2011

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Breast Cancer: Drug Resistant

Pharmacological Actions : Estrogen Receptor Modulators, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Tamoxifen Resistance

Problem Substances : Tamoxifen

[+]

Sanguinarine as a potent inhibitor of dihydrofolate reductase, able to impair enzyme activity even in methotrexate resistant MDA-MB-231 cells.Jul 31, 2014

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 2014 Aug 1 ;90(3):226-34. Epub 2014 May 27. PMID: 24875448

Article Published Date : Jul 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Bloodroot

Diseases : Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer: Triple Negative

Pharmacological Actions : Antiproliferative , Apoptotic, Cyclin D1 Down-Regulation, Enzyme Inhibitors

Additional Keywords : Bloodroot, Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer: Triple Negative, Dose Response

[+]

Shikonin reduces tamoxifen resistance of MCF-7R breast cancer cells.Oct 23, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Oct 24 ;8(51):88658-88669. Epub 2017 Sep 11. PMID: 29179465

Article Published Date : Oct 23, 2017

Study Type : In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Breast Cancer, Breast Cancer: Drug Resistant

Pharmacological Actions : Chemosensitizer, Chemotherapeutic

[+]

This study found that morphine contributes to chemoresistance via expanding the population of cancer stem cells and promotes tumor growth.Feb 27, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2015 Feb 28 ;6(6):3963-76. PMID: 25686831

Article Published Date : Feb 27, 2015

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer Stem Cells

Additional Keywords : Cancer Stem Cells

Problem Substances : Morphine

Research Articles 14
Cumulative Knowledge Score 22
Overall Research Rating GOOD

Breast Cancer: Drug Resistant Related Articles

Tamoxifen: Praised As "Life Saving" But Still Causing Cancer

Written by Sayer Ji, Founder

Many of the drugs used to treat breast cancer today are probable or known cancer-causing agents. Tamoxifen, for instance, is classified by the World Health Organization as a "human carcinogen," but recent news headlines praised extended use of this drug for "saving lives." It is obvious that the mainstream media has swallowed the tamoxifen-flavored Kool-Aid ... will you?

Flaxseed Helps Prevent And Kill Breast Cancer, Meta-Analysis Reveals

Written by Sayer Ji, Founder

As we edge closer to Breast Cancer Awareness month, a timely new meta-analysis proves that the consumption of flaxseed prevents and kills breast cancer.

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Focus Your Research

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View the Evidence: 14 Abstracts with Breast Cancer: Drug Resistant Research

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Amurensin G had significant antiangiogenic and antitumor growth effects in tamoxifen resistant breast cancer.Sep 30, 2012

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

"Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9."Dec 31, 2012

"Insights into the cell of origin in breast cancer and breast cancer stem cells."May 31, 2010

"Progesterone Receptor Down-Regulates BCRP Expression via Binding to the Progesterone Response Element in Breast Cancer."Feb 20, 2012

Antrodia cinnamomea extract inhibits the proliferation of tamoxifen-resistant breast cancer cells.May 08, 2018

Gamma-tocotrienol reverses multidrug resistance of breast cancer cells.Nov 14, 2016

Ganoderenic acid B has the potential to be developed into an ABCB1-mediated multidrug resistance reversal agent.Apr 30, 2015

Oligosaccharides obtained from chia seeds enhanced vinblastine activity. Apr 19, 2017

Quercetin reversed multidrug resistance in breast cancer cells.Apr 09, 2018

Resveratrol exhibits anti-cancer properties against tamoxifen-resistant breast cancer cells.Sep 30, 2011

Sanguinarine as a potent inhibitor of dihydrofolate reductase, able to impair enzyme activity even in methotrexate resistant MDA-MB-231 cells.Jul 31, 2014

Shikonin reduces tamoxifen resistance of MCF-7R breast cancer cells.Oct 23, 2017

This study found that morphine contributes to chemoresistance via expanding the population of cancer stem cells and promotes tumor growth.Feb 27, 2015

Breast Cancer: Drug Resistant Related Articles

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Breast Cancer: Drug Resistant

View the Evidence:
14 Abstracts with Breast Cancer: Drug Resistant Research