Coenzyme Q10 Deficiency

Views 1177

Download the GMI DOC on this Topic

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research

3 Substances Researched for Coenzyme Q10 Deficiency

Name	AC	CK	Focus
Coenzyme Q10	2	20
Astaxanthin	1	2
Vitamin E	1	2

5 Problem Substances Researched for Coenzyme Q10 Deficiency

Name	AC	CK	Focus
Statin Drugs	7	54
Atorvastatin	5	43
Pravastatin	2	20
Simvastatin	3	15
Lovastatin	2	12

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
13 Abstracts with Coenzyme Q10 Deficiency Research

Filter by Study Type

Sort Abstracts

Limited to Members Only

By default, all articles on GreenMedInfo.com are sorted based on the content type which best reflects the data which most users are searching for. For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members only. If you are already a member, you can sign in by clicking here. If you do not currently have a user account, and would like to create one/become a member, click here to begin the singup process.

Currently Available Sorting Options

Article Published Date - Sort all displayed articles by their published date
Quick Summary Fieldsets - Sort alphabetically, rather than by Cumulative Knowledge
Cumulative Knowledge - Default sorting method. Allows you to sort descendingly

Free Sample of Member-Only Features

Although all 30,000+ articles on GreenMedInfo.com are made entirely free to view as an educational service to the public, we provide a powerful set of enhanced data comprehension and retrieval tools for subscribing members. Above you are viewing a free preview, limited to 10000 rows, of the membership feature called "Cumulative Knowledge" (learn more).

The Focus Article Feature is not enabled.

Upgrading to the Friend membership gives you access to unlimited rows of Cumulative Knowledge data.

To Participate

Click here to login
Click here to order a membership

[+]

Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke.Jun 01, 2004

Click here to read the entire abstract

Pubmed Data : Arch Neurol. 2004 Jun;61(6):889-92. PMID: 15210526

Article Published Date : Jun 01, 2004

Study Type : Human Study

Additional Links

Diseases : Cardiovascular Diseases, Coenzyme Q10 Deficiency, Statin-Induced Pathologies, Stroke

Problem Substances : Atorvastatin

[+]

Atorvastatin reduces serum coenzyme Q10 levels (reduced and oxidized forms) in patients with high cholesterol.Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : J Atheroscler Thromb. 2005;12(2):111-9. PMID: 15942122

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Diseases : Coenzyme Q10 Deficiency, High Cholesterol, Statin-Induced Pathologies

Problem Substances : Atorvastatin, Statin Drugs

[+]

Atorvastatin worsens left ventricular diastolic function, which is improved through coenzyme q10 supplementation. Nov 15, 2004

Click here to read the entire abstract

Pubmed Data : Am J Cardiol. 2004 Nov 15 ;94(10):1306-10. PMID: 15541254

Article Published Date : Nov 15, 2004

Study Type : Human Study

Additional Links

Substances : Coenzyme Q10

Diseases : Coenzyme Q10 Deficiency, Heart Failure, Hypertension, Statin-Induced Pathologies

Pharmacological Actions : Anticholesteremic Agents, Antioxidants

Problem Substances : Atorvastatin, Statin Drugs

Adverse Pharmacological Actions : Cardiotoxic

[+]

Coenzyme Q10 has a corrective effect on statin-induced lowering of plasma coenzyme Q10 levels.Dec 01, 2007

Click here to read the entire abstract

Pubmed Data : Atherosclerosis. 2007 Dec;195(2):e182-9. Epub 2007 Aug 6. PMID: 17681347

Article Published Date : Dec 01, 2007

Study Type : Human Study

Additional Links

Substances : Coenzyme Q10

Diseases : Coenzyme Q10 Deficiency, Statin-Induced Pathologies

[+]

Statin therapy can be associated with high blood lactate/ pyruvate ratio suggestive of mitochondrial dysfunction. Sep 01, 1996

Click here to read the entire abstract

Pubmed Data : Br J Clin Pharmacol. 1996 Sep ;42(3):333-7. PMID: 8877024

Article Published Date : Sep 01, 1996

Study Type : Human Study

Additional Links

Diseases : Blood Lactate/ Pyruvate Ratio: Elevated, Coenzyme Q10 Deficiency, Mitochondrial Dysfunction , Statin-Induced Pathologies

Pharmacological Actions : Enzyme Inhibitors

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Myotoxicity

[+]

Statins lower plasma and lymphocyte ubiquinol/ubiquinone (coQ10) levels. Jan 01, 2003

Click here to read the entire abstract

Pubmed Data : Biofactors. 2003;18(1-4):113-24. PMID: 14695926

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Diseases : Coenzyme Q10 Deficiency, Statin-Induced Pathologies

Problem Substances : Atorvastatin, Pravastatin , Simvastatin, Statin Drugs

[+]

There is a dose-related decrease of serum coenzyme Q10 during treatment with statin drugs. Jan 01, 1997

Click here to read the entire abstract

Pubmed Data : Mol Aspects Med. 1997 ;18 Suppl:S137-44. PMID: 9266515

Article Published Date : Jan 01, 1997

Study Type : Human Study

Additional Links

Diseases : Coenzyme Q10 Deficiency, Drug-Induced Nutrient Depletion: Statin Drugs, Statin-Induced Pathologies

Pharmacological Actions : Antioxidants

Problem Substances : Lovastatin, Pravastatin , Statin Drugs

[+]

Simvastatin-induced lactic acidosis has been reported.Oct 01, 2002

Click here to read the entire abstract

Pubmed Data : Clin Pharmacol Ther. 2002 Oct ;72(4):461-4. PMID: 12386648

Article Published Date : Oct 01, 2002

Study Type : Human: Case Report

Additional Links

Diseases : Coenzyme Q10 Deficiency, Lactic Acidosis, Mitochondrial Dysfunction

Problem Substances : Simvastatin, Statin Drugs

[+]

Statin precipitated lactic acidosis has been reported. Sep 01, 2004

Click here to read the entire abstract

Pubmed Data : J Clin Pathol. 2004 Sep ;57(9):989-90. PMID: 15333664

Article Published Date : Sep 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Coenzyme Q10 Deficiency, Drug-Induced Nutrient Depletion: Statin Drugs, Lactic Acidosis, Statin-Induced Pathologies

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Atorvastatin

[+]

Astaxanthin and vitamin E may increase the endogenous production of coenzyme q10. Oct 01, 2010

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2010 Oct;104(7):980-8. Epub 2010 Jun 14. PMID: 20540821

Article Published Date : Oct 01, 2010

Study Type : Animal Study

Additional Links

Substances : Astaxanthin, Vitamin E

Diseases : Coenzyme Q10 Deficiency

Pharmacological Actions : Antioxidants

[+]

Lovastatin causes depletion of coenzyme Q10 levels in the cardiac muslce and mitochondria of animals.Jul 06, 1994

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 1994 Jul 6 ;1200(2):100-8. PMID: 8031828

Article Published Date : Jul 06, 1994

Study Type : Animal Study

Additional Links

Diseases : Coenzyme Q10 Deficiency, Drug-Induced Nutrient Depletion: Statin Drugs, Heart Failure, Statin-Induced Pathologies

Problem Substances : Lovastatin

Adverse Pharmacological Actions : Cardiotoxic, Myotoxicity

[+]

Simvastatin worsens the myocardial mitochondrial respiration during ischemia probably due to depletion of coenzyme Q10. Sep 01, 1995

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 1995 Sep ;116(2):1894-8. PMID: 8528576

Article Published Date : Sep 01, 1995

Study Type : Animal Study

Additional Links

Diseases : Coenzyme Q10 Deficiency, Drug-Induced Nutrient Depletion: Statin Drugs, Mitochondrial Dysfunction , Myocardial Ischemia, Statin-Induced Pathologies

Pharmacological Actions : Enzyme Inhibitors

Problem Substances : Simvastatin

Adverse Pharmacological Actions : Cardiotoxic, Myotoxicity

[+]

Coenzyme Q10 deficiency may be one mechanism for statin-induced myopathies.Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Ochsner J. 2010 ;10(1):16-21. PMID: 21603349

Article Published Date : Jan 01, 2010

Study Type : Review

Additional Links

Diseases : Coenzyme Q10 Deficiency, Drug-Induced Nutrient Depletion: Statin Drugs, Myopathies, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Myotoxicity

Copyright: foxterrier2005 / 123RF Stock Photo

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version