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Chemically-Induced Liver Damage
Views 3379
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337 Substances Researched for Chemically-Induced Liver Damage
Name
AC
CK
Focus
Curcumin
47
94
Polyphenols
12
23
Ginsenosides
12
22
Milk Thistle
2
22
Flavonoids
12
21
Nigella sativa (aka Black Seed)
9
18
Puerarin
9
16
Turmeric
8
16
Anthocyanins
7
14
Ginger
7
14
Melatonin
3
14
Resveratrol
7
14
Alpha-Lipoic Acid
6
12
Beet
6
12
Dandelion
6
12
Grape Seed Extract
6
12
Honey
6
12
Thymoquinone
6
12
Blueberry
5
10
Garlic
5
10
Honeysuckle
5
10
Lactobacillus plantarum
5
10
Reishi Mushroom
5
10
Turmeric: Fermented
1
10
Vitamin C
5
10
Vitamin E
5
10
Artichoke
5
9
Mangiferin
4
9
Pomegranate
5
9
Rose
5
9
Rosemary
5
9
Bael
4
8
Berberine
4
8
Camel Milk
4
8
Chlorella (Algae)
4
8
Chokeberry
4
8
Citrus naringin
5
8
Fermented Foods and Beverages
4
8
Jujube
4
8
Moringa oleifera
4
8
NAC (N-acetyl-L-cysteine)
5
8
Naringenin
4
8
Olive leaf extract
4
8
Quercetin
4
8
Selenium
4
8
Silymarin
4
8
Sweet Potato: Purple
4
8
White Tea
4
8
Caffeic acid phenethyl ester
4
7
EGCG (Epigallocatechin gallate)
4
7
Fucoidan
4
7
Ginkgo biloba
4
7
Radish
4
7
Bee Propolis
3
6
Black Tea
3
6
Blue Honeysuckle
3
6
Carrot
3
6
Catechin
3
6
Chlorogenic Acid
3
6
Diallyl sulfide
3
6
Diosmin
3
6
Ellagic Acid
3
6
Fenugreek
3
6
Geraniol
3
6
Green Tea
3
6
Hesperidin
3
6
Licorice
4
6
Luteolin
3
6
Lycopene
3
6
Mulberry
4
6
Olive Oil
3
6
Oregano
4
6
Royal Jelly
3
6
Sea buckthorn
3
6
Solanum nigrum (black nightshade)
3
6
Sulforaphane
4
6
Apple
3
5
Medicinal Mushrooms
3
5
Rooibos
3
5
Ursolic Acid
3
5
Acacia catechu
2
4
Apricot
2
4
Asiatic Acid
2
4
Ayurvedic formulation: Liv52
2
4
Bamboo
2
4
Beeswax
2
4
Berries: All
2
4
Burdock
2
4
Carvacrol
2
4
Chamomile
2
4
Chicory
2
4
Chrysin
2
4
Citrus Peel
2
4
Coenzyme Q10
2
4
Crocin
2
4
Dates
2
4
Dill
2
4
Embelia ribes
2
4
Flaxseed
2
4
Garden Cress (Lepidium sativum)
2
4
Garlic: Aged
2
4
Genistein
2
4
Guduchi
2
4
Henna
2
4
Hibiscus sabdariffa
2
4
Isoliquiritigenin
2
4
Lactobacillus casei
2
4
Lotus
3
4
Lychee
2
4
Myricetin
2
4
Nobiletin
2
4
Onion
2
4
Oyster Mushroom
2
4
Paeonol
2
4
Papaya
2
4
Passion Flower
2
4
Pomegranate Peel
2
4
Potato
2
4
Propolis: Bee
2
4
Raspberry ketone
2
4
Safflower
2
4
Sesamol
2
4
Shiitake Mushroom
2
4
Spirulina
2
4
Vitamin D
2
4
Walnut
2
4
Yeast
2
4
Yellow Tea
2
4
Zerumbone
2
4
Zinc
2
4
Barley
2
3
D-Limonene
2
3
Fig
2
3
Gallic Acid
2
3
Guava
2
3
Lactobacillus fermentum
2
3
Nutmeg
2
3
Oleanolic acid
2
3
Paeoniflorin
2
3
Thistle
2
3
Zataria multiflora
2
3
Ajwain
1
2
Almond
1
2
Aloe Vera
1
2
Andrographis
1
2
Angelica
1
2
Anise
1
2
Antrodia camphorata
1
2
Apigenin
2
2
Apocynin
1
2
Apple Cider Vinegar
1
2
Apple Polyphenols
1
2
Apples
1
2
Apricot Kernel
1
2
Artesunate
1
2
Ashwagandha
1
2
Astaxanthin
1
2
Banana Peel
1
2
Banana Stem
1
2
Barberry
1
2
Basil
1
2
Bee Pollen
1
2
Bee Venom
1
2
Berbamine
1
2
Beta Sitosterol
1
2
Betanin
1
2
Bilberry
1
2
Biochanin A
1
2
Bitter Apple
1
2
Bitter Melon
1
2
Bitter Orange
1
2
Black Currant
1
2
Black Raspberry
1
2
Broccoli Sprouts
1
2
Buckwheat
1
2
Butterbur
1
2
Caffeine
1
2
Capsaicin
1
2
Carnosic Acid
1
2
Celery
1
2
Celosia cristata (cockscomb)
1
2
Centella asiatica
1
2
Chickpea
1
2
Choline
1
2
Cinnamon
1
2
Cissus quadrangularis
1
2
Coconut Oil
1
2
Coconut Water
1
2
Coffee: Green/Unroasted
1
2
Cordyceps Militaris
1
2
Cordyceps sinensis
1
2
Cranberry
1
2
Crocetin
1
2
Cucurbitacin B
1
2
Cumin
1
2
Curcumol
1
2
DHA (Docosahexaenoic Acid)
1
2
Date Seeds
1
2
Dibenzoylmethane (DBM)
1
2
Earthworms
1
2
Echinacea
1
2
Eggplant
1
2
Eriodictyol
1
2
Eugenol
1
2
False Black Pepper
1
2
Fennel
1
2
Ferulic acid
1
2
Feverfew
1
2
Fisetin
1
2
Fish Oil
1
2
Folic Acid
1
2
Frankincense
1
2
Gingerol
1
2
Ginseng
1
2
Ginseng (Siberian)
1
2
Goat Milk
1
2
Gotu Kola
1
2
Grape
1
2
Graviola
1
2
Harmine
1
2
Holy Basil
1
2
Horehound
1
2
Hu Zhang (Polygonum cuspidatum)
1
2
Hydrogen Water
1
2
Hydroxytyrosol
1
2
Indian Mulberry
2
2
Indole-3-Carbinol
1
2
Isothiocyanates
1
2
Juniper
1
2
Kefir
1
2
Kombucha Tea
2
2
Lactobacillus probiotics
1
2
Lactobacillus salivarius
1
2
Lactoferrin
1
2
Lavender
2
2
Lignans
1
2
Ligustrazine
1
2
Liquiritigenin
1
2
Litchi
1
2
Lobelia
1
2
Long Pepper
1
2
Loquat
1
2
Loquat Seeds
1
2
Lutein
1
2
Mango
1
2
Miso
1
2
Modified Arabinoxylan Rice Bran (MGN-3)
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Myrica rubra
1
2
Nettle
1
2
Noni
1
2
Oak
1
2
Okra
1
2
Oleuropein
1
2
Olive
1
2
Orange
1
2
Oridonin
1
2
Orthosiphon
1
2
Palash
1
2
Palmitoylethanolamide
1
2
Panax Notoginseng
1
2
Pecan
1
2
Peppermint
1
2
Phellinus Linteus
1
2
Phosphatidylcholine
1
2
Pine Bark Extract
1
2
Piper cubeba (Cubeb)
1
2
Piperine
1
2
Plant Stem Cells
1
2
Plantago asiatica
1
2
Pomegranate Seed
1
2
Probiotics
1
2
Propolis: Brazillian
1
2
Prunella vulgaris
1
2
Pterocarpus marsupium
1
2
Pterostilbene
1
2
Pumpkin
1
2
Pumpkin Seed Oil/Meal
1
2
Rice: Brown
1
2
Rice: Parboiled
1
2
Rosmarinic acid
1
2
Saffron
1
2
Safranal
1
2
Saikosaponin
1
2
Schisandra
1
2
Seaweed
1
2
Sesame Seed Oil
1
2
Sesamin
1
2
Sessile Joyweed
1
2
Shikonin
1
2
Silibinin
1
2
Silica Hydride
1
2
Soy
1
2
Stevia
1
2
Strawberry
1
2
Tannic Acid
1
2
Taro
1
2
Taurine
1
2
Terminalia chebula
1
2
Thymol
1
2
Toona sinensis
1
2
Tyrosine
1
2
Urine
1
2
Urine: Cow
1
2
Vanillin
1
2
Verbascoside
1
2
Water: Electrolyzed Reduced
1
2
Watercress
1
2
Xanthohumol
1
2
Yoghurt
1
2
beta-Carotene
1
2
Agrimony
1
1
Allicin
1
1
Astragaloside
1
1
Astragalus
1
1
Blackberry
1
1
Caraway
1
1
Chaga Mushroom (Inonotus obliquus)
1
1
Clove
1
1
Coffee
1
1
Coriandor
1
1
Curcuminoids
1
1
Cyperus longus
1
1
Dong Quai
1
1
Gynostemma
1
1
Haritaki (Terminalia chebula)
1
1
Hydrangea
1
1
Motherwort
1
1
Mung Bean
1
1
Phyllanthus urinaria
1
1
Poria cocos
1
1
Punicalagin
1
1
Rice: Black
1
1
Sweet Potato
1
1
Tangeretin
1
1
Tetrahydrocurcumin
1
1
Water Mint
1
1
98 Problem Substances Researched for Chemically-Induced Liver Damage
Name
AC
CK
Focus
Statin Drugs
18
100
Acetaminophen
42
88
Paracetamol
39
71
Simvastatin
7
59
Atorvastatin
10
54
Bisphenol A
20
51
Pravastatin
4
43
Lovastatin
6
34
Cadmium
19
33
Fluvastatin
3
30
Isoniazid
3
30
Pesticides
12
23
Lead
10
20
High Fructose Corn Syrup
5
18
Rosuvastatin
4
17
Concanavalin A
9
16
Glyphosate
9
15
Mercury
5
13
Arsenic
7
12
Fluoroquinolone Antibiotic
2
12
Perfluorooctanoic acid (PFOA)
2
12
Tylenol
2
12
Tamoxifen
2
11
Aspartame
4
8
Dichloro-diphenyl-trichloroethane (DDT)
4
8
Tertiary butyl hydroperoxide
7
8
Electronic Cigarettes
4
7
Organophosphate Pesticides
4
7
Chlorpyrifos
3
6
Monosodium Glutamate (MSG)
3
6
Sodium Fluoride
3
6
Acrylamide
3
5
Paraquat
3
5
Aluminum
2
4
Arsenic Trioxide
2
4
Arsenite
2
4
Benzo(a)pyrene
2
4
Butylated Hydroxytoluene (BHT)
2
4
Cisplatin
2
4
Deltamethrin
2
4
Dichlorvos
2
4
Diclofenac
2
4
Fluoxetine (trade name Prozac)
2
4
Formaldehyde
2
4
Furan
2
4
Morphine
2
4
N-nitrosodiethylamine
2
4
Nanoparticles
2
4
Perfluorooctane sulfonate (PFOS)
2
4
Rosiglitazone (trade name Avandia)
2
4
Sucralose (aka Splenda)
2
4
Sugar Sweetened Beverages
2
4
Titanium Nanoparticles
2
4
Zinc Oxide
2
4
2-chlorobenzylidene malononitrile (CS)
1
3
Bisphenol S
2
3
Cerivastatin
1
3
Cholesterol Lowering Drugs
1
3
Fenofibrates
1
3
Quizalofop-P-ethyl
1
3
Triclosan
2
3
Benzene
1
2
Bisphenol F
1
2
Brilliant Blue FCF
1
2
Cobalt
1
2
Copper Oxide
1
2
Cypermethrin
1
2
Dexamethasone
1
2
Dichlorodiphenyldichloroethylene (DDE)
1
2
Erythrosine
1
2
Ethylene Glycol
1
2
FD&C Red #40
1
2
Fluoride
1
2
Food Colorings
1
2
Formaldehyde Releasers
1
2
Fructose
1
2
Glyphosate:Roundup
1
2
Levofloxacin
1
2
Metanil-Yellow Dye
1
2
N-nitrosodimethylamine
1
2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
1
2
Organochlorine pesticides
1
2
Organophosphates
1
2
Phthalates
1
2
Ponceau 4R (New Coccine)
1
2
Pyrethroid insecticide
1
2
Selective Serotonin Reuptake Inhibitors (SSRIs)
1
2
Silver
1
2
Sucrose
1
2
Tartrazine (Yellow Food Dye)
1
2
Thiazolidinediones
1
2
Titanium Dioxide
1
2
Toluene
1
2
Zoledronic Acid
1
2
Dimethoate
1
1
Parabens
1
1
Polychlorinated biphenyls (PCBs)
1
1
Zineb
1
1
1 Therapeutic Actions Researched for Chemically-Induced Liver Damage
Name
AC
CK
Focus
Exercise: Aerobic
1
2
1 Problematic Actions Researched for Chemically-Induced Liver Damage
Name
AC
CK
Focus
Western Diet
1
2
Research Articles
721
Cumulative Knowledge Score
1166
Overall Research Rating
EXCELLENT
Related Topics
Chemically-Induced Liver Damage is a Sub of the following Topic
Liver Damage
View the Evidence:
964 Abstracts with Chemically-Induced Liver Damage Research
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[+]
Prophylactic therapy of milk thistle on anti-tuberculosis drug-induced liver injury.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Can J Gastroenterol Hepatol. 2019 ;2019:3192351. Epub 2019 Jan 10. PMID:
30733935
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Milk Thistle
Diseases
:
Chemically-Induced Liver Damage
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
The use of statins for LDL suppression is associated with increased risk for cancer.
Jul 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2007 Jul 31 ;50(5):409-18. Epub 2007 Jul 16. PMID:
17662392
Article Published Date
: Jul 31, 2007
Study Type
: Meta Analysis
Additional Links
Diseases
:
Cancers: All
,
Chemically-Induced Liver Damage
,
High Cholesterol
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
,
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Association of lifetime exposure to glyphosate and aminomethylphosphonic acid with liver inflammation and metabolic syndrome at young adulthood.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Health Perspect. 2023 Mar ;131(3):37001. Epub 2023 Mar 1. PMID:
36856429
Article Published Date
: Feb 28, 2023
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Metabolic Syndrome X
Additional Keywords
:
Risk Factors
Problem Substances
:
Glyphosate
,
Pesticides
[+]
Atorvastatin-induced acute pancreatitis has been reported.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Pharmacother. 2011 Jan ;2(1):40-2. PMID:
21701646
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Pancreatitis
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Autoimmune hepatitis associated with atorvastatin use has been reported.
Aug 01, 2003
Click here to read the entire abstract
Pubmed Data
: Eur J Gastroenterol Hepatol. 2003 Aug ;15(8):921-4. PMID:
12867804
Article Published Date
: Aug 01, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Autoimmune
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Bisphenol A was detected above the detection limit in all samples in individuals affected by non-alcoholic fatty liver disease.
Jun 04, 2017
Click here to read the entire abstract
Pubmed Data
: J Pharm Biomed Anal. 2017 Jun 5 ;140:105-112. Epub 2017 Mar 10. PMID:
28346880
Article Published Date
: Jun 04, 2017
Study Type
: Human In Vitro, Human Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Additional Keywords
:
Bisphenol A
,
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
[+]
Combined treatment including melatonin resulted in the improvement of general conditions in 81.7% of the patients
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Klin Med (Mosk). 2013 ;91(3):50-3. PMID:
23789453
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
Diseases
:
Chemically-Induced Liver Damage
Additional Keywords
:
Plant Extracts
[+]
Drug-induced liver toxicity (particularly acetaminophen-induced liver toxicity) has replaced viral hepatitis as the most single frequent cause of acute liver failutre in ubran
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Z Gastroenterol. 2009 Sep;47(9):807-13. Epub 2009 Sep 11. PMID:
19750427
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Tylenol
[+]
Exposure of children to even low doses of BPA may adversely affect later liver function.
Nov 16, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Res. 2017 Nov 17 ;161:195-201. Epub 2017 Nov 17. PMID:
29156342
Article Published Date
: Nov 16, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
[+]
Fermented turmeric powder is well-tolerated and effective in subjects with elevated alanine transaminase levels.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2013 ;13:58. Epub 2013 Mar 8. PMID:
23497020
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Turmeric: Fermented
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
Fluoroquinolone therapy and idiosyncratic acute liver injury: a population-based study.
Aug 12, 2012
Click here to read the entire abstract
Pubmed Data
: CMAJ. 2012 Aug 13. Epub 2012 Aug 13. PMID:
22891208
Article Published Date
: Aug 12, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Fluoroquinolone Antibiotic
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Fluvastatin has been linked to adverse hepatic reactions.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Drug Saf. 2006 ;29(12):1163-72. PMID:
17147462
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Nutrient Depletion: Statin Drugs
Problem Substances
:
Fluvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Med Hypotheses. 2019 Mar ;124:40-41. Epub 2019 Feb 4. PMID:
30798914
Article Published Date
: Feb 28, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Problem Substances
:
High Fructose Corn Syrup
[+]
Isoniazid has been associated with grade 3 or 4 liver failure in 1.4%-5.2% of patients being treated for latent tuberculosis infection.
Dec 15, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Infect Dis. 2009 Dec 15;49(12):1883-9. PMID:
19911936
Article Published Date
: Dec 15, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Problem Substances
:
Isoniazid
[+]
Isoniazid treatment in latent tuberculosis infection may be associated with moderate-to-severe liver damage without symptoms.
Jul 01, 2005
Click here to read the entire abstract
Pubmed Data
: Chest. 2005 Jul;128(1):116-23. PMID:
16002924
Article Published Date
: Jul 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Isoniazid
[+]
Liver failure and damage are rare but severe unintended consequences of statin drug use.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Hepatol. 2011 Aug 31. Epub 2011 Aug 31. PMID:
21889469
Article Published Date
: Aug 31, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage
,
Liver Disease
,
Liver Failure: Drug Induced
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Fluvastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
More than half of patients who present at the hospital with acetaminophen-induced liver damage or liver failure have undetectable levels of acetaminophen.
Feb 04, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Gastroenterol Hepatol. 2019 Feb 5. Epub 2019 Feb 5. PMID:
30731196
Article Published Date
: Feb 04, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
[+]
Perfluorooctanoic acid has hepatotoxic effects.
Jul 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Health Perspect. 2016 Aug ;124(8):1227-33. Epub 2016 Mar 15. PMID:
26978841
Article Published Date
: Jul 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Perfluorinated Compound Toxicity
Problem Substances
:
Perfluorooctanoic acid (PFOA)
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Severe liver toxicity requiring discontinuation occurs in 5% of simvastatin-treated patients and 4.5% of pravastatin-treated patients.
Jan 01, 1992
Click here to read the entire abstract
Pubmed Data
: Minerva Gastroenterol Dietol. 1992 Jan-Mar;38(1):41-4. PMID:
1520752
Article Published Date
: Jan 01, 1992
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Statin-Induced Pathologies
Problem Substances
:
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Severe, even fatal liver injuries have resulted as a consequence of isoniazid treatment in individuals with latent tuberculosis.
Mar 05, 2010
Click here to read the entire abstract
Pubmed Data
: MMWR Morb Mortal Wkly Rep. 2010 Mar 5;59(8):224-9. PMID:
20203555
Article Published Date
: Mar 05, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Isoniazid
[+]
Tamoxifen treatment for breast cancer may result in fatty liver.
Nov 01, 2000
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2000 Nov-Dec;7(6):1299-304. PMID:
11032933
Article Published Date
: Nov 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
Additional Keywords
:
Drug: 5-flourouracil
,
Drug: Doxorubicin
,
Drug: Tamoxifen
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Unintended consequences of statin drug use are increased risk of esophageal cancer, kidney failure, cataract, liver dysfunction and myopathies.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: BMJ. 2010;340:c2197. Epub 2010 May 20. PMID:
20488911
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Cardiovascular Diseases
,
Cataract
,
Chemically-Induced Liver Damage
,
Esophageal Cancer
,
Kidney Failure
,
Myopathies
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Fluvastatin
,
Pravastatin
,
Rosuvastatin
,
Simvastatin
,
Statin Drugs
[+]
Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue.
Aug 11, 2019
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2019 Aug 12. Epub 2019 Aug 12. PMID:
31403256
Article Published Date
: Aug 11, 2019
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
[+]
Curcumin could modulate hepatocyte epithelial-mesenchymal transition implicated in treatment of liver fibrosis.
Aug 23, 2015
Click here to read the entire abstract
Pubmed Data
: Lab Invest. 2015 Aug 24. Epub 2015 Aug 24. PMID:
26302188
Article Published Date
: Aug 23, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2017 Feb ;32(2):630-644. Epub 2016 Mar 28. PMID:
28071871
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Mangiferin
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Methylmercury
Problem Substances
:
Mercury
[+]
Procyanidin B2 alleviates palmitic acid-Induced injury in HepG2 cells.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:8920757. Epub 2021 Dec 16. PMID:
34956386
Article Published Date
: Dec 31, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Procyanidin B2
Diseases
:
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
A case of hepatitis caused by simvastatin has been reported.
Jan 01, 1991
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Clin Biol. 1991 ;15(1):94-5. PMID:
2010080
Article Published Date
: Jan 01, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
,
Simvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis associated with atorvastatin use has been reported.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Hepatol. 2006 Jan ;29(1):21-4. PMID:
16393626
Article Published Date
: Jan 01, 2006
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis associated with pravastatin has been reported.
May 01, 1999
Click here to read the entire abstract
Pubmed Data
: Am J Gastroenterol. 1999 May ;94(5):1388-90. PMID:
10235223
Article Published Date
: May 01, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Pravastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis induced by cerivastatin has been reported.
May 18, 2002
Click here to read the entire abstract
Pubmed Data
: Med Clin (Barc). 2002 May 18 ;118(18):717. PMID:
12042141
Article Published Date
: May 18, 2002
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Cerivastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis induced by fenofibrate has been reported.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Clin Pharm Ther. 2009 Oct;34(5):599-602. PMID:
19744016
Article Published Date
: Oct 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity
,
Hepatitis
Problem Substances
:
Fenofibrates
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute exposure to CS tear gas has been reported to cause several health problems in an individual.
Dec 26, 1981
Click here to read the entire abstract
Pubmed Data
: Schweiz Med Wochenschr. 1981 Dec 26 ;111(52):2056-60. PMID:
6800031
Article Published Date
: Dec 26, 1981
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Heart Failure
,
Liver Damage
,
Pneumonia
Problem Substances
:
2-chlorobenzylidene malononitrile (CS)
[+]
Acute hepatitis induced by lovastatin has been reported.
Sep 01, 1994
Click here to read the entire abstract
Pubmed Data
: Dig Dis Sci. 1994 Sep ;39(9):2032-3. PMID:
8082513
Article Published Date
: Sep 01, 1994
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Atorvastatin has been reported to have caused severe acute hepatitis with symptomatic cholestasis for more than 3 months and bile duct injury.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Acta Gastroenterol Belg. 2008 Jul-Sep;71(3):318-20. PMID:
19198578
Article Published Date
: Jul 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Bile Duct Injury
,
Chemically-Induced Liver Damage
,
Cholestasis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Atorvastatin-induced cholestatic hepatitis in a young woman with systemic lupus erythematosus has been reported.
Aug 09, 1999
Click here to read the entire abstract
Pubmed Data
: Arch Intern Med. 1999 Aug 9-23;159(15):1811-2. PMID:
10448788
Article Published Date
: Aug 09, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Cholestatic jaundice induced by atorvastatin has been observed.
Jul 01, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Isr Med Assoc J. 2009 Jul ;11(7):440-1. PMID:
19911499
Article Published Date
: Jul 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Autoimmune Diseases
,
Chemically-Induced Liver Damage
,
Hepatitis: Cholestatic
,
Jaundice
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Ginsenoside Rg1 protects mice against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced liver injury.
May 16, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ethnopharmacol. 2022 May 17 ;294:115394. Epub 2022 May 17. PMID:
35595219
Article Published Date
: May 16, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Hepatitis associated with treatment with lovastatin has been reported.
Mar 01, 1998
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Hepatol. 1998 Mar ;21(3):127-8. PMID:
9607293
Article Published Date
: Mar 01, 1998
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Liver fibrosis has been attributed to lipid lowering medications.
Sep 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Intern Med. 2001 Sep ;250(3):249-54. PMID:
11555130
Article Published Date
: Sep 01, 2001
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Cholesterol Lowering Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Lovastatin monotherapy has been reported to have been a cause of rhabdomyolysis, acute renal failure and hepatopathy.
Jul 01, 1997
Click here to read the entire abstract
Pubmed Data
: Jpn Heart J. 1997 Jul ;38(4):541-5. PMID:
9350151
Article Published Date
: Jul 01, 1997
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Failure: Acute
,
Rhabdomyolysis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Nephrotoxic
[+]
Mixed cholestatic/hepatocellular liver injury induced by the herbicide quizalofop-p-ethyl has been reported.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Environ Health Perspect. 2007 Oct ;115(10):1479-81. PMID:
17938739
Article Published Date
: Oct 01, 2007
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
Problem Substances
:
Quizalofop-P-ethyl
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Reversible acute hepatitis induced by rosuvastatin has been reported.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: South Med J. 2008 Jul ;101(7):768. PMID:
19209117
Article Published Date
: Jul 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Statin-Induced Pathologies
Problem Substances
:
Rosuvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Rosmarinic acid exerts anti-inflammatory effect and relieves oxidative stress via Nrf2 activation in carbon tetrachloride-induced liver damage.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2022 ;66. Epub 2022 Nov 18. PMID:
36590857
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Rosmarinic acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Rosuvastatin-associated hepatitis with autoimmune features has been reported.
May 01, 2005
Click here to read the entire abstract
Pubmed Data
: Eur J Gastroenterol Hepatol. 2005 May ;17(5):589-90. PMID:
15827453
Article Published Date
: May 01, 2005
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Autoimmune
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Rosuvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Simvastatin has been reported to cause cholestatic hepatitis.
Apr 01, 1991
Click here to read the entire abstract
Pubmed Data
: Recenti Prog Med. 1991 Apr ;82(4):233-5. PMID:
1857844
Article Published Date
: Apr 01, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Elevated: ALT
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Simvastatin has been reported to cause liver lesions.
Apr 13, 1996
Click here to read the entire abstract
Pubmed Data
: Ned Tijdschr Geneeskd. 1996 Apr 13 ;140(15):846-8. PMID:
8668280
Article Published Date
: Apr 13, 1996
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Jaundice
,
Liver Damage
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
[+]
Virgin coconut oil complements with its polyphenol components mitigate sodium fluoride toxicity in vitro and in vivo.
Aug 17, 2021
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2021 Aug 18:1-7. Epub 2021 Aug 18. PMID:
34407699
Article Published Date
: Aug 17, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Coconut Oil
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
,
Fluoride Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Sodium Fluoride
[+]
Alleviative effect of lactoferrin interventions against the hepatotoxicity induced by titanium dioxide nanoparticles.
May 15, 2023
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2023 May 16. Epub 2023 May 16. PMID:
37191759
Article Published Date
: May 15, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Chemically-Induced Liver Damage
,
Titanium Toxicity
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Titanium Dioxide
,
Titanium Nanoparticles
[+]
The protective effect of chrysin against carbon tetrachloride-induced kidney and liver tissue damage.
Apr 29, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2020 Apr 30:1-12. Epub 2020 Apr 30. PMID:
32349632
Article Published Date
: Apr 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
[+]
"Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury."
Oct 01, 2012
Click here to read the entire abstract
Pubmed Data
: Toxicol Lett. 2012 Oct 2 ;214(1):9-18. Epub 2012 Aug 10. PMID:
22902350
Article Published Date
: Oct 01, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Chimera
[+]
"Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats."
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2006 Oct ;290(1-2):61-7. Epub 2006 Aug 26. PMID:
16937016
Article Published Date
: Oct 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Chemically-Induced Liver Damage
,
Formaldehyde Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Formaldehyde
[+]
6-gingerol, a major ingredient of ginger attenuates diethylnitrosamine-induced liver injury.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2021 ;2021:6661937. Epub 2021 Jan 19. PMID:
33531877
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
6-Shogaol alleviates CCl4-induced liver fibrosis by attenuating inflammatory response.
Apr 27, 2022
Click here to read the entire abstract
Pubmed Data
: Acta Biochim Pol. 2022 Apr 28 ;69(2):363-370. PMID:
35485077
Article Published Date
: Apr 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
A comparative study on the hepatoprotective effect of selenium-nanoparticles and dates flesh extract on carbon tetrachloride induced liver damage.
Sep 11, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Anat Cell Biol. 2023 Sep 12. Epub 2023 Sep 12. PMID:
37696756
Article Published Date
: Sep 11, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Selenium
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A curcumin-phospholipid complex works synergistically to protect the livers of rats following chemical exposure.
Feb 07, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Pharm. 2007 Feb 7;330(1-2):155-63. Epub 2006 Sep 23. PMID:
17112692
Article Published Date
: Feb 07, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Phosphatidylcholine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A quantitative study on the protective effects of resveratrol against bisphenol A-induced hepatotoxicity.
Apr 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Med Sci. 2021 May ;46(3):218-227. PMID:
34083854
Article Published Date
: Apr 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Bisphenol A
[+]
A standardized pomegranate fruit extract ameliorates thioacetamide-induced liver fibrosis.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2023 Mar ;9(3):e14256. Epub 2023 Mar 4. PMID:
36938469
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
[+]
A water extract of the leaves of Z. jujuba is efficacious for prevention and treatment of carbon tetrachloride induced hepatic injury in mice.
Feb 21, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 Feb 22 ;8(2):816-822. PMID:
28124048
Article Published Date
: Feb 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Jujube
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A. cerana honey can prevent bromobenzene-induced hepatic damage in mice.
Jan 15, 2018
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2018 Jan 16. Epub 2018 Jan 16. PMID:
29337369
Article Published Date
: Jan 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A. lappa could protect the liver cells from carbon tetrachloride or acetaminophen-induced liver damages.
Dec 31, 1999
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2000 ;28(2):163-73. PMID:
10999435
Article Published Date
: Dec 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Burdock
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
A. marmelos attenuates carbon tetrachloride-mediated hepatic oxidative stress, toxicity, tumor promotion.
Mar 31, 2009
Click here to read the entire abstract
Pubmed Data
: J Enzyme Inhib Med Chem. 2009 Apr ;24(2):320-7. PMID:
18830880
Article Published Date
: Mar 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
A. sessilis has hepatoprotective activity against carbon tetrachloride liver damage.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Indian J Clin Biochem. 2018 Apr ;33(2):190-195. Epub 2017 May 18. PMID:
29651210
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Sessile Joyweed
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Acacia catechu extract affords hepato-protection against DMBA in rats through modulation of phase I, II and anti-oxidative enzymes.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(2):e90083. Epub 2014 Feb 27. PMID:
24587216
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Acacia catechu
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Phase I Detoxification Enzyme Inducer
,
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Plant Extracts
[+]
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID:
29128856
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Aegle marmelos methanol extract could protect against carbon tetrachloride.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Rep. 2018 ;5:1161-1168. Epub 2018 Oct 13. PMID:
30627516
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Aerobic exercise and eugenol supplementation ameliorated liver injury induced by chlorpyrifos.
Feb 24, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2020 Feb 25. Epub 2020 Feb 25. PMID:
32096903
Article Published Date
: Feb 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Eugenol
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Chlorpyrifos
[+]
Aged garlic extract prevents alcohol-induced cytotoxicity.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2023 May ;67(10):e2200627. Epub 2023 Mar 23. PMID:
36856009
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
[+]
Aged garlic extract supplementation could be used to reverse the hepatic injury following ethephon exposure through its antioxidant capacity.
Dec 20, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2019 Dec 21. Epub 2019 Dec 21. PMID:
31865585
Article Published Date
: Dec 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Ajwain attenuates chemically-induced liver damage in rats.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2009 Feb;47(2):279-82. Epub 2008 Oct 4. PMID:
18940228
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ajwain
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Alkaloidal extract from Carica papaya seeds ameliorates CCl 4-induced hepatocellular carcinoma.
Jul 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2021 Aug ;7(8):e07849. Epub 2021 Aug 20. PMID:
34471716
Article Published Date
: Jul 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Papaya
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Almond skin extract has hepatoprotective properties against chemically-induced liver cell damage.
Apr 29, 2010
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Apr 29;185(2):101-9. Epub 2010 Mar 6. PMID:
20211157
Article Published Date
: Apr 29, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Almond
,
Catechin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Alpha lipoic acid possess protective effects against chlorpyrifos induced liver injury.
Feb 22, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2018 Feb 23 ;59:17-23. Epub 2018 Feb 23. PMID:
29500983
Article Published Date
: Feb 22, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Chlorpyrifos
,
Pesticides
[+]
Alpha-lipoic acid alleviated fluoride-induced hepatocyte injury.
Dec 20, 2022
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2022 Dec 21 ;70(50):15962-15971. Epub 2022 Dec 2. PMID:
36459405
Article Published Date
: Dec 20, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Fluoride
[+]
Alpha-lipoic acid ameliorates sodium valproate-induced liver injury.
Apr 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Vet World. 2020 May ;13(5):963-966. Epub 2020 May 22. PMID:
32636594
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Alpha-lipoic acid could prevent from mitochondria dysfunction.
Apr 16, 2021
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2021 Apr 17. Epub 2021 Apr 17. PMID:
33866498
Article Published Date
: Apr 16, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Arsenic
[+]
Alpha-lipoic acid protected against valproic acid-induced liver damage and hematological disturbance.
Dec 03, 2020
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2020 Dec 4. Epub 2020 Dec 4. PMID:
33275538
Article Published Date
: Dec 03, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha-Lipoic acid protects against microcystin-LR induced hepatotoxicity through regeneration of glutathione via activation of Nrf2
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2020 Jul ;35(7):738-746. Epub 2020 Feb 15. PMID:
32061150
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
[+]
Amelioration of cyclophosphamide-induced DNA damage, oxidative stress, and hepato- and neurotoxicity by Piper longum extract.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1147823. Epub 2023 Mar 10. PMID:
36969834
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Long Pepper
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Hepatoprotective
[+]
Ameliorative effect of betanin on experimental cisplatin-induced liver injury.
Mar 03, 2021
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2021 Mar 4:e22753. Epub 2021 Mar 4. PMID:
33661552
Article Published Date
: Mar 03, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Betanin
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Ameliorative effect of N-acetylcysteine against glyphosate-induced hepatotoxicity.
Apr 01, 2021
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2021 Apr 2. Epub 2021 Apr 2. PMID:
33797725
Article Published Date
: Apr 01, 2021
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Chemically-Induced Liver Damage
,
Glyphosate Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Glyphosate
[+]
Ameliorative effects of honey, propolis, pollen, and royal jelly mixture against chronic toxicity of sumithion insecticide.
Jun 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Jun 5 ;25(11). Epub 2020 Jun 5. PMID:
32517066
Article Published Date
: Jun 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Bee Pollen
,
Bee Propolis
,
Honey
,
Royal Jelly
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Pesticides
[+]
Ameliorative effects of Moringa oleifera leaf extract on levofloxacin-induced hepatic toxicity.
Feb 19, 2019
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2019 Feb 20:1-7. Epub 2019 Feb 20. PMID:
30782023
Article Published Date
: Feb 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Antibiotic Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-10 upregulation
Problem Substances
:
Fluoroquinolone Antibiotic
,
Levofloxacin
[+]
Ameliorative effects of propolis and royal jelly against CCl4 -induced hepatotoxicity and nephrotoxicity.
Nov 22, 2022
Click here to read the entire abstract
Pubmed Data
: Chem Biodivers. 2022 Nov 23:e202200948. Epub 2022 Nov 23. PMID:
36416002
Article Published Date
: Nov 22, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Bee
,
Royal Jelly
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Renoprotective
[+]
Ameliorative or corrective effects of Fig " Ficus carica" extract on nickel-induced hepatotoxicity.
Jun 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Res. 2022 Jul ;38(3):311-321. Epub 2022 Jan 18. PMID:
35874505
Article Published Date
: Jun 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Fig
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Amygdalin ameliorates liver fibrosis through inhibiting activation of TGF-β/Smad signaling.
Mar 31, 2023
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2023 Apr ;29(4):316-324. Epub 2021 Nov 24. PMID:
34816365
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Amygdalin protects against acetaminophen-induced acute liver failure.
Apr 29, 2022
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2022 Apr 30 ;602:105-112. Epub 2022 Mar 3. PMID:
35259588
Article Published Date
: Apr 29, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
An anthocyanin-rich extract of Hibiscus sabdariffa calyces had hepatoprotective activity.
Aug 25, 2016
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2016 Aug 26:1-10. Epub 2016 Aug 26. PMID:
27564372
Article Published Date
: Aug 25, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Hibiscus sabdariffa
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
An extract of P. guajava leaves and its isolated quercetin fraction have a hypolipidemic activity against carbon tetrachloride induced hepatotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacogn Mag. 2018 Jan-Mar;14(53):4-8. Epub 2018 Feb 20. PMID:
29576694
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Guava
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
An extract of P. vulgaris alleviated carbon tetrachloride-induced hepatic in vivo.
Oct 12, 2015
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2015 Oct 13. Epub 2015 Oct 13. PMID:
26460672
Article Published Date
: Oct 12, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Prunella vulgaris
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-4 downregulation
,
Interleukin-8 downregulation
,
MicroRNA modulator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An isoflavonoid from seeds of Lepidium sativum L. has a protective effect on hepatotoxicity induced by paracetamol.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2014 ;19(10):15440-51. Epub 2014 Sep 26. PMID:
25264831
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Garden Cress (Lepidium sativum)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
An unexpected role of cholesterol sulfotransferase and its regulation in sensitizing mice to acetaminophen induced liver injury.
Apr 02, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Pharmacol. 2019 Apr 3. Epub 2019 Apr 3. PMID:
30944208
Article Published Date
: Apr 02, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Andrographis paniculata ameliorates carbon tetrachloride (CCl(4))-dependent hepatic damage and toxicity.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Rep. 2011 ;16(3):134-43. PMID:
21801496
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Andrographis paniculata leaf extract prevents thioacetamide-induced liver cirrhosis in rats.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(10):e109424. Epub 2014 Oct 3. PMID:
25280007
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Andrographolide, a compound found within andrographis, has anti-tumor activity in chemically-induced liver damage.
Jun 01, 2005
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2005 Jun;21(6):756-61. PMID:
19679627
Article Published Date
: Jun 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2018 May ;111:1133-1139. Epub 2018 Feb 19. PMID:
29415408
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Angelica sinensis pretreatment could effectively guard the liver and kidney of mice from D-galactose-induced injury.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Sep ;21(9):887-898. Epub 2018 Aug 15. PMID:
30109956
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Angelica
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Kidney Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Renoprotective
[+]
Anise seed possesses protective effects against carbon tetrachloride (CCl4)-induced toxicity.
Jan 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2015 Feb ;18(2):205-11. PMID:
25825639
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Anise
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Essential Oils
[+]
Anthocyanin-rich black currant extract affords chemoprevention against chemically-induced liver cancer in rats.
Jan 07, 2011
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2011 Jan 7. Epub 2011 Jan 7. PMID:
21216582
Article Published Date
: Jan 07, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Black Currant
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Bax/Bcl2 ratio: Increase
,
Chemopreventive
[+]
Anthocyanins from bilberry extract have strong antioxidant properties and therefore can be considered as powerful hepatoprotectives in natural products.
Jul 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jul 15 ;157:168-77. Epub 2016 Jun 14. PMID:
27312419
Article Published Date
: Jul 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins isolated from blueberry ameliorates carbon tetrachloride induced liver fibrosis.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Oct ;120:491-499. Epub 2018 Jul 27. PMID:
30056145
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Anti-hepatitic activity of ginsenoside Ro.
Nov 30, 1991
Click here to read the entire abstract
Pubmed Data
: Planta Med. 1991 Dec ;57(6):523-6. PMID:
1818342
Article Published Date
: Nov 30, 1991
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Anti-inflammatory, anti-apoptotic, and antioxidant actions of Middle Eastern Phoenix dactylifera extract on mercury-induced hepatotoxicity in vivo.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2020 Aug ;47(8):6053-6065. Epub 2020 Jul 31. PMID:
32737827
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Mercury
[+]
Antioxidant and hepato-preventive effect of Citrus aurantium extract against carbon tetrachloride-induced hepatotoxicity.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Arch Physiol Biochem. 2019 Oct ;125(4):332-343. Epub 2018 Apr 17. PMID:
29663826
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Antioxidant and hepatoprotective potential of Lawsonia inermis L. leaves against 2-acetylaminofluorene induced hepatic damage.
Jan 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Jan 18 ;17(1):56. Epub 2017 Jan 18. PMID:
28100199
Article Published Date
: Jan 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Henna
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Antioxidant and protective effects of extra virgin olive oil incorporated with diallyl sulfide against CCl 4-induced acute liver injury.
Nov 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Sci Nutr. 2021 Dec ;9(12):6818-6830. Epub 2021 Oct 25. PMID:
34925810
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Diallyl sulfide
,
Olive Oil
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
antioxidant effect of thymoquinone could protect damage of liver parameters against morphine toxicity.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Prev Med. 2018 ;9:8. Epub 2018 Jan 29. PMID:
29441185
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Morphine
[+]
Antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrate gum resin in CCl4-induced hepatotoxicity
Jan 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2020 Feb ;19(2):1313-1321. Epub 2019 Dec 19. PMID:
32010304
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antioxidative, anti-inflammatory and anti-apoptotic action of ellagic acid against lead acetate induced testicular and hepato-renal oxidative damages.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2022 Jun 1 ;302:119048. Epub 2022 Feb 24. PMID:
35219795
Article Published Date
: May 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
,
Oxidative Stress
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
Problem Substances
:
Lead
[+]
Apigenin protects from hepatorenal damage caused by lead acetate.
Dec 21, 2022
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2022 Dec 22:e23275. Epub 2022 Dec 22. PMID:
36550699
Article Published Date
: Dec 21, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
,
Lead Poisoning
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Lead
[+]
Apocynin prevented inflammation and oxidative stress in carbon tetra chloride induced hepatic dysfunction in rats.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Aug ;92:421-428. Epub 2017 May 27. PMID:
28558355
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apocynin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Apple cider vinegar could be promising for attenuation of liver cell damages induced by several toxins through its powerful antioxidant properties.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microsc Ultrastruct. 2020 Jul-Sep;8(3):126-131. Epub 2020 Sep 10. PMID:
33282688
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Apple Cider Vinegar
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Mercury
[+]
Apricot (Prunus armeniaca L.) has a protective effect against fatty liver and damage induced by carbon tetrachloride in Wistar rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Dec;102(12):1767-75. PMID:
19822030
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Apricot supplementation and irradiation given in combination, offer maximum protection against DMBA-induced hepatic carcinogenesis.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Aug ;70:128-33. Epub 2014 May 10. PMID:
24819963
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy and Radiation Toxicity
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
[+]
Aqueous extracts of C. papaya may be useful in preventing carbon tetrachloride and acetaminophen induced liver toxicities.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Intercult Ethnopharmacol. 2016 Jan-Feb;5(1):27-35. Epub 2016 Jan 27. PMID:
27069723
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Papaya
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Aqueous extracts of leaves of R. sativus offer partial protection against hepatotoxicity induced by carbon tetrachloride.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Afr J Tradit Complement Altern Med. 2014 ;11(3):102-6. Epub 2014 Apr 3. PMID:
25371570
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Radish
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Aqueous extracts of Rosa damascene may prevent hepatic damage from acetaminophen induced toxicity in rats.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Environ Pathol Toxicol Oncol. 2012 ;31(3):193-201. PMID:
23339694
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Rose
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Arctium lappa root extract prevents lead-induced liver injury.
Nov 23, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2019 Nov 24 ;8(12). Epub 2019 Nov 24. PMID:
31771282
Article Published Date
: Nov 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Burdock
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Lead
[+]
Artichoke extract ameliorates carbon tetrachloride-induced liver damage and oxidative stress in rats.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2008 Sep;60(6):475-80. Epub 2008 Jun 25. PMID:
18583118
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
[+]
Artichoke leaf extract has liver protective effects and causes downregulation of oxidative stress in acute diazinon-induced liver injury.
Aug 29, 2019
Click here to read the entire abstract
Pubmed Data
: J Basic Clin Physiol Pharmacol. 2019 Aug 30 ;30(5). Epub 2019 Aug 30. PMID:
31469651
Article Published Date
: Aug 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Organophosphate Pesticides
[+]
Artichoke leaf extract may be used as a pharmaceutical phytomedicine in the treatment of liver diseases.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Springerplus. 2016 ;5:216. Epub 2016 Feb 29. PMID:
27026910
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Artificial sweeteners cause cytoplasmic fatty change of varying degrees.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Coll Physicians Surg Pak. 2019 Sep ;29(9):848-851. PMID:
31455480
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
Problem Substances
:
Aspartame
,
Sucralose (aka Splenda)
[+]
Assessment of hepatoprotective effect of chokeberry juice in tats treated chronically with carbon tetrachloride.
Mar 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Mar 11 ;25(6). Epub 2020 Mar 11. PMID:
32168847
Article Published Date
: Mar 10, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Assessment of the phytochemical profile, antioxidant capacity, and hepatoprotective effect of Andrographis paniculata.
Jul 05, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicina (Kaunas). 2023 Jul 6 ;59(7). Epub 2023 Jul 6. PMID:
37512069
Article Published Date
: Jul 05, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Glutamine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Astaxanthin mitigates thiacloprid-induced liver injury and immunotoxicity.
Sep 17, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2021 Sep 18 ;19(9). Epub 2021 Sep 18. PMID:
34564187
Article Published Date
: Sep 17, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Astragaloside IV attenuates lipopolysaccharide induced liver injury.
Mar 31, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2023 Apr ;9(4):e15436. Epub 2023 Apr 11. PMID:
37113780
Article Published Date
: Mar 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate.
Jun 13, 2022
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2022 Jun 14:1-9. Epub 2022 Jun 14. PMID:
35698845
Article Published Date
: Jun 13, 2022
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Chemically-Induced Liver Damage
,
Drug Toxicity: Methotrexate
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Methotrexate
[+]
Augmentation of hepatoprotective potential of Aegle marmelos in combination with piperine.
Aug 19, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chem Cent J. 2018 Aug 20 ;12(1):94. Epub 2018 Aug 20. PMID:
30123925
Article Published Date
: Aug 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bael
,
Piperine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Natural Substance Synergy
[+]
Baicalein reduced carbon tetrachloride induced liver damage.
Mar 28, 2021
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2021 Mar 29:9603271211003634. Epub 2021 Mar 29. PMID:
33779329
Article Published Date
: Mar 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Banana peel polyphenols exert a good preventive effect against hepatic injury.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2016 May ;11(5):1947-1954. Epub 2016 Mar 11. PMID:
27168833
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Banana Peel
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Malondialdehyde Down-regulation
[+]
Barley sprouts have a protective effect against alcohol-induced liver injury.
Jul 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID:
27455313
Article Published Date
: Jul 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Bees' honey attenuation of metanil-yellow-induced hepatotoxicity in rats.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2013 ;2013:614580. Epub 2013 Jun 3. PMID:
23818929
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Metanil-Yellow Dye
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Beeswax contains long-chain alcohols which have a preventive effect against chemically-induced liver damage in mice.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2007 Jun;10(2):379-83. PMID:
17651079
Article Published Date
: Jun 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Beeswax
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Beetroot juice prevents adverse changes associated with chemically-induced mammary cancer promotion.
Feb 28, 2013
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2013 Mar 1. Epub 2013 Mar 1. PMID:
23450834
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Chemopreventive
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2012 Jun ;50(6):2027-33. Epub 2012 Mar 24. PMID:
22465004
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
,
DNA damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
N-nitrosodiethylamine
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Beetroot protects the liver against chemical toxicity.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2006 Feb;77(2):91-3. Epub 2005 Dec 20. PMID:
16376022
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Beetroot water extract could be used following silver nano particles as a potential therapeutic intervention to minimize liver toxicity.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2020 ;15:3471-3482. Epub 2020 May 15. PMID:
32547008
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Silver
[+]
Benefits of Chlorella vulgaris against cadmium chloride-induced hepatic and renal toxicities.
Aug 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomedicines. 2023 Aug 29 ;11(9). Epub 2023 Aug 29. PMID:
37760855
Article Published Date
: Aug 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Cadmium
[+]
Berbamine ameliorates ethanol-induced liver injury by inhibition of hepatic inflammation.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2020 Mar ;18(3):186-195. PMID:
32245588
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Berbamine
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Berberine exerts a protective action against carbon tetrachloride induced acute liver injury.
Aug 05, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Aug 6. Epub 2019 Aug 6. PMID:
31432116
Article Published Date
: Aug 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
[+]
Berberine exhibits notable preventive effects on acetaminophen induced hepatotoxicity.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Jul ;103:1319-1326. Epub 2018 May 7. PMID:
29864914
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Berberine hydrochloride attenuates liver injury induced by acute hypoxic exposure.
Dec 31, 2021
Click here to read the entire abstract
Pubmed Data
: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2022 Jan ;38(1):48-53. PMID:
35078575
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine mitigates acetamiprid-induced hepatotoxicity and inflammation.
Jul 31, 2023
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2023 Aug ;30(37):87412-87423. Epub 2023 Jul 8. PMID:
37421530
Article Published Date
: Jul 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Pesticides
[+]
Berberine offered protection against sodium nitrite-induced oxidative injury in liver.
Jan 18, 2023
Click here to read the entire abstract
Pubmed Data
: Curr Drug Saf. 2023 Jan 19. Epub 2023 Jan 19. PMID:
36655525
Article Published Date
: Jan 18, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Berberine protects against the hepatic damage induced by Paracetamol
Feb 01, 2000
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2000 Feb ;71(1):25-33. PMID:
11449466
Article Published Date
: Feb 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Paracetamol
[+]
Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney.
Oct 31, 2021
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2021 Nov ;35(11):e22901. Epub 2021 Sep 2. PMID:
34472159
Article Published Date
: Oct 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Kidney Damage: Chemically-Induced
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
N-nitrosodimethylamine
[+]
Betulinic acid mitigates zearalenone-induced liver injury.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2023 Jul ;177:113811. Epub 2023 May 11. PMID:
37179046
Article Published Date
: Jun 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Nrf2 activation
[+]
Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2014 Oct 1 ;280(1):1-9. Epub 2014 Aug 7. PMID:
25110055
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Sep ;38:324-31. Epub 2016 Jun 23. PMID:
27344638
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bisphenol A causes liver damage and selectively alters the neurochemical coding of intrahepatic parasympathetic nerves in juvenile porcine models.
Dec 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Dec 15 ;18(12). Epub 2017 Dec 15. PMID:
29244763
Article Published Date
: Dec 14, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Prenatal Chemical Exposures
Problem Substances
:
Bisphenol A
[+]
Bisphenol A exposure induces cholesterol synthesis and hepatic steatosis.
Aug 26, 2019
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2019 Aug 27 ;133:110786. Epub 2019 Aug 27. PMID:
31470036
Article Published Date
: Aug 26, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Hepatic Steatosis
,
Prenatal Chemical Exposures
Additional Keywords
:
Increased Risk
Problem Substances
:
Bisphenol A
[+]
Bisphenol A induced oxidative stress, inflammatory response, apoptosis and mitochondrial dysfunction in mouse colons and livers.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Sep ;117:109182. Epub 2019 Jul 1. PMID:
31387175
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Problem Substances
:
Bisphenol A
[+]
Bisphenol A promotes hepatic lipid deposition involving Kupffer cell M1 polarization in male mice.
May 11, 2017
Click here to read the entire abstract
Pubmed Data
: J Endocrinol. 2017 May 12. Epub 2017 May 12. PMID:
28500084
Article Published Date
: May 11, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Bisphenol F induces nonalcoholic fatty liver disease-like changes.
Dec 21, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2020 Dec 22 ;271:116304. Epub 2020 Dec 22. PMID:
33401208
Article Published Date
: Dec 21, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Problem Substances
:
Bisphenol F
[+]
Bisphenol S induced dysregulations in liver; iron regulatory genes and inflammatory mediators.
Jun 29, 2022
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2022 Jun 30. Epub 2022 Jun 30. PMID:
35771333
Article Published Date
: Jun 29, 2022
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol S
[+]
Bitter apple fruit possess significant hepatoprotective and antioxidant activity.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2015 May ;28(3):951-7. PMID:
26004728
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Apple
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Paracetamol
[+]
Black garlic exhibited significant protective effects on carbon tetrachloride-induced acute hepatic injury.
Mar 19, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Mar 20 ;24(6). Epub 2019 Mar 20. PMID:
30897831
Article Published Date
: Mar 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Garlic
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Black tea extract has a protective effect on the levels of lipid peroxidation and antioxidant enzymes in liver of mice with pesticide-induced liver injury.
Jul 01, 2006
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2006 Jul-Aug;24(4):327-32. PMID:
15991261
Article Published Date
: Jul 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Black tea theaflavins could protect against liver and kidney damage.
May 17, 2021
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2021 May 18. Epub 2021 May 18. PMID:
34003645
Article Published Date
: May 17, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Theaflavins
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Renoprotective
[+]
Blueberries have preventive effect on carbon tetrachloride-induced hepatic fibrosis.
Aug 19, 2018
Click here to read the entire abstract
Pubmed Data
: Zhonghua Gan Zang Bing Za Zhi. 2018 Aug 20 ;26(8):590-595. PMID:
30317790
Article Published Date
: Aug 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Blueberry components could regulate histone acetylation and improve liver pathologic changes in rats with carbon tetrachloride-induced disease.
Feb 15, 2017
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2017 Feb 16 ;16(1). Epub 2017 Feb 16. PMID:
28218781
Article Published Date
: Feb 15, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Disease
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Blueberry prevents chemically-induced hepatic fibrosis in rats.
Jun 07, 2010
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2010 Jun 7;16(21):2657-63. PMID:
20518088
Article Published Date
: Jun 07, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
[+]
Boysenberry anthocyanins is a food component available to prevent liver injury.
Dec 31, 2003
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2004 ;21(1-4):259-61. PMID:
15630207
Article Published Date
: Dec 31, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Berries: All
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
BPA and its alternatives BPF and BPAF exaggerate hepatic lipid metabolism disorders in male mice fed a high fat diet.
Jan 08, 2023
Click here to read the entire abstract
Pubmed Data
: Sci Total Environ. 2023 Jan 9:161521. Epub 2023 Jan 9. PMID:
36632902
Article Published Date
: Jan 08, 2023
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
High Fat Diet
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
BPA has a significant impact on the liver miRNome and transcriptome in adult zebrafish.
Oct 12, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Genes (Basel). 2017 Oct 13 ;8(10). Epub 2017 Oct 13. PMID:
29027980
Article Published Date
: Oct 12, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Liver Cancer
Additional Keywords
:
Risk Factors
Problem Substances
:
Bisphenol A
[+]
BPA induced liver fibrosis, which is related to the stimulation of the inflammatory response.
Dec 06, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Exp Pathol. 2016 Dec 7. Epub 2016 Dec 7. PMID:
27925325
Article Published Date
: Dec 06, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
,
Liver Fibrosis
,
Oxidative Stress
Problem Substances
:
Bisphenol A
[+]
Brazilian green propolis suppresses acetaminophen-induced hepatocellular necrosis.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Toxicol Pathol. 2018 Oct ;31(4):275-282. Epub 2018 Jul 1. PMID:
30393431
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Brazillian
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Brewer's yeast (S. cerevisiae) has a protective effect against chemically-induced liver damage in rats.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2009 Jun;28(3):338-45. Epub 2009 Feb 23. PMID:
19233522
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Yeast
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Broccoli sprout extract protected the liver from various types of xenobiotic substances through induction of detoxification enzymes and glutathione synthesis.
Sep 20, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2015 Sep 21 ;21(35):10091-103. PMID:
26401074
Article Published Date
: Sep 20, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli Sprouts
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Phase I Detoxification Enzyme Inducer
,
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
Problem Substances
:
Acetaminophen
[+]
Bromelain modulates liver injury, hematological, molecular, and biochemical perturbations induced by aluminum.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2022 ;2022:5342559. Epub 2022 Nov 21. PMID:
36452063
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bromelain
Diseases
:
Aluminum Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Aluminum
[+]
Butterbur extract improves lipid profiles and antioxidant activities in monosodium L-glutamate-challenged mice.
Sep 30, 2010
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Oct ;13(5):1216-23. PMID:
20828319
Article Published Date
: Sep 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Butterbur
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Monosodium Glutamate (MSG)
[+]
Butylated hydroxytoluene (BHT) exhibits liver toxicity in rats.
Apr 01, 1999
Click here to read the entire abstract
Pubmed Data
: Histol Histopathol. 1999 Apr;14(2):391-406. PMID:
10212800
Article Published Date
: Apr 01, 1999
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Butylated Hydroxytoluene (BHT)
[+]
Butylated hydroxytoluene (BHT) potentiates vitamin A induced liver damage in rats.
Aug 01, 1987
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 1987 Aug;90(1):1-9. PMID:
3629584
Article Published Date
: Aug 01, 1987
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Additional Keywords
:
Drug-Plant-Vitamin Synergies
Problem Substances
:
Butylated Hydroxytoluene (BHT)
[+]
C. longa administration decreased HSC activation and ameliorated hepatotoxic changes caused by cadmium in adult rats.
Jan 20, 2016
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2016 Jan 21:1-12. Epub 2016 Jan 21. PMID:
26796199
Article Published Date
: Jan 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Turmeric
Diseases
:
Cadmium Poisoning
,
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Caffeic acid phenethyl ester mitigates cadmium-induced hepatotoxicity.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ecotoxicol Environ Saf. 2021 Jan 1 ;207:111578. Epub 2020 Nov 3. PMID:
33254423
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
,
MicroRNA modulator
Problem Substances
:
Cadmium
[+]
Camel milk either alone or in combination with bee honey ameliorated the toxic effects of carbon tetrachloride.
May 29, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 May 30:1-10. Epub 2016 May 30. PMID:
27455095
Article Published Date
: May 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
,
Honey
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Carnosic acid attenuates arsenic-induced hepatotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:1421438. Epub 2018 May 2. PMID:
29854073
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Arsenic
[+]
Carob honey has high antioxidant content, antioxidant property, and protective effect against carbon tetrachloride induced kidney and liver toxicity.
Oct 16, 2018
Click here to read the entire abstract
Pubmed Data
: Arch Med Res. 2018 Oct 17. Epub 2018 Oct 17. PMID:
30342848
Article Published Date
: Oct 16, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Renoprotective
[+]
Carrot extract protects the liver from chemical injury.
Jul 07, 1995
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 1995 Jul 7;47(2):69-74. PMID:
7500638
Article Published Date
: Jul 07, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Carrot
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Carthamus red may serve as a candidate with strong a hepatoprotective effect and antioxidant activity in liver damage.
Jul 08, 2013
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2013 Jul 9 ;148(2):570-8. Epub 2013 May 14. PMID:
23684718
Article Published Date
: Jul 08, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Safflower
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Additional Keywords
:
Plant Extracts
[+]
Carvacrol may be a promising protective agent in λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2023 Jul ;38(7):1535-1547. Epub 2023 Mar 22. PMID:
36947485
Article Published Date
: Jun 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Kidney Damage: Chemically-Induced
,
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Renoprotective
Problem Substances
:
Pesticides
[+]
Carvacrol normalizes elevated liver enzymes induced by d-galactosamine-induced hepatotoxicity in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Fundam Clin Pharmacol. 2009 Dec;23(6):757-65. Epub 2009 Jul 24. PMID:
19650854
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
,
Gamma-glutamyl transpeptidase: Elevated
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Carvacrol prevents acrylamide-induced oxidative and inflammatory liver damage and dysfunction.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1161448. Epub 2023 Apr 5. PMID:
37089925
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Acrylamide-induced toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Acrylamide
[+]
Carvacrol protects rat liver exposed to formaldehyde by regulating oxidative stress, and asprosin and subfatin hormones.
Oct 31, 2023
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2023 Nov ;98(5):336-345. Epub 2023 Mar 13. PMID:
36912062
Article Published Date
: Oct 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Chemically-Induced Liver Damage
,
Formaldehyde Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Formaldehyde
[+]
Carvacrol suppresses the progression of liver fibrosis.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2019 Feb ;41(1):163-171. Epub 2019 Feb 1. PMID:
30706740
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Celery extract protects against pesticide-induced toxicity.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2011 Nov 1. Epub 2011 Nov 1. PMID:
22045891
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Celery
,
Flavonoids
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Dichlorvos
,
Organophosphates
,
Pesticides
Adverse Pharmacological Actions
:
Hepatotoxic
,
Oxidant
[+]
Celosia cristata extract prevented oxidative stress-induced liver injury by enhancing hepatocyte antioxidant abilities.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2015 Feb 1 ;168:572-9. Epub 2014 Jul 31. PMID:
25172750
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Celosia cristata (cockscomb)
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Centella asiantica has a protective effect against acute liver injury in mice.
Feb 17, 2010
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2010 Feb 17. Epub 2010 Feb 17. PMID:
20171071
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Centella asiatica
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Centella asiatica may be useful in preventing liver damage.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Nov ;14(5):4521-4528. Epub 2016 Oct 5. PMID:
27748812
Article Published Date
: Oct 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-10 downregulation
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Chemical characteristics, antioxidant capacities and hepatoprotection of polysaccharides from pomegranate peel.
Dec 14, 2018
Click here to read the entire abstract
Pubmed Data
: Carbohydr Polym. 2018 Dec 15 ;202:461-469. Epub 2018 Sep 7. PMID:
30287023
Article Published Date
: Dec 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
Chickpea extract exhibits a significant hepatoprotective effect against carbon tetrachloride induced liver injury in rats.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:344. Epub 2016 Sep 28. PMID:
27733831
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Chickpea
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Chicory ameliorates nitrosamine precusor induced oxidative stress and liver injury.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2163-9. Epub 2010 May 15. PMID:
20478349
Article Published Date
: Aug 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Chicory
Diseases
:
Chemically-Induced Liver Damage
,
Nitrosamnine-induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Chinese tea alleviates carbon tetrachloride-induced liver injury.
Feb 23, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 Feb 24 ;14(5). Epub 2022 Feb 24. PMID:
35267945
Article Published Date
: Feb 23, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Green Tea
,
Oolong tea
,
White Tea
,
Yellow Tea
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Chlorella has hepatoprotective properties against tetrachloride-induced oxidative damage in rats.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: In Vivo. 2009 Sep-Oct;23(5):747-54. PMID:
19779110
Article Published Date
: Sep 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Chlorella vulgaris ameliorates sodium nitrite-induced hepatotoxicity.
Nov 04, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2020 Nov 5. Epub 2020 Nov 5. PMID:
33151487
Article Published Date
: Nov 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice.
Jul 07, 2011
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2011 Jul 7. Epub 2011 Jul 7. PMID:
21741806
Article Published Date
: Jul 07, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage
Pharmacological Actions
:
Glutathione Upregulation
,
Hepatoprotective
[+]
Chlorogenic acid alleviates thioacetamide-induced toxicity and promotes liver development.
Nov 20, 2021
Click here to read the entire abstract
Pubmed Data
: Aquat Toxicol. 2021 Nov 21 ;242:106039. Epub 2021 Nov 21. PMID:
34856462
Article Published Date
: Nov 20, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Chlorogenic acid could be a potential therapeutic to minimize sodium arsenite-induced hepatic injury.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2020 Feb ;47(2):1161-1171. Epub 2019 Dec 9. PMID:
31820315
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
Problem Substances
:
Arsenic
[+]
Chlorogenic acid, quercetin, coenzyme Q10 and silymarin protect against thioacetamide-induced acute liver toxicity.
Mar 30, 2021
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2021 Mar 31 ;277:119460. Epub 2021 Mar 31. PMID:
33811899
Article Published Date
: Mar 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
,
Coenzyme Q10
,
Quercetin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Biol. 2017 Feb 1 ;11:701-707. Epub 2017 Feb 1. PMID:
28187322
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Aspartame
[+]
Chronic inhalation of e-cigarette vapor may lead to increased inflammation, organ damage, and cardiorenal and hepatic disease.
Jan 30, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Regul Integr Comp Physiol. 2018 Jan 31. Epub 2018 Jan 31. PMID:
29384700
Article Published Date
: Jan 30, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
Problem Substances
:
Electronic Cigarettes
[+]
Chrysin has a positive influence on hepatic marker enzymes in chemically-induced liver toxicity in rats.
Mar 31, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Mar 31. Epub 2010 Mar 31. PMID:
20362027
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
,
Gamma-glutamyl transpeptidase: Elevated
,
GGT
,
Results for Liver Enzymes: Elevated AST
Pharmacological Actions
:
Hepatoprotective
[+]
Cissus quadrangularis protects gainst isoniazid-induced liver damage in rats.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Indian J Pharmacol. 2010 Dec;42(6):397-400. PMID:
21189914
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cissus quadrangularis
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Citrus maxima peel powder produced significant hepatoprotective action in carbon tetrachloride administered rats.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:598179. Epub 2015 May 28. PMID:
26106435
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Citrus Peel
Diseases
:
Chemically-Induced Liver Damage
,
Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Cloudy apple juice potentiates hepatoprotection during experimental liver injury.
Aug 20, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Aug 21 ;140:1006-1017. Epub 2019 Aug 21. PMID:
31445146
Article Published Date
: Aug 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apple
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
[+]
Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice.
Jun 24, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2018 Jun 25 ;18(1):195. Epub 2018 Jun 25. PMID:
29940935
Article Published Date
: Jun 24, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Coconut Water
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Coenzyme-Q10 exerts hepatoprotective effect in fructose-induced fatty liver model.
Mar 09, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2020 Mar 10. Epub 2020 Mar 10. PMID:
32157594
Article Published Date
: Mar 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
,
High Fructose Diet
Pharmacological Actions
:
Hepatoprotective
[+]
Colocasia esculenta possesses hepatoprotective activity against thioacetamide in rats.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2015 Nov ;28(6 Suppl):2237-41. PMID:
26687753
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Taro
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Combination of pomegranate extract and curcumin ameliorates thioacetamide-induced liver fibrosis.
Jul 26, 2020
Click here to read the entire abstract
Pubmed Data
: Toxicol Mech Methods. 2020 Jul 27:1-23. Epub 2020 Jul 27. PMID:
32718261
Article Published Date
: Jul 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Combined effects of fluoride and arsenic on mitochondrial function in the liver.
Mar 21, 2023
Click here to read the entire abstract
Pubmed Data
: Appl Biochem Biotechnol. 2023 Mar 22. Epub 2023 Mar 22. PMID:
36947368
Article Published Date
: Mar 21, 2023
Study Type
: Animal Study
Additional Links
Diseases
:
Arsenic Poisoning
,
Chemically-Induced Liver Damage
,
Fluoride Toxicity
Additional Keywords
:
Synergistic Toxicity
Problem Substances
:
Arsenic
,
Sodium Fluoride
[+]
Comparative hepatoprotective effect of Nigella sativa pre- and post-treatment.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2019 Jan ;32(1):205-212. PMID:
30772810
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Prophylactic Agents
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Constituents of L. fulvotomentosa and L. macranthoide are effective in decreasing carbon tetrachloride and D-Galactosamine-induced liver injuries.
May 31, 1999
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 1999 Jun ;24(6):363-4, 384. PMID:
12212032
Article Published Date
: May 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Cordyceps exhibits potent hepatoprotective properties in an animal model.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2010 Jan;81(1):1-7. Epub 2009 Jul 8. PMID:
19596425
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps sinensis
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Cow urine distillate attenuates chemically-induced liver damage in rats.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Biomed Environ Sci. 2009 Aug;22(4):345-7. PMID:
19950531
Article Published Date
: Aug 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Urine
,
Urine: Cow
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
[+]
Cranberry extract exhibits promising hepatoprotective potential against the chemical induced hepatotoxicity.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2017 Nov ;10(11):1054-1058. Epub 2017 Oct 27. PMID:
29203101
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cranberry
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Crocin attenuates CCl 4-induced liver fibrosis via PPAR-γ mediated modulation of inflammation and fibrogenesis in rats.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2020 Dec ;39(12):1639-1649. Epub 2020 Jul 7. PMID:
32633567
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Crocin has protective activities against ethanol toxic effects in the liver and kidney.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2020 Jan ;23(1):51-62. PMID:
32405348
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
,
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Crocus sativus hydroalcoholic extract has beneficial effects on inflammatory and enzymatic indices resulting from alcohol use in kidney and liver.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inflamm Res. 2019 ;12:269-283. Epub 2019 Oct 8. PMID:
31632125
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Cucurbitacin-B attenuates carbon tetrachloride induced hepatic fibrosis in mice through inhibition of STAT-3.
Dec 16, 2017
Click here to read the entire abstract
Pubmed Data
: Chem Biol Drug Des. 2017 Dec 17. Epub 2017 Dec 17. PMID:
29250925
Article Published Date
: Dec 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
,
STAT3 Inhibitor
[+]
Curcuma longa extract or curcumin has the ability to alleviate the hepatotoxic effects caused by mercuric chloride in rats.
Mar 19, 2017
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2017 Mar 20. Epub 2017 Mar 20. PMID:
28336172
Article Published Date
: Mar 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Turmeric
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Mercury
[+]
Curcumin ameliorates acute thioacetamide-induced hepatotoxicity.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Gastroenterol Hepatol. 2006 Feb;21(2):358-66. PMID:
16509859
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Enzyme Inhibitors
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Curcumin ameliorates chemically-induced liver damage and fibrosis in rats.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Ann Hepatol. 2011 Oct 1 ;10(4):516-30. PMID:
21911894
Article Published Date
: Oct 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin ameliorates lead-induced hepatotoxicity.
Nov 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomolecules. 2019 Nov 5 ;9(11). Epub 2019 Nov 5. PMID:
31694300
Article Published Date
: Nov 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Lead
[+]
Curcumin and capsaicin individually are protective to LDL oxidation both in vivo and in vitro, to iron-induced hepatotoxicity and to carrageenan-induced inflammation.
Aug 26, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Aug 26;57(16):7401-8. PMID:
16956363
Article Published Date
: Aug 26, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Capsaicin
,
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Cholesterol: Oxidation
,
Inflammation
,
Iron Poisoning
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Natural Substance Synergy
[+]
Curcumin and NAC protect against valproate-induced liver toxicity.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Arzneimittelforschung. 2010;60(11):647-53. PMID:
21175036
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
NAC (N-acetyl-L-cysteine)
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity: Valproic Acid (Depakote)
Pharmacological Actions
:
Anticonvulsants
,
Antioxidants
,
Hepatoprotective
[+]
Curcumin and saikosaponin A inhibit chemical-induced liver inflammation and fibrosis in rats.
Jul 24, 2007
Click here to read the entire abstract
Pubmed Data
: Mol Vis. 2007 Jul 24;13:1291-7. PMID:
20128048
Article Published Date
: Jul 24, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Saikosaponin
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Inflammation
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Curcumin and selenium can hinder the progression and severity of liver injury during acute inflammatory episodes.
Oct 24, 2019
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2019 Oct 25. Epub 2019 Oct 25. PMID:
31654258
Article Published Date
: Oct 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Selenium
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Diclofenac
[+]
Curcumin and turmeric extract might be recommendable to recover liver activity.
Jul 25, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Jul 26 ;7(1):6513. Epub 2017 Jul 26. PMID:
28747775
Article Published Date
: Jul 25, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Turmeric
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Curcumin attenuated the lipid peroxidation and apoptotic liver injury in copper-overloaded rats
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: Zhonghua Er Ke Za Zhi. 2007 Aug;45(8):604-8. PMID:
18021535
Article Published Date
: Aug 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Copper Toxicity
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin attenuates alcohol toxicity.
Aug 20, 2004
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharm Sci. 2004 Aug 20;7(2):274-83. Epub 2004 Aug 20. PMID:
15367386
Article Published Date
: Aug 20, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Curcumin attenuates Concanavalin A-induced liver injury in mice.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2012 Jan ;12(1):151-7. Epub 2011 Dec 2. PMID:
22138522
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Curcumin attenuates dimethylnitrosamine-induced liver injury in rats.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2008 Apr;46(4):1279-87. Epub 2007 Sep 26. PMID:
18006204
Article Published Date
: Apr 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Hepatoprotective
[+]
Curcumin effectively protects against zinc oxide nanoparticle induced hepatotoxicity in rats.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Balkan Med J. 2016 May ;33(3):252-7. Epub 2016 May 1. PMID:
27308068
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Nanoparticles
[+]
Curcumin functions as an anti-inflammatory and antioxidant agent on arsenic-induced hepatic and kidney injury.
Jul 16, 2021
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2021 Jul 17. Epub 2021 Jul 17. PMID:
34272803
Article Published Date
: Jul 16, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
,
Renoprotective
Problem Substances
:
Arsenic
[+]
Curcumin has a protective effect against nicotine-induced genotoxicity on rat liver.
Jul 07, 2008
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2008 Jul 7;588(2-3):151-7. Epub 2008 Apr 15. PMID:
18508046
Article Published Date
: Jul 07, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
DNA damage
,
Nicotine/Tobacco Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin induces recovery from hepatic injury.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Indian J Biochem Biophys. 2008 Oct;45(5):317-25. PMID:
19069843
Article Published Date
: Oct 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Apoptotic
,
Hepatoprotective
[+]
Curcumin inhibits chemically-induced liver cancer.
Nov 01, 2000
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2000 Nov;38(11):991-5. PMID:
11038236
Article Published Date
: Nov 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Chemopreventive
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
[+]
Curcumin intervention ameliorates the AFB(1) induced toxicity.
Feb 17, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Feb 17;127(3):641-4. Epub 2009 Dec 14. PMID:
20015472
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Aflatoxicosis
,
Chemically-Induced Liver Damage
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Curcumin prevents chemically-induced liver cancer.
Mar 30, 2007
Click here to read the entire abstract
Pubmed Data
: Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):439-42. Epub 2006 Dec 15. PMID:
10657978
Article Published Date
: Mar 30, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Curcumin prevents liver fibrosis.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2009 Oct;63(4):415-20. Epub 2009 Jun 25. PMID:
19554395
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Fibrotic
,
Apoptotic
[+]
Curcumin protects against acetaminophen-induced toxicity.
Jan 16, 2012
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2012 Jan 16. Epub 2012 Jan 16. PMID:
22272768
Article Published Date
: Jan 16, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Apoptotic
,
Hepatoprotective
[+]
Curcumin protects against acute liver damage in the rat.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta. 2007 Jun;1770(6):989-96. Epub 2007 Feb 22. PMID:
17383825
Article Published Date
: Jun 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Curcumin protects against alcohol and oxidized fat-induced liver toxicity.
Jul 01, 2004
Click here to read the entire abstract
Pubmed Data
: Ital J Biochem. 2004 Jul;53(2):61-6. PMID:
15646009
Article Published Date
: Jul 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor