Cardiotoxicity: Chemotherapy-Induced

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9 Substances Researched for Cardiotoxicity: Chemotherapy-Induced
NameACCKFocus
Oleuropein24Locked
Bee Propolis12Locked
Caffeic acid phenethyl ester12Locked
Grape Seed Extract12Locked
Panax Notoginseng12Locked
Pomegranate12Locked
Spirulina12Locked
Vitamin E: alpha tocopherol12Locked
Chrysin11Locked
1 Problematic Actions Researched for Cardiotoxicity: Chemotherapy-Induced
NameACCKFocus
Chemotherapy11Locked
Related Topics

Cardiotoxicity: Chemotherapy-Induced is a Sub of the following Topic

View the Evidence:
12 Abstracts with Cardiotoxicity: Chemotherapy-Induced Research

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Caffeic acid phenetyl ester, a compound found within bee propolis, protects against doxorubucin-induced cardiotoxicity in rats. Sep 30, 2010

Pubmed Data : Am J Ind Med. 2010 Sep 30. Epub 2010 Sep 30. PMID: 14745846
Article Published Date : Sep 30, 2010
Study Type : Animal Study
Additional Links
Substances : Bee Propolis, Caffeic acid phenethyl ester
Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Antioxidants
Additional Keywords : Drug: Doxorubicin
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Grape seed extract has a protective role against doxorubicin-induced cardiotoxicity and genotoxicity in albino mice.Aug 01, 2010

Pubmed Data : J Med Food. 2010 Aug;13(4):917-25. PMID: 20553142
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity: Doxorubicin, DNA damage
Pharmacological Actions : Cardioprotective, Genoprotective
Additional Keywords : Drug: Doxorubicin
[+]

Oleuropein confers protection against doxorubicin-induced cardiotoxicity. Jul 01, 2009

Pubmed Data : NMR Biomed. 2009 Jul;22(6):585-92. PMID: 19308947
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Antihypertensive Agents, Antioxidants
Additional Keywords : Drug: Doxorubicin
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Oleuropein prevents doxorubicin-induced cardiotoxicity and improves therapeutic outcome. Mar 01, 2007

Pubmed Data : J Mol Cell Cardiol. 2007 Mar;42(3):549-58. Epub 2007 Jan 16. PMID: 17223128
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin, Oxidative Stress
Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies
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Panax Notoginseng has a protective effect against doxorubicin-induced cardiotoxicity in mice. Feb 01, 2008

Pubmed Data : Planta Med. 2008 Feb;74(3):203-9. Epub 2008 Feb 8. PMID: 18260050
Article Published Date : Feb 01, 2008
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng
Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective
Additional Keywords : Drug Side Effect Attenuation
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Pomegranate demonstrated significant cardioprotection against daunorubicin-induced cardiotoxicity.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2016 ;7:85. Epub 2016 Jun 20. PMID: 27413516
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy and Radiation Toxicity, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Malondialdehyde Down-regulation
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Spirulina has a protective effect against doxorubicin-induced cardiotoxicity in mice. Dec 01, 2005

Pubmed Data : Phytother Res. 2005 Dec;19(12):1030-7. PMID: 16372368
Article Published Date : Dec 01, 2005
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Cardioprotective
Additional Keywords : Drug-Plant-Vitamin Synergies, Drug Side Effect Attenuation
[+]

Supplementation of vitamin E may improve the efficacy of standard and experimental cancer therapies by subsiding the toxic effect of the antineoplastic agent.Mar 31, 2015

Pubmed Data : Hum Exp Toxicol. 2015 Apr ;34(4):380-9. Epub 2014 Oct 10. PMID: 25304969
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Vitamin E: alpha tocopherol
Diseases : Cardiotoxicity: Chemotherapy-Induced, Oxidative Stress
Pharmacological Actions : Antioxidants, Cardioprotective, Chemoprotective Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Cancer chemotherapy induces cardiotoxicity by targeting cardiac stem cells.Oct 31, 2010

Pubmed Data : J Cell Mol Med. 2010 Nov ;14(11):2630-2. PMID: 20874720
Article Published Date : Oct 31, 2010
Study Type : Review
Additional Links
Diseases : Cancers: Pediatric, Cardiac Mortality , Cardiotoxicity: Chemotherapy-Induced
Additional Keywords : Cardiac Stem Cells
Anti Therapeutic Actions : Chemotherapy
Adverse Pharmacological Actions : Cardiotoxic
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Chrysin inhibits mitoxantrone triggered cardiomyocyte apoptosis via multiple pathways. Nov 30, 2015

Pubmed Data : Histol Histopathol. 2015 Dec ;30(12):1465-75. Epub 2015 Jun 26. PMID: 26112963
Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chrysin
Diseases : Cardiotoxicity: Chemotherapy-Induced
Pharmacological Actions : Bax/Bcl2 Ratio: Decrease, Cardioprotective, Chemoprotective Agents
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Crocin ameliorates arsenic trioxide‑induced cardiotoxicity.Sep 09, 2020

Pubmed Data : Biomed Pharmacother. 2020 Sep 10 ;131:110713. Epub 2020 Sep 10. PMID: 32920515
Article Published Date : Sep 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Crocin
Diseases : Cardiotoxicity: Chemotherapy-Induced
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Arsenic Trioxide
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Ellagic acid may provide benefit in reducing oxidative injury and cardiac dysfunction in cancer patients undergoing anthracycline treatment.Oct 31, 2017

Pubmed Data : Free Radic Biol Med. 2017 Nov ;112:411-422. Epub 2017 Aug 30. PMID: 28838842
Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid
Diseases : Cancers: All, Cardiotoxicity: Chemotherapy-Induced
Pharmacological Actions : Antioxidants, Cardioprotective, Chemoprotective Agents

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