Cholesterol: Oxidation

Name	AC	CK
Polyphenols	9	65
Flavonoids	13	61
Vitamin E	4	31
Catechin	3	30
Coenzyme Q10	5	24
Curcumin	11	24
Olive Oil	4	22
Broccoli Sprouts	2	20
Fermented Foods and Beverages	2	20
Vitamin C	7	17
Olive	5	14
Cranberry	3	13
Almond	2	12
Sea buckthorn	2	12
Genistein	2	11
Quercetin	2	11
Strawberry	2	11
B-complex	1	10
Barley Grass	1	10
Carnitine	1	10
Cayenne	1	10
Chili pepper	1	10
Chocolate	1	10
Daidzein	1	10
EPA (Eicosapentaenoic Acid)	1	10
Flaxseed	1	10
Ginseng (Korean)	1	10
Goat Milk	1	10
Guggul	1	10
Isoflavones	1	10
Licorice	1	10
Lignans	1	10
Lycopene	1	10
Orange	1	10
Pecan	1	10
Phytosterols	1	10
Pomegranate	1	10
Resveratrol	7	10
Soy	1	10
Soy Protein	1	10
Ubiquinol	1	10
Mustard: Field/Turnip	2	6
Honey	1	5
Nobiletin	1	5
Puerarin	1	5
Astaxanthin	2	4
Banana	2	4
Rice: Black	2	4
Turmeric	2	4
Alpha-Lipoic Acid	3	3
Capsaicin	2	3
Oleuropein	3	3
Anthocyanins	1	2
Blue Honeysuckle	1	2
Broccoli	1	2
Carnosine	1	2
Flowers	1	2
Folate: Dietary	1	2
Hawthorn	1	2
Histidine	1	2
Hydroxytyrosol	2	2
Kaempferol	2	2
Ligustrazine	1	2
Oats	1	2
P-Coumaric Acid	1	2
Paeonol	2	2
Pine Needle	1	2
Pistachio nut	1	2
Plantain	1	2
Red Wine Extract	1	2
Rice: Brown	1	2
Stilbenes	2	2
Tanshinone IIA	2	2
Vegetables: All	1	2
6-Shogaol	1	1
Argania spinosa (Argan)	1	1
Baicalein	1	1
Beans: All	1	1
Berberine	1	1
Blueberry	1	1
Caffeic Acid	1	1
Celery seed	1	1
Cherry: All Varieties	1	1
Dates	1	1
Dihydrocapsaicin	1	1
EGCG (Epigallocatechin gallate)	1	1
Fo ti	1	1
Ginger	1	1
Ginkgo biloba	1	1
Ginsenosides	1	1
Grape	1	1
Grape Seed Extract	1	1
Honokiol	1	1
Luteolin	1	1
Maqui	1	1
Naringenin	1	1
Nutmeg	1	1
Oregano	1	1
Prickly Pear Cactus	1	1
Schisandra	1	1
Thyme	1	1
Vitexins	1	1
Horehound	1	0

Name	AC	CK
Lovastatin	2	12
Statin Drugs	2	12
Acrylamide	1	10
Dl-alpha-tocopherol acetate	1	10
Potato	1	10
Potato Chips	1	10

Name	AC	CK	Focus
Dietary Modification: Mediterranean Diet	3	12
Exercise	2	12

Name	AC	CK
Vaccination: All	1	10
Vaccination: Influenza	1	10
Microwave Cooking	2	3
Gamma Irradiation: "Cold Pasteurization"	1	2

[+]

A 10-month exercise program reduces oxidized LDL levels. Oct 01, 1998

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Pubmed Data : Med Sci Sports Exerc. 1998 Oct;30(10):1496-501. PMID: 9789849

Article Published Date : Oct 01, 1998

Study Type : Human Study

Additional Links

Diseases : Arteriosclerosis, Cholesterol: Oxidation

Pharmacological Actions : Antioxidants

[+]

A Mediterranean diet reduces LDL oxidation. Jun 11, 2007

Article Published Date : May 31, 2012

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts

Diseases : Cardiovascular Disease: Prevention, Cholesterol: Oxidation, Diabetes Mellitus: Type 2, Oxidative Stress

Pharmacological Actions : Anticholesteremic Agents, Antioxidants

Additional Keywords : Phytotherapy, Risk Reduction

[+]

Broccoli sprouts powder led to a significant decrease in oxidative stress and oxidized low density lipoprotein cholesterol in type 2 diabetes patients.Jul 31, 2011

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2011 Aug ;65(8):972-7. Epub 2011 May 11. PMID: 21559038

Article Published Date : Jul 31, 2011

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts

Diseases : Cholesterol: Oxidation, Diabetes Mellitus: Type 2, Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

Additional Keywords : Dose Response, Phytotherapy

[+]

Chronic ingestion of acrylamide-containing products (potato chips) induces a proinflammatory state, a risk factor for progression of atherosclerosis.Mar 01, 2009

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2009 Mar ;89(3):773-7. Epub 2009 Jan 21. PMID: 19158207

Click here to read the entire abstract

Pubmed Data : J Nutr. 2015 Jul 1. Epub 2015 Jul 1. PMID: 26136585

Guggul may be beneficial against atherogenesis via lipid lowering and inhibition of LDL oxidation.Feb 01, 2004

Click here to read the entire abstract

Pubmed Data : Atherosclerosis. 2004 Feb;172(2):239-46. PMID: 15019533

Article Published Date : Feb 01, 2004

Study Type : Human Study

Additional Links

Substances : Guggul

Diseases : Arteriosclerosis, Cholesterol: Oxidation, High Cholesterol

[+]

Highly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Chron Obstruct Pulmon Dis. 2016 ;11:2029-34. Epub 2016 Aug 26. PMID: 27616885

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Atherosclerosis, Cholesterol: Oxidation, Chronic Obstructive Pulmonary Disease

Pharmacological Actions : Anti-Inflammatory Agents, Anticholesteremic Agents

[+]

Korean red ginseng supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.Jul 16, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2012 Jul 17 ;11:47. Epub 2012 Jul 17. PMID: 22805313

Article Published Date : Jul 16, 2012

Click here to read the entire abstract

Pubmed Data : Antioxid Redox Signal. 2000 Fall;2(3):491-506. PMID: 11229363

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Pubmed Data : Nutrition. 2009 Oct 6. Epub 2009 Oct 6. PMID: 19815390

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Pubmed Data : Metabolism. 2008 Dec;57(12):1636-44. PMID: 19013285

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Strawberry

Diseases : Cholesterol: Oxidation, Hyperlipidemia

[+]

The Mediterranean diet, which includes a combination of antioxidant compounds and flavonoid-rich foods, appears effective to decrease LDL particle oxidizability, which reduces the risk for cardiovascular disease. Oct 01, 2006

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2006 Oct;17(10):645-58. Epub 2006 Feb 3. PMID: 16517144

Article Published Date : Oct 01, 2006

Study Type : Human Study

Additional Links

Substances : Flavonoids, Polyphenols

Diseases : Arteriosclerosis, Cardiovascular Diseases, Cholesterol: Oxidation

Therapeutic Actions : Dietary Modification: Mediterranean Diet

Pharmacological Actions : Antioxidants

[+]

The percentage of EPA in the fatty acid composition of serum phospholipids is inversely correlated with levels of anti-oxidized-LDL antibodies. Sep 01, 2008

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Pubmed Data : Br J Nutr. 2008 Sep;100(3):585-9. Epub 2008 Feb 6. PMID: 18252023

Brown and black rice have cardioprotective effects.Jan 01, 2006

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Pubmed Data : Ann Nutr Metab. 2006;50(4):347-53. Epub 2006 Jun 28. PMID: 16809902

Article Published Date : Jan 01, 2006

Study Type : Animal Study

Additional Links

Substances : Rice: Black , Rice: Brown

Diseases : Cardiovascular Diseases, Cholesterol: Oxidation

Pharmacological Actions : Antioxidants, Cardioprotective

[+]

C. aronia inhibits high fat diet-induced vascular inflammation.Nov 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharm Biol. 2019 Dec ;57(1):38-48. PMID: 30702358

Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells which are associated wtih liver fibrosis. Nov 01, 2009

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Pubmed Data : Lab Invest. 2009 Nov;89(11):1275-90. Epub 2009 Sep 7. PMID: 19736547

Article Published Date : Nov 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cholesterol: Oxidation, Liver Fibrosis

Pharmacological Actions : Hepatoprotective

[+]

Daily consumption of an antioxidant-rich leafy vegetable mix (LVM) was assessed for beneficial effects on plasma lipid profiles, tissue lipid peroxidation, and oxidative DNA damage in mice fed a high fat and high cholesterol dietAug 01, 2009

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Pubmed Data : J Med Food. 2009 Aug;12(4):877-84. PMID: 19735190

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Pubmed Data : Cont Lens Anterior Eye. 2008 Jun;31(3):141-6; quiz 170. Epub 2008 Mar 4. PMID: 15878720

Article Published Date : Jun 01, 2008

Study Type : Animal Study

Additional Links

Substances : Carnosine, Histidine

Diseases : Cholesterol: Oxidation, Diabetes: Cardiovascular Illness, Diabetes: Glycation/A1C

Pharmacological Actions : Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Irradiation of meat results in the formation of choleserol oxides. Jan 01, 2001

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Pubmed Data : Poult Sci. 2001 Jan ;80(1):105-8. PMID: 11214329

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Pubmed Data : J Nutr. 2003 Mar;133(3):744-51. PMID: 12612147

Article Published Date : Mar 01, 2003

Study Type : Animal Study

Additional Links

Substances : Rice: Black

Diseases : Arterial Plaque, Arteriosclerosis, Cholesterol: Oxidation

[+]

Tetramethylpyrazine suppresses lipid accumulation in macrophages.Sep 30, 2017

A-lipoic acid may have a beneficial role in protecting against oxidation of LDL associated with cardiovascular disease. Jun 01, 2012

Click here to read the entire abstract

Pubmed Data : J Diet Suppl. 2012 Jun ;9(2):116-27. PMID: 22607646

Pubmed Data : Can J Physiol Pharmacol. 2007 Sep ;85(9):918-27. PMID: 18066138

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Oct 20. Epub 2016 Aug 20. PMID: 27776344

Article Published Date : Oct 19, 2016

Study Type : In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Atherosclerosis, Cholesterol: Oxidation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Atherosclerosis, Baicalein, Cholesterol: Oxidation

[+]

Berberine inhibits modified LDL-induced Müller cell injury by activating the AMPK pathway.May 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Appl Environ Microbiol. 2008 Jul;74(14):4564-6. Epub 2008 May 23. PMID: 18430363

Article Published Date : Jul 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Atherosclerosis, Cholesterol: Oxidation

[+]

Curcumin may inhibit oxidative stress including LDL cholesterol oxidation.Oct 01, 2010

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Pubmed Data : J Enzyme Inhib Med Chem. 2010 Oct;25(5):720-9. PMID: 20163327

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Pubmed Data : Cardiovasc Pathol. 2017 Aug 10 ;31:57-62. Epub 2017 Aug 10. PMID: 28985493

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Pubmed Data : Int J Vitam Nutr Res. 2005 Jan;75(1):61-70. PMID: 15830923

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Hydroxytyrosol, Oleuropein, Olive Oil

Diseases : Arteriosclerosis, Cholesterol: Oxidation

Pharmacological Actions : Antioxidants, Vascular Cell Adhesion Molecule-1 Inhibitor

[+]

Oregano and thyme extract prevents copper-induced oxidation of human low-density lipoproteins. Mar 01, 2007

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Pubmed Data : Int J Food Sci Nutr. 2007 Mar;58(2):87-93. PMID: 17469764

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Cytokine. 2018 11 ;111:475-480. Epub 2018 Jun 18. PMID: 29914794

Article Published Date : Jan 10, 2018

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Atherosclerosis, Cholesterol: Oxidation, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Pinocembrin suppresses oxidized low-density lipoprotein-triggered NLRP3 inflammasome/GSDMD-mediated endothelial cell pyroptosis.Aug 15, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Biochem Pharmacol. 1997 May 9;53(9):1347-55. PMID: 9214696

Article Published Date : May 09, 1997

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids, Resveratrol, Stilbenes

Diseases : Cholesterol: Oxidation, Copper Toxicity, Lipid Peroxidation

Pharmacological Actions : Anticarcinogenic Agents, Metal Chelation: Copper

Additional Keywords : Ldl Oxidation, Ox-ldl

[+]

Resveratrol Pharmokinetics: Interaction of trans-resveratrol with plasma lipoproteins. Resveratrol exhibits lipophilic characteristics.Mar 15, 1998

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Pubmed Data : Biochem Pharmacol. 1998 Mar 15;55(6):811-6. PMID: 9586953

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Pubmed Data : Arch Pharm Res. 2013 Apr ;36(4):423-9. Epub 2013 Feb 24. PMID: 23435947

View the Evidence: 146 Abstracts with Cholesterol: Oxidation Research

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A 10-month exercise program reduces oxidized LDL levels. Oct 01, 1998

A Mediterranean diet reduces LDL oxidation. Jun 11, 2007

A single dose of proanthocyanidins reduced LDL concentration and increased plasma adiponectin after 24 hours.Mar 01, 2017

Abnormalities in arterial function and LDL oxidation may persist for at least 2 weeks after a slight inflammatory reaction induced by influenza vaccination.Jan 01, 2007

Acute prolonged exercise reduces moderately oxidized LDL in healthy men.Jul 01, 2005

Almonds reduce biomarkers of lipid peroxidation in older hyperlipidemic subjects.May 01, 2008

Alpha-tocopherol supplementation decreases the oxidative susceptibility of LDL in renal failure patients on dialysis therapy.May 01, 2000

Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins.Jul 01, 2003

Broccoli sprout powder supplemention in type 2 diabetes could have favorable effects on lipid profiles and OX-LDL/LDL ratioMay 31, 2012

Broccoli sprouts powder led to a significant decrease in oxidative stress and oxidized low density lipoprotein cholesterol in type 2 diabetes patients.Jul 31, 2011

Chronic ingestion of acrylamide-containing products (potato chips) induces a proinflammatory state, a risk factor for progression of atherosclerosis.Mar 01, 2009

Cocoa inhibits LDL oxidation both in vitro and ex vivo.Apr 06, 1999

Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility and increasing serum total antioxidant capacity and HDL-cholesterol concentrations.Nov 01, 2001

Consumption of olive oil polyphenols decreased plasma LDL concentrations and LDL atherogenicity in healthy young men.Jun 30, 2015

Consumption of orange fermented beverage improves antioxidant status and reduces peroxidation lipid and inflammatory markers.Apr 30, 2018

Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.Jun 02, 2009

Cranberry juice supplementation reduces cholesterol oxidation and cell adhesion molecule concentrations in men. Feb 01, 2008

Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.Dec 01, 2008

Dietary chilli prevents serum lipoprotein oxidation in adult men and women.Aug 01, 2006

Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation.Jun 26, 1992

Dl-alpha-tocopherol acetate does not reduce the progression of atherosclerosis in healthy individuals. Sep 17, 2002

Glabridin, a compound found within licorice, inhibits LDL oxidation. May 01, 2009

Guggul may be beneficial against atherogenesis via lipid lowering and inhibition of LDL oxidation.Feb 01, 2004

Highly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD.Dec 31, 2015

Korean red ginseng supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.Jul 16, 2012

L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes.Jan 01, 2009

Lignan content of the flaxseed influences its biological effects in healthy men and women.May 31, 2013

Lovastatin enhances the susceptibility of LDL cholesterol to oxidation.Jun 30, 1997

Lycopene contributes to the inhibition of LDL oxidation. Sep 01, 2000

Olive oil consumption reduces the susceptibility of LDL to oxidation, supporting the hypothesis that daily virgin olive oil intake protects cardiovascular health. Dec 01, 2007

Pecans acutely increase plasma postprandial antioxidant capacity and catechins and decrease LDL oxidation in humans.Jan 01, 2011

Phytosterols inhibit copper lipid peroxidation of human low-density lipoproteins.Oct 06, 2009

Pomegranate reduces the intima media thickness size of the artery, while also reducing blood pressure and LDL oxidation.Jun 01, 2004

Probiotic fermented goat's milk decreases oxidative stress-mediated atherogenicity in human subjects. Aug 01, 2003

Quercetin reduced systolic blood pressure and plasma oxidised LDL concentrations in overweight subjects with a high-cardiovascular risk phenotype.Oct 01, 2009

Sea Buckthorn inhibits LDL oxidationJun 01, 2002

Serum oxidized low-density lipoprotein is inversely correlated to telomerase activity in peripheral blood mononuclear cells of haemodialysis patients..Dec 01, 2006

Soy consumption reduces plasma coagulation factor IX activity, which is a risk factor for thrombosis in peritoneal dialysis patients.Sep 01, 2009

Soy protein reduces cholesterol oxidation in patients on hemodialysis. Jan 01, 2006

Strawberry supplementation reduces oxidative damage to LDL while reducing blood lipids.Dec 01, 2008

The Mediterranean diet, which includes a combination of antioxidant compounds and flavonoid-rich foods, appears effective to decrease LDL particle oxidizability, which reduces the risk for cardiovascular disease. Oct 01, 2006

The percentage of EPA in the fatty acid composition of serum phospholipids is inversely correlated with levels of anti-oxidized-LDL antibodies. Sep 01, 2008

There is an association between cholesterol oxidation and Cystic Fibrosis. Sep 01, 2009

These results provide for the first time a first-level evidence of an enhancement in HDL function by polyphenol-rich olive oil.Aug 31, 2014

Vitamin C may contribute to reducing cholesterol oxidation and C-reactive protein. Nov 01, 2008

Young barley grass leaf extract attenuates LDL oxidation and decreases plasma lipids in hyperlipidemic smokers and/or non-smokers. Jun 01, 2004

Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro).Feb 28, 2009

Puerarin possessed certain anticoagulation and may be a potential novel therapeutic drug for thrombosis in coronary artery disease.Dec 14, 2017

These data suggest that nobiletin might be a potential antithrombotic agent of dietary origin.Mar 14, 2017

Cardiovascular protective effect of glabridin: Implications in LDL oxidation and inflammation.Nov 30, 2015

A broccoli extract enriched diet increases antioxidant enzyme activities and exerts an antioxidant effect towards cholesterol oxidation in rat liver.Apr 11, 2016

Almonds and almond oil have similar positive effects on plasma lipids and LDL oxidation in healthy men and women.Apr 01, 2002

Andrographolide inhibits oxidized LDL-induced cholesterol accumulation and foam cell formation in macrophages.Dec 31, 2017

Astaxanthin ameliorates endothelial dysfunction in diabetic rats.Jan 01, 2011

Astaxanthin prevented hypercholesterolemia-induced protein oxidation and protein oxidation per se. Jun 30, 2012

Banana flowers have a blood sugar lowering effect in a type 1 diabetes model.Sep 01, 2002

Banana prevents lipid oxidation in rats.Dec 01, 2005

Blue honeysuckle extract protects human endothelial cells and rat livers from oxidative stress.Aug 11, 2009

Brown and black rice have cardioprotective effects.Jan 01, 2006

C. aronia inhibits high fat diet-induced vascular inflammation.Nov 30, 2019

Cherries contain anthocyanins which prevent lipid peroxidation and inhibit pro-inflammatory cycloxygenase enzymes.Feb 25, 2009

Coenzyme Q10 exhibits anti-atherogenic activity in mice. Aug 01, 2000

Compounds in oats are bioavailable and act synergistically with vitamin C enhance hamster and human LDL resistance to oxidation.Jun 01, 2004

Cranberry powder has a favorable effect on blood lipid profiles and antoxidant status in rats fed an atherogenic diet. Jan 01, 2008

Curcumin ameliorates aflatoxin-induced lipid-peroxidation in liver and kidney of mice.Mar 01, 2008

Curcumin and capsaicin individually are protective to LDL oxidation both in vivo and in vitro, to iron-induced hepatotoxicity and to carrageenan-induced inflammation.Aug 26, 2009

Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells which are associated wtih liver fibrosis. Nov 01, 2009

Daily consumption of an antioxidant-rich leafy vegetable mix (LVM) was assessed for beneficial effects on plasma lipid profiles, tissue lipid peroxidation, and oxidative DNA damage in mice fed a high fat and high cholesterol dietAug 01, 2009

Extra virgin olive oil is a daily functional food capable to enhance the antioxidant system for liver protection.Sep 01, 2016

Folic acid supplementation prevents VLDL and LDL oxidation which may contribute to the prevention of atherosclerosis.Jan 01, 2007

Histidine and carnosine delay diabetic deterioration in mice and protect human low density lipoprotein against oxidation and glycation.Jun 01, 2008

Irradiation of meat results in the formation of choleserol oxides. Jan 01, 2001

Cholesterol: Oxidation

View the Evidence:
146 Abstracts with Cholesterol: Oxidation Research