Breast Cancer: Drug Resistant

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11 Substances Researched for Breast Cancer: Drug Resistant
NameACCKFocus
Amurensin G210Locked
Bloodroot11Locked
Chia11Locked
Curcumin11Locked
Medicinal Mushrooms11Locked
Progesterone11Locked
Quercetin11Locked
Reishi Mushroom11Locked
Resveratrol11Locked
Shikonin11Locked
Vitamin E: Gamma-tocotrienol11Locked
3 Problem Substances Researched for Breast Cancer: Drug Resistant
NameACCKFocus
Doxorubicin15Locked
Morphine11Locked
Tamoxifen11Locked

View the Evidence:
14 Abstracts with Breast Cancer: Drug Resistant Research

[+]

Amurensin G had significant antiangiogenic and antitumor growth effects in tamoxifen resistant breast cancer.Sep 30, 2012

Pubmed Data : Food Chem Toxicol. 2012 Oct ;50(10):3625-34. Epub 2012 Jul 27. PMID: 22842120
Article Published Date : Sep 30, 2012
Study Type : Human In Vitro
Additional Links
Substances : Amurensin G
Diseases : Breast Cancer, Breast Cancer: Drug Resistant
Pharmacological Actions : Anti-Angiogenic, Anti-Tumor, Antineoplastic Agents, Hypoxia-inducible factor-1 (HIF-1) inhibitor, Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords : Epigenetic Modification In Cancer, Gene Expression Regulation
[+]

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Pharmacol. 2010 Nov ;78(5):855-64. Epub 2010 Aug 16. PMID: 20713551
Article Published Date : Oct 31, 2010
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Amurensin G
Diseases : Breast Cancer: Drug Resistant, Cancers: Drug Resistant
Pharmacological Actions : Chemosensitizer
Additional Keywords : Gene Expression Regulation, Natural Substance/Drug Synergy, Plant Extracts
Problem Substances : Doxorubicin
[+]

"Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9."Dec 31, 2012

Pubmed Data : Molecules. 2013 ;18(1):701-20. Epub 2013 Jan 8. PMID: 23299550
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Breast Cancer: Drug Resistant
Pharmacological Actions : Chemosensitizer
Additional Keywords : Tamoxifen Resistance
[+]

"Insights into the cell of origin in breast cancer and breast cancer stem cells."May 31, 2010

Pubmed Data : Asia Pac J Clin Oncol. 2010 Jun ;6(2):89-97. PMID: 20565420
Article Published Date : May 31, 2010
Study Type : Review
Additional Links
Diseases : Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer Stem Cells, Cancer Stem Cells
Additional Keywords : Cancer Hypotheses, Cancer Stem Cells
[+]

"Progesterone Receptor Down-Regulates BCRP Expression via Binding to the Progesterone Response Element in Breast Cancer."Feb 20, 2012

Pubmed Data : Cancer Sci. 2012 Feb 20. Epub 2012 Feb 20. PMID: 22348324
Article Published Date : Feb 20, 2012
Study Type : In Vitro Study
Additional Links
Substances : Progesterone
Diseases : Breast Cancer: Drug Resistant, Cancers: Drug Resistant
Pharmacological Actions : Breast cancer resistance protein (BCRP) down-regulation
[+]

Antrodia cinnamomea extract inhibits the proliferation of tamoxifen-resistant breast cancer cells.May 08, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 May 9 ;18(1):152. Epub 2018 May 9. PMID: 29743060
Article Published Date : May 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Medicinal Mushrooms
Diseases : Breast Cancer, Breast Cancer: Drug Resistant
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Gamma-tocotrienol reverses multidrug resistance of breast cancer cells.Nov 14, 2016

Pubmed Data : J Steroid Biochem Mol Biol. 2016 Nov 15. Epub 2016 Nov 15. PMID: 27864002
Article Published Date : Nov 14, 2016
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol
Diseases : Breast Cancer: Drug Resistant
Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemosensitizer, Multidrug Resistance Gene Modulators
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin
[+]

Ganoderenic acid B has the potential to be developed into an ABCB1-mediated multidrug resistance reversal agent.Apr 30, 2015

Pubmed Data : Int J Oncol. 2015 May ;46(5):2029-38. Epub 2015 Mar 12. PMID: 25779097
Article Published Date : Apr 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Reishi Mushroom
Diseases : Breast Cancer: Drug Resistant, Cancers: Multi-Drug Resistant, Hepatoma: Multidrug Resistant
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Resistance Reversal
[+]

Oligosaccharides obtained from chia seeds enhanced vinblastine activity. Apr 19, 2017

Pubmed Data : Phytother Res. 2017 Apr 20. Epub 2017 Apr 20. PMID: 28425219
Article Published Date : Apr 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chia
Diseases : Breast Cancer: Drug Resistant
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Natural Substance/Drug Synergy
[+]

Quercetin reversed multidrug resistance in breast cancer cells.Apr 09, 2018

Pubmed Data : Phytother Res. 2018 Apr 10. Epub 2018 Apr 10. PMID: 29635751
Article Published Date : Apr 09, 2018
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Breast Cancer, Breast Cancer: Drug Resistant
Pharmacological Actions : Chemosensitizer, Multidrug Resistance Gene Modulators
[+]

Resveratrol exhibits anti-cancer properties against tamoxifen-resistant breast cancer cells.Sep 30, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : FASEB J. 2011 Oct ;25(10):3695-707. Epub 2011 Jul 7. PMID: 21737614
Article Published Date : Sep 30, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Breast Cancer: Drug Resistant
Pharmacological Actions : Estrogen Receptor Modulators, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Tamoxifen Resistance
Problem Substances : Tamoxifen
[+]

Sanguinarine as a potent inhibitor of dihydrofolate reductase, able to impair enzyme activity even in methotrexate resistant MDA-MB-231 cells.Jul 31, 2014

Pubmed Data : Biochem Pharmacol. 2014 Aug 1 ;90(3):226-34. Epub 2014 May 27. PMID: 24875448
Article Published Date : Jul 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Bloodroot
Diseases : Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Cyclin D1 Down-Regulation, Enzyme Inhibitors
Additional Keywords : Bloodroot, Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer: Triple Negative, Dose Response
[+]

Shikonin reduces tamoxifen resistance of MCF-7R breast cancer cells.Oct 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Oct 24 ;8(51):88658-88669. Epub 2017 Sep 11. PMID: 29179465
Article Published Date : Oct 23, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Breast Cancer, Breast Cancer: Drug Resistant
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
[+]

This study found that morphine contributes to chemoresistance via expanding the population of cancer stem cells and promotes tumor growth.Feb 27, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Feb 28 ;6(6):3963-76. PMID: 25686831
Article Published Date : Feb 27, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer, Breast Cancer: Drug Resistant, Breast Cancer Stem Cells
Additional Keywords : Cancer Stem Cells
Problem Substances : Morphine

Copyright: rob3000 / 123RF Stock Photo

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