Carcinoma: Non-Small-Cell Lung

Name	AC	CK
Curcumin	15	20
Ginsenosides	3	13
Mistletoe	2	11
Traditional Chinese Medicine: Dixiong Decoction	1	10
Vitamin D	1	10
Water: Deuterium Depleted	1	10
Baicalein	2	7
Chaga Mushroom (Inonotus obliquus)	6	7
Silibinin	3	7
Cucurbitacin B	5	6
Deguelin	6	6
Ginger	2	6
Flavonoids	5	5
Luteolin	4	5
Noni leaf extract	2	4
Tanshinone IIA	4	4
Anthocyanins	2	3
Astragaloside	3	3
Berberine	3	3
Beta-Elemene	3	3
Cannabinoids: Synthetic	2	3
Cinnamaldehyde	2	3
EGCG (Epigallocatechin gallate)	2	3
Magnolol	2	3
Medicinal Mushrooms	2	3
Nobiletin	2	3
Phloretin	2	3
Quercetin	2	3
Shikonin	3	3
Sulforaphane	2	3
6-Shogaol	1	2
Adlay	2	2
Astaxanthin	2	2
Bisdemethoxycurcumin	2	2
Carvacrol	2	2
Chlorogenic Acid	2	2
Chrysin	1	2
Cordyceps Militaris	2	2
Fucoidan	1	2
Ginkgo biloba	2	2
Lotus	1	2
Mangiferin	1	2
Noni	1	2
Prunella vulgaris	1	2
Pterostilbene	1	2
Puerarin	1	2
Resveratrol	2	2
Salvia miltiorrhiza	1	2
Trichosanthes Kirilowii	1	2
Anandamide	1	1
Andrographis	1	1
Apigenin	1	1
Artemisinin	1	1
Artesunate	1	1
Beans: All	1	1
Bergamot orange	1	1
Betulinic acid	1	1
Bitter Orange	1	1
Cannabinoids	1	1
Catechin	1	1
Cinnamon	1	1
Citrus naringin	1	1
Cryptomeria japonica	1	1
Cucurbitacin D	1	1
Dandelion	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Demethoxycurcumin	1	1
Diosgenin	1	1
Fisetin	1	1
Gac	1	1
Gallic Acid	1	1
Genistein	1	1
Glycyrrhizin	1	1
Grape Seed Extract	1	1
Gynostemma	1	1
Holy Basil	1	1
Homeopathic Medicine: All	1	1
Honokiol	1	1
Hyperforin	1	1
Isoliquiritigenin	1	1
Litchi	1	1
Lutein	1	1
Magnolia	1	1
Melatonin	1	1
Mushrooms: All	1	1
Nettle	1	1
Oregano	1	1
Parthenolide	1	1
Phenethyl isothiocyanate	1	1
Piceatannol	1	1
Polyphenols	1	1
Pomegranate	1	1
Pomegranate Seed	1	1
Prickly Pear Cactus	1	1
Rose	1	1
Savory	1	1
Silver (nanoparticles)	1	1
Tea	1	1
Tetrahydrocurcumin	1	1
Thyme	1	1
Thymoquinone	1	1
Tocotrienol: Delta	1	1
Vanillin	1	1
Vitamin B-6	1	1
Vitexins	1	1
Wheat Grass	1	1
White Tea	1	1

Name	AC	CK	Focus
Cisplatin	2	3
Benzo(a)pyrene	1	2

Name	AC	CK	Focus
Traditional Chinese Medicine	1	10

[+]

The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer. Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Tradit Chin Med. 2013 Aug ;33(4):433-8. PMID: 24187861

Article Published Date : Jul 31, 2013

Study Type : Human Study

Additional Links

Diseases : Cancer Mortality, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Therapeutic Actions : Traditional Chinese Medicine

Pharmacological Actions : Antineoplastic Agents

Additional Keywords : Significant Treatment Outcome

[+]

Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2018 ;13(8):e0203058. Epub 2018 Aug 27. PMID: 30148853

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Mistletoe

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Chemotherapeutic

[+]

Plasma 25(OH)D deficiency is significantly associated with a higher risk of NSCLC, specifically late stage NSCLC.Aug 30, 2015

Click here to read the entire abstract

Pubmed Data : Cancer Biomark. 2015 Aug 31 ;15(5):663-8. PMID: 26406955

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Cancer. 2013 ;65(2):240-6. PMID: 23441611

Article Published Date : Dec 31, 2012

Study Type : Animal Study, Human Study

Additional Links

Substances : Water: Deuterium Depleted

Diseases : Carcinoma: Non-Small-Cell Lung, Carcinoma: Small Cell Lung, Lung Cancer, Lung Cancer: Metastatic

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Gene Expression Regulation, Proto-oncogene

[+]

6-gingerol a component of ginger is extensively metabolized in H-1299 human lung cancer cells.Nov 13, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Agric Food Chem. 2012 Nov 14 ;60(45):11372-7. Epub 2012 Nov 6. PMID: 23066935

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2018 Aug ;97(31):e11291. PMID: 30075496

Article Published Date : Jul 31, 2018

Study Type : Human: Case Report

Additional Links

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Additional Keywords : Spontaneous Regression

[+]

Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy.Jan 11, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2017 Mar 22 ;200:107-116. Epub 2017 Jan 12. PMID: 28088493

Article Published Date : Mar 21, 2017

Study Type : Animal Study

Additional Links

Substances : Salvia miltiorrhiza

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Apoptotic, P21 Activation, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Plant Extracts

[+]

Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Combinations of nobiletin with paclitaxel and carboplatin significantly suppressed the growth of subcutaneous A549 tumors xenografts in nude mice.Mar 31, 2014

Click here to read the entire abstract

Pubmed Data : Planta Med. 2014 Apr ;80(6):452-7. Epub 2014 Mar 31. PMID: 24687742

Article Published Date : Mar 31, 2014

Study Type : Animal Study

Additional Links

Substances : Nobiletin

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Drug: Carboplatin, Natural Substance/Drug Synergy, Plant Extracts

[+]

Curcumin holds promise as an adjuvant to broaden the spectrum of gefitinib therapy to improve the efficacy of gefitinib among the NSCLC patients with different EGFR status.Dec 31, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2011 ;6(8):e23756. Epub 2011 Aug 17. PMID: 21858220

Article Published Date : Dec 31, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Epidermal growth factor receptor (EGFR) inhibitor

Additional Keywords : Chemotherapeutic Synergy: Gefitinib

[+]

Delivery of paeonol by nanoparticles enhances its in vitro and in vivo antitumor effects.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Acta Pharmacol Sin. 2017 Aug 24. Epub 2017 Aug 24. PMID: 28836581

Article Published Date : Aug 23, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Mitomycin C

[+]

Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.Nov 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Pterostilbene exerts anticancer activity on non-small-cell lung cancer.Aug 13, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Cancer. 2016 Sep 1 ;16:707. Epub 2016 Aug 1. PMID: 27586635

Article Published Date : Aug 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative

[+]

This study provides new insights into cucurbitacin B mediated epigenetic alterations and its chemotherapeutic effects on lung cancer.May 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Regul Toxicol Pharmacol. 2016 Sep 28. Epub 2016 Aug 28. PMID: 27693704

Article Published Date : Sep 27, 2016

Study Type : In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

A methanolic extract of C. militaris at the concentration significantly inhibited cell proliferation and induced apoptosis of NCI-H460 cells.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2015 ;20(8):13927-40. Epub 2015 Jul 31. PMID: 26263965

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2014 ;14:419. Epub 2014 Oct 27. PMID: 25345853

Click here to read the entire abstract

Pubmed Data : Tumour Biol. 2017 Apr ;39(4):1010428317697555. PMID: 28443459

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Manag Res. 2019 ;11:9005-9015. Epub 2019 Oct 21. PMID: 31695492

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator

[+]

Bergamottin isolated from Citrus bergamia exerts in vitro and in vivo antitumor activity in lung adenocarcinoma.Jun 30, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Study Type : In Vitro Study

Additional Links

Substances : Bisdemethoxycurcumin, Curcumin

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer, Lung Cancer: Metastatic

Pharmacological Actions : Anti-metastatic, Wnt/β-catenin pathway down-regulation

[+]

C-phycocyanin suppresses the in vitro proliferation and migration of non-small-cell lung cancer cells.Jun 17, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mar Drugs. 2019 Jun 18 ;17(6). Epub 2019 Jun 18. PMID: 31216707

Click here to read the entire abstract

Pubmed Data : Anticancer Drugs. 2019 Mar ;30(3):241-250. PMID: 30640793

Article Published Date : Feb 28, 2019

Study Type : In Vitro Study

Additional Links

Substances : Cardamonin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Carnosic acid has the potential to inhibit cancer cell growth in A-549 lung cancer cells.Oct 20, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nat Prod. 2014 Jan 24 ;77(1):35-41. Epub 2013 Dec 20. PMID: 24359303

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2017 Jun 10 ;329:272-281. Epub 2017 Jun 10. PMID: 28610991

Article Published Date : Jun 09, 2017

Study Type : In Vitro Study

Additional Links

Substances : Cucurbitacin B

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Chemotherapeutic

Additional Keywords : Chemothapeutic Synergy: Paclitaxel

[+]

Cucurbitacin D overcomes gefitinib resistance in gefitinib-resistant NSCLC cells.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Eugenol inhibits non-small cell lung cancer by repressing expression of NF-κB-regulated TRIM59.Apr 30, 2019

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2019 May ;33(5):1562-1569. Epub 2019 Apr 1. PMID: 30932261

Article Published Date : Apr 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Eugenol

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antiproliferative , NF-kappaB Inhibitor

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Mar 26. Epub 2016 Mar 26. PMID: 27029077

[+]

Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells.Mar 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Rep. 2012 Apr ;27(4):959-64. Epub 2012 Jan 4. PMID: 22227970

Article Published Date : Mar 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Deguelin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antineoplastic Agents, Tumor Suppressor Protein p53 Upregulation

[+]

Induction of the cell cycle arrest and apoptosis by flavonoids isolated from Korean Citrus aurantium L. in non-small-cell lung cancer.Dec 14, 2012

Click here to read the entire abstract

Pubmed Data : Food Chem. 2012 Dec 15 ;135(4):2728-35. Epub 2012 Jul 6. PMID: 22980865

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biol Chem. 2014 Dec 26 ;289(52):35839-48. Epub 2014 Nov 3. PMID: 25368326

Article Published Date : Dec 25, 2014

Study Type : In Vitro Study

Additional Links

Substances : Isoliquiritigenin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic, Epidermal growth factor receptor (EGFR) inhibitor

[+]

Lentinan-based chemo-immunotherapy is a promising strategy for anti-tumor via enhancing the proliferation of cytotoxic T cells.Nov 19, 2018

Click here to read the entire abstract

Pubmed Data : Pathol Oncol Res. 2018 Nov 20. Epub 2018 Nov 20. PMID: 30460541

Article Published Date : Nov 19, 2018

Study Type : In Vitro Study

Additional Links

Substances : Lentinan

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Immunomodulatory

[+]

Licochalcone A inhibits EGFR signalling and translationally suppresses survivin expression in human cancer cells.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Braz J Med Biol Res. 2020 ;54(2):e9017. Epub 2020 Dec 18. PMID: 33331417

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bee Venom

Diseases : Cancer Metastasis, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Transforming growth factor beta (TGF-β) inhibitor

[+]

Metabolites of fruiting bodies of Xylaria sp are a natural source of antibacterial and anticancer agents.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Int J Med Mushrooms. 2015 ;17(10):1005-17. PMID: 26756192

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2017 Jan ;15(1):309-316. Epub 2016 Dec 5. PMID: 27922683

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Rep. 2018 Dec ;40(6):3458-3468. Epub 2018 Oct 2. PMID: 30542737

Article Published Date : Nov 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Phenethyl isothiocyanate and cisplatin co-encapsulated in a liposomal nanoparticle for treatment of non-small cell lung cancer.Feb 21, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Tanshinone IIA combined with adriamycin inhibited malignant biological behaviors of NSCLC A549 cell line.Jan 17, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Cancer. 2016 11 18 ;16(1):899. Epub 2016 Nov 18. PMID: 27863471

Click here to read the entire abstract

Pubmed Data : Int J Oncol. 2016 May ;48(5):2205-12. Epub 2016 Mar 15. PMID: 26983803

Article Published Date : Apr 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer

[+]

Tanshinone IIA reverses gefitinib-resistance in human non-small-cell lung cancer.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anticancer Res. 2012 Jul ;32(7):2647-55. PMID: 22753722

Article Published Date : Jun 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Tocotrienol: Delta

Diseases : Carcinoma: Non-Small-Cell Lung, Chemotherapy-Induced Toxicity: Cisplatin, Lung Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Chemosensitizer, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Dose Response

[+]

The proapoptotic effects of curcumin depend on miR-192-5p/215 induction and the p53-miR-192-5p/215-XIAP pathway is an important therapeutic target for non small cell lung cancer.Jan 31, 2015

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2015 Feb 1 ;357(1):196-205. Epub 2014 Nov 18. PMID: 25444916

Article Published Date : Jan 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Apoptotic, MicroRNA modulator, Tumor Suppressor Protein p53 Upregulation

[+]

The root bark of Morus alba L. suppressed the migration of human non-small-cell lung cancer.May 06, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 May 7 ;20(9). Epub 2019 May 7. PMID: 31067694

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2015 Jun ;29(6):844-9. Epub 2015 Mar 6. PMID: 25753585

Article Published Date : May 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Galbanic Acid

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Apoptotic

[+]

These results demonstrate that astragaloside IV enhances chemosensitivity to cisplatin.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Physiol Biochem. 2016 ;40(5):1221-1229. Epub 2016 Dec 14. PMID: 27960166

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Astragaloside

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

These results demonstrate that morusin induced apoptosis in human NSCLC cells.Jan 19, 2018

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2018 10 20 ;505(1):194-200. Epub 2018 Sep 19. PMID: 30243717

Article Published Date : Jan 19, 2018

Study Type : In Vitro Study

Additional Links

Substances : Mulberry

Diseases : Cancers: Drug Resistant, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

These results demonstrated that the anti-proliferative effects of panaxydol were caused by cell cycle arrest.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2018 ;41(11):1701-1707. PMID: 30381670

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Ginseng

Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest

Additional Keywords : Phytotherapy, Plant Extracts

[+]

These results indicated that M. oleifera alkaloid extract inhibits the proliferation and migration of A549 cells.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Pharmacol Rep. 2020 Oct 23. Epub 2020 Oct 23. PMID: 33095436

Article Published Date : Oct 22, 2020

Study Type : In Vitro Study

Additional Links

Substances : Thymol

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest

[+]

Thymoquinone and cisplatin appear to be an active therapeutic combination in lung cancer.Jun 30, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Exp Clin Cancer Res. 2010 Jul 1 ;29:87. Epub 2010 Jul 1. PMID: 20594324

Article Published Date : Jun 30, 2010

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Cancer Metastasis, Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Total ginsenosides extract induce autophagic cell death in NSCLC cells through activation of endoplasmic reticulum stress.Jul 16, 2019

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2019 Jul 17 ;243:112093. Epub 2019 Jul 17. PMID: 31325602

Article Published Date : Jul 16, 2019

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

[+]

Tricetin, suppresses benzo(a)pyrene induced human non small cell lung cancer bone metastasis.Apr 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Oncol. 2015 May ;46(5):1985-93. Epub 2015 Mar 4. PMID: 25738754

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Benzo[a]pyrene-induced Toxicity , Carcinoma: Non-Small-Cell Lung, Lung Cancer

Pharmacological Actions : Anti-metastatic, Chemotherapeutic

Additional Keywords : Macrophage Colony-Stimulating Factor

[+]

Ursolic Acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in NSCLCs harboring EGFR T790M.Jul 18, 2019

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2019 Jul 19. Epub 2019 Jul 19. PMID: 31322286

Article Published Date : Jul 18, 2019

Study Type : In Vitro Study

Additional Links

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Urtica dioica L. inhibits proliferation and enhances cisplatin cytotoxicity in NSCLC cells.Mar 20, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nat Prod. 2016 Jan 22 ;79(1):156-60. Epub 2015 Dec 17. PMID: 26681550

Article Published Date : Jan 21, 2016

Study Type : In Vitro Study

Additional Links

Substances : Ginger

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Anti-metastatic, Chemotherapeutic

[+]

β-elemene is a promising anti-cancer therapeutic candidate for tyrosine kinase inhibitors-resistant NSCLC.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cancer. 2021 ;12(8):2285-2294. Epub 2021 Feb 22. PMID: 33758606

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Beta-Elemene

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Erlotinib

[+]

Turkey tail mushroom extract appears to slow the progression of advanced non-small cell lung cancer.May 16, 2011

Click here to read the entire abstract

Pubmed Data : Curr Med Chem. 2011 May 16. Epub 2011 May 16. PMID: 12814145

Article Published Date : May 16, 2011

Additional Links

Diseases : Carcinoma: Non-Small-Cell Lung

Carcinoma: Non-Small-Cell Lung jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 260 Abstracts with Carcinoma: Non-Small-Cell Lung Research

Limited to Members Only

Currently Available Sorting Options

The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer. Dec 31, 2019

C-reactive protein is a significant predictor of improved survival in patients with advanced non-small cell lung cancer.May 31, 2019

Exposure to high levels BPA may be associated with non-small cell lung cancer.Aug 31, 2020

Ginsenoside Rg3 could be used as a new regimen to delay acquired resistance of epidermal growth factor receptor-tyrosine kinase inhibitors.Oct 24, 2016

Integrated Chinese-western therapy was superior to western therapy alone with significant survival differences. Jul 31, 2013

Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy.Dec 31, 2017

Plasma 25(OH)D deficiency is significantly associated with a higher risk of NSCLC, specifically late stage NSCLC.Aug 30, 2015

Systemic immune-inflammation could represent an independent prognostic factor for patients with resectable NSCLC.Apr 30, 2018

The early application of the Chinese herbal decoction compound Dixiong Decoction can decrease the incidence of radiation pneumonitis, reduce the injury of the lung, and improve the life quality of the patients.Oct 01, 2010

The median survival time of patients in the deuterium depleted water consuming group was 2-4 times longer than it is generally observed in lung cancer patients.Dec 31, 2012

6-gingerol a component of ginger is extensively metabolized in H-1299 human lung cancer cells.Nov 13, 2012

Baicalein induces caspase-dependent apoptosis in human lung carcinoma A549 cells.Feb 29, 2016

Curcumin inhibited the migratory and invasive ability of A549 cells via the inhibition of adiponectin expression.Dec 31, 2014

A case report of spontaneous regression of locally advanced nonsmall cell lung cancer.Jul 31, 2018

Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy.Jan 11, 2018

Spontaneous regression of non-small cell lung cancer after biopsy of a mediastinal lymph node metastasis.Sep 16, 2015

Xanthohumol targets the ERK1/2‑Fra1 signaling axis to reduce cyclin D1 expression and inhibit non‑small cell lung cancer.Jul 19, 2020

A methanol extract of Salvia miltiorrhiza Bunge induced apoptosis in non-small cell lung cancer.Mar 21, 2017

Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3.Dec 31, 2020

Berberine chloride suppresses non-small cell lung cancer. Jun 30, 2020

Biochanin A regulates the growth and migration of NSCLC through suppressing the VEGF/VEGFR2 signaling pathway.Jul 22, 2018

Chaga mushroom and its compounds could be used as natural anticancer ingredients.May 31, 2010

Chloroform extracts of Cordyceps taii have potent in vivo antitumor and antimetastatic activities.Dec 31, 2014

Chrysin strengthened the therapeutic efficacy of docetaxel and diminished the adverse effect of it.May 04, 2016

Cinnamaldehyde induces cell apoptosis in non-small cell lung cancer.Nov 24, 2017

Combination effects of ellagic acid with erlotinib in a Ba/F3 cell line expressing EGFR H773_V774 insH mutation.Dec 31, 2019

Combinations of nobiletin with paclitaxel and carboplatin significantly suppressed the growth of subcutaneous A549 tumors xenografts in nude mice.Mar 31, 2014

Curcumin holds promise as an adjuvant to broaden the spectrum of gefitinib therapy to improve the efficacy of gefitinib among the NSCLC patients with different EGFR status.Dec 31, 2010

Delivery of paeonol by nanoparticles enhances its in vitro and in vivo antitumor effects.Dec 31, 2016

Didymin induces Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells.May 31, 2010

Fucoidan could inhibit of lung cancer in vivo and in vitro.Sep 14, 2014

Ginsenosides synergize with mitomycin C in combating human non-small cell lung cancer.Aug 23, 2017

Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.Nov 30, 2019

Luteolin may be a potential candidate for NSCLC therapy, especially for treatment of patients with acquired erlotinib-resistant NSCLC.May 31, 2014

Mangiferin may be considered a potential antineoplastic drug for the future treatment of cancer.Mar 31, 2016

Melittin induces NSCLC apoptosis via inhibition of miR-183.Dec 31, 2017

Morinda citrifolia leaf was more effective than the erlotinib in suppressing lung adenocarcinoma in mice. Jan 13, 2016

Noni leaf extract at 300mg/kg was more effective than Erlotinib for most of the parameters measured in this study. Apr 21, 2016

Nuciferine not only inhibited the growth of NSCLC cells, but also remarkably alleviated the injury induced by nicotine in liver function.May 12, 2015

Oridonin inhibits gefitinib-resistant lung cancer cells.May 31, 2016

Parthenolide inhibits the growth of non-small cell lung cancer by targeting epidermal growth factor receptor.Nov 22, 2020

Phloretin is able to inhibit NSCLC A549 cell growth by inducing apoptosis.Nov 30, 2015

Prunella vulgaris has potential as a lung cancer chemopreventive agent.Dec 31, 2009

Pterostilbene exerts anticancer activity on non-small-cell lung cancer.Aug 13, 2017

Puerarin suppressed the invasion and migration of NSCLC macrophages, restrained the expression of angiogenesis factors.Jan 31, 2017

Quercetin suppresses the metastatic ability of lung cancer.Jan 09, 2017

Repression of hexokinases II-mediated glycolysis contributes to piperlongumine-induced tumor suppression in non-small cell lung ccancer cells.Dec 31, 2018

Sulforaphane is a novel inhibitory modulator of EGFR expression and is effective in inhibiting the tumor growth of EGFR-TKI-resistant NSCLC cells.Dec 31, 2014

Suppression of lung cancer progression by isoliquiritigenin through its metabolite 2, 4, 2', 4'-Tetrahydroxychalcone.Oct 02, 2018

Synthetic cannabinoids inhibited growth, migration and invasion of NSCLC cells in in vitro as well as in vivo in a mouse model.Dec 31, 2010

The current study clearly indicates that 6-shogaol can be exploited for the prevention and treatment of NSCLC.Feb 28, 2014

These findings identify Magnolol as a promising candidate with anti-microtubule polymerization activity for NSCLC treatment.Jul 25, 2017

This study established a new mechanism for using EGCG as an adjuvant chemotherapy agent through modifying microvasculature and microenvironments. Apr 30, 2013

This study is the first to demonstrate efficacy of baicalein both in-vitro and in-vivo in NSCLC. Aug 31, 2016

This study provides new insights into cucurbitacin B mediated epigenetic alterations and its chemotherapeutic effects on lung cancer.May 31, 2015

TKM fruits significantly suppressed NSCLC cell proliferation, migration, invasion, tumorigenicity and tumor growth, and significantly extending survival time of NSCLC-bearing mice.Dec 31, 2014

Synergistic killing effect of paclitaxel and honokiol in non-small cell lung cancer cells through paraptosis induction.Sep 15, 2020

(-)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells.Dec 31, 2018

A combination of pemetrexed and astaxanthin resulted in synergistic enhancing cytotoxicity and cell growth inhibition in NSCLC cells.Sep 27, 2016

A methanolic extract of C. militaris at the concentration significantly inhibited cell proliferation and induced apoptosis of NCI-H460 cells.Dec 31, 2014

A polysaccharide fraction of adlay seed induces apoptosis in human non-small cell lung cancer A549 cells.Jan 10, 2013

A review on the effects of current chemotherapy drugs and natural agents in treating non-small cell lung cancer.Nov 30, 2017

Acanthopanax senticosus polysaccharide suppressed the proliferation and metastasis of the human non-small cell lung cancer NCI-H520 cells.Jul 22, 2019

Acetyl-11-keto-β-boswellic acid exerts the anti-cancer effects via cell cycle arrest, apoptosis induction, and autophagy suppression in NSCLC cells.Dec 31, 2019

Advanced glycation end-products enhance lung cancer cell invasion and migration.Aug 08, 2016

Aloe-emodin induces autophagy and apoptotic cell death in non-small cell lung cancer cells.Nov 04, 2020

An extract of holy basil significantly inhibited cell adhesion and invasion at nontoxic concentrations.Dec 31, 2013

Andrographis contains a compound which inhibits migration and invasion in human non-small lung cancer cells.Apr 25, 2010

Antioxidant property of Taraxacum formosanum Kitam and its antitumor activity in non-small-cell lung cancer cells.Sep 30, 2018

Artesunate could suppress lung-tumor progression by inhibiting Wnt/β-catenin pathway.Apr 21, 2016

Astragaloside IV inhibits the progression of non-small cell lung cancer.Aug 20, 2018

Astragaloside IV sensitizes non-small cell lung cancer cells to cisplatin.Jun 30, 2020

Carcinoma: Non-Small-Cell Lung

View the Evidence:
260 Abstracts with Carcinoma: Non-Small-Cell Lung Research