Chemotherapy-Induced Toxicity: Bleomycin

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35 Substances Researched for Chemotherapy-Induced Toxicity: Bleomycin
NameACCKFocus
Curcumin816Locked
Ginkgo biloba36Locked
Tanshinone IIA36Locked
Onion15Locked
Resveratrol24Locked
Walnut24Locked
Alpha-Lipoic Acid12Locked
Ashwagandha12Locked
Astragaloside12Locked
Carnitine12Locked
Chrysanthemum Indicum12Locked
Cordyceps Militaris12Locked
Cordyceps sinensis12Locked
EGCG (Epigallocatechin gallate)12Locked
Ellagic Acid12Locked
Fisetin12Locked
Flaxseed12Locked
Garlic12Locked
Ginsenosides12Locked
Gotu Kola12Locked
Hu Zhang (Polygonum cuspidatum)12Locked
Lecithin12Locked
Medicinal Mushrooms12Locked
Orange: Mandarin12Locked
Palmitoylethanolamide 12Locked
Passion fruit12Locked
Red Sage12Locked
Royal Jelly12Locked
Safflower12Locked
St. Johns Wort12Locked
Superoxide dismutase12Locked
Citrus naringin11Locked
Flavonoids11Locked
Honokiol11Locked
Paeoniflorin11Locked
2 Problem Substances Researched for Chemotherapy-Induced Toxicity: Bleomycin
NameACCKFocus
Dl-alpha-tocopherol acetate110Locked
Bleomycin39Locked
2 Problematic Actions Researched for Chemotherapy-Induced Toxicity: Bleomycin
NameACCKFocus
Electromagnetic Field Harms11Locked
Electromagnetic Radiation11Locked
Related Topics

Chemotherapy-Induced Toxicity: Bleomycin is a Sub of the following Topic

View the Evidence:
63 Abstracts with Chemotherapy-Induced Toxicity: Bleomycin Research

[+]

Dl-alpha-tocopherol acetate does not protect against chemotherapy-induced chromosome damage and reduces the level of plasma gamma tocopherol.Feb 01, 2002

Pubmed Data : Melanoma Res. 2002 Feb;12(1):83-90. PMID: 11828262
Article Published Date : Feb 01, 2002
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Melanoma
Problem Substances : Dl-alpha-tocopherol acetate
[+]

Onion extract may have protective effects against BLM-induced cyto- and genotoxicity in human lymphocytes.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2016 ;13(2). Epub 2016 Feb 19. PMID: 26907305
Article Published Date : Dec 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Onion
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Bleomycin
[+]

Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis.Apr 30, 2022

Pubmed Data : Drug Chem Toxicol. 2022 May ;45(3):1264-1275. Epub 2020 Sep 14. PMID: 32924642
Article Published Date : Apr 30, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Diosgenin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Transforming growth factor beta (TGF-β) inhibitor
[+]

Thymoquinone ameliorates bleomycin-induced reproductive toxicity in male Balb/c mice.Nov 23, 2021

Pubmed Data : Hum Exp Toxicol. 2021 Nov 24:9603271211048184. Epub 2021 Nov 24. PMID: 34818114
Article Published Date : Nov 23, 2021
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents
[+]

A Chinese herbal formula containing Red Sage, Cordyceps and Peach kernel is superior to methylprednisone against experimental pulmonary fibrosis. May 01, 2007

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2007 May;32(9):835-9. PMID: 17639988
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : Red Sage
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Alpha lipoic acid attenuates bleomycin-induced pulmonary fibrosis in mice. Jun 01, 2007

Pubmed Data : Int J Mol Med. 2007 Jun;19(6):865-73. PMID: 17487418
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
[+]

Amelioration of bleomycin and methotrexate-induced pulmonary toxicity by serratiopeptidase and fisetin.Dec 22, 2020

Pubmed Data : Nutr Cancer. 2020 Dec 23:1-10. Epub 2020 Dec 23. PMID: 33353415
Article Published Date : Dec 22, 2020
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Drug-Induced Toxicity: Methotrexate
Pharmacological Actions : Chemoprotective Agents
[+]

Amelioration of bleomycin induced pulmonary fibrosis by administration of Salvianolic acid B.Nov 17, 2022

Pubmed Data : Vet Ital. 2022 Nov 18 ;58(1):87-101. Epub 2022 Nov 18. PMID: 36398675
Article Published Date : Nov 17, 2022
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Ameliorative effects of arctigenin on pulmonary fibrosis induced by bleomycin via the antioxidant activity.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:3541731. Epub 2022 Jul 5. PMID: 35847593
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Chemoprotective Agents
[+]

An extract of Mandarin Orange demonstrates anti-pulmonary fibrosis effects. Oct 29, 2009

Pubmed Data : J Ethnopharmacol. 2009 Oct 29;126(1):143-8. Epub 2009 Jul 28. PMID: 19643175
Article Published Date : Oct 29, 2009
Study Type : Animal Study
Additional Links
Substances : Orange: Mandarin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
[+]

Antifibrotic mechanism of piceatannol in bleomycin-induced pulmonary fibrosis in mice.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:771031. Epub 2022 Jun 7. PMID: 35747752
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Piceatannol
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Asiatic acid might be an effective candidate for pulmonary fibrosis and inflammation treatment.Apr 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 May ;89:1297-1309. Epub 2017 Mar 17. PMID: 28320097
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Inflammation
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
[+]

Astragaloside IV mediated suppression of fibroproliferation may contribute to the anti-fibrotic effect against BLM-induced pulmonary fibrosis.Sep 30, 2016

Pubmed Data : Inflammation. 2016 Oct ;39(5):1835-41. PMID: 27525425
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents
[+]

Chrysanthemum indicum could enhance the anti-cancer activity of bleomycin and reduce the its induced pulmonary injury in H22 tumor-bearing mice.Feb 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Feb 24 ;18(3). Epub 2017 Feb 24. PMID: 28245556
Article Published Date : Feb 23, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents, Chemosensitizer
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
[+]

Cordyceps alleviates bleomycin-induced alveolitis and fibrosis. Dec 01, 2007

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(24):2623-7. PMID: 18338602
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Cordyceps sinensis
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
[+]

Cordyceps militaris treatment significantly alleviated the severity of bleomycin-induced acute lung injury in mice.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2015 ;36(5):2003-11. Epub 2015 Jul 17. PMID: 26202360
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents
[+]

Curcumin can alleviate alveolitis and pulmonary fibrosis induced by bleomycin in rats.Mar 01, 2007

Pubmed Data : Zhonghua Jie He He Hu Xi Za Zhi. 2007 Mar;30(3):197-201. PMID: 17572999
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Alveolitis: Fibrosing, Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
[+]

Curcumin has a similar effect to hydrocortisone in preventing bleomycin-induced pulmonary fibrosis. Jun 13, 2007

Pubmed Data : J Ethnopharmacol. 2007 Jun 13;112(2):292-9. Epub 2007 Mar 13. PMID: 17434272
Article Published Date : Jun 13, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Curcumin inhibits bleomycin-induced pulmonary fibrosis in rats.Sep 01, 2000

Pubmed Data : Br J Pharmacol. 2000 Sep;131(2):169-72. PMID: 10991907
Article Published Date : Sep 01, 2000
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Pharmacological Actions : Anti-Bacterial Agents
[+]

Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury.Jan 08, 2010

Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 2010 Jan 8. Epub 2010 Jan 8. PMID: 20061443
Article Published Date : Jan 08, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Drug Side Effect Attenuation
[+]

Curcumin is more effective than prednisone at suppressing bleomycin-induced pulmonary fibrosis in rats. May 01, 2008

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008 May;26(5):257-61. PMID: 18727865
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Curcumin may play its therapetuic role by leveling down the content of extracellular matrix in rats with pulmonary fibrosis induced by bleomycin.Apr 01, 2006

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2006 Apr;31(7):570-3. PMID: 16780161
Article Published Date : Apr 01, 2006
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
[+]

Curcumin protects against bleomycin-induced damages in pulmonary functions in ratsJun 01, 2008

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2008 Jun;33(12):1434-8. PMID: 18837350
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
[+]

Curcumin protects bleomycin-induced lung injury in rats.Sep 01, 2008

Pubmed Data : Pharm Res. 2008 Sep;25(9):2181-9. Epub 2008 Apr 25. PMID: 9250724
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Lung Injury: Acute, Oxidative Stress
[+]

Dietary flaxseed oil protects against bleomycin-induced pulmonary fibrosis in rats.Dec 31, 2011

Pubmed Data : Pulm Med. 2012 ;2012:457031. Epub 2012 Aug 8. PMID: 22919480
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Problem Substances : Bleomycin
[+]

EGCG exhibits anti-fibrotic effects in a rat model of pulmonary fibrosis. Jul 15, 2009

Pubmed Data : Chem Biol Interact. 2009 Jul 15;180(2):271-80. Epub 2009 Mar 20. PMID: 19497426
Article Published Date : Jul 15, 2009
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
[+]

Ellagic acid attenuates bleomycin and cyclophosphamide-induced pulmonary toxicity.Jul 31, 2013

Pubmed Data : Food Chem Toxicol. 2013 Aug ;58:210-9. Epub 2013 Apr 17. PMID: 23603381
Article Published Date : Jul 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents
[+]

Ganoderic acid A inhibits bleomycin-induced lung fibrosis.Dec 31, 2019

Pubmed Data : Pharmacology. 2020 ;105(9-10):568-575. Epub 2020 Jan 15. PMID: 31940650
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Gingko biloba prevents bleomycin-induced oxidative injury in rats. Feb 01, 2006

Pubmed Data : Toxicol Ind Health. 2006 Feb;22(1):47-52. PMID: 16572711
Article Published Date : Feb 01, 2006
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Antioxidants
Additional Keywords : Antineoplastic Agents, Plant Extracts
[+]

Ginkgo biloba has a positive effect on pulmonary interstitial fibrosis in ratsJun 01, 2000

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Jun;20(6):441-3. PMID: 11789230
Article Published Date : Jun 01, 2000
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Pharmacological Actions : NF-kappaB Inhibitor, Transforming growth factor beta (TGF-β) inhibitor
[+]

Ginsenoside Rb1 alleviates bleomycin-induced pulmonary inflammation and fibrosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2022 ;16:1793-1809. Epub 2022 Jun 13. PMID: 35719213
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Ginsenoside Rg1 exhibits protective effect against bleomycin-induced pulmonary fibrosis in rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2016 ;39(8):1284-92. PMID: 27476938
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents
[+]

Hu Zhang (Polygonum cuspidatum), a rich source of resveratrol, inhibits the expression of inflammation in lung fibroblasts and reduces alveolitis and pulmonary fibrosis. Jun 01, 2009

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2009 Jun;34(12):1574-7. PMID: 19777850
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Hu Zhang (Polygonum cuspidatum), Resveratrol
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Hydroxysafflor yellow A attenuates bleomycin-induced pulmonary fibrosis.Mar 31, 2016

Pubmed Data : Phytother Res. 2016 Apr ;30(4):577-87. Epub 2016 Jan 18. PMID: 26777519
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Hyperforin, a compound found within St. John's wort, has powerful anti-inflammatory therapeutic potential in reducing lung fibrosis. May 01, 2007

Pubmed Data : J Pharmacol Exp Ther. 2007 May;321(2):492-500. Epub 2007 Feb 8. PMID: 17289834
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : St. Johns Wort
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Cystic Fibrosis, Pulmonary Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Juglanin alleviates bleomycin-induced lung injury.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Jul ;127:110119. Epub 2020 Apr 7. PMID: 32276127
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

L-carnitine and ginkgo biloba extract exhibits a protective agent in an animal model of bleomycin-induced lung fibrosis Jun 01, 2002

Pubmed Data : Pharmacol Res. 2002 Jun;45(6):461-7. PMID: 12162946
Article Published Date : Jun 01, 2002
Study Type : Animal Study
Additional Links
Substances : Carnitine, Ginkgo biloba
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Lecithinized superoxide dismutase has protective activity against bleomycin-induced pulmonary fibrosis. Dec 24, 2009

Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 2009 Dec 24. Epub 2009 Dec 24. PMID: 20034962
Article Published Date : Dec 24, 2009
Study Type : Animal Study
Additional Links
Substances : Lecithin, Superoxide dismutase
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Additional Keywords : Drug Side Effect Attenuation
[+]

Palmitoylethanolamide reduces the extent of lung inflammation in a mouse model of idiopathic pulmonary fibrosis.Aug 31, 2016

Pubmed Data : Pharmacol Res. 2016 Sep ;111:405-412. Epub 2016 Jul 8. PMID: 27402190
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
[+]

Passion fruit peel extract attenuates bleomycin-induced pulmonary fibrosis.Jul 31, 2014

Pubmed Data : Can J Physiol Pharmacol. 2014 Aug ;92(8):631-9. Epub 2014 Apr 29. PMID: 24933624
Article Published Date : Jul 31, 2014
Study Type : Animal Study
Additional Links
Substances : Passion fruit
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Pinocembrin ameliorates skin fibrosis via inhibiting TGF-β1 signaling pathway. Jan 18, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2021 08 19 ;11(8). Epub 2021 Aug 19. PMID: 34439906
Article Published Date : Jan 18, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Fibrosis, Keloid
Pharmacological Actions : Anti-Fibrotic, Transforming growth factor beta (TGF-β) inhibitor
[+]

Pinocembrin relieves lipopolysaccharide and bleomycin induced lung inflammation.Dec 31, 2020

Pubmed Data : Int Immunopharmacol. 2021 Jan ;90:107230. Epub 2020 Dec 9. PMID: 33290968
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Protective effect of a polyphenols-rich extract from Inonotus Sanghuang on bleomycin-induced acute lung injury.Jul 31, 2019

Pubmed Data : Life Sci. 2019 Aug 1 ;230:208-217. Epub 2019 May 29. PMID: 31152815
Article Published Date : Jul 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Medicinal Mushrooms
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Antioxidants, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Protective effects of alpha-lipoic acid on bleomycin-induced skin fibrosis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hum Exp Toxicol. 2022 Jan-Dec;41:9603271211065975. PMID: 35187969
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Transforming growth factor beta (TGF-β) inhibitor
[+]

Resveratrol alleviates chemotherapy-induced (bleomycin) lung injury in rats. Jan 01, 2007

Pubmed Data : : Pulm Pharmacol Ther. 2007;20(6):642-9. Epub 2006 Sep 3. PMID: 17035056
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Adriamycin, Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Royal jelly attenuates oxidative damage and fibrosis induced by bleomycin.Jul 20, 2016

Pubmed Data : Can J Physiol Pharmacol. 2016 Jul 21:1-9. Epub 2016 Jul 21. PMID: 27841941
Article Published Date : Jul 20, 2016
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Bleomycin
[+]

S-allyl-l-cysteine attenuates bleomycin-induced pulmonary fibrosis and inflammation.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2019 Apr ;139(4):377-384. Epub 2019 Mar 14. PMID: 30928090
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tanshinone IIA ameliorates bleomycin-induced pulmonary fibrosis.Jun 30, 2015

Pubmed Data : J Surg Res. 2015 Jul ;197(1):167-75. Epub 2015 Mar 13. PMID: 25911951
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2015 Jun ;11(6):4190-6. Epub 2015 Feb 11. PMID: 25672255
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2014 ;11(6):578-86. Epub 2014 Apr 7. PMID: 24782646
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Inflammation, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

The efficacy and safety of pinocembrin in a model of bleomycin-induced pulmonary fibrosis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2021 ;16(12):e0260719. Epub 2021 Dec 2. PMID: 34855848
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemosensitizer
[+]

Walnut extract decreases bleomycin induced oxidative stress and lung inflammation.Jul 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Aug 1 ;94:418-429. Epub 2017 Aug 1. PMID: 28778045
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents
[+]

Withaferin A attenuates bleomycin-induced scleroderma.Oct 31, 2018

Pubmed Data : Biofactors. 2018 Nov ;44(6):507-517. Epub 2018 Oct 27. PMID: 30367690
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Scleroderma
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Chemoprotective Agents
[+]

Andrographolide ameliorates bleomycin-induced pulmonary fibrosis.Mar 14, 2020

Pubmed Data : Toxicol Lett. 2020 Mar 15 ;321:103-113. Epub 2019 Nov 6. PMID: 31706003
Article Published Date : Mar 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Transforming growth factor beta (TGF-β) inhibitor
[+]

Astilbin ameliorates pulmonary fibrosis via blockade of Hedgehog signaling pathway.Dec 31, 2017

Pubmed Data : Pulm Pharmacol Ther. 2018 06 ;50:19-27. Epub 2018 Apr 3. PMID: 29621624
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Astragaloside IV inhibits bleomycin-induced ferroptosis in human umbilical vein endothelial cells by mediating LPC.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:6241242. Epub 2021 Nov 1. PMID: 34760046
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Chemoprotective Agents
[+]

Component analysis and anti-pulmonary fibrosis effects of Rosa sterilis juice.Dec 12, 2022

Pubmed Data : Food Funct. 2022 Dec 13 ;13(24):12915-12924. Epub 2022 Dec 13. PMID: 36444933
Article Published Date : Dec 12, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Polyphenols, Rose
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents
[+]

Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells.Jun 13, 2022

Pubmed Data : Drug Chem Toxicol. 2022 Jun 14:1-10. Epub 2022 Jun 14. PMID: 35702048
Article Published Date : Jun 13, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Chemotherapy-Induced Toxicity: Oxaliplatin
Pharmacological Actions : Chemoprotective Agents, Genoprotective
[+]

Naringin dose dependently decreased the total chromosome aberrations frequency induced by bleomycin.May 04, 2015

Pubmed Data : Drug Chem Toxicol. 2015 May 5:1-5. Epub 2015 May 5. PMID: 25941869
Article Published Date : May 04, 2015
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, DNA damage
Pharmacological Actions : Genoprotective
Additional Keywords : Dose Response
[+]

Paeoniflorin suppresses TGF-β mediated epithelial-mesenchymal transition in pulmonary fibrosisMay 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Pharmacol Sin. 2016 Jun ;37(6):794-804. Epub 2016 May 2. PMID: 27133302
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions : Anti-Fibrotic
[+]

Piceatannol could protect against oxidative injury and collagen synthesis during pulmonary fibrosis.Sep 30, 2022

Pubmed Data : Int Immunopharmacol. 2022 Oct ;111:109107. Epub 2022 Aug 3. PMID: 35932616
Article Published Date : Sep 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Piceatannol
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis
Pharmacological Actions : Anti-Fibrotic, Antioxidants
[+]

The combination of bleomycin and honokiol suggests that they can be used as combination therapy for treatment of cancer.Feb 19, 2017

Pubmed Data : Chem Res Toxicol. 2017 Feb 20 ;30(2):715-725. Epub 2017 Jan 19. PMID: 28067485
Article Published Date : Feb 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Bleomycin, Lung Cancer, Pancreatic Cancer, Skin Cancer
Pharmacological Actions : Chemoprotective Agents, Chemosensitizer
Additional Keywords : Natural Substance/Drug Synergy
[+]

These studies investigate micronuclei formation at different specific absorption rates, in conjunction with bleomycin, for 18 hours.Nov 10, 2003

Pubmed Data : Mutat Res. 2003 Nov 10 ;541(1-2):81-9. PMID: 14568297
Article Published Date : Nov 10, 2003
Study Type : In Vitro Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, DNA damage
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Adverse Pharmacological Actions : Cytotoxic, Genotoxic

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