Cancers: Drug Resistant

Name	AC	CK
Curcumin	73	105
Silibinin	6	33
Ginsenosides	15	27
EGCG (Epigallocatechin gallate)	18	21
Quercetin	17	20
Resveratrol	13	20
Wogonin	7	18
Flavonoids	13	17
Genistein	8	17
Beta-Elemene	13	16
Burdock	3	13
Capsaicin	3	12
Sulforaphane	6	12
Daidzein	2	11
Isoflavones	2	11
Amurensin G	2	10
Oridonin	8	10
Soy	1	10
Sumac	1	10
Apigenin	7	9
Berberine	7	9
Bufalin	6	9
Polyphenols	6	9
Vitamin C	8	9
NAC (N-acetyl-L-cysteine)	3	8
Shikonin	7	8
Licorice	5	7
Luteolin	5	7
Naringenin	5	7
Ursolic Acid	7	7
Cruciferous Vegetables	2	6
Cucurbitacin B	5	6
Honokiol	4	6
Indole-3-Carbinol	3	6
Lotus	5	6
Nobiletin	4	6
Parthenolide	6	6
Tanshinone IIA	6	6
Achiote	1	5
Baicalein	4	5
Emodin	4	5
Panax Notoginseng	1	5
Paprika	4	5
Vitamin C: Intravenous	1	5
Astragaloside	4	4
Betulinic acid	4	4
Carotenoids	3	4
Catechin	3	4
Celastrol	3	4
Fucoxanthin	2	4
Phloretin	3	4
Pterostilbene	3	4
Puerarin	2	4
Tangeretin	3	4
Thymoquinone	3	4
Xanthohumol	3	4
beta-Carotene	2	4
Artesunate	2	3
Barberry	3	3
Chrysin	3	3
Cucurbitacin D	3	3
DHA (Docosahexaenoic Acid)	3	3
Deguelin	3	3
Delphinidin	2	3
Ellagic Acid	3	3
Fisetin	2	3
Ginger	3	3
Ginkgo biloba	2	3
Isoliquiritigenin	2	3
Kaempferol	2	3
Lycopene	2	3
Mulberry	3	3
Nordihydroguaiaretic acid (NDGA)	3	3
Reishi Mushroom	3	3
Rosemaric Acid	2	3
Stilbenes	2	3
Theaflavins	3	3
Tripterygium wilfordii	2	3
AHCC	1	2
Adlay	1	2
Alpinia galanga	1	2
Antrodia camphorata	1	2
Arctigenin	2	2
Asiatic Acid	2	2
Asparagus	1	2
Bee Propolis	1	2
Benzyl isothiocyanate	2	2
Beta-Caryophyllene	1	2
Biochanin A	2	2
Bisdemethoxycurcumin	2	2
Cannabinoids	1	2
Canthaxanthin	1	2
Cholesterol	1	2
Cinnamic acid	1	2
Coenzyme Q10	1	2
Crocetin	2	2
Crocin	1	2
EPA (Eicosapentaenoic Acid)	2	2
Fermented Foods and Beverages	1	2
Green Tea	2	2
Hesperidin	1	2
Kefir	1	2
Lactobacillus plantarum	2	2
Lignans	1	2
Ligustrazine	1	2
Omega-3 Fatty Acids	2	2
Paeonol	1	2
Phellinus Linteus	2	2
Phenethyl isothiocyanate	2	2
Proanthocyanidins	2	2
Psychedelics:All	1	2
Rosemary	1	2
Rutin	2	2
Seaweed	1	2
Silymarin	2	2
Tannic Acid	1	2
Tea	1	2
Tetrahydrocurcumin	1	2
Tocotrienol: Gamma	2	2
Triptolide	2	2
Watercress	1	2
Zeaxanthin	1	2
acetyl-11-keto-beta-boswellic acid	1	2
6-Shogaol	1	1
Acerola	1	1
Agosterol A	1	1
Allicin	1	1
Antheraxanthin	1	1
Anthocyanins	1	1
Apple: Golden Delicious	1	1
Artemisinin	1	1
Ashwagandha	1	1
Bay leaf	1	1
Bee Venom	1	1
Beet	1	1
Berries: All	1	1
Beta Sitosterol	1	1
Birch	1	1
Bitter Melon	1	1
Black Raspberry	1	1
Black Tea	1	1
Bryostatin 1	1	1
Caffeic Acid	1	1
Caffeic acid phenethyl ester	1	1
Camptothecin	1	1
Cannabidiol	1	1
Capsorubin	1	1
Cardamonin	1	1
Carvacrol	1	1
Cashew	1	1
Catechols	1	1
Chokeberry	1	1
Citrus naringin	1	1
Clausena excavata	1	1
Cleistocalyx Operculatus	1	1
Coconut	1	1
Coconut Husk/Fiber	1	1
Cordyceps Militaris	1	1
Cucurbitacin E	1	1
Curcuminoids	1	1
Curcumol	1	1
Dandelion	1	1
Demethoxycurcumin	1	1
Ecteinascidin 743	1	1
Euphorbia	1	1
Farnesiferol A	1	1
Ferula Persica	1	1
Ferula Szowitsiana	1	1
Ferulic acid	1	1
Fish Oil	1	1
Frankincense	1	1
Galbanic Acid	1	1
Geraniol	1	1
Gingerol	1	1
Ginseng (Siberian)	1	1
Glucosamine	1	1
Gold (nanoparticles)	1	1
Gotu Kola	1	1
Grape	1	1
Grape Seed Extract	1	1
Guggul	1	1
Hedyotis corymbosa	1	1
Hedyotiscone A	1	1
Honey	1	1
Hu Zhang (Polygonum cuspidatum)	1	1
Japanese Raisin Tree	1	1
Kava Kava	1	1
Lactoferrin	1	1
Lobelia	1	1
Loquat	1	1
Lupeol	1	1
Lutein	1	1
Maca	1	1
Magnolia	1	1
Magnolia grandifloris (honokiol)	1	1
Mangosteen	1	1
Melatonin	1	1
Mistletoe	1	1
Mustard Oil	1	1
Myricetin	1	1
Neem	1	1
Oat Bran	1	1
Oleanolic acid	1	1
Oleuropein	1	1
Orange	1	1
Paeoniflorin	1	1
Peony	1	1
Persimmon	1	1
Piceatannol	1	1
Piperine	1	1
Piperlongumine	1	1
Progesterone	1	1
Red Sage	1	1
Sakuranetin	1	1
Schisandra	1	1
Selenium	1	1
Sipholane triterpenoids	1	1
St. Johns Wort	1	1
Thyme	1	1
Vitamin D	1	1
Vitamin E	1	1
Vitamin E: Gamma-tocotrienol	1	1
Vitamin E: alpha tocopherol	1	1
Welwitindolinones	1	1
Xanthones	1	1
cottonseed oil (gossypol)	1	1

Name	AC	CK
Doxorubicin	3	9
Nicotine	5	5
Adrenaline	3	4
Fluorouracil (5-FU or f5U)	2	4
Bisphenol A	3	3
Cisplatin	2	3
Carboplatin	1	2
Tamoxifen	2	2
Chemotherapy	1	1
Herceptin	1	1
Phthalates	1	1

Name	AC	CK	Focus
Cryotherapy	1	3
Light-Emitting Diodes (LEDs) Therapy	1	1

Name	AC	CK
Chemotherapy	4	6
Stress	3	4
Radiotherapy	2	3
Surgical Procedures	1	2

[+]

Fermented soy therapy may have therapeutic value in treating platinum-resistant ovarian cancer. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Gynecol Oncol. 2006 Jan;100(1):205-9. Epub 2005 Sep 19. PMID: 16171852

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Daidzein, Genistein, Isoflavones, Soy

Diseases : Cancers: Drug Resistant, Ovarian Cancer

Additional Keywords : Drug: Doxorubicin

[+]

Ginsenoside Rg3 could be used as a new regimen to delay acquired resistance of epidermal growth factor receptor-tyrosine kinase inhibitors.Oct 24, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2014 Mar 30 ;5(6):1621-34. PMID: 24742583

Article Published Date : Mar 29, 2014

Study Type : Human In Vitro

Additional Links

Substances : Cruciferous Vegetables, Sulforaphane

Diseases : Cancers: Drug Resistant, Pancreatic Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemotherapeutic

Additional Keywords : Cancer Stem Cells, Dietary Concentrations

[+]

Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.Jul 31, 2012

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 2012 Aug 1 ;84(3):402-10. Epub 2012 Mar 29. PMID: 22483777

Article Published Date : Jul 31, 2012

Study Type : Human In Vitro

Additional Links

Substances : Amurensin G

Diseases : Cancers: Drug Resistant, Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Cancer Stem Cells, Gene Expression Regulation, Natural Substance Synergy

[+]

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Pharmacol. 2010 Nov ;78(5):855-64. Epub 2010 Aug 16. PMID: 20713551

Article Published Date : Oct 31, 2010

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Amurensin G

Diseases : Breast Cancer: Drug Resistant, Cancers: Drug Resistant

Pharmacological Actions : Chemosensitizer

Additional Keywords : Gene Expression Regulation, Natural Substance/Drug Synergy, Plant Extracts

Problem Substances : Doxorubicin

[+]

Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(5):e0121538. Epub 2015 May 1. PMID: 25933112

Article Published Date : Dec 31, 2014

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Capsaicin

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Cholangiocarcinoma

Pharmacological Actions : Antineoplastic Agents, Apoptotic, Autophagy Inhibitors, Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells.Nov 03, 2016

Click here to read the entire abstract

Pubmed Data : Oncotarget. 2016 Nov 4. Epub 2016 Aug 4. PMID: 27825116

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxid Redox Signal. 2010 Oct 1 ;13(7):987-97. PMID: 20170403

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Adv Res. 2022 Sep 24. Epub 2022 Sep 24. PMID: 36167294

Article Published Date : Sep 23, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Breast Cancer, Cancers: Multi-Drug Resistant

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Tumor Microenvironment

[+]

Tangeretin synergizes with 5-fluorouracil to induce autophagy through MicroRNA-21 in colorectal cancer cells.Dec 31, 2021

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2022 ;50(6):1681-1701. Epub 2022 Jul 15. PMID: 35848125

Drug-induced expression of EpCAM contributes to therapy resistance in esophageal adenocarcinoma.Nov 30, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Oncol (Dordr). 2018 Dec ;41(6):651-662. Epub 2018 Aug 16. PMID: 30116994

Article Published Date : Nov 30, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Diseases : Cancers: Drug Resistant, Esophageal Cancer

Additional Keywords : Cancer Stem Cells, Risk Factors

Problem Substances : Cisplatin, Doxorubicin, Fluorouracil (5-FU or f5U)

[+]

EGCG enhances 5FU sensitivity in chemoresistant colorectal cancer by targeting cancer stem cells.Mar 28, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Toxicol In Vitro. 2019 Sep 5 ;61:104642. Epub 2019 Sep 5. PMID: 31493543

Article Published Date : Sep 04, 2019

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2008 Jul 8;265(2):289-97. Epub 2008 Apr 18. PMID: 18374481

Article Published Date : Jul 08, 2008

Study Type : Animal Study

Additional Links

Substances : Alpinia galanga, Flavonoids

Diseases : Cancers: Drug Resistant, Leukemia: Acute myelogenous leukemia (AML) , Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemosensitizer

[+]

Click here to read the entire abstract

Pubmed Data : Tumour Biol. 2015 Jun 23. Epub 2015 Jun 23. PMID: 26099723

Article Published Date : Jun 22, 2015

Study Type : Animal Study

Additional Links

Substances : Hesperidin

Diseases : Cancers: Drug Resistant, Ehrlich carcinoma

Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors

Problem Substances : Doxorubicin

[+]

Indole-3 carbinol reverses multidrug resistant melanoma in vivo. Feb 01, 1996

Pubmed Data : Int J Oncol. 2017 Nov ;51(5):1383-1394. Epub 2017 Sep 22. PMID: 29048624

Article Published Date : Oct 31, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Licorice

Diseases : Cancers: Drug Resistant, Gastric Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation

Additional Keywords : Plant Extracts

[+]

Luteolin could restore sensitivity of oxaliplatin resistant cell lines to chemotherapeutic drugs.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Exp Clin Cancer Res. 2017 12 22 ;36(1):190. Epub 2017 Dec 22. PMID: 29273065

Article Published Date : Jan 21, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

Puerarin enhances the anti-tumor effect of cisplatin on drug-resistant A549 cancer.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Oridonin induces apoptosis and reverses drug resistance in cisplatin resistant human gastric cancer cells.Jul 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Pharm Des. 2012 Feb 28. Epub 2012 Feb 28. PMID: 22390767

Article Published Date : Feb 28, 2012

Study Type : Review

Additional Links

Diseases : Brain Cancer Stem Cells, Breast Cancer Stem Cells, Cancer Stem Cells, Cancers: Multi-Drug Resistant, Colon Cancer Stem Cells

[+]

"Capsaicin induces apoptosis of cisplatin-resistant stomach cancer cells by causing degradation of cisplatin-inducible Aurora-A protein."Dec 31, 2010

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2011 ;63(7):1095-103. Epub 2011 Sep 20. PMID: 21932983

Article Published Date : Dec 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Capsaicin

Diseases : Cancers: Drug Resistant, Chemotherapy-Induced Toxicity: Cisplatin, Gastric Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemosensitizer, NF-kappaB Inhibitor

[+]

"Evolutionary malignant resistance of cells to damaging factors as common biological defence mechanism in neoplastic development."Sep 01, 2000

Click here to read the entire abstract

Pubmed Data : J Exp Clin Cancer Res. 2000 Sep ;19(3):335-48. PMID: 11144527

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Med. 2019 Sep ;44(3):1026-1038. Epub 2019 Jul 8. PMID: 31524219

Article Published Date : Aug 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Elecampane

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib.Aug 31, 2013

Click here to read the entire abstract

Pubmed Data : Apoptosis. 2013 Sep ;18(9):1060-70. PMID: 23613107

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Physiol Biochem. 2020 Aug 19 ;54(4):748-766. PMID: 32809300

Article Published Date : Aug 18, 2020

Study Type : In Vitro Study

Additional Links

Substances : Allicin

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Apoptotic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

[+]

Allyl isothiocyanate is a potential antiproliferative compound that modulates gene expression according to the tumor cell TP53 genotype.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Mutat Res. 2015 Jan ;771:29-35. Epub 2014 Dec 11. PMID: 25771977

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Can J Physiol Pharmacol. 2022 Aug 1 ;100(8):806-817. Epub 2022 Jun 15. PMID: 35704944

Article Published Date : Jul 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Apoptotic, Chemosensitizer

[+]

Anti-leukemia effect and mechanism of oridonin on omatinib-sensitive and imatinib-resistant K562 cells.Sep 30, 2017

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2019 Sep 26. Epub 2019 Sep 26. PMID: 31564411

Article Published Date : Sep 25, 2019

Study Type : In Vitro Study

Additional Links

Substances : Arctigenin

Diseases : Cancers: Multi-Drug Resistant, Colorectal Cancer

Pharmacological Actions : Autophagy Up-regulation, Chemosensitizer, Multidrug Resistance Gene Modulators

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Arctigenin is a novel therapeutic agent that inhibits resistance to etoposide associated with microenvironmental stress conditions.Apr 27, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Blood Cells Mol Dis. 2002 Mar-Apr;28(2):160-8. PMID: 12064912

Article Published Date : Mar 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Artesunate, Bufalin

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Leukemia

Pharmacological Actions : Antiproliferative , Chemosensitizer

[+]

Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation.Oct 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2022 Nov ;155:113705. Epub 2022 Oct 7. PMID: 36271541

Article Published Date : Oct 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Artesunate

Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer

[+]

Asiatic acid re-sensitizes multidrug-resistant A549/DDP cells to cisplatin.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Cell Physiol. 2018 Aug 26. Epub 2018 Aug 26. PMID: 30146689

Article Published Date : Aug 25, 2018

Study Type : In Vitro Study

Additional Links

Substances : Astragaloside

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Taxol, Natural Substance/Drug Synergy

[+]

Astragaloside IV sensitizes non-small cell lung cancer cells to gefitinib.Mar 31, 2017

Click here to read the entire abstract

Pubmed Data : Tumour Biol. 2017 Apr ;39(4):1010428317697555. PMID: 28443459

Click here to read the entire abstract

Pubmed Data : Oncol Rep. 2015 Dec ;34(6):2889-900. Epub 2015 Sep 23. PMID: 26397389

Article Published Date : Nov 30, 2015

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer, Cancers: Drug Resistant

Additional Keywords : Chemoresistance, Tumor Microenvironment

Problem Substances : Phthalates

[+]

Benzyl isothiocyanate induces apoptotic cell death in gefitinib-resistant NCI-H460 lung cancer cells.Aug 31, 2018

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2018 Sep ;38(9):5165-5176. PMID: 30194164

Article Published Date : Aug 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Benzyl isothiocyanate

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Isothiocyanates

[+]

Berberine maintains the neutrophil N1 phenotype to reverse cancer cell resistance to doxorubicin.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2019 ;10:1658. Epub 2020 Jan 29. PMID: 32063859

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2017 03 ;37(3):1191-1196. PMID: 28314281

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Beta-Caryophyllene

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Beta-elemene can inhibit breast cancer stem cells and the sphere-forming rate in MCF-7/ADM cells and reduce breast cancer resistance protein expression.Mar 26, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Camptothecin acts synergistically with imatinib and overcomes imatinib resistance in chronic myelogenous leukemia (CML) cells.Jul 08, 2007

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2007 Jul 8;252(1):75-85. Epub 2007 Jan 16. PMID: 17223257

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Lett. 2018 Jun ;15(6):9641-9646. Epub 2018 Apr 26. PMID: 29928339

Click here to read the entire abstract

Pubmed Data : Artif Cells Nanomed Biotechnol. 2018 Feb 6:1-12. Epub 2018 Feb 6. PMID: 29405784

Article Published Date : Feb 05, 2018

Study Type : In Vitro Study

Additional Links

Substances : Carvacrol

Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Inhibitors, Cell cycle arrest, Chemotherapeutic

[+]

Cashew contains an anticancer catechol with activity against multidrug resistant cancer cell lines.Apr 21, 2009

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2009 Apr 21;122(3):450-6. Epub 2009 Feb 10. PMID: 19429311

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : In Vivo. 2022 Sep-Oct;36(5):2020-2031. PMID: 36099129

Article Published Date : Aug 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Tripterygium wilfordii

Diseases : Cancers: Drug Resistant, Prostate Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Docetaxel

[+]

Chemosensitizing effect of nordihydroguaiaretic acid and its tetra-acetylated derivative on parental and multiresistant TA3 mouse mammary adenocarcinoma cells.Oct 31, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : In Vivo. 2009 Nov-Dec;23(6):959-67. PMID: 20023240

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Med. 2019 Dec 31. Epub 2019 Dec 31. PMID: 31891230

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Curcumin inhibits the survival of multiple myeloma cells. Apr 15, 2004

Click here to read the entire abstract

Pubmed Data : Blood. 2004 Apr 15;103(8):3175-84. Epub 2003 Dec 18. PMID: 15070700

Article Published Date : Apr 15, 2004

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Multiple Myeloma

Pharmacological Actions : Apoptotic, Interleukin-6 Downregulation, NF-kappaB Inhibitor

[+]

Curcumin is highlighted in overcoming therapeutic resistance and could be important for better treatment of lung cancer in combination therapy.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Adv Exp Med Biol. 2016 ;890:57-74. PMID: 26703799

Click here to read the entire abstract

Pubmed Data : Br J Haematol. 2005 Oct;131(1):59-66. PMID: 16173963

Article Published Date : Oct 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Lymphoma, Natural killer/T-cell lymphoma (NKTL)

Pharmacological Actions : Chemosensitizer, Enzyme Inhibitors, NF-kappaB Inhibitor

[+]

Curcumin may offer a therapeutic advantage in the clinical management of refractory bladder cancer. Oct 01, 2011

Click here to read the entire abstract

Pubmed Data : Cancer Prev Res (Phila). 2011 Oct ;4(10):1698-709. Epub 2011 Aug 11. PMID: 21836020

Click here to read the entire abstract

Pubmed Data : Zhonghua Xue Ye Xue Za Zhi. 2006 Apr;27(4):254-8. PMID: 16875558

Click here to read the entire abstract

Pubmed Data : Cancer Biol Ther. 2011 Jan 29;11(2). Epub 2011 Jan 29. PMID: 21088500

Article Published Date : Jan 29, 2011

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Melanoma

Pharmacological Actions : Chemosensitizer

[+]

Curcumin reduces multi-drug resistance in uterine cancer cells.Oct 01, 2008

Click here to read the entire abstract

Pubmed Data : Oncol Rep. 2008 Oct;20(4):731-5. PMID: 18813811

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2020 Oct ;34(10):2534-2556. Epub 2020 Apr 19. PMID: 32307747

Article Published Date : Sep 30, 2020

Study Type : Review

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Pharmacological Actions : Chemosensitizer

[+]

Curcumin sensitizes cervical cancer cells to curcumin-induced programmed cell death. Feb 25, 2005

Click here to read the entire abstract

Pubmed Data : J Biol Chem. 2005 Feb 25;280(8):6301-8. Epub 2004 Dec 7. PMID: 15590651

Click here to read the entire abstract

Pubmed Data : Mol Pharm. 2009 May-Jun;6(3):928-39. PMID: 19278222

Click here to read the entire abstract

Pubmed Data : Aging (Albany NY). 2021 11 5 ;13(21):24101-24116. Epub 2021 Nov 5. PMID: 34739394

Article Published Date : Jan 04, 2021

Study Type : In Vitro Study

Additional Links

Substances : Curcumol

Diseases : Cancers: Drug Resistant, Glioma

Pharmacological Actions : Antiproliferative

Additional Keywords : Epigenetic Modification In Cancer

[+]

Curcumol may be a potential chemical candidate for treating 5-Fu-resistant colorectal cancer.. Feb 27, 2023

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2023 Feb 28:1-18. Epub 2023 Feb 28. PMID: 36866798

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Biol Sci. 2022 ;18(9):3636-3652. Epub 2022 May 16. PMID: 35813479

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Daidzein

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gefitinib

[+]

Dandelion root has a potent action against chemoresistant melanoma without toxicity to healthy cells.Jan 01, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2011 ;2011:129045. Epub 2010 Dec 30. PMID: 21234313

Click here to read the entire abstract

Pubmed Data : Bioorg Med Chem. 2010 Apr 15;18(8):2964-75. Epub 2010 Mar 6. PMID: 20363142

Article Published Date : Apr 15, 2010

Study Type : In Vitro Study

Additional Links

Substances : Birch

Diseases : Cancers: Multi-Drug Resistant

Pharmacological Actions : Antineoplastic Agents, Chemosensitizer

Cancers: Drug Resistant jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

Cancers: Drug Resistant is a Sub of the following Topic

FREE Member Preview Enabled

View the Evidence: 612 Abstracts with Cancers: Drug Resistant Research

Limited to Members Only

Currently Available Sorting Options

Epstein-Barr virus infection may confer multidrug resistance to breast cancer cells. Sep 20, 1997

Fermented soy therapy may have therapeutic value in treating platinum-resistant ovarian cancer. Jan 01, 2006

Ginsenoside Rg3 could be used as a new regimen to delay acquired resistance of epidermal growth factor receptor-tyrosine kinase inhibitors.Oct 24, 2016

Of the 15 patients, 1 showed confirmed partial response and 4 patients had stable disease.Sep 28, 2016

Oral curcumin is safe and feasible in patients with pancreatic cancer.Sep 22, 2010

Rhus verniciflua stokes (Sumac) extract postively effects overall survival of patients with colorectal cancer refractory to conventional treatment. Jun 01, 2009

A diet rich in sulforaphane and related mustard oils may be considered as a supportive nutritional strategy to enhance therapeutic efficacy in patients suffering from pancreatic cancer.Mar 29, 2014

Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.Jul 31, 2012

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.Dec 31, 2014

Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells.Nov 03, 2016

Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer.Jan 29, 2017

Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.Dec 31, 2017

The annatto constituent cis-bixin has intriguing selective anti-myeloma activity.Sep 30, 2010

These results indicate that all analyzed cell lines including are highly sensitive to the cytotoxic, pro-oxidant effects of high doses of sodium ascorbate.Oct 31, 2015

Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.Jan 31, 2014

Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy.Jan 11, 2018

Enhanced therapeutic efficacy of doxorubicin against multidrug-resistant breast cancer with reduced cardiotoxicity.Nov 30, 2023

FBP1 induced by β-elemene enhances the sensitivity of gefitinib in lung cancer.Jan 31, 2023

Ginsenoside Rb1 for overcoming cisplatin-insensitivity of A549/DDP cells.Jun 30, 2023

Isorhamnetin induces cell cycle arrest and apoptosis in doxorubicin-resistant breast cancer.May 31, 2023

Paclitaxel-loaded ginsenoside Rg3 liposomes for drug-resistant cancer therapy.Sep 23, 2022

Tangeretin synergizes with 5-fluorouracil to induce autophagy through MicroRNA-21 in colorectal cancer cells.Dec 31, 2021

Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer.Jul 11, 2023

Two case reports of intravenous honokiol in drug-resistant cancer.Dec 31, 2019

Oridonin enhances the anticancer activity of NVP-BEZ235 against neuroblastoma cells in vitro and in vivo through autophagy.Jul 31, 2016

20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.Dec 31, 2018

A multiple-targets alkaloid nuciferine overcomes paclitaxel-induced drug resistance in vitro and in vivo.Sep 09, 2020

A variety of carotenoids induce reduce resistance to chemotherapy in multidrug resistant lymphoma and human breast cancer cell lines. Mar 01, 2004

Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells.Aug 30, 2018

AHCC improves treatment outcome and reduces side effects in anticancer drug treated mice. Jan 01, 2009

An antioxidant-rich extract of seaweed polyphenols combined with current PC treatment modalities may inhibit tumor relapse by targeting therapy-orchestrated autophagy in residual cells.Dec 31, 2014

Antrodia camphorata extract, when combined with anti-tumor agents, showed adjuvant antiproliferative effects on multi-drug resistant hepatoma. Aug 13, 2008

Apigenin could inhibit the growth of cisplatin-resistant colon cancer cells in vitro and in vivo.Feb 28, 2019

Baicalein reversed the resistance of human A549 lung adenocarcinoma cells to cisplatin.May 31, 2017

Berberine reverses breast cancer multidrug resistance.Apr 26, 2021

Bufalin could be an effective additional treatment to overcome acquired resistance to osimertinib in NSCLC cells.Sep 14, 2019

Chemosensitizing activities of cyclotides from Clitoria ternatea in paclitaxel-resistant lung cancer cells.Jan 31, 2013

Cholesterol derived from LDL acts as a chemosensitizer in multidrug resistant lymphoblastic leukemia cells.Oct 01, 2007

Cinnamic acid treatment increased the sensitivity of cancer stem cells to chemotherapeutic drugs through apoptosis.Dec 31, 2012

Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.Dec 31, 2015

Cucurbitacin B inhibits TGF-β1-induced epithelial-mesenchymal transition (EMT) in NSCLC.Feb 18, 2022

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.Sep 13, 2010

Curcumin has anticancer, chemosensitization and radiosensitization effects in prostate cancer.Mar 01, 2007

Curcumin holds promise as an adjuvant to broaden the spectrum of gefitinib therapy to improve the efficacy of gefitinib among the NSCLC patients with different EGFR status.Dec 31, 2010

Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human oral cancer cells.Sep 30, 2013

Dietary intake of watercress may help reverse cisplatin resistance in biliary tract cancer patients.Feb 29, 2016

Drug-induced expression of EpCAM contributes to therapy resistance in esophageal adenocarcinoma.Nov 30, 2018

EGCG enhances 5FU sensitivity in chemoresistant colorectal cancer by targeting cancer stem cells.Mar 28, 2016

Emodin alleviates gemcitabine resistance in pancreatic cancer.Oct 31, 2020

Emodin reverses resistance to gemcitabine in pancreatic cancer.Dec 31, 2022

Evaluation of inhibitory effects of flavonoids on breast cancer resistance protein.Sep 04, 2019

Exosomal miRNA-205 promotes breast cancer chemoresistance and tumorigenesis through E2F1.Jul 21, 2021

Fisetin inhibited tumor growth in athymic nude mouse xenograft model. Mar 24, 2018

Galangin, a compound found within Alpinia galanga, acts as a chemosensitizer in drug-resistant leukemia cells. Jul 08, 2008

Ginkgo biloba exocarp extracts could down regulate drug resistance related gene expression.Sep 30, 2016

Ginsenoside Rg3 in combination with artesunate overcomes sorafenib resistance in hepatoma cell and mouse models.Apr 30, 2022

Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter.Feb 29, 2020

Green tea (-)-epigalocatechin-3-gallate induces cell death in gastrointestinal stromal tumor including imatinib-resistant cells.Oct 01, 2009

Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer.Jul 01, 2010

Hesperidin as adjuvant therapy with DOX would enhance the therapeutic efficacy and alleviate the resistance to DOX in treatment of solid tumors.Jun 22, 2015

Indole-3 carbinol reverses multidrug resistant melanoma in vivo. Feb 01, 1996

Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells.Dec 31, 2014

Indole-3-carbinol would be effective for enhancing sensitivity of pancreatic cancer cells to gemcitabine.Mar 31, 2013

Isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells.Oct 31, 2014

Liquiritin induces apoptosis and autophagy in cisplatin-resistant gastric cancer cells.Oct 31, 2017

Luteolin could restore sensitivity of oxaliplatin resistant cell lines to chemotherapeutic drugs.Dec 31, 2013

Luteolin may be a potential candidate for NSCLC therapy, especially for treatment of patients with acquired erlotinib-resistant NSCLC.May 31, 2014

Modulation of antioxidant potential with coenzyme Q10 suppressed invasion of temozolomide-resistant glioma. Dec 31, 2018

Nobiletin reversed paclitaxel resistance in multi-drug resistance tumors.Nov 25, 2019

Oridonin inhibits gefitinib-resistant lung cancer cells.May 31, 2016

Cancers: Drug Resistant

View the Evidence:
612 Abstracts with Cancers: Drug Resistant Research