Depression

Name	AC	CK
Saffron	28	294
Vitamin D	26	237
Ayahuasca	27	193
Psilocybin	26	173
Curcumin	26	158
Probiotics	29	146
Magnesium	10	93
Omega-3 Fatty Acids	12	86
Fruit: All	8	82
Vegetables: All	7	72
Psychedelics:All	14	66
Homeopathic Medicine: All	6	60
St. John's Wort	5	60
Lavender	5	50
Rhodiola (Tibetan Ginseng)	5	42
Ginsenosides	21	41
DHA (Docosahexaenoic Acid)	3	40
EPA (Eicosapentaenoic Acid)	3	40
Flavonoids	14	40
Vitamin B-12	4	40
Lavender: Essential Oil	5	36
Polyunsaturated Fatty Acids (PUFAs)	6	36
Lysergic Acid Diethylamide (LSD)	13	33
Coffee	4	32
Rosemary	8	31
5-HTP (5-Hydroxytryptophan)	2	30
Fish	3	30
Kava Kava	2	30
SAMe (S-adenosylmethionine)	2	30
Tryptophan	3	30
Vitamin B-6	3	30
Crocin	7	29
Cannabidiol	16	26
Blueberry	4	24
Coenzyme Q10	4	24
Indian Mulberry	3	24
Lemon Balm	4	24
Paeoniflorin	12	24
Fiber	3	23
Ginkgo biloba	3	23
St. Johns Wort	6	23
Vitamin C	8	23
Chamomile	3	22
Oligosaccharides	2	22
Acetyl-l-carnitine	2	20
Bergamot	2	20
Carotenoids	2	20
Chlorella (Algae)	2	20
Dehydroepiandrosterone (DHEA)	1	20
Docosahexaenoic acid (DHA)	1	20
Eicosapentaenoic acid (EPA)	1	20
Inositol	1	20
Riboflavin (Vitamin B-2)	2	20
Soy	2	20
Yoghurt	2	20
Green Tea	6	17
Lion's Mane (Hericium Erinaceus)	6	17
Melatonin	10	16
NAC (N-acetyl-L-cysteine)	4	16
Fenugreek	4	15
Rose	4	15
Bifidobacterium Longum	3	14
Magnolia	3	14
Palmitoylethanolamide	4	14
Prebiotics	5	14
Ashwagandha	3	13
Arginine	2	12
Bacopa	7	12
Berberine	6	12
Dandelion	2	12
Goji	2	12
Hesperidin	6	12
Lutein	2	12
Motherwort	2	12
Zinc	2	12
Black Tea	2	11
Cocoa	2	11
Cysteine (see N-Acetylcysteine)	2	11
Frankincense	2	11
Walnut	2	11
Alpha-Lipoic Acid	1	10
B-Carotene	1	10
Blue-Green Algae	1	10
Chocolate	1	10
DHEA (Dehydroepiandrosterone)	1	10
Essential Fatty Acids	1	10
Eucalyptus	1	10
Hops	1	10
Maca	1	10
Marjoram	1	10
Niacin	1	10
Nuts	1	10
Piperidines	1	10
Polyphenols	7	10
Quercetin	5	10
Resveratrol	6	10
Selenium	1	10
Vitamin B-3 (Niacin)	1	10
Vitamin B-5 (Pantothenic Acid)	1	10
Vitamin E	1	10
White Tea	1	10
Ferulic acid	5	9
Perillaldehyde	4	8
Piperine	4	8
Chrysin	4	7
Thymoquinone	4	7
Anise	3	6
Arctigenin	3	6
Astaxanthin	3	6
Banana	3	6
Beta-Caryophyllene	3	6
Gastrodin	3	6
Ginseng	3	6
Honokiol	3	6
Magnolol	3	6
Mulberry	4	6
Naringenin	3	6
Passion Flower	4	6
Silymarin	3	6
Ursolic Acid	4	6
Hyperforin	3	5
Valerian	3	5
Allicin	2	4
Apigenin	2	4
Asparagus	2	4
Bamboo	2	4
Bifidobacterium	2	4
Caffeine	2	4
Chlorogenic Acid	2	4
Citrus naringin	2	4
Coconut Husk/Fiber	2	4
Flaxseed	2	4
Gardenia	2	4
Genipin	2	4
Ginseng (Korean)	2	4
Lactobacillus helveticus	2	4
Liquiritigenin	2	4
Lotus	2	4
Luteolin	2	4
Moringa oleifera	2	4
Onion	2	4
Paeonol	2	4
Peony	2	4
Royal Jelly	2	4
Safflower	2	4
Salvia divinorum	3	4
Sesamin	2	4
Silibinin	2	4
Sulforaphane	2	4
Tanshinone IIA	2	4
Theanine	2	4
Anthocyanins	2	3
Bael	2	3
Cannabinoids	2	3
Cannabis	2	3
Catechin	2	3
Corn Silk	2	3
Dogwood	2	3
Folic Acid	2	3
Genistein	2	3
Huperzine	2	3
Mangiferin	2	3
Panax Notoginseng	2	3
Perilla	2	3
Poria cocos	2	3
Quince	2	3
Angelica	1	2
Asiatic Acid	1	2
Astragaloside	1	2
Astragalus	1	2
Bai Zhu	1	2
Banana Stem	1	2
Basil	1	2
Bifidobacterium Infantis	1	2
Bitter Orange	1	2
Black Pepper	1	2
Broccoli Sprouts	1	2
Burdock	1	2
Catuaba	1	2
Celery Oil	1	2
Chia	1	2
Chokeberry	1	2
Chrysanthemum Morifolium	1	2
Coconut Water	1	2
Crocetin	1	2
Curry Leaves	1	2
D-Limonene	1	2
Delta-tetrahydrocannabinol (THC)	1	2
Dill	1	2
Ellagic Acid	1	2
Eriodictyol	1	2
FOS (Fructooligosaccharides)	1	2
Feijoa	1	2
Feverfew	1	2
Fisetin	1	2
Fish Oil	1	2
Fucoidan	1	2
Fucoxanthin	1	2
Gallic Acid	1	2
Garcinia Mangostana	1	2
Garlic	1	2
Geraniol	1	2
Geranium	1	2
Ginger	1	2
Gotu Kola	1	2
Grape Seed Extract	1	2
Gynostemma	1	2
Hawthorn	1	2
Hibiscus	1	2
Honeysuckle	1	2
Hydrogen Water	1	2
Isoquercitrin	1	2
Kratom	2	2
Krill	1	2
Kudzu	1	2
Lactobacillus kefiranofaciens	1	2
Lactobacillus paracasei	1	2
Lactobacillus reuteri	1	2
Lactobacillus rhamnosus	1	2
Lactoferrin	1	2
Lemon	1	2
Lemon Verbena	1	2
Lettuce	1	2
Ligustrazine	1	2
Lobelia	1	2
Mango	1	2
Medicinal Mushrooms	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Musk (Animal)	1	2
Myricetin	1	2
Nettle	1	2
Noni	1	2
Nutmeg	1	2
Okra	1	2
Oleuropein	1	2
Orange	1	2
Orange: Mandarin	1	2
P-Coumaric Acid	1	2
Panax Ginseng	1	2
Patchouli	1	2
Piperlongumine	1	2
Pomegranate	1	2
Propolis: Bee	1	2
Pterostilbene	1	2
Pycnogenol (Pine Bark)	1	2
Radish	1	2
Red Sage	1	2
Rosemaric Acid	1	2
Rutin	1	2
S-Adenosylmethionine (SAMe)	2	2
Safranal	1	2
Sage	1	2
Schisandra	1	2
Seaweed: Brown	1	2
Sesamol	1	2
Spinach	1	2
Strawberry	1	2
Tarragon	1	2
Theaflavins	1	2
Thistle	1	2
Tualang Honey	1	2
Vitamin E: alpha tocopherol	1	2
Vitamin K2	1	2
White Mulberry	1	2
Xanthohumol	1	2
Zataria multiflora	1	2
ALA (Alpha-Linolenic Acid)	1	1
Amla Fruit	1	1
Babchi	1	1
Cannabichromene	1	1
Cannabigerol	1	1
Carnosic Acid	1	1
Carnosol	1	1
Clove	1	1
Curcumin: Degradiation byproducts	1	1
EGCG (Epigallocatechin gallate)	1	1
Endocannabinoids	1	1
Grape	1	1
Graviola	1	1
Harmine	1	1
Mangosteen	1	1
Mistletoe	1	1
Nigella sativa (aka Black Seed)	1	1
Nobiletin	1	1
Oak	1	1
Oridonin	1	1
Pantothenic Acid (Vitamin B-5)	1	1
Pistachio nut	1	1
Reishi Mushroom	1	1
Rhubarb	1	1
Rosmarinic acid	1	1
Sea buckthorn	1	1
Skullcap: Chinese	1	1
Soursop	1	1
Syrian rue	1	1
Xanthones	1	1
rhodiola	1	1

Name	AC	CK
Fluoxetine (trade name Prozac)	22	174
Antidepressants	9	85
Sugar Sweetened Beverages	3	40
Sertraline	6	36
Oral Contraceptives	4	33
Selective Serotonin Reuptake Inhibitors (SSRIs)	3	22
Chemotherapy	1	20
Energy Drinks	2	20
Eszopiclone	1	20
Hypnotic Drugs	1	20
Ramelteon	1	20
Statin Drugs	2	20
Zaleplon	1	20
Zolpidem (trade name Ambien)	1	20
Bisphenol A	4	15
Simvastatin	2	11
Analgesic: Non-opioid	1	10
Aspirin	1	10
Clozapine	1	10
Electronic Cigarettes	1	10
Fenofibrates	1	10
Fried Foods	1	10
Gliadin	1	10
Hydrocarbons	1	10
Nicotine	1	10
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	10
Phthalates	1	10
Tobacco: Smoking	1	10
Tricresyl phosphates (TCPs)	1	10
Glyphosate	2	4
Dexamethasone	2	3
Oseltamivir (trade name Tamiflu)	1	3
Paroxetine (trade names Seroxat, Paxil)	1	3
Antibiotics	1	2
Arsenic	1	2
Bisphenol F	1	2
Concanavalin A	1	2
Monosodium Glutamate (MSG)	1	2
Prescription Drugs	1	2

Name	AC	CK
Exercise	44	361
Yoga	35	289
Mindfullness Training	17	152
Acupuncture	16	145
Qigong	12	133
Meditation	16	125
Integrative Medicine	7	90
Tai Chi	8	82
Horticultural Therapy (Gardening)	6	70
Music	8	64
Electroacupuncture	12	55
Light Therapy	4	50
Exercise: Aerobic	5	42
Shinrin-yoku (taking in the atmosphere of the forest)	6	42
Aromatherapy Massage	5	41
Emotional Freedom Technique	5	41
Exercise: Green	5	41
Hyperbaric Treatment	2	40
Massage/Therapeutic Touch	3	40
Pilates	3	40
Yogic Technique: Sudarshan kriya	6	33
Aromatherapy	4	31
Guided Imagery	4	31
Acupressure	3	30
Cryotherapy	3	30
Exercise: Cycling	3	30
Therapeutic Breathing	3	30
Art Therapy	3	21
Dietary Modification: Mediterranean Diet	3	21
Laughter/Humor	3	21
Cognitive Behavioural Approaches	2	20
Exercise: Resistance Training	2	20
Hydrotherapy	2	20
Placebo Effect	2	20
Thermal Therapy: Far-Infrared	2	20
Acupressure: Auricular	1	10
Behavioral Treatment	1	10
Color Therapy	1	10
Dancing	1	10
Dietary Modification: Vegetarian	1	10
Homeopathic Treatment	1	10
Hormone Replacement Therapy	1	10
Hypnosis	1	10
Positive Mood	1	10
Prevent Pain	1	10
Reiki Therapy	1	10
Sauna Therapy	1	10
Sound Therapy	1	10
Sunlight exposure	1	10
Whole-Body Vibration	1	10
Yogic Breathing	1	10
Dietary Modification: Low Carbohydrate/Ketogenic	4	7
Exercise: Running	1	2
Laser Treatment: Low-Level	1	1
Mediterranean diet	1	1

Name	AC	CK
Electromagnetic Field Harms	4	23
Western Diet	3	22
Mobile Phone Radiation	3	21
Chemotherapy	1	20
Vaccination: All	2	13
Angioplasty	2	12
Blue Light (400−495 nm)	2	12
Electromagnetic Radiation	2	12
Air Travel	1	10
Nocebo Effect	1	10
X-ray Mammography	1	10
Vaccination: HPV (Gardasil)	1	3
Vasectomy	1	3
Prenatal Stress	1	2
Stress	1	2
Wi-Fi Radiation	1	1

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:5865697. Epub 2020 Jan 19. PMID: 32051687

Article Published Date : Dec 31, 2019

Study Type : Meta Analysis, Review

Additional Links

Diseases : Depression

Therapeutic Actions : Acupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Adopting an anti-inflammatory diet may be an effective intervention or preventative means of reducing depression risk and symptoms.Nov 19, 2018

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Pubmed Data : Clin Nutr. 2018 Nov 20. Epub 2018 Nov 20. PMID: 30502975

Article Published Date : Nov 19, 2018

Study Type : Meta Analysis, Review

Additional Links

Diseases : Depression, Inflammation

Additional Keywords : Anti-inflammatory Dietary Sources

[+]

Altering the gut-brain axis with probiotics may be an approach to improve depression severity.Sep 16, 2019

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Pubmed Data : Psychiatry Res. 2019 Sep 17:112568. Epub 2019 Sep 17. PMID: 31563280

Dose effect of psilocybin on primary and secondary depression.Sep 16, 2021

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Pubmed Data : J Affect Disord. 2021 Sep 17 ;296:26-34. Epub 2021 Sep 17. PMID: 34587546

Article Published Date : Sep 16, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Psilocybin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Effect of horticultural therapy on mental health.Jan 08, 2022

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Pubmed Data : J Psychiatr Ment Health Nurs. 2022 Jan 9. Epub 2022 Jan 9. PMID: 35000249

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Pubmed Data : J Ethnopharmacol. 2022 Feb 7:115067. Epub 2022 Feb 7. PMID: 35143936

Article Published Date : Feb 06, 2022

Study Type : Meta Analysis, Review

Additional Links

Substances : Paeoniflorin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Evidence suggests beneficial therapeutic effects of forest-based interventions on hypertension, stress, and mental-health disorders.Jan 10, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Is electroacupuncture an effective and safe treatment for poststroke depression?Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2021 ;2021:8661162. Epub 2021 Aug 24. PMID: 34485527

Article Published Date : Dec 31, 2020

Study Type : Meta Analysis, Review

Additional Links

Diseases : Depression, Stroke

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Kava is an effective treatment alternative to pharmaceuticals in non-psychotic anxiety disorders.Mar 01, 2005

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Pubmed Data : Phytother Res. 2005 Mar;19(3):183-8. PMID: 15934028

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Pubmed Data : Complement Ther Med. 2011 Dec ;19(6):332-48. Epub 2011 Sep 22. PMID: 22036525

Article Published Date : Dec 01, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Depression

Therapeutic Actions : Music

Pharmacological Actions : Antidepressive Agents

[+]

Meta-analysis: Saffron (Crocus sativus L.) has value in treating major depressive disorder.Oct 31, 2013

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Pubmed Data : J Integr Med. 2013 Nov ;11(6):377-83. PMID: 24299602

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neuropsychiatr Dis Treat. 2018 ;14:1297-1305. Epub 2018 May 21. PMID: 29849461

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2021 Aug 8 ;91:153699. Epub 2021 Aug 8. PMID: 34419735

Article Published Date : Aug 07, 2021

Study Type : Meta Analysis

Additional Links

Substances : Saffron

Diseases : Depression, Hypertension

Pharmacological Actions : Antidepressive Agents, Antihypertensive Agents, Hypoglycemic Agents

[+]

The effect of ginsenosides on depression in preclinical studies.Apr 30, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Psychol Res Behav Manag. 2019 ;12:297-305. Epub 2019 Apr 23. PMID: 31118846

Article Published Date : Dec 31, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Fluoxetine (trade name Prozac)

[+]

The findings suggest potentially beneficial effect of Qigong exercise on symptoms of anxiety among individuals with drug abuse.May 28, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : PLoS One. 2015;10(10):e0138904. Epub 2015 Oct 7. PMID: 26445247

Article Published Date : Dec 31, 2014

Study Type : Meta Analysis

Additional Links

Diseases : Depression, Oxidative Stress

[+]

There are high rates of behavioral symptoms in breast cancer survivors, particularly those treated with chemotherapyAug 08, 2011

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Pubmed Data : J Clin Oncol. 2011 Aug 8. Epub 2011 Aug 8. PMID: 21825266

Article Published Date : Aug 08, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Chemotherapy-Induced Toxicity, Depression, Fatigue, Inflammation, Insomnia

Anti Therapeutic Actions : Chemotherapy

Problem Substances : Chemotherapy

Adverse Pharmacological Actions : Inflammatory, Tumor necrosis factorα (TNFα) up-regulation

[+]

There is a greater incidence of depression with hypnotic use than with placebo.Jan 01, 2007

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Pubmed Data : BMC Psychiatry. 2007;7:42. Epub 2007 Aug 21. PMID: 17711589

Article Published Date : Jan 01, 2007

Study Type : Meta Analysis

Additional Links

Diseases : Depression

Problem Substances : Eszopiclone, Hypnotic Drugs, Ramelteon, Zaleplon, Zolpidem (trade name Ambien)

[+]

There is general support for antidepressant and anxiolytic effects of probiotics.Apr 16, 2019

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Pubmed Data : Neurosci Biobehav Rev. 2019 Apr 17 ;102:13-23. Epub 2019 Apr 17. PMID: 31004628

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Pubmed Data : J Psychopharmacol. 2020 May 25:269881120919957. Epub 2020 May 25. PMID: 32448048

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Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:2112359. Epub 2022 Apr 7. PMID: 35432561

Article Published Date : Dec 31, 2021

Study Type : Animal Study, Human Study

Additional Links

Substances : Flavonoids

Diseases : Depression, Infertility: Male, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Long-term exposure to ambient air pollution was identified as a risk factor for depression onset.Jan 14, 2022

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Pubmed Data : Sci Total Environ. 2022 Jan 15 ;804:149986. Epub 2021 Sep 4. PMID: 34798713

Article Published Date : Jan 14, 2022

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Depression

Additional Keywords : Risk Factors

[+]

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.Jan 01, 2009

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Pubmed Data : PLoS One. 2016 ;11(5):e0154195. Epub 2016 May 6. PMID: 27152523

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Pubmed Data : Environ Int. 2018 12 ;121(Pt 1):721-727. Epub 2018 Oct 12. PMID: 30321847

Article Published Date : Jan 11, 2018

Study Type : Human Study

Additional Links

Diseases : Depression, Mood Disorders

Therapeutic Actions : Exercise, Exercise: Cycling, Exercise: Green

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Acupressure can reduce depression and anxiety among older adults in long-term care institutions.Sep 09, 2020

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Pubmed Data : Geriatr Nurs. 2020 Sep 10. Epub 2020 Sep 10. PMID: 32921508

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Pubmed Data : Acupunct Med. 2015 Apr ;33(2):98-102. Epub 2015 Jan 16. PMID: 25595195

Article Published Date : Mar 31, 2015

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Pubmed Data : J Psychiatr Res. 2016 Sep 16 ;84:18-26. Epub 2016 Aug 16. PMID: 27693978

Article Published Date : Sep 15, 2016

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Acupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Acupuncture was associated with a significantly greater improvement in depression, pain, and physical and mental health functioning.Nov 30, 2014

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Pubmed Data : Med Care. 2014 Dec ;52(12 Suppl 5):S57-64. PMID: 25397825

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Pubmed Data : Psychiatry Res. 2018 Dec 31 ;272:467-473. Epub 2018 Dec 31. PMID: 30611966

Article Published Date : Dec 30, 2018

Study Type : Human Study

Additional Links

Substances : Fish, Fruit: All, Vegetables: All

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Adherence to a Mediterranean diet is associated with lower depressive symptoms among U.S. adults.Jan 10, 2022

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Pubmed Data : PLoS One. 2017 ;12(3):e0173869. Epub 2017 Mar 16. PMID: 28301561

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Yoga

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

[+]

Anxiety and depression are characterized by enhanced nitro-oxidative stress, lipid peroxidation, and lowered lipid-associated antioxidant defenses.May 06, 2018

Article Published Date : Nov 30, 2017

Study Type : Human Study

Additional Links

Substances : Lavender: Essential Oil

Diseases : Anxiety, Coronary Artery Disease, Depression

Therapeutic Actions : Aromatherapy Massage

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Aromatherapy massage with lavender, chamomile, and rosemary oils is effective in significantly reducing anxiety and depression.Feb 28, 2022

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Pubmed Data : Int J Ther Massage Bodywork. 2022 Mar ;15(1):37-45. Epub 2022 Mar 2. PMID: 35280245

Baduanjin is an effective intervention for improving physical and psychological health outcomes among breast cancer survivors.Mar 31, 2019

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Pubmed Data : Eur J Oncol Nurs. 2019 Apr ;39:90-97. Epub 2019 Feb 2. PMID: 30850143

Article Published Date : Mar 31, 2019

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Depression

Therapeutic Actions : Qigong

Pharmacological Actions : Antidepressive Agents

[+]

Beneficial effect of adjunct yoga therapy in depressive disorders.Oct 31, 2019

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Pubmed Data : Indian J Psychiatry. 2019 Nov-Dec;61(6):592-597. PMID: 31896865

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Diseases : Anxiety, Depression

Therapeutic Actions : Yoga

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

[+]

Brief mindfulness training reduces salivary IL-6 and TNF-α in young women with depressive symptomatology.Sep 30, 2016

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Pubmed Data : J Clin Psychiatry. 2011 Jul ;72(7):986-93. Epub 2011 Apr 5. PMID: 21535997

Article Published Date : Jun 30, 2011

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Light Therapy

Pharmacological Actions : Antidepressive Agents

[+]

Chamomile may provide clinically meaningful antidepressant activity that occurs in addition to its previously observed anxiolytic activity.Aug 31, 2012

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Pubmed Data : Altern Ther Health Med. 2012 Sep-Oct;18(5):44-9. PMID: 22894890

Article Published Date : Aug 31, 2012

Study Type : Human Study

Additional Links

Substances : Chamomile

Diseases : Anxiety Disorders, Depression

Pharmacological Actions : Antidepressive Agents, Anxiolytic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Chan-Chuang qigong improves exercise capacity, depression, and quality of life in patients with heart failure.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):505-516. PMID: 31763210

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Crocin

Diseases : Anxiety, Burning Mouth Syndrome, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Crocus sativus compares favorably in the treatment of mild to moderate depression. Feb 27, 2005

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Pubmed Data : J Ethnopharmacol. 2005 Feb 28 ;97(2):281-4. Epub 2005 Jan 6. PMID: 15707766

Article Published Date : Feb 27, 2005

Study Type : Human Study

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs, Phytotherapy, Plant Extracts

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.Jul 31, 2015

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Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

Click here to read the entire abstract

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Pubmed Data : BMC Psychiatry. 2017 Jan 14 ;17(1):15. Epub 2017 Jan 14. PMID: 28088202

Article Published Date : Jan 13, 2017

Study Type : Human Study

Additional Links

Substances : Fruit: All

Diseases : Depression

Additional Keywords : Risk Reduction

[+]

Daily supplementation with a hops dry extract can significantly improve mild depression, anxiety and stress symptoms.Mar 31, 2017

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Pubmed Data : Hormones (Athens). 2017 Apr ;16(2):171-180. PMID: 28742505

Article Published Date : Mar 31, 2017

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Pubmed Data : J Hand Surg Am. 2018 Jan 3. Epub 2018 Jan 3. PMID: 29305236

Article Published Date : Jan 02, 2018

Study Type : Human Study

Additional Links

Diseases : Carpal Tunnel Syndrome, Depression

Additional Keywords : Risk Factors

[+]

Depression risk decreases with increasing caffeinated coffee consumption. Sep 25, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arch Intern Med. 2011 Sep 26 ;171(17):1571-8. PMID: 21949167

Article Published Date : Sep 25, 2011

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Depression scores were significantly lower among nut consumers and particularly walnut consumers.Jan 25, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Jan 26 ;11(2). Epub 2019 Jan 26. PMID: 30691167

Article Published Date : Jan 25, 2019

Study Type : Human Study

Additional Links

Substances : Nuts, Walnut

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Depressive symptoms were positively associated with e-cig use in both cross-sectional and longitudinal analyses with a dose-dependent relationship.Oct 15, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Addict Behav. 2018 Oct 16 ;90:85-91. Epub 2018 Oct 16. PMID: 30368023

Article Published Date : Oct 15, 2018

Study Type : Human Study

Additional Links

Diseases : Depression

Additional Keywords : Increased Risk

Problem Substances : Electronic Cigarettes

[+]

Dietary antioxidants and fiber intake and depressive symptoms in Iranian adolescent girls.Nov 30, 2020

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Pubmed Data : Public Health Nutr. 2020 Dec 1:1-18. Epub 2020 Dec 1. PMID: 33256873

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Effects of vitamin D supplementation on depression and some involved neurotransmitters.May 14, 2020

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Pubmed Data : J Affect Disord. 2020 May 15 ;269:28-35. Epub 2020 Mar 13. PMID: 32217340

Article Published Date : May 14, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Effects of vitamin D supplementation on depression.Nov 10, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Acupunct Med. 2022 Mar 2:9645284221077104. Epub 2022 Mar 2. PMID: 35232229

Article Published Date : Mar 01, 2022

Study Type : Human Study

Additional Links

Diseases : Depression, Stroke

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Electroacupuncture combined with probiotics brings good efficacy to patients with depression and chronic diarrhea.Oct 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2019 Nov ;18(5):3470-3474. Epub 2019 Sep 6. PMID: 31602222

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Depression, Diarrhea

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Electroacupuncture is superior to fluoxetine (Prozac) in improving the TH1/TH2 cytokine ratios in depressed patients. Sep 01, 2009

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Pubmed Data : Pharmacopsychiatry. 2009 Sep;42(5):182-8. Epub 2009 Sep 1. PMID: 19724980

Click here to read the entire abstract

Pubmed Data : Taehan Kanho Hakhoe Chi. 2008 Aug ;38(4):493-502. PMID: 18753801

Article Published Date : Jul 31, 2008

Study Type : Human Study

Additional Links

Substances : Bergamot, Frankincense, Lavender

Diseases : Anxiety Disorders, Depression, Pain

Therapeutic Actions : Aromatherapy Massage

[+]

Exercise programs had positive effects in reducing the severity of depression in heart failure patients.Jul 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Lipids Health Dis. 2015 ;14(1):51. Epub 2015 May 26. PMID: 26007632

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Fish, Polyunsaturated Fatty Acids (PUFAs)

Diseases : Depression

Additional Keywords : Risk Reduction

[+]

Flavonoid-rich orange juice intake and altered gut microbiome in young adults with depressive symptoms.Jun 17, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X17748744. PMID: 29405761

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Diseases : Depression, Fatigue, Multiple Sclerosis

Therapeutic Actions : Guided Imagery

Pharmacological Actions : Antidepressive Agents

[+]

Guided imagery: reducing anxiety, depression, and selected side effects associated with chemotherapy.Sep 30, 2019

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Pubmed Data : Clin J Oncol Nurs. 2019 Oct 1 ;23(5):E87-E92. PMID: 31538976

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Neuropsychopharmacol. 2005 Jun ;8(2):215-21. Epub 2004 Sep 30. PMID: 15458612

Article Published Date : May 31, 2005

Additional Keywords : Plant Extracts

[+]

Intake of coffee associated with decreased depressive symptoms among elderly Japanese women: a multi-center cross-sectional study.Jun 21, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Epidemiol. 2019 Jun 22. Epub 2019 Jun 22. PMID: 31231097

Article Published Date : Jun 21, 2019

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Intake of raw fruits and vegetables is associated with better mental health than intake of processed fruits and vegetables.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Loneliness: A signature mental health concern in the era of COVID-19.Dec 31, 2019

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Pubmed Data : Psychiatry Res. 2020 08 ;290:113117. Epub 2020 May 23. PMID: 32480121

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Diseases : Depression, Suicidal Ideation

Additional Keywords : Increased Risk, Loneliness, Social Isolation, Stay-at-home orders

[+]

Long distance ski racing is associated with lower long-term incidence of depression in a population based, large-scale study.Aug 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Psychiatry Res. 2019 Aug 31 ;281:112546. Epub 2019 Aug 31. PMID: 31622872

Article Published Date : Aug 30, 2019

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Exercise

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Physical Activity, Risk Reduction

[+]

Long-term mindfulness practice may be associated with cognitive and functional improvements for older adults with mild cognitive impairment.Dec 01, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Aging Dis. 2016 Dec ;7(6):687-690. Epub 2016 Dec 1. PMID: 28053818

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Depression, Magnesium Deficiency, Stroke: Attenuation/Recovery

Additional Keywords : Risk Factors

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View the Evidence: 1421 Abstracts with Depression Research

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Aerobic and resistance exercises were effective in improving global cognitive function.Nov 16, 2022

Dietary intake of carotenoids and risk of depressive symptoms.Nov 06, 2022

Effectiveness and safety of electroacupuncture for depression.Dec 31, 2021

Effects of lavender on anxiety, depression, and physiological parameters.Nov 30, 2021

Efficacy of prenatal yoga in the treatment of depression and anxiety during pregnancy.Jan 27, 2022

Impacts of acupressure treatment on depression.Jan 18, 2022

Psychedelic therapy for depressive symptoms: A systematic review and meta-analysis.Oct 05, 2022

Tai Chi and qigong for depressive symptoms in patients with chronic heart failure.Dec 31, 2020

The therapeutic effect of exogenous melatonin on depressive symptoms.Dec 31, 2021

These findings suggest that green tea consumption reduces the risk of depression symptoms.Dec 31, 2021

These findings suggest that inflammation could be relevant to a large number of patients with depression.Jun 30, 2019

A meta-analysis of exercise intervention for late-life depression.Jan 20, 2020

A meta-analysis of placebo-controlled trials of psychedelic-assisted therapy.Jun 11, 2020

A regular dose of gardening can improve public health.Feb 28, 2017

Acupuncture for perimenopausal depression is safe and effective. Dec 31, 2019

Adopting an anti-inflammatory diet may be an effective intervention or preventative means of reducing depression risk and symptoms.Nov 19, 2018

Altering the gut-brain axis with probiotics may be an approach to improve depression severity.Sep 16, 2019

Antidepressants do not seem to offer a clear advantage for children and adolescents.Jun 06, 2016

Assessing the effects of methodological differences on outcomes in the use of psychedelics in the treatment of anxiety and depressive disorders.Sep 13, 2021

Continuous use of folic acid during pregnancy may reduce the incidence of perinatal depressive symptoms.Jan 19, 2022

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Current evidence supports adjunctive use of SAMe, methylfolate, omega-3, and vitamin D with antidepressants to reduce depressive symptoms.Apr 25, 2016

Data from human trials provides evidence for the efficacy of use of bright light therapy when used as augmentation to standard antidepressants.Oct 19, 2016

DHEA may be one more effective alternative between the drugs used in the treatment of depression.Aug 16, 2018

Dietary interventions hold promise as a novel intervention for reducing symptoms of depression.Feb 04, 2019

Dietary magnesium intake was significantly associated with a reduced risk of depression.Feb 28, 2017

Dose effect of psilocybin on primary and secondary depression.Sep 16, 2021

Effect of horticultural therapy on mental health.Jan 08, 2022

Effectiveness of Tai Chi for health promotion for adults with health conditions: a scoping review of Meta-analyses.Feb 17, 2020

Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.Sep 01, 2019

Efficacy of paeoniflorin on models of depression.Feb 06, 2022

Evidence suggests beneficial therapeutic effects of forest-based interventions on hypertension, stress, and mental-health disorders.Jan 10, 2021

Fruit and vegetable consumption might be inversely associated with the risk of depression.Sep 29, 2015

Greater reductions in depressive symptoms were associated with higher frequency of yoga sessions per week.May 17, 2020

High intake of dietary fiber was protectively associated with depression in adults, in a dose-response fashion.Jan 31, 2023

Hyperbaric oxygen therapy is effective and safe therapeutic approach for post-stroke depression.May 15, 2020

Impact of physical exercise on children with attention deficit hyperactivity disorders.Oct 31, 2019

Is electroacupuncture an effective and safe treatment for poststroke depression?Dec 31, 2020

Kava is an effective treatment alternative to pharmaceuticals in non-psychotic anxiety disorders.Mar 01, 2005

Massage therapy is significantly associated with alleviated depressive symptoms.Jul 01, 2010

Meditation appears to be effective for PTSD and depression symptoms.Aug 17, 2016

Meta-analysis: music listening is effective in reducing depressive symptoms in adults.Dec 01, 2011

Meta-analysis: Saffron (Crocus sativus L.) has value in treating major depressive disorder.Oct 31, 2013

Physical exercise is an effective intervention for depression. May 19, 2016

Pilates resulted in significant reductions in depressive and anxiety symptoms.Mar 31, 2018

Proprioceptive exercise may improve functional capacity, anxiety, and depression in diabetic neuropathy patients.Apr 15, 2020

Psilocybin as a new approach to treat depression and anxiety in the context of life-threatening diseases.Sep 04, 2020

Qigong can improve the self-rating depression scale and self-rating anxiety scale scores of chronic obstructive pulmonary disease patients.Apr 30, 2019

Qigong exercise may be an option for older adults to improve physical ability, functional ability, balance and to lessen depression and anxiety.Dec 31, 2018

Qigong-based exercises may be effective for alleviating depression symptoms in individuals with major depressive disorder.Jan 06, 2019

Saffron could be an effective intervention for symptoms of depression and anxiety.May 27, 2019

Saffron could be considered as an alternative to synthetic antidepressants in the treatment of mild to moderate depression.Jan 06, 2020

Saffron could be considered as an alternative to synthetic antidepressants in the treatment of mild to moderate depression.Mar 31, 2020

Saffron has a significant effect on the severity of depression.Jul 22, 2018

Saffron was effective in the treatment of major depressive disorder and had comparable efficacy to synthetic antidepressants.Dec 31, 2017

Saffron, as an adjunct therapy, contributes to relieve depression symptoms: An umbrella meta-analysis.Oct 28, 2021

Tai Chi Chuan is a worthy complementary non-pharmacological resource towards depression and anxiety.Aug 20, 2019

The available evidence indicates that saffron is a safe plant for administration as a medicine and can improve diverse clinical outcomes.Aug 07, 2021

The effect of ginsenosides on depression in preclinical studies.Apr 30, 2021

The evidence does not support definitive conclusions regarding the benefits of antidepressants for depression in adults.Jun 26, 2019

The experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysis.Jan 01, 2020

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

The findings suggest potentially beneficial effect of Qigong exercise on symptoms of anxiety among individuals with drug abuse.May 28, 2020

The present analysis supports the hypothesis that dietary n-3 PUFA intake are associated with lower risk of depression.Aug 15, 2016

The results confirm the efficacy of the three herbal active substances in elderly patients with anxiety, depression, and dementia.Jun 19, 2015

The serum TAC, paraoxonase and antioxidant levels are lower, and the serum free radical and oxidative damage product levels are higher in depressed patients.Dec 31, 2014

There are high rates of behavioral symptoms in breast cancer survivors, particularly those treated with chemotherapyAug 08, 2011

There is a greater incidence of depression with hypnotic use than with placebo.Jan 01, 2007

There is general support for antidepressant and anxiolytic effects of probiotics.Apr 16, 2019

These findings support the hypothesis of an association between long-term particulate matter exposure and depression.Jan 11, 2019

Depression

View the Evidence:
1421 Abstracts with Depression Research