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Colon Cancer
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467 Substances Researched for Colon Cancer
Name
AC
CK
Focus
Curcumin
73
99
Vitamin D
13
46
Sulforaphane
17
35
Coffee
3
31
Nuts
3
31
Apples
8
30
Flavonoids
21
25
Lactoferrin
10
23
Fermented Foods and Beverages
16
22
Fiber
9
21
Resveratrol
16
20
Vitamin C
15
20
Probiotics
12
19
Berberine
13
18
Garlic
7
17
Polyphenols
13
17
Black Currant
3
16
Ginger
8
15
Pterostilbene
10
15
Anthocyanins
10
14
Ginsenosides
12
14
Prebiotics
4
14
Blueberry
7
13
Ellagic Acid
9
13
Shikonin
9
13
Banana
3
12
Cryptoxanthin
2
12
Folic Acid
2
12
Fucoidan
11
12
Lutein
2
12
Magnesium
2
12
Silibinin
6
12
Vegetables: All
2
12
Walnut
8
12
Antineoplastons
2
11
Chaga Mushroom (Inonotus obliquus)
9
11
Fruit: All
2
11
Lettuce
2
11
Soy
6
11
Blackberry
6
10
Genistein
7
10
Lichens
6
10
Luteolin
9
10
Omega-3 Fatty Acids
6
10
Psyllium
1
10
Vitamin C: Intravenous
1
10
Astaxanthin
6
9
Cranberry
4
9
Grape
7
9
Thymoquinone
6
9
EGCG (Epigallocatechin gallate)
6
8
Flaxseed
5
8
Lignans
6
8
Myricetin
7
8
Quercetin
5
8
Rutin
6
8
Adlay
5
7
Apigenin
5
7
Green Tea
5
7
Lactobacillus paracasei
6
7
Limonoids
2
7
Mushrooms: All
3
7
Nigella sativa (aka Black Seed)
4
7
Raspberry
3
7
Wogonin
2
7
Ashwagandha
5
6
Asiatic Acid
5
6
Caffeic Acid
4
6
Calcium
3
6
Cannabidiol
4
6
Cannabinoids
4
6
Ginseng
4
6
Ginseng (Korean)
4
6
Isoflavones
4
6
Lactobacillus probiotics
2
6
Lactobacillus rhamnosus
3
6
Licorice
4
6
Lingonberry
2
6
Mustard: Field/Turnip
2
6
Nobiletin
4
6
Oats
4
6
Olive
5
6
Selenium
4
6
Ursolic Acid
6
6
Whey
4
6
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
2
5
Arctigenin
4
5
Beta-glucan
3
5
Cannabis
3
5
Curry Leaves
3
5
Deguelin
3
5
Fucoxanthin
3
5
Honey
5
5
Indian Gooseberry
1
5
Lactobacillus Acidophilus
4
5
Lactobacillus casei
3
5
Moringa oleifera
3
5
Olive leaf extract
4
5
Oyster Mushroom
4
5
P-Coumaric Acid
4
5
Piperlongumine
3
5
Pomegranate
4
5
Rice
3
5
Rosemary
4
5
Shiitake Mushroom
3
5
Wheat Grass
4
5
White Mulberry
1
5
Xanthohumol
5
5
6-Shogaol
4
4
Apple
3
4
Apple Pectin
2
4
Beans: All
2
4
Bee Propolis
4
4
Black Tea
3
4
Capsaicin
2
4
Carnosic Acid
3
4
Catechin
3
4
Chokeberry
4
4
Cucurbitacin B
3
4
Cucurbitacin E
3
4
Fisetin
4
4
Ginseng (American)
3
4
Gold (nanoparticles)
4
4
Grape Seed Extract
3
4
Guar gum
2
4
Guava
3
4
Hesperidin
2
4
Maitake Mushroom
2
4
Melatonin
4
4
Miso
2
4
Modified Citrus Pectin
2
4
Neem
3
4
Nettle
3
4
Olive Oil
3
4
Oridonin
3
4
Phloretin
4
4
Piceatannol
4
4
Piperine
4
4
Sage
3
4
Spinach
2
4
Urolithin A
3
4
Vitamin A
2
4
Vitamin E: Gamma-Tocopherol
2
4
Wheat Bran
3
4
Wheat Germ
3
4
Yoghurt
2
4
Acai
2
3
Antineoplaston A3
1
3
Apple Polyphenols
3
3
Bacopa
2
3
Baicalein
2
3
Bee Venom
2
3
Beta Sitosterol
3
3
Bilberry
2
3
Brown Rice
2
3
Butyrate
3
3
Carnosol
3
3
Carotenoids
2
3
Carrot
3
3
Chrysin
2
3
Curcuma Purpurascens
2
3
Cyanidin 3-glucoside
3
3
Emodin
3
3
Frankincense
2
3
Gallic Acid
2
3
Garlic: Aged
2
3
Genipin
3
3
Ginkgo biloba
2
3
Grapefruit
2
3
Hydroxytyrosol
3
3
Inositol Hexaphosphate
2
3
Kimchi
2
3
Lactobacillus fermentum
2
3
Lion's Mane (Hericium Erinaceus)
2
3
Lotus
3
3
Lychee
2
3
Mangiferin
2
3
Manuka Honey
3
3
Mistletoe
1
3
Nexrutine (Phellodendrom)
2
3
Oak
2
3
Orange
2
3
Phellinus Linteus
3
3
Propolis: Brazillian
2
3
Prunella vulgaris
3
3
Puerarin
2
3
Reishi Mushroom
2
3
Rhubarb
3
3
Rose
3
3
Saccharomyces Boulardii
2
3
Sesamol
2
3
Strawberry
3
3
Sweet Potato
3
3
Sweet Potato: Purple
3
3
Tanshinone IIA
3
3
Tart Cherry
2
3
Theaflavins
3
3
Vitamin E
2
3
Vitamin E: Gamma-tocotrienol
3
3
Watermelon
2
3
Wheat: Fermented
3
3
White Tea
2
3
Zerumbone
2
3
Achiote
1
2
Aleurone
2
2
Allicin
2
2
Aloe Vera
2
2
Andrographis
2
2
Antrodia camphorata
2
2
Arginine
1
2
Avenanthramides
2
2
Avocado
2
2
Bael
2
2
Barley
1
2
Beet
2
2
Benzyl isothiocyanate
2
2
Berbamine
2
2
Berries: All
2
2
Betulinic acid
2
2
Bifidobacterium
1
2
Bifidobacterium Longum
1
2
Bitter Melon
2
2
Black Pepper
1
2
Black Raspberry
2
2
Broccoli Sprouts
2
2
Bromelain
1
2
Buckwheat
1
2
Bufalin
2
2
Burdock
2
2
Caffeine
1
2
Camel Milk
2
2
Camu Camu
1
2
Cannabigerol
1
2
Capparis spinosa (caper)
2
2
Caraway
1
2
Caraway Oil
1
2
Celastrol
2
2
Chickpea
1
2
Chlorophyll
1
2
Citrus aurantium
2
2
Citrus naringin
1
2
Cloudberry
1
2
Coconut
1
2
Common bean
1
2
Coriandrum sativum
1
2
Cumin
1
2
Curcumol
1
2
D-Limonene
2
2
DHA (Docosahexaenoic Acid)
2
2
Daidzein
2
2
Dandelion
1
2
Eriodictyol
1
2
Estrone
1
2
Eucalyptus
1
2
Evodiamine
1
2
Flaxseed Oil
1
2
Gac
1
2
Garcinia indica
1
2
Glycyrrhiza uralensis
1
2
Gold
2
2
Gotu Kola
1
2
Grains: All
1
2
Guduchi
2
2
Isothiocyanates
2
2
Jambul
1
2
Kefir
2
2
Krill
1
2
Lactobacillus Brevis
1
2
Lactobacillus plantarum
2
2
Lactobacillus rhamnosus GG
2
2
Lemon
1
2
Lemongrass
1
2
Lentils
1
2
Lentinan
1
2
Lycopene
2
2
Medicinal Mushrooms
2
2
Methionine
1
2
Mustard Greens
1
2
Mustard Seeds
1
2
Nutmeg
1
2
Oleuropein
2
2
Oolong tea
1
2
Orange: Mandarin
1
2
Oregano
2
2
Orthosiphon
1
2
Palm Oil
1
2
Pectin
1
2
Persimmon
1
2
Plum
2
2
Potato
2
2
Potato: Pigmented
1
2
Prickly Pear Cactus
2
2
Pumpkin Seed Oil/Meal
1
2
Pumpkin Seeds
2
2
Raisins
2
2
Red Wine
1
2
Rose Hips
2
2
Rosemaric Acid
1
2
Rosmarinic acid
1
2
Rye
1
2
Solanum Glaucophyllum
1
2
Soy Protein
1
2
Spirulina
2
2
Sprouts
1
2
Stearic Acid (stearate)
1
2
Tangeretin
2
2
Tannic Acid
2
2
Tetrahydrocurcumin
1
2
Tomato
2
2
Tricin
1
2
Turmeric
2
2
Vitamin B-12
1
2
Vitamin D3
1
2
Vitamin E: delta-tocopherol
1
2
Vitamin K2
1
2
Water
1
2
Water: Deuterium Depleted
2
2
Yerba Santa
1
2
Amygdalin
1
1
Anandamide
1
1
Angelica
1
1
Apricot Kernel
1
1
Arabinoxylans
1
1
Arnica
1
1
Artesunate
1
1
Asparagus
1
1
Astragaloside
1
1
Bacillus coagulans
1
1
Bai Zhu
1
1
Bamboo
1
1
Banaba
1
1
Banana Peel
1
1
Bergamot orange
1
1
Bifidobacterium Bifidum
1
1
Bifidobacterium Breve
1
1
Biochanin A
1
1
Black Bean
1
1
Bran
1
1
CLA (Conjugated Linoleic Acid)
1
1
Cannabinoids: Synthetic
1
1
Cardamonin
1
1
Carob
1
1
Chamomile
1
1
Cherry: All Varieties
1
1
Chitosan
1
1
Chlorogenic Acid
1
1
Cinnamon
1
1
Clove
1
1
Corn Silk
1
1
Coumestrol
1
1
Crocin
1
1
Curcuma phaeocaulis
1
1
Daikon radish
1
1
Dogwood
1
1
EPA (Eicosapentaenoic Acid)
1
1
Echinacea
1
1
Egg
1
1
Endive (Cichorium endivia. L )
1
1
Enterodiol
1
1
Enterolactone
1
1
Eugenol
1
1
Euphorbia cotinifolia
1
1
Fenugreek
1
1
Ferulic acid
1
1
Fish Oil
1
1
Formononetin
1
1
Galbanic Acid
1
1
Gallotannins
1
1
Geraniol
1
1
Gingerol
1
1
Ginseng (Asian)
1
1
Ginseng (Siberian)
1
1
Glycitein
1
1
Goji
1
1
Grapes
1
1
Graviola
1
1
Haematococcus pluvialis
1
1
Hazelnut
1
1
Henna
1
1
Homeopathic Medicine: All
1
1
Honeysuckle
1
1
Honokiol
1
1
Horse Chestnut
1
1
Infection/Infectitious Agent Byproducts (Beneficial)
1
1
Kanuka Honey
1
1
Kiwifruit
1
1
Lactobacillus reuteri
1
1
Lauric acid
1
1
Legumes
1
1
Lime: Key
1
1
MSM (Methylsulfonylmethane)
1
1
Magnolia
1
1
Mango
1
1
Mastic gum
1
1
Melissa (Lemonbalm)
1
1
Milk Thistle
1
1
Molasses
1
1
Mugwort
1
1
Myrica rubra
1
1
Naringenin
1
1
Nordihydroguaiaretic acid (NDGA)
1
1
Oleocanthal
1
1
Onion
1
1
Oyster Mushroom: Indian
1
1
Palmitoylethanolamide
1
1
Parthenolide
1
1
Peach
1
1
Peanut
1
1
Pear
1
1
Peony
1
1
Peppermint
1
1
Phyllanthus emblica
1
1
Phytosterols
1
1
Pine Cone
1
1
Piperidines
1
1
Pistachio nut
1
1
Polyunsaturated Fatty Acids (PUFAs)
1
1
Pomegranate flower
1
1
Pomelo
1
1
Propolis: Bee
1
1
Pumpkin
1
1
Purple Carrots
1
1
Purslane
1
1
Quince
1
1
Radish
1
1
Red Marine Algae
1
1
Red Yeast Rice
1
1
Riboflavin (Vitamin B-2)
1
1
Rice Bran
1
1
Rice: Black
1
1
Rooibos
1
1
Royal Jelly
1
1
Ruta Graveolens
1
1
Saffron
1
1
Salvia divinorum
1
1
Schisandra
1
1
Sea buckthorn
1
1
Seaweed: Brown
1
1
Sesame Seeds
1
1
Silver (nanoparticles)
1
1
Silymarin
1
1
Solasodine glycoalkaloids
1
1
Sorghum
1
1
Soup
1
1
Spearmint
1
1
St. Johns Wort
1
1
Stevia
1
1
Stilbenes
1
1
Sweet Cherry
1
1
Thistle
1
1
Thyme
1
1
Toad
1
1
Tocotrienol: Gamma
1
1
Trichosanthes Kirilowii
1
1
Triphala
1
1
Tyrosol
1
1
Ume (Japanese apricot)
1
1
Vanillin
1
1
Vitamin B-3 (Niacin)
1
1
Vitamin K
1
1
Vitex Agnus
1
1
Wasabi
1
1
Willow Bark
1
1
Xanthones
1
1
Zataria multiflora
1
1
cottonseed oil (gossypol)
1
1
pistachios
1
1
23 Problem Substances Researched for Colon Cancer
Name
AC
CK
Focus
Sugar Sweetened Beverages
2
12
Foods: High Glycemic Load
1
10
Meat
1
10
Casein
2
4
Sucrose
2
4
Benzo(a)pyrene
1
2
Bisphenol A
2
2
Chlorinated Water
1
2
Ferrous Fumarate
1
2
Fructose
1
2
Glucose
1
2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
1
2
Sodium lauryl sulfate
1
2
2,4-Dichlorophenoxyacetic acid
1
1
Adrenaline
1
1
Aromatase Inhibitor Drugs
1
1
Artificial Sweeteners
1
1
Aspartame
1
1
Atorvastatin
1
1
Bisphosphonates
1
1
Doxorubicin
1
1
Saccharin
1
1
Sodium Cyclamate
1
1
8 Therapeutic Actions Researched for Colon Cancer
Name
AC
CK
Focus
Sunlight exposure
3
23
Exercise
2
3
Light-Emitting Diodes (LEDs) Therapy
2
3
Dietary Modification: Low Carbohydrate/Ketogenic
1
2
Light Therapy
1
2
Thermal Therapy: Far-Infrared
1
2
Heat Therapy
1
1
Microbiota Transfer Therapy
1
1
4 Problematic Actions Researched for Colon Cancer
Name
AC
CK
Focus
Western Diet
8
16
Gamma Irradiation: "Cold Pasteurization"
1
2
Microwave Cooking
1
1
Stress
1
1
Research Articles
954
Cumulative Knowledge Score
1543
Overall Research Rating
EXCELLENT
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[+]
Bioactive compounds from kefir and their potential benefits on health.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2021 ;2021:9081738. Epub 2021 Oct 27. PMID:
34745425
Article Published Date
: Dec 31, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Kefir
Diseases
:
Breast Cancer
,
Colitis
,
Colon Cancer
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antimicrobial
,
Antioxidants
,
Immunomodulatory
[+]
Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.
Sep 25, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Sep 26 ;6:33711. Epub 2016 Sep 26. PMID:
27665923
Article Published Date
: Sep 25, 2016
Study Type
: Meta Analysis
Additional Links
Substances
:
Coffee
Diseases
:
Colon Cancer
,
Endometrial Cancer
,
Liver Cancer
,
Lung Cancer
,
Melanoma
,
Oral Cancer
,
Prostate Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Nut consumption was significantly associated with a reduced risk of cancer incidence.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Rev. 2015 Jul ;73(7):409-25. PMID:
26081452
Article Published Date
: Jun 30, 2015
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nuts
Diseases
:
Colon Cancer
,
Pancreatic Cancer
Additional Keywords
:
Risk Reduction
[+]
Review: there is a consistently strong inverse correlations with solar UVB for 15 types of cancers.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2012 Jan ;32(1):223-36. PMID:
22213311
Article Published Date
: Jan 01, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D
Diseases
:
Bladder Cancer
,
Breast Cancer
,
Cervical Cancer
,
Colon Cancer
,
Colorectal Cancer
,
Endometrial Cancer
,
Esophageal Cancer
,
Hodgkin Lymphoma
,
Lung Cancer
,
Non-Hodgkin Lymphoma
,
Ovarian Cancer
,
Pancreatic Cancer
,
Renal Cancer
,
Vulvar Cancer
Therapeutic Actions
:
Sunlight exposure
Pharmacological Actions
:
Chemopreventive
[+]
A blackcurrant product regulated the microbiota of volunteers and decreased the activity of βeta glucuronidase.
Feb 28, 2014
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2014 Mar ;28(3):416-22. Epub 2013 May 15. PMID:
23674271
Article Published Date
: Feb 28, 2014
Study Type
: Human Study
Additional Links
Substances
:
Black Currant
,
Lactoferrin
,
Lutein
,
Prebiotics
Diseases
:
Clostridium Infections
,
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Enzyme Inhibitors
Additional Keywords
:
Beta-glucuronidase
,
Plant Extracts
,
Risk Reduction
[+]
Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.
Mar 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2006 Mar;136(3 Suppl):816S-820S. PMID:
16484572
Article Published Date
: Mar 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Garlic
Diseases
:
Colon Cancer
,
Liver Cancer
,
Low Immune Function: Natural Killer Cells
,
Pancreatic Cancer
Additional Keywords
:
Drug Side Effect Attenuation
,
Plant Extracts
[+]
Antineoplastons (A10 Injection and AS2-1) might be useful as adjunctive therapy in addition to HAI after hepatectomy in colorectal metastases to the liver.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(3):e0120064. Epub 2015 Mar 19. PMID:
25790229
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Antineoplastons
Diseases
:
Cancer Metastasis
,
Colon Cancer
,
Colorectal Cancer
Additional Keywords
:
Drug: 5-flourouracil
,
Significant Treatment Outcome
[+]
Beta-cryptoxanthin synergistically enhances the antitumoral activity of oxaliplatin.
Sep 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cancer Res. 2015 Oct 1 ;21(19):4398-409. Epub 2015 May 28. PMID:
26023082
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study, Human Study, In Vitro Study
Additional Links
Substances
:
Cryptoxanthin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Chemotherapeutic Synergy: Oxaliplatin
[+]
Coffee consumption was associated with 26% lower odds of developing colorectal cancer.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2016 Apr ;25(4):634-9. PMID:
27196095
Article Published Date
: Mar 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Coffee
Diseases
:
Colon Cancer
,
Rectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Dose Response
,
Risk Reduction
[+]
Fecal microbiota changes with fermented kimchi intake regulated either formation or advancement of colon adenoma.
Feb 28, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Biochem Nutr. 2021 Mar ;68(2):139-148. Epub 2020 Dec 26. PMID:
33879965
Article Published Date
: Feb 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Kimchi
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Gastrointestinal Agents
,
Gastroprotective
[+]
High dose folic acid supplementation is associated with a significant reduction in the recurrrence of colon cancers.
Jul 28, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Jul 28;14(28):4492-8. PMID:
18680228
Article Published Date
: Jul 28, 2008
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Higher consumption of nuts may be associated with a significantly reduced incidence of cancer recurrence and death in patients with stage III colon cancer.
Feb 27, 2018
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2018 Feb 28:JCO2017755413. Epub 2018 Feb 28. PMID:
29489429
Article Published Date
: Feb 27, 2018
Study Type
: Human Study
Additional Links
Substances
:
Nuts
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Chemopreventive
,
COLON CANCER
,
nuts
,
Risk Reduction
[+]
Higher dietary glycemic load and total carbohydrate intake were statistically significant associated with an increased risk of recurrence and mortality in stage III colon cancer patients.
Nov 20, 2012
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 2012 Nov 21 ;104(22):1702-11. Epub 2012 Nov 7. PMID:
23136358
Article Published Date
: Nov 20, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Carcinogens
Problem Substances
:
Foods: High Glycemic Load
[+]
Individuals consuming the highest intakes of dietary fiber have reduced risks of incident colorectal adenoma and distal colon cancer.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26269366
Article Published Date
: Aug 11, 2015
Study Type
: Human Study
Additional Links
Substances
:
Fiber
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
,
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Myofascial pain as assessed by tender trigger points and 25(OH)D deficiency showed a significant association with cancer.
Jul 05, 2017
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2017 Jul 6:1-7. Epub 2017 Jul 6. PMID:
28682182
Article Published Date
: Jul 05, 2017
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
,
Vitamin D
Diseases
:
Colon Cancer
,
Magnesium Deficiency
,
Vitamin D Deficiency
Additional Keywords
:
Risk Factors
[+]
Plaintain seeds improve the colonic flora and butyrate in patients resected for colonic cancer.
Oct 01, 1996
Click here to read the entire abstract
Pubmed Data
: Scand J Gastroenterol. 1996 Oct;31(10):1011-20. PMID:
8898423
Article Published Date
: Oct 01, 1996
Study Type
: Human Study
Additional Links
Substances
:
Psyllium
Diseases
:
Colon Cancer
,
Dysbiosis
[+]
Sulforaphane has a novel chemopreventive mechanism in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase (HDAC). I
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2007 Feb;232(2):227-34. PMID:
17259330
Article Published Date
: Feb 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
,
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Chemopreventive
,
Enzyme Inhibitors
,
Histone deacetylase inhibitor
[+]
The consumption of apples is inversely related to the risk of colorectal cancer.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Rev Environ Health. 2009 Jan-Mar;24(1):59-74. PMID:
19476292
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Apples
Diseases
:
Colon Cancer
,
Colorectal Cancer
[+]
This study reports that a meat and sugary dietary pattern increased, while a plant-based dietary pattern decreased the risk of colorectal cancer.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2015 ;14:8. Epub 2015 Jan 15. PMID:
25592002
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Colon Cancer
,
Colorectal Cancer
Additional Keywords
:
Risk Factors
Problem Substances
:
Meat
,
Sugar Sweetened Beverages
[+]
Total vegetable intake, total fruit intake, and lettuce, apple, and banana consumption is associated with a reduced risk for colorectal cancer.
Jan 01, 1996
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1996;25(3):297-304. PMID:
8771572
Article Published Date
: Jan 01, 1996
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Banana
,
Fruit: All
,
Lettuce
,
Vegetables: All
Diseases
:
Colon Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Vitamin C administration by intravenous infusion Increases tumor ascorbate content in patients with colon cancer.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2020 ;10:600715. Epub 2021 Jan 11. PMID:
33505915
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C: Intravenous
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
6-gingerol a component of ginger is extensively metabolized in H-1299 human lung cancer cells.
Nov 13, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Agric Food Chem. 2012 Nov 14 ;60(45):11372-7. Epub 2012 Nov 6. PMID:
23066935
Article Published Date
: Nov 13, 2012
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginger
Diseases
:
Cancers
,
Carcinoma: Non-Small-Cell Lung
,
Colon Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Biotransformation
,
Plant Extracts
[+]
Morus alba flavonoid extract and doxorubicin induce a dose dependent cell death in HT-29 cell line.
Mar 30, 2016
Click here to read the entire abstract
Pubmed Data
: Cell Mol Biol (Noisy-le-grand). 2016 Mar 31 ;62(3):72-7. Epub 2016 Mar 31. PMID:
27064876
Article Published Date
: Mar 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
White Mulberry
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
,
COLON CANCER
,
Dose Response
,
Plant Extracts
,
White Mulberry
[+]
Probiotic lactobacillus had inhibitory effects of on the growth of human colonic carcinoma cell line HT-29.
Jan 09, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2017 Jan 10 ;22(1). Epub 2017 Jan 10. PMID:
28075415
Article Published Date
: Jan 09, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Lactobacillus probiotics
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2018 Jan ;124:42-48. Epub 2017 Oct 12. PMID:
29031537
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Silibinin
Diseases
:
Cancers: Drug Resistant
,
Cancers: Multi-Drug Resistant
,
Colon Cancer
Pharmacological Actions
:
Chemosensitizer
,
Glucose transporter-1 (GLUT1) expression down-regulation
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.
Jan 01, 2018
Click here to read the entire abstract
Pubmed Data
: Cells Tissues Organs. 2018 ;206(1-2):46-53. Epub 2018 Jul 24. PMID:
30041241
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-cancer
,
Anti-metastatic
,
Anti-Proliferative
,
Cyclooxygenase 2 Inhibitors
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
[+]
Sulforaphane regulates xenobiotic metabolism phase II and III enzymes differently in colorectal cancer and untransformed epithelial colon cells.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 Nov-Dec;68(8):1338-1348. Epub 2016 Aug 16. PMID:
27636860
Article Published Date
: Oct 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cytoprotective
,
Nrf2 activation
Additional Keywords
:
Gene Expression Regulation
,
Selective Cytotoxicity
[+]
The present study shows that lichen compounds demonstrated strong antioxidant, antimicrobial, and anticancer properties.
Oct 14, 2012
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2012 Oct 15 ;19(13):1166-72. Epub 2012 Aug 22. PMID:
22921748
Article Published Date
: Oct 14, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Lichens
Diseases
:
Colon Cancer
,
Melanoma
Pharmacological Actions
:
Antimicrobial
,
Antioxidants
,
Chemopreventive
Additional Keywords
:
Antimicrobial
,
Antioxidants
,
Chemopreventive
,
COLON CANCER
,
Lichens
,
melanoma
[+]
The present work emphasizes the potential of berries in chemoprevention, especially CRC chemoprevention.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2015;2015:154164. Epub 2015 Jun 9. PMID:
26180579
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Black Currant
,
Blackberry
,
Blueberry
,
Cranberry
,
Indian Gooseberry
,
Lingonberry
,
Raspberry
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Apoptotic
,
Caspase-8 activation
,
Chemopreventive
Additional Keywords
:
Dietary Concentrations
,
Growing Your Own Food
,
Procyanidins
[+]
verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Genom Data. 2015 Sep 1 ;5:189-191. PMID:
26309812
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Mushrooms: All
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Epigenetic Modification In Cancer
,
Gene Expression Regulation
[+]
Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.
Jan 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2014 Feb ;53 Suppl 1:E107-18. Epub 2013 Jun 13. PMID:
23761018
Article Published Date
: Jan 31, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Wogonin
Diseases
:
Cancers: Drug Resistant
,
Cancers: Multi-Drug Resistant
,
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
PI3K/Akt/signaling suppression
Additional Keywords
:
Cancer Glycolysis
,
Resistance Reversal
[+]
"Phase I clinical studies of antineoplaston A3 injections."
Jan 01, 1987
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1987 ;13 Suppl 1:17-29. PMID:
3569012
Article Published Date
: Jan 01, 1987
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston A3
Diseases
:
Bladder Cancer
,
Colon Cancer
,
Epithelioma
,
Prostate Cancer
Pharmacological Actions
:
Antineoplastic Agents
[+]
Case report: long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Surg Today. 2003 ;33(6):448-53. PMID:
12768372
Article Published Date
: Jan 01, 2003
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases
:
Colon Cancer
,
Liver Cancer
,
Liver Cancer: Metastatic
,
Liver Metastasis From Colon Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Spontaneous regression of advanced transverse colon cancer with remaining lymph node metastasis.
May 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Surg Case Rep. 2020 May 11 ;6(1):100. Epub 2020 May 11. PMID:
32394212
Article Published Date
: May 10, 2020
Study Type
: Human: Case Report
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Tumor Regression
[+]
Spontaneous regression of colorectal liver metastasis.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Clin J Gastroenterol. 2018 Aug ;11(4):263-267. Epub 2018 Mar 15. PMID:
29546568
Article Published Date
: Jul 31, 2018
Study Type
: Human: Case Report
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Regression
[+]
Spontaneous regression of transverse colon cancer with high-frequency microsatellite instability.
Jan 14, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Surg Oncol. 2019 Jan 15 ;17(1):19. Epub 2019 Jan 15. PMID:
30646898
Article Published Date
: Jan 14, 2019
Study Type
: Human: Case Report, Review
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Tumor Regression
[+]
Spontaneous regression of transverse colon cancer: a case report.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Surg Case Rep. 2017 Dec ;3(1):65. Epub 2017 May 10. PMID:
28488173
Article Published Date
: Nov 30, 2017
Study Type
: Human: Case Report
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Regression
[+]
This is the first report showing complete regression of a colon adenoma after intratumoural injection with Viscum album extract.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Gastrointestin Liver Dis. 2014 Dec ;23(4):449-52. PMID:
25532007
Article Published Date
: Nov 30, 2014
Study Type
: Human: Case Report
Additional Links
Substances
:
Mistletoe
Diseases
:
Colon Cancer
,
Colon Polyps
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Disease Regression
[+]
Preventive effects of Korean red ginseng on experimentally induced colitis and colon carcinogenesis.
Apr 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Tradit Complement Med. 2020 May ;10(3):198-206. Epub 2020 Apr 25. PMID:
32670814
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
The inhibitory effect of oridonin on colon cancer was mediated by deactivation of TGF-β1/Smads-PAI-1 signaling pathway in vitro and vivo.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2019 ;12:7467-7476. Epub 2019 Sep 11. PMID:
31686852
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Oridonin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords
:
Dose Response
[+]
"Antineoplaston AS2-1 showed an antimetastatic effect against post-operative lung metastases from colon cancer through G1 cell arrest and the subsequent induction of apoptosis."
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2005 Mar ;13(3):389-95. PMID:
15706406
Article Published Date
: Mar 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases
:
Cancer Metastasis
,
Colon Cancer
,
Lung Cancer: Metastatic
,
Post-Operative Lung Metastasis of Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
[+]
"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo.
Dec 21, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Dec 22 ;58(24):12999-3005. Epub 2010 Nov 17. PMID:
21082859
Article Published Date
: Dec 21, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
[+]
"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo."
Dec 21, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Dec 22 ;58(24):12999-3005. Epub 2010 Nov 17. PMID:
21082859
Article Published Date
: Dec 21, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
[+]
3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2019 Feb 1 ;448:20-30. Epub 2019 Feb 1. PMID:
30716361
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
[+]
A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Jan;48(1):390-5. Epub 2009 Oct 25. PMID:
19861145
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Curcumin
,
Green Tea
Diseases
:
Colon Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Drug Synergy
[+]
A compound found exclusively in irradiated dietary fats may promote colon carcinogenesis in animals treated with a chemical carcinogen.
Jan 01, 2002
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2002;44(2):189-91. PMID:
12734067
Article Published Date
: Jan 01, 2002
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Gamma Irradiation
Anti Therapeutic Actions
:
Gamma Irradiation: "Cold Pasteurization"
[+]
A high vitamin D diet reduced proliferation, increased differentiation and apoptosis, and in parallel, upregulated mRNA expression of the calcium-sensing receptor in the colon of mice.
Mar 06, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Steroid Biochem Mol Biol. 2015 Mar 7. Epub 2015 Mar 7. PMID:
25758239
Article Published Date
: Mar 06, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Calcium
,
Vitamin D
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
A sucrose-rich diet induces mutations in the rat colon.
Aug 01, 2002
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2002 Aug 1;62(15):4339-45. PMID:
12154038
Article Published Date
: Aug 01, 2002
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
,
DNA damage
,
Oxidative Stress
Problem Substances
:
Sucrose
[+]
A water-extracted polysaccharide from Lentinus edodes exerts direct antitumor effects by inducing apoptosis in colon cancer cells.
Nov 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Nov 21. Epub 2016 Nov 21. PMID:
27888812
Article Published Date
: Nov 20, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Shiitake Mushroom
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bax/Bcl2 ratio: Increase
,
Caspase-3 Activation
,
NF-kappaB Inhibitor
Additional Keywords
:
Polysaccharides
[+]
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Nov 01, 2001
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2001 Nov;22(11):1871-5. PMID:
11698351
Article Published Date
: Nov 01, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Folic Acid
,
Methionine
,
Vitamin B-12
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
Anti Therapeutic Actions
:
Western Diet
[+]
Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.
Mar 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut Liver. 2017 Mar 15 ;11(2):243-252. PMID:
27965474
Article Published Date
: Mar 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Acai
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acute addition of Vitamin C to the basolateral membrane maintains low intracellular pH for a longer period which could halt or prevent tumor formation.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2017 ;44(1):377-387. Epub 2017 Nov 13. PMID:
29132138
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Cancer Res. 2021 ;11(5):2252-2263. Epub 2021 May 15. PMID:
34094682
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bromelain
,
Cysteine (see N-Acetylcysteine)
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Gemcitabine
[+]
Adenosine and P. distasonis have previously been shown to be anti-inflammatory in the colon and we postulate their reduction could promote tumorigenesis by de-repressing inflammation.
Jan 31, 1973
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut. 1973 Feb ;14(2):89-93. PMID:
PMC4540493
Article Published Date
: Jan 31, 1973
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
,
Inflammation
,
Obesity
Additional Keywords
:
Microbiome
,
Microbiota
,
Risk Factors
[+]
Adlay bran ethanolic extract suppressed 1,2-dimethylhydrazine-indued preneoplastic lesions of the colon.
Jul 13, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Jul 14 ;58(13):7616-23. PMID:
20536243
Article Published Date
: Jul 13, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Adlay
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Adlay
,
Anti-Inflammatory Agents
,
Chemopreventive
,
COLON CANCER
,
Cyclooxygenase 2 Inhibitors
,
Plant Extracts
[+]
Administration of the probiotic candidate DTA81 can have beneficial effects on the initial stages of CRC development.
Dec 13, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Microorganisms. 2020 Dec 14 ;8(12). Epub 2020 Dec 14. PMID:
33327620
Article Published Date
: Dec 13, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus paracasei
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Aged garlic extract suppressed the proliferative activity in adenoma and adenocarcinoma lesions, but showed no effect on normal colon mucosa.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Mar ;33(3):1131-40. Epub 2014 Dec 30. PMID:
25573280
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
,
NF-kappaB Inhibitor
Additional Keywords
:
Selective Antiproliferation
[+]
Alantolactone exhibits antiproliferative and apoptosis-promoting properties in colon cancer model
Aug 29, 2021
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2021 Aug 30. Epub 2021 Aug 30. PMID:
34460036
Article Published Date
: Aug 29, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Elecampane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
American ginseng exerts the chemopreventive effects by anti-inflammatory and antioxidant mechanisms.
Aug 06, 2015
Click here to read the entire abstract
Pubmed Data
: J Proteome Res. 2015 Aug 7 ;14(8):3336-47. Epub 2015 Jul 10. PMID:
26136108
Article Published Date
: Aug 06, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (American)
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemopreventive
[+]
An aqueous extract of fermented barley with Lactobacillus plantarum dy-1 had a greater apoptotic rate than 5-fluorouracil.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Environ Sci. 2017 Jan ;30(1):10-21. PMID:
28245895
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
,
Fermented Foods and Beverages
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
An extract of Curcuma purpurascens suppressed the proliferation of HT-29 colon cancer cells and triggered the induction of apoptosis through mitochondrial-dependent pathway.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15:15. Epub 2015 Feb 5. PMID:
25652758
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcuma Purpurascens
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-9 Activation
Additional Keywords
:
Dose Response
[+]
Annatto has possible chemopreventive effects through modulation of the cryptal cell proliferation but not at the initiation stage of colon carcinogenesis.
Apr 03, 2005
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2005 Apr 4 ;582(1-2):146-54. PMID:
15781219
Article Published Date
: Apr 03, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Achiote
Diseases
:
Colon Cancer
,
DNA damage
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Anthocyanin containing purple fleshed potatoes suppressed colon tumorigenesis via elimination of colon cancer stem cells.
Aug 13, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Aug 14. Epub 2015 Aug 14. PMID:
26383537
Article Published Date
: Aug 13, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Potato: Pigmented
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Cancer Stem Cells
,
Natural Substances Versus Drugs
,
Plant Extracts
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
Anti-proliferative effect of leaf extracts of Eucalyptus citriodora against human cancer cells in vitro and in vivo.
Nov 30, 2012
Click here to read the entire abstract
Pubmed Data
: Indian J Biochem Biophys. 2012 Dec ;49(6):451-7. PMID:
23350280
Article Published Date
: Nov 30, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Eucalyptus
Diseases
:
Cervical Cancer
,
Colon Cancer
,
Liver Cancer
,
Lung Cancer
,
Neuroblastoma
,
Ovarian Cancer
,
Prostate Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2017 ;11:103-121. Epub 2016 Dec 28. PMID:
28096658
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curry Leaves
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Apoptotic
[+]
Apigenin could inhibit the growth of cisplatin-resistant colon cancer cells in vitro and in vivo.
Feb 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J BUON. 2019 Mar-Apr;24(2):488-493. PMID:
31127995
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apigenin
Diseases
:
Cancers: Drug Resistant
,
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Chemosensitizer
[+]
Apple juice upregulates antioxidant-associated genes in the rat colon and liver, which may account for apple's anti-cancer activity.
Aug 01, 2000
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2000 Aug;21(8):1461-7. PMID:
20652274
Article Published Date
: Aug 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Polyphenols
Diseases
:
Colon Cancer
,
Liver Cancer
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
[+]
Apple pectin and Bifidobacterium longum inhibit colorectal tumors in transgenic mice.
Oct 01, 2000
Click here to read the entire abstract
Pubmed Data
: Exp Anim. 2000 Oct;49(4):305-7. PMID:
11109558
Article Published Date
: Oct 01, 2000
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Apple Pectin
,
Bifidobacterium
,
Bifidobacterium Longum
Diseases
:
Colon Cancer
,
Colorectal Cancer
,
Colorectal Tumors
[+]
Apple pectin decrease the number and incidence of colon cancer.
Mar 01, 1997
Click here to read the entire abstract
Pubmed Data
: J Exp Clin Cancer Res. 1997 Mar;16(1):33-8. PMID:
9148858
Article Published Date
: Mar 01, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Apple Pectin
Diseases
:
Colon Cancer
Additional Keywords
:
Bacteriostatic
[+]
Apple polysaccharide extracts could be used in combination therapy for the prevention of colitis-associated colon cancer.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 ;67(1):177-90. Epub 2014 Nov 20. PMID:
25412264
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apples
Diseases
:
Colitis
,
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Apple total triterpenoid content induced apoptosis in MDA-MB-231 cells.
Sep 18, 2012
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2012 Sep 19 ;60(37):9430-6. Epub 2012 Sep 6. PMID:
22924395
Article Published Date
: Sep 18, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apples
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Colon Cancer
,
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Apples may exert their colon cancer protective effects through favorably altering gene patterns resulting in protection of cells against toxicological insults.
Jun 15, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2008 Jun 15;122(12):2647-55. PMID:
18351577
Article Published Date
: Jun 15, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Epigenetic Modification
[+]
Application of an unrestricted ketogenic diet delayed tumor growth in a mouse xenograft model.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2015 ;16(5):2061-8. PMID:
25773851
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Omega-3 Fatty Acids
Diseases
:
Colon Cancer
Therapeutic Actions
:
Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions
:
Antiproliferative
[+]
Arctigenin could be used to reduce the risk of colitis-associated cancer in patients with colitis.
Aug 26, 2020
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2020 Aug 27 ;491:162-179. Epub 2020 Aug 27. PMID:
32861708
Article Published Date
: Aug 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
[+]
As mono-therapy the natural isoflavone genistein has a powerful therapeutic effect in vivo on A431 and Colo205 tumors.
Apr 06, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Apr 7. Epub 2016 Apr 7. PMID:
27070087
Article Published Date
: Apr 06, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Colon Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
[+]
Asiatic acid could be used as an effective chemopreventive agent against 1,2-dimethylhydrazine induced colon carcinogenesis.
Dec 24, 2017
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2017 Dec 25 ;278:197-211. Epub 2017 Nov 6. PMID:
29108773
Article Published Date
: Dec 24, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Chemopreventive
[+]
Asiatic acid could be used as an effective chemopreventive agent against 1,2-dimethylhydrazine-induced colon carcinogenesis.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Mech Methods. 2017 Feb ;27(2):136-150. Epub 2017 Jan 11. PMID:
28004603
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Assessment of the anti-cancer efficiency of silver Moringa oleifera leaves nano-extract against colon cancer.
Sep 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2021 Oct 1 ;22(10):3267-3286. Epub 2021 Oct 1. PMID:
34711004
Article Published Date
: Sep 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
[+]
Astaxanthin exhibits anti-inflammatory and anti-cancer activity in a rat model of colon cnacer.
Apr 01, 2011
Click here to read the entire abstract
Pubmed Data
: Invest New Drugs. 2011 Apr;29(2):207-24. Epub 2009 Oct 30. PMID:
19876598
Article Published Date
: Apr 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Cancer Metastasis
,
Colon Cancer
,
Colorectal Cancer
,
Inflammation
Pharmacological Actions
:
Apoptotic
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Astaxanthin protects against chemically induced colonic pre-neoplastic progression in rats.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Fundam Clin Pharmacol. 2009 Apr;23(2):225-34. PMID:
19645817
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Colon Cancer
,
Inflammation
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Antiproliferative
[+]
Bacopa monieri has great potential for development of anticancer treatments.
Sep 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacogn Mag. 2017 Oct ;13(Suppl 3):S595-S606. Epub 2017 Oct 11. PMID:
29142420
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bacopa
,
Cucurbitacin B
,
Cucurbitacin E
Diseases
:
Breast Cancer
,
Cervical Cancer
,
Colon Cancer
,
Lung Cancer
Pharmacological Actions
:
Chemopreventive
,
Chemotherapeutic
[+]
Baicalein exerts potent S phase cell cycle arrest and pro-apoptotic effects in HCT-116 cells.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2015 Nov ;47(5):1749-58. Epub 2015 Sep 18. PMID:
26398706
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Microbiota
[+]
Bee venom could be applicable as an anti-colon cancer agent.
Oct 29, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2015 Oct 30. Epub 2015 Oct 30. PMID:
26561202
Article Published Date
: Oct 29, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Berberine and evodiamine regulate the expression of important genes that could be beneficial in colon cancer treatments.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Mar ;37(3):1637-1645. Epub 2017 Jan 17. PMID:
28098901
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
,
Evodiamine
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Chemotherapeutic
,
MicroRNA modulator
[+]
Berberine has a preventive effect on experimental colon cancer.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2010 Oct;35(20):2768-73. PMID:
21246838
Article Published Date
: Oct 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Berberine has an anti-tumor effect on colitis-associated colorectal cancer.
Jul 30, 2017
Click here to read the entire abstract
Pubmed Data
: Lab Invest. 2017 Jul 31. Epub 2017 Jul 31. PMID:
28759012
Article Published Date
: Jul 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
[+]
Berberine suppresses colon cancer cell proliferation by inhibiting the SCAP/SREBP-1 signaling pathway-mediated lipogenesis.
Dec 22, 2019
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2019 Dec 23 ;174:113776. Epub 2019 Dec 23. PMID:
31874145
Article Published Date
: Dec 22, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Beta-Cryptoxanthin and Hesperidin are potential cancer chemopreventive agents against tongue, colon, and lung cancers.
Jan 01, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Biomed Biotechnol. 2012 ;2012:516981. Epub 2011 Nov 24. PMID:
22174562
Article Published Date
: Jan 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Cryptoxanthin
,
Hesperidin
,
Orange: Mandarin
Diseases
:
Colon Cancer
,
Inflammation
,
Lung Cancer
,
Tongue Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Biostimulating gut microbiome with bilberry anthocyanin combo to enhance Anti-PD-L1 efficiency against murine colon cancer.
Jan 24, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Microorganisms. 2020 Jan 25 ;8(2). Epub 2020 Jan 25. PMID:
31991820
Article Published Date
: Jan 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemotherapeutic
,
Gastrointestinal Agents
[+]
Black raspberries attenuate colonic adenoma development in Apc Min mice.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Front. 2020 Sep ;1(3):234-242. Epub 2020 Sep 9. PMID:
34557678
Article Published Date
: Aug 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Black Raspberry
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Black seed oil has significant inhibitory effects against colon cancer in rats, without observable side effects.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2003;45(2):195-202. PMID:
12881014
Article Published Date
: Jan 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Blue LED irradiation inhibits cancer cell migration and invasion in vitro and in vivo.
Jan 17, 2017
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2017 Jan 18. Epub 2017 Jan 18. PMID:
28098340
Article Published Date
: Jan 17, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colon Cancer
,
Fibrosarcoma
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Boswellia serrate extract has great potential to suppress colon tumorigenesis.
Feb 27, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2017 Feb 28. Epub 2017 Feb 28. PMID:
28245338
Article Published Date
: Feb 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Buckwheat sprouts have an anti-inflammatory effect in lipopolysaccharide-activated human colon cancer cells and mice.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2008 Dec;72(12):3148-57. Epub 2008 Dec 7. PMID:
19060399
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Sprouts
Diseases
:
Colon Cancer
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Calcitriol enhanced the efficacy of irinotecan in growth inhibition and apoptosis induction.
Jul 24, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Cancer Ther. 2016 Jul 25. Epub 2016 Jul 25. PMID:
27458137
Article Published Date
: Jul 24, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Calcium and vitamin D may prevent Western-style diet-induced colonic tumors.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2009 Jan;30(1):88-92. Epub 2008 Nov 18. PMID:
19017685
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Calcium
,
Vitamin D
Diseases
:
Colon Cancer
,
Western-Style Diet Induced Toxicity
Anti Therapeutic Actions
:
Western Diet
[+]
Calcium supplementation may attenuate the hyperproliferation and hyperplasia induced in the mouse colon by a Western-style diet.
Nov 01, 1995
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 1995 Nov;16(11):2685-9. PMID:
7586187
Article Published Date
: Nov 01, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Calcium
Diseases
:
Colon Cancer
,
Western-Style Diet Induced Toxicity
Pharmacological Actions
:
Antiproliferative
[+]
Cannabidiol protected DNA from oxidative damage, increased endocannabinoid levels and reduced cell proliferation.
Jul 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Mol Med (Berl). 2012 Aug ;90(8):925-34. Epub 2012 Jan 10. PMID:
22231745
Article Published Date
: Jul 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antineoplastic Agents
,
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Endocannabinoid System
[+]
Cannabigerol hampers colon cancer progression in vivo and selectively inhibits the growth of colorectal cancer cells.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2014 Dec ;35(12):2787-97. Epub 2014 Sep 30. PMID:
25269802
Article Published Date
: Nov 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cannabigerol
,
Cannabinoids
,
Cannabis
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Selective Antiproliferation
[+]
Caraway supplementation prevents oxidative stress and inhibits chemically-induced lesions in rats with colon cancer.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2006 Aug;58(8):1121-30. PMID:
16872560
Article Published Date
: Aug 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Caraway
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antioxidants
[+]
Carnosic acid appears to alleviate adipocity-related acceleration of colon tumor formation.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2014 Dec ;58(12):2274-85. Epub 2014 Oct 9. PMID:
25204550
Article Published Date
: Nov 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Interleukin-6 Downregulation
Additional Keywords
:
Plant Extracts
[+]
Cellulose fiber reduces the incidence of chemically-induced colon cancer in rats.
Oct 15, 1989
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 1989 Oct 15;49(20):5581-5. PMID:
2551490
Article Published Date
: Oct 15, 1989
Study Type
: Animal Study
Additional Links
Substances
:
Fiber
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Chemoprevention of azoxymethane-induced colon carcinogenesis by delta-tocotrienol.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2019 06 ;12(6):357-366. Epub 2019 Apr 2. PMID:
30940630
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Tocotrienol: Delta
,
Vitamin E
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Chemopreventive
[+]
Chemopreventive effect of germinated oat and its phenolic extract in a model of colon carcinogenesis.
Feb 09, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2020 Feb 10 ;9(2). Epub 2020 Feb 10. PMID:
32050698
Article Published Date
: Feb 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Oats
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Chemopreventive effects of silibinin on colitis-associated tumorigenesis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2018 ;2018:1562010. Epub 2018 Oct 25. PMID:
30498394
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Silibinin
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Interleukin-6 Downregulation
[+]
Chickpea flour inhibits the formation of precancerous lesions in mice, suggesting that they may reduce the risk for colon cancer incidence.
Sep 01, 2004
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2004 Sep-Oct;24(5A):3049-55. PMID:
15517915
Article Published Date
: Sep 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Chickpea
Diseases
:
Colon Cancer
[+]
Chinese olive fruit has promising potential in cancer treatment.
Nov 20, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Nov 21. Epub 2016 Aug 21. PMID:
27869910
Article Published Date
: Nov 20, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Olive
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chlorinated water influences the development of colorectal tumors with chromosomal instability.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(7):e0132435. Epub 2015 Jul 17. PMID:
26186212
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Clostridium Infections
,
Colon Cancer
Additional Keywords
:
Chromosomal Aberration
,
Microbiota
Problem Substances
:
Chlorinated Water
[+]
Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death.
Aug 13, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2015 Aug 14 ;6(23):19514-27. PMID:
26098775
Article Published Date
: Aug 13, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lemon
Diseases
:
Chronic Myeloid Leukemia
,
Colon Cancer
,
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Cloudberry and its compounds possess strong chemopreventive activity against colon cancer.
May 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 30. Epub 2016 May 30. PMID:
27270323
Article Published Date
: May 29, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cloudberry
,
Ellagic Acid
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Chemopreventive
[+]
Co-administration of antioxidant significantly increased plasma level of curcumin in animal models.
Nov 25, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2015 Nov 26. Epub 2015 Nov 26. PMID:
26608515
Article Published Date
: Nov 25, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic Acid
,
Curcumin
,
Gallic Acid
,
Rosmarinic acid
,
Vitamin C
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antioxidants
,
Antiproliferative
Additional Keywords
:
Increased Bioavailability
,
Metabolites
[+]
Co-treatments with Uro-A decreased IC50 values for both 5-FU and 5'DFUR and additionally arrested the cell cycle at the G2/M phase.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 May ;6(5):1460-9. PMID:
25857357
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
,
Urolithin A
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cell cycle arrest
,
Chemosensitizer
Additional Keywords
:
Drug: 5-flourouracil
,
Metabolites
,
Microbiota
[+]
Coconut significantly decreases the incidence and number of tumors in a rat model of colon cancer.
Apr 01, 2004
Click here to read the entire abstract
Pubmed Data
: Clin Chim Acta. 2004 Apr;342(1-2):203-10. PMID:
15026282
Article Published Date
: Apr 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Coconut
Diseases
:
Colon Cancer
[+]
Colon cancer prevention with walnuts.
Dec 08, 2019
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2019 Dec 9. Epub 2019 Dec 9. PMID:
31818852
Article Published Date
: Dec 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Walnut
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Gastrointestinal Agents
Additional Keywords
:
Risk Reduction
Anti Therapeutic Actions
:
Western Diet
[+]
Colon targeted curcumin microspheres laden with ascorbic acid for bioavailability enhancement.
Jul 15, 2018
Click here to read the entire abstract
Pubmed Data
: J Microencapsul. 2018 Jul 16:1-28. Epub 2018 Jul 16. PMID:
30010458
Article Published Date
: Jul 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Vitamin C
Diseases
:
Colon Cancer
Additional Keywords
:
Increased Bioavailability
[+]
Combining curcumin with guar gum may help increase its effectiveness in treating colon cancer.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Drugs Aging. 2007;24(11):945-55. PMID:
20614824
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Guar gum
Diseases
:
Colon Cancer
,
Colorectal Cancer
Additional Keywords
:
Natural Substance Synergy
[+]
Combining Rp1 with chemotherapeutic agents could circumvent drug resistance and improve treatment efficacy.
Mar 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2020 Mar 5 ;12(3). Epub 2020 Mar 5. PMID:
32151067
Article Published Date
: Mar 04, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colon Cancer
,
Lung Cancer
,
Ovarian Cancer
Pharmacological Actions
:
Apoptotic
,
Chemotherapeutic
[+]
Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
Sep 23, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 23;57(18):8587-90. PMID:
19711910
Article Published Date
: Sep 23, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic Acid
,
Curcumin
,
Ellagic Acid
,
Flavonoids
,
Polyphenols
,
Rutin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Coriandrum sativum has a protective role against the deleterious effects in lipid metabolism in experimental colon cancer.
Aug 01, 2000
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2000 Aug;71(3):457-63. PMID:
10940583
Article Published Date
: Aug 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Coriandrum sativum
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Cryptotanshinone alleviates chemotherapy-induced colitis in mice with colon cancer.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2021 01 ;163:105232. Epub 2020 Oct 4. PMID:
33027716
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Salvia miltiorrhiza
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Chemotherapy-Induced Toxicity: Irinotecan
,
Colitis
,
Colon Cancer
Pharmacological Actions
:
Chemoprotective Agents
,
Gastrointestinal Agents
,
Hypolipidemic
[+]
Cumin and black pepper prevent chemically-induced rat colon carcinogenesis.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2006;9(2):237-45. PMID:
16822210
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Black Pepper
,
Cumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Curcumin has chemopreventive properties during the promotion/progression stages of colon cancer.
Feb 01, 1999
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 1999 Feb 1;59(3):597-601. PMID:
9973206
Article Published Date
: Feb 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Apoptotic
,
Chemopreventive
[+]
Curcumin inhibits chemically-induced colonic lesions.
Nov 01, 1993
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 1993 Nov;14(11):2219-25. PMID:
8242846
Article Published Date
: Nov 01, 1993
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Curcumin inhibits colon polyp formation.
May 06, 2003
Click here to read the entire abstract
Pubmed Data
: Br J Cancer. 2003 May 6;88(9):1480-3. PMID:
12778080
Article Published Date
: May 06, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
,
Colon Polyps
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Curcumin inhibits muscle wasting in colon tumor bearing mice.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Oct;102(7):967-75. Epub 2009 Apr 27. PMID:
19393114
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cachexia
,
Colon Cancer
,
Muscle Atrophy
Pharmacological Actions
:
Proteasome Inhibitors
[+]
Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo.
Sep 15, 2008
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2008 Sep 15;68(18):7283-92. PMID:
18794115
Article Published Date
: Sep 15, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Proteasome Inhibitors
[+]
Curcumin may have therapeutic value in colon cancer prevention.
Oct 28, 1999
Click here to read the entire abstract
Pubmed Data
: Oncogene. 1999 Oct 28;18(44):6013-20. PMID:
10557090
Article Published Date
: Oct 28, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin mediates IL-6/STAT3 signaling pathway to repair intestinal mucosal injury induced by 5-FU chemotherapy for colon cancer.
Jan 31, 2021
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2021 Feb ;46(3):670-677. PMID:
33645034
Article Published Date
: Jan 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Interleukin-6 Downregulation
[+]
Curcumin prevents colon carcinogenesis.
Apr 01, 1999
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 1999 Apr;20(4):641-4. PMID:
10223193
Article Published Date
: Apr 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
,
Colon Polyps
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 2 Inhibitors
,
Enzyme Inhibitors
,
Nitric Oxide Inhibitor
[+]
Curcumin prevents the development of chemically-induced precancerous colonic lesions in male obese mice.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2012 Jan ;64(1):72-9. Epub 2011 Dec 15. PMID:
22172229
Article Published Date
: Jan 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
,
Colon Polyps
,
Precancerous Conditions
Pharmacological Actions
:
Chemopreventive
[+]
Curcumin protects against familial adenomatous polyposis and decreases intestinal bleeding as compared to NSAID drugs.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Biol Pharm Bull. 2009 Mar;32(3):382-8. PMID:
12050094
Article Published Date
: Mar 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
,
Colon Polyps
,
Intestinal Polyps
Pharmacological Actions
:
Antineoplastic Agents
,
Chemopreventive
[+]
Curcumin reduces intestinal inflammation and polyps, indicating its potential value for preventing colon cancer.
Oct 15, 2010
Click here to read the entire abstract
Pubmed Data
: J Interferon Cytokine Res. 2010 Oct 15. Epub 2010 Oct 15. PMID:
20950131
Article Published Date
: Oct 15, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
,
Gastrointestinal Inflammation
,
Intestinal Cancer
,
Intestinal Polyps
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curry leaves (M. koenigii) and Mustard Greens (B. juncea) inhibit colon and intestine neoplasms in a rat model.
Jan 01, 1996
Click here to read the entire abstract
Pubmed Data
: Invest New Drugs. 1996;14(4):365-9. PMID:
9157071
Article Published Date
: Jan 01, 1996
Study Type
: Animal Study
Additional Links
Substances
:
Curry Leaves
,
Mustard Greens
Diseases
:
Colon Cancer
[+]
Deguelin might be a potential therapeutic agent for treatment of colorectal cancer.
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: Dig Dis Sci. 2012 Nov ;57(11):2873-82. Epub 2012 May 24. PMID:
22623043
Article Published Date
: Oct 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Deguelin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
[+]
Delta and gamma tocopherols inhibit colon carcinogenesis.
Mar 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2012 Apr ;5(4):644-54. Epub 2012 Feb 24. PMID:
22366914
Article Published Date
: Mar 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E: delta-tocopherol
,
Vitamin E: Gamma-Tocopherol
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Dietary administration of garcinol effectively reduced the tumor size and incidence in the mouse colon.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2014 Sep ;58(9):1820-9. Epub 2014 Jul 1. PMID:
24981158
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Garcinia indica
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
,
Cyclin D1 Down-Regulation
,
Cyclooxygenase 2 Inhibitors
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice.
May 20, 2011
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2011 May 20. Epub 2011 May 20. PMID:
21621527
Article Published Date
: May 20, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
[+]
Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced mice.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2008;60(3):373-81. PMID:
18444172
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Beans: All
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Dietary curcumin inhibits forestomach, duodenal, and colon carcinogenesis in mice.
Nov 15, 1994
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 1994 Nov 15;54(22):5841-7. PMID:
7954412
Article Published Date
: Nov 15, 1994
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Colon Cancer
,
Gastric Cancer
,
Gastrointestinal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Dietary curcumin prevents colon carcinogenesis.
Jan 15, 1995
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 1995 Jan 15;55(2):259-66. PMID:
7812955
Article Published Date
: Jan 15, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Dietary flaxseed may be chemopreventive for intestinal and colon tumor development in mice possibly by increasing omega -3 fatty acid levels, lignans, and decreasing COX-1 and COX-2 levels.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2009;61(2):276-83. PMID:
19235044
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Lignans
,
Omega-3 Fatty Acids
Diseases
:
Colon Cancer
,
Intestinal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Cyclooxygenase Inhibitors
[+]
Dietary flaxseed meal containing high levels of omega-3 fatty acids and lignans is effective in preventing colon tumor development when compared with dietary corn meal possibly by increasing omega-3 fatty acid levels and decreasing COX-1 and COX-2 levels.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2006;54(2):216-22. PMID:
16898866
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Lignans
,
Omega-3 Fatty Acids
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
[+]
dietary flaxseed oil, containing high levels of omega-3 fatty acids, is effective in preventing colon tumor development when compared with dietary corn oil containing omega-6 fatty acids in rats.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2008 May;74(6):686-92. Epub 2008 Apr 30. PMID:
15749630
Article Published Date
: May 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Omega-3 Fatty Acids
Diseases
:
Colon Cancer
Additional Keywords
:
Omega 3/6 Ratio
,
Omega 6 Fatty Acids are Detrimental
[+]
Dietary intake of fermented kimchi prevented colitis-associated cancer.
Oct 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Biochem Nutr. 2020 Nov ;67(3):263-273. Epub 2020 Sep 17. PMID:
33293767
Article Published Date
: Oct 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Kimchi
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
NF-kappaB Inhibitor
[+]
Dietary intake of pterostilbene, a constituent of blueberries, inhibits colon carcinogenesis in rats.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2010 Jul;31(7):1272-8. Epub 2010 Jan 8. PMID:
20061362
Article Published Date
: Jul 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Pterostilbene
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Stilbenes
[+]
Dietary iron (ferrous fumarate) simulates intestinal tumorigenesis in mice.
Aug 31, 1992
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 1992 Aug 31;65(3):245-9. PMID:
1516040
Article Published Date
: Aug 31, 1992
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
Problem Substances
:
Ferrous Fumarate
[+]
Dietary selenium protects against chronic inflammation induced colon cancer in mice.
Jan 02, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2017 Jan 3:0. Epub 2017 Jan 3. PMID:
28045589
Article Published Date
: Jan 02, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Selenium
Diseases
:
Colon Cancer
,
Inflammation
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Dietary soy isoflavones and estrone protect ovariectomized mice from carcinogen-induced colon cancer.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2004 Jan;134(1):179-82. PMID:
14704314
Article Published Date
: Jan 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Estrone
,
Genistein
,
Soy
Diseases
:
Colon Cancer
[+]
Dietary supplementation with 180-day fermented dietary miso could act as a chemopreventive agent for colon carcinogenesis.
Dec 01, 2005
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2005 Dec;14(6):1559-64. PMID:
16273256
Article Published Date
: Dec 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Miso
,
Soy
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in mice with colitis.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Inflamm Bowel Dis. 2010 Dec;16(12):2012-21. PMID:
20848493
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bromelain
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
[+]
Dietary supplementation with pectin and guar gum significantly suppresses colon cancer incidence in rats.
May 01, 1992
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 1992 May;13(5):815-8. PMID:
1316814
Article Published Date
: May 01, 1992
Study Type
: Animal Study
Additional Links
Substances
:
Fiber
,
Guar gum
,
Pectin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Dietary tricin, a flavone present in rice, oats, barley, and wheat inhibits inflammation-related mouse colon carcinogenesis.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila Pa). 2009 Dec;2(12):1031-8. Epub 2009 Nov 24. PMID:
19934339
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grains: All
,
Oats
,
Rice
,
Tricin
Diseases
:
Colon Cancer
,
Inflammation
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Dietary whey protein protects against azoxymethane-induced colon tumors in male rats.
Apr 30, 2001
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2001 May ;10(5):555-8. PMID:
11352868
Article Published Date
: Apr 30, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Whey
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Dry beans inhibit azoxymethane-induced colon carcinogenesis in rats.
Dec 01, 1997
Click here to read the entire abstract
Pubmed Data
: J Nutr. 1997 Dec;127(12):2328-33. PMID:
9405582
Article Published Date
: Dec 01, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Beans: All
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2017 Aug ;46:100-108. Epub 2017 Mar 30. PMID:
28494341
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Persimmon
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
Ecklonia cava fucoidan has potential to stimulate natural killer cells in vivo.
Aug 30, 2021
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2021 Aug 31 ;185:111-121. Epub 2021 Jun 10. PMID:
34119543
Article Published Date
: Aug 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Colon Cancer
,
Lung Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Immunostimulatory
[+]
Effects of bisphenol A on the proliferation, migration, and tumor growth of colon cancer cells.
Nov 03, 2021
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2021 Nov 4 ;158:112662. Epub 2021 Nov 4. PMID:
34743013
Article Published Date
: Nov 03, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Colon Cancer
Problem Substances
:
Bisphenol A
[+]
Effects of oral bovine lactoferrin on a mouse model of inflammation associated colon cancer.
Sep 08, 2020
Click here to read the entire abstract
Pubmed Data
: Biochem Cell Biol. 2020 Sep 9. Epub 2020 Sep 9. PMID:
32905707
Article Published Date
: Sep 08, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Colon Cancer
,
Gastrointestinal Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
[+]
EGCG modulates the reversal of gene silencing involved in colon carcinogenesis.
May 05, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 6. Epub 2016 May 6. PMID:
27167203
Article Published Date
: May 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Dose Response
,
Epigenetic Modification In Cancer
,
Gene Expression Regulation
[+]
Egpytian flaxseed oil has chemopreventive properties against rat colon carcinogenesis.
Dec 31, 2010
Click here to read the entire abstract
Pubmed Data
: Asian Pac J Cancer Prev. 2011 ;12(9):2385-92. PMID:
22296388
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed Oil
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
[+]
Ellagic acid ameliorates cisplatin induced hepatotoxicity in colon carcinogenesis.
Apr 04, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2019 Apr 5. Epub 2019 Apr 5. PMID:
30953405
Article Published Date
: Apr 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Chemoprotective Agents
[+]
Epigenetics/epigenomics and prevention by curcumin of early stages of inflammatory-driven colon cancer.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2020 Feb ;59(2):227-236. Epub 2019 Dec 9. PMID:
31820492
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colon Cancer
,
Gastrointestinal Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
Ergosterol peroxide down-regulated β-catenin signaling, which exerted anti-proliferative and pro-apoptotic activities in CRC cells.
Sep 14, 2015
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2015 Sep 15 ;173:303-12. Epub 2015 Jul 22. PMID:
26210065
Article Published Date
: Sep 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
[+]
Eriodictyol can be used as an effective chemopreventive agent against DMH-induced colon carcinogenesis.
Aug 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Res (Camb). 2017 Sep 1 ;6(5):678-692. Epub 2017 Jun 19. PMID:
30090535
Article Published Date
: Aug 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Eriodictyol
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Extracts of Neem leaf were effective in inducing apoptosis in leukemia and colon cancer cells.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharm Pharm Sci. 2015 Nov ;18(4):729-46. PMID:
26626256
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Neem
Diseases
:
Acute T cell Leukemias
,
Colon Cancer
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Plant Extracts
,
Selective Cytotoxicity
[+]
Extravirgin olive oil up-regulates CB₁ tumor suppressor gene in human colon cancer cells.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Mar ;26(3):250-8. Epub 2014 Dec 3. PMID:
25533906
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Olive Oil
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Cannabinoid Receptors
,
Endocannabinoid System
,
Epigenetic Modification In Cancer
,
Plant Extracts
[+]
Fermented miso prevents the induction of colonic aberrant crypt foci associated with colon carcinogenesis.
Feb 17, 2006
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2006 Feb 17;340(3):800-6. Epub 2005 Dec 20. PMID:
11748458
Article Published Date
: Feb 17, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Miso
,
Soy
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Fucoidan is a candidate anti-tumor functional food against colon cancer.
Sep 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2012 Oct ;10(10):2337-48. Epub 2012 Oct 22. PMID:
23170088
Article Published Date
: Sep 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Tumor
[+]
Fucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2019 Feb ;64:198-205. Epub 2018 Oct 25. PMID:
30530259
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Fucoxanthin, lutein and tetrahydrocurcumin may have chemopreventive effects against colon carcinogenesis.
Jan 01, 1998
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 1998 Jan;19(1):81-5. PMID:
9472697
Article Published Date
: Jan 01, 1998
Study Type
: Animal Study
Additional Links
Substances
:
Carotenoids
,
Curcumin
,
Fucoxanthin
,
Lutein
,
Tetrahydrocurcumin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
[+]
Gac fruit extract inhibits colon tumor growth.
Apr 01, 2005
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2005 Apr;26(4):881-9. PMID:
15753981
Article Published Date
: Apr 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Gac
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
Additional Keywords
:
Plant Extracts
[+]
Gamma and delta tocopherols supplementation at 0.2% in diet significantly inhibited PhIP-induced and colitis-promoted colon carcinogenesis.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Carcinog. 2017 Jan ;56(1):172-183. Epub 2016 May 13. PMID:
27175800
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Colon Cancer
,
DNA damage
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Gamma-tocopherol may play a significant role in preventing colon cancer.
Dec 31, 2001
Click here to read the entire abstract
Pubmed Data
: Cancer Detect Prev. 2002 ;26(1):78-84. PMID:
12088207
Article Published Date
: Dec 31, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E: Gamma-Tocopherol
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
[+]
Genistein regulates tumor microenvironment and exhibits anticancer effects in experimental colon carcinogenesis model.
Jun 02, 2016
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2016 Jun 3. Epub 2016 Jun 3. PMID:
27255553
Article Published Date
: Jun 02, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Heme oxygenase-1 inducer
,
NF-E2-Related Factor-2 (Nrf2) Modulator
Additional Keywords
:
Cancer Stem Cells
,
Tumor Microenvironment
[+]
Germinated brown rice can be a promising dietary supplement in prevention of colon cancer.
Mar 25, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2010 Mar 26 ;9:16. Epub 2010 Mar 26. PMID:
20346115
Article Published Date
: Mar 25, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Brown Rice
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Ginger contains the compound zerumbone, which inhibits colon and lung carcinogenesis in mice.
Jan 15, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2009 Jan 15;124(2):264-71. PMID:
19003968
Article Published Date
: Jan 15, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Colon Cancer
,
Lung Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
[+]
Ginkgetin induces G2-phase arrest in HCT116 colon cancer cells.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2017 Oct ;51(4):1331-1342. Epub 2017 Sep 5. PMID:
28902363
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
[+]
Ginseng berry concentrate prevents colon cancer.
Mar 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Physiol Pharmacol. 2021 Apr ;72(2). Epub 2021 Aug 6. PMID:
34374659
Article Published Date
: Mar 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Chemopreventive
[+]
Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2016 Oct ;40(4):400-408. Epub 2016 Apr 5. PMID:
27746693
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Grape juice concentrate is able to exert some chemopreventive activity on rat colon carcinogenesis.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2015 Nov ;40(3):870-5. Epub 2015 Sep 28. PMID:
26492449
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Grape juice is able to modulate rat colon carcinogenesis as a result of induction of apoptosis.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Mech Methods. 2015 Feb ;25(2):91-7. Epub 2015 Jan 22. PMID:
25421551
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
Colon Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Apoptotic
,
Bcl-2 protein down-regulation
Additional Keywords
:
Phytotherapy
[+]
Grapefruit contains compounds which inhibit colon carcinogenesis.
Jun 01, 2006
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2006 Jun;27(6):1257-65. Epub 2005 Dec 29. PMID:
16387741
Article Published Date
: Jun 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Grapefruit
Diseases
:
Colon Cancer
[+]
Green vegetables (chlorophyll) prevent the cytotoxic and hyperproliferative effect of red meat (heme) in the rat colon
Feb 01, 2005
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis.2005 Feb;26(2):387-93. Epub 2004 Nov 18. PMID:
15550456
Article Published Date
: Feb 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Chlorophyll
,
Vegetables: All
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Gut microbiota promotes tumorigenesis by increasing the exposure of gut epithelium to carcinogens.
Apr 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Inflamm Bowel Dis. 2013 May ;19(6):1266-77. PMID:
23567778
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Colitis
,
Colon Cancer
,
Dysbiosis
Additional Keywords
:
Microbiota
,
Risk Factors
[+]
High temperature- and pressure-treated garlic inhibits chemically-induced precancerous cellular changes in the rat colon.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Asian Pac J Cancer Prev. 2009;10(5):827-31. PMID:
20104973
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
High-content hydrogen water can inhibit colon cancer, particularly in combination with 5-fluorouracil.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PeerJ. 2015 ;3:e859. Epub 2015 Apr 7. PMID:
25870767
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Water
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
[+]
High-fat Western diet-induced obesity contributes to increased tumor growth in mouse models of human colon cancer.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2016 Dec ;36(12):1325-1334. Epub 2016 Oct 20. PMID:
27866828
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
,
High Fat Diet
,
Inflammation
,
Insulin Resistance
,
Obesity
Anti Therapeutic Actions
:
Western Diet
[+]
Higher sugar-sweetened beverage intake was associated with a significantly increased risk of cancer recurrence in colon cancer patients.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(6):e99816. Epub 2014 Jun 17. PMID:
24937507
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Recurrence Risk
Problem Substances
:
Sugar Sweetened Beverages
[+]
Honokiol affects stem cell viability by suppressing oncogenic YAP1 function to inhibit colon tumorigenesis.
Jun 25, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cells. 2021 Jun 26 ;10(7). Epub 2021 Jun 26. PMID:
34206989
Article Published Date
: Jun 25, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Honokiol
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Honokiol induces ferroptosis in colon cancer cells by regulating GPX4 activity.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Am J Cancer Res. 2021 ;11(6):3039-3054. Epub 2021 Jun 15. PMID:
34249443
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Honokiol
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
[+]
Hydroalcoholic camu-camu seed extracts prevent chromosome damage and act as antioxidant and cytotoxic agents.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: Food Res Int. 2019 Nov ;125:108551. Epub 2019 Jul 12. PMID:
31554128
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Camu Camu
Diseases
:
Colon Cancer
,
Colorectal Cancer
,
DNA damage
,
Liver Cancer
,
Lung Cancer
Pharmacological Actions
:
Antimutagenic Agents
,
Antiproliferative
,
Chemoprotective Agents
,
Genoprotective
Additional Keywords
:
Plant Extracts
[+]
In vitro and in vivo antitumor activity of Yerba Mate extract in colon cancer models.
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2020 Jul ;85(7):2186-2197. Epub 2020 Jun 22. PMID:
32567699
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Yerba Santa
Diseases
:
Colon Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
,
Apoptotic
[+]
Inhibition effect of glycyrrhiza polysaccharide on tumor growth through regulation of the gut microbiota composition.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Sci. 2018 Aug ;137(4):324-332. Epub 2018 May 5. PMID:
30150145
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Glycyrrhiza uralensis
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Gastrointestinal Agents
Additional Keywords
:
Phytotherapy
,
Polysaccharides
[+]
Inhibition of azoxymethane-induced colon cancer by orange juice.
Dec 31, 1999
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2000 ;36(2):224-9. PMID:
10890034
Article Published Date
: Dec 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Orange
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Chemopreventive
Additional Keywords
:
Fruit Juice
,
Phytotherapy
[+]
Inhibitory effect of Thai purple rice husk extract on chemically induced carcinogenesis in rats.
Jan 11, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2021 Jan 12 ;26(2). Epub 2021 Jan 12. PMID:
33445792
Article Published Date
: Jan 11, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Rice
Diseases
:
Colon Cancer
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Inhibitory effects of apigenin on tumor carcinogenesis by altering the gut microbiota.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2020 ;2020:7141970. Epub 2020 Oct 6. PMID:
33082711
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apigenin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Inonotus obliquus polysaccharide may be a therapeutic drug candidate for colitis-associated cancer.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:621835. Epub 2021 Feb 2. PMID:
33603669
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Inositol hexaphosphate inhibits the cell cycle of human breast and colon cancer cells.
Jul 01, 2001
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2001 Jul-Aug;21(4A):2393-403. PMID:
11724298
Article Published Date
: Jul 01, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Inositol Hexaphosphate
Diseases
:
Breast Cancer
,
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Cell cycle arrest
[+]
Java plum fruit extract anthocyanins suppressed proliferation in HCT-116 cells and elevated apoptosis in both HCT-116 cells and colon CSCs.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2016 ;8(3). Epub 2016 Feb 26. PMID:
26927179
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Jambul
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Cancer Stem Cells
[+]
Kampo preparation Daikenchuto could be useful for cancer therapy.
Apr 07, 2016
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2016 Apr 8. Epub 2016 Apr 8. PMID:
27059786
Article Published Date
: Apr 07, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Ginseng
Diseases
:
Breast Cancer
,
Colon Cancer
,
Esophageal Cancer
,
Gastric Cancer
Pharmacological Actions
:
Apoptotic
[+]
Krill oil perturbs proliferation and migration of mouse colon cancer cells.
Sep 14, 2020
Click here to read the entire abstract
Pubmed Data
: Lipids. 2020 Sep 15. Epub 2020 Sep 15. PMID:
32931040
Article Published Date
: Sep 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Lack of chronic oral toxicity of chemopreventive bovine lactoferrin.
Mar 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2008 Apr-Jun;9(2):313-6. PMID:
18712982
Article Published Date
: Mar 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Safety of Natural Substances
[+]
Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis.
Apr 10, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Apr 11 ;8(15):24719-24727. PMID:
28445967
Article Published Date
: Apr 10, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus casei
,
Vitamin K2
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Lactobacillus fermentum V3 ameliorates colitis-associated tumorigenesis by modulating the gut microbiome.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Cancer Res. 2020 ;10(4):1170-1181. Epub 2020 Apr 1. PMID:
32368393
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus fermentum
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Gastrointestinal Agents
[+]
Lactobacillus rhamnosus enhances the immunological antitumor effect of 5-fluorouracil against colon cancer.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pak J Biol Sci. 2019 Jan ;22(12):597-606. PMID:
31930859
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus rhamnosus
Diseases
:
Colon Cancer
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
[+]
Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Oct ;83:536-541. Epub 2016 Jul 20. PMID:
27447122
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus rhamnosus
Diseases
:
Colon Cancer
,
Inflammation
Pharmacological Actions
:
Anticarcinogenic Agents
,
Apoptotic
,
Chemopreventive
[+]
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(7):e103298. Epub 2014 Jul 24. PMID:
25057912
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Colitis
,
Colon Cancer
,
Inflammation
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Lemongrass extract possesses potent anticancer activity against human colon cancers.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Cancer Ther. 2019 Jan-Dec;18:1534735419889150. PMID:
31845598
Article Published Date
: Dec 31, 2018
Study Type
: In Vitro Study, Transgenic Animal Study
Additional Links
Substances
:
Lemongrass
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Lentils might be protective against colon carcinogenesis and that hydrothermal treatment resulted in an improvement in the chemopreventive potential for the whole lentils.
May 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2009 May;29(5):355-62. PMID:
19555818
Article Published Date
: May 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Lentils
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Lentinan from shiitake mushrooms (Lentinus edodes) inhibits of human colon cancer cells.
Oct 01, 2002
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2002 Oct;8(5):581-9. PMID:
12470439
Article Published Date
: Oct 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Beta-glucan
,
Lentinan
,
Shiitake Mushroom
Diseases
:
Colon Cancer
Additional Keywords
:
Antineoplastic Agents
[+]
Licochalcone A inhibits proliferation and promotes apoptosis of colon cancer cell.
Mar 03, 2021
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2021 Mar 4 ;273:113989. Epub 2021 Mar 4. PMID:
33677006
Article Published Date
: Mar 03, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Licorice
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity.
Jun 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2008 Jul ;103(1):48-54. Epub 2008 Jul 1. PMID:
18484961
Article Published Date
: Jun 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Licorice
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antineoplastic Agents
,
Antioxidants
,
Antiproliferative
,
Chemoprotective Agents
[+]
Limonin might be a candidate chemopreventive agent against intestinal carcinogenesis.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Biochem Nutr. 2015 Jul ;57(1):39-43. Epub 2015 Jun 17. PMID:
26236099
Article Published Date
: Jun 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Limonoids
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Dose Response
[+]
Lion's mane has antitumor effects in tumor-bearing mice.
Sep 28, 2011
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2011 Sep 28 ;59(18):9861-9. Epub 2011 Aug 25. PMID:
21846141
Article Published Date
: Sep 28, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Colon Cancer
,
Low Immune Function: Natural Killer Cells
,
Tumors
Pharmacological Actions
:
5-Lipoxygenase Inhibitor
,
Anti-Angiogenic
,
Antineoplastic Agents
,
Cyclooxygenase 2 Inhibitors
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Liposomal formulation of galbanic acid improved therapeutic efficacy of pegylated liposomal doxorubicin in mouse colon carcinoma.
Jul 01, 2019
Click here to read the entire abstract
Pubmed Data
: Sci Rep. 2019 Jul 2 ;9(1):9527. Epub 2019 Jul 2. PMID:
31267009
Article Published Date
: Jul 01, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Live Lactobacillus casei ATCC393 exerts potent anti-proliferative, growth-inhibitory and pro-apoptotic effects in vitro.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(2):e0147960. Epub 2016 Feb 5. PMID:
26849051
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lactobacillus casei
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Long-term oral administration of piceatannol attenuates colon tumor growth induced by azoxymethane.
Oct 07, 2021
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2021 Oct 8:1-12. Epub 2021 Oct 8. PMID:
34622729
Article Published Date
: Oct 07, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Piceatannol
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Luteolin can be a chemotherapeutic agent against colorectal cancer.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2014 Nov ;33(11):1176-85. Epub 2014 Feb 14. PMID:
24532706
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Luteolin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Magnesium improves cisplatin-mediated tumor killing while protecting against cisplatin-induced nephrotoxicity.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Renal Physiol. 2017 Aug 1 ;313(2):F339-F350. Epub 2017 Apr 19. PMID:
28424213
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Magnesium
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Colon Cancer
,
Magnesium Deficiency
Pharmacological Actions
:
Antiproliferative
,
Chemoprotective Agents
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
[+]
Maitake (G. frondosa) exhibits antitumor activity in colon tumor-bearing mice.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Feb;13(1):20-30. PMID:
20136432
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Maitake Mushroom
Diseases
:
Colon Cancer
Pharmacological Actions
:
Interferon-gamma (IFN-gamma) inducer
,
Interleukin-12 upregulation
[+]
Mangiferin inhibits bowel carcinogenesis in male rats.
Feb 26, 2001
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2001 Feb 26;163(2):163-70. PMID:
11165750
Article Published Date
: Feb 26, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Mangiferin
Diseases
:
Colon Cancer
,
Colon Polyps
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Xanthones
[+]
Modified Citrus Pectin inhibits liver metastasis of colon cancer.
Dec 28, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Dec 28;14(48):7386-91. PMID:
19109874
Article Published Date
: Dec 28, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Modified Citrus Pectin
Diseases
:
Colon Cancer
Additional Keywords
:
Liver Metastasis
[+]
Morin targets NF-κB and acts as a potent anti-inflammatory and pro-apoptotic agent for colon cancer prevention.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Apr ;100:367-373. Epub 2018 Feb 16. PMID:
29453046
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Guava
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Moringa oleifera leaves induced antioxidant and phase II enzymes in a colitis-associated colon carcinogenesis.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID:
31224959
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Chemopreventive
,
Phase II Detoxification Enzyme Inducer
[+]
Mustard seed oil is more effective in preventing colon cancer in rats than dietary fish oil.
Jun 30, 2003
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2003 Jun 30;196(1):29-34. PMID:
12860286
Article Published Date
: Jun 30, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Mustard Seeds
Diseases
:
Colon Cancer
Additional Keywords
:
Omega 3/6 Ratio
,
Omega 6 Fatty Acids are Detrimental
[+]
Myricetin could be used preventatively to reduce the risk of developing colon cancers.
Aug 05, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Aug 6. Epub 2016 Aug 6. PMID:
27507058
Article Published Date
: Aug 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Myricetin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
N. sativa administration exerts potent inhibitory effects on rat tumor development and on cellular proliferation in multiple organ sites.
Aug 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2010 Sep ;1(5):913-924. Epub 2010 Sep 1. PMID:
22966405
Article Published Date
: Aug 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Colon Cancer
,
Lung Cancer
,
Stomach Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Naringin combined with tunicamycin+BAY 11-7082 efficiently induced apoptotic cell death in HT29 colon cancer cells.
Sep 25, 2020
Click here to read the entire abstract
Pubmed Data
: Biochem Genet. 2020 Sep 26. Epub 2020 Sep 26. PMID:
32979141
Article Published Date
: Sep 25, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Citrus naringin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
[+]
Nexrutine could be useful candidate agent for colon cancer chemoprevention and treatment.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2016 Aug ;55(8):1262-74. Epub 2015 Aug 10. PMID:
26259065
Article Published Date
: Jul 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Nexrutine (Phellodendrom)
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
[+]
Nigella sativa has a protective roll against the initiation of colon carcinogenesis.
Sep 30, 2008
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2008 Oct ;22(10):1311-23. PMID:
18570215
Article Published Date
: Sep 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Selenium
,
Thymoquinone
,
Vitamin A
Diseases
:
Colon Cancer
,
DNA damage
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
Additional Keywords
:
Plant Extracts
[+]
Nobiletin and its colonic metabolites suppress colitis-associated colon carcinogenesis.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2017 Apr ;42:17-25. Epub 2017 Jan 11. PMID:
28107678
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Nobiletin
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Chemopreventive
,
Heme oxygenase-1 inducer
[+]
Nutmeg effectively inhibits cancer growth and metabolism by inhibiting the activity of lactate dehydrogenase (LDH).
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2016 ;44(5):1063-79. Epub 2016 Jul 19. PMID:
27430914
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Nutmeg
Diseases
:
Colon Cancer
,
Lung Cancer
Pharmacological Actions
:
Lactate Dehydrogenase A Inhibitor
Additional Keywords
:
Plant Extracts
,
Warburg Effect
[+]
Oleuropein-rich leaf extract as a broad inhibitor of tumour and macrophage iNOS in an Apc mutant rat model.
Oct 05, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2021 Oct 6 ;10(10). Epub 2021 Oct 6. PMID:
34679712
Article Published Date
: Oct 05, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Tumor Microenvironment
[+]
Oligonol is effective in protecting against DSS-induced mouse colitis and colon carcinogenesis.
Jul 09, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxid Redox Signal. 2013 Jul 10 ;19(2):102-14. Epub 2013 May 15. PMID:
23394584
Article Published Date
: Jul 09, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Lychee
Diseases
:
Colitis
,
Colon Cancer
,
Inflammation
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Colitis
,
COLON CANCER
,
Inflammation
,
Lipid Peroxidation
,
Lychee
,
oxidative stress
[+]
Oolong tea may be a good chemopreventive agent for colon cancer.
Apr 01, 2006
Click here to read the entire abstract
Pubmed Data
: Cancer Sci. 2006 Apr;97(4):248-51. PMID:
16630115
Article Published Date
: Apr 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Oolong tea
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
[+]
Oral administration of dandelion root extract inhibited the growth of human colon xenograft models by more than 90%.
Aug 21, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Aug 22. Epub 2016 Aug 22. PMID:
27564258
Article Published Date
: Aug 21, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Dandelion
Diseases
:
Colon Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
,
Plant Extracts
,
Selective Cytotoxicity
[+]
Oral administration of nobiletin significantly inhibited colitis-associated colon carcinogenesis in mice.
Sep 09, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2015 Sep 10. Epub 2015 Sep 10. PMID:
26445322
Article Published Date
: Sep 09, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nobiletin
Diseases
:
Colitis
,
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Metabolites
[+]
Orally administered glycolipid fraction from spinach could suppress colon tumor growth in mice.
Jul 31, 2008
Click here to read the entire abstract
Pubmed Data
: Lipids. 2008 Aug ;43(8):741-8. Epub 2008 Jul 2. PMID:
18594894
Article Published Date
: Jul 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Spinach
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
[+]
Orthosiphon stamineus extract inhibits growth of colon tumors.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2012 ;64(1):89-99. Epub 2011 Dec 2. PMID:
22136553
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Orthosiphon
Diseases
:
Colon Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Our results indicate that berberine can be a potential chemoprevention and chemotherapy agent for human colon cancer by targeting Wnt/β-catenin signaling.
Apr 01, 2012
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2012 Apr 2. Epub 2012 Apr 2. PMID:
22469784
Article Published Date
: Apr 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Colon Cancer
Pharmacological Actions
:
Wnt/β-catenin pathway down-regulation
[+]
Oyster mushroom (P. osteatus) significantly reduces tumor formation in a rat model of colon cancer.
May 01, 2007
Click here to read the entire abstract
Pubmed Data
: World J Surg. 2007 May;31(5):1041-6. PMID:
9538185
Article Published Date
: May 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Oyster Mushroom
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Physical activity can directly counteract tumor cell growth.
Jun 12, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Transl Myol. 2016 Jun 13 ;26(2):5958. Epub 2016 Jun 13. PMID:
27478560
Article Published Date
: Jun 12, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antiproliferative
[+]
Pinostilbene is a major colonic metabolite of pterostilbene which significantly inhibited the growth of human colon cancer cells.
Mar 17, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2016 Mar 18. Epub 2016 Mar 18. PMID:
26990242
Article Published Date
: Mar 17, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Blueberry
,
Pterostilbene
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
[+]
Piperlongumine may be an effective chemopreventive agent for colon cancer.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Jan ;109:1462-1477. Epub 2018 Nov 13. PMID:
30551398
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Piperlongumine
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
[+]
Polyphenols from oleaster leaves might have a strong potential as chemopreventive agent in colorectal cancer.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(2):e0170823. Epub 2017 Feb 17. PMID:
28212423
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study, In Vitro Study
