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Chemotherapy-Induced Toxicity
Views 11116
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353 Substances Researched for Chemotherapy-Induced Toxicity
Name
AC
CK
Focus
Curcumin
60
103
Magnesium
10
94
Ginsenosides
29
67
Vitamin E
11
47
Thymoquinone
19
37
Chokeberry
4
32
Ginger
12
31
Resveratrol
17
31
Homeopathic Medicine: Traumeel
2
30
Bee Propolis
3
28
Melatonin
12
28
Alpha-Lipoic Acid
10
27
NAC (N-acetyl-L-cysteine)
10
26
Nigella sativa (aka Black Seed)
14
26
Reishi Mushroom
9
26
Vitamin C
15
25
Probiotics
8
24
Coenzyme Q10
7
23
Folic Acid
2
22
Grape Seed Extract
10
22
Silibinin
2
22
Sulforaphane
12
22
Oleuropein
7
21
Acetyl-l-carnitine
2
20
Calendula
1
20
Ellagic Acid
10
20
Flavonoids
12
20
Garlic
11
20
Homeopathic Medicine: All
1
20
Royal Jelly
6
20
Sodium Bicarbonate
1
20
Vitamin B-12
1
20
Wheat Grass
1
20
Astaxanthin
10
19
Caffeic acid phenethyl ester
9
19
Onion
4
19
Rutin
11
19
Astragaloside
8
18
Carnitine
4
18
L-Carnitine
4
16
Chrysin
9
15
Citrus naringin
8
15
Genistein
5
15
Zataria multiflora
8
15
Astragalus
4
14
Ginkgo biloba
7
14
Isoflavones
4
14
Quercetin
11
14
EGCG (Epigallocatechin gallate)
8
13
Naringenin
6
13
Neem
3
13
Anthocyanins
7
12
Cannabidiol
6
12
Codonopsis pilosula
2
12
Echinacea
2
12
Ginseng
7
12
Green Tea
5
12
Palmitoylethanolamide
2
12
Panax Notoginseng
5
12
Pomegranate
8
12
St. Johns Wort
2
12
Vitamin D
2
12
Wheat Germ
2
12
Angelica
2
11
Cannabis
2
11
Glutamine
2
11
Paeonol
6
11
Tanshinone IIA
7
11
AHCC
3
10
Allicin
5
10
Bifidobacterium
1
10
Bifidobacterium Breve
1
10
Caffeine
1
10
Carvacrol
5
10
Cordyceps sinensis
5
10
Geranium
1
10
Ginseng (Korean)
5
10
Honey: Life Mel Proprietary Formula
1
10
Honokiol
6
10
Lactobacillus plantarum
5
10
Medicinal Mushrooms
5
10
Multivitamin
1
10
Saccharomyces Boulardii
1
10
Saffron
4
10
Apigenin
6
9
Asiatic Acid
5
9
Chrysanthemum Indicum
3
9
Crocin
5
9
Hesperidin
5
9
Maitake Mushroom
4
9
Spirulina
4
9
Berberine
5
8
Beta-glucan
3
8
Betulinic acid
3
8
Camel Milk
4
8
Flaxseed
4
8
Lycopene
4
8
Mangosteen
2
8
P-Coumaric Acid
5
8
Panax Ginseng
4
8
Fermented Foods and Beverages
4
7
Fucoidan
5
7
Honey
4
7
Indole-3-Carbinol
4
7
Licorice
5
7
Mangiferin
4
7
Myricetin
4
7
Paeoniflorin
5
7
Rosmarinic acid
4
7
Schisandra
3
7
Selenium
4
7
Arginine
3
6
Bael
3
6
Ferulic acid
5
6
Fig
3
6
Gingerol
3
6
Grape
4
6
Huaier (Trametes robiniophila murr)
3
6
Olive leaf extract
3
6
Pomegranate Seed
2
6
Puerarin
3
6
Pycnogenol (Pine Bark)
3
6
Red Sage
3
6
Safflower
3
6
Taurine
3
6
Urolithin A
3
6
White Tea
3
6
Blueberry
3
5
Cordyceps Militaris
3
5
Dates
3
5
Gold (nanoparticles)
3
5
Ligustrazine
3
5
Lotus
5
5
Sesamol
4
5
Soy
1
5
Amla Fruit
2
4
Bacopa
2
4
Bai Zhu
2
4
Beta-Caryophyllene
2
4
Bile salts
1
4
Bitter Apple
2
4
Blackberry
2
4
Cannabinoids
3
4
Clove
2
4
Delta-tetrahydrocannabinol (THC)
2
4
Diallyl sulfide
2
4
Eugenol
2
4
Fenugreek
2
4
Fisetin
2
4
Gallic Acid
2
4
Garlic: Aged
2
4
Geraniol
2
4
Gotu Kola
2
4
Hawthorn
2
4
Hydrogen Water
2
4
Lactobacillus Acidophilus
2
4
Lactobacillus paracasei
2
4
Lactobacillus rhamnosus
2
4
Lemon Peel
1
4
Luteolin
3
4
Milk Thistle
2
4
Moringa oleifera
2
4
Nordihydroguaiaretic acid (NDGA)
2
4
Oleanolic acid
2
4
Oligosaccharides
2
4
Omega-3 Fatty Acids
2
4
Parsley
2
4
Patchouli
2
4
Phloretin
3
4
Piperidines
1
4
Piperine
2
4
Plantago
2
4
Polyphenols
3
4
Pomegranate Peel
2
4
Pumpkin Seeds
2
4
Punicalagin
3
4
Red Wine Extract
1
4
Rhubarb
2
4
Rosemaric Acid
3
4
Rubia Cordifolia
1
4
Seaweed: Brown
2
4
Spikenard
2
4
Tangeretin
3
4
Tannic Acid
2
4
Testosterone
1
4
Vanillin
2
4
Walnut
2
4
Achiote
2
3
Aloe Vera
2
3
Bee Venom
2
3
Emodin
3
3
Formononetin
2
3
Peony
2
3
Poria cocos
2
3
Riboflavin (Vitamin B-2)
2
3
Sea buckthorn
2
3
Vitamin E: alpha tocopherol
2
3
Watercress
2
3
White Mulberry
2
3
Wogonin
2
3
Apricot Kernel
1
2
Artemisinin
1
2
Ashwagandha
1
2
Barberry
1
2
Basil
1
2
Bee Pollen
1
2
Bergamot
1
2
Betaine
1
2
Betanin
1
2
Bifidobacterium Bifidum
1
2
Bifidobacterium Lactis
1
2
Bilberry
1
2
Biochanin A
1
2
Bitter Orange
1
2
Bixin
2
2
Boerhaavia diffusa
1
2
Buckwheat
1
2
Carrot
1
2
Catechols
1
2
Celery
1
2
Chickpea
1
2
Chlorella (Algae)
1
2
Cinnamaldehyde
1
2
Cinnamic acid
1
2
Citrus Peel
1
2
Coconut Husk/Fiber
1
2
Coconut Oil
1
2
Coriandrum sativum
1
2
Corn Silk
1
2
Corn: Purple
1
2
Crocetin
1
2
Curry Leaves
1
2
Cyanidin 3-glucoside
1
2
D-Limonene
1
2
Diosgenin
1
2
Dogwood
1
2
Eriodictyol
1
2
Eucalyptus
1
2
Evening Primrose Oil
1
2
Fucoxanthin
1
2
Ginseng (American)
1
2
Glycyrrhizin
1
2
Goji
1
2
Grapes
1
2
Guava
1
2
Guduchi
1
2
Hazelnut
1
2
Hemp Seed
1
2
Hibiscus sabdariffa
1
2
Homeopathic Arsenicum album
1
2
Honeysuckle
1
2
Horehound
1
2
Horsetail
1
2
Hu Zhang (Polygonum cuspidatum)
1
2
Hydrangea
1
2
Indian Mulberry
1
2
Kaempferol
1
2
Kefir
1
2
Kimchi
1
2
Kombucha Tea
1
2
Lactobacillus casei
1
2
Lecithin
1
2
Liquiritigenin
1
2
Loquat Seeds
1
2
Lutein
1
2
Lychee
1
2
Magnolol
1
2
Mango
1
2
Manuka Honey
1
2
Marjoram
1
2
Meadowsweet
1
2
Methionine
1
2
Modified Citrus Pectin
1
2
Mustard Greens
1
2
Nettle
1
2
Nobiletin
1
2
Noni
1
2
Okra
1
2
Olive Oil
1
2
Orange
1
2
Orange: Mandarin
1
2
Organosulfur Compounds
1
2
Orthosiphon
1
2
Passion fruit
1
2
Pine Bark Extract
1
2
Plantago major
1
2
Prickly Pear Cactus
1
2
Pterostilbene
1
2
Purslane
1
2
Quince
1
2
Raspberry
1
2
Raspberry ketone
1
2
Rehmannia
2
2
Rooibos
2
2
Salvia miltiorrhiza
1
2
Sandalwood
1
2
Seaweed
1
2
Sesamin
1
2
Silver (nanoparticles)
1
2
Silymarin
1
2
Soup
1
2
Stilbenes
1
2
Strawberry
1
2
Sumac
1
2
Superoxide dismutase
1
2
Tetrahydrocurcumin
1
2
Theanine
1
2
Thyme
1
2
Thymol
1
2
Tocotrienol: Delta
2
2
Trichosanthes Kirilowii
1
2
Turmeric
1
2
Turmeric: Fermented
1
2
Ursolic Acid
1
2
Vitamin E: Gamma-Tocopherol
1
2
Vitexins
1
2
Water: Deep Sea
2
2
Water: Deuterium Depleted
1
2
Woodfordia fruticosa
1
2
Xanthohumol
1
2
Yarrow
1
2
Zinc
1
2
18β-Glycyrrhetinic Acid
1
1
Alpha Linolenic Acid
1
1
Antrodia cinnamomea
1
1
Benzyl isothiocyanate
1
1
Bisdemethoxycurcumin
1
1
Black Tea
1
1
Caffeic Acid
1
1
Camu Camu
1
1
Capparis spinosa (caper)
1
1
Capsaicin
1
1
Catechin
1
1
Celastrol
1
1
Curcuminoids
1
1
Cysteine (see N-Acetylcysteine)
1
1
Daidzein
1
1
Eggplant
1
1
Genipin
1
1
Gold
1
1
Hyperforin
1
1
Isoliquiritigenin
1
1
Jujube
1
1
Lettuce
1
1
Marijuana
1
1
Persimmon
1
1
Phyllanthus urinaria
1
1
Piceatannol
1
1
Pumpkin
1
1
Rice Bran
1
1
Rosemary
1
1
Sweet Orange
1
1
Tocotrienols
1
1
23 Problem Substances Researched for Chemotherapy-Induced Toxicity
Name
AC
CK
Focus
Cisplatin
14
42
Cyclophosphamide
14
30
Chemotherapy
2
22
Doxorubicin
7
13
Paclitaxel
5
12
Atorvastatin
1
10
Dl-alpha-tocopherol acetate
1
10
Tamoxifen
1
10
Bleomycin
3
9
Arsenic Trioxide
4
6
Fluorouracil (5-FU or f5U)
3
5
Nicotine
3
3
Acetaminophen
1
2
Monosodium Glutamate (MSG)
1
2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
1
2
Paracetamol
1
2
Benzo(a)pyrene
1
1
Bisphenol A
1
1
Cadmium
1
1
Cyclosporins
1
1
Isoproterenol
1
1
Methotrexate
1
1
Streptozotocin
1
1
14 Therapeutic Actions Researched for Chemotherapy-Induced Toxicity
Name
AC
CK
Focus
Cryotherapy
3
31
Exercise
3
24
Dietary Modification: Mediterranean Diet
1
10
Fasting/Caloric Restriction
1
10
Homeopathic Treatment
1
10
Hyperbaric Treatment
2
5
Laser Treatment: Low-Level
2
3
Dietary Modification: Low Calorie Diet
1
2
Exercise: Aerobic
1
2
Light-Emitting Diodes (LEDs) Therapy
1
2
Microbiota Transfer Therapy
1
2
Traditional Chinese Medicine
1
2
Guided Imagery
1
1
Ozone Therapy
1
1
4 Problematic Actions Researched for Chemotherapy-Induced Toxicity
Name
AC
CK
Focus
Chemotherapy
11
71
Radiotherapy
2
12
Electromagnetic Field Harms
1
1
Electromagnetic Radiation
1
1
Research Articles
936
Cumulative Knowledge Score
1514
Overall Research Rating
EXCELLENT
Related Topics
The Following are Sub-Topics of Chemotherapy-Induced Toxicity
Cardiotoxicity: Chemotherapy-Induced
Chemotherapy Induced Myelotoxicity
Chemotherapy-Induced Liver Toxicity
Chemotherapy-Induced Toxicity: Cyclophosphamide
Chemotherapy-Induced Toxicity: 5-fluorouracil
Chemotherapy-Induced Toxicity: Adriamycin
Chemotherapy-Induced Toxicity: Arsenic Trioxide
Chemotherapy-Induced Toxicity: Bleomycin
Chemotherapy-Induced Toxicity: Cisplatin
Chemotherapy-Induced Toxicity: Doxorubicin
Chemotherapy-Induced Toxicity: Epirubicin
Chemotherapy-Induced Toxicity: FOLFOX
Chemotherapy-Induced Toxicity is a Sub of the following Topic
Chemotherapy and Radiation Toxicity
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View the Evidence:
1240 Abstracts with Chemotherapy-Induced Toxicity Research
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[+]
Ginsenoside Rg3 for chemotherapy-induced myelosuppression.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:649. Epub 2020 May 12. PMID:
32477128
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy Induced Myelotoxicity
Pharmacological Actions
:
Chemoprotective Agents
,
Immunomodulatory
[+]
There are high rates of behavioral symptoms in breast cancer survivors, particularly those treated with chemotherapy
Aug 08, 2011
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2011 Aug 8. Epub 2011 Aug 8. PMID:
21825266
Article Published Date
: Aug 08, 2011
Study Type
: Meta Analysis
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity
,
Depression
,
Fatigue
,
Inflammation
,
Insomnia
Anti Therapeutic Actions
:
Chemotherapy
Problem Substances
:
Chemotherapy
Adverse Pharmacological Actions
:
Inflammatory
,
Tumor necrosis factorα (TNFα) up-regulation
[+]
There is evidence to support the use of topical calendula for prophylaxis of acute dermatitis during radiotherapy and Traumeel S mouthwash in the treatment of chemotherapy-induced stomatitis.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cochrane Database Syst Rev. 2009(2):CD004845. Epub 2009 Apr 15. PMID:
19370613
Article Published Date
: Jan 01, 2009
Study Type
: Meta Analysis
Additional Links
Substances
:
Calendula
,
Homeopathic Medicine: All
,
Homeopathic Medicine: Traumeel
Diseases
:
Breast Cancer
,
Cancers: All
,
Chemotherapy-Induced Toxicity
,
Dermatitis
,
Radiation Induced Illness
,
Radiation Induced Illness: Dermatitis
,
Stomatitis: Aphthous
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Plant Extracts
[+]
These results highlight the potential protective effect of magnesium supplementation on cisplatin-induced acute nephrotoxicity.
Aug 18, 2019
Click here to read the entire abstract
Pubmed Data
: Drugs. 2019 Aug 19. Epub 2019 Aug 19. PMID:
31429065
Article Published Date
: Aug 18, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
A combination of geranium extract, Ganoderma lucidum, Codonopsis pilosula and Angelicae sinensis, improve the condition of cancer patients receiving chemotherapy/radiotherapy.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Jun;23(6):785-90. PMID:
19145638
Article Published Date
: Jun 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Angelica
,
Codonopsis pilosula
,
Geranium
,
Reishi Mushroom
Diseases
:
Cancers: All
,
Chemotherapy-Induced Toxicity
,
Radiation Induced Illness
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
A proprietary honey-based herbal formula reduces chemotherapy-induced neutropenia and the need for colony-stimulating factors.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Med Oncol. 2006;23(4):549-52. PMID:
17303914
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Honey: Life Mel Proprietary Formula
Diseases
:
Cancers: All
,
Chemotherapy-Induced Toxicity
,
Neutropenia
,
Neutropenia: Chemotherapy Induced
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Colony-Stimulating Factors (CSFs)
[+]
A short hydration regimen with 20 mEq of magnesium supplementation is safe and feasible for patients with lung cancer receiving cisplatin-based chemotherapy.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Clin Oncol. 2020 Aug 1. Epub 2020 Aug 1. PMID:
32740717
Article Published Date
: Jul 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Lung Cancer
Pharmacological Actions
:
Chemoprotective Agents
[+]
A short hydration regimen with magnesium supplementation prevents cisplatin-induced nephrotoxicity
Dec 12, 2016
Click here to read the entire abstract
Pubmed Data
: Support Care Cancer. 2016 Dec 13. Epub 2016 Dec 13. PMID:
27966021
Article Published Date
: Dec 12, 2016
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
Additional Keywords
:
Chemoprotective Agents
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Magnesium
[+]
A. melanocarpa may be regarded as a promising new source of bioactive antioxidant natural compounds for breast cancer patients.
Feb 28, 2013
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2013 Mar ;53:126-32. Epub 2012 Dec 5. PMID:
23220617
Article Published Date
: Feb 28, 2013
Study Type
: Human Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Breast Cancer
,
Chemotherapy-Induced Toxicity
,
Nitrite Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Chemotherapeutic
Additional Keywords
:
Drug: Doxorubicin
,
Plant Extracts
[+]
Acetyl L-carnitine treatment improves symptoms of chemotherapy induced neuropathy.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: Eur J Cancer. 2005 Aug;41(12):1746-50. PMID:
16039110
Article Published Date
: Aug 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Acetyl-l-carnitine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Neuropathic Pain
[+]
Acetyl-L-carnitine appears to be an effective and well-tolerated agent for the treatment of chemotherapy-induced peripheral neuropathy.
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Tumori. 2005 Mar-Apr;91(2):135-8. PMID:
15948540
Article Published Date
: Mar 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Acetyl-l-carnitine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Neuropathic Pain
Additional Keywords
:
Drug: Cisplatin
[+]
Acute exercise protects against doxorubicin cardiotoxicity.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Integr Cancer Ther. 2008 Sep;7(3):147-54. PMID:
18815146
Article Published Date
: Sep 01, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Doxorubicin
,
Hypertension
,
Oxidative Stress
Therapeutic Actions
:
Exercise
Additional Keywords
:
Drug: Doxorubicin
[+]
Adjunctive oral cryotherapy is effective for the prophylaxis and relief of oral mucositis and anorexia caused by chemotherapy.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Esophagus. 2019 04 ;16(2):207-213. Epub 2019 Jan 1. PMID:
30600487
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Anorexia: Cancer-Associated
,
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Esophageal Cancer
,
Oral Mucositis
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Anti-Cachexic Agents
,
Chemoprotective Agents
[+]
Administration of Bifidobacterium breve on patients undergoing chemotherapy for pediatric malignancies improves their intestinal environments.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Support Care Cancer. 2010 Jun;18(6):751-9. Epub 2009 Aug 14. PMID:
19685085
Article Published Date
: Jun 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bifidobacterium
,
Bifidobacterium Breve
,
Probiotics
Diseases
:
Chemotherapy-Induced Toxicity
[+]
Alpha lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Exp Neurol. 2008 Dec;214(2):276-84. Epub 2008 Sep 9. PMID:
18809400
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Chemotherapy-Induced Toxicity: Paclitaxel
,
Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions
:
Neuroprotective Agents
[+]
An intravenous hydration regimen supplemented with magnesium prevented cisplatin-induced nephrotoxicity in patients with head and neck cancer.
Feb 01, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Otolaryngol Head Neck Surg. 2018 Feb 2 ;47(1):10. Epub 2018 Feb 2. PMID:
29394952
Article Published Date
: Feb 01, 2018
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Astragalus may provide an ideal complementary treatment to chemotherapy.
Mar 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2008 Mar;46(3):1089-96. Epub 2007 Nov 17. PMID:
12592686
Article Published Date
: Mar 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Astragalus
Diseases
:
Chemotherapy
,
Chemotherapy-Induced Toxicity
[+]
Atorvastatin causes cardiomyopathy when administered in combination with chemotherapy.
Jul 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2007 Jul-Aug;25(4):463-72. PMID:
16906597
Article Published Date
: Jul 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Cardiomyopathy
,
Chemotherapy-Induced Toxicity
Additional Keywords
:
Drug Interaction
Problem Substances
:
Atorvastatin
[+]
Bee honey and royal jelly are effective in reducing cisplatin nephrotoxicity.
May 25, 2017
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2017 May 26:1-5. Epub 2017 May 26. PMID:
28548561
Article Published Date
: May 25, 2017
Study Type
: Human Study
Additional Links
Substances
:
Royal Jelly
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Bi-weekly administration of paclitaxel and cisplatin in patients with advanced esophageal cancer results in amedian survival for all patients of 9 months.
Mar 04, 2002
Click here to read the entire abstract
Pubmed Data
: Br J Cancer. 2002 Mar 4;86(5):669-73. PMID:
11875723
Article Published Date
: Mar 04, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Esophageal Cancer
Additional Keywords
:
Drug: Cisplatin
,
Drug: Paclitaxel
Anti Therapeutic Actions
:
Chemotherapy
[+]
Caffeine potentiates chemotherapy for metastatic osteosarcoma.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Orthop Sci. 2009 Sep;14(5):556-65. Epub 2009 Oct 3. PMID:
19802667
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Caffeine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Lung Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Chemosensitizer
Additional Keywords
:
Drug: Doxorubicin
,
Drug Synergy
[+]
Cannabis extract is safe and efficacious in reducing chemotherapy-induced nauseau and vomiting.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Clin Pharmacol. 2010 Nov;70(5):656-63. PMID:
21039759
Article Published Date
: Nov 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Cannabis
Diseases
:
Chemotherapy
,
Chemotherapy-Induced Toxicity
,
Nausea: Chemotherapy-Induced
Pharmacological Actions
:
Antiemetics
[+]
Carnitine improves fatigue, quality of life, lean body mass and appetite in advanced cancer patients undergoing anticancer therapy.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2006 Feb;22(2):136-45. PMID:
16459226
Article Published Date
: Feb 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Carnitine
Diseases
:
Cancers: All
,
Chemotherapy
,
Chemotherapy-Induced Toxicity
,
Fatigue
,
Quality of Life: Poor
Additional Keywords
:
Antineoplastic Agents
,
Drug Side Effect Attenuation
[+]
Chemotherapy used in advanced gastric or gastroesophageal adenocarcinoma results in an overall median survival time of between 7-9 months.
Mar 20, 2010
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2010 Mar 20;28(9):1547-53. Epub 2010 Feb 16. PMID:
20159816
Article Published Date
: Mar 20, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Esophageal Cancer
,
Gastric Cancer
Additional Keywords
:
Chemotherapy
,
Drug: 5-flourouracil
Anti Therapeutic Actions
:
Chemotherapy
[+]
Children treated for solid tumors or lymphoma with chemotherapy have increased caries of the primary teeth.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Paediatr Dent. 2010 Jan;20(1):15-23. PMID:
20059589
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity
,
Dental Caries
,
Neuroblastoma
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Drug Side Effect Attenuation
[+]
Cisplatin-associated severe acute kidney injury occurs in 20% of the patients and has a negative impact on long-term renal function and patient survival.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015;10(11):e0142225. Epub 2015 Nov 10. PMID:
26556481
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Kidney Damage: Drug-Induced
Additional Keywords
:
Increased Risk
Problem Substances
:
Cisplatin
[+]
Dl-alpha-tocopherol acetate does not protect against chemotherapy-induced chromosome damage and reduces the level of plasma gamma tocopherol.
Feb 01, 2002
Click here to read the entire abstract
Pubmed Data
: Melanoma Res. 2002 Feb;12(1):83-90. PMID:
11828262
Article Published Date
: Feb 01, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Melanoma
Problem Substances
:
Dl-alpha-tocopherol acetate
[+]
Effects of photobiomodulation (660 nm laser) on anthracycline extravasation.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Rev Lat Am Enfermagem. 2022 ;30:e3693. Epub 2022 Oct 17. PMID:
36287401
Article Published Date
: Dec 31, 2021
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Therapeutic Actions
:
Laser Treatment: Low-Level
Pharmacological Actions
:
Chemoprotective Agents
[+]
Exercise preconditioning protects against doxorubicin-induced cardiac dysfunction.
Oct 05, 2006
Click here to read the entire abstract
Pubmed Data
: Vet Microbiol. 2006 Oct 5;117(1):59-65. PMID:
18408619
Article Published Date
: Oct 05, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Doxorubicin
Additional Keywords
:
Drug: Doxorubicin
[+]
Fermented wheat germ extract reduces chemotherapy-induced febrile neutropenia in pediatric patients.
Oct 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Pediatr Hematol Oncol. 2004 Oct;26(10):631-5. PMID:
15454833
Article Published Date
: Oct 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Wheat Germ
Diseases
:
Chemotherapy-Induced Toxicity
,
Neutropenia: Chemotherapy Induced
[+]
Ginger root powder is effective in reducing severity of acute and delayed chemotherapy-induced nausea and vomiting as additional therapy to ondensetron and dexamethasone in patients receiving chemotherapy.
Sep 14, 2010
Click here to read the entire abstract
Pubmed Data
: Pediatr Blood Cancer. 2010 Sep 14. Epub 2010 Sep 14. PMID:
20842754
Article Published Date
: Sep 14, 2010
Study Type
: Human Study
Additional Links
Substances
:
Ginger
Diseases
:
Chemotherapy-Induced Toxicity
,
Nausea: Chemotherapy-Induced
Pharmacological Actions
:
Antiemetics
[+]
High-volume hydration and magnesium supplementation can reduce the renal toxicity induced by cisplatin.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Pharmacol Toxicol. 2014 ;15:70. Epub 2014 Dec 4. PMID:
25472655
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Lung Cancer
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Significant Treatment Outcome
,
Supplementation
[+]
Intravenous magnesium supplementation conferred protective effects against cisplatin-induced nephrotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Jan ;15(1):658-664. Epub 2017 Nov 3. PMID:
29391892
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Esophageal Cancer
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
L-carnitine could enhance the spermatogenesis process after exposure to cisplatin during the prepubertal phase.
Aug 08, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Aug 9:118242. Epub 2020 Aug 9. PMID:
32784056
Article Published Date
: Aug 08, 2020
Study Type
: Human Study
Additional Links
Substances
:
L-Carnitine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
[+]
Magnesium supplementation during cisplatin-containing chemotherapy was associated with less cisplatin-induced nephrotoxicity.
Apr 19, 2018
Click here to read the entire abstract
Pubmed Data
: J Pediatr Hematol Oncol. 2018 Apr 20. Epub 2018 Apr 20. PMID:
29683958
Article Published Date
: Apr 19, 2018
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Magnesium was found to provide nephroprotective effects among patients with cervical cancer undergoing chemotherapy with cisplatin alone.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2015 Apr ;35(4):2199-204. PMID:
25862878
Article Published Date
: Mar 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Cervical Cancer
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Manipulation of diet through high intake of yellow onion is a promising possibly to improve the synergistic effect in DOX-based chemotherapy.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2015 ;16(17):7517-22. PMID:
26625755
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Onion
Diseases
:
Breast Cancer
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Chemoprotective Agents
,
Chemotherapeutic
Additional Keywords
:
Dietary Modification
[+]
Memory deficits occur in breast cancer patients who receive either chemotherapy or tamoxifen.
Sep 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Psychosoc Oncol. 2011 Sep-Oct;29(5):499-514. PMID:
21882931
Article Published Date
: Sep 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity
,
Memory Disorders: Drug-Induced
,
Memory Loss
Anti Therapeutic Actions
:
Chemotherapy
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Neem oil and St. Johns Wort proved to be a safe and effective option in the management of acute skin toxicity in head and neck cancer patients.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Med Oncol. 2017 Feb ;34(2):30. Epub 2017 Jan 18. PMID:
28101834
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Neem
,
St. Johns Wort
Diseases
:
Chemotherapy and Radiation Toxicity
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Head and Neck Cancer
Pharmacological Actions
:
Chemoprotective Agents
,
Radioprotective
[+]
Oral cryotherapy prevents oral mucositis and pain among patients with colorectal cancer undergoing chemotherapy.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Clin J Oncol Nurs. 2018 10 1 ;22(5):555-560. PMID:
30239519
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Colorectal Cancer
,
Oral Mucositis
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Chemoprotective Agents
[+]
Oral glutamine supplementation protects lymphocytes and attenuates gut permeability in patients with esophageal cancer during radiochemotherapy.
Apr 01, 1998
Click here to read the entire abstract
Pubmed Data
: Ann Surg. 1998 Apr;227(4):485-91. PMID:
9563534
Article Published Date
: Apr 01, 1998
Study Type
: Human Study
Additional Links
Substances
:
Glutamine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Esophageal Cancer
,
Radiation Induced Illness
Additional Keywords
:
Drug: 5-flourouracil
,
Drug Side Effect Attenuation
[+]
Oral silymarin formulation efficacy in management of AC-T protocol induced hepatotoxicity in breast cancer patients.
Apr 15, 2021
Click here to read the entire abstract
Pubmed Data
: J Oncol Pharm Pract. 2021 Apr 16:10781552211006182. Epub 2021 Apr 16. PMID:
33861657
Article Published Date
: Apr 15, 2021
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Chemotherapy-Induced Toxicity: Doxorubicin
,
Chemotherapy-Induced Toxicity: Paclitaxel
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Chemotherapeutic
,
Hepatoprotective
[+]
Our results suggest that the Aronia extract supplementation in breast cancer patients has a beneficial effect on thiols concentration in plasma.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2013 Jan ;372(1-2):47-55. Epub 2012 Sep 5. PMID:
22949034
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Breast Cancer
,
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Drug: Doxorubicin
,
Plant Extracts
[+]
Palmitoylethanolamide restores myelinated-fibre function in patients with chemotherapy-induced painful neuropathy.
Nov 30, 2011
Click here to read the entire abstract
Pubmed Data
: CNS Neurol Disord Drug Targets. 2011 Dec ;10(8):916-20. PMID:
22229320
Article Published Date
: Nov 30, 2011
Study Type
: Human Study
Additional Links
Substances
:
Palmitoylethanolamide
Diseases
:
Chemotherapy-Induced Toxicity
,
Multiple Myeloma
Pharmacological Actions
:
Chemoprotective Agents
[+]
Polysaccharides isolated from Echinacea purpurea herba cell cultures to counteract undesired effects of chemotherapy.
Mar 01, 2002
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2002 Mar;16(2):138-42. PMID:
11933115
Article Published Date
: Mar 01, 2002
Study Type
: Human Study
Additional Links
Substances
:
Echinacea
Diseases
:
Chemotherapy-Induced Toxicity
,
Gastric Cancer
,
Leukopenia
,
Leukopenia: Chemotherapy Induced
Additional Keywords
:
Drug: 5-flourouracil
,
Plant Extracts
[+]
Propolis plus bicarbonate was safe, well tolerated and promisingly effective in the prevention of oral mucositis in patients with breast cancer.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Cancer Care (Engl). 2017 Nov ;26(6). Epub 2017 Aug 25. PMID:
28840622
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
,
Sodium Bicarbonate
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oral Mucositis
Pharmacological Actions
:
Chemoprotective Agents
[+]
Protective effects of Panax ginseng against doxorubicin-induced cardiac toxicity in patients with non-metastatic breast cancer.
Aug 16, 2022
Click here to read the entire abstract
Pubmed Data
: J Oncol Pharm Pract. 2022 Aug 17:10781552221118530. Epub 2022 Aug 17. PMID:
35975564
Article Published Date
: Aug 16, 2022
Study Type
: Human Study
Additional Links
Substances
:
Ginseng
Diseases
:
Breast Cancer
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Role of Mediterranean diet in preventing platinum based gastrointestinal toxicity in gynecolocological malignancies.
Dec 23, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Clin Oncol. 2019 Dec 24 ;10(12):391-401. PMID:
31890648
Article Published Date
: Dec 23, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy and Radiation Toxicity
,
Chemotherapy-Induced Toxicity: Cisplatin
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Chemoprotective Agents
,
Gastroprotective
[+]
Saccharomyces boulardii has significant therapeutic activity in irinotecan-induced (chemotherapy) diarrhea and mucositis.
Dec 09, 2008
Click here to read the entire abstract
Pubmed Data
: Med Oncol. 2008 Dec 9. PMID:
19067257
Article Published Date
: Dec 09, 2008
Study Type
: Human Study
Additional Links
Substances
:
Saccharomyces Boulardii
Diseases
:
Chemotherapy-Induced Toxicity
,
Diarrhea
,
Mucositis
Additional Keywords
:
Drug: Iriniotecan
[+]
Short term fasting during chemotherapy was well tolerated and reduced hematological toxicity of TAC in HER2-negative BC patients.
Oct 04, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Cancer. 2015 Oct 5 ;15:652. Epub 2015 Oct 5. PMID:
26438237
Article Published Date
: Oct 04, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer
,
Chemotherapy and Radiation Toxicity
,
Chemotherapy-Induced Toxicity: Doxorubicin
,
DNA damage
Therapeutic Actions
:
Fasting/Caloric Restriction
Pharmacological Actions
:
Chemotherapeutic
Additional Keywords
:
Risk Reduction
[+]
Somatostatin combined with melatonin, retinoids, vitamin D3, and low doses of cyclophosphamide led to an overall clinical benefit been achieved in 75% of cases.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Neuro Endocrinol Lett. 2013 ;34(7):660-8. PMID:
24464005
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
,
Vitamin D
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
,
Chemotherapy-Induced Toxicity: Cyclophosphamide
Additional Keywords
:
Natural Substance/Drug Synergy
,
Significant Treatment Outcome
[+]
Soy isoflavones ameliorate the adverse effects of chemotherapy in children.
Oct 01, 1996
Click here to read the entire abstract
Pubmed Data
: J Infect Dis. 1996 Oct;174(4):747-51. PMID:
20924976
Article Published Date
: Oct 01, 1996
Study Type
: Human Study
Additional Links
Substances
:
Genistein
,
Isoflavones
Diseases
:
Chemotherapy Induced Myelotoxicity
[+]
The cisplatin total dose had a significant negative relationship with magnesium levels at 12 months in this study.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Medicine (Baltimore). 2015 Aug ;94(34):e1413. PMID:
26313789
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Magnesium Deficiency
Problem Substances
:
Cisplatin
[+]
The decrease in neutrophil count caused by breast carcinoma chemotherapy was ameliorated by dietary supplementation with a multivitamin or vitamin E.
Sep 01, 2004
Click here to read the entire abstract
Pubmed Data
: Cancer. 2004 Sep 1;101(5):1058-64. PMID:
15329916
Article Published Date
: Sep 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
,
Vitamin B-12
,
Vitamin E
Diseases
:
Breast Cancer
,
Chemotherapy Induced Myelotoxicity
,
Chemotherapy-Induced Toxicity
,
Mucositis
,
Neutropenia: Chemotherapy Induced
Pharmacological Actions
:
Antineoplastic Agents
,
Antioxidants
[+]
Therapy-related acute myeloid leukemia and myelodysplastic syndrome has been reported.
Sep 01, 2005
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2005 Fall;8(3):382-5. PMID:
3857944
Article Published Date
: Sep 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Leukemia: Acute myelogenous leukemia (AML)
,
Lymphoma
,
Myelodysplastic Syndrome
,
Radiation Induced Illness
Additional Keywords
:
Iatrogenic Disease
Anti Therapeutic Actions
:
Chemotherapy
,
Radiotherapy
[+]
These results demonstrated the feasibility of a dietary antioxidant supplementation in order to prevent the cisplatin induced hearing damage.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2017 Feb ;3(2):e00251. Epub 2017 Feb 20. PMID:
28239674
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
,
Multivitamin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
TRAUMEEL S may reduce significantly the severity and duration of chemotherapy-induced stomatitis in children undergoing bone marrow transplantation.
Aug 01, 2001
Click here to read the entire abstract
Pubmed Data
: Cancer. 2001 Aug 1;92(3):684-90. PMID:
11505416
Article Published Date
: Aug 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Homeopathic Medicine: Traumeel
Diseases
:
Chemotherapy-Induced Toxicity
,
Stomatitis: Chemotherapy-Induced
Therapeutic Actions
:
Homeopathic Treatment
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Vitamin E and N-acetylcysteine are an effective antioxidant adjuvant therapy in children with acute lymphoblastic leukemia to reduce the chemo-/radiotherapy toxicity of treatment.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Adv Hematol. 2009;2009:689639. Epub 2009 Oct 20. PMID:
19960046
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
,
Vitamin E
Diseases
:
Acute lymphoblastic leukemia (ALL)
,
Chemotherapy-Induced Toxicity
,
Radiation Induced Illness
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Drug Side Effect Attenuation
[+]
Wheat grass juice may reduce myelotoxicity and need for granulocyte colony-stimulating factors in breast cancer patients receiving chemotherapy.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2007;58(1):43-8. PMID:
17571966
Article Published Date
: Jan 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Wheat Grass
Diseases
:
Breast Cancer
,
Chemotherapy Induced Myelotoxicity
,
Chemotherapy-Induced Toxicity
,
Myelotoxicity
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
Glycine max and Chrysanthemum indicum extracts exhibited a promising protective effect on cisplatin-induced nephrotoxicity.
Nov 30, 2011
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2011 Dec ;30(12):1931-44. Epub 2011 Mar 15. PMID:
21406484
Article Published Date
: Nov 30, 2011
Study Type
: Human In Vitro
Additional Links
Substances
:
Chrysanthemum Indicum
,
Soy
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Onion extract may have protective effects against BLM-induced cyto- and genotoxicity in human lymphocytes.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2016 ;13(2). Epub 2016 Feb 19. PMID:
26907305
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Onion
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Chemoprotective Agents
Additional Keywords
:
Plant Extracts
Problem Substances
:
Bleomycin
[+]
Protective effects of crocetin on arsenic trioxide-induced oxidative stress.
Oct 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: In Vivo. 2021 Nov-Dec;35(6):3157-3163. PMID:
34697146
Article Published Date
: Oct 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Crocetin
Diseases
:
Chemotherapy-Induced Toxicity: Arsenic Trioxide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Chemoprotective Agents
Problem Substances
:
Arsenic Trioxide
[+]
Self-assembled betulinic acid can be used to ameliorate the cytotoxic effects of Doxorubicin.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2015 May ;72:144-57. Epub 2015 Apr 24. PMID:
26054689
Article Published Date
: Apr 30, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Betulinic acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Chemoprotective Agents
[+]
These findings indicate that the protective effects of low-dose BBR against DOX-induced cardiotoxicity are mediated by Bcl-xL.
Apr 29, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 Apr 30 ;101:154130. Epub 2022 Apr 30. PMID:
35526324
Article Published Date
: Apr 29, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
This study demonstrates that sulforaphane targets multiple signaling pathways to suppress ovarian cancer in vitro and in vivo.
Nov 01, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2018 Nov ;42(5):2447-2458. Epub 2018 Sep 6. PMID:
30226534
Article Published Date
: Nov 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Female
,
Ovarian Cancer
Pharmacological Actions
:
Anti-Tumor
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
HER-2 oncoprotein down-regulation
,
NF-kappaB Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Drug Synergy
,
Isothiocyanates
[+]
Baicalein enhances the expansion of hematopoietic and progenitor stem cells and alleviates 5-fluorouracil-induced myelosuppression.
Feb 02, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Feb 3 ;24(3). Epub 2023 Feb 3. PMID:
36769312
Article Published Date
: Feb 02, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Chemoprotective Agents
[+]
Capsaicin alleviates cisplatin-induced muscle loss and atrophy in vitro and in vivo.
Nov 17, 2022
Click here to read the entire abstract
Pubmed Data
: J Cachexia Sarcopenia Muscle. 2022 Nov 18. Epub 2022 Nov 18. PMID:
36401337
Article Published Date
: Nov 17, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Cachexia: Chemotherapy Induced
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Cachexic Agents
,
Chemoprotective Agents
[+]
Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis.
Apr 30, 2022
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2022 May ;45(3):1264-1275. Epub 2020 Sep 14. PMID:
32924642
Article Published Date
: Apr 30, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Anti-Fibrotic
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Hyperbaric oxygen as a treatment modality in cyclophosphamide-induced hemorrhagic cystitis.
Mar 22, 2018
Click here to read the entire abstract
Pubmed Data
: Pediatr Transplant. 2018 Mar 23:e13171. Epub 2018 Mar 23. PMID:
29569791
Article Published Date
: Mar 22, 2018
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Chemoprotective Agents
[+]
Icariin exhibits protective effects on cisplatin-induced cardiotoxicity.
Aug 31, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 Sep ;104:154331. Epub 2022 Jul 10. PMID:
35878553
Article Published Date
: Aug 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Icariin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
In vitro and in vivo nephroprotective effects of Nelumbo nucifera seedpod extract against cisplatin-induced renal injury.
Dec 01, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Plants (Basel). 2022 Dec 2 ;11(23). Epub 2022 Dec 2. PMID:
36501396
Article Published Date
: Dec 01, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lotus
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
Induction of P-glycoprotein expression by dandelion in tumor and heart tissues: Impact on the anti-tumor activity and cardiotoxicity of doxorubicin.
Jun 11, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 Jun 12 ;104:154275. Epub 2022 Jun 12. PMID:
35760022
Article Published Date
: Jun 11, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Dandelion
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress.
Jan 31, 2022
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2022 Feb ;56(2):209-221. Epub 2022 Apr 25. PMID:
35468014
Article Published Date
: Jan 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Luteolin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Myricetin-loaded nanomicelles protect against cisplatin-induced acute kidney injury.
Nov 02, 2022
Click here to read the entire abstract
Pubmed Data
: Mol Pharm. 2022 Nov 3. Epub 2022 Nov 3. PMID:
36326450
Article Published Date
: Nov 02, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Myricetin
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Natural compound glycyrrhetinic acid protects against doxorubicin-induced cardiotoxicity.
Sep 03, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 Sep 4 ;106:154407. Epub 2022 Sep 4. PMID:
36070662
Article Published Date
: Sep 03, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
18β-Glycyrrhetinic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Nrf2 activation
[+]
Nuciferine attenuates doxorubicin-induced cardiotoxicity.
Jan 10, 2021
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Toxicol. 2021 11 ;21(11):947-963. Epub 2021 Aug 16. PMID:
34401977
Article Published Date
: Jan 10, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lotus
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
[+]
Protective effects of liquiritigenin against cisplatin-induced nephrotoxicity.
Jun 13, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Jun 14 ;27(12). Epub 2022 Jun 14. PMID:
35744945
Article Published Date
: Jun 13, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Licorice
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Puerarin activates adaptive autophagy and protects the myocardium against doxorubicin-induced cardiotoxicity.
Aug 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Sep ;153:113403. Epub 2022 Jul 13. PMID:
36076529
Article Published Date
: Aug 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Puerarin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity.
Dec 25, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Immunopharmacol. 2022 Dec 26 ;115:109635. Epub 2022 Dec 26. PMID:
36580758
Article Published Date
: Dec 25, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcuminoids
Diseases
:
Cancers: All
,
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Coronavirus Infection
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
[+]
Tanshinone IIA inhibits cardiomyocyte apoptosis and rescues cardiac function during doxorubicin-induced cardiotoxicity.
Sep 20, 2022
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2022 Sep 21 ;107:154471. Epub 2022 Sep 21. PMID:
36182795
Article Published Date
: Sep 20, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines.
Aug 17, 2020
Click here to read the entire abstract
Pubmed Data
: Cancer Chemother Pharmacol. 2020 Aug 18. Epub 2020 Aug 18. PMID:
32812061
Article Published Date
: Aug 17, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Protective effects of rosmarinic acid on doxorubicin-induced testicular damage.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Chemotherapy. 2014 ;60(1):7-12. Epub 2014 Oct 4. PMID:
25301265
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Rosmarinic acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oxidative Stress
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Malondialdehyde Down-regulation
[+]
Protective role of chrysin on doxorubicin-induced oxidative stress and DNA damage in rat testes.
Jul 15, 2020
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2020 Jul 16:e13747. Epub 2020 Jul 16. PMID:
32672853
Article Published Date
: Jul 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
DNA damage
,
Oxidative Stress
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Chemoprotective Agents
[+]
The efficiency of blackberry loaded AgNPs, AuNPs and
[email protected]
mediated pectin in the treatment of cisplatin-induced cardiotoxicity.
May 19, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2020 May 20 ;159:1084-1093. Epub 2020 May 20. PMID:
32442568
Article Published Date
: May 19, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Blackberry
,
Gold (nanoparticles)
,
Silver (nanoparticles)
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
The nephroprotective effects of Daucus carota and Eclipta prostrata against cisplatin-induced nephrotoxicity in rats.
Jan 11, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Bioengineered. 2021 12 ;12(2):12702-12721. PMID:
34949157
Article Published Date
: Jan 11, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Carrots
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Renoprotective
[+]
The protective effects of hesperidin and curcumin on 5-fluorouracil-induced nephrotoxicity.
Apr 21, 2021
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2021 Apr 22. Epub 2021 Apr 22. PMID:
33886055
Article Published Date
: Apr 21, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Hesperidin
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Thymoquinone ameliorates bleomycin-induced reproductive toxicity in male Balb/c mice.
Nov 23, 2021
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2021 Nov 24:9603271211048184. Epub 2021 Nov 24. PMID:
34818114
Article Published Date
: Nov 23, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Chemoprotective Agents
[+]
"Curcumin ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in mice."
Dec 11, 2012
Click here to read the entire abstract
Pubmed Data
: J Biosci Bioeng. 2012 Dec 12. Epub 2012 Dec 12. PMID:
23245727
Article Published Date
: Dec 11, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Chemotherapy-Induced Toxicity: Kidney
Pharmacological Actions
:
Renoprotective
Additional Keywords
:
Drug: Cisplatin
[+]
"Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy."
Feb 14, 2012
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2012 Feb 14. Epub 2012 Feb 14. PMID:
22338017
Article Published Date
: Feb 14, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Injury: Hippocampal Damage
,
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Doxorubicin
,
Cognitive Decline/Dysfunction
Additional Keywords
:
Drug: Doxorubicin
Anti Therapeutic Actions
:
Chemotherapy
Problem Substances
:
Cyclophosphamide
,
Doxorubicin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
2,3,5,4'-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Toxicol. 2018 Jan ;33(1):72-82. Epub 2017 Oct 24. PMID:
29064158
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Nrf2 activation
[+]
20(S)-ginsenoside Rg(3) showed the significant protective effects on cyclophosphamide-induced cell DNA damage and apoptosis.
Jan 31, 2008
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2008 Feb ;82(2):117-23. Epub 2007 Jun 28. PMID:
17598087
Article Published Date
: Jan 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
5-FU was found to induce a reduction in food intake in mice.
Apr 29, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2016 Apr 30. Epub 2016 Apr 30. PMID:
27130783
Article Published Date
: Apr 29, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Anorexia: Cancer-Associated
,
Cachexia: Chemotherapy Induced
,
Chemotherapy-Induced Toxicity: 5-fluorouracil
Problem Substances
:
Fluorouracil (5-FU or f5U)
[+]
6-gingerol ameliorates cisplatin-induced pica.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2020 ;14:4085-4099. Epub 2020 Oct 2. PMID:
33061309
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
6-gingerol was as effective as ondansetron in the treatment of pica induced by cisplatin.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2019 ;13:2633-2641. Epub 2019 Aug 1. PMID:
31534312
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Pica Syndrome
Pharmacological Actions
:
Chemoprotective Agents
,
Gastrointestinal Agents
,
Gastroprotective
Additional Keywords
:
Natural Substances Versus Drugs
[+]
A Chinese herbal formula containing Red Sage, Cordyceps and Peach kernel is superior to methylprednisone against experimental pulmonary fibrosis.
May 01, 2007
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2007 May;32(9):835-9. PMID:
17639988
Article Published Date
: May 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Red Sage
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
A combination of Bacopa, Amla (E. officinalis), Licorice (G. glabra), Indian mango (M. indica) and Clove (S. aromaticum) protect against experimentally-induced cardiac and renal damage.
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2005 Mar;19(3):216-21. PMID:
15934019
Article Published Date
: Mar 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Amla Fruit
,
Bacopa
,
Clove
,
Licorice
,
Mango
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
A combination of curcumin with piperine exhibited profound cardioprotection compared to curcumin alone-treated group.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Indian J Pharmacol. 2017 Jan-Feb;49(1):65-70. PMID:
28458425
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Piperine
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
A combination of virgin coconut oil and extra virgin olive oil elicits superior protection against doxorubicin cardiotoxicity in rats.
Jan 28, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Pharm Sci. 2022 04 29 ;19(2):138-144. PMID:
35509244
Article Published Date
: Jan 28, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Coconut
,
Olive Oil
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
Additional Keywords
:
Natural Substance Synergy
[+]
A compound in ginger known as 6-Gingerol prevents cisplatin-induced acute renal failure in rats.
Apr 06, 2005
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2005 Apr 6;53(7):2446-50. PMID:
16971750
Article Published Date
: Apr 06, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Catechols
,
Ginger
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Antineoplastic Agents
,
Renoprotective
[+]
A compound in mangosteen prevents cisplatin-induced toxicity to the kidneys of rats.
Oct 06, 2010
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Oct 6;188(1):144-50. PMID:
20603111
Article Published Date
: Oct 06, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Mangosteen
Diseases
:
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Renoprotective
Additional Keywords
:
Drug Side Effect Attenuation
[+]
A diet supplemented with whole Chlorella vulgaris has beneficial effects on cyclophosphamide induced immunosuppression.
Jul 05, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Jul 6 ;9(7). Epub 2017 Jul 6. PMID:
28684674
Article Published Date
: Jul 05, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Immunomodulatory
[+]
A enriched extract of blueberry anthocyanins protected against cyclophosphamide induced lung damage.
Oct 15, 2014
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2014 Oct 16 ;222C:106-111. Epub 2014 Oct 16. PMID:
25451569
Article Published Date
: Oct 15, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Dose Response
[+]
A methanolic extract of Nettle has a protective capacity and antioxidant activity against cisplatin toxicity.
Jun 30, 2012
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2012 Jul ;35(3):251-7. Epub 2011 Sep 22. PMID:
21939360
Article Published Date
: Jun 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Nettle
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
Additional Keywords
:
Plant Extracts
[+]
A Panax quinquefolius-based preparation prevents the impact of 5-FU on activity/exploration behaviors.
Sep 09, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2022 Sep 10 ;14(18). Epub 2022 Sep 10. PMID:
36139563
Article Published Date
: Sep 09, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (American)
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Neuroprotective Agents
[+]
A polysaccharide from natural Cordyceps sinensis regulates the intestinal immunity and gut microbiota in mice with cyclophosphamide-induced intestinal injury.
Jun 07, 2021
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2021 Jun 8. Epub 2021 Jun 8. PMID:
34105571
Article Published Date
: Jun 07, 2021
Study Type
: Animal Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Gastroprotective
,
Immunomodulatory
Additional Keywords
:
Polysaccharides
[+]
A purified dry extract of ginseng may improve cancer related fatigue via regulation of inflammatory responses and hematopoiesis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:197459. Epub 2015 Apr 7. PMID:
25945105
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Fatigue: Cancer-Associated
Pharmacological Actions
:
Chemoprotective Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A reishi extract ameliorates the colon precancerous lesions induced by AOM and the small-intestinal injury caused by 5-FU.
May 31, 2013
Click here to read the entire abstract
Pubmed Data
: Med Mol Morphol. 2013 Jun ;46(2):97-103. Epub 2013 Jan 22. PMID:
23338779
Article Published Date
: May 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemoprotective Agents
[+]
Administration of a probiotic mixture ameliorates cisplatin-induced mucositis and pica by regulating 5-HT in rats.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Immunol Res. 2021 ;2021:9321196. Epub 2021 Sep 14. PMID:
34568500
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Probiotics
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Administration of M. vulgare extract was found to be beneficial by attenuating cyclophosphamide-induced liver damage.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 Apr ;94(4):441-7. Epub 2015 Oct 28. PMID:
26886858
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Horehound
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Administration of Moringa oleifera extract mitigated cyclophosphamide-induced testicular damage.
May 14, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 May 15:112922. Epub 2020 May 15. PMID:
32422360
Article Published Date
: May 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Chemoprotective Agents
Additional Keywords
:
Gene Expression Regulation
[+]
Administration of parsley oil either as a preventative medicine or as treatment significantly improved cisplatin-induced hepato-cardiotoxicity.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Feb ;86:482-491. Epub 2016 Dec 23. PMID:
28012928
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Parsley
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
Additional Keywords
:
Plant Oils
[+]
Administration of Zataria multiflora extract and carvacrol could reduce the oxidative damage in the rat liver induced by doxorubicin.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed J. 2018 Dec ;41(6):340-347. Epub 2019 Jan 11. PMID:
30709575
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
,
Zataria multiflora
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Aerobic exercise may reduce cisplatin-induced nephrotoxicity with a favorable effect on renal function by increasing activation of antioxidant system.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian J Sports Med. 2015 Sep ;6(3):e24901. Epub 2015 Sep 28. PMID:
26448855
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
AGE has an ameliorative effect against CP-induced oxidative stress and renal damage through its antioxidant, anti-inflammatory and antiapoptotic properties.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell Int. 2014 ;14(1):92. Epub 2014 Sep 28. PMID:
25298749
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Aged garlic extract and grape seed proanthocyanidin protect against doxorubicin-induced cardiotoxicity.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2009 Aug;87(8):633-40. PMID:
19767888
Article Published Date
: Aug 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
,
Grape Seed Extract
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Drug: Doxorubicin
,
Plant Extracts
,
Proanthocyanidins
[+]
Aged garlic extract exhibited antioxidant effect that could ameliorate the nephrotoxic effects of cisplatin.
Mar 21, 2015
Click here to read the entire abstract
Pubmed Data
: Microsc Res Tech. 2015 Mar 22. Epub 2015 Mar 22. PMID:
25810378
Article Published Date
: Mar 21, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
[+]
Aged garlic extract protects against doxorubicin-induced cardiotoxicity in rats.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2006 Feb;22(2):136-45. PMID:
20060872
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Drug Side Effect Attenuation
[+]
AHCC attenuates cisplatin (chemotherapy) induced side effects in tumor-bearing mice.
Jul 15, 2007
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2007 Jul 15;222(2):152-8. Epub 2007 Apr 20. PMID:
17555784
Article Published Date
: Jul 15, 2007
Study Type
: Animal Study
Additional Links
Substances
:
AHCC
Diseases
:
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Tumors
[+]
AHCC improves treatment outcome and reduces side effects in anticancer drug treated mice.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Exp Ther Oncol. 2009;8(1):43-51. PMID:
19827270
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
AHCC
Diseases
:
Cancers: Multi-Drug Resistant
,
Chemotherapy Induced Myelotoxicity
,
Chemotherapy-Induced Toxicity
,
Myelotoxicity
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
AHCC prevents chemotherapy induced hair loss.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol. 2009 Oct;33(3-4):293-9. Epub 2009 Aug 20. PMID:
19699163
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
AHCC
Diseases
:
Chemotherapy-Induced Toxicity
,
Hair Loss
[+]
Ajwa dates attenuate cisplatin-induced nephrotoxicity.
Nov 30, 2022
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2022 Dec ;156:113836. Epub 2022 Oct 12. PMID:
36242846
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Ajwa nanopreparation prevents doxorubicin-associated cardiac dysfunction.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Cancer Ther. 2019 Jan-Dec;18:1534735419862351. PMID:
31282195
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Alginate oligosaccharide alleviated cisplatin-induced kidney oxidative stress.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Immunol. 2022 ;13:857242. Epub 2022 Apr 1. PMID:
35432359
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus reuteri
,
Oligosaccharides
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Alleviating chronic kidney disease progression through modulating the critical genus of gut microbiota in a cisplatin-induced Lanyu pig model.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Food Drug Anal. 2020 Jan ;28(1):103-114. Epub 2019 Oct 17. PMID:
31883598
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus paracasei
,
Lactobacillus plantarum
,
Probiotics
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Renoprotective
[+]
Alleviation of cyclophosphamide-induced hemorrhagic cystitis by dietary pomegranate.
May 03, 2018
Click here to read the entire abstract
Pubmed Data
: J Pediatr Hematol Oncol. 2018 May 4. Epub 2018 May 4. PMID:
29734214
Article Published Date
: May 03, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Cystitis: Hemorrhagic
Pharmacological Actions
:
Chemoprotective Agents
[+]
Alleviative effects of astragaloside IV on cyclophosphamide-induced oxidative damage and immunosuppression.
Nov 07, 2022
Click here to read the entire abstract
Pubmed Data
: Comp Biochem Physiol C Toxicol Pharmacol. 2022 Nov 8:109503. Epub 2022 Nov 8. PMID:
36368505
Article Published Date
: Nov 07, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Heme oxygenase-1 up-regulation
,
Immunomodulatory
,
Nrf2 activation
Problem Substances
:
Cyclophosphamide
[+]
Allicin could be a promising cytoprotective agent against doxorubicin cardiotoxicity.
Aug 06, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Chemother Pharmacol. 2017 Aug 7. Epub 2017 Aug 7. PMID:
28785995
Article Published Date
: Aug 06, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Garlic
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Allicin may be useful in preventing cisplatin-induced ototoxicity.
Jul 23, 2019
Click here to read the entire abstract
Pubmed Data
: ORL J Otorhinolaryngol Relat Spec. 2019 Jul 24:1-13. Epub 2019 Jul 24. PMID:
31340214
Article Published Date
: Jul 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Allicin may be useful in preventing oto-vestibulotoxicity mediated by cisplatin.
Jun 14, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Jun 15 ;805:108-117. Epub 2017 Mar 1. PMID:
28259711
Article Published Date
: Jun 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Allicin mitigates hepatic injury following cyclophosphamide administration.
Mar 23, 2021
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2021 Mar 24. Epub 2021 Mar 24. PMID:
33763830
Article Published Date
: Mar 23, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Hepatoprotective
,
Nrf2 activation
[+]
Allicin protects auditory hair cells and spiral ganglion neurons from cisplatin.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2017 Apr ;116:429-440. Epub 2017 Jan 3. PMID:
28062185
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Alpha lipoic acid attenuates bleomycin-induced pulmonary fibrosis in mice.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2007 Jun;19(6):865-73. PMID:
17487418
Article Published Date
: Jun 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Pulmonary Fibrosis
[+]
Alpha lipoic acid attenuates cisplatin-induced acute kidney injury in mice by suppressing renal inflammation.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nephrol Dial Transplant. 2009 Oct;24(10):3012-20. Epub 2009 May 27. PMID:
19474282
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Alpha lipoic acid has a therapeutic role in ameliorating DOX-induced testicular damage.
Mar 31, 2021
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2021 Apr ;53(3):e13990. Epub 2021 Feb 2. PMID:
33529370
Article Published Date
: Mar 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
[+]
Amelioration of bleomycin and methotrexate-induced pulmonary toxicity by serratiopeptidase and fisetin.
Dec 22, 2020
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2020 Dec 23:1-10. Epub 2020 Dec 23. PMID:
33353415
Article Published Date
: Dec 22, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Drug-Induced Toxicity: Methotrexate
Pharmacological Actions
:
Chemoprotective Agents
[+]
Amelioration of bleomycin induced pulmonary fibrosis by administration of Salvianolic acid B.
Nov 17, 2022
Click here to read the entire abstract
Pubmed Data
: Vet Ital. 2022 Nov 18 ;58(1):87-101. Epub 2022 Nov 18. PMID:
36398675
Article Published Date
: Nov 17, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Anti-Fibrotic
,
Chemoprotective Agents
[+]
Amelioration of chemotherapy-induced intestinal mucositis by orally administered probiotics.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(9):e0138746. Epub 2015 Sep 25. PMID:
26406888
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Probiotics
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Diarrhea: Drug-Associated
,
Mucositis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Gastroprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Amelioration of cisplatin-induced nephrotoxicity in rats by triterpenoid saponin of Terminalia arjuna.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Clin Exp Nephrol. 2015 Aug ;19(4):591-7. Epub 2014 Nov 12. PMID:
25389052
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Terminalia
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Amelioration of cyclophosphamide toxicity via modulation of metabolizing enzymes by avocado (Persea americana) extract.
Mar 02, 2022
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2022 Mar 3 ;74(3):367-376. PMID:
34173661
Article Published Date
: Mar 02, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Avocado
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Amelioration of the cyclophosphamide induced genotoxic damage in mice by the ethanolic extract of Equisetum arvense.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Rep. 2017 ;4:226-233. Epub 2017 May 11. PMID:
28959643
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Horsetail
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ameliorative effect of Atractylodes macrocephala essential oil combined with Panax ginseng total saponins on 5-fluorouracil induced diarrhea.
Jun 27, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Jun 28 ;238:111887. Epub 2019 Apr 17. PMID:
31004726
Article Published Date
: Jun 27, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bai Zhu
,
Ginseng
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Diarrhea: Drug-Associated
,
Dysbiosis
Pharmacological Actions
:
Chemoprotective Agents
,
Gastrointestinal Agents
Additional Keywords
:
Essential Oils
[+]
Ameliorative effect of betanin on experimental cisplatin-induced liver injury.
Mar 03, 2021
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2021 Mar 4:e22753. Epub 2021 Mar 4. PMID:
33661552
Article Published Date
: Mar 03, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Betanin
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2020 Dec ;22(6):5271-5281. Epub 2020 Oct 14. PMID:
33173984
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocetin
Diseases
:
Arsenic Poisoning
,
Chemotherapy-Induced Toxicity: Arsenic Trioxide
,
Leukemia: Acute promyelocytic leukemia
Pharmacological Actions
:
Cardioprotective
Problem Substances
:
Arsenic Trioxide
[+]
Ameliorative effects of arctigenin on pulmonary fibrosis induced by bleomycin via the antioxidant activity.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2022 ;2022:3541731. Epub 2022 Jul 5. PMID:
35847593
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Chemoprotective Agents
[+]
Ameliorative effects of gallic acid on cisplatin-induced nephrotoxicity.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2021 ;2021:2195238. Epub 2021 Oct 26. PMID:
34746299
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gallic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
An enriched blueberry anthocyanin extract attenuated the cyclophosphamide induced cardiac injury.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: PLoS One. 2015 ;10(7):e0127813. Epub 2015 Jul 2. PMID:
26133371
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
Additional Keywords
:
Significant Treatment Outcome
[+]
An extract of Mandarin Orange demonstrates anti-pulmonary fibrosis effects.
Oct 29, 2009
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2009 Oct 29;126(1):143-8. Epub 2009 Jul 28. PMID:
19643175
Article Published Date
: Oct 29, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Orange: Mandarin
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Pulmonary Fibrosis
[+]
An extract of Moringa oleifera leaves could protect the spermatogonial cells from cyclophosphamide induced damage.
Apr 21, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Apr 22 ;182:101-9. Epub 2016 Feb 10. PMID:
26875643
Article Published Date
: Apr 21, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Chemoprotective Agents
,
Fertility Agents: Male
Additional Keywords
:
Plant Extracts
Problem Substances
:
Cyclophosphamide
[+]
An extract of P. oleracea leaves ameliorated the immunosuppressive action of cyclophosphamide in mice.
Apr 05, 2018
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 Apr 6 ;215:191-198. Epub 2018 Jan 9. PMID:
29325915
Article Published Date
: Apr 05, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Purslane
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Antispasmodic
,
Immunomodulatory
Problem Substances
:
Cyclophosphamide
[+]
An extract of Zataria multiflora and carvacrol had protective effects on the renal damage induced by Adriamycin.
Aug 08, 2019
Click here to read the entire abstract
Pubmed Data
: Arch Physiol Biochem. 2019 Aug 9:1-9. Epub 2019 Aug 9. PMID:
31397187
Article Published Date
: Aug 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
,
Zataria multiflora
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Malondialdehyde Down-regulation
,
Renoprotective
[+]
Annato seed extracts could prevent oxidative stress that is occasioned by cyclophosphamide administration.
Feb 28, 2011
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2011 Mar ;63(3):257-62. PMID:
20137904
Article Published Date
: Feb 28, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Achiote
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins from purple sweet potato alleviate doxorubicin-induced cardiotoxicity in vitro and in vivo.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2021 09 ;45(9):e13869. Epub 2021 Jul 19. PMID:
34287964
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Sweet Potato: Purple
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Infect Chemother. 2016 Jan ;22(1):36-43. Epub 2015 Nov 19. PMID:
26603425
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Indole-3-Carbinol
Diseases
:
Breast Cancer
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Anti-oxidant effect of bergamot polyphenolic fraction counteracts doxorubicin-induced cardiomyopathy.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Mol Cell Cardiol. 2018 Jun ;119:10-18. Epub 2018 Apr 12. PMID:
29654879
Article Published Date
: May 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Antiallodynic effect of intrathecal Korean red ginseng in cisplatin-induced neuropathic pain rats.
Oct 01, 2019
Click here to read the entire abstract
Pubmed Data
: Pharmacology. 2019 Oct 2:1-8. Epub 2019 Oct 2. PMID:
31578020
Article Published Date
: Oct 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Allodynia
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Antifibrotic mechanism of piceatannol in bleomycin-induced pulmonary fibrosis in mice.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:771031. Epub 2022 Jun 7. PMID:
35747752
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Piceatannol
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Anti-Fibrotic
,
Chemoprotective Agents
[+]
Antimutagenic activity of ipriflavone against the DNA-damage induced by cyclophosphamide.
Feb 28, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Chem Toxicol. 2014 Mar ;65:140-6. Epub 2013 Dec 31. PMID:
24389340
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ipriflavone
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
DNA damage
Pharmacological Actions
:
Antimutagenic Agents
,
Chemoprotective Agents
[+]
Antioxidant and anti-inflammatory effects of crocin ameliorate doxorubicin-induced nephrotoxicity.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2021 ;2021:8841726. Epub 2021 Feb 15. PMID:
33628387
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Antioxidant effect of acetyl-l-carnitine against cisplatin-induced cardiotoxicity.
Jul 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Int Med Res. 2020 Aug ;48(8):300060520951393. PMID:
32865065
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
L-Carnitine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
[+]
Antioxidant, antiapoptotic, and antifibrotic effects of the combination of liposomal resveratrol and carvedilol against doxorubicin-induced cardiomyopathy.
Mar 14, 2020
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2020 Mar 15:e22492. Epub 2020 Mar 15. PMID:
32173980
Article Published Date
: Mar 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Apigenin and myricetin exhibited a protective and promising preventive strategy against cisplatin-induced nephrotoxicity.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):766-774. PMID:
28064632
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Myricetin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Chemoprotective Agents
,
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin attenuates doxorubicin induced cardiotoxicity via reducing oxidative stress and apoptosis.
Jul 03, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Jul 4:116623. Epub 2019 Jul 4. PMID:
31279781
Article Published Date
: Jul 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
[+]
Apigenin may have a protective effect against Adriamycin induced cardiotoxicity.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2017 ;2017:2590676. Epub 2017 Jun 8. PMID:
28684964
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Chemotherapy-Induced Toxicity: Adriamycin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Apricot Kernel Oil Ameliorates Cyclophosphamide-Associated Immunosuppression in Rats.
Jun 03, 2016
Click here to read the entire abstract
Pubmed Data
: Lipids. 2016 Jun 4. Epub 2016 Jun 4. PMID:
27262314
Article Published Date
: Jun 03, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apricot Kernel
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Problem Substances
:
Cyclophosphamide
[+]
Arsenicum Album 6C and 30C remedies indicated potentials of use against arsenic intoxication.
Dec 31, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pathobiology. 2008 ;75(3):156-70. PMID:
18550913
Article Published Date
: Dec 31, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Homeopathic Arsenicum album
Diseases
:
Chemotherapy-Induced Toxicity: Arsenic Trioxide
Pharmacological Actions
:
Chemoprotective Agents
[+]
Artemisinin attenuates doxorubicin induced cardiotoxicity and hepatotoxicity.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2020 Feb ;95(2):121-128. Epub 2019 Sep 6. PMID:
32064961
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Artemisinin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ascorbic acid and vitamin E protect against cisplatin induced kidney injury in mice.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Clin Chim Acta. 2007 Jan;375(1-2):82-6. Epub 2006 Jun 14. PMID:
16889761
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
,
Vitamin E
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
[+]
Ascorbic acid may attenuate cisplatin-induced nephrotoxicity and reverse P-gp-mediated changes in drug pharmacokinetics.
Jul 28, 2021
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2021 Jul 29 ;909:174395. Epub 2021 Jul 29. PMID:
34332922
Article Published Date
: Jul 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
Asiatic acid ameliorates doxorubicin-induced cardiac and hepato-renal toxicities.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Cardiovasc Toxicol. 2018 Apr ;18(2):131-141. PMID:
28856520
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Hepatoprotective
,
Nrf2 activation
[+]
Asiatic acid can prevent the spatial working memory and hippocampal neurogenesis impairments caused by 5-FU chemotherapy.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(7):e0180650. Epub 2017 Jul 10. PMID:
28700628
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Asiatic acid has neuroprotective properties against 5-fluorouracil chemotherapy.
Aug 08, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Aug 9 ;10(8). Epub 2018 Aug 9. PMID:
30096914
Article Published Date
: Aug 08, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Asiatic acid might be an effective candidate for pulmonary fibrosis and inflammation treatment.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 May ;89:1297-1309. Epub 2017 Mar 17. PMID:
28320097
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Inflammation
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
[+]
Asiatic acid protects against cisplatin-induced acute kidney injury via anti-apoptosis and anti-inflammation.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Nov ;107:1354-1362. Epub 2018 Aug 30. PMID:
30257350
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Chemoprotective Agents
[+]
Asiatic acid protects against doxorubicin-induced cardiotoxicity.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2020 ;2020:5347204. Epub 2020 May 15. PMID:
32509145
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Astaxanthin enhances the intestinal mucosal functions in immunodeficient mice.
Mar 30, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Mar 31. Epub 2020 Mar 31. PMID:
32232254
Article Published Date
: Mar 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Gastroprotective
,
Immunomodulatory
[+]
Astaxanthin from haematococcus pluvialis ameliorates the chemotherapeutic drug doxorubicin induced liver injury.
May 13, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 May 14. Epub 2020 May 14. PMID:
32405635
Article Published Date
: May 13, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Nrf2 activation
[+]
Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2010 Feb ;696(1):69-80. Epub 2009 Dec 28. PMID:
20038455
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
DNA damage
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Chemopreventive
,
Tumor Suppressor Protein p53 Upregulation
[+]
Astaxanthin may have protective effect against cisplatin-induced ototoxicity.
Sep 25, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ear Nose Throat J. 2019 Sep 26:145561319866826. Epub 2019 Sep 26. PMID:
31558064
Article Published Date
: Sep 25, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Astaxanthin protects against cyclophosphamide cardiotoxicity.
Sep 30, 2021
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2021 Oct 1. Epub 2021 Oct 1. PMID:
34597426
Article Published Date
: Sep 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Astaxanthin protects against cyclophosphamide-induced oxidative stress and DNA damage.
Aug 14, 2009
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2009 Aug 14;180(3):398-406. Epub 2009 Apr 2. PMID:
19539803
Article Published Date
: Aug 14, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
DNA damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo.'
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Pharm Sin B. 2022 Jan ;12(1):167-181. Epub 2021 Jul 10. PMID:
35127378
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Astilbin ameliorates cisplatin-induced nephrotoxicity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Apr ;114:227-236. Epub 2018 Feb 20. PMID:
29471006
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragaloside attenuated cisplatin-mediated renal injury.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2017 Jul-Aug;51(7-8):669-683. Epub 2017 Aug 11. PMID:
28750561
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Sep 14, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Sep 15 ;859:172490. Epub 2019 Jun 21. PMID:
31229536
Article Published Date
: Sep 14, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Astragaloside IV and saponins of rhizoma polygonati cure cyclophosphamide-induced myelosuppression in lung adenocarcinoma.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2021 ;11:630921. Epub 2021 Apr 20. PMID:
33959499
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Chemoprotective Agents
,
MicroRNA modulator
[+]
Astragaloside IV attenuates the myocardial injury caused by adriamycin by inhibiting autophagy.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:669782. Epub 2021 May 24. PMID:
34108879
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Autophagy Inhibitors
,
Cardioprotective
[+]
Astragaloside IV inhibits adriamycin-induced cardiac ferroptosis by enhancing Nrf2 signaling.
Mar 02, 2021
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2021 Mar 3. Epub 2021 Mar 3. PMID:
33656642
Article Published Date
: Mar 02, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Nrf2 activation
[+]
Astragaloside IV mediated suppression of fibroproliferation may contribute to the anti-fibrotic effect against BLM-induced pulmonary fibrosis.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2016 Oct ;39(5):1835-41. PMID:
27525425
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
[+]
Astragaloside IV protects against cisplatin-induced liver and kidney injury.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Toxicol Sci. 2019 ;44(3):167-175. PMID:
30842369
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Hepatoprotective
,
Renoprotective
[+]
Astragaloside IV-mediated a protection against cisplatin-induced acute kidney injury.
Oct 23, 2020
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2020 Oct 24 ;183:114299. Epub 2020 Oct 24. PMID:
33148504
Article Published Date
: Oct 23, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Astragalus propinquus Schischkin and Panax notoginseng (A&P) compound relieved cisplatin-induced acute kidney injury.
Jan 27, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Jan 28 ;252:112637. Epub 2020 Jan 28. PMID:
32004631
Article Published Date
: Jan 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astragalus
,
Panax Notoginseng
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Bacopa monnieri may be useful alone or in combination with other anti-emetic drugs for the treatment of chemotherapy-induced emesis in man.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Sci. 2017 Apr ;133(4):232-239. Epub 2017 Mar 12. PMID:
28363413
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Emesis
Pharmacological Actions
:
Chemoprotective Agents
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Baicalein and alpha-tocopherol inhibit toll-like receptor pathways in cisplatin-induced nephrotoxicity.
Mar 27, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2022 Mar 28 ;27(7). Epub 2022 Mar 28. PMID:
35408581
Article Published Date
: Mar 27, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
,
Vitamin E: alpha tocopherol
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
Baicalin regulates TLR4/IκBα/NFκB signaling pathway to alleviate inflammation in Doxorubicin related cardiotoxicity.
Oct 18, 2022
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2022 Oct 19 ;637:1-8. Epub 2022 Oct 19. PMID:
36375245
Article Published Date
: Oct 18, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
NF-kappaB Inhibitor
[+]
Based on activation of p62-Keap1-Nrf2 pathway, hesperidin protects arsenic-trioxide-induced cardiotoxicity.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:758670. Epub 2021 Oct 13. PMID:
34721041
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Chemotherapy-Induced Toxicity: Arsenic Trioxide
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Enhancer
Problem Substances
:
Arsenic Trioxide
[+]
Bee venom phospholipase A2 inhibits cisplatin-induced acute kidney.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Kidney Int. 2015 Sep ;88(3):550-9. Epub 2015 May 20. PMID:
25993317
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Behavioral and morphological effects of resveratrol and curcumin in rats submitted to doxorubicin-induced cognitive impairment.
Oct 31, 2021
Click here to read the entire abstract
Pubmed Data
: Res Vet Sci. 2021 Nov ;140:242-250. Epub 2021 Sep 10. PMID:
34536813
Article Published Date
: Oct 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Resveratrol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Beneficial effects of cynaroside on cisplatin-induced kidney injury.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Res. 2018 Apr ;34(2):133-141. Epub 2018 Apr 15. PMID:
29686775
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Beneficial effects of procyanidin B2 on adriamycin-induced nephrotic syndrome.
Aug 14, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Aug 15 ;13(16):8436-8464. Epub 2022 Aug 15. PMID:
35861207
Article Published Date
: Aug 14, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Procyanidin B2
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
Berberine alleviated doxorubicin induced cardiotoxicity via inhibition of the metabolism of doxorubicin and reduced accumulation of doxorubicinol selectively in hearts.
May 12, 2015
Click here to read the entire abstract
Pubmed Data
: Xenobiotica. 2015 May 13:1-6. Epub 2015 May 13. PMID:
25970816
Article Published Date
: May 12, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Berberine alleviates doxorubicin-induced myocardial injury and fibrosis.
Feb 06, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2023 Feb 7 ;24(4). Epub 2023 Feb 7. PMID:
36834687
Article Published Date
: Feb 06, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Nrf2 activation
[+]
Berberine exerts protective effects on cardiac senescence by regulating the Klotho/SIRT1 signaling pathway.
Jun 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Jul ;151:113097. Epub 2022 May 24. PMID:
35609366
Article Published Date
: Jun 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
SIRT1 Activator
[+]
Berberine exhibited protective effects against doxorubicin induced heart tissue free radical injury.
Mar 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Apr ;15(4):5721-5729. Epub 2018 Feb 9. PMID:
29552206
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Berberine protects against cisplatin-induced renal fibrosis in rats.
Nov 14, 2022
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2022 Nov 15 ;309:121040. Epub 2022 Oct 5. PMID:
36208663
Article Published Date
: Nov 14, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Fibrotic
,
Chemoprotective Agents
,
Renoprotective
[+]
Berberine regulates fecal metabolites to ameliorate 5-fluorouracil induced intestinal mucositis through modulating gut microbiota
Jan 16, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2020 Jan 17 ;124:109829. Epub 2020 Jan 17. PMID:
31958765
Article Published Date
: Jan 16, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Mucositis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberis integerrima hydro-alcoholic root extract ant its constituent berberine protect against cisplatin-induced nephro- and hepato-toxicity.
Apr 11, 2022
Click here to read the entire abstract
Pubmed Data
: Am J Med Sci. 2022 Apr 12. Epub 2022 Apr 12. PMID:
35427583
Article Published Date
: Apr 11, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Barberry
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Hepatoprotective
[+]
Beta-glucan might be useful against cisplatin toxicity in patients with cancer in terms of nervous system.
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Cir Bras. 2016 Mar ;31(3):198-205. PMID:
27050791
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Beta-glucan
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Betaine supplementation attenuates hepatic injury mediated by cisplatin.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2019 Nov ;71(6):1025-1033. Epub 2019 Jun 6. PMID:
32002889
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Betaine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Bifidobacterium bifidum G9-1 attenuates 5-fluorouracil-induced intestinal mucositis in mice.
Jun 06, 2017
Click here to read the entire abstract
Pubmed Data
: Clin Exp Pharmacol Physiol. 2017 Jun 7. Epub 2017 Jun 7. PMID:
28590519
Article Published Date
: Jun 06, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bifidobacterium Bifidum
,
Probiotics
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Chemoprotective Agents
,
Gastrointestinal Agents
,
Gastroprotective
Additional Keywords
:
Microbiota
[+]
Bilberry enhances the effects and reduces the side effects of the chemotoxic agaent 5-flouroucil.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2007;29(1):55-65. PMID:
17611294
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Bilberry
Diseases
:
Chemotherapy Induced Myelotoxicity
,
Myelotoxicity
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Drug Side Effect Attenuation
[+]
Bile acid conjugate prevents Oxaliplatin chemotherapy-induced fatty liver.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer. 2010 Jan 1;116(1):251-5. PMID:
19890960
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bile salts
Diseases
:
Chemotherapy-Induced Liver Toxicity
,
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Oxaliplatin
,
Fatty Liver
[+]
Biochemical and morphological evaluation of the effects of propolis on cisplatin induced kidney damage in rats.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2019 Apr ;94(3):204-213. Epub 2018 Dec 4. PMID:
30512970
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bee Propolis
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Bitter apple extracts could be a potential adjuvant in cisplatin-based chemotherapy.
Dec 12, 2017
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2017 Dec 13. Epub 2017 Dec 13. PMID:
29236674
Article Published Date
: Dec 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Apple
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
,
Renoprotective
[+]
Bitter apple pretreatment attenuates cyclophosphamide-induced oxidative stress and the subsequent DNA damage in mice.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ScientificWorldJournal. 2013 ;2013:980480. Epub 2013 Nov 7. PMID:
24324391
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Apple
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Blackberry juice anthocyanidins limit cisplatin-induced renal pathophysiology in mice.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Pathophysiology. 2019 Jun ;26(2):137-143. Epub 2019 Apr 19. PMID:
31040041
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blackberry
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
Boerhaavia diffusa is effective in mitigating cisplatin-induced nephrotoxicity.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Regul Toxicol Pharmacol. 2016 Nov ;81:341-352. Epub 2016 Sep 22. PMID:
27667768
Article Published Date
: Oct 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Boerhaavia diffusa
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
[+]
Bone-marrow-derived mesenchymal stem cells, their conditioned media, and olive leaf extract protect against cisplatin-induced toxicity.
Sep 05, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxics. 2022 Sep 6 ;10(9). Epub 2022 Sep 6. PMID:
36136492
Article Published Date
: Sep 05, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Olive leaf extract
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
[+]
Boswellic acids, pentacyclic triterpenes, attenuate oxidative stress, and bladder tssue damage in cyclophosphamide-induced cystitis.
Apr 25, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ACS Omega. 2022 Apr 26 ;7(16):13697-13703. Epub 2022 Apr 14. PMID:
35559194
Article Published Date
: Apr 25, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Cystitis
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
[+]
Brassica rapa (Mustard Greens) have a protective effect on cisplatin-induced nephrotoxicity in cells and rats.
Dec 01, 2006
Click here to read the entire abstract
Pubmed Data
: Biol Pharm Bull. 2006 Dec;29(12):2436-41. PMID:
17142978
Article Published Date
: Dec 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Mustard Greens
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Antineoplastic Agents
,
Plant Extracts
[+]
Bromelain protects against cisplatin-induced ocular toxicity through mitigating oxidative stress and inflammation.
Dec 12, 2021
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2021 Dec 13:1-8. Epub 2021 Dec 13. PMID:
34894956
Article Published Date
: Dec 12, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Bromelain
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
[+]
Butylphthalide could be a therapeutic potential against doxorubicin-induced neurotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:9125601. Epub 2018 Aug 16. PMID:
30186550
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Celery Oil
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Neuroprotective Agents
[+]
C-phycocyanin relieved symptoms associated with cyclophosphamide-induced cystitis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:8424872. Epub 2019 Jul 29. PMID:
31467580
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Spirulina
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Cystitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
Additional Keywords
:
C-phycocyanin
[+]
C. indicum ethanol extract could attenuate cisplatin-induced nephrotoxicity and might be a beneficial agent for acute renal failure management.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Nat Prod Commun. 2015 Mar ;10(3):397-402. PMID:
25924514
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain.
Dec 14, 2020
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2020 Dec 15 ;181:108334. Epub 2020 Oct 1. PMID:
33011199
Article Published Date
: Dec 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Chemobrain
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Caffeic acid phenethyl ester may be protective against damage caused by cisplatin in the testicles.
Jul 05, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Med Sci. 2020 Jul 6. Epub 2020 Jul 6. PMID:
32628437
Article Published Date
: Jul 05, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Malondialdehyde Down-regulation
[+]
Caffeic acid phenetyl ester, a compound found within bee propolis, protects against doxorubucin-induced cardiotoxicity in rats.
Sep 30, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Ind Med. 2010 Sep 30. Epub 2010 Sep 30. PMID:
14745846
Article Published Date
: Sep 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bee Propolis
,
Caffeic acid phenethyl ester
Diseases
:
Cardiotoxicity: Chemotherapy-Induced
,
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Drug: Doxorubicin
[+]
Calorie restriction can reduce cardiac doxorubicin accumulation, and confirms its protective role against doxorubicin-induced cardiac dysfunction.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Cancer Ther. 2019 Jan-Dec;18:1534735419843999. PMID:
30999765
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Therapeutic Actions
:
Dietary Modification: Low Calorie Diet
,
Exercise
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Camel milk ameliorates 5-fluorouracil-induced renal injury.
Apr 19, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 Apr 20 ;46(4):1628-1642. Epub 2018 Apr 20. PMID:
29694984
Article Published Date
: Apr 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Chemoprotective Agents
[+]
Camel milk had an antioxidant effect and together with cisplatin managed to decrease hepatocarcinogenesis.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):1513-1520. PMID:
28372475
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Liver Cancer
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Chemotherapeutic
[+]
Camel milk has protective effects against the clastogenic and cytotoxic effects of cisplatin.
Mar 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi J Biol Sci. 2010 Apr ;17(2):159-66. Epub 2010 Feb 20. PMID:
23961073
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
,
Chemoprotective Agents
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
[+]
Camel milk may have an immunopotentiating role in diseases or conditions associated with leukopenia or drug-induced toxicities.
Aug 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Health Sci (Qassim). 2017 Sep-Oct;11(4):18-22. PMID:
29085263
Article Published Date
: Aug 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Leukopenia
Pharmacological Actions
:
Chemoprotective Agents
[+]
Cannabidiol may represent a promising new protective strategy against cisplatin-induced nephrotoxicity.
Feb 28, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Exp Ther. 2009 Mar ;328(3):708-14. Epub 2008 Dec 12. PMID:
19074681
Article Published Date
: Feb 28, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Chemoprotective Agents
[+]
Cannabidiol represents a potential protective agent against doxorubicin cardiac injury.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2013 Sep ;36(2):347-57. Epub 2013 May 10. PMID:
23721741
Article Published Date
: Aug 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabigerol (CBG) attenuates mechanical hypersensitivity elicited by chemotherapy-induced peripheral neuropathy.
Jan 09, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pain. 2022 10 ;26(9):1950-1966. Epub 2022 Aug 4. PMID:
35899583
Article Published Date
: Jan 09, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Cannabigerol
,
Cannabinoids
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions
:
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Cannabis cannabinoids can achieve analgesic effects against cisplatin neuropathy.
May 22, 2016
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2016 May 23. Epub 2016 May 23. PMID:
27214593
Article Published Date
: May 22, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Delta-tetrahydrocannabinol (THC)
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Analgesics
[+]
Cardiac progenitor cells activated by mitochondrial delivery of resveratrol enhance the survival of a doxorubicin-induced cardiomyopathy.
Jan 09, 2018
Click here to read the entire abstract
Pubmed Data
: J Control Release. 2018 Jan 10 ;269:177-188. Epub 2017 Nov 14. PMID:
29146241
Article Published Date
: Jan 09, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Cardio-protective effects of terminalia catappa leaves and terminalia chebula fruit extract in doxorubicin-induced cardiomyopathy.
May 01, 2022
Click here to read the entire abstract
Pubmed Data
: Biomarkers. 2022 May 2:1-8. Epub 2022 May 2. PMID:
35400254
Article Published Date
: May 01, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Terminalia
Diseases
:
Cardiomyopathy
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Cardioprotective effect of maternal supplementation with resveratrol on toxicity Induced by doxorubicin in offspring cardiomyocytes.
Oct 07, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Arq Bras Cardiol. 2021 Oct 8. Epub 2021 Oct 8. PMID:
34644787
Article Published Date
: Oct 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Prenatal Chemical Exposures
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Cardioprotective effect of paeonol on chronic heart failure induced by doxorubicin.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cardiovasc Med. 2022 ;9:695004. Epub 2022 Jul 5. PMID:
35865382
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Paeonol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Heart Failure
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
,
MicroRNA modulator
[+]
Cardioprotective effect of Rheum turkestanicum against doxorubicin-induced toxicity.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:909079. Epub 2022 Jun 8. PMID:
35754479
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Rhubarb
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Malondialdehyde Down-regulation
[+]
Cardioprotective effect of silymarin nanoemulsion on 5-fluorouracil-induced cardiotoxicity.
Apr 10, 2022
Click here to read the entire abstract
Pubmed Data
: Arch Pharm (Weinheim). 2022 Apr 11:e2200060. Epub 2022 Apr 11. PMID:
35411625
Article Published Date
: Apr 10, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Silibinin
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cardioprotective effect of zingerone against oxidative stress, inflammation, and apoptosis induced by cisplatin or gamma radiation.
May 06, 2018
Click here to read the entire abstract
Pubmed Data
: Naunyn Schmiedebergs Arch Pharmacol. 2018 May 7. Epub 2018 May 7. PMID:
29736620
Article Published Date
: May 06, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
Radioprotective
[+]
Cardioprotective effects of 20(S)-ginsenoside Rh2 against doxorubicin-induced cardiotoxicity.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2012 ;2012:506214. Epub 2012 Oct 17. PMID:
23125868
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Cardioprotective effects of a phlorotannin extract against doxorubicin-induced cardiotoxicity.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2017 Oct ;20(10):944-950. Epub 2017 Aug 17. PMID:
28816580
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Seaweed: Brown
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Cardioprotective effects of alpha-mangostin on doxorubicin-induced cardiotoxicity in rats.
Dec 26, 2021
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2021 Dec 27. Epub 2021 Dec 27. PMID:
34962009
Article Published Date
: Dec 26, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Mangosteen
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Carnosic acid attenuates doxorubicin-induced cardiotoxicity.
Jul 31, 2022
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2022 Aug ;166:113205. Epub 2022 Jun 5. PMID:
35675861
Article Published Date
: Jul 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Carvacrol attenuates cyclophosphamide-induced oxidative stress in rat kidney.
Feb 02, 2017
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2017 Feb 3. Epub 2017 Feb 3. PMID:
28177660
Article Published Date
: Feb 02, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Chemoprotective Agents
,
Renoprotective
[+]
CBD exerts protective effects against Doxorubicin induced cardiotoxicity and cardiac dysfunction by attenuating oxidative and nitrative stress.
Jan 05, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med. 2015 Jan 6. Epub 2015 Jan 6. PMID:
25569804
Article Published Date
: Jan 05, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
Hepatoprotective
[+]
CBD seems to exert an anti-inflammatory and antioxidant activity favoring a faster resolution of oral mucositis.
May 12, 2020
Click here to read the entire abstract
Pubmed Data
: Oral Dis. 2020 May 13. Epub 2020 May 13. PMID:
32400905
Article Published Date
: May 12, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Oral Mucositis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
[+]
Celery has a protective effect against doxorubicin toxicity.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Molecules. 2009 ;14(4):1627-38. Epub 2009 Apr 24. PMID:
19396021
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Celery
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Drug: Doxorubicin
,
Plant Extracts
[+]
Chemoprotective role of an extract of the heart of the Phoenix dactylifera tree on adriamycin-induced cardiotoxicity and nephrotoxicity.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Chem Toxicol. 2020 Jan ;135:111045. Epub 2019 Dec 9. PMID:
31830546
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Chickpea boosted bone marrow cellularity and increased α- esterase positive cells, thus reversing myelosupproession in cisplatin-treated mice.
Mar 26, 2018
Click here to read the entire abstract
Pubmed Data
: Asian Pac J Cancer Prev. 2018 Mar 27 ;19(3):803-810. Epub 2018 Mar 27. PMID:
29582638
Article Published Date
: Mar 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chickpea
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemotherapeutic
,
Immunostimulatory
[+]
Chinese hawthorn fruit reduces inflammation and oxidative stress in rats with doxorubicin-Induced chronic heart failure.
Nov 23, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2020 Nov 24 ;26:e926654. Epub 2020 Nov 24. PMID:
33232307
Article Published Date
: Nov 23, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hawthorn
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
,
Interleukin-1 beta downregulation
[+]
Chrysanthemum indicum could enhance the anti-cancer activity of bleomycin and reduce the its induced pulmonary injury in H22 tumor-bearing mice.
Feb 23, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Feb 24 ;18(3). Epub 2017 Feb 24. PMID:
28245556
Article Published Date
: Feb 23, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Chemoprotective Agents
,
Chemosensitizer
Additional Keywords
:
Natural Substance/Drug Synergy
,
Plant Extracts
[+]
Chrysin effectively protected against doxorubicin induced cardiomyopathy.
Jul 05, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Jul 6 ;7(1):4795. Epub 2017 Jul 6. PMID:
28684738
Article Published Date
: Jul 05, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Chrysin has a protective effect against cyclophosphamide -induced hepatorenal toxicity.
Oct 15, 2019
Click here to read the entire abstract
Pubmed Data
: Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct 16. Epub 2019 Oct 16. PMID:
31620822
Article Published Date
: Oct 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Cyclophosphamide
[+]
Cinnamic acid and cinnamaldehyde revealed the promising protective effects on cisplatin induced splenotoxicity in rats
Jun 23, 2015
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2015 Jun 24. Epub 2015 Jun 24. PMID:
26108916
Article Published Date
: Jun 23, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cinnamaldehyde
,
Cinnamic acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
[+]
Cisplatin induces autophagy to enhance hepatitis B virus replication.
Dec 10, 2018
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2018 Dec 11. Epub 2018 Dec 11. PMID:
30550853
Article Published Date
: Dec 10, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Hepatitis B
Additional Keywords
:
Increased Risk
[+]
Cisplatin-induced LLC-PK1 renal cell damage was significantly reduced by tetrahydrocurcumin treatment.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2015 Mar ;81(4):286-91. Epub 2015 Feb 26. PMID:
25719941
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Tetrahydrocurcumin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Chemotherapeutic
,
Renoprotective
[+]
Cisplatin-induced testicular apoptosis can be prevented by administration of curcumin, vitamin E, and combination therapy.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Turk J Urol. 2018 Jan ;44(1):16-23. Epub 2018 Jan 8. PMID:
29484222
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Vitamin E
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Cisplatin-related ototoxicity can be prevented in rats by the administration of chrysin.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Indian J Otolaryngol Head Neck Surg. 2014 Dec ;66(4):369-74. Epub 2013 Nov 28. PMID:
26396946
Article Published Date
: Nov 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Citrus extract modulates genotoxicity induced by cyclophosphamide in mice bone marrow cells.
Mar 31, 2005
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2005 Apr ;57(4):505-9. PMID:
15831212
Article Published Date
: Mar 31, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Antimutagenic Agents
,
Antioxidants
,
Chemoprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Clitoria ternatea) synergized mesenchymal stem cells by modulating the inflammatory response in rats with cisplatin-induced acute kidney injury.
Nov 12, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceuticals (Basel). 2022 Nov 13 ;15(11). Epub 2022 Nov 13. PMID:
36422526
Article Published Date
: Nov 12, 2022
Study Type
: Animal Study
Additional Links
Substances
: