Cold and Flu

Name	AC	CK
Echinacea	23	202
Vitamin D	20	128
Vitamin C	27	108
Probiotics	13	101
Fermented Foods and Beverages	5	91
Beta-glucan	4	82
Green Tea	11	76
Yeast	3	76
Elderberry	13	72
Ginseng (American)	3	62
Catechin	8	57
Homeopathic Medicine: All	7	53
Andrographis	6	45
Bifidobacterium Bifidum	3	42
Zinc	12	42
Pelargonium sidoides	4	33
Black Tea	4	32
Flavonoids	13	26
Yoghurt	4	25
Cinnamon	3	23
Bee Propolis	3	22
Lactoferrin	10	21
Apricot Kernel	1	20
Bifidobacterium	2	20
Broccoli Sprouts	2	20
Ephedra sinica (Ma Huang)	1	20
NAC (N-acetyl-L-cysteine)	13	18
Curcumin	11	16
Lactobacillus paracasei	4	16
Polyphenols	6	16
Lactobacillus rhamnosus GG	3	14
Beet	2	12
Bifidobacterium Longum	2	12
Lactobacillus delbrueckii Subsp	2	12
Lactobacillus gasseri	2	12
Lactobacillus plantarum	2	12
Lysine	2	11
Tea	2	11
Boehmeria jamaicensis	1	10
Cocoa	1	10
FOS (Fructooligosaccharides)	1	10
Fruit: All	1	10
Garlic: Aged	1	10
Germanium	1	10
Homeopathic Medicine: Oscillococcinum	1	10
Japanese Herbal Formula: Mao-to	1	10
Lactobacilius bulgaricus	1	10
Lactobacillus Acidophilus	1	10
Lactobacillus Brevis	1	10
Menthol	1	10
Modified Rice Bran (MGN-3)	1	10
Multivitamin	1	10
Pycnogenol (Pine Bark)	1	10
Rice Bran	1	10
Theanine	1	10
Thujae occidentalis	1	10
Vegetables: All	1	10
Wild Indigo	1	10
EGCG (Epigallocatechin gallate)	6	9
Berberine	5	8
Licorice	5	7
Medicinal Mushrooms	6	7
Quercetin	7	7
Selenium	6	7
Ginger	3	6
Ginseng (Korean)	4	6
Black Currant	4	5
Cranberry	4	5
Garlic	4	5
Ginseng	3	5
Ginsenosides	3	5
Kaempferol	3	5
Onion	3	5
Patchouli	5	5
Pomegranate	4	5
Turmeric	4	5
Vitamin A	3	5
Andrographolide	3	4
Bifidobacterium animalis	2	4
Black Raspberry Seed	1	4
Blueberry	3	4
Chinese Skullcap	3	4
Clinacanthus siamensis	1	4
Emodin	3	4
Eucalyptus	3	4
Gallic Acid	1	4
Ginkgo biloba	3	4
Guava	3	4
Hesperidin	2	4
Honeysuckle	4	4
Lactobacillus rhamnosus	2	4
Rosemaric Acid	2	4
Tetrahydrocurcumin	3	4
Watermelon	3	4
Aloe Vera	3	3
Astragalus	2	3
Bee Venom	2	3
Bilberry	2	3
Chokeberry	3	3
Chrysin	3	3
Cordyceps sinensis	2	3
Goji	2	3
Honey	1	3
Honeydew (melon)	1	3
Lemon Balm	3	3
Lychee	2	3
Manuka Honey	1	3
Mosla scabra	2	3
Oligonol	2	3
Olive leaf extract	2	3
Salvia miltiorrhiza	2	3
Spirulina	2	3
Syrian rue	2	3
Thymoquinone	2	3
Vitamin E	2	3
AHCC	1	2
Algae	1	2
Apigenin	2	2
Bamboo	2	2
Banaba	2	2
Betulinic acid	1	2
Bisdemethoxycurcumin	1	2
Caffeine	1	2
Carnosic Acid	1	2
Carvacrol	1	2
Coenzyme Q10	2	2
DHEA (Dehydroepiandrosterone)	1	2
Demethoxycurcumin	1	2
Dihydrocurcumin	1	2
False Black Pepper	1	2
Fiber	1	2
Fruit Peel	1	2
Garcinia kola	1	2
Glycyrrhizin	2	2
Hibiscus	2	2
Holy Basil	2	2
Horseradish	1	2
Indigo Naturalis	1	2
Isoliquiritigenin	1	2
Isoquercitrin	1	2
Japanese Herbal Formula: Sho-seiryu-to	1	2
Lactobacillus probiotics	1	2
Magnesium	2	2
Melatonin	1	2
Mushrooms: All	2	2
Myrrh	2	2
Neem	2	2
Omega-3 Fatty Acids	2	2
Organosulfur Compounds	1	2
Paeoniflorin	1	2
Panax Notoginseng	1	2
Persimmon	2	2
Radix Isatidis	1	2
Raspberry	2	2
Resveratrol	2	2
Rhodiola (Tibetan Ginseng)	1	2
Saffron	2	2
Sappanwood	1	2
Shiitake Mushroom	1	2
Sophora Flavescens	1	2
St. Johns Wort	1	2
Star Anise (Illicium anisatum)	2	2
Sulforaphane	1	2
Ume (Japanese apricot)	2	2
White Mulberry	2	2
Adlay	1	1
Agrimony	1	1
Anise	1	1
Anthocyanins	1	1
Apple Pectin	1	1
Artesunate	1	1
Ashwagandha	1	1
Astragaloside	1	1
Babchi	1	1
Bacillus subtilis	1	1
Bael	1	1
Bai Zhu	1	1
Bee Pollen	1	1
Beta Sitosterol	1	1
Black Pepper	1	1
Blackberry	1	1
Boneset	1	1
Bromelain	1	1
Cannabinoids	1	1
Carrot	1	1
Cashew	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chlorogenic Acid	1	1
Chrysanthemum Indicum	1	1
Citrus Pectin	1	1
Copper	1	1
Curcuminoids	1	1
Dandelion	1	1
Eleutherococcus senticosus	1	1
Ellagic Acid	1	1
Euphorbium resinifera	1	1
Fennel	1	1
Flaxseed	1	1
Folate	1	1
Frankincense	1	1
Fructans	1	1
Fucoidan	1	1
Ginseng (Siberian)	1	1
Glutathione	1	1
Griffithsin	1	1
Guduchi	1	1
Gum arabic	1	1
Gynostemma	1	1
Hops	1	1
Hu Zhang (Polygonum cuspidatum)	1	1
Hydrogen Peroxide	1	1
Iron	1	1
Kaempferia parviflora	1	1
Lactobacillus casei	1	1
Lingonberry	1	1
Lotus	1	1
Luteolin	1	1
Magnolol	1	1
Maitake Mushroom	1	1
Marigold	1	1
Moringa oleifera	1	1
Mugwort	1	1
Mulberry	1	1
Mullein	1	1
Myrica rubra	1	1
Naringenin	1	1
Nordihydroguaiaretic acid (NDGA)	1	1
Olive	1	1
Oregano	1	1
Palmitoylethanolamide	1	1
Papain	1	1
Peanut	1	1
Peony	1	1
Peppermint	1	1
Phellinus Linteus	1	1
Piceatannol	1	1
Pine Cone	1	1
Pomegranate Peel	1	1
Poria cocos	1	1
Prickly Pear Cactus	1	1
Procyanidin B2	1	1
Pterostilbene	1	1
Puerarin	1	1
Pulsatilla pratensis	1	1
Punicalagin	1	1
Purslane	1	1
Red Marine Algae	1	1
Reishi Mushroom	1	1
Rock-rose	1	1
Rose	1	1
Rosemary	1	1
Rutin	1	1
Saikosaponin	1	1
Sea buckthorn	1	1
Silver (nanoparticles)	1	1
Silymarin	1	1
Skullcap: Chinese	1	1
Strawberry	1	1
Tanshinone IIA	1	1
Terminalia	1	1
Theaflavins	1	1
Tongkat Ali	1	1
Toona sinensis	1	1
Ursolic Acid	1	1
Verbascoside	1	1
Verbena officinalis	1	1
Vitamin B-12	1	1
Vitamin B-6	1	1
Vitexins	1	1
Wogonin	1	1
Wormwood	1	1

Name	AC	CK
Oseltamivir (trade name Tamiflu)	11	135
Zanamivir	2	60
Neuraminidase inhibitors	1	40
Aspirin	2	12
Ibuprofen	2	12
Acetaminophen	1	10
Paracetamol	1	10
Electronic Cigarettes	4	9
Brevetoxin	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	2
Red tide	1	2
Cadmium	1	1
Lovastatin	1	1
Statin Drugs	1	1

Name	AC	CK
Qigong	1	30
Acupuncture	1	20
Homeopathic Treatment	2	20
Nasal Irrigation	1	20
Sunlight exposure	4	14
Drinking a Hot Beverage	1	10
Empathy	1	10
Placebo Effect	1	10
Sauna Therapy	1	10
Dietary Modification: Less Acid/More Alkaline Foods	1	2
Dietary Modification: Low Carbohydrate/Ketogenic	1	2
Grounding: Contact with the Earth	1	2
Sunlight Exposure: UVB Light	1	2

Name	AC	CK
Vaccination: Influenza	33	364
Vaccination: All	17	188
Face Masks (Lack of Safety and Ineffectiveness Research)	9	84
Face Masks: Cloth	4	32
Nocebo Effect	1	10

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Cloth masks might facilitate transmission of pathogens when used repeatedly without adequate sterilization.Nov 12, 2017

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Pubmed Data : BMJ Glob Health. 2021 01 ;6(1). PMID: 33472840

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Pubmed Data : Cochrane Database Syst Rev. 2010(3):CD006821. Epub 2010 Mar 17. PMID: 20238351

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Common Cold, Upper Respiratory Infections

Therapeutic Actions : Nasal Irrigation

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Studies examining the efficacy of the influenza vaccination and safety of these vaccinations are of poor methodological quality and the impact of confounders is high, suggesting a wide gap between vaccination policy and the evidence of its use.Oct 28, 2006

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Pubmed Data : BMJ. 2006 Oct 28 ;333(7574):912-5. PMID: 17068038

Article Published Date : Oct 28, 2006

Study Type : Meta Analysis

Additional Links

Diseases : Influenza, Vaccine-induced Toxicity

Additional Keywords : Vaccine Research

Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza

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The use of N95 respirators compared with surgical masks is not associated with a lower risk of laboratory-confirmed influenza.Apr 30, 2020

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A polyphenol-rich beverage reduces symptoms associated with the common cold.Oct 01, 2010

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Pubmed Data : Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID: 20487584

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Flavonoids, Polyphenols

Diseases : Common Cold

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A proprietary extract from the echinacea plant (Echinacea purpurea) enhances systemic immune response during a common cold.Aug 01, 2005

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Pubmed Data : Phytother Res. 2005 Aug;19(8):689-94. PMID: 16177972

Additional Keywords : Significant Treatment Outcome

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Boehmeria jamaicensis has therapeutic vale in the treatment of the common cold.Dec 01, 2007

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Pubmed Data : West Indian Med J. 2007 Dec;56(6):487-90. PMID: 18646490

Article Published Date : Dec 01, 2007

Study Type : Human Study

Additional Links

Substances : Boehmeria jamaicensis

Diseases : Common Cold

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Broccoli sprout homogenates increases virus-induced peripheral blood NK cell granzyme B production.Dec 31, 2015

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Pubmed Data : PLoS One. 2016 ;11(1):e0147742. Epub 2016 Jan 28. PMID: 26820305

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts

Diseases : Influenza A

Pharmacological Actions : Immunomodulatory

Additional Keywords : Plant Extracts

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Broccoli sprouts have a positive effect on the nasal response to live attenuated influenza virus in smokers.Dec 31, 2013

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Pubmed Data : Br J Nutr. 2010 Oct;104(7):998-1006. Epub 2010 May 21. PMID: 20487575

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Fermented Foods and Beverages, Lactobacilius bulgaricus, Yoghurt

Diseases : Common Cold, Low Immune Function: Natural Killer Cells

Pharmacological Actions : Immunomodulatory

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Continual intake of a probiotic drink containing Lactobacillus brevis led to a reduction in the incidence of influenza, especially in subjects not inoculated with influenza vaccine.Nov 30, 2014

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Pubmed Data : Lett Appl Microbiol. 2014 Dec ;59(6):565-71. Epub 2014 Oct 30. PMID: 25294223

Article Published Date : Nov 30, 2014

Study Type : Human Study

Additional Links

Substances : Lactobacillus Brevis, Probiotics

Diseases : Influenza

Pharmacological Actions : Immunomodulatory

Additional Keywords : Natural Substances Versus Drugs, Risk Reduction

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Continuous daily ingestion of 1073R-1-yogurt may help prevent infection with influenza A virus subtype H3N2 in elderly subjects with weakened immunity.May 15, 2019

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Pubmed Data : Acta Odontol Scand. 2019 May 16:1-8. Epub 2019 May 16. PMID: 31094267

Article Published Date : May 15, 2019

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Pubmed Data : Nutrients. 2022 Dec 30 ;15(1). Epub 2022 Dec 30. PMID: 36615837

Echinaforce Hotdrink is as effective as oseltamivir in the early treatment of confirmed influenza virus infections with a reduced risk of complications and adverse events.Nov 30, 2015

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Pubmed Data : Curr Ther Res Clin Exp. 2015 Dec ;77:66-72. Epub 2015 Apr 20. PMID: 26265958

Article Published Date : Nov 30, 2015

Study Type : Human Study

Additional Links

Substances : Echinacea

Diseases : Influenza

Pharmacological Actions : Antiviral Agents

Additional Keywords : Risk Reduction, Superiority of Natural Substances versus Drugs

Problem Substances : Oseltamivir (trade name Tamiflu)

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Effects of air pollutants on occurrences of influenza-like illness and laboratory-confirmed influenza in Hefei, China.Dec 31, 2018

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Pubmed Data : Int J Biometeorol. 2019 Jan ;63(1):51-60. Epub 2018 Oct 31. PMID: 30382350

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Influenza

Additional Keywords : Risk Factors

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Efficacy and safety of AP-Bio®(KalmCold®) in participants with uncomplicated upper respiratory tract viral infection.Apr 30, 2023

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Pubmed Data : Complement Ther Med. 2023 May ;73:102934. Epub 2023 Feb 24. PMID: 36842634

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Pubmed Data : mBio. 2020 Jan 21 ;11(1). Epub 2020 Jan 21. PMID: 31964741

Mao-to, a Japanese herbal medicine, is more effective than Oseltamivir in controlling fever due to type A influenza infection in children. Feb 01, 2007

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Pubmed Data : Phytomedicine. 2007 Feb;14(2-3):96-101. Epub 2006 Dec 1. PMID: 17141491

Article Published Date : Feb 01, 2007

Study Type : Human Study

Additional Links

Substances : Japanese Herbal Formula: Mao-to

Diseases : Fever, Influenza A

Additional Keywords : Superiority of Natural Substances versus Drugs

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Natural propolis may be an effective remedy for greating acute and chronic rhinopharyngitis (common cold) in children.Jul 01, 1995

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Pubmed Data : Rom J Virol. 1995 Jul-Dec;46(3-4):115-33. PMID: 9179964

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Pubmed Data : Prescrire Int. 2007 Feb;16(87):9-11. PMID: 17323516

Article Published Date : Feb 01, 2007

Study Type : Human Study

Additional Links

Diseases : Childhood Infections, Influenza, Vaccine-induced Toxicity

Problem Substances : Oseltamivir (trade name Tamiflu)

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Pubmed Data : Eur J Nutr. 2022 Aug 30. Epub 2022 Aug 30. PMID: 36042048

Article Published Date : Aug 29, 2022

Study Type : Human Study

Additional Links

Substances : Black Tea, Green Tea

Diseases : Bronchiectasis, Influenza, Lower Respiratory Infections, Pneumonia

Pharmacological Actions : Prophylactic Agents

Additional Keywords : Risk Reduction

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The 2014-2015 influenza vaccine was an antigenic mismatch, however, even in the context of antigenic mismatch, there is a generally limited antibody response following the vaccination.Oct 30, 2017

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Pubmed Data : Clin Infect Dis. 2017 Oct 30 ;65(10):1644-1651. PMID: 29020179

Article Published Date : Oct 30, 2017

Study Type : Human Study

Additional Links

Diseases : Influenza

Anti Therapeutic Actions : Vaccination: Influenza

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The administration of oral maoto granules to healthy adults with seasonal influenza was well tolerated and associated with equivalent clinical and virological efficacy to oseltamivir or zanamivir.Jul 31, 2012

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Pubmed Data : J Infect Chemother. 2012 Aug ;18(4):534-43. Epub 2012 Feb 16. PMID: 22350323

Article Published Date : Jul 31, 2012

Study Type : Human Study

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Pubmed Data : Complement Ther Med. 2016 Dec ;29:229-234. Epub 2016 Nov 2. PMID: 27912951

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Homeopathic Medicine: All

Diseases : Common Cold

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The intake of lactoferrin attenuates infectious diseases, including summer colds.Feb 25, 2020

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Pubmed Data : J Microbiol Immunol Infect. 2020 Feb 26. Epub 2020 Feb 26. PMID: 32151562

Article Published Date : Feb 25, 2020

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Pubmed Data : Homeopathy. 2016 Feb ;105(1):71-7. Epub 2015 Aug 4. PMID: 26828000

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Pubmed Data : Proc Natl Acad Sci U S A. 2018 01 30 ;115(5):1081-1086. Epub 2018 Jan 18. PMID: 29348203

Article Published Date : Jan 29, 2018

Study Type : Human Study

Additional Links

Diseases : Influenza A

Additional Keywords : Increased Risk, Vaccine Shedding

Anti Therapeutic Actions : Vaccination: Influenza

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This homeopathic treatment may be a useful component of an integrated symptomatic therapy for the common cold in patientsFeb 28, 2006

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Pubmed Data : Explore (NY). 2006 Mar ;2(2):109-14. PMID: 16781624

Article Published Date : Feb 28, 2006

Study Type : Human Study

Additional Links

Substances : Homeopathic Medicine: All

Diseases : Common Cold, Upper Respiratory Infections

Additional Keywords : Phytotherapy, Plant Extracts

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Treatment with Echinacea Plus tea at early onset of cold or flu symptoms was effective for relieving these symptoms in a shorter period of time than a placebo.Aug 01, 2000

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Pubmed Data : J Altern Complement Med. 2000 Aug;6(4):327-34. PMID: 10976979

Article Published Date : Aug 01, 2000

Study Type : Human Study

Additional Links

Substances : Echinacea

Diseases : Cold and Flu, Common Cold, Influenza, Upper Respiratory Infections

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Pubmed Data : Viruses. 2020 10 8 ;12(10). Epub 2020 Oct 8. PMID: 33050000

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Pubmed Data : J Microbiol Immunol Infect. 2022 May 18. Epub 2022 May 18. PMID: 35650006

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Pubmed Data : Cell Res. 2014 Oct 7. Epub 2014 Oct 7. PMID: 25287280

Article Published Date : Oct 06, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Diseases : H1N1 Infection, H5N1 Infection, Influenza A

Pharmacological Actions : Antiviral Agents

Additional Keywords : MicroRNA, Plant Extracts, Traditional Chinese Medicine

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Administration of isoliquiritigenin reduced lung viral titers and morbidity of mice infected with the PR8/H1N1 virus.Sep 30, 2015

Anti-influenza A virus effects of fructan from Welsh onion.Oct 14, 2012

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Pubmed Data : Food Chem. 2012 Oct 15 ;134(4):2164-8. Epub 2012 Apr 13. PMID: 23442670

Article Published Date : Oct 14, 2012

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Onion

Diseases : Influenza A

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts

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Antiviral effects of curcumin derivatives as potent inhibitors of influenza H1N1 neuraminidase.Apr 03, 2020

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Pubmed Data : Virologie. 1986 Apr-Jun;37(2):121-3. PMID: 3727395

Article Published Date : Apr 01, 1986

Study Type : Animal Study

Additional Links

Substances : Beet

Diseases : H1N1 Infection, Influenza A

Pharmacological Actions : Viral Hemagglutinin Inhibitor

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Beneficial effect of Indigo Naturalis on acute lung injury induced by influenza A virus.Dec 20, 2020

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Pubmed Data : J Agric Food Chem. 2007 Dec 12;55(25):10194-9. Epub 2007 Nov 8. PMID: 17988090

Article Published Date : Dec 12, 2007

Study Type : Animal Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Human Flu, Human Influenza, Influenza A

Pharmacological Actions : Antiviral Agents, Tumor Necrosis Factor (TNF) Alpha Enhancer

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Curcumin alleviates macrophage activation and lung inflammation induced by influenza virus infection.Dec 31, 2016

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Pubmed Data : Virol J. 2020 09 9 ;17(1):136. Epub 2020 Sep 9. PMID: 32907596

Article Published Date : Jan 08, 2020

Study Type : Animal Study

Additional Links

Substances : Echinacea

Diseases : Common Cold, Coronavirus Infection

Pharmacological Actions : Antiviral Agents

Additional Keywords : Plant Extracts

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Inactivation of avian influenza viruses on porous and non-porous surfaces is enhanced by elevating absolute humidity.Jul 31, 2017

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Pubmed Data : Transbound Emerg Dis. 2017 Aug ;64(4):1254-1261. Epub 2016 Apr 5. PMID: 27059695

Article Published Date : Jul 31, 2017

Study Type : Environmental

Additional Links

Diseases : Influenza A

Additional Keywords : High Humidity

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Isoquercetin inhibit influenza A and B viruses. Nov 01, 2010

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Pubmed Data : Antiviral Res. 2010 Nov;88(2):227-35. Epub 2010 Sep 6. PMID: 20826184

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Isoquercitrin

Diseases : Influenza A, Influenza B

Pharmacological Actions : Antiviral Agents

Additional Keywords : Drug Synergy, Plant Extracts

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Juice of Citrullus lanatus var. citroides inhibits the entry and propagation of influenza viruses.Dec 31, 2020

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Pubmed Data : Nutrients. 2023 Jul 28 ;15(15). Epub 2023 Jul 28. PMID: 37571299

Article Published Date : Jul 27, 2023

Study Type : Animal Study

Additional Links

Substances : Lactoferrin

Diseases : H5N1 Infection, Inflammation, Influenza

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

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Leonurine protects against H1N1 infection-induced pneumonia in mice.Sep 22, 2021

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Pubmed Data : Pathog Dis. 2021 Sep 23 ;79(7). PMID: 34543397

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Pubmed Data : PLoS Pathog. 2023 May ;19(5):e1011406. Epub 2023 May 18. PMID: 37200384

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Pubmed Data : Int J Immunopathol Pharmacol. 2007 Apr-Jun;20(2):349-54. PMID: 17624247

Article Published Date : Mar 31, 2007

Study Type : Animal Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Influenza

Pharmacological Actions : Antiviral Agents

Additional Keywords : Natural Substance/Drug Synergy

Problem Substances : Oseltamivir (trade name Tamiflu)

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Obesity-related microenvironment promotes emergence of virulent influenza virus strains.Mar 02, 2020

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Pubmed Data : mBio. 2020 Mar 3 ;11(2). Epub 2020 Mar 3. PMID: 32127459

Article Published Date : Mar 02, 2020

Study Type : Animal Study

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Diseases : Influenza, Obesity

Additional Keywords : Risk Factors

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Oligonol may act as an anti-aging molecule by modulating SIRT1/autophagy/AMPK pathways.Jan 31, 2016

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Pubmed Data : Nutr Res Pract. 2016 Feb ;10(1):3-10. Epub 2016 Jan 8. PMID: 26865910

Article Published Date : Jan 31, 2016

Study Type : Animal Study

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Substances : Lychee, Oligonol

Diseases : Aging, Influenza

Pharmacological Actions : Autophagy Up-regulation, SIRT1 Activator, Viral Hemagglutinin Inhibitor

Additional Keywords : Plant Extracts

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Oral administration of lactobacilli from human intestinal tract protects mice against influenza virus infection.Jul 01, 2010

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Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses.Jan 17, 2022

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Pubmed Data : Commun Biol. 2022 03 18 ;5(1):242. Epub 2022 Mar 18. PMID: 35304580

Article Published Date : Jan 17, 2022

Study Type : Animal Study, In Vitro Study

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Substances : Sulforaphane

Diseases : Common Cold, Coronavirus Infection

Pharmacological Actions : Antiviral Agents

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Synergistic combination of N-acetylcysteine and ribavirin to protect from lethal influenza viral infection in a mouse model.Dec 31, 2003

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Pubmed Data : Environ Health. 2010 Sep 3 ;9:55. Epub 2010 Sep 3. PMID: 20815876

Article Published Date : Sep 02, 2010

Study Type : Environmental

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Diseases : Influenza A

Additional Keywords : High Humidity, Risk Reduction

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This study provides insights on the molecular antiviral mechanisms of curcumin and its potential use as an antiviral agent for enveloped viruses.Dec 31, 2012

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Pubmed Data : Front Pharmacol. 2022 ;13:952660. Epub 2022 Aug 19. PMID: 36059950

Article Published Date : Dec 31, 2021

Study Type : Review

Additional Links

Substances : Andrographolide

Diseases : Coronavirus Infection, Influenza

Pharmacological Actions : Antiviral Agents

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A mixture of echinacea and hop extracts endowed with cytoprotective, immunomodulatory and antiviral properties.Oct 15, 2023

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Pubmed Data : Nutrients. 2023 Oct 16 ;15(20). Epub 2023 Oct 16. PMID: 37892456

Article Published Date : Oct 15, 2023

Study Type : In Vitro Study

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Substances : Echinacea, Hops

Diseases : Influenza

Pharmacological Actions : Antioxidants, Antiviral Agents, Immunomodulatory, Nrf2 activation

Additional Keywords : Plant Extracts

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A review of the protective effects of korean red ginseng against viral infections. Sep 30, 2016

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Pubmed Data : Virol J. 2011 Dec 14 ;8(1):538. Epub 2011 Dec 14. PMID: 22168277

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Pubmed Data : PLoS One. 2015 ;10(9):e0138075. Epub 2015 Sep 25. PMID: 26406906

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Pelargonium sidoides

Diseases : Candida Albicans, Coronaviridae Infections, Helicobacter Pylori Infection, Influenza, Streptococcus pyogenes, Upper Respiratory Tract Symptoms

Pharmacological Actions : Anti-Bacterial Agents, Anti-Infective Agents, Antifungal Agents, Antiviral Agents, Immunomodulatory

Additional Keywords : Plant Extracts

[+]

An in vitro antiviral evaluation of punicalagin toward influenza A virus.Dec 31, 2023

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Pubmed Data : Avicenna J Phytomed. 2024 ;14(4):496-504. PMID: 38952775

Article Published Date : Dec 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Punicalagin

Diseases : Influenza A

Pharmacological Actions : Antiviral Agents

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View the Evidence: 532 Abstracts with Cold and Flu Research

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A meta-analysis based on sixteen trials reveals that the majority of studies report positive results for Echinacea in the prevention and treatment of the common cold.Jan 01, 2000

Acupuncture may have a therapeutic effect on the common cold.Dec 01, 2004

Anti-influenza with green tea catechins.Jun 29, 2021

Cloth masks might facilitate transmission of pathogens when used repeatedly without adequate sterilization.Nov 12, 2017

Echinacea is effective in the prevention of symptoms of the rhinovirus-induced common cold. Feb 01, 2006

Echinacea use reduces the incidence and duration of the common cold.Jul 01, 2007

Effect of micronutrient supplements on influenza and other respiratory tract infections.Dec 31, 2020

Extra dose of vitamin C based on a daily supplementation shortens the common cold.Dec 31, 2017

Gargling with tea and its ingredients may have a preventative effect for influenza infection. Dec 31, 2015

Healthy adults who receive the inactivated influenza vaccine only have a 1% lower risk of experiencing influenza over a single influenza season and a 3.4% lower risk of experiencing influenza-like illness.Jan 01, 2018

Inactivated flu vaccines have not been proven to be effective or safe in preventing influenza in healthy children under two. Sep 01, 2009

Influenza vaccination for healthcare workers who work with the elderly has no effect on laboratory-proven influenza, pneumonia or deaths from pneumonia. Jan 01, 2010

Meta-analyses suggest that regular hand hygiene provided a significant protective effect and facemask use provided a non-significant protective effect.Dec 31, 2016

Oseltamivir for treatment of influenza in infants less than one year results in complications in 54% of the patients with the most serious of which were meningitis in 1 infant (1%), pneumonia in 9 (6%), and otitis media in 2 (1%)Jun 01, 2010

P. sidoides might offer symptom relief in acute bronchitis, rhinosinusitis and the common cold.Oct 21, 2013

Saline nasal irrigation may have therapeutic value for acute upper respiratory tract infections.Jan 01, 2010

Studies examining the efficacy of the influenza vaccination and safety of these vaccinations are of poor methodological quality and the impact of confounders is high, suggesting a wide gap between vaccination policy and the evidence of its use.Oct 28, 2006

Supplementation with elderberry was found to substantially reduce upper respiratory symptoms. Jan 31, 2019

The data is inconclusive as to whether or not neuraminidase inhibitors are effective at preventing and treating influenza in healthy adults.Oct 01, 2010

The evidence for a lower risk of influenza and influenza-like illness in the elderly with vaccination is limited by biases in the design or conduct of the studies.Jan 01, 2018

The meta-analysis produced a corroboration that vitamin D supplement has a preventive effect on influenza.Dec 31, 2020

The use of N95 respirators compared with surgical masks is not associated with a lower risk of laboratory-confirmed influenza.Apr 30, 2020

There is a lack of evidence for the effectiveness of influenza vaccines in adults aged 65 years or older.Oct 25, 2011

There is little evidence supporting the belief that vaccines are effective in preventing influenza in healthy adults.Jan 01, 2010

There is no solid evidence available supporting the belief that vaccines are effective in preventing influenza in the elderly.Jan 01, 2010

We concluded that there is no credible evidence that vaccination of healthy people under the age of 60, who are healthcare workers caring for the elderly, affects influenza complications in those cared for. Jan 01, 2006

Echinacea purpurea is efficacious in patients with a common cold.Jan 01, 2001

Lysine supplementation reduces diarrheal morbidity in children and respiratory morbidity in men in Ghana.Oct 01, 2010

A combination of fruit and vegetable powder extract reduces symptoms associated with the common cold.Aug 23, 2010

A dietary supplement containing probiotic bacteria plus vitamins and minerals reduce the incidence and severity of symptoms in common cold infections in adults. Jul 01, 2005

A Pelargonium Sidoides root extract is effective and safe in patients with the common cold.Jan 31, 2019

A polyphenol-rich beverage reduces symptoms associated with the common cold.Oct 01, 2010

A proprietary extract from the echinacea plant (Echinacea purpurea) enhances systemic immune response during a common cold.Aug 01, 2005

A yeast-based fermentation byproduct reduces cold and flu incidence in nonvaccinated individuals.Feb 01, 2010

A yeast-based fermentation byproduct reduces cold and flu symptom duration and severity.Feb 01, 2008

Absolute humidity as a deterministic factor affecting seasonal influenza epidemics in Japan.Dec 31, 2010

Acute effects of air pollution on influenza-like illness in Nanjing, China: A population-based study.Feb 29, 2016

Adverse effects of aspirin, acetaminophen, and ibuprofen on immune function, viral shedding, and clinical status in rhinovirus-infected volunteers.Nov 30, 1990

AGE supplementation may enhance immune cell function and may be partly responsible for the reduced severity of colds and flu reported.Jan 31, 2016

Ambient fine particles may increase the risk of exposure to influenza in China especially on cooler days.Dec 31, 2016

Ambient particulate matter 2.5 concentrations were significantly associated with influenza-like illness risk.Feb 10, 2016

American Ginseng is safe and effective in reducing relative risk and duration of respiratory symptoms associated with "cold and flu" in adults. Mar 01, 2006

American ginseng is safe, well tolerated, and potentially effective for preventing acute respiratory illness due to influenza and respiractory syncytial virus infections.Jan 01, 2004

Among healthcare workers for the elderly, taking green tea catechins and theanine may be effective prophylaxis for influenza infection.Jan 01, 2011

An echinacea extract has been demonstrated to be effective in preventing the common cold in persons who actively participate in sports.Sep 01, 2006

An extract of Baptisa (Wild Indigo), echinacea and thuja is safe and effective in the treatment of upper respiratory infections.Nov 01, 2005

An herbal preparation containing echinacea, propolis, and vitamin C in preventing respiratory tract infections in children.Mar 01, 2004

Andrographis has therapeutic activity against upper respiratory tract infections.Mar 01, 2010

Annual influenza vaccination hampers the development of virus-specific CD8(+) T cell responses necessary to protect against influenza infection. Nov 01, 2011

Associations between source-specific particulate matter and respiratory infections in New York state adults.Jan 20, 2020

At best, the the influenza vaccine is only 58% effective.Feb 01, 2011

Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise.Sep 01, 2013

Beetroot juice during periods of psychological stress protects against cold symptoms.Mar 31, 2019

Biobran/MGN-3 could be a novel agent with prophylactic effects against a wide spectrum of respiratory viral infections.Nov 18, 2021

Boehmeria jamaicensis has therapeutic vale in the treatment of the common cold.Dec 01, 2007

Broccoli sprout homogenates increases virus-induced peripheral blood NK cell granzyme B production.Dec 31, 2015

Broccoli sprouts have a positive effect on the nasal response to live attenuated influenza virus in smokers.Dec 31, 2013

Childhood immune imprinting to influenza A shapes birth year-specific risk during seasonal H1N1 and H3N2 epidemics.Nov 30, 2019

Clinician empathy reduces the duration and severity of the common cold in patients.Jul 01, 2009

Consumption of yoghurt fermented with L. bulgaricus OLL1073R-1 augmented natural killer cell activity and reduced the risk of catching the common cold in elderly individuals.Oct 01, 2010

Continual intake of a probiotic drink containing Lactobacillus brevis led to a reduction in the incidence of influenza, especially in subjects not inoculated with influenza vaccine.Nov 30, 2014

Continuous daily ingestion of 1073R-1-yogurt may help prevent infection with influenza A virus subtype H3N2 in elderly subjects with weakened immunity.May 15, 2019

Daily dietary probiotic supplementation for 6 months is a safe and effective way to reduce fever, rhinorrhea, and cough incidence and duration and antibiotic prescription incidence, as well as the number of missed school days for children 3-5 years of ageFeb 01, 2011

Daily intake of bifidobacteria provides benefit related to cold/flu outcomes during acute stress. Feb 13, 2015

Daily supplementation with 5000 IU vitamin D3 reduces influenza-like illness in healthcare workers.Dec 29, 2022

Differential expression of serum exosome microRNAs and cytokines in influenza A and B patients.Feb 01, 2021

Doses of vitamin C in excess of 1 g daily taken shortly after onset of a cold.Sep 30, 2001

Drinking cocoa could activate natural immunity. Feb 29, 2016

Echinacea appears effective in preventing upper respiratory tract infections in children.Dec 01, 2005

Echinacea has a preventive effect against the common cold. Dec 31, 2011

Echinacea modules human gene expression in a manner consistent with its reported ability to reduce both the duration and intensity of cold and flu symptoms.Oct 01, 2003

Echinaforce Hotdrink is as effective as oseltamivir in the early treatment of confirmed influenza virus infections with a reduced risk of complications and adverse events.Nov 30, 2015

Cold and Flu

View the Evidence:
532 Abstracts with Cold and Flu Research