Cholangiocarcinoma

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70 Substances Researched for Cholangiocarcinoma
NameACCKFocus
Fruit: All220Locked
Green Tea220Locked
Vegetables: All 220Locked
Flavonoids514Locked
Omega-3 Fatty Acids211Locked
L-Carnitine110Locked
Polyphenols110Locked
Tea: Black110Locked
Cordyceps Militaris46Locked
Curcumin36Locked
Capsaicin15Locked
Cucurbitacin B 55Locked
Delta-tetrahydrocannabinol (THC)15Locked
Reishi Mushroom15Locked
Xanthohumol35Locked
Piperlongumine 44Locked
Watercress14Locked
EGCG (Epigallocatechin gallate)23Locked
Resveratrol23Locked
Shikonin33Locked
Allicin12Locked
Berberine22Locked
Diosgenin12Locked
Kiwifruit12Locked
Licorice22Locked
Lupeol12Locked
Stigmasterol12Locked
Thymoquinone12Locked
Tripterygium wilfordii22Locked
Triptolide22Locked
Vitamin D12Locked
Xanthones22Locked
Andrographis11Locked
Arctigenin11Locked
Artesunate11Locked
Asiatic Acid11Locked
Betulinic acid11Locked
Bromelain11Locked
Cannabidiol11Locked
Cannabigerol 11Locked
Cannabinoids 11Locked
Catechin 11Locked
Celastrol11Locked
Chlorella (Algae)11Locked
Curcumol11Locked
DHA (Docosahexaenoic Acid)11Locked
Elm tree11Locked
Eriodictyol11Locked
Fisetin11Locked
Fucoidan11Locked
Gallic Acid11Locked
Gold (nanoparticles)11Locked
Hesperidin11Locked
Honokiol11Locked
Horse Chestnut11Locked
Kaempferia parviflora11Locked
Magnolol11Locked
Moringa oleifera11Locked
Myricetin11Locked
Nobiletin 11Locked
Papain11Locked
Phenethyl isothiocyanate11Locked
Phyllanthus emblica11Locked
Piperine11Locked
Pterostilbene11Locked
Tannic Acid11Locked
Tanshinone IIA11Locked
Terminalia11Locked
Turmeric11Locked
Vitamin K11Locked
3 Problem Substances Researched for Cholangiocarcinoma
NameACCKFocus
Artificially Sweetened Beverages110Locked
Sugar Sweetened Beverages110Locked
Glyphosate11Locked
3 Therapeutic Actions Researched for Cholangiocarcinoma
NameACCKFocus
Dietary Modification: Low Carbohydrate120Locked
Dietary Modification: Low Glycemic Diet120Locked
Light-Emitting Diodes (LEDs) Therapy11Locked

View the Evidence:
89 Abstracts with Cholangiocarcinoma Research

[+]

Fruit and vegetables consumption is associated with Cholangiocarcinoma risk reduction.Sep 27, 2016

Pubmed Data : Nutr Cancer. 2016 Sep 28:1-6. Epub 2016 Sep 28. PMID: 27682423
Article Published Date : Sep 27, 2016
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Cholangiocarcinoma
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

Green tea consumption may lower the risk of biliary tract cancer, and the effect may be attributable to Sencha consumption.Nov 03, 2015

Pubmed Data : Cancer Sci. 2015 Nov 4. Epub 2015 Nov 4. PMID: 26530716
Article Published Date : Nov 03, 2015
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Cholangiocarcinoma
Additional Keywords : Risk Reduction
[+]

High consumption of sweetened beverages may increase the risk of biliary tract cancer and gallbladder cancer.Sep 30, 2016

Pubmed Data : J Natl Cancer Inst. 2016 Oct ;108(10). Epub 2016 Jun 8. PMID: 27281756
Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Diseases : Cholangiocarcinoma, Gallbladder Cancer
Additional Keywords : Increased Risk
Problem Substances : Artificially Sweetened Beverages, Sugar Sweetened Beverages
[+]

Increased fruit and vegetable consumption may decrease a risk of extrahepatic bile duct cancer.Oct 30, 2016

Pubmed Data : Int J Cancer. 2016 Oct 31. Epub 2016 Aug 31. PMID: 27798952
Article Published Date : Oct 30, 2016
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Cholangiocarcinoma, Gallbladder Cancer
Additional Keywords : Risk Reduction
[+]

l-carnitine is a good candidate to control oxidative stress conditions which is dysregulated in cholangiocarcinoma.Apr 24, 2016

Pubmed Data : Free Radic Res. 2016 Apr 25:1-12. Epub 2016 Apr 25. PMID: 27021847
Article Published Date : Apr 24, 2016
Study Type : Human Study
Additional Links
Substances : L-Carnitine
Diseases : Cholangiocarcinoma, Oxidative Stress
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Microbiome
[+]

Omega-3 fatty acid supplementation in patients with unresectable pancreatic and bile duct cancer may improve cancer cachexia.Dec 31, 2017

Pubmed Data : Anticancer Res. 2018 04 ;38(4):2369-2375. PMID: 29599363
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Bile Duct Cancer, Cachexia: Cancer, Pancreatic Cancer
Pharmacological Actions : Anti-Cachexic Agents
[+]

Tea consumption reduces the risk of biliary tract and gallbladder diseases.Nov 01, 2005

Pubmed Data : Zhonghua Zhong Liu Za Zhi. 2005 Nov;27(11):667-71. PMID: 16438888
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Substances : Flavonoids, Green Tea, Polyphenols, Tea: Black
Diseases : Bile Duct Cancer, Gallbladder Cancer
Pharmacological Actions : Chemopreventive
[+]

This data is consistent with the hypothesis that high glycemic load and index diets are associated with an increased risk of biliary tract cancer.May 31, 2016

Pubmed Data : Am J Gastroenterol. 2016 Jun ;111(6):891-6. Epub 2016 Mar 29. PMID: 27021191
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Diseases : Bile Duct Cancer, Cholangiocarcinoma
Therapeutic Actions : Dietary Modification: Low Carbohydrate, Dietary Modification: Low Glycemic Diet
Additional Keywords : Risk Factors, Risk Reduction
[+]

An extract of G. lucidum spores suppressed cholangiocarcinoma migration in vitro through inhibition of TGF-β1-induced EMT.May 14, 2016

Pubmed Data : Phytomedicine. 2016 May 15 ;23(5):491-7. Epub 2016 Mar 3. PMID: 27064008
Article Published Date : May 14, 2016
Study Type : Human In Vitro
Additional Links
Substances : Reishi Mushroom
Diseases : Cancer Metastasis, Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic
Additional Keywords : Plant Extracts
[+]

Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(5):e0121538. Epub 2015 May 1. PMID: 25933112
Article Published Date : Dec 31, 2014
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Capsaicin
Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Autophagy Inhibitors, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

THC inhibited cell proliferation, migration and invasion, and induced cell apoptosis in cholangiocarcinoma cells. Apr 30, 2010

Pubmed Data : Cancer Invest. 2010 May ;28(4):357-63. PMID: 19916793.
Article Published Date : Apr 30, 2010
Study Type : Human In Vitro
Additional Links
Substances : Delta-tetrahydrocannabinol (THC)
Diseases : Cancer Metastasis, Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
Additional Keywords : Dose Response
[+]

Curcumin analog WZ26 induces ROS and cell death.Dec 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Biol Ther. 2023 Dec 31 ;24(1):2162807. PMID: 36647192
Article Published Date : Dec 30, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

These data suggest that cordycepin can be used as a novel substance for the clinical treatment of cholangiocarcinoma and to improve the prognosis.Aug 14, 2023

Pubmed Data : Life Sci. 2023 Aug 15 ;327:121698. Epub 2023 Apr 18. PMID: 37080351
Article Published Date : Aug 14, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

25(OH)D is effective to repress human cholangiocarcinoma cell growth.Dec 31, 2015

Pubmed Data : Int J Mol Sci. 2016;17(8). Epub 2016 Aug 12. PMID: 27529229
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative
[+]

Allicin inhibits the proliferation and invasion in cholangiocarcinoma.May 21, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2018 May 22 ;47(2):641-653. Epub 2018 May 22. PMID: 29794468
Article Published Date : May 21, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Allicin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Curative effect of xanthohumol supplementation during liver fluke-associated cholangiocarcinogenesis.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2020 May ;10(3):230-235. Epub 2019 Feb 10. PMID: 32670817
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Xanthohumol
Diseases : Cholangiocarcinoma, Flukes
Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Autophagy Up-regulation
[+]

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.Sep 07, 2010

Pubmed Data : Int J Cancer. 2010 Sep 7. Epub 2010 Sep 7. PMID: 20824699
Article Published Date : Sep 07, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Proliferative, Chemopreventive, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Dietary intake of watercress may help reverse cisplatin resistance in biliary tract cancer patients.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Mar 1 ;7(9):10271-82. PMID: 26848531
Article Published Date : Feb 29, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Watercress
Diseases : Bile Duct Cancer, Cancers: Drug Resistant, Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Diosgenin was found to have efficient antitumor potential of human cholangiocarcinoma cells in vitro and in vivo.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2019 ;12:9093-9104. Epub 2019 Nov 4. PMID: 31806994
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Diosgenin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Hardy Kiwi) root extract exerts anti-cancer effects via Mcl-1-mediated apoptosis in cholangiocarcinoma.Dec 31, 2018

Pubmed Data : Nutr Cancer. 2019 ;71(2):246-256. Epub 2019 Jan 11. PMID: 30633583
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Kiwifruit
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic
[+]

Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(12):e0189628. Epub 2017 Dec 12. PMID: 29232409
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lupeol, Stigmasterol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents.May 10, 2010

Pubmed Data : Lab Invest. 2010 May 10. Epub 2010 May 10. PMID: 20458282
Article Published Date : May 10, 2010
Study Type : Animal Study
Additional Links
Diseases : Cholangiocarcinoma
Pharmacological Actions : Chemosensitizer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Thymoquinone possesses promising therapeutic potential as an anti-tumor agent for the treatment of hepatocellular carcinoma and cholangiocarcinoma.Nov 23, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Nov 24 ;23(23). Epub 2022 Nov 24. PMID: 36498999
Article Published Date : Nov 23, 2022
Study Type : In Vitro Study, Review
Additional Links
Substances : Thymoquinone
Diseases : Cholangiocarcinoma, Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Xanthohumol inhibits STAT3 activation pathway leading to growth suppression and apoptosis induction in human cholangiocarcinoma cells.Mar 31, 2016

Pubmed Data : Oncol Rep. 2016 Apr ;35(4):2065-72. Epub 2016 Jan 21. PMID: 26794001
Article Published Date : Mar 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, STAT3 Inhibitor
[+]

Enhancement of piperlongumine chemosensitivity by silencing heme oxygenase-1 expression in cholangiocarcinoma cell lines.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2020 Sep ;20(3):2483-2492. Epub 2020 Jun 26. PMID: 32782567
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Cholangiocarcinoma
Pharmacological Actions : Chemotherapeutic
[+]

Alcohol-associated liver cancer.Apr 11, 2024

Pubmed Data : Hepatology. 2024 Apr 12. Epub 2024 Apr 12. PMID: 38607725
Article Published Date : Apr 11, 2024
Study Type : Review
Additional Links
Diseases : Alcohol Toxicity , Cholangiocarcinoma, Liver Cancer
[+]

Andrographis paniculata extracts and major constituent diterpenoids inhibit growth of intrahepatic cholangiocarcinoma cells by inducing cell cycle arrest and apoptosis.Apr 30, 2014

Pubmed Data : Planta Med. 2014 May ;80(7):533-43. Epub 2014 Apr 29. PMID: 24782229
Article Published Date : Apr 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anti-metastatic potential of natural triterpenoid cucurbitacin B against cholangiocarcinoma cells.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2022 Jan-Dec;21:15347354221124861. PMID: 36154723
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Anticancer activity of fucoidan via apoptosis and cell cycle arrest on cholangiocarcinoma cell.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2021 Jan 1 ;22(1):209-217. Epub 2021 Jan 1. PMID: 33507701
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathwayDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Med. 2020 Jan ;9(2):783-796. Epub 2019 Nov 26. PMID: 31957323
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Celastrol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Arctigenin inhibits cholangiocarcinoma progression.Jul 19, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2021 Jul 20. Epub 2021 Jul 20. PMID: 34283274
Article Published Date : Jul 19, 2021
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Artesunate and chloroquine induce cytotoxic activity on cholangiocarcinoma cells via different cell death mechanisms.Jul 29, 2018

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2018 Jul 30 ;64(10):113-118. Epub 2018 Jul 30. PMID: 30084802
Article Published Date : Jul 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : Artesunate
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Cytotoxic
[+]

Baicalin induced apoptosis of human cholangiocarcinoma cell.Jun 30, 2022

Pubmed Data : Bull Exp Biol Med. 2022 Jul ;173(3):366-370. Epub 2022 Jul 20. PMID: 35854022
Article Published Date : Jun 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic
[+]

Bromelain and papain have cytotoxic effects on human cholangiocarcinoma cell lines.Apr 30, 2016

Pubmed Data : Int J Oncol. 2016 May ;48(5):2025-34. Epub 2016 Mar 1. PMID: 26935541
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Bromelain, Papain
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-Inflammatory Agents, Cytotoxic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

Cannabidiol and cannabigerol inhibit cholangiocarcinoma growth.Jan 19, 2022

Pubmed Data : Biomolecules. 2022 06 20 ;12(6). Epub 2022 Jun 20. PMID: 35740979
Article Published Date : Jan 19, 2022
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol, Cannabigerol , Cannabinoids
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation
[+]

Condensed tannins from leaves of U. pumila remarkably suppressed cholangiocarcinoma cell viability.Aug 19, 2022

Pubmed Data : J Food Biochem. 2022 Aug 20:e14374. Epub 2022 Aug 20. PMID: 35986624
Article Published Date : Aug 19, 2022
Study Type : In Vitro Study
Additional Links
Substances : Elm tree
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Cordycepin enhanced therapeutic potential of gemcitabine against cholangiocarcinoma.Apr 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2024 May 1 ;32(3):369-378. Epub 2024 Apr 9. PMID: 38589021
Article Published Date : Apr 30, 2024
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cholangiocarcinoma
Pharmacological Actions : Chemosensitizer
Additional Keywords : Cancer Stem Cells, Chemotherapeutic Synergy: Gemcitabine
[+]

Cordycepin inhibits cancer cell proliferation and angiogenesis in cholangiocarcinoma. Apr 30, 2020

Pubmed Data : J Pharmacol Exp Ther. 2020 May ;373(2):279-289. Epub 2020 Feb 26. PMID: 32102917
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative
[+]

Cordycepin sensitizes cholangiocarcinoma cells to be killed by natural killer-92 (NK-92) cells.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Oct 1 ;26(19). Epub 2021 Oct 1. PMID: 34641520
Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Cholangiocarcinoma
Pharmacological Actions : Chemosensitizer
[+]

Cucurbitacin B diminishes metastatic behaviour of cholangiocarcinoma cells.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2021 Jan 1 ;22(1):219-225. Epub 2021 Jan 1. PMID: 33507702
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Cucurbitacin B induces mitochondrial-mediated apoptosis pathway in cholangiocarcinoma cells.Feb 28, 2019

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2019 Mar ;392(3):271-278. Epub 2018 Nov 23. PMID: 30470919
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic
[+]

Cucurbitacin B might be a promising tratrment for cholangiocarcinoma treatment by targeting FAK protein.Dec 31, 2019

Pubmed Data : Am J Chin Med. 2020 ;48(6):1475-1489. Epub 2020 Sep 9. PMID: 32907364
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Tumor Suppressor Protein p53 Upregulation
[+]

Curcumin exhibits chemopreventive properties against cholangiocarcinoma cells.Aug 01, 2010

Pubmed Data : Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2265-72. Epub 2010 May 25. PMID: 20510329
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Chemopreventive, NF-kappaB Inhibitor
[+]

Curcumol exerts anticancer effect in cholangiocarcinoma cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2018 ;9:234. Epub 2018 Mar 20. PMID: 29615928
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Effect of betulinic acid extraction from Guava leaves against human cholangiocarcinoma cells.Jan 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2022 Feb 1 ;23(2):583-590. Epub 2022 Feb 1. PMID: 35225471
Article Published Date : Jan 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

EGCG sensitizes human cholangiocarcinoma cells to chemotherapy-induced programmed cell death. May 01, 2009

Pubmed Data : Liver Int. 2009 May;29(5):670-7. Epub 2009 Feb 17. PMID: 19226332
Article Published Date : May 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Catechin , EGCG (Epigallocatechin gallate)
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Chemosensitizer
Additional Keywords : Drug: 5-flourouracil, Drug: Mitomycin, Plant Extracts
[+]

EGCG significantly reduced cell viability of all eight BTC cell lines and for most cell lines a synergistic cytotoxic effect could be shown.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 ;15:194. Epub 2015 Jun 23. PMID: 26100134
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Bile Duct Cancer, Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Gene Expression Regulation
[+]

Eriodictyol attenuates cholangiocarcinoma malignancy.Jul 31, 2022

Pubmed Data : Anticancer Res. 2022 Aug ;42(8):3789-3798. PMID: 35896263
Article Published Date : Jul 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Galangin inhibits cholangiocarcinoma cell growth and metastasis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2020 ;2020:5846938. Epub 2020 Jun 11. PMID: 32626749
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , MicroRNA modulator
[+]

Gambogic acid and piperine synergistically induce apoptosis in human cholangiocarcinoma cell.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:6288742. Epub 2022 May 12. PMID: 35600948
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Piperine
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Gambogic acid inhibits Wnt/β-catenin signaling and induces ER stress-mediated apoptosis in human cholangiocarcinoma.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2021 Jun 1 ;22(6):1913-1920. Epub 2021 Jun 1. PMID: 34181351
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Xanthones
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Wnt/β-catenin signaling pathway modulation
[+]

Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells.Jun 07, 2018

Pubmed Data : Food Chem Toxicol. 2018 Jun 8 ;118:595-607. Epub 2018 Jun 8. PMID: 29890199
Article Published Date : Jun 07, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Cholangiocarcinoma, Glyphosate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Proliferative
[+]

Gold nanoparticles enhance the anticancer activity of gallic acid against cholangiocarcinoma cell lines.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(16):7143-7. PMID: 26514503
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid, Gold (nanoparticles)
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative
[+]

Hesperidin shows promise as a therapeutic agent for Intrahepatic cholangiocarcinoma treatment.Jan 03, 2022

Pubmed Data : J Biochem Mol Toxicol. 2022 Jan 4:e22981. Epub 2022 Jan 4. PMID: 34984768
Article Published Date : Jan 03, 2022
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Honokiol can effectively activate cholangiocarcinoma apoptosis and increase the release of damage-associated molecular patterns. Aug 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2019 Aug 7 ;25(29):3941-3955. PMID: 31413529
Article Published Date : Aug 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic
[+]

Kaempferia parviflora extract may have a role in the prevention and treatment of cholangiocarcinoma.Oct 01, 2009

Pubmed Data : Asian Pac J Cancer Prev. 2009 Oct-Dec;10(4):695-8. PMID: 19827897
Article Published Date : Oct 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Kaempferia parviflora
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

LED is a useful light source for deactivating the cancer cells because it can excite the sensitizers.Oct 20, 2017

Pubmed Data : Bioorg Med Chem. 2017 Oct 21. Epub 2017 Oct 21. PMID: 29108834
Article Published Date : Oct 20, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Cholangiocarcinoma
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
[+]

Licochalcone A induces cholangiocarcinoma cell death.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2022 Jan 1 ;23(1):115-123. Epub 2022 Jan 1. PMID: 35092379
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Licorice
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, NF-kappaB Inhibitor
[+]

Licochalcone A inhibits cell growth through the downregulation of the Hippo pathway via PES1 in cholangiocarcinoma cells.Nov 29, 2021

Pubmed Data : Environ Toxicol. 2021 Nov 30. Epub 2021 Nov 30. PMID: 34845814
Article Published Date : Nov 29, 2021
Study Type : In Vitro Study
Additional Links
Substances : Licorice
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative
[+]

Low dose berberine suppresses cholangiocarcinoma cell progression.Sep 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2022 Oct 1 ;23(10):3379-3386. Epub 2022 Oct 1. PMID: 36308362
Article Published Date : Sep 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Vascular Endothelial Growth Factor A Inhibitor
[+]

Magnolol could inhibit the growth, migration and invasion of cholangiocarcinoma cells through regulation of NF-κB pathway.Aug 01, 2017

Pubmed Data : Biomed Pharmacother. 2017 Aug 2 ;94:474-480. Epub 2017 Aug 2. PMID: 28779709
Article Published Date : Aug 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Magnolol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix Metalloproteinase-7 (MMP-7) Inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

Microalga Chlorella extract induced apoptotic cell death of cholangiocarcinoma.Mar 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2023 Apr ;160:114306. Epub 2023 Feb 2. PMID: 36738497
Article Published Date : Mar 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

MicroRNA-455-5p contributes to cholangiocarcinoma growth and mediates galangin's anti-tumor effects.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer. 2021 ;12(15):4710-4721. Epub 2021 Jun 4. PMID: 34149934
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Cholangiocarcinoma
Pharmacological Actions : Chemotherapeutic
[+]

Myricetin ameliorates cytokine-induced migration and invasion of cholangiocarcinoma cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Res Ther. 2019 Jan-Mar;15(1):157-163. PMID: 30880773
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Myricetin
Diseases : Cancer Metastasis, Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, STAT3 Inhibitor
[+]

Nobiletin suppresses cholangiocarcinoma proliferation via inhibiting GSK3β.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biol Sci. 2022 ;18(15):5698-5712. Epub 2022 Sep 11. PMID: 36263164
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Nobiletin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Omega-3 fatty acids block cholangiocarcinoma cell growth. Jan 15, 2008

Pubmed Data : Cancer Res. 2008 Jan 15;68(2):553-60. PMID: 18199552
Article Published Date : Jan 15, 2008
Study Type : In Vitro Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), Omega-3 Fatty Acids
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Cyclooxygenase 2 Inhibitors
[+]

Piperlongumine and bortezomib synergically inhibit cholangiocarcinoma.Oct 12, 2022

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2022 Oct 13. Epub 2022 Oct 13. PMID: 36227332
Article Published Date : Oct 12, 2022
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Natural Substance/Drug Synergy
[+]

Piperlongumine induces autophagy in biliary cancer cells via reactive oxygen species-activated Erk signaling pathway.Aug 22, 2019

Pubmed Data : Int J Mol Med. 2019 Aug 23. Epub 2019 Aug 23. PMID: 31485612
Article Published Date : Aug 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Cholangiocarcinoma, Gallbladder Cancer
Pharmacological Actions : Autophagy Up-regulation, Chemotherapeutic
[+]

Piperlongumine induces phase arrest and apoptosis in cholangiocarcinoma cells.Sep 13, 2017

Pubmed Data : Apoptosis. 2017 Sep 14. Epub 2017 Sep 14. PMID: 28913568
Article Published Date : Sep 13, 2017
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Potential of alpha-mangostin-loaded PLGA nanoparticles for cholangiocarcinoma treatment.Oct 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Polymers (Basel). 2022 Oct 20 ;14(20). Epub 2022 Oct 20. PMID: 36298022
Article Published Date : Oct 19, 2022
Study Type : In Vitro Study
Additional Links
Substances : Xanthones
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Pterostilbene suppresses proliferation potential of human cholangiocarcinoma.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:1238. Epub 2019 Oct 22. PMID: 31695612
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Autophagy Up-regulation, Cell cycle arrest
Additional Keywords : Dose Response
[+]

Resveratrol inhibits cell growth in a human cholangiocarcinoma cell line. Dec 01, 2008

Pubmed Data : Liver Int. 2008 Dec;28(10):1426-36. Epub 2008 Apr 5. PMID: 18397227
Article Published Date : Dec 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Bile Duct Cancer, Cholangiocarcinoma
[+]

Resveratrol interrupts the pro-invasive communication between cancer associated fibroblasts and cholangiocarcinoma cells.Aug 27, 2018

Pubmed Data : Cancer Lett. 2018 Aug 28 ;430:160-171. Epub 2018 May 23. PMID: 29802929
Article Published Date : Aug 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic, Interleukin-6 Downregulation
[+]

Shikonin could inhibit cell viability and induce apoptosis in cholangiocarcinoma cells.Jun 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2017 Jun 29 ;42(3):1073-1086. Epub 2017 Jun 29. PMID: 28662515
Article Published Date : Jun 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Shikonin inhibits cholangiocarcinoma cell line QBC939.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Transplant. 2021 Jan-Dec;30:963689720979162. PMID: 33508949
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Shikonin may be a novel therapeutic agent for patients with cholangiocarcinoma.Aug 31, 2020

Pubmed Data : Anticancer Res. 2020 Sep ;40(9):5115-5124. PMID: 32878800
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Suppression of glutathione S-transferases potentiates the cytotoxic effect of phenethyl isothiocyanate in cholangiocarcinoma cells.Apr 16, 2018

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2018 Apr 17. Epub 2018 Apr 17. PMID: 29666895
Article Published Date : Apr 16, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Cholangiocarcinoma
Pharmacological Actions : Cytotoxic
[+]

Tannic acid synergizes the cytotoxicity of chemotherapeutic drugs in human cholangiocarcinoma.Jan 31, 2007

Pubmed Data : J Hepatol. 2007 Feb ;46(2):222-9. Epub 2006 Oct 6. PMID: 17069924
Article Published Date : Jan 31, 2007
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemotherapeutic Synergy: Gemcitabine, Chemotherapeutic Synergy: Mitomycin C
[+]

Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells.Sep 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Sep 29 ;11(1):19268. Epub 2021 Sep 29. PMID: 34588580
Article Published Date : Sep 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative
[+]

The molecular mechanisms of cholangiocarcinoma cell inhibition by medicinal plants.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Feb ;13(2):961-966. Epub 2016 Dec 12. PMID: 28356985
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Moringa oleifera, Phyllanthus emblica, Terminalia, Turmeric
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

The role of herbal medicine in cholangiocarcinoma control.Apr 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Planta Med. 2022 Apr 25. Epub 2022 Apr 25. PMID: 35468650
Article Published Date : Apr 24, 2022
Study Type : Review
Additional Links
Substances : Cucurbitacin B
Diseases : Cholangiocarcinoma
Pharmacological Actions : Chemotherapeutic
[+]

These results highlight the potential of berberine to be a multi-target agent for cholangiocarcinoma treatment.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2017 ;40(6):751-757. PMID: 28566619
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Cell cycle arrest, NF-kappaB Inhibitor
Additional Keywords : Dose Response
[+]

These results showed the chemotherapeutic activities of asiatic acid against Cholangiocarcinoma.Jul 29, 2018

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2018 Jul 30 ;64(10):28-33. Epub 2018 Jul 30. PMID: 30084792
Article Published Date : Jul 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : Asiatic Acid
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic
[+]

These results suggest fisetin in combination with gemcitabine as a candidate for use in improved anticancer regimens.Jan 10, 2016

Pubmed Data : Anticancer Res. 2016 11 ;36(11):6109-6116. PMID: 27793939
Article Published Date : Jan 10, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fisetin, Flavonoids
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic
Additional Keywords : Antiproliferative, Apoptotic, Chemotherapeutic, Chemotherapeutic Synergy: Gemcitabine, Cholangiocarcinoma, Fisetin, Flavonoids
[+]

Triptolide, a compound found within Tripterygium wilfordii, has a synergistic effect with TNF-alpha against cholangiocarcinoma. Sep 01, 2002

Pubmed Data : Asian Pac J Allergy Immunol. 2002 Sep;20(3):167-73. PMID: 12587840
Article Published Date : Sep 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Tripterygium wilfordii, Triptolide
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Triptolide, a compound found within Tripterygium wilfordii, sensitizes cholangiocarcinoma cells to programmed cell death. Jan 01, 2006

Pubmed Data : Anticancer Res. 2006 Jan-Feb;26(1A):259-65. PMID: 16475706
Article Published Date : Jan 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Tripterygium wilfordii, Triptolide
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic, Chemosensitizer, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Vitamin K2 inhibits cell growth in cholangiocellular carcinoma cell lines. Dec 01, 2007

Pubmed Data : Int J Mol Med. 2007 Dec;20(6):801-8. PMID: 17982686
Article Published Date : Dec 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K
Diseases : Cholangiocarcinoma
Pharmacological Actions : Apoptotic, Cell cycle arrest
[+]

Xanthohumol significantly reduced cholangiocarcinoma growth.Oct 19, 2017

Pubmed Data : Oncotarget. 2017 Oct 20 ;8(50):88069-88078. Epub 2017 Sep 30. PMID: 29152142
Article Published Date : Oct 19, 2017
Study Type : In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

β-escin reverses multidrug resistance through inhibition of the GSK3β/β-catenin pathway in cholangiocarcinoma.Jan 27, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2015 Jan 28 ;21(4):1148-57. PMID: 25632187
Article Published Date : Jan 27, 2015
Study Type : In Vitro Study
Additional Links
Substances : Horse Chestnut
Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Cholangiocarcinoma
Pharmacological Actions : Antiproliferative , Chemosensitizer

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