Cognitive Decline/Dysfunction

Name	AC	CK
Ginkgo biloba	9	92
Vitamin D	9	64
Bacopa	15	53
Omega-3 Fatty Acids	7	53
Vitamin B-12	6	52
Blueberry	10	51
Folic Acid	5	50
DHA (Docosahexaenoic Acid)	6	34
Phosphatidylserine	4	32
Vegetables: All	3	31
EPA (Eicosapentaenoic Acid)	3	30
Lutein	3	30
Pycnogenol (Pine Bark)	3	30
Vitamin B-6	3	30
Vitamin C	7	30
Zeaxanthin	3	30
Astaxanthin	7	28
Green Tea	5	26
Probiotics	6	25
Flavonoids	4	24
Vitamin E	4	24
Nuts	3	21
Black Tea	2	20
Chocolate	2	20
Coffee	1	20
Curcumin	11	20
Fruit: All	1	20
Grape	6	20
Polyunsaturated Fatty Acids (PUFAs)	2	20
Valerian	2	20
Ashwagandha	5	18
Polyphenols	5	18
Resveratrol	5	18
Melatonin	4	16
Nigella sativa (aka Black Seed)	4	16
Ginsenosides	8	15
Magnesium	4	15
Frankincense	3	14
Olive Oil	3	14
Strawberry	3	14
Coconut Oil	2	13
Medium Chain Triglycerides	2	13
Almond	2	12
Berries: All	2	12
Holy Basil	2	12
Lavender	2	12
Lion's Mane (Hericium Erinaceus)	2	12
Pomegranate	2	12
Caffeine	2	11
Antioxidant formulas	1	10
Bergamot orange	1	10
Blue Honeysuckle	1	10
Chlorogenic Acid	1	10
Cholesterol	1	10
Cocoa	1	10
Coconut	1	10
Codonopsis pilosula	1	10
Cruciferous Vegetables	1	10
Fish Oil	1	10
Folate	1	10
Ginger	1	10
Green Leafy Vegetables	1	10
Kava Kava	1	10
Lemon Balm	1	10
Monounsaturated fatty acids	1	10
Multivitamin	1	10
Oats	1	10
Orange	1	10
Peanut	1	10
Rosemary	1	10
Sage	1	10
Sea Cucumber	1	10
Sesamin	1	10
Sulforaphane	5	10
Thiamine (B-1)	1	10
Ubiquinol	1	10
Vitamin E: alpha tocopherol	1	10
Wine	1	10
Nobiletin	5	9
Berberine	4	8
Delta-tetrahydrocannabinol (THC)	4	8
Huperzine	4	8
Ellagic Acid	3	6
Pterostilbene	3	6
Puerarin	3	6
Walnut	3	6
Citrus Peel	3	5
Coenzyme Q10	3	5
Lotus	3	5
Alpha-Lipoic Acid	2	4
Apples	2	4
Asiatic Acid	2	4
Capparis spinosa (caper)	2	4
Krill	2	4
Piperine	2	4
Quercetin	2	4
Sea buckthorn	2	4
Sesamol	2	4
Spinach	2	4
Sweet Potato: Purple	2	4
Caprylic Acid	1	3
Chrysin	2	3
Orange: Mandarin	2	3
Tangeretin	2	3
Theanine	2	3
Acai	1	2
Acetyl-l-carnitine	1	2
Anthocyanins	1	2
Apigenin	1	2
Astragaloside	1	2
Bamboo	1	2
Beta Sitosterol	1	2
Betulinic acid	1	2
Bifidobacterium Breve	1	2
Bifidobacterium Longum	1	2
Black Pepper	1	2
Blackberry	1	2
Boron	2	2
Broccoli Sprouts	1	2
Cannabidiol	1	2
Cannabis	1	2
Carob	1	2
Carrot	1	2
Carvacrol	1	2
Catechin	1	2
Chinese Skullcap	1	2
Crocetin	1	2
Cryptoxanthin	1	2
Curcuma Longa	1	2
Dill	1	2
Diosmin	1	2
EGCG (Epigallocatechin gallate)	1	2
False Black Pepper	1	2
Fig	1	2
Fucoxanthin	1	2
Garlic	1	2
Genistein	1	2
Gingerol	1	2
Ginseng	1	2
Ginseng (Korean)	1	2
Glycyrrhizin	1	2
Gotu Kola	1	2
Guarana	1	2
Hesperidin	1	2
Honokiol	1	2
Icariin	1	2
Kudzu	1	2
Lactobacillus probiotics	1	2
Lavender: Essential Oil	1	2
Lycopene	1	2
Mangiferin	1	2
Moringa oleifera	1	2
Myricetin	1	2
NAC (N-acetyl-L-cysteine)	1	2
Nettle	1	2
Nicotinamide adenine dinucleotide (NADH)	1	2
Noni	1	2
Perilla	1	2
Persimmon	1	2
Plum	1	2
Prickly Pear Cactus	1	2
Procyanidin B2	1	2
Pueraria mirifica	1	2
Purslane	1	2
Raisins	1	2
Rooibos	1	2
Royal Jelly	1	2
Rutin	1	2
Selenium	1	2
Spikenard	1	2
Spirulina	1	2
Syrian rue	1	2
Tanshinone IIA	1	2
Thymol	1	2
Turmeric: Fermented	1	2
Ume (Japanese apricot)	1	2
Vanillin	1	2
Water: Deep Sea	1	2
Water: Deuterium Depleted	1	2
Xanthohumol	1	2
2,3,5,4'-tetrahydroxystilbene-2-O-β -D-glucoside (THSG)	1	1
B-complex	1	1
Beet	1	1
Butyrate	1	1
Docosahexaenoic acid (DHA)	1	1
Fermented Foods and Beverages	1	1
Fiber	1	1
Luteolin	1	1
Prebiotics	1	1
Propolis: Brazillian	1	1
Rhodiola (Tibetan Ginseng)	1	1
Tart Cherry	1	1

Name	AC	CK
Fluoride	3	42
Tamoxifen	3	40
Statin Drugs	5	33
Simvastatin	4	24
Thimerosal	1	20
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	2	12
Lovastatin	2	11
Aluminum Hydroxide	1	10
Arimidex	1	10
Fructose	1	10
Pesticides	1	10
Polychlorinated biphenyls (PCBs)	1	10
Pravastatin	1	10
Raloxifene	1	10
Sucrose	1	10
Aluminum	3	6
Aluminum Chloride	2	4
Atorvastatin	2	3
Acrylamide	1	2
Antibiotics	1	2
Aspartame	1	2
Bisphenol A	1	2
Cyclophosphamide	1	2
Doxorubicin	1	2
Formaldehyde	1	2
Lead	1	2
Monosodium Glutamate (MSG)	1	2
Nicotine	1	2
Trans Fatty Acids	1	2
Alcohol Consumption	1	1
Cholesterol Lowering Drugs	1	1
Ethanol	1	1
High Fructose Corn Syrup	1	1

Name	AC	CK
Exercise	29	198
Exercise: Aerobic	5	51
Dietary Modification: Mediterranean Diet	5	41
Tai Chi	3	30
Acupuncture	3	22
Music	3	21
Meditation	2	20
Sunlight exposure	2	20
Laser Treatment: Low-Level	3	13
Integrative Medicine	2	11
Acupuncture: auricular	1	10
Aromatherapy	1	10
Chiropractic treatment	1	10
Dancing	1	10
Exercise: Cycling	1	10
Gum Chewing	1	10
Kundalini Yoga	1	10
Mantra	1	10
Mindfullness Training	1	10
Qigong	1	10
Shinrin-yoku (taking in the atmosphere of the forest)	1	10
Sunlight Exposure: UVB Light	1	10
Therapeutic Breathing	1	10
Yogic Breathing	1	10
Fasting/Caloric Restriction	3	6
Dietary Modification: Low Carbohydrate/Ketogenic	1	2
Electroacupuncture	1	2
Cognitive Behavioural Approaches	1	1
Drumming	1	1
Hyperbaric Treatment	1	1
Yoga	1	1

Name	AC	CK
Chemotherapy	2	12
Artifical Lighting	1	10
Vaccination: All	1	10
Vaccination: HPV (Gardasil)	1	10
Shift Work	1	2
Western Diet	1	1

Additional Keywords : Risk Reduction

[+]

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neurol India. 2016 Jan-Feb;64(1):56-61. PMID: 26754993

Article Published Date : Dec 31, 2015

Study Type : Meta Analysis, Review

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dementia, Inflammation, Rheumatoid Arthritis

Additional Keywords : Increased Risk

[+]

This meta-analysis suggests that physical activity interventions positively influence cognitive function in patients with dementia.Dec 31, 2015

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Pubmed Data : Ageing Res Rev. 2016 Jan ;25:13-23. Epub 2015 Nov 28. PMID: 26607411

Article Published Date : Dec 31, 2015

Study Type : Meta Analysis

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dementia

Therapeutic Actions : Exercise, Exercise: Aerobic

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Physical Activity, Risk Reduction

[+]

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2019 Nov 22:e1900532. Epub 2019 Nov 22. PMID: 31755209

Pubmed Data : J Alzheimers Dis. 2016 Apr 8. Epub 2016 Apr 8. PMID: 27079708

Article Published Date : Apr 07, 2016

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Therapeutic Actions : Meditation

[+]

Acupuncture at Tiaoshen Yizhi acupoints can be used to improve cognitive function in patients with mild cognitive impairment.Jan 31, 2017

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Pubmed Data : Neural Regen Res. 2017 Feb ;12(2):250-258. PMID: 28400807

Article Published Date : Jan 31, 2017

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Therapeutic Actions : Acupuncture

Pharmacological Actions : Neuroprotective Agents

[+]

Acute effects of a polyphenol-rich leaf extract of Mangifera indica on cognitive function in healthy adults.Jul 22, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Am Geriatr Soc. 2013 Feb ;61(2):177-84. PMID: 23405916

Article Published Date : Jan 31, 2013

Study Type : Human Study

Additional Links

Diseases : Aging, Cognitive Decline/Dysfunction, Periodontal Diseases

Additional Keywords : Diseases that are Linked

[+]

Aerobic fitness may have a positive influence on protection of brain even in aMCI CSF biomarker, a high-risk population to convert to AD.May 31, 2016

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Pubmed Data : Age (Dordr). 2016 Jun ;38(3):51. Epub 2016 Apr 23. PMID: 27106271

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Blueberry supplementation led to enhanced neural activation in mild cognitive impairment. Feb 20, 2017

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Pubmed Data : Nutr Neurosci. 2017 Feb 21:1-9. Epub 2017 Feb 21. PMID: 28221821

Article Published Date : Feb 20, 2017

Study Type : Human Study

Additional Links

Substances : Blueberry

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Both Ayurveda Rasayana and integrated yoga intervention found to be effective in improving cognitive abilities.Dec 17, 2020

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Pubmed Data : J Ayurveda Integr Med. 2020 Dec 18. Epub 2020 Dec 18. PMID: 33349568

Article Published Date : Dec 17, 2020

Continuous intake of chlorogenic acids appears to improve attention and executive function among cognitive functions in mild cognitive impairment.Oct 28, 2019

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Pubmed Data : J Alzheimers Dis. 2019 Oct 29. Epub 2019 Oct 29. PMID: 31683483

Article Published Date : Oct 28, 2019

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Cycling in appears to improve some aspects of cognitive function and mental health.Dec 31, 2018

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Pubmed Data : PLoS One. 2019 ;14(2):e0211779. Epub 2019 Feb 20. PMID: 30785893

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Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2020 Nov 20 ;38(11):831-834. PMID: 33287476

Article Published Date : Nov 19, 2020

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Herbicide Toxicity

Problem Substances : Paraquat

Adverse Pharmacological Actions : Neurotoxic

[+]

Effects of matcha green tea powder on cognitive functions of community-dwelling elderly individuals.Nov 25, 2020

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Pubmed Data : Nutrients. 2020 Nov 26 ;12(12). Epub 2020 Nov 26. PMID: 33256220

Article Published Date : Nov 25, 2020

Study Type : Human Study

Additional Links

Substances : Green Tea

Diseases : Aging: Brain , Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Electrohypersensitive persons in this study were suffering not only from their symptoms, but also from economical and social problems.Apr 01, 2012

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Pubmed Data : Pathophysiology. 2012 Apr ;19(2):95-100. Epub 2012 Mar 27. PMID: 22458999

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Pubmed Data : Nutrients. 2019 Nov 26 ;11(12). Epub 2019 Nov 26. PMID: 31779179

Article Published Date : Nov 25, 2019

Study Type : Human Study

Additional Links

Substances : Vitamin D, Yoghurt

Diseases : Aging: Brain , Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

G. biloba seemed to slow down the cognitive deterioration in patients with vascular cognitive impairment.Dec 31, 2016

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Pubmed Data : Nutr Neurosci. 2020 Jan 16:1-10. Epub 2020 Jan 16. PMID: 31942838

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Pubmed Data : Electromagn Biol Med. 2015 Sep ;34(3):262-4. PMID: 26444203

Article Published Date : Sep 01, 2015

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dizziness, Fatigue, Headache, Sleep Disorders

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

[+]

Click here to read the entire abstract

Pubmed Data : Neurobiol Aging. 2006 Nov;27(11):1694-704. Epub 2005 Oct 26. PMID: 16256248

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Monounsaturated fatty acids, Polyunsaturated Fatty Acids (PUFAs)

Diseases : Cognitive Decline/Dysfunction

Therapeutic Actions : Dietary Modification: Mediterranean Diet

[+]

Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults.Jun 30, 2012

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Pubmed Data : Ann Neurol. 2012 Jul ;72(1):135-43. Epub 2012 Apr 26. PMID: 22535616

Article Published Date : Jun 30, 2012

Study Type : Human Study

Additional Links

Substances : Berries: All, Blueberry, Flavonoids, Strawberry

Diseases : Aging, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

Higher intake of polyunsaturated fatty acids (PUFA) and fish oil was associated with better semantic memory and global cognitive function. Jul 01, 2008

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Pubmed Data : Int J Geriatr Psychiatry. 2008 Jul;23(7):741-7. PMID: 18188871

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Substances : Polyunsaturated Fatty Acids (PUFAs)

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

[+]

Higher levels of cardiorespiratory fitness are associated with better white matter fiber integrity.Dec 31, 2017

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Pubmed Data : J Alzheimers Dis. 2018 ;61(2):729-739. PMID: 29226864

Article Published Date : Dec 31, 2017

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Pubmed Data : Br J Nutr. 2011 Jun 1:1-10. Epub 2011 Jun 1. PMID: 21736803

Article Published Date : Jun 01, 2011

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Intelligence Quotient (IQ): Low/Impaired, Learning disorders

Problem Substances : Fructose, Sucrose

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Alzheimers Dis. 2016 Mar 11. Epub 2016 Mar 11. PMID: 26967227

Article Published Date : Mar 10, 2016

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Dementia, Sitting Sickness

Therapeutic Actions : Exercise

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Factors, Risk Reduction

[+]

Inflammation and altered endothelial function may play roles in domain-specific cognitive decline of non-demented individuals.Aug 12, 2016

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Pubmed Data : J Gerontol A Biol Sci Med Sci. 2016 Aug 13. Epub 2016 Aug 13. PMID: 27522059

Article Published Date : Aug 12, 2016

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Inflammation

[+]

Inflammation is particularly detrimental in inactive older adults and may exacerbate the negative effects of physical inactivity on brain.May 08, 2016

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Pubmed Data : Hum Brain Mapp. 2016 May 9. Epub 2016 May 9. PMID: 27159568

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Pubmed Data : J Inorg Biochem. 2009 Nov ;103(11):1571-8. Epub 2009 Aug 20. PMID: 19748679

Article Published Date : Oct 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cureus. 2020 Feb 13 ;12(2):e6976. Epub 2020 Feb 13. PMID: 32206454

Article Published Date : Feb 12, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin B-12

Diseases : Cognitive Decline/Dysfunction, Dementia, Vitamin B 12 Deficiency

Pharmacological Actions : Neuroprotective Agents

[+]

Low vitamin D level was associated with greater risk of cognitive impairment in older as well as younger adults.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Alzheimers Dis. 2017 ;56(3):899-916. PMID: 28106552

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Therapeutic Actions : Meditation , Music

[+]

Mediterranean diet and risk for dementia and cognitive decline in a Mediterranean population.Mar 15, 2021

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Pubmed Data : J Am Geriatr Soc. 2021 Mar 16. Epub 2021 Mar 16. PMID: 33724444

Article Published Date : Mar 15, 2021

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Pubmed Data : J Neurophysiol. 2015 Apr 1 ;113(7):2753-9. Epub 2015 Feb 18. PMID: 25695646

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Pubmed Data : Bioelectromagnetics. 2009 Dec ;30(8):678-86. PMID: 19644978

Article Published Date : Dec 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation, Wi-Fi Radiation

Problem Substances : Cell Phone Exposure

[+]

Moderate intensity of aerobic exercise can improve cognitive function in patients with mild Alzheimer's disease.Dec 31, 2014

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Pubmed Data : CNS Neurol Disord Drug Targets. 2015 ;14(10):1292-7. PMID: 26556080

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Therapeutic Actions : Exercise: Aerobic, Exercise: Cycling

[+]

Multi-nutrient supplementation improved cognition and mobility in able older females at clinically relevant levels.Jan 31, 2016

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Pubmed Data : J Gerontol A Biol Sci Med Sci. 2016 Feb ;71(2):236-42. Epub 2015 Aug 11. PMID: 26265727

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Pubmed Data : Neuroimage. 2016 May 1 ;131:226-38. Epub 2015 Oct 1. PMID: 26433119

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Pubmed Data : Brain. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31746986

Article Published Date : Nov 19, 2019

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Alzheimer's Disease, Cognitive Decline/Dysfunction

[+]

People with the heaviest opioid or NSAID use had slightly higher dementia risk than people with little or no use.Jul 31, 2015

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Pubmed Data : J Am Geriatr Soc. 2015 Aug ;63(8):1519-26. PMID: 26289681

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dementia

Additional Keywords : Risk Factors

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Periodontitis was associated with an increase in cognitive decline in Alzheimer’s Disease.Dec 31, 2015

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Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints.Dec 31, 2012

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Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:946298. Epub 2013 Jul 22. PMID: 23970941

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Pubmed Data : J Neurosurg Sci. 2015 Dec ;59(4):437-46. PMID: 26635191

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Neurosci. 2018 Feb 21:1-7. Epub 2018 Feb 21. PMID: 29384421

Article Published Date : Feb 20, 2018

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis

Additional Keywords : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis, Risk Factors

[+]

Serum Vitamin D deficiency was associated with mild cognitive impairment and dementia.Dec 31, 2018

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Pubmed Data : Rev Invest Clin. 2019 ;71(6):381-386. PMID: 31823966

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Dementia, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Short term electromagnetic field exposure may not have an effect on mood, cognitive function, sleep, or overall wellbeing.Jul 01, 2015

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Pubmed Data : Environ Res. 2015 Jul ;140:85-94. Epub 2015 Mar 31. PMID: 25839715

[+]

Superior effects of modified Chen-Style Tai Chi versus 24-style Tai Chi on cognitive function, fitness, and balance performance in adults over 55.May 03, 2019

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Pubmed Data : Neurorehabil Neural Repair. 2018 Feb ;32(2):142-149. Epub 2018 Jan 20. PMID: 29353543

Article Published Date : Jan 31, 2018

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Therapeutic Actions : Tai Chi

Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents

[+]

Tai chi qigong can be considered a useful non-pharmacological approach for improving sleep quality in older adults with cognitive impairment.Dec 31, 2015

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[+]

The results of this study indicate that working in an occupation with high or medium-high magnetic field exposure may increase the risk of severe cognitive dysfunction.Apr 16, 2014

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Pubmed Data : Am J Epidemiol. 2017 Jul 13. Epub 2017 Jul 13. PMID: 28992036

Article Published Date : Jul 12, 2017

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Sitting Sickness

[+]

These results indicate that working near a 1.5 Tesla MRI system may elicit neurobehavioral effects. Oct 01, 2003

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Pubmed Data : Magn Reson Med. 2003 Oct ;50(4):670-4. PMID: 14523950

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Pubmed Data : Nutrients. 2018 Sep 20 ;10(10). Epub 2018 Sep 20. PMID: 30241302

Article Published Date : Sep 19, 2018

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

This cohort study demonstrates a potential adverse effect of microwave radiofrequency electromagnetic fields on cognitive function that involve brain regions mostly exposed during mobile phone use.Jan 01, 2018

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Pubmed Data : Eur J Nutr. 2019 Jun 21. Epub 2019 Jun 21. PMID: 31227861

Article Published Date : Jun 20, 2019

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Pubmed Data : Wei Sheng Yan Jiu. 2000 Mar 30 ;29(2):102-3. PMID: 12725088

Article Published Date : Mar 30, 2000

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Additional Keywords : EMF

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation

Problem Substances : Cell Phone Exposure

[+]

Using a phone more than 2 hours a day is associated with sleep deprivaiton and day sleepiness in medical students.Jan 01, 2014

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Pubmed Data : Nutr Neurosci. 2020 Aug 13:1-11. Epub 2020 Aug 13. PMID: 32787648

Article Published Date : Aug 12, 2020

Study Type : Animal Study

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Substances : Hibiscus sabdariffa

Diseases : Cognitive Decline/Dysfunction, Ovarian Diseases

Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents

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Pubmed Data : Biochimie. 2016 Aug 26. Epub 2016 Aug 26. PMID: 27569259

Article Published Date : Aug 25, 2016

Study Type : Animal Study

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Substances : Omega-3 Fatty Acids, Vitamin B-12

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

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A diet containing a mixture of P. montana and red ginseng extracts reversed learning and memory impairments.Jul 31, 2018

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Pubmed Data : Food Sci Biotechnol. 2018 Aug ;27(4):1193-1200. Epub 2018 Apr 4. PMID: 30263850

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Pubmed Data : Neurotox Res. 2017 Sep 21. Epub 2017 Sep 21. PMID: 28933048

Article Published Date : Sep 20, 2017

Study Type : Animal Study

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Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neurogenesis

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Aged garlic ethyl acetate extract may therefore be a beneficial food for protecting against neurodegeneration such as Alzheimer's disease.May 31, 2019

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Pubmed Data : Prev Nutr Food Sci. 2019 Jun ;24(2):165-170. Epub 2019 Jun 30. PMID: 31328121

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Pubmed Data : Mar Drugs. 2019 Jan 3 ;17(1). Epub 2019 Jan 3. PMID: 30609815

Article Published Date : Jan 02, 2019

Study Type : Animal Study

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Substances : Astaxanthin

Diseases : Cognitive Decline/Dysfunction, Tobacco Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Glutathione Upregulation , Interleukin-6 Downregulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Astaxanthin improves aluminum-induced impaired memory performances.Apr 14, 2016

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Pubmed Data : Eur J Pharmacol. 2016 Apr 15 ;777:60-9. Epub 2016 Feb 27. PMID: 26927754

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Pubmed Data : Sci Rep. 2017 Oct 18 ;7(1):13510. Epub 2017 Oct 18. PMID: 29044140

Article Published Date : Oct 17, 2017

Study Type : Animal Study

Additional Links

Substances : Bifidobacterium Breve

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

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Bacopa enhances cognitive function and protects against neurodegeneration in an Alzheimer's disease model. Oct 04, 2009

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Pubmed Data : J Ethnopharmacol. 2009 Oct 4. Epub 2009 Oct 4. PMID: 19808086

Article Published Date : Oct 04, 2009

Study Type : Animal Study

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Substances : Bacopa

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Neurodegenerative Diseases

[+]

Additional Keywords : Plant Extracts

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Behavioural domains and the gut microbiome are both impacted by diet and exercise but in unrelated ways.Dec 31, 2013

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Pubmed Data : J Appl Toxicol. 2021 Jan 20. Epub 2021 Jan 20. PMID: 33474794

Article Published Date : Jan 19, 2021

Study Type : Animal Study

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Diseases : Asthma, Bisphenol Toxicity, Cognitive Decline/Dysfunction

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Neurotoxic

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View the Evidence: 651 Abstracts with Cognitive Decline/Dysfunction Research

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Bacopa monnieri has the potential to improve cognition.Dec 31, 2013

Children who live in a fluorosis area have 5 times higher odds of developing low IQ than those who live in a nonfluorosis area or a slight fluorosis area.Jan 01, 2008

Exposure to high levels of fluoride may adversely influence children's intelligence development.Dec 01, 2008

Higher coffee consumption is associated with reduced risk for Alzheimer disease.May 31, 2016

Increased consumption of fruit and vegetables is associated with a reduced risk of cognitive impairment and dementia.Dec 31, 2016

Meta-analysis of controlled trials testing horticultural therapy for the improvement of cognitive function.Sep 02, 2020

Meta-analytic findings suggested overall benefits of EGb 761 for stabilizing or slowing decline in cognition of subjects with cognitive impairment and dementia.Dec 31, 2014

People with various levels of cognitive impairment can benefit from supervised multi-modal exercise.Dec 26, 2017

Rates of autism, speech disorders, mental retardation, infantile spasms, and thinking abnormalities were higher in children exposured to higher thimerosal levels.Aug 01, 2006

Tamoxifen interferes with cognitive function in breast cancer patients. Nov 01, 2000

This meta-analysis found a statistically significant increase in the risk of dementia among patients with rheumatoid arthritis.Dec 31, 2015

This meta-analysis suggests that physical activity interventions positively influence cognitive function in patients with dementia.Dec 31, 2015

This study suggests that meditation and mind-body exercises are effective to improve cognition of older adults aged 60 years or above.Feb 22, 2019

Yoga-related mind-body interventions for older adults appear to be safe, feasible, and effective alternative practice for maintenance of cognitive functions.Dec 06, 2020

"Effects of prior light exposure on early evening performance, subjective sleepiness, and hormonal secretion."Feb 01, 2012

8 weeks of qigong training increased aerobic capacity and tended to improve working memory in otherwise sedentary young females.Feb 19, 2021

A 5-min bout of walking at a self-selected intensity is associated with improved cognitive function.Jan 04, 2018

A closer adherence to the Mediterranean diet was associated with a better cognitive status.Apr 04, 2018

A greater intake of choline and lutein and zeaxanthin was associated with faster performance on a cognitive flexibility task in overweight people.Jan 14, 2021

A high intake of nuts may protect older adults from cognitive decline.Nov 21, 2019

A higher consumption of green tea is associated with a lower prevalence of cognitive impairment in humans.Feb 01, 2006

A lack of attention and concentration may occur in subjects who talk on mobile phones for longer times, compared to those who use phones relatively less.Sep 30, 2017

A Mediterranean diet supplemented with olive oil or nuts is associated with improved cognitive function in older populations. Jun 30, 2015

A moderate intake of EPA and DHA may postpone cognitive decline in elderly men. Apr 01, 2007

A polyphenol-rich extract from grape and blueberry improves age-related episodic memory decline in individuals with the highest cognitive impairments.Jul 18, 2018

A robust association was found between low omega-3 levels and cognitive impairment in an elderly population. Oct 04, 2016

A sedentary lifestyle could be a potential risk factor for mild cognitive impairment or subsequent dementia.Apr 24, 2018

A simple meditation or music listening program may improve stress, mood, well-being, sleep, and QOL in adults with subjective cognitive decline.Apr 07, 2016

Acupuncture at Tiaoshen Yizhi acupoints can be used to improve cognitive function in patients with mild cognitive impairment.Jan 31, 2017

Acute effects of a polyphenol-rich leaf extract of Mangifera indica on cognitive function in healthy adults.Jul 22, 2020

Acute low-level exposure to microwaves modulated at 7 Hz can affect cognitive processes such as attention and short-term memory in humans.Oct 01, 2002

Adherence to Mediterranean diet and subsequent cognitive decline in men with cardiovascular disease.Jan 21, 2020

Adverse oral health and cognitive decline: the health, aging and body composition study.Jan 31, 2013

Aerobic fitness may have a positive influence on protection of brain even in aMCI CSF biomarker, a high-risk population to convert to AD.May 31, 2016

Almond consumption leads to an improvement in cognitive function in overweight and obese patients. Jan 31, 2017

Anticholinergic burden and risk of cognitive impairment in elderly nursing home residents with depression.May 27, 2019

Aronia melanocarpa extract showed beneficial effects on cognitive performance and blood pressure in individuals at risk of cognitive decline.Aug 16, 2020

Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder.Nov 08, 2018

Ashwagandha may be effective in enhancing both immediate and general memory in people with mild cognitive impairment.Nov 01, 2017

Assessment of cognitive impairment and its correlation with vitamin D levels patients on maintenance hemodialysis.Feb 29, 2020

Association of vitamin D and vitamin B12 with cognitive impairment in elderly aged 80 years or older.Feb 27, 2019

Astaxanthin-rich Haematococcus pluvialis extract improves cognitive function in the healthy aged individuals.Aug 31, 2012

B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.Jul 21, 2011

Bacopa enhances cognitive performance in the aging.Jul 01, 2008

Being physically active during early adulthood and midlife contributes to prevention of poor subjective cognitive function in late-life.Nov 16, 2017

Bergamot polyphenolic fraction administration may be proposed as a potential supplementation strategy to improve cognitive outcome in schizophrenia.Jul 31, 2017

Black tea consumption was association with better cognitive performance among the elderly aged 60 years and above in China.Dec 31, 2014

Blueberry supplementation led to enhanced neural activation in mild cognitive impairment. Feb 20, 2017

Both Ayurveda Rasayana and integrated yoga intervention found to be effective in improving cognitive abilities.Dec 17, 2020

Breath Qigong improves recognition in seniors With vascular cognitive impairment.Dec 31, 2018

Caffeine intake was related to moderately better cognitive maintenance over 5 years in older women with vascular disorders.Dec 31, 2012

Chocolate intake is associated with better cognitive function.Apr 30, 2016

Chocolate intake was associated with a lower risk of cognitive decline.May 05, 2016

Chronic daily consumption of flavanone-rich 100% orange juice over 8 week was beneficial for cognitive function in healthy older adults.Feb 28, 2015

Chronic hyperglycemia in people with diabetes may disrupt the brain’s topological integration, and lead to mental slowing and cognitive impairment.Dec 31, 2015

Circulating levels of autophagy markers were low in children with higher fluoride body burden and lower intelligence quotient scores.Aug 31, 2019

Circulating vitamin D levels and Alzheimer's disease.Dec 01, 2019

Cognitive deterioration among bipolar disorder patients infected by Toxoplasma gondii is correlated to interleukin 6 levels.Jun 30, 2015

Cognitive function improvement with astaxanthin and tocotrienol intake.Oct 31, 2020

Cognitive improvement and safety assessment of a dietary supplement containing propolis extract in elderly Japanese.Dec 31, 2020

Continuous intake of chlorogenic acids appears to improve attention and executive function among cognitive functions in mild cognitive impairment.Oct 28, 2019

Cycling in appears to improve some aspects of cognitive function and mental health.Dec 31, 2018

Dance therapy improves cognitive functioning, quality of life and psychological well-being in elderly persons.Jan 01, 2010

Dangshen (Codonopsis pilosula) and Bai guo (Gingko biloba) enhance learning and memory. Jul 01, 2004

Decreased sunlight exposure is associated with an increased probability of cognitive impairment among depressed individuals. Aug 01, 2009

Delayed manifestation of cognitive dysfunction post-HPV vaccination.Jun 30, 2015

Dewaxed brown rice has the potential to be a useful staple food that maintains brain homeostasis among elderly individuals.Dec 31, 2018

Dietary intake of riboflavin and unsaturated fatty acid can improve the multi-domain cognitive function in middle-aged and elderly populations.Dec 31, 2018

Dietary niacin may protect against Alzheimer's disease and age related cognitive decline.Jul 31, 2004

Dietary supplementation with blueberries improves cognition among older adults.Mar 09, 2017

Effects of 12-week avocado consumption on cognitive function among adults with overweight and obesity.Jan 31, 2020

Effects of acute paraquat poisoning on cognitive ability in humans.Nov 19, 2020

Cognitive Decline/Dysfunction

View the Evidence:
651 Abstracts with Cognitive Decline/Dysfunction Research