Chemotherapy-Induced Toxicity: Paclitaxel

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41 Substances Researched for Chemotherapy-Induced Toxicity: Paclitaxel
NameACCKFocus
Acetyl-l-carnitine220Locked
Alpha-Lipoic Acid220Locked
Silibinin212Locked
Palmitoylethanolamide 37Locked
Hesperidin36Locked
Cannabinoids 35Locked
Berberine24Locked
Citrus naringin24Locked
Naringenin 24Locked
Parthenolide24Locked
Puerarin24Locked
Royal Jelly24Locked
Thymoquinone24Locked
Glycyrrhizin13Locked
Artesunate12Locked
Bee Propolis12Locked
Bee Venom12Locked
Bergamot12Locked
Beta-Caryophyllene12Locked
Beta-glucan12Locked
Caffeic acid phenethyl ester12Locked
Cannabidiol12Locked
Cannabigerol 12Locked
Cannabis12Locked
Carvacrol12Locked
Chrysin12Locked
Cucurbitacin D12Locked
Curcumin12Locked
Delta-tetrahydrocannabinol (THC)12Locked
Guduchi 12Locked
Maitake Mushroom12Locked
Paeoniflorin12Locked
Quercetin12Locked
Resveratrol12Locked
Rutin12Locked
Salvia divinorum12Locked
Vitamin E12Locked
Betulinic acid11Locked
Nicotinamide11Locked
Riboflavin (Vitamin B-2)11Locked
Thiamine (B-1) 11Locked
2 Problem Substances Researched for Chemotherapy-Induced Toxicity: Paclitaxel
NameACCKFocus
Paclitaxel314Locked
Cisplatin12Locked
3 Therapeutic Actions Researched for Chemotherapy-Induced Toxicity: Paclitaxel
NameACCKFocus
Cryotherapy220Locked
Electroacupuncture24Locked
Acupuncture12Locked
1 Problematic Actions Researched for Chemotherapy-Induced Toxicity: Paclitaxel
NameACCKFocus
Chemotherapy12Locked

View the Evidence:
55 Abstracts with Chemotherapy-Induced Toxicity: Paclitaxel Research

[+]

Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy.Apr 24, 2006

Pubmed Data : Neurosci Lett. 2006 Apr 24;397(3):219-23. Epub 2006 Jan 6. PMID: 16406309
Article Published Date : Apr 24, 2006
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Neuropathic Pain
[+]

Alpha lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy.Dec 01, 2008

Pubmed Data : Exp Neurol. 2008 Dec;214(2):276-84. Epub 2008 Sep 9. PMID: 18809400
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Neuroprotective Agents
[+]

Cryotherapy for the prevention of weekly paclitaxel-induced peripheral adverse events in breast cancer patients.Feb 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Support Care Cancer. 2020 Feb 8. Epub 2020 Feb 8. PMID: 32036471
Article Published Date : Feb 07, 2020
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Chemoprotective Agents
[+]

Cryotherapy helps to prevent paclitaxel induced peripheral neuropathy.Nov 30, 2019

Pubmed Data : Breast. 2019 Dec ;48:89-97. Epub 2019 Sep 19. PMID: 31590108
Article Published Date : Nov 30, 2019
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
Additional Keywords : Risk Reduction
Problem Substances : Paclitaxel
[+]

Mild cryotherapy for prevention of paclitaxel-induced nail toxicity in breast cancer patients.May 31, 2023

Pubmed Data : Clin Breast Cancer. 2023 Jun ;23(4):447-453. Epub 2023 Mar 8. PMID: 36997403
Article Published Date : May 31, 2023
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents
[+]

Oral silymarin formulation efficacy in management of AC-T protocol induced hepatotoxicity in breast cancer patients.Apr 15, 2021

Pubmed Data : J Oncol Pharm Pract. 2021 Apr 16:10781552211006182. Epub 2021 Apr 16. PMID: 33861657
Article Published Date : Apr 15, 2021
Study Type : Human Study
Additional Links
Substances : Silibinin
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Chemotherapy-Induced Toxicity: Doxorubicin, Chemotherapy-Induced Toxicity: Paclitaxel, Liver Damage: Drug-Induced
Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic, Hepatoprotective
[+]

Prophylactic acetyl-L-carnitine treatment against paclitaxel-evoked pain may be related to a protective effect on C-fiber mitochondria.Mar 01, 2008

Pubmed Data : Exp Neurol. 2008 Mar;210(1):229-37. Epub 2007 Nov 17. PMID: 18078936
Article Published Date : Mar 01, 2008
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Neuropathic Pain
Additional Keywords : Drug: Paclitaxel
[+]

Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Support Care Cancer. 2022 Sep ;30(9):7281-7292. Epub 2022 May 21. PMID: 35596774
Article Published Date : Aug 31, 2022
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Doxorubicin, Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Cardioprotective, Chemoprotective Agents, Neuroprotective Agents
[+]

Glycyrrhizic acid prevents paclitaxel-induced neuropathy.Apr 24, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2023 Apr 25 ;12(9). Epub 2023 Apr 25. PMID: 37174648
Article Published Date : Apr 24, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Glycyrrhizin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Palmitoylethanolamide mitigates paclitaxel toxicity in primary dorsal root ganglion neurons.Dec 13, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2022 Dec 14 ;12(12). Epub 2022 Dec 14. PMID: 36551301
Article Published Date : Dec 13, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Artesunate alleviates paclitaxel-induced neuropathic pain.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Mol Neurosci. 2022 ;15:902572. Epub 2022 May 27. PMID: 35694442
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Artesunate
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Berberine alleviates paclitaxel-induced neuropathy.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2019 Jun ;22(2):90-94. Epub 2019 Jun 30. PMID: 31338248
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents
[+]

Caffeic acid phenethyl ester attenuates paclitaxel-induced peripheral neuropathyAug 28, 2022

Pubmed Data : Curr Neurovasc Res. 2022 Aug 29. Epub 2022 Aug 29. PMID: 36043777
Article Published Date : Aug 28, 2022
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

CBD may be potent and effective at preventing the development of chemotherapy-induced peripheral neuropathy.May 25, 2017

Pubmed Data : Br J Pharmacol. 2017 May 26. Epub 2017 May 26. PMID: 28548225
Article Published Date : May 25, 2017
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)
Diseases : Chemotherapy and Radiation Toxicity, Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Vincristine, Neuropathic Pain
Pharmacological Actions : Chemoprotective Agents
[+]

Chrysin attenuates paclitaxel-induced hepatorenal toxicity in rats by suppressing oxidative damage, inflammation, and apoptosis.Oct 31, 2023

Pubmed Data : Life Sci. 2023 Nov 1 ;332:122096. Epub 2023 Sep 15. PMID: 37716503
Article Published Date : Oct 31, 2023
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Bcl-2 protein down-regulation, Chemoprotective Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

Effect of vitamin E on doxorubicin and paclitaxel-induced memory impairments.Nov 05, 2023

Pubmed Data : Cancer Chemother Pharmacol. 2023 Nov 6. Epub 2023 Nov 6. PMID: 37926754
Article Published Date : Nov 05, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Neuroprotective Agents
[+]

Electroacupuncture alleviates paclitaxel-induced peripheral neuropathic pain.Nov 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Nov 25 ;20(23). Epub 2019 Nov 25. PMID: 31775332
Article Published Date : Nov 24, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Analgesics, Chemoprotective Agents
[+]

Electroacupuncture treatment attenuates paclitaxel-induced neuropathic pain.Dec 31, 2019

Pubmed Data : J Pain Res. 2020 ;13:239-250. Epub 2020 Jan 29. PMID: 32099448
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents
[+]

Endothelial cell changes occurring upon chemotherapy exposure in mice can create an environment favorable for metastasis formation through expression of VEGFR-1.Nov 14, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Res. 2011 Nov 15 ;71(22):6976-85. Epub 2011 Oct 5. PMID: 21975929
Article Published Date : Nov 14, 2011
Study Type : Animal Study
Additional Links
Diseases : Cancer Metastasis, Chemotherapy-Induced Toxicity: Cisplatin, Chemotherapy-Induced Toxicity: Paclitaxel
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Chemotherapy
Problem Substances : Cisplatin, Paclitaxel
[+]

Formulated curcumin prevents paclitaxel-induced peripheral neuropathy.Jun 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Jun 17 ;14(6). Epub 2022 Jun 17. PMID: 35745868
Article Published Date : Jun 16, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Neuroprotective Agents
[+]

Hesperidin has a protective effect on paclitaxel-induced testicular toxicity.May 31, 2023

Pubmed Data : Reprod Toxicol. 2023 Jun ;118:108369. Epub 2023 Mar 24. PMID: 36966900
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Inflammation, Oxidative Stress, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity.Feb 06, 2010

Pubmed Data : Cancer Immunol Immunother. 2010 Feb 6. Epub 2010 Feb 6. PMID: 20140432
Article Published Date : Feb 06, 2010
Study Type : Animal Study
Additional Links
Substances : Beta-glucan, Maitake Mushroom
Diseases : Chemotherapy Induced Myelotoxicity , Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Paclitaxel, Myelotoxicity
Pharmacological Actions : Chemopreventive
Additional Keywords : Drug Side Effect Attenuation
[+]

Naringenin relieves paclitaxel-induced pain by suppressing calcitonin gene-related peptide signalling.May 06, 2024

Pubmed Data : Br J Pharmacol. 2024 May 7. Epub 2024 May 7. PMID: 38715438
Article Published Date : May 06, 2024
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Antinoceceptive , Apoptotic, Chemoprotective Agents
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Naringin protects against paclitaxel-induced toxicity in rat testicular tissues.Jun 30, 2024

Pubmed Data : J Biochem Mol Toxicol. 2024 Jul ;38(7):e23751. PMID: 38879801
Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Chemoprotective Agents
[+]

Paclitaxel-associated mechanical sensitivity and neuroinflammation are sex-, time-, and site-specific and prevented through cannabigerol administration.Apr 11, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2024 Apr 12 ;25(8). Epub 2024 Apr 12. PMID: 38673862
Article Published Date : Apr 11, 2024
Study Type : Animal Study
Additional Links
Substances : Cannabigerol , Cannabinoids
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Hyperalgesia, Inflammation
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Palmitoylethanolamide possesses potential to treat peripheral neuropathy in cancer patients undergoing chemotherapy.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Exp Ther. 2016 Nov ;359(2):310-318. Epub 2016 Sep 8. PMID: 27608657
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Hyperalgesia
Pharmacological Actions : Chemoprotective Agents
[+]

Parthenolide as a potential analgesic in the treatment of paclitaxel-induced neuropathic pain.Nov 30, 2023

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Dec ;396(12):3707-3721. Epub 2023 Jun 12. PMID: 37306715
Article Published Date : Nov 30, 2023
Study Type : Animal Study
Additional Links
Substances : Parthenolide
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Analgesics
[+]

Prophylactic topical paeoniflorin prevents mechanical allodynia caused by paclitaxel.Feb 14, 2017

Pubmed Data : Phytomedicine. 2017 Feb 15 ;25:1-7. Epub 2016 Dec 19. PMID: 28190463
Article Published Date : Feb 14, 2017
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Hyperalgesia
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Protective effect of carvacrol against paclitaxel-induced ototoxicity. Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk Arch Otorhinolaryngol. 2020 Dec ;58(4):241-248. Epub 2020 Dec 1. PMID: 33554199
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Puerarin relieves paclitaxel-induced neuropathic pain.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1510. Epub 2019 Jan 7. PMID: 30666203
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Analgesics, Chemoprotective Agents
[+]

Quercetin has therapeutic potential in treating paclitaxel-induced peripheral neuropathy.Aug 07, 2016

Pubmed Data : Acta Pharmacol Sin. 2016 Aug 8. Epub 2016 Aug 8. PMID: 27498772
Article Published Date : Aug 07, 2016
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Chemoprotective Agents
[+]

Resveratrol improves paclitaxel-induced cognitive impairment.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2023 ;17:1125-1138. Epub 2023 Apr 12. PMID: 37077409
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Neuroprotective Agents, SIRT1 Activator
[+]

Role of parthenolide in paclitaxel-induced oxidative stress injury and impaired reproductive function in rat testicular tissue.Nov 07, 2023

Pubmed Data : Chem Biol Interact. 2023 Nov 8 ;387:110793. Epub 2023 Nov 8. PMID: 37949423
Article Published Date : Nov 07, 2023
Study Type : Animal Study
Additional Links
Substances : Parthenolide
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants, Chemoprotective Agents
[+]

Royal jelly could protect against the hepatotoxicity of paclitaxel.Aug 04, 2016

Pubmed Data : Hum Exp Toxicol. 2016 Aug 5. Epub 2016 Aug 5. PMID: 27496854
Article Published Date : Aug 04, 2016
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents, Hepatoprotective
Additional Keywords : Dose Response
[+]

Rutin and hesperidin alleviate paclitaxel-induced nephrocardiotoxicity.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2023 ;2023:5068304. Epub 2023 Feb 22. PMID: 36874615
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Hesperidin, Rutin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Antioxidants, Cardioprotective, Renoprotective
[+]

Salvinorin A supressed both mechanical and cold allodynia in the paclitaxel-induced neuropathic pain model, in a dose-dependent manner.Feb 02, 2017

Pubmed Data : Eur J Pain. 2017 Feb 3. Epub 2017 Feb 3. PMID: 28158929
Article Published Date : Feb 02, 2017
Study Type : Animal Study
Additional Links
Substances : Salvia divinorum
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Dose Response
[+]

Silymarin protects the liver from the toxicity of the anticancer drug paclitaxel.Jul 31, 2023

Pubmed Data : Tissue Cell. 2023 Aug ;83:102158. Epub 2023 Jul 7. PMID: 37459721
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Liver Damage: Drug-Induced, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Chemoprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The involvement of the noradrenergic system in the antinociceptive effect of cucurbitacin D on mice with paclitaxel-induced neuropathic pain.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:1055264. Epub 2023 Jan 4. PMID: 36686685
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Cucurbitacin D
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Antinoceceptive , Chemoprotective Agents, Neuroprotective Agents
[+]

The potential antinociceptive effect and mechanism of Cannabis sativa extract on paclitaxel-induced neuropathic pain.Apr 24, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2024 Apr 25 ;29(9). Epub 2024 Apr 25. PMID: 38731449
Article Published Date : Apr 24, 2024
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Cannabis
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Analgesics, Antinoceceptive
Additional Keywords : Plant Extracts
[+]

The preventive effects of naringin and naringenin against paclitaxel-induced nephrotoxicity and cardiotoxicity.Dec 31, 2021

Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:8739815. Epub 2022 Sep 30. PMID: 36212979
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Citrus naringin, Naringenin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Cardioprotective, Chemoprotective Agents, Renoprotective
[+]

The protective effect of bergamot polyphenolic fraction on chemotherapy-induced neuropathic pain.Sep 24, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Sep 25 ;14(10). Epub 2021 Sep 25. PMID: 34681199
Article Published Date : Sep 24, 2021
Study Type : Animal Study
Additional Links
Substances : Bergamot
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Analgesics, Chemoprotective Agents
[+]

The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats.Oct 31, 2021

Pubmed Data : Life Sci. 2021 Nov 1 ;287:120104. Epub 2021 Nov 1. PMID: 34743946
Article Published Date : Oct 31, 2021
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Apoptotic, Chemoprotective Agents
[+]

The role of propolis against paclitaxel-induced oligospermia, sperm abnormality, oxidative stress and DNA damage in testes of male rats.Nov 24, 2019

Pubmed Data : Andrologia. 2019 Nov 25:e13394. Epub 2019 Nov 25. PMID: 31762066
Article Published Date : Nov 24, 2019
Study Type : Animal Study
Additional Links
Substances : Bee Propolis
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Chemoprotective Agents
Problem Substances : Paclitaxel
[+]

These findings revealed the therapeutic potential of puerarin in treating and preventing chemotherapy-induced peripheral neuropathic pain.Jan 05, 2019

Pubmed Data : Neuroreport. 2019 03 6 ;30(4):288-294. PMID: 30676543
Article Published Date : Jan 05, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Pharmacological Actions : Chemoprotective Agents
[+]

These findings suggest that ultramicronized-palmitoylethanolamide is a promising adjunct in CIPN and associated mood disorders.Aug 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2022 Aug 20 ;12(8). Epub 2022 Aug 20. PMID: 36009049
Article Published Date : Aug 19, 2022
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Chemoprotective Agents, Neuroprotective Agents
[+]

These results showed the neuropathy preventing role of berberine in paclitaxel induced neuropathy pain model in rats.Dec 09, 2018

Pubmed Data : J Pharm Pharmacol. 2018 Dec 10. Epub 2018 Dec 10. PMID: 30536411
Article Published Date : Dec 09, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Nrf2 activation
[+]

These results showed the protective effect of royal jelly on Paclitaxel induced cardiotoxicity.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2016 Feb ;19(2):221-7. PMID: 27081469
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Antioxidants, Cardioprotective, Chemoprotective Agents
[+]

These results suggest that bee venom acupuncture has potent suppressive effects against paclitaxel-induced neuropathic pain.Oct 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2017 Oct 31 ;9(11). Epub 2017 Oct 31. PMID: 29088102
Article Published Date : Oct 30, 2017
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Neuropathic Pain
Therapeutic Actions : Acupuncture
Pharmacological Actions : Chemoprotective Agents
[+]

Thymoquinone alleviates paclitaxel-induced peripheral neuropathy.Oct 17, 2023

Pubmed Data : ACS Chem Neurosci. 2023 Oct 18 ;14(20):3804-3817. Epub 2023 Oct 9. PMID: 37813830
Article Published Date : Oct 17, 2023
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymoquinone can alleviate the side effects of paclitaxel on the male reproductive system.Jul 25, 2021

Pubmed Data : Andrologia. 2021 Jul 26:e14192. Epub 2021 Jul 26. PMID: 34309886
Article Published Date : Jul 25, 2021
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Antioxidants, Chemoprotective Agents
[+]

Tinospora cordifolia ameliorates paclitaxel-induced neuropathic pain.Feb 29, 2024

Pubmed Data : J Ethnopharmacol. 2024 Mar 1 ;321:117559. Epub 2023 Dec 10. PMID: 38072294
Article Published Date : Feb 29, 2024
Study Type : Animal Study
Additional Links
Substances : Guduchi
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Analgesics, Chemoprotective Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

β-caryophyllene has antiallodynic effects on paclitaxel-induced peripheral neuropathy in mice.Sep 30, 2017

Pubmed Data : Neuropharmacology. 2017 Oct ;125:207-219. Epub 2017 Jul 18. PMID: 28729222
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents
[+]

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathyDec 31, 2018

Pubmed Data : Pain. 2019 Jan ;160(1):117-135. PMID: 30169422
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, HIV Infections
Pharmacological Actions : Neuroprotective Agents
[+]

CBD loaded microparticles as a potential formulation to improve paclitaxel and doxorubicin-based chemotherapy in breast cancer.Jan 24, 2020

Pubmed Data : Int J Pharm. 2020 Jan 25 ;574:118916. Epub 2019 Dec 4. PMID: 31811927
Article Published Date : Jan 24, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Doxorubicin, Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Antiproliferative , Chemosensitizer, Chemotherapeutic
[+]

Thiamine, riboflavin, and nicotinamide inhibit paclitaxel-induced allodynia.Aug 05, 2019

Pubmed Data : Inflammopharmacology. 2019 Aug 6. Epub 2019 Aug 6. PMID: 31388880
Article Published Date : Aug 05, 2019
Study Type : In Vitro Study
Additional Links
Substances : Nicotinamide, Riboflavin (Vitamin B-2), Thiamine (B-1)
Diseases : Allodynia, Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive , Chemoprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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