Central Nervous System Diseases

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34 Substances Researched for Central Nervous System Diseases
NameACCKFocus
Bacopa22Locked
Cannabis22Locked
Curcumin22Locked
Ginseng22Locked
Nigella sativa (aka Black Seed)22Locked
Ashwagandha11Locked
Ayahuasca11Locked
Bitter Melon11Locked
Cannabidiol11Locked
Carotenoids11Locked
Coffee11Locked
False Black Pepper11Locked
Fisetin11Locked
Ginger11Locked
Ginkgo biloba11Locked
Ginseng (Siberian)11Locked
Ginsenosides11Locked
Grapes11Locked
Green Tea11Locked
Hesperidin11Locked
Lichens11Locked
Luteolin11Locked
Lycopene11Locked
Olive Oil11Locked
Palmitoylethanolamide 11Locked
Perilla 11Locked
Red Sage11Locked
Rhodiola (Tibetan Ginseng)11Locked
Rosemary11Locked
Saffron11Locked
Salvia miltiorrhiza11Locked
Schisandra11Locked
Stigmasterol11Locked
Thymoquinone11Locked
4 Problem Substances Researched for Central Nervous System Diseases
NameACCKFocus
Aluminum13Locked
Mercury13Locked
Vaccine Adjuvants13Locked
Electronic Cigarettes12Locked
3 Problematic Actions Researched for Central Nervous System Diseases
NameACCKFocus
Vaccination: Influenza13Locked
Electromagnetic Field Harms11Locked
Electromagnetic Radiation11Locked

View the Evidence:
34 Abstracts with Central Nervous System Diseases Research

[+]

Central nervous system disease in patients with macrophagic myofasciitis.Apr 30, 2001

Pubmed Data : Brain. 2001 May ;124(Pt 5):974-83. PMID: 11335699
Article Published Date : Apr 30, 2001
Study Type : Human: Case Report
Additional Links
Diseases : Central Nervous System Diseases, Macrophagic myofasciitis
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

This report serves to document a case of CNS demyelination occurring 24h after influenza vaccination in a middle-aged patient.Aug 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Case Rep. 2014 Aug 31 ;15:368-73. Epub 2014 Aug 31. PMID: 25175754
Article Published Date : Aug 30, 2014
Study Type : Human: Case Report
Additional Links
Diseases : Central Nervous System Diseases, Vaccine-induced Toxicity
Additional Keywords : Central Nervous System Diseases, Influenza Vaccine, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Influenza
Problem Substances : Mercury
[+]

Exposure to e-cigarette aerosols poses a considerable risk to the developing central nervous system.Nov 16, 2017

Pubmed Data : Toxicol Sci. 2017 Nov 17. Epub 2017 Nov 17. PMID: 29161446
Article Published Date : Nov 16, 2017
Study Type : Animal Study
Additional Links
Diseases : Central Nervous System Diseases
Problem Substances : Electronic Cigarettes
[+]

Gut microbiome populations are associated with structure-specific changes in white matter architecture.Jan 09, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Psychiatry. 2018 01 10 ;8(1):6. Epub 2018 Jan 10. PMID: 29317592
Article Published Date : Jan 09, 2018
Study Type : Animal Study
Additional Links
Diseases : Central Nervous System Diseases, Dysbiosis
[+]

6-paradol effectively protects brain after cerebral ischemia, likely by attenuating neuroinflammation in microglia.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(3):e0120203. Epub 2015 Mar 19. PMID: 25789481
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Ginger
Diseases : Brain Inflammation , Central Nervous System Diseases, Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Paradols
[+]

A review for the pharmacological effect of lycopene in central nervous system disorders.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Mar ;111:791-801. Epub 2019 Jan 4. PMID: 30616078
Article Published Date : Feb 28, 2019
Study Type : Review
Additional Links
Substances : Carotenoids, Lycopene
Diseases : Alzheimer's Disease, Central Nervous System Diseases, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

A review of Schisandra chinensis and its phytotherapeutical applications.Dec 31, 2018

Pubmed Data : Ceska Slov Farm. 2019 ;68(3):95-118. PMID: 31431019
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Schisandra
Diseases : Cancers: All, Central Nervous System Diseases, Liver Damage
Pharmacological Actions : Chemotherapeutic, Hepatoprotective, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

A review of the benefits of hesperidin in central nervous system disorders.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Cell Biol. 2019 Dec ;52(4):369-377. Epub 2019 Dec 31. PMID: 31949974
Article Published Date : Nov 30, 2019
Study Type : Review
Additional Links
Substances : Hesperidin
Diseases : Central Nervous System Diseases, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Bacopa inhibits the release of inflammatory cytokines from microglial cells and inhibits enzymes associated with inflammation in the brain.Jul 25, 2016

Pubmed Data : J Ethnopharmacol. 2016 Jul 26. Epub 2016 Jul 26. PMID: 27473605
Article Published Date : Jul 25, 2016
Study Type : In Vitro Study
Additional Links
Substances : Bacopa
Diseases : Brain Inflammation , Central Nervous System Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cannabinoids have therapeutic potential in central nervous system disease. Jan 13, 2011

Pubmed Data : Eur J Pharmacol. 2011 Jan 13. Epub 2011 Jan 13. PMID: 12617697
Article Published Date : Jan 13, 2011
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabis
Diseases : Central Nervous System Diseases, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin-loaded nanoparticles: a novel therapeutic strategy in treatment of central nervous system disorders.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2019 ;14:4449-4460. Epub 2019 Jun 17. PMID: 31417253
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Epilepsy, Huntington Disease, Multiple Sclerosis, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Fisetin inhibits aggressive cell phenotypes by suppressing cell migration and proliferation.Feb 14, 2017

Pubmed Data : Int J Mol Med. 2017 Feb 15. Epub 2017 Feb 15. PMID: 28204814
Article Published Date : Feb 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Central Nervous System Diseases
Pharmacological Actions : Antiproliferative
[+]

Gastrodin promotes CNS myelination via a lncRNA Gm7237/miR-142a/MRF pathway.Dec 31, 2020

Pubmed Data : RNA Biol. 2021 09 ;18(9):1279-1290. Epub 2020 Nov 5. PMID: 33151124
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gastrodin
Diseases : Central Nervous System Diseases
Pharmacological Actions : MicroRNA modulator
Additional Keywords : Myelination
[+]

Ginseng and its constituents have potential merits in the treatment of cerebral disorders.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:2614742. Epub 2016 Aug 18. PMID: 27630732
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginseng, Ginsenosides
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Central Nervous System Diseases, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Lichen depsides and depsidones showed neuroactive properties in vitro, suggesting their potential to treat CNS disorders.Nov 14, 2016

Pubmed Data : Phytomedicine. 2016 Nov 15 ;23(12):1527-1534. Epub 2016 Aug 31. PMID: 27765373
Article Published Date : Nov 14, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lichens
Diseases : Central Nervous System Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain.Jul 09, 2017

Pubmed Data : Biomaterials. 2017 Jul 10 ;142:1-12. Epub 2017 Jul 10. PMID: 28715655
Article Published Date : Jul 09, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Brain Inflammation , Central Nervous System Diseases
Additional Keywords : Blood Brain Barrier, Exosomes
[+]

N. sativa seed exhibits beneficial effects in different central nervous system disorders including memory impairment, epilepsy, and neurotoxicity.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2015;2015:841823. Epub 2015 Oct 29. PMID: 26604923
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Central Nervous System Diseases, Epilepsy, Memory Disorders, Neurotoxicity
Pharmacological Actions : Neuroprotective Agents
[+]

Natural compounds are expected to serve as a potential therapeutic target for CNS injuries and diseases.Mar 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Mar 24 ;22(7). Epub 2021 Mar 24. PMID: 33804820
Article Published Date : Mar 23, 2021
Study Type : Review
Additional Links
Substances : Bitter Melon, Curcumin
Diseases : Central Nervous System Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective mechanisms of ginsenoside Rb1 in central nervous system diseases. Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:914352. Epub 2022 Jun 2. PMID: 35721176
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Ginsenosides
Diseases : Central Nervous System Diseases, Spinal Cord Injuries
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Autophagy Inhibitors, Neuroprotective Agents
[+]

Neuroprotective mechanisms of puerarin in central nervous system diseases.Jul 10, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Dis. 2022 Jul 11 ;13(4):1092-1105. Epub 2022 Jul 11. PMID: 35855345
Article Published Date : Jul 10, 2022
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Alzheimer's Disease, Central Nervous System Diseases, Cerebral Ischemia, Depression, Parkinson's Disease, Spinal Cord Injuries
Pharmacological Actions : Neuroprotective Agents
[+]

Nigella sativa and its components can be considered as promising agents in the treatment of nervous system disorders.Dec 31, 2015

Pubmed Data : Avicenna J Phytomed. 2016 Jan-Feb;6(1):104-16. PMID: 27247928
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Central Nervous System Diseases
[+]

Overview of Salvia miltiorrhiza as a potential therapeutic agent for various diseases.Sep 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Sep 13 ;9(9). Epub 2020 Sep 13. PMID: 32933217
Article Published Date : Sep 12, 2020
Study Type : Review
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Cancers: All, Cardiovascular Diseases, Central Nervous System Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Palmitoylethanolamide can be explored as a useful tool for preventing or treating the symptoms associated with neuroinflammation in CNS disorders.Mar 22, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Mar 23 ;7(1):375. Epub 2017 Mar 23. PMID: 28336953
Article Published Date : Mar 22, 2017
Study Type : In Vitro Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Brain Inflammation , Central Nervous System Diseases
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Plant derived phytocompound, embelin in CNS disorders: A systematic review.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:76. Epub 2017 Feb 27. PMID: 28289385
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : False Black Pepper
Diseases : Central Nervous System Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Radiofrequency electromagnetic felds can induce changes in the central nervous system.May 01, 2019

Pubmed Data : Biomol Ther (Seoul). 2019 May 1 ;27(3):265-275. PMID: 30481957
Article Published Date : May 01, 2019
Study Type : Review
Additional Links
Diseases : Central Nervous System Diseases
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
[+]

Stigmasterol promotes neuronal migration via reelin signaling in neurosphere migration assays.Nov 14, 2018

Pubmed Data : Nutr Neurosci. 2018 Nov 15:1-9. Epub 2018 Nov 15. PMID: 30433855
Article Published Date : Nov 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Stigmasterol
Diseases : Central Nervous System Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

The flavone luteolin improves central nervous system disorders by different mechanisms.Jul 31, 2018

Pubmed Data : J Mol Neurosci. 2018 Aug ;65(4):491-506. Epub 2018 Aug 6. PMID: 30083786
Article Published Date : Jul 31, 2018
Study Type : Review
Additional Links
Substances : Luteolin
Diseases : Central Nervous System Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

The present review considers the literature on the effects of botanicals on BDNF. Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Plast. 2017 ;2017:5965371. Epub 2017 Dec 31. PMID: 29464125
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Ashwagandha, Bacopa, Coffee, Ginkgo biloba, Ginseng, Ginseng (Siberian), Grapes, Green Tea, Olive Oil, Perilla , Red Sage, Rhodiola (Tibetan Ginseng), Saffron
Diseases : Central Nervous System Diseases
Pharmacological Actions : Brain-derived neurotrophic factor modulator
[+]

The role of lipids in the regulation of inflammation, pain and CNS diseases.Feb 15, 2017

Pubmed Data : Curr Med Chem. 2017 Feb 16. Epub 2017 Feb 16. PMID: 28215162
Article Published Date : Feb 15, 2017
Study Type : Review
Additional Links
Diseases : Anxiety, Autism, Central Nervous System Diseases, Irritable Bowel Syndrome, Neurodegenerative Diseases
Additional Keywords : Gut-brain Axis, Microbiota
[+]

The role of the gut microbiota in development, function and disorders of the central nervous system and the enteric nervous system.Apr 30, 2019

Pubmed Data : J Neuroendocrinol. 2019 May ;31(5):e12684. Epub 2019 Feb 1. PMID: 30614568
Article Published Date : Apr 30, 2019
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Autism Spectrum Disorders, Central Nervous System Diseases, Dysbiosis, Neurodegenerative Diseases, Parkinson's Disease, Schizophrenia
Additional Keywords : Gut-brain Axis
[+]

Therapeutic effects of rosemary and its active constituents on nervous system disorders.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2020 Sep ;23(9):1100-1112. PMID: 32963731
Article Published Date : Aug 31, 2020
Study Type : Review
Additional Links
Substances : Rosemary
Diseases : Central Nervous System Diseases
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Therapeutic potential of natural psychoactive drugs for central nervous system disorders: A perspective from polypharmacology.Dec 10, 2019

Pubmed Data : Curr Med Chem. 2019 Dec 11. Epub 2019 Dec 11. PMID: 31830883
Article Published Date : Dec 10, 2019
Study Type : Review
Additional Links
Substances : Ayahuasca, Cannabis
Diseases : Central Nervous System Diseases, Neurological Conditions, Psychiatric Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

This reviews the links between diet, gut dysbiosis, obesity, and immunologic and neurologic diseases.Feb 10, 2016

Pubmed Data : Curr Obes Rep. 2016 Feb 11. Epub 2016 Feb 11. PMID: 26865085
Article Published Date : Feb 10, 2016
Study Type : Review
Additional Links
Diseases : Central Nervous System Diseases, Dysbiosis, Neurodegenerative Diseases, Obesity
Additional Keywords : Gut-brain Axis
[+]

Wild Jujube: A review of its phytonutrients, health benefits, metabolism, and applications.Jun 21, 2022

Pubmed Data : J Agric Food Chem. 2022 Jun 22. Epub 2022 Jun 22. PMID: 35731918
Article Published Date : Jun 21, 2022
Study Type : Review
Additional Links
Substances : Jujube
Diseases : Central Nervous System Diseases, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

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