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30 Substances Researched for Clotting
NameACCKFocus
Policosanol330Locked
Flavonoids423Locked
Echinacea110Locked
Kiwifruit110Locked
Nattokinase110Locked
Olive110Locked
Onion110Locked
Prickly Pear Cactus110Locked
Vitamin K110Locked
Wintergreen110Locked
Resveratrol33Locked
Catechin 12Locked
Ginkgo biloba12Locked
Parsley12Locked
Yucca22Locked
Apigenin11Locked
Carrot11Locked
Cinnamon11Locked
Fennel11Locked
Fucoidan11Locked
Marjoram11Locked
Oleuropein11Locked
Olive leaf extract11Locked
Polyphenols11Locked
Resveratrol: Cis- Form11Locked
Savory11Locked
Shiitake Mushroom 11Locked
Stilbenes11Locked
Tarragon11Locked
Wasabi11Locked
3 Problem Substances Researched for Clotting
NameACCKFocus
Raloxifene110Locked
Concanavalin A11Locked
Wheat Germ Agglutinin (WGA)11Locked
2 Therapeutic Actions Researched for Clotting
NameACCKFocus
Dietary Modification: Mediterranean Diet211Locked
Yoga110Locked

View the Evidence:
34 Abstracts with Clotting Research

[+]

An onion-olive-oil combination reduces arterial blood pressure, plasma viscosity and hematocrit, indicating the cardiovascular benefits of a Mediterranean diet. Sep 01, 2000

Pubmed Data : Arzneimittelforschung. 2000 Sep;50(9):795-801. PMID: 11050695
Article Published Date : Sep 01, 2000
Study Type : Human Study
Additional Links
Substances : Olive, Onion
Diseases : Blood Coagulation Disorders, Clotting, Hypertension
Therapeutic Actions : Dietary Modification: Mediterranean Diet
[+]

Casual chocolate consumption results in anti-platelet effects.Jan 01, 2007

Pubmed Data : Prev Cardiol. 2007;10(4):175-80. PMID: 17917513
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-Platelet
[+]

Dark chocolate improves coronary vasomotion and reduces platelet reactivity.Nov 20, 2007

Pubmed Data : Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID: 17984375
Article Published Date : Nov 20, 2007
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Blood Platelet Disorders, Clotting, Coronary Artery Disease, Endothelial Dysfunction
Pharmacological Actions : Anti-Platelet, Vasodilator Agents
[+]

Echinacea significantly reduced plasma concentrations of S-warfarin. However, neither echinacea nor policosanol significantly affected warfarin pharmacodynamics, platelet aggregation or baseline clotting status in healthy subjects.Jul 19, 2006

Pubmed Data : J Ethnopharmacol. 2006 Jul 19;106(3):321-6. Epub 2006 Mar 6. PMID: 20573086
Article Published Date : Jul 19, 2006
Study Type : Human Study
Additional Links
Substances : Echinacea, Policosanol
Diseases : Clotting
Additional Keywords : Drug Interaction
[+]

Kiwifruit consumption reduces platelet aggregation and blood triglycerides in human subjects. May 01, 2010

Pubmed Data : J Altern Complement Med. 2010 May;16(5):555-60. PMID: 15370099
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Substances : Kiwifruit
Diseases : Cardiovascular Diseases, Clotting, Triglycerides: Elevated
Pharmacological Actions : Anti-Platelet, Platelet Aggregation Inhibitors
Additional Keywords : Plant Extracts
[+]

Nattokinase decreases plasma levels of fibrinogen, factor VII and factor VIII in human subjects. Mar 01, 2009

Pubmed Data : Nutr Res. 2009 Mar;29(3):190-6. PMID: 19358933
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Nattokinase
Diseases : Clotting, Thrombosis
[+]

One week of dark chocolate ingestion improved lipid profiles and decreased platelet reactivity within the total group while reducing inflammation only in women.Jul 01, 1999

Pubmed Data : Neurotoxicol Teratol. 1999 Jul-Aug;21(4):349-57. PMID: 19005437
Article Published Date : Jul 01, 1999
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : C-Reactive Protein, Clotting, Thrombosis
[+]

Opuntia may benefit heart health by decreasing platelet activity.Jul 01, 2003

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2003 Jul;69(1):61-6. PMID: 12878452
Article Published Date : Jul 01, 2003
Study Type : Human Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Clotting
Pharmacological Actions : Anti-Platelet
[+]

Policosanol (20 mg day) is as effective as aspirin (100 mg day) as a platelet aggregation inhibitor.Oct 01, 1997

Pubmed Data : Pharmacol Res. 1997 Oct;36(4):293-7. PMID: 9425618
Article Published Date : Oct 01, 1997
Study Type : Human Study
Additional Links
Substances : Policosanol
Diseases : Blood Coagulation Disorders, Clotting
Pharmacological Actions : Platelet Aggregation Inhibitors
Additional Keywords : Aspirin Alternatives, Natural Substances Versus Drugs
[+]

Policosanol is superior to Lipitor (atorvastatin) in improving blood lipid profiles and inhibiting platelet aggregation.Jan 01, 2003

Pubmed Data : Clin Drug Investig. 2003;23(10):639-50. PMID: 17535079
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Policosanol
Diseases : Clotting, Dyslipidemias, Thrombosis
Pharmacological Actions : Anti-Platelet
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Raloxifene enhances spontaneous microaggregation of platelets, associated with pathological thrombus (clot) formation. Jan 01, 2010

Pubmed Data : Osteoporos Int. 2010 Jan;21(1):189-93. Epub 2009 Apr 7. PMID: 19350338
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Clotting, Thrombosis
Problem Substances : Raloxifene
[+]

Supplemention of vitamin K antagonists with 100 mcg of vitamin K improves stability of anticoagulant therapy and reduces side effects. Oct 01, 2007

Pubmed Data : J Thromb Haemost. 2007 Oct;5(10):2043-8. Epub 2007 Jul 31. PMID: 17666020
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin K
Diseases : Clotting, Thrombosis
Additional Keywords : Drug-Plant-Vitamin Synergies, Vitamin K Myth
[+]

Topical wintergreen oil has anti-platelet activity equivalent to that of aspirin.May 01, 2002

Pubmed Data : Reprod Toxicol. 2002 May-Jun;16(3):237-43. PMID: 18698012
Article Published Date : May 01, 2002
Study Type : Human Study
Additional Links
Substances : Wintergreen
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-Platelet
Additional Keywords : Natural Substances Versus Drugs
[+]

Yoga significantly improves blood coagulation potentials. Apr 30, 1984

Pubmed Data : Thromb Haemost. 1984 Apr 30;51(2):196-7. PMID: 6740553
Article Published Date : Apr 30, 1984
Study Type : Human Study
Additional Links
Diseases : Clotting, Thrombosis
Therapeutic Actions : Yoga
Pharmacological Actions : Fibrinolytic Agents, Platelet Aggregation Inhibitors
[+]

Cocoa flavanol and procyanidin supplementation inhibits platelet function.Jun 01, 2003

Pubmed Data : Am J Clin Nutr. 2003 Jun;77(6):1466-73. PMID: 12791625
Article Published Date : Jun 01, 2003
Study Type : Animal Study
Additional Links
Substances : Catechin , Flavonoids
Diseases : Clotting
Pharmacological Actions : Platelet Aggregation Inhibitors
Additional Keywords : Proanthocyanidins
[+]

Ginkgo biloba extract enhances antiplatelet and antithrombotic effects of cilostazol without prolongation of bleeding time.Jan 01, 2005

Pubmed Data : Nutr Cancer. 2005;51(1):52-8. PMID: 19349067
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-thrombotic, Platelet Aggregation Inhibitors
Additional Keywords : Drug-Plant-Vitamin Synergies, Plant Extracts
[+]

Parsley extract inhibits platelet aggregation and prolongs bleeding time in rats.May 23, 2009

Pubmed Data : J Ethnopharmacol. 2009 May 23. PMID: 19467310
Article Published Date : May 23, 2009
Study Type : Animal Study
Additional Links
Substances : Parsley
Diseases : Clotting
Pharmacological Actions : Anti-Platelet
[+]

Sesamol has anti-platelet properties.Dec 01, 2010

Pubmed Data : J Nutr Biochem. 2010 Dec ;21(12):1214-21. Epub 2009 Dec 16. PMID: 20015631
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Clotting
Pharmacological Actions : Antioxidants, Platelet Aggregation Inhibitors
[+]

A carrot extract demonstrates antiplatelet and thrombolytic activity. Dec 01, 2008

Pubmed Data : Blood Coagul Fibrinolysis. 2008 Dec;19(8):785-92. PMID: 19002045
Article Published Date : Dec 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Carrot
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-Platelet, Thrombolytic
[+]

Apigenin inhibits platelet adhesion and thrombus formation and synergizes with aspirin in the suppression of the arachidonic acid pathway.May 14, 2008

Pubmed Data : J Agric Food Chem. 2008 May 14;56(9):2970-6. Epub 2008 Apr 15. PMID: 18410117
Article Published Date : May 14, 2008
Study Type : In Vitro Study
Additional Links
Substances : Apigenin
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-thrombotic, Platelet Aggregation Inhibitors
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Cinnamic aldehyde, a compound found within cinnnamon, exhibits anti-platelet properties. Apr 30, 1987

Pubmed Data : J Pharmacobiodyn. 1987 May ;10(5):201-8. PMID: 3040960
Article Published Date : Apr 30, 1987
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon
Diseases : Clotting
Pharmacological Actions : Anti-Platelet
[+]

Fennel essential oil demonstrates broad spectrum antiplatelet, antithrombotic, clot destabilizing, and vasorelaxant activity.Sep 01, 2007

Pubmed Data : Pharmacol Res. 2007 Sep;56(3):254-60. Epub 2007 Jul 14. PMID: 17709257
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Fennel
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-Platelet
[+]

Fucoidans possess antithrombotic and antiplatelet activities. May 31, 2012

Pubmed Data : Thromb Res. 2012 Jun ;129(6):771-8. Epub 2011 Aug 26. PMID: 21872298
Article Published Date : May 31, 2012
Study Type : Review
Additional Links
Substances : Fucoidan
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-Platelet, Anti-thrombotic
[+]

Polyphenols from olive exhibit anti-platelet activity which is associated with the cardiovascular benefits of the Mediterranean diet. Feb 01, 2008

Pubmed Data : Nutr Metab Cardiovasc Dis. 2008 Feb;18(2):127-32. Epub 2007 Mar 7. PMID: 17346951
Article Published Date : Feb 01, 2008
Study Type : Commentary
Additional Links
Substances : Flavonoids, Oleuropein, Olive leaf extract, Polyphenols
Diseases : Cardiovascular Diseases, Clotting, Thrombosis
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Anti-Platelet, Antioxidants
Additional Keywords : Plant Extracts
[+]

Resveratrol has anti-platelet activating activity. Jan 01, 2011

Pubmed Data : Am J Chin Med. 2011;39(1):145-59. PMID: 21213405
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Clotting
Pharmacological Actions : Anti-Platelet, Thromboxane (TXB) Inhibitors
[+]

Resveratrol induces platelet apoptosis, as well as inhibition of platelet aggregation. Aug 01, 2009

Pubmed Data : Cardiovasc Res. 2009 Aug 1;83(3):575-85. Epub 2009 May 7. PMID: 19423619
Article Published Date : Aug 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Clotting, Thrombocytopathy, Thrombocytosis, Thrombosis
Pharmacological Actions : Anti-Platelet
Additional Keywords : Platelet Apoptosis, Thrombocytosis
[+]

Shiitake exhibits anti-platelet activity. Jan 01, 2004

Pubmed Data : Biofactors. 2004;22(1-4):177-9. PMID: 15630278
Article Published Date : Jan 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Shiitake Mushroom
Diseases : Clotting
Pharmacological Actions : Platelet Aggregation Inhibitors
Additional Keywords : Plant Extracts
[+]

Tarragon (Artemisia d.) has anti-platelet, anticoagulant activity.Nov 01, 2007

Pubmed Data : J Ethnopharmacol. 2007 Nov 1;114(2):194-8. Epub 2007 Aug 2. PMID: 17855029
Article Published Date : Nov 01, 2007
Study Type : In Vitro Study
Additional Links
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-Platelet, Anticoagulants
Additional Keywords : Plant Extracts
[+]

Tarragon, savory and marjoram have anti-coagulant activity, confirming their traditional role in Iranian folk medicine for cardiovascular and thrombotic disorders.Apr 01, 2007

Pubmed Data : Biochim Biophys Acta. 2007 Apr;1770(4):578-84. Epub 2006 Dec 5. PMID: 18069068
Article Published Date : Apr 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Marjoram, Savory, Tarragon
Diseases : Cardiovascular Diseases, Clotting, Thrombosis
Pharmacological Actions : Platelet Aggregation Inhibitors
Additional Keywords : Plant Extracts, Science Confirms Tradition
[+]

The cis- form of resveratrol is more potent than the trans- form in decreasing collagen-induced platelet aggregation.Jan 01, 1996

Pubmed Data : Drugs Exp Clin Res. 1996;22(2):61-3. PMID: 8998912
Article Published Date : Jan 01, 1996
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Resveratrol: Cis- Form, Stilbenes
Diseases : Clotting, Thrombosis
Pharmacological Actions : Platelet Aggregation Inhibitors
Additional Keywords : Cis- Versus Trans- Resveratrol
[+]

Wasabi inhibits human platelet aggregation. Jan 01, 2000

Pubmed Data : Biofactors. 2000;13(1-4):271-6. PMID: 11237193
Article Published Date : Jan 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Wasabi
Diseases : Clotting
[+]

Wheat germ agglutinin (WGA) and concanavalin A (Con A) stimulate platelet aggregation.Jun 01, 1998

Pubmed Data : Biochemistry (Mosc). 1998 Jun;63(6):710-8. PMID: 9668212
Article Published Date : Jun 01, 1998
Study Type : In Vitro Study
Additional Links
Diseases : Clotting
Problem Substances : Concanavalin A, Wheat Germ Agglutinin (WGA)
[+]

Yucca has an anti-platelet effect that is stronger than resveratrol.May 01, 2002

Pubmed Data : Platelets. 2002 May;13(3):167-73. PMID: 12180499
Article Published Date : May 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Yucca
Diseases : Clotting, Thrombosis
Pharmacological Actions : Anti-Platelet
Additional Keywords : Yucca Schidigera
[+]

Yucca inhibits free radical generation in blood platelets and may be beneficial in protecting against cardiovascular disease when hyperactivity of platelets is observed.Jul 01, 2003

Pubmed Data : Nutrition. 2003 Jul-Aug;19(7-8):633-40. PMID: 12831950
Article Published Date : Jul 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Yucca
Diseases : Cardiovascular Diseases, Clotting
Pharmacological Actions : Anti-Platelet
Additional Keywords : Yucca Schidigera

Copyright: mikrostoker / 123RF Stock Photo

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