Cystic Fibrosis

Name	AC	CK
Vitamin D	8	71
Omega-3 Fatty Acids	7	54
Lactobacillus rhamnosus GG	4	31
NAC (N-acetyl-L-cysteine)	4	31
Vitamin E	3	30
Probiotics	5	23
DHA (Docosahexaenoic Acid)	4	22
Glutathione	4	22
Vitamin C	4	22
Antioxidant formulas	2	20
Arginine	2	20
Coenzyme Q10	2	20
Salt	2	20
Taurine	2	20
Ursodeoxycholic acid	2	20
Whey	2	20
Zinc	2	20
beta-Carotene	2	20
Curcumin	9	19
Lactoferrin	3	13
EPA (Eicosapentaenoic Acid)	2	12
Manuka Honey	2	11
Carotenoids	1	10
Choline	1	10
EGCG (Epigallocatechin gallate)	1	10
Flaxseed	1	10
Folic Acid	1	10
Gamma-Linoleic Acid (GLA)	1	10
Honey	1	10
Lactobacillus reuteri	1	10
Lignans	1	10
Lipase	1	10
Magnesium	1	10
Pancreatic Enzymes	1	10
Selenium	1	10
Sulforaphane	1	10
Vitamin A	1	10
Vitamin B-12	1	10
Vitamin K	1	10
Genistein	7	7
Flavonoids	3	4
Resveratrol	2	3
Feverfew	1	2
St. Johns Wort	1	2
Amla Fruit	1	1
Bergamot orange	1	1
Breast Milk	1	1
Caffeic acid phenethyl ester	1	1
Cayenne	1	1
Coleus Forskohlii	1	1
Cordyceps sinensis	1	1
Curcuminoids	1	1
Docosahexaenoic acid (DHA)	1	1
Evening Primrose Oil	1	1
Fish Oil	1	1
Ginseng (Korean)	1	1
Isoflavones	1	1
Lactobacillus rhamnosus	1	1
Olive leaf extract	1	1
Sodium Bicarbonate	1	1
Trichilia rubescens	1	1
Enzyme Therapy	1	0

Name	AC	CK
Antibiotics	1	10
Bisphosphonates	1	10
Corticosteroid	1	10
Hydrocortisone	1	10
Potato	1	10
Prednisone	1	10
Proton-Pump Inhibitors	1	10

Name	AC	CK
Acupuncture	1	10
Exercise	1	10
Exercise: Inspiratory Muscle Training	1	10
Massage/Therapeutic Touch	1	10
Music	1	10
Physical Therapy	1	10
Spiritual/Religious Practice	1	10
Whole-Body Vibration	1	10
Yoga	1	10
Breastfeeding	1	1

Name	AC	CK	Focus
Vaccination: Influenza	2	30
Vaccination: All	1	10

[+]

There is currently no evidence from randomised studies that influenza vaccine given to people with cystic fibrosis is of benefit to them. Oct 07, 2009

Click here to read the entire abstract

Pubmed Data : Cochrane Database Syst Rev. 2009 Oct 7;(4):CD001753. PMID: 19821281

Article Published Date : Oct 07, 2009

Study Type : Meta Analysis

Additional Links

Diseases : Cystic Fibrosis

Additional Keywords : Vaccine Research

Anti Therapeutic Actions : Vaccination: Influenza

[+]

Gut Bifidobacteria enrichment following oral Lactobacillus-supplementation is associated with clinical improvements in children with cystic fibrosis.Jul 27, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Pulm Med. 2022 Jul 28 ;22(1):287. Epub 2022 Jul 28. PMID: 35902830

Article Published Date : Jul 27, 2022

Study Type : Human Study

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Medication Reduction

[+]

5-methyltehydrofolate (folic acid) and vitamin B12 ameliorate red blood cell abnormalities in pediatric patients with Cystic Fibrosis. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : PLoS One. 2009;4(3):e4782. Epub 2009 Mar 11. PMID: 19277125

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : Folic Acid , Vitamin B-12

Diseases : Cystic Fibrosis

[+]

A high lipase pancreatic enzyme is superior to regular pancreatin in adult cystic fibrosis patients. Dec 01, 1994

Click here to read the entire abstract

Pubmed Data : Aliment Pharmacol Ther. 1994 Dec;8(6):603-7. PMID: 7696449

Article Published Date : Dec 01, 1994

Study Type : Human Study

Additional Links

Substances : Lipase, Pancreatic Enzymes

Diseases : Cystic Fibrosis

[+]

Acupuncture is effective for managing symptoms and illnesses associated with cystic fibrosis. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2005;33(1):151-6. PMID: 15844843

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Therapeutic Actions : Acupuncture

[+]

An 8-month treatment with omega-3 fatty acids (EPA and DHA) has a positive effects, such as decreasing inflammation, in patients with cystic fibrosis. Jan 01, 2003

Click here to read the entire abstract

Pubmed Data : JPEN J Parenter Enteral Nutr. 2003 Jan-Feb;27(1):52-7. PMID: 12549599

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid)

Diseases : Cystic Fibrosis

[+]

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2008 Jan;7(1):60-7. Epub 2007 Jun 13. PMID: 17569601

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas, Carotenoids, Coenzyme Q10, Vitamin E

Diseases : Cystic Fibrosis

Pharmacological Actions : Antioxidants

[+]

Annual influenza vaccination hampers the development of virus-specific CD8(+) T cell responses necessary to protect against influenza infection. Nov 01, 2011

Click here to read the entire abstract

Pubmed Data : J Virol. 2011 Nov ;85(22):11995-2000. Epub 2011 Aug 31. PMID: 21880755

Article Published Date : Nov 01, 2011

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis, Influenza

Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza

Adverse Pharmacological Actions : Immunosuppressive

[+]

Antioxidant supplementation may have therapeutic value in the treatment of cystic fibrosis - Article 2. Jan 01, 2003

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2003 Jan;77(1):150-9. PMID: 12499335

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Substances : beta-Carotene, Selenium

Diseases : Cystic Fibrosis

[+]

Antioxidant supplementation may have therapeutic value in the treatment of cystic fibrosis - Article 2. Apr 01, 1994

Click here to read the entire abstract

Pubmed Data : Acta Paediatr Suppl. 1994 Apr;83(395):49-57. PMID: 8025360

Article Published Date : Apr 01, 1994

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas

Diseases : Cystic Fibrosis

[+]

Beta-carotene supplementation ameliorates deficiencies and reduces oxidative stress in Cystic Fibrosis patients. Jan 01, 2000

Click here to read the entire abstract

Pubmed Data : Ann Nutr Metab. 2000;44(1):30-7. PMID: 10838464

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : beta-Carotene

Diseases : Cystic Fibrosis

Pharmacological Actions : Antioxidants

[+]

Bisphosphonates used for osteoporosis in patients with cystic fibrosis increases bone mineral density without increasing bone quality/strength, while causing bone pain and flu-like symptoms. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Cochrane Database Syst Rev. 2009(4):CD002010. Epub 2009 Oct 7. PMID: 19821288

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis, Osteoporosis

Problem Substances : Bisphosphonates

[+]

Bolus weekly vitamin D3 supplementation impacts gut and airway microbiota in adults with cystic fibrosis.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Endocrinol Metab. 2018 02 1 ;103(2):564-574. PMID: 29161417

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Cystic Fibrosis, Inflammation, Vitamin D Deficiency

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Microbiota

[+]

Candida albicans chronic colonisation in cystic fibrosis may be associated with inhaled antibiotics.Jun 30, 2015

Click here to read the entire abstract

Pubmed Data : Mycoses. 2015 Jul ;58(7):416-21. Epub 2015 Jun 9. PMID: 26058475

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Diseases : Candida Infection , Cystic Fibrosis, Cystic Fibrosis: Infections

Problem Substances : Antibiotics

[+]

Choline-related supplements may improve status of children with Cystic FibrosisMar 01, 2007

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2007 Mar;85(3):702-8. PMID: 17344490

Article Published Date : Mar 01, 2007

Study Type : Human Study

Additional Links

Substances : Choline

Diseases : Cystic Fibrosis

[+]

Coenzyme Q10 levels are low in children with cystic fibrosis, indicating that supplementation could be beneficial. Apr 01, 2002

Click here to read the entire abstract

Pubmed Data : Pharmacol Res. 2002 Apr;45(4):355-9. PMID: 18534204

Article Published Date : Apr 01, 2002

Study Type : Human Study

Additional Links

Substances : Coenzyme Q10

Diseases : Cystic Fibrosis

[+]

Corticosteroids contribute to muscle weakness in Cystic Fibrosis patients. Oct 01, 2003

Click here to read the entire abstract

Pubmed Data : J Appl Physiol. 2003 Oct;95(4):1379-84. Epub 2003 Jun 13. PMID: 12807896

Article Published Date : Oct 01, 2003

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Problem Substances : Corticosteroid, Hydrocortisone, Prednisone

[+]

Cysteamine plus epigallocatechin gallate can be used for autophagy-dependent rescue of class II-mutated CFTR.Mar 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Death Differ. 2016 Apr 1. Epub 2016 Apr 1. PMID: 27035618

Article Published Date : Mar 31, 2016

Study Type : Animal Study, Human Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation

[+]

Daily vitamin D supplementation was associated with reduced Aspergillus induced IL-13 responses.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asthma Res Pract. 2015;1. Epub 2015 Jun 4. PMID: 27011794

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Aspergillosis, Cystic Fibrosis, Cystic Fibrosis: Infections, Vitamin D Deficiency

Pharmacological Actions : interleukin-13 down-regulation

[+]

Engaged spirituality supports pro-adherence determinants and behaviour in patients with cystic fibrosis.Mar 31, 2016

Click here to read the entire abstract

Pubmed Data : J Pediatr Psychol. 2016 Apr 1. Epub 2016 Apr 1. PMID: 27037417

Article Published Date : Mar 31, 2016

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Therapeutic Actions : Spiritual/Religious Practice

[+]

Exposure to Proton pump inhibitors is associated with higher numbers of hospitalizations for pulmonary exacerbation in cystic fibrosis patients.Sep 30, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Gastroenterology Res. 2017 Oct ;10(5):288-293. Epub 2017 Oct 26. PMID: 29118869

Article Published Date : Sep 30, 2017

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Additional Keywords : Increased Risk

Problem Substances : Proton-Pump Inhibitors

[+]

Flaxseed modulates inflammatory and oxidative stress biomarkers in cystic fibrosis.May 12, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2015 May 13 ;15:148. Epub 2015 May 13. PMID: 25963404

Article Published Date : May 12, 2015

Study Type : Human Study

Additional Links

Substances : Flaxseed, Lignans, Omega-3 Fatty Acids

Diseases : Cystic Fibrosis, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Fractional exhalation nitric oxide changes in cystic fibrosis patients induced by compound honey syrup.Dec 04, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Pulm Med. 2023 Dec 5 ;23(1):488. Epub 2023 Dec 5. PMID: 38053097

Article Published Date : Dec 04, 2023

Study Type : Human Study

Additional Links

Substances : Honey

Diseases : Cystic Fibrosis

[+]

Glutathione improves clinical markers in cystic fibrosis patients. Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2008 Sep;7(5):433-6. Epub 2008 May 21. PMID: 18499536

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Glutathione

Diseases : Cystic Fibrosis

[+]

High dose vitamin K is efficacious in correcting vitamin K deficiency in cystic fibrosis. Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2008 Sep;7(5):457-9. Epub 2008 May 29. PMID: 18511355

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Vitamin K

Diseases : Cystic Fibrosis

Additional Keywords : Pancreatic Insufficiency

[+]

Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein.Dec 01, 2003

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2003 Dec;2(4):195-8. PMID: 15463873

Article Published Date : Dec 01, 2003

Study Type : Human Study

Additional Links

Substances : Whey

Diseases : Cystic Fibrosis, Lung Diseases, Oxidative Stress

Pharmacological Actions : Antioxidants, Glutathione Upregulation

[+]

Inhaled glutathione improves symptoms in patients with cystic fibrosis. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Chest. 2005 Jan;127(1):308-17. PMID: 15653998

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Substances : Glutathione

Diseases : Cystic Fibrosis

[+]

Inhaled hypertonic saline accelerates mucus clearance and improves lung function in patients with cystic fibrosis. Jan 19, 2006

Click here to read the entire abstract

Pubmed Data : N Engl J Med. 2006 Jan 19;354(3):241-50. PMID: 16421365

Article Published Date : Jan 19, 2006

Study Type : Human Study

Additional Links

Substances : Salt

Diseases : Cystic Fibrosis

[+]

Inhaled hypertonic saline significantly reduces the incidence of pulmonary exacerbations in patients with cystic fibrosis. Jan 19, 2006

Click here to read the entire abstract

Pubmed Data : N Engl J Med. 2006 Jan 19;354(3):229-40. PMID: 16421364

Article Published Date : Jan 19, 2006

Study Type : Human Study

Additional Links

Substances : Salt

Diseases : Cystic Fibrosis

[+]

Inspiratory muscle training is associated with significant improvements in physical endurance and strength in patients with Cystic Fibrosis. Nov 01, 2005

Click here to read the entire abstract

Pubmed Data : Respir Med. 2005 Nov;99(11):1440-58. PMID: 15894478

Article Published Date : Nov 01, 2005

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Therapeutic Actions : Exercise: Inspiratory Muscle Training

[+]

L-arginine improves exhaled nitric oxide and pulmonary function in patients with cystic fibrosis. Jul 15, 2006

Click here to read the entire abstract

Pubmed Data : Am J Respir Crit Care Med. 2006 Jul 15;174(2):208-12. Epub 2006 Apr 20. PMID: 16627863

Article Published Date : Jul 15, 2006

Study Type : Human Study

Additional Links

Substances : Arginine

Diseases : Cystic Fibrosis

[+]

L-arginine supplementation improve nitric oxide formation in cystic fibrosis patients who exhibit decreased levels of exhaled nitric oxide. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Eur Respir J. 2005 Jan;25(1):62-8. PMID: 15640324

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Substances : Arginine

Diseases : Cystic Fibrosis

[+]

L-ascorbate may offer potential as a therapeutic agent for the improvement of chronic rhinosinusitis in patients with cystic fibrosis. May 01, 2009

Click here to read the entire abstract

Pubmed Data : Am J Rhinol Allergy. 2009 May-Jun;23(3):294-9. PMID: 19490804

Article Published Date : May 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Cystic Fibrosis, Rhinosinusitis

[+]

Lactobacillus GG supplementation reduces pulmonary exacerberations and hospital admissions in patients with cystic fibrosis. Jul 01, 2009

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Jul;29(7):639-41. PMID: 17360077

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Cystic Fibrosis

[+]

Listening to motivational music while walking elicits more positive affective response in patients with cystic fibrosis.Apr 30, 2016

Click here to read the entire abstract

Pubmed Data : Complement Ther Clin Pract. 2016 May ;23:52-8. Epub 2016 Mar 16. PMID: 27157959

Article Published Date : Apr 30, 2016

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Therapeutic Actions : Exercise, Music

[+]

Manuka honey versus saline sinus irrigation in the treatment of cystic fibrosis-associated chronic rhinosinusitis.Aug 26, 2020

Click here to read the entire abstract

Pubmed Data : Clin Otolaryngol. 2020 Aug 27. Epub 2020 Aug 27. PMID: 32852889

Article Published Date : Aug 26, 2020

Study Type : Human Study

Additional Links

Substances : Manuka Honey

Diseases : Cystic Fibrosis, Rhinosinusitis

[+]

N-acetylcysteine increases the fluidity of airway mucus in patients with Cystic Fibrosis. Oct 01, 2004

Click here to read the entire abstract

Pubmed Data : : J Cell Physiol. 2004 Oct;201(1):106-16. PMID: 15281093

Article Published Date : Oct 01, 2004

Study Type : Human Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Cystic Fibrosis

Pharmacological Actions : Mucolytic

[+]

N-acetylcysteine reduces inflammation in patients with cystic fibrosis. Mar 21, 2006

Click here to read the entire abstract

Pubmed Data : Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4628-33. Epub 2006 Mar 13. PMID: 16537378

Article Published Date : Mar 21, 2006

Study Type : Human Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Cystic Fibrosis

[+]

Omega-3 and gamma-linolenic fatty acids improve pulmonary status (lung function, respiratory exacerbations and antibiotic consumption), inflammatory and anthropometric parameters in adults with CF.Dec 30, 2009

Click here to read the entire abstract

Pubmed Data : Arch Bronconeumol. 2009 Dec 30. Epub 2009 Dec 30. PMID: 20045240

Article Published Date : Dec 30, 2009

Study Type : Human Study

Additional Links

Substances : Gamma-Linoleic Acid (GLA) , Omega-3 Fatty Acids

Diseases : Cystic Fibrosis

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Drug Sparing

[+]

Omega-3 fatty acid supplementation reduces inflammatory biomarkers, erythrocyte sedimentation rate, and interleukin-8 concentrations in cystic fibrosis patients.May 01, 2010

Click here to read the entire abstract

Pubmed Data : J Pediatr Gastroenterol Nutr. 2010 May;50(5):537-44. PMID: 20639712

Article Published Date : May 01, 2010

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Cystic Fibrosis

Pharmacological Actions : Interleukin-8 downregulation

[+]

Omega-3 supplementation offers several clinical benefits as to the number of exacerbations and duration of antibiotic therapy in CF patients.Apr 30, 2016

Click here to read the entire abstract

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2016 May ;108:45-50. Epub 2016 Mar 28. PMID: 27154364

Article Published Date : Apr 30, 2016

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Cystic Fibrosis

[+]

Oral DHA shifts the phospholipid fatty acid profile in patients with cystic fibrosis to a less pro-inflammatory profile. Feb 01, 2008

Click here to read the entire abstract

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2008 Feb;78(2):109-15. Epub 2008 Feb 13. PMID: 18276127

Article Published Date : Feb 01, 2008

Study Type : Human Study

Additional Links

Substances : DHA (Docosahexaenoic Acid)

Diseases : Cystic Fibrosis

[+]

Oral magnesium supplementation may help overcome the failure of rhDNase-I in patients with cystic fibrosis. Nov 01, 2006

Click here to read the entire abstract

Pubmed Data : Thorax. 2006 Nov;61(11):962-8. PMID: 17071834

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Cystic Fibrosis

[+]

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Immunol. 2009 Mar;130(3):244-51. Epub 2008 Nov 22. PMID: 19028145

Article Published Date : Mar 01, 2009

Study Type : Human Study

Additional Links

Substances : Sulforaphane

Diseases : COPD, Cystic Fibrosis, Glutathione Deficiency , Lung Diseases, Pulmonary Fibrosis, Respiratory Diseases

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Phase II Detoxification Enzyme Inducer

Additional Keywords : Isothiocyanates

[+]

Oral supplementation with pressurized whey improves nutritional status and can have additional beneficial effects on inflammation in patients with cystic fibrosis.Feb 01, 2010

Click here to read the entire abstract

Pubmed Data : J Med Food. 2010 Feb;13(1):77-82. PMID: 20136439

Article Published Date : Feb 01, 2010

Study Type : Human Study

Additional Links

Substances : Whey

Diseases : C-Reactive Protein, Cystic Fibrosis, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation

[+]

Physical theray and massage reduces pain and improves the ease of breathing in adults with cystic fibrosis. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2009 Jan;8(1):79-81. Epub 2008 Aug 20. PMID: 18718820

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Therapeutic Actions : Massage/Therapeutic Touch, Physical Therapy

[+]

Potato crisp consumption without pancreatic enzyme supplementation has been reported to cause distal intestinal obstruction in patients with cystic fibrosis.Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : Eur J Pediatr. 2007 Sep;166(9):969-70. Epub 2006 Nov 24. PMID: 17124589

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Problem Substances : Potato

[+]

Probiotics improve the intestinal function of patients with cystic fibrosis. Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : An Pediatr (Barc). 2008 Dec;69(6):501-5. PMID: 19128761

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Cystic Fibrosis

[+]

Probiotics may improve respiratory and gastrointestinal outcomes in a stable cystic fibrosis population.Sep 28, 2016

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2016 Sep 29. Epub 2016 Aug 29. PMID: 27693010

Article Published Date : Sep 28, 2016

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Cystic Fibrosis

Pharmacological Actions : Gastrointestinal Agents

[+]

Probiotics might ameliorate the dysbiosis of cystis fibrosis gut microbiota.Nov 30, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cyst Fibros. 2014 Dec ;13(6):716-22. Epub 2014 Mar 11. PMID: 24636808

Article Published Date : Nov 30, 2014

Study Type : Human Study

Additional Links

Substances : Lactobacillus reuteri

Diseases : Cystic Fibrosis, Dysbiosis

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

[+]

Significantly altered gut microbiota, including reduced microbial diversity was seen in cystic fibrosis patients compared to healthy controls.Mar 08, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Microbiol. 2017 Mar 9 ;17(1):58. Epub 2017 Mar 9. PMID: 28279152

Article Published Date : Mar 08, 2017

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis, Dysbiosis

Additional Keywords : Microbiota, Risk Factors

[+]

Silibinins and curcumin as promising ligands against mutant cystic fibrosis transmembrane regulator protein.Jul 22, 2024

Click here to read the entire abstract

Pubmed Data : AMB Express. 2024 Jul 23 ;14(1):84. Epub 2024 Jul 23. PMID: 39043981

Article Published Date : Jul 22, 2024

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Cystic Fibrosis

[+]

Taurine may be a useful adjunct in patients with cystic fibrosis and severe steatorrhea.Dec 01, 1991

Click here to read the entire abstract

Pubmed Data : Am J Dis Child. 1991 Dec;145(12):1401-4. PMID: 1669669

Article Published Date : Dec 01, 1991

Study Type : Human Study

Additional Links

Substances : Taurine

Diseases : Cystic Fibrosis, Steatorrhea

[+]

The inability of patients with cystic fibrosis to produce adequate lactoferrin contributes to the pathogenesis of P. aeruginosa lung infection.Oct 01, 2004

Click here to read the entire abstract

Pubmed Data : J Infect Dis. 2004 Oct 1;190(7):1245-53. Epub 2004 Aug 26. PMID: 15346334

Article Published Date : Oct 01, 2004

Study Type : Human Study

Additional Links

Substances : Lactoferrin

Diseases : Cystic Fibrosis, Pseudomonas aeruginosa

[+]

The omega-3 fatty acids decrease serum leukotriene B4 in patients with cystic fibrosis. Oct 01, 1994

Click here to read the entire abstract

Pubmed Data : Pediatr Pulmonol. 1994 Oct;18(4):211-7. PMID: 7838619

Article Published Date : Oct 01, 1994

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Cystic Fibrosis

Pharmacological Actions : Leukotriene B4 downregulation

[+]

The probiotic Lactobacillus GG reduces intestinal inflammation in patients with cystic fibrosis. Apr 01, 2006

Click here to read the entire abstract

Pubmed Data : Br J Sports Med. 2006 Apr;40(4):351-4. PMID: 15379842

Article Published Date : Apr 01, 2006

Study Type : Human Study

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Cystic Fibrosis

[+]

There is a different microbiome gene repertoire in the airways of cystic fibrosis patients with severe lung disease.Jul 28, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2017 Jul 29 ;18(8). Epub 2017 Jul 29. PMID: 28758937

Article Published Date : Jul 28, 2017

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis, Lung Diseases

Additional Keywords : Microbiota

[+]

There is an association between cholesterol oxidation and Cystic Fibrosis. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2009 Sep;90(3):477-84. Epub 2009 Jul 8. PMID: 19587087

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cholesterol: Oxidation, Cystic Fibrosis

Additional Keywords : Diseases that are Linked

[+]

This pilot data suggests an anti-catabolic effect of high-dose vitamin D in patients with cystic fibrosis.Apr 30, 2017

Click here to read the entire abstract

Pubmed Data : Metabolism. 2017 May ;70:31-41. Epub 2017 Feb 11. PMID: 28403943

Article Published Date : Apr 30, 2017

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Cystic Fibrosis, Vitamin D Deficiency

[+]

Treatment with N-acetylcysteine significantly decreased the level of oxidized vitamin C and increased the level of vitamin C.Feb 28, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cyst Fibros. 2015 Mar ;14(2):211-8. Epub 2014 Oct 23. PMID: 25458464

Article Published Date : Feb 28, 2015

Study Type : Human Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Vitamin C

Diseases : Cystic Fibrosis, Inflammation, Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

Ursodeoxycholic acid and taurine have a therapeutic role in treating liver disease associated with cystic fibrosisJun 01, 1996

Click here to read the entire abstract

Pubmed Data : Hepatology. 1996 Jun;23(6):1484-90. PMID: 8675168

Article Published Date : Jun 01, 1996

Study Type : Human Study

Additional Links

Substances : Taurine, Ursodeoxycholic acid

Diseases : Cystic Fibrosis

[+]

Ursodeoxycholic acid is associated with improvement in hepatobiliary symptoms and liver function tests in adults with liver disease who have cystic fibrosis. Dec 01, 2007

Click here to read the entire abstract

Pubmed Data : Liver Int. 2007 Dec;27(10):1402-8. PMID: 18036103

Article Published Date : Dec 01, 2007

Study Type : Human Study

Additional Links

Substances : Ursodeoxycholic acid

Diseases : Cystic Fibrosis, Liver Diseases

[+]

Very high dose vitamin D is effective for correcting deficiency in children and young adults with cystic fibrosis. Jul 01, 2009

Click here to read the entire abstract

Pubmed Data : J Cyst Fibros. 2009 Jul;8(4):270-2. Epub 2009 May 15. PMID: 19447079

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Cystic Fibrosis

[+]

Vitamin A and E levels are inversely correlated with pulmonary exacerbations in cystic fibrosis. Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : J Pediatr Gastroenterol Nutr. 2007 Sep;45(3):347-53. PMID: 17873748

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Substances : Vitamin A, Vitamin E

Diseases : Cystic Fibrosis

[+]

Vitamin D inhibits pro-inflammatory cytokines in the airways of cystic fibrosis patients infected by Pseudomonas aeruginosa.Mar 28, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ital J Pediatr. 2019 Mar 29 ;45(1):41. Epub 2019 Mar 29. PMID: 30922377

Article Published Date : Mar 28, 2019

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Cystic Fibrosis, Pseudomonas aeruginosa

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Vitamin D levels and their association with oxidative stress and inflammation markers in patients with cystic fibrosis.Jan 25, 2023

Click here to read the entire abstract

Pubmed Data : Nutr Hosp. 2023 Jan 26. Epub 2023 Jan 26. PMID: 36719006

Article Published Date : Jan 25, 2023

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Cystic Fibrosis, Vitamin D Deficiency

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Vitamin D supplementation may contribute to reduced inflammation and improved lung function in cystic fibrosis.Dec 13, 2016

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2016 Dec 14. Epub 2016 Dec 14. PMID: 27966575

Article Published Date : Dec 13, 2016

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Cystic Fibrosis, Vitamin D Deficiency

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation

Additional Keywords : Risk Reduction

[+]

Vitamin E deficiency resulting in mild hemolysis in patients with cystic fibrosis can be corrected with a water-miscible form of vitamin E. Jul 01, 1977

Click here to read the entire abstract

Pubmed Data : J Clin Invest. 1977 Jul;60(1):233-41. PMID: 874086

Article Published Date : Jul 01, 1977

Study Type : Human Study

Additional Links

Substances : Vitamin E

Diseases : Cystic Fibrosis

[+]

Whole body vibration in cystic fibrosis.Dec 31, 2007

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Musculoskelet Neuronal Interact. 2008 ;8(2):179-87. PMID: 18622087

Article Published Date : Dec 31, 2007

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Therapeutic Actions : Whole-Body Vibration

[+]

Yoga may reduce immediate anxiety and joint pain in patients with cystic fibrosis.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:9429504. Epub 2016 Dec 19. PMID: 28077950

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Diseases : Cystic Fibrosis

Therapeutic Actions : Yoga

Pharmacological Actions : Anti-Anxiety Agents

[+]

Zinc supplementation is beneficial in Zinc-deficient Cystic Fibrosis patients. Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Ann Nutr Metab. 2008;52(2):152-6. Epub 2008 Apr 29. PMID: 18446019

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Zinc

Diseases : Cystic Fibrosis

[+]

Zinc supplementation reduces the number of days of oral antibiotics used to treat respiratory tract infections in children with cystic fibrosis. Mar 01, 2008

Click here to read the entire abstract

Pubmed Data : Pediatr Pulmonol. 2008 Mar;43(3):281-7. PMID: 18214943

Article Published Date : Mar 01, 2008

Study Type : Human Study

Additional Links

Substances : Zinc

Diseases : Cystic Fibrosis, Respiratory Tract Infections

[+]

Lactoferrin Decreases Inflammatory Response by Cystic Fibrosis Bronchial Cells Invaded with Burkholderia Cenocepacia Iron-Modulated BiofilmSep 30, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Immunopathol Pharmacol. 2011 Oct-Dec;24(4):1057-68. PMID: 22230411

Article Published Date : Sep 30, 2011

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Lactoferrin

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation

[+]

Curcumin has a corrective effect on the expression of genetic defects associated with cystic fibrosis in an animal model. May 10, 2010

Click here to read the entire abstract

Pubmed Data : Lab Invest. 2010 May 10. Epub 2010 May 10. PMID: 15105504

Article Published Date : May 10, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cystic Fibrosis

Additional Keywords : Genocorrective

[+]

DHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity.Jan 31, 2012

Click here to read the entire abstract

Pubmed Data : J Lipid Res. 2012 Feb ;53(2):257-65. Epub 2011 Nov 16. PMID: 22095831

Article Published Date : Jan 31, 2012

Study Type : Animal Study

Additional Links

Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid), Omega-3 Fatty Acids

Diseases : Cystic Fibrosis

Additional Keywords : Disease Reversal, Fatty Acid Desaturases

[+]

Hyperforin, a compound found within St. John's wort, has powerful anti-inflammatory therapeutic potential in reducing lung fibrosis. May 01, 2007

Click here to read the entire abstract

Pubmed Data : J Pharmacol Exp Ther. 2007 May;321(2):492-500. Epub 2007 Feb 8. PMID: 17289834

Article Published Date : May 01, 2007

Study Type : Animal Study

Additional Links

Substances : St. Johns Wort

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Cystic Fibrosis, Pulmonary Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor

[+]

Omega-3 fatty acids may have a protective effect against mucus over-production caused by pulmonary bacterial colonization in cystic fibrosis. Jun 05, 2007

Click here to read the entire abstract

Pubmed Data : Respir Res. 2007 Jun 5;8:39. PMID: 17550583

Article Published Date : Jun 05, 2007

Study Type : Animal Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Cystic Fibrosis, Pseudomonas aeruginosa

[+]

Parthenolide (from Feverfew) may down-regulate excessive inflammation in Cystic FibrosisJun 01, 2007

Click here to read the entire abstract

Pubmed Data : Am J Respir Cell Mol Biol. 2007 Jun;36(6):728-36. Epub 2007 Feb 1.PMID:17272824

Article Published Date : Jun 01, 2007

Study Type : Animal Study

Additional Links

Substances : Feverfew

Diseases : Cystic Fibrosis

[+]

Pinostrobin inhibits renal CFTR-mediated Cl- secretion and retards cyst growth in cell-derived cyst and polycystic kidney disease.Mar 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Pharmacol Sci. 2022 Apr ;148(4):369-376. Epub 2022 Feb 20. PMID: 35300812

Article Published Date : Mar 31, 2022

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Cystic Fibrosis

Pharmacological Actions : Antiproliferative , Renoprotective

[+]

Resveratrol partially rescues the refractory CFTR dependent β adrenergic response of saliva secretion in female CF mice.Jun 18, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Open. 2015 Jun 19. Epub 2015 Jun 19. PMID: 26092868

Article Published Date : Jun 18, 2015

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Cystic Fibrosis, Dry Mouth, Salivary Gland Diseases

Additional Keywords : Epigenetic Modification

[+]

A natural compound derived from Trichilia rubescens, corrects the defective CFTR gene expression in a yeast model of Cystic Fibrosis.Feb 01, 2002

Click here to read the entire abstract

Pubmed Data : Mol Med. 2002 Feb;8(2):75-87. PMID: 12080183

Article Published Date : Feb 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Trichilia rubescens

Diseases : Cystic Fibrosis

[+]

A review of thirty years of Lactobacillus rhamnosus GG.Feb 28, 2019

Click here to read the entire abstract

Pubmed Data : J Clin Gastroenterol. 2019 Mar ;53 Suppl 1:S1-S41. PMID: 30741841

Article Published Date : Feb 28, 2019

Study Type : Review

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Allergies, Cardiovascular Diseases, Cystic Fibrosis, Diarrhea, Diarrhea: Antibiotic-Associated, Gastrointestinal Diseases, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD), Respiratory Tract Infections

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Amla (Emblica officinalis) extract contains a compound known as pyrogallol which has anti-inflammatory activity in bronchial epithelial cells from patients with cystic fibrosis. Dec 10, 2008

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2008 Dec 10;8(12):1672-80. Epub 2008 Aug 27. PMID: 18760383

Article Published Date : Dec 10, 2008

Study Type : In Vitro Study

Additional Links

Substances : Amla Fruit

Diseases : Cystic Fibrosis

[+]

Anti-persisters activity of Lacticaseibacillus rhamnosus culture filtrates against Pseudomonas aeruginosa.Jun 27, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2024 Jun 28 ;25(13). Epub 2024 Jun 28. PMID: 39000222

Article Published Date : Jun 27, 2024

Study Type : In Vitro Study

Additional Links

Substances : Lactobacillus rhamnosus

Diseases : Cystic Fibrosis, Pseudomonas aeruginosa

Pharmacological Actions : Anti-Bacterial Agents

[+]

Bergamot fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.Apr 14, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Biochem. 2011 Apr 15 ;12:15. Epub 2011 Apr 15. PMID: 21496221

Article Published Date : Apr 14, 2011

Study Type : In Vitro Study

Additional Links

Substances : Bergamot orange

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Capsaicin may help correct defective expression of the CFTR gene in Cystic Fibrosis Jun 01, 2004

Click here to read the entire abstract

Pubmed Data : Mol Pharmacol. 2004 Jun;65(6):1415-26. PMID: 15155835

Article Published Date : Jun 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Cayenne

Diseases : Cystic Fibrosis

[+]

Compounds found within Coleus (forskolin) and Soy (genistein) may have therapeutic value in selective targeting CFTR channels in cystic fibrosis. Nov 01, 2009

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2009 Nov;158(5):1313-21. Epub 2009 Sep 25. PMID: 19788494

Article Published Date : Nov 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Coleus Forskohlii, Genistein

Diseases : Cystic Fibrosis

[+]

Cordyceps may play a therapeutic role in improving pulmonary function in cystic fibrosis. Apr 17, 2008

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2008 Apr 17;117(1):92-101. Epub 2008 Feb 6. PMID: 18358654

Article Published Date : Apr 17, 2008

Study Type : In Vitro Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Cystic Fibrosis

[+]

Curcumin enhances the functional competence of the cystic-fibrosis associated gene, indicating it may have value for the condition. Feb 09, 2007

Click here to read the entire abstract

Pubmed Data : Biochem Biophys Res Commun. 2007 Feb 9;353(2):351-6. Epub 2006 Dec 13. PMID: 17178109

Article Published Date : Feb 09, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cystic Fibrosis

[+]

Curcumin may have a therapeutic role in the treatment of cystic fibrosis. Jan 01, 1992

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 1992;18(2):181-9. PMID: 16424149

Article Published Date : Jan 01, 1992

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cystic Fibrosis

[+]

Curcumin may have therapeutic value in cystic fibrosis. Oct 01, 2004

Click here to read the entire abstract

Pubmed Data : Trends Mol Med. 2004 Oct;10(10):473-5. PMID: 15464445

Article Published Date : Oct 01, 2004

Study Type : Review

Additional Links

Substances : Curcumin

Diseases : Cystic Fibrosis

[+]

Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism, indicating it may have therapeutic value in the condition.Feb 16, 2007

Click here to read the entire abstract

Pubmed Data : J Biol Chem. 2007 Feb 16;282(7):4533-44. Epub 2006 Dec 18. PMID: 17178710

Article Published Date : Feb 16, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cystic Fibrosis

[+]

Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.Apr 01, 2007

Click here to read the entire abstract

Pubmed Data : J Immunotoxicol. 2007 Apr;4(2):85-96. PMID: 15582996

Article Published Date : Apr 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cystic Fibrosis

[+]

DHA may down-regulate proinflammatory linolenic acid metabolism in CF. Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : J Lipid Res. 2008 Sep;49(9):1946-54. Epub 2008 May 14 PMID: 18480495

Article Published Date : Sep 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Docosahexaenoic acid (DHA)

Diseases : Cystic Fibrosis

[+]

Evening primrose oil may partially correct the theoretical delta-6-desaturase abberation in Cystic Fibrosis.Dec 01, 1982

Click here to read the entire abstract

Pubmed Data : 1: Prostaglandins Leukot Med. 1982 Dec;9(6):615-28. PMID: 6961468

Article Published Date : Dec 01, 1982

Study Type : Review

Additional Links

Substances : Evening Primrose Oil

Diseases : Cystic Fibrosis

[+]

Exploring the mechanism of activation of CFTR by curcuminoids.Dec 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Dec 31 ;25(1). Epub 2023 Dec 31. PMID: 38203723

Article Published Date : Dec 30, 2023

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, Curcuminoids

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Fish oil supplementation has therapeutic value in the treatment of cystic fibrosis. Nov 01, 2008

Click here to read the entire abstract

Pubmed Data : J Urol. 2008 Nov;180(5):2247-53. Epub 2008 Sep 20. PMID: 17943770

Article Published Date : Nov 01, 2008

Study Type : Review

Additional Links

Substances : Fish Oil

Diseases : Cystic Fibrosis

[+]

Flavonoids may contribute to correction of the expression of the CFTR gene in Cystic Fibrosis.Nov 01, 1998

Click here to read the entire abstract

Pubmed Data : Am J Physiol. 1998 Nov;275(5 Pt 1):L902-10. PMID: 9815107

Article Published Date : Nov 01, 1998

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Cystic Fibrosis

[+]

Flavonoids may improve the expression of the defective CFTR gene in Cystic Fibrosis.Jan 01, 2002

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2002;43(1):76-81. PMID: 15191910

Article Published Date : Jan 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Cystic Fibrosis

[+]

Genistein has a genocorrective effect in Cystic Fibrosis Oct 01, 2002

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2002 Oct;137(4):504-12. PMID: 12359632

Article Published Date : Oct 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Cystic Fibrosis

[+]

Genistein may be useful in patients with cystic fibrosis and the G551D-CFTR mutation.Dec 27, 2002

Click here to read the entire abstract

Pubmed Data : J Biol Chem. 2002 Dec 27;277(52):50341-7. Epub 2002 Oct 16. PMID: 12386156

Article Published Date : Dec 27, 2002

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Cystic Fibrosis

[+]

Genistein may help correct defective CFTR gene in Cystic FibrosisSep 01, 1997

Click here to read the entire abstract

Pubmed Data : Am J Physiol. 1997 Sep;273(3 Pt 1):C988-98. PMID: 9316420

Article Published Date : Sep 01, 1997

Study Type : In Vitro Study

Additional Links

Substances : Genistein, Isoflavones

Diseases : Cystic Fibrosis

[+]

Genistein restores functional interactions between Delta F508-CFTR and ENaC in Xenopus oocytes.Mar 15, 2002

Click here to read the entire abstract

Pubmed Data : J Biol Chem. 2002 Mar 15;277(11):8928-33. Epub 2001 Dec 28. PMID: 11773060

Article Published Date : Mar 15, 2002

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Cystic Fibrosis

[+]

Genistein would likely ameliorate cystic fibrosis symptoms in individuals with the rare S1045Y-CFTR mutation.Jun 02, 2016

Click here to read the entire abstract

Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 2016 Jun 3:ajplung.00134.2016. Epub 2016 Jun 3. PMID: 27261451

Article Published Date : Jun 02, 2016

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Cystic Fibrosis

[+]

Korean red ginseng aqueous extract improves markers of mucociliary clearance by stimulating chloride secretion.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Ginseng Res. 2021 Jan ;45(1):66-74. Epub 2019 Sep 13. PMID: 33437158

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Cystic Fibrosis

[+]

Lactoferrin inhibits Pseudomonas aeruginosa and Burkholderia cenocepia, two infectious organisms found in Cystic Fibrosis patients.Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Int J Immunopathol Pharmacol. 2008 Jan-Mar;21(1):51-9. PMID: 18336731

Article Published Date : Jan 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Lactoferrin

Diseases : Burkholderia Infections, Cystic Fibrosis, Pseudomonas aeruginosa

[+]

NAC has good antibacterial properties and the ability to interfere with biofilm formation and disrupt biofilms.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Respir Med. 2016 08 ;117:190-7. Epub 2016 Jun 16. PMID: 27492531

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Cystic Fibrosis, Upper Respiratory Infections

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

[+]

Novel therapy of bicarbonate, glutathione and ascorbic acid improves cystic fibrosis mucus transport.May 05, 2020

Click here to read the entire abstract

Pubmed Data : Am J Respir Cell Mol Biol. 2020 May 6. Epub 2020 May 6. PMID: 32374624

Article Published Date : May 05, 2020

Study Type : In Vitro Study

Additional Links

Substances : Glutathione, Sodium Bicarbonate, Vitamin C

Diseases : Cystic Fibrosis

[+]

Olive leaf extract as a novel antioxidant that ameliorates the inflammatory response in cystic fibrosis.Jun 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cells. 2023 Jul 1 ;12(13). Epub 2023 Jul 1. PMID: 37443798

Article Published Date : Jun 30, 2023

Study Type : In Vitro Study

Additional Links

Substances : Olive leaf extract

Diseases : Cystic Fibrosis, Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Pleiotropic effect of vitamin D in cystic fibrosis.Aug 14, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Adv Respir Med. 2018 Aug 15. Epub 2018 Aug 15. PMID: 30110122

Article Published Date : Aug 14, 2018

Study Type : Review

Additional Links

Diseases : Cystic Fibrosis, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Probiotics decrease gut dysbiosis and improve gut maturity and function. Aug 29, 2016

Click here to read the entire abstract

Pubmed Data : Eur J Pediatr. 2016 Aug 30. Epub 2016 Aug 30. PMID: 27576473

Article Published Date : Aug 29, 2016

Study Type : Review

Additional Links

Substances : Probiotics

Diseases : Cystic Fibrosis, Dysbiosis

Pharmacological Actions : Gastrointestinal Agents

[+]

Probiotics significantly reduce faecal calprotectin in children and adults with cystic fibrosis.Jan 21, 2020

Click here to read the entire abstract

Pubmed Data : Cochrane Database Syst Rev. 2020 Jan 22 ;1:CD012949. Epub 2020 Jan 22. PMID: 31962375

Article Published Date : Jan 21, 2020

Study Type : Review

Additional Links

Substances : Probiotics

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

[+]

Prolonged breastfeeding is beneficial in children with cystic fibrosis and may protect them against decline of pulmonary function.Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : Acta Paediatr. 2007 Aug;96(8):1228-32. Epub 2007 Jun 21. PMID: 17590186

Article Published Date : Aug 01, 2007

Study Type : Review

Additional Links

Substances : Breast Milk

Diseases : Cystic Fibrosis, Postnatal Care: Breastfeeding

Therapeutic Actions : Breastfeeding

[+]

Role of inflammation and oxidative stress in tissue damage associated with cystic fibrosis: CAPE as a future therapeutic strategy.Sep 15, 2021

Click here to read the entire abstract

Pubmed Data : Mol Cell Biochem. 2021 Sep 16. Epub 2021 Sep 16. PMID: 34529223

Article Published Date : Sep 15, 2021

Study Type : Review

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Cystic Fibrosis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

The CFTR mutation in cystic fibrosis may result in reduced glutathione transport, indicating glutathione supplementation may play a critical role in slowing disease progression. Jun 15, 2001

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2001 Jun 15;30(12):1440-61. PMID: 11390189

Article Published Date : Jun 15, 2001

Study Type : Commentary

Additional Links

Substances : Glutathione

Diseases : Cystic Fibrosis

[+]

The present data indicate a promising future for probiotic use in cystic fibrosis.Feb 28, 2019

Click here to read the entire abstract

Pubmed Data : J Pediatr Gastroenterol Nutr. 2019 Mar ;68(3):394-399. PMID: 30358738

Article Published Date : Feb 28, 2019

Study Type : Review

Additional Links

Substances : Probiotics

Diseases : Cystic Fibrosis

[+]

The use of honey as a combination agent may be possible for the management of P. aeruginosa and B. cepacia.Apr 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arch Microbiol. 2015 May ;197(4):597-601. Epub 2015 Feb 14. PMID: 25680398

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Manuka Honey

Diseases : Cystic Fibrosis, Gram-Negative Bacterial Infections, Pseudomonas aeruginosa

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

This review highlight some of the proposed therapies arising from natural sources that have been proposed to be of benefit to CF patients.Jan 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Genet Syndr Gene Ther. 2016 Feb ;7(1). Epub 2016 Jan 30. PMID: 27081574

Article Published Date : Jan 31, 2016

Study Type : Review

Additional Links

Substances : Curcumin, Genistein, Resveratrol

Diseases : Cystic Fibrosis

[+]

This review will focus on vitamin D as a potential candidate to treat or prevent exacerbations in cystic fibrosis, COPD, and asthma.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Calcif Tissue Int. 2020 Jan ;106(1):76-87. Epub 2019 Jul 26. PMID: 31350569

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : Vitamin D

Diseases : Asthma, Chronic Obstructive Pulmonary Disease, Cystic Fibrosis, Respiratory Diseases

Pharmacological Actions : Immunomodulatory

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Vitamin C is a biolgical regulator of CFTR-mediated CL secretion in epithelia, indicating its potential for the treatment of sticky airway secretions in Cystic Fibrosis.Mar 09, 2004

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Pubmed Data : Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3691-6. Epub 2004 Mar 1. PMID: 14993613

Article Published Date : Mar 09, 2004

Study Type : In Vitro Study

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Substances : Vitamin C

Diseases : Cystic Fibrosis

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DHA increases resistance to Pseudomonas aeruginosa infection. Apr 01, 2009

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Pubmed Data : Biochem J. 2009 Apr 1;419(1):193-200. PMID: 19105793

Article Published Date : Apr 01, 2009

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Substances : DHA (Docosahexaenoic Acid)

Diseases : Cystic Fibrosis, Lung Diseases, Pseudomonas aeruginosa, Pseudomonas Infections

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Plant source enzymes may provide ideal acid-stable adjunct to pancreatin derived enzymes.Feb 01, 2010

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Pubmed Data : Metabolism. 2010 Feb;59(2):285-92. Epub 2009 Oct 1. PMID: 7865271

Article Published Date : Feb 01, 2010

Additional Links

Substances : Enzyme Therapy

Diseases : Cystic Fibrosis

Cystic Fibrosis jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

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View the Evidence: 122 Abstracts with Cystic Fibrosis Research

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There is currently no evidence from randomised studies that influenza vaccine given to people with cystic fibrosis is of benefit to them. Oct 07, 2009

Gut Bifidobacteria enrichment following oral Lactobacillus-supplementation is associated with clinical improvements in children with cystic fibrosis.Jul 27, 2022

5-methyltehydrofolate (folic acid) and vitamin B12 ameliorate red blood cell abnormalities in pediatric patients with Cystic Fibrosis. Jan 01, 2009

A high lipase pancreatic enzyme is superior to regular pancreatin in adult cystic fibrosis patients. Dec 01, 1994

Acupuncture is effective for managing symptoms and illnesses associated with cystic fibrosis. Jan 01, 2005

An 8-month treatment with omega-3 fatty acids (EPA and DHA) has a positive effects, such as decreasing inflammation, in patients with cystic fibrosis. Jan 01, 2003

An antioxidant formula increases important fat-soluble nutrients and antioxidants and reduces airway inflammation in patients with Cystic Fibrosis. Jan 01, 2008

Annual influenza vaccination hampers the development of virus-specific CD8(+) T cell responses necessary to protect against influenza infection. Nov 01, 2011

Antioxidant supplementation may have therapeutic value in the treatment of cystic fibrosis - Article 2. Jan 01, 2003

Antioxidant supplementation may have therapeutic value in the treatment of cystic fibrosis - Article 2. Apr 01, 1994

Beta-carotene supplementation ameliorates deficiencies and reduces oxidative stress in Cystic Fibrosis patients. Jan 01, 2000

Bisphosphonates used for osteoporosis in patients with cystic fibrosis increases bone mineral density without increasing bone quality/strength, while causing bone pain and flu-like symptoms. Jan 01, 2009

Bolus weekly vitamin D3 supplementation impacts gut and airway microbiota in adults with cystic fibrosis.Dec 31, 2017

Candida albicans chronic colonisation in cystic fibrosis may be associated with inhaled antibiotics.Jun 30, 2015

Choline-related supplements may improve status of children with Cystic FibrosisMar 01, 2007

Coenzyme Q10 levels are low in children with cystic fibrosis, indicating that supplementation could be beneficial. Apr 01, 2002

Corticosteroids contribute to muscle weakness in Cystic Fibrosis patients. Oct 01, 2003

Cysteamine plus epigallocatechin gallate can be used for autophagy-dependent rescue of class II-mutated CFTR.Mar 31, 2016

Daily vitamin D supplementation was associated with reduced Aspergillus induced IL-13 responses.Dec 31, 2014

Engaged spirituality supports pro-adherence determinants and behaviour in patients with cystic fibrosis.Mar 31, 2016

Exposure to Proton pump inhibitors is associated with higher numbers of hospitalizations for pulmonary exacerbation in cystic fibrosis patients.Sep 30, 2017

Flaxseed modulates inflammatory and oxidative stress biomarkers in cystic fibrosis.May 12, 2015

Fractional exhalation nitric oxide changes in cystic fibrosis patients induced by compound honey syrup.Dec 04, 2023

Glutathione improves clinical markers in cystic fibrosis patients. Sep 01, 2008

High dose vitamin K is efficacious in correcting vitamin K deficiency in cystic fibrosis. Sep 01, 2008

Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein.Dec 01, 2003

Inhaled glutathione improves symptoms in patients with cystic fibrosis. Jan 01, 2005

Inhaled hypertonic saline accelerates mucus clearance and improves lung function in patients with cystic fibrosis. Jan 19, 2006

Inhaled hypertonic saline significantly reduces the incidence of pulmonary exacerbations in patients with cystic fibrosis. Jan 19, 2006

Inspiratory muscle training is associated with significant improvements in physical endurance and strength in patients with Cystic Fibrosis. Nov 01, 2005

L-arginine improves exhaled nitric oxide and pulmonary function in patients with cystic fibrosis. Jul 15, 2006

L-arginine supplementation improve nitric oxide formation in cystic fibrosis patients who exhibit decreased levels of exhaled nitric oxide. Jan 01, 2005

L-ascorbate may offer potential as a therapeutic agent for the improvement of chronic rhinosinusitis in patients with cystic fibrosis. May 01, 2009

Lactobacillus GG supplementation reduces pulmonary exacerberations and hospital admissions in patients with cystic fibrosis. Jul 01, 2009

Listening to motivational music while walking elicits more positive affective response in patients with cystic fibrosis.Apr 30, 2016

Manuka honey versus saline sinus irrigation in the treatment of cystic fibrosis-associated chronic rhinosinusitis.Aug 26, 2020

N-acetylcysteine increases the fluidity of airway mucus in patients with Cystic Fibrosis. Oct 01, 2004

N-acetylcysteine reduces inflammation in patients with cystic fibrosis. Mar 21, 2006

Omega-3 and gamma-linolenic fatty acids improve pulmonary status (lung function, respiratory exacerbations and antibiotic consumption), inflammatory and anthropometric parameters in adults with CF.Dec 30, 2009

Omega-3 fatty acid supplementation reduces inflammatory biomarkers, erythrocyte sedimentation rate, and interleukin-8 concentrations in cystic fibrosis patients.May 01, 2010

Omega-3 supplementation offers several clinical benefits as to the number of exacerbations and duration of antibiotic therapy in CF patients.Apr 30, 2016

Oral DHA shifts the phospholipid fatty acid profile in patients with cystic fibrosis to a less pro-inflammatory profile. Feb 01, 2008

Oral magnesium supplementation may help overcome the failure of rhDNase-I in patients with cystic fibrosis. Nov 01, 2006

Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects. Mar 01, 2009

Oral supplementation with pressurized whey improves nutritional status and can have additional beneficial effects on inflammation in patients with cystic fibrosis.Feb 01, 2010

Physical theray and massage reduces pain and improves the ease of breathing in adults with cystic fibrosis. Jan 01, 2009

Potato crisp consumption without pancreatic enzyme supplementation has been reported to cause distal intestinal obstruction in patients with cystic fibrosis.Sep 01, 2007

Probiotics improve the intestinal function of patients with cystic fibrosis. Dec 01, 2008

Probiotics may improve respiratory and gastrointestinal outcomes in a stable cystic fibrosis population.Sep 28, 2016

Probiotics might ameliorate the dysbiosis of cystis fibrosis gut microbiota.Nov 30, 2014

Significantly altered gut microbiota, including reduced microbial diversity was seen in cystic fibrosis patients compared to healthy controls.Mar 08, 2017

Silibinins and curcumin as promising ligands against mutant cystic fibrosis transmembrane regulator protein.Jul 22, 2024

Taurine may be a useful adjunct in patients with cystic fibrosis and severe steatorrhea.Dec 01, 1991

The inability of patients with cystic fibrosis to produce adequate lactoferrin contributes to the pathogenesis of P. aeruginosa lung infection.Oct 01, 2004

The omega-3 fatty acids decrease serum leukotriene B4 in patients with cystic fibrosis. Oct 01, 1994

The probiotic Lactobacillus GG reduces intestinal inflammation in patients with cystic fibrosis. Apr 01, 2006

There is a different microbiome gene repertoire in the airways of cystic fibrosis patients with severe lung disease.Jul 28, 2017

There is an association between cholesterol oxidation and Cystic Fibrosis. Sep 01, 2009

This pilot data suggests an anti-catabolic effect of high-dose vitamin D in patients with cystic fibrosis.Apr 30, 2017

Treatment with N-acetylcysteine significantly decreased the level of oxidized vitamin C and increased the level of vitamin C.Feb 28, 2015

Ursodeoxycholic acid and taurine have a therapeutic role in treating liver disease associated with cystic fibrosisJun 01, 1996

Ursodeoxycholic acid is associated with improvement in hepatobiliary symptoms and liver function tests in adults with liver disease who have cystic fibrosis. Dec 01, 2007

Very high dose vitamin D is effective for correcting deficiency in children and young adults with cystic fibrosis. Jul 01, 2009

Vitamin A and E levels are inversely correlated with pulmonary exacerbations in cystic fibrosis. Sep 01, 2007

Vitamin D inhibits pro-inflammatory cytokines in the airways of cystic fibrosis patients infected by Pseudomonas aeruginosa.Mar 28, 2019

Vitamin D levels and their association with oxidative stress and inflammation markers in patients with cystic fibrosis.Jan 25, 2023

Vitamin D supplementation may contribute to reduced inflammation and improved lung function in cystic fibrosis.Dec 13, 2016

Vitamin E deficiency resulting in mild hemolysis in patients with cystic fibrosis can be corrected with a water-miscible form of vitamin E. Jul 01, 1977

Whole body vibration in cystic fibrosis.Dec 31, 2007

Yoga may reduce immediate anxiety and joint pain in patients with cystic fibrosis.Dec 31, 2015

Zinc supplementation is beneficial in Zinc-deficient Cystic Fibrosis patients. Jan 01, 2008

Zinc supplementation reduces the number of days of oral antibiotics used to treat respiratory tract infections in children with cystic fibrosis. Mar 01, 2008

Cystic Fibrosis

View the Evidence:
122 Abstracts with Cystic Fibrosis Research