Delirium

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4 Substances Researched for Delirium

Name	AC	CK
Melatonin	6	82
Vitamin D	1	10
Jujube	1	2
Tangeretin	1	2

1 Therapeutic Actions Researched for Delirium

Name	AC	CK	Focus
Acupuncture	1	10

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
14 Abstracts with Delirium Research

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Melatonin receptor agonists for the prevention of delirium.May 05, 2022

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Pubmed Data : Curr Neuropharmacol. 2022 May 6. Epub 2022 May 6. PMID: 35524672

Article Published Date : May 05, 2022

Study Type : Meta Analysis, Review

Additional Links

Substances : Melatonin

Diseases : Delirium

Pharmacological Actions : Neuroprotective Agents

[+]

Melatonin may decrease the incidence of delirium for special ICU patients.Mar 21, 2024

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Pubmed Data : Altern Ther Health Med. 2024 Mar 22. Epub 2024 Mar 22. PMID: 38518134

Article Published Date : Mar 21, 2024

Study Type : Meta Analysis

Additional Links

Substances : Melatonin

Diseases : Delirium

Additional Keywords : Risk Reduction

[+]

Melatonin supplementation had a significant preventive effect in decreasing the incidence of delirium in elderly patients.Jul 20, 2015

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Pubmed Data : Mol Neurobiol. 2015 Jul 21. Epub 2015 Jul 21. PMID: 26189834

Article Published Date : Jul 20, 2015

Study Type : Meta Analysis

Additional Links

Substances : Melatonin

Diseases : Delirium

Additional Keywords : Risk Reduction, Significant Treatment Outcome

[+]

Perioperative melatonin reduced the incidence of delirium in older adults in the included studies. Oct 15, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Geriatr. 2019 Oct 16 ;19(1):272. Epub 2019 Oct 16. PMID: 31619178

Article Published Date : Oct 15, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Melatonin

Diseases : Delirium

Pharmacological Actions : Neuroprotective Agents

[+]

Acupuncture seems to be safe and effective in the treatment of delirium in older patients.Mar 08, 2021

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Pubmed Data : J Geriatr Psychiatry Neurol. 2021 Mar 9:891988721996804. Epub 2021 Mar 9. PMID: 33685268

Article Published Date : Mar 08, 2021

Study Type : Human Study

Additional Links

Diseases : Delirium

Therapeutic Actions : Acupuncture

[+]

Circadian melatonin disruption can be used as an indicator of delirium.Sep 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sleep Sci. 2016 Oct-Dec;9(4):285-288. Epub 2016 Aug 10. PMID: 28154742

Article Published Date : Sep 30, 2016

Study Type : Human Study

Additional Links

Substances : Melatonin

Diseases : Circadian Dysregulation, Delirium

[+]

Decreased serum 25OHD concentrations were associated with delirium among acute geriatric inpatients.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Neurol. 2020 ;11:1034. Epub 2020 Sep 18. PMID: 33071932

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Delirium, Vitamin D Deficiency

Additional Keywords : Increased Risk

[+]

Effects of melatonin on postoperative delirium.Oct 20, 2021

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Pubmed Data : Heart Surg Forum. 2021 Oct 21 ;24(5):E893-E897. Epub 2021 Oct 21. PMID: 34730495

Article Published Date : Oct 20, 2021

Study Type : Human Study

Additional Links

Substances : Melatonin

Diseases : Delirium

Pharmacological Actions : Neuroprotective Agents

[+]

Pre-operative C-reactive protein levels were independently associated with post-operative delirium.Jul 07, 2019

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Pubmed Data : Acta Anaesthesiol Scand. 2019 Jul 8. Epub 2019 Jul 8. PMID: 31283835

Article Published Date : Jul 07, 2019

Study Type : Human Study

Additional Links

Diseases : C-Reactive Protein (CRP), Delirium, Inflammation

Additional Keywords : Risk Factors

[+]

Jujuboside A ameliorates cognitive deficiency in delirium.Jul 04, 2023

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Pubmed Data : J Pharm Pharmacol. 2023 Jul 5 ;75(7):886-897. PMID: 37330271

Article Published Date : Jul 04, 2023

Study Type : Animal Study

Additional Links

Substances : Jujube

Diseases : Delirium, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Tangeretin prevents cognitive deficit in delirium through activating RORα/γ-E4BP4 axis in mice.Oct 31, 2022

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Pubmed Data : Biochem Pharmacol. 2022 Nov ;205:115286. Epub 2022 Oct 8. PMID: 36216079

Article Published Date : Oct 31, 2022

Study Type : Animal Study

Additional Links

Substances : Tangeretin

Diseases : Cognitive Decline/Dysfunction, Delirium, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

In the absence of definitive pharmacologic therapy, interventions prioritizing maintenance of normal circadian, sleep, and behavioral patterns have shown promise in delirium risk reduction.Jul 05, 2015

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Pubmed Data : Curr Pharm Des. 2015 Jul 6. Epub 2015 Jul 6. PMID: 26144937

Article Published Date : Jul 05, 2015

Study Type : Review

Additional Links

Diseases : Circadian Dysregulation, Delirium

Additional Keywords : Risk Reduction

[+]

Melatonin could be of use in the prevention and management of delirium.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Med (Lausanne). 2017 ;4:242. Epub 2018 Jan 8. PMID: 29376051

Article Published Date : Dec 31, 2016

Study Type : Review

Additional Links

Substances : Melatonin

Diseases : Delirium

[+]

Systemic inflammation is a major contributor to the progression of dementia.Jul 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biochem Soc Trans. 2011 Aug ;39(4):945-53. PMID: 21787328

Article Published Date : Jul 31, 2011

Study Type : Review

Additional Links

Diseases : Alzheimer's Disease, Delirium, Dementia, Inflammation

Additional Keywords : Increased Risk

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 14 Abstracts with Delirium Research

Limited to Members Only

Currently Available Sorting Options

Melatonin receptor agonists for the prevention of delirium.May 05, 2022

Melatonin may decrease the incidence of delirium for special ICU patients.Mar 21, 2024

Melatonin supplementation had a significant preventive effect in decreasing the incidence of delirium in elderly patients.Jul 20, 2015

Perioperative melatonin reduced the incidence of delirium in older adults in the included studies. Oct 15, 2019

Acupuncture seems to be safe and effective in the treatment of delirium in older patients.Mar 08, 2021

Circadian melatonin disruption can be used as an indicator of delirium.Sep 30, 2016

Decreased serum 25OHD concentrations were associated with delirium among acute geriatric inpatients.Dec 31, 2019

Effects of melatonin on postoperative delirium.Oct 20, 2021

Pre-operative C-reactive protein levels were independently associated with post-operative delirium.Jul 07, 2019

Jujuboside A ameliorates cognitive deficiency in delirium.Jul 04, 2023

Tangeretin prevents cognitive deficit in delirium through activating RORα/γ-E4BP4 axis in mice.Oct 31, 2022

In the absence of definitive pharmacologic therapy, interventions prioritizing maintenance of normal circadian, sleep, and behavioral patterns have shown promise in delirium risk reduction.Jul 05, 2015

Melatonin could be of use in the prevention and management of delirium.Dec 31, 2016

Systemic inflammation is a major contributor to the progression of dementia.Jul 31, 2011

Delirium Related Articles

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Delirium

View the Evidence:
14 Abstracts with Delirium Research