Depression

Name	AC	CK
Psilocybin	73	416
Saffron	39	364
Vitamin D	43	346
Ayahuasca	42	255
Psychedelics:All	43	189
Curcumin	34	186
Probiotics	33	159
Omega-3 Fatty Acids	18	138
Flavonoids	39	131
Fruit: All	11	112
Ginsenosides	39	111
Magnesium	10	93
Lavender	9	84
Vegetables: All	8	82
Green Tea	10	60
Homeopathic Medicine: All	6	60
St. John's Wort	5	60
Vitamin C	13	58
Ginkgo biloba	10	56
Paeoniflorin	19	55
Fiber	5	53
Rosemary	11	53
DHA (Docosahexaenoic Acid)	5	52
EPA (Eicosapentaenoic Acid)	5	52
Lysergic Acid Diethylamide (LSD)	19	49
Crocin	16	46
Carotenoids	5	45
Lemon Balm	6	44
Melatonin	14	43
Chamomile	5	42
Rhodiola (Tibetan Ginseng)	5	42
Vitamin B-12	5	41
5-HTP (5-Hydroxytryptophan)	3	40
Vitamin B-6	4	40
Coenzyme Q10	6	36
Lavender: Essential Oil	5	36
Polyunsaturated Fatty Acids (PUFAs)	6	36
Ashwagandha	6	34
Black Tea	5	33
St. Johns Wort	7	33
Coffee	4	32
S-Adenosylmethionine (SAMe)	5	32
Fish	3	30
Kava Kava	2	30
Lactobacillus plantarum	3	30
NAC (N-acetyl-L-cysteine)	7	30
Palmitoylethanolamide	8	30
SAMe (S-adenosylmethionine)	2	30
Tryptophan	3	30
Indian Mulberry	5	29
Oligosaccharides	5	29
Cannabidiol	17	28
Rose	7	28
Blueberry	6	27
Berberine	13	25
Folic Acid	4	25
Chlorella (Algae)	3	22
Citicoline	3	22
Docosahexaenoic acid (DHA)	2	22
Eicosapentaenoic acid (EPA)	2	22
Fish Oil	3	22
Lion's Mane (Hericium Erinaceus)	9	22
Orange	3	22
Acetyl-l-carnitine	2	20
Bergamot	2	20
Dehydroepiandrosterone (DHEA)	1	20
Echium amoenum	2	20
Inositol	1	20
Olive Oil	2	20
Piperine	6	20
Riboflavin (Vitamin B-2)	2	20
Soy	2	20
Vitamin E	2	20
Yoghurt	2	20
Garlic	5	18
Bacopa	10	17
Fenugreek	6	17
Luteolin	9	17
Peony	7	15
Quercetin	8	15
Alpha-Lipoic Acid	3	14
Bifidobacterium Longum	3	14
Hesperidin	7	14
Lactobacillus reuteri	3	14
Magnolia	3	14
Mulberry	8	14
Prebiotics	5	14
Reishi Mushroom	8	14
Theanine	3	14
Ferulic acid	8	13
Arginine	2	12
Bee Propolis	2	12
Dandelion	2	12
Goji	2	12
Lactobacillus probiotics	2	12
Lutein	2	12
Motherwort	2	12
Polyphenols	8	12
Vitamin K2	2	12
Zinc	2	12
Cocoa	2	11
Cysteine (see N-Acetylcysteine)	2	11
Frankincense	2	11
Harmine	2	11
Honokiol	6	11
Magnolol	6	11
Nuts	2	11
Seaweed	2	11
Thymoquinone	6	11
Walnut	2	11
Apigenin	5	10
B-Carotene	1	10
Beet	1	10
Blue-Green Algae	1	10
Celery seed	1	10
Chocolate	1	10
Choline	1	10
DHEA (Dehydroepiandrosterone)	1	10
Essential Fatty Acids	1	10
Eucalyptus	1	10
Hops	1	10
Lactobacillus rhamnosus	5	10
Maca	1	10
Marjoram	1	10
Naringenin	5	10
Niacin	1	10
Omega-6 Fatty Acids	1	10
Piperidines	1	10
Resveratrol	6	10
Safflower	5	10
Selenium	1	10
Sunflower Seeds	1	10
Tea: Oolong	1	10
Thymus Extract	1	10
Vinegar	1	10
Vitamin B-3 (Niacin)	1	10
Vitamin B-5 (Pantothenic Acid)	1	10
White Tea	1	10
Puerarin	5	9
Anise	4	8
Astaxanthin	4	8
Chlorogenic Acid	4	8
Moringa oleifera	4	8
Perillaldehyde	4	8
Pomegranate	5	8
Chrysin	4	7
Gastrodin	4	7
Hyperforin	4	7
Icariin	4	7
Poria cocos	4	7
Arctigenin	3	6
Banana	3	6
Beta-Caryophyllene	3	6
Black Pepper	3	6
Butterfly Pea	3	6
Caffeine	3	6
Crocetin	3	6
Ginseng	3	6
Ginseng (Korean)	3	6
Gotu Kola	3	6
Lactobacillus paracasei	3	6
Lactoferrin	3	6
Passion Flower	4	6
Patchouli	3	6
Perilla	4	6
Raspberry	3	6
Rutin	3	6
Seaweed: Brown	3	6
Silymarin	3	6
Sulforaphane	3	6
Tanshinone IIA	3	6
Ursolic Acid	4	6
Cordyceps Militaris	3	5
Leonurine	3	5
Mucuna pruriens (aka Velvet Beans)	3	5
Onion	3	5
Valerian	3	5
Allicin	2	4
Andrographolide	2	4
Asparagus	2	4
Astragaloside	2	4
Bamboo	2	4
Bifidobacterium	2	4
Burdock	2	4
Citrus naringin	2	4
Coconut Husk/Fiber	2	4
Echinacea	2	4
Ellagic Acid	2	4
Flaxseed	2	4
Gallic Acid	2	4
Gardenia	2	4
Genipin	2	4
Geraniol	2	4
Ginger	2	4
Grape Seed Extract	2	4
Hawthorn	2	4
Honeysuckle	2	4
Hydrogen: Molecular	2	4
Hydroxytyrosol	2	4
Kefir	2	4
Krill	2	4
Lactobacillus helveticus	2	4
Lemon	2	4
Liquiritigenin	2	4
Lotus	2	4
Mango	2	4
Nicotinamide Mononucleotide	2	4
Organosulfur Compounds	2	4
Paeonol	2	4
Panax Notoginseng	3	4
Propolis: Bee	2	4
Pterostilbene	2	4
Pumpkin Seeds	2	4
Rosemaric Acid	2	4
Royal Jelly	2	4
Saikosaponin	2	4
Salvia divinorum	3	4
Sesamin	2	4
Sesamol	2	4
Silibinin	2	4
Sinomenine	2	4
Xanthohumol	2	4
Anthocyanins	2	3
Bael	2	3
Baicalein	2	3
Cannabinoids	2	3
Cannabis	2	3
Carnosic Acid	2	3
Catechin	2	3
Cordyceps sinensis	2	3
Corn Silk	2	3
Dogwood	2	3
EGCG (Epigallocatechin gallate)	2	3
Formononetin	2	3
Genistein	2	3
Huperzine	2	3
Mangiferin	2	3
Myricetin	2	3
Nigella sativa (aka Black Seed)	2	3
Oleuropein	2	3
Quince	2	3
Sea buckthorn	2	3
Syrian rue	2	3
Tualang Honey	2	3
18β-Glycyrrhetinic Acid	1	2
6-Shogaol	1	2
Andrographis	1	2
Angelica	1	2
Apocynin	1	2
Apple	1	2
Apple Polyphenols	1	2
Asiatic Acid	1	2
Astragalus	1	2
Bai Zhu	1	2
Banana Stem	1	2
Basil	1	2
Beta-glucan	1	2
Bifidobacterium Infantis	1	2
Bioflavonoids	1	2
Bitter Orange	1	2
Bixin	1	2
Blackberry	1	2
Broccoli Sprouts	1	2
Carvacrol	1	2
Cashew	1	2
Catuaba	1	2
Celery	1	2
Celery Oil	1	2
Chia	1	2
Chokeberry	1	2
Chrysanthemum Morifolium	1	2
Cinnamon	1	2
Coconut Oil	1	2
Coconut Water	1	2
Common bean	1	2
Cucurbitacin B	1	2
Curry Leaves	1	2
D-Limonene	1	2
Delta-tetrahydrocannabinol (THC)	1	2
Dill	1	2
Diosmetin	1	2
Diosmin	1	2
Elderberry	1	2
Emodin	1	2
Eriodictyol	1	2
FOS (Fructooligosaccharides)	1	2
Feijoa	1	2
Fermented Foods and Beverages	1	2
Feverfew	1	2
Fisetin	1	2
Fucoidan	1	2
Fucoxanthin	1	2
Garcinia Mangostana	1	2
Garcinia kola	1	2
Geranium	1	2
Gingerol	1	2
Goldenrod	1	2
Guava	1	2
Gynostemma	1	2
Herb Bennet	1	2
Hibiscus	1	2
Hydrogen Water	1	2
Indole-3-Carbinol	1	2
Isoflavones	1	2
Isoquercitrin	1	2
Kratom	2	2
Kudzu	1	2
Lactobacillus casei	1	2
Lactobacillus gasseri	1	2
Lactobacillus kefiranofaciens	1	2
Lactobacillus salivarius	1	2
Lemon Verbena	1	2
Lettuce	1	2
Licorice	1	2
Lignan	1	2
Ligustrazine	1	2
Lobelia	1	2
Loquat	1	2
Medicinal Mushrooms	1	2
Mimosa pudica	1	2
Musk (Animal)	1	2
Neem	1	2
Nettle	1	2
Noni	1	2
Nutmeg	1	2
Okra	1	2
Olive leaf extract	1	2
Orange: Mandarin	1	2
P-Coumaric Acid	1	2
Panax Ginseng	1	2
Parsley	1	2
Persimmon	1	2
Phloretin	1	2
Piperlongumine	1	2
Punicalagin	1	2
Pycnogenol (Pine Bark)	1	2
Radish	1	2
Red Sage	1	2
Safranal	1	2
Sage	1	2
Salvia miltiorrhiza	1	2
Schisandra	1	2
Scopoletin	1	2
Shikonin	1	2
Shitake Mushroom	1	2
Skullcap: Chinese	2	2
Spinach	1	2
Spirulina	1	2
Strawberry	1	2
Tarragon	1	2
Terminalia	1	2
Tetrahydrocurcumin	1	2
Theaflavins	1	2
Thistle	1	2
Tomatidine	1	2
Tomato	1	2
Vanillic Acid	1	2
Verbena officinalis	1	2
Virgin Coconut Oil	1	2
Vitamin E: alpha tocopherol	1	2
Whey	1	2
White Mulberry	1	2
Woodfordia fruticosa	1	2
Zataria multiflora	1	2
acetyl-11-keto-beta-boswellic acid	1	2
neohesperidin	1	2
ALA (Alpha-Linolenic Acid)	1	1
Amla Fruit	1	1
Babchi	1	1
Caffeic acid phenethyl ester	1	1
Cannabichromene	1	1
Cannabigerol	1	1
Capsaicin	1	1
Carnosol	1	1
Clove	1	1
Curcumin: Degradiation byproducts	1	1
Endocannabinoids	1	1
Grape	1	1
Graviola	1	1
Kaempferol	1	1
L-Carnitine	1	1
Mangosteen	1	1
Mistletoe	1	1
Nobiletin	1	1
Oak	1	1
Oridonin	1	1
Pantothenic Acid (Vitamin B-5)	1	1
Pistachio nut	1	1
Pomelo	1	1
Rhubarb	1	1
Rosmarinic acid	1	1
Soursop	1	1
Thiamine (B-1)	1	1
Verbascoside	1	1
Xanthones	1	1
rhodiola	1	1

Name	AC	CK
Fluoxetine (trade name Prozac)	25	180
Antidepressants	9	85
Sugar Sweetened Beverages	7	80
Sertraline	6	36
Oral Contraceptives	4	33
Selective Serotonin Reuptake Inhibitors (SSRIs)	3	22
Chemotherapy	1	20
Energy Drinks	2	20
Eszopiclone	1	20
Hypnotic Drugs	1	20
Ramelteon	1	20
Statin Drugs	2	20
Zaleplon	1	20
Zolpidem (trade name Ambien)	1	20
Bisphenol A	5	17
Glyphosate	5	17
Simvastatin	2	11
Analgesic: Non-opioid	1	10
Aspirin	1	10
Clozapine	1	10
Electronic Cigarettes	1	10
Fenofibrates	1	10
Fried Foods	1	10
Gliadin	1	10
Hydrocarbons	1	10
Nicotine	1	10
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	10
Phthalates	1	10
Proton-Pump Inhibitors	1	10
Tobacco: Smoking	1	10
Tricresyl phosphates (TCPs)	1	10
Lead	2	4
Nano Plastic-and Micro-Particles	2	4
Pesticides	2	4
Polystyrene nanoparticles	2	4
Sodium Fluoride	2	4
Dexamethasone	2	3
Oseltamivir (trade name Tamiflu)	1	3
Ozempic	1	3
Paroxetine (trade names Seroxat, Paxil)	1	3
Acrylamide	1	2
Aluminum	1	2
Antibiotics	1	2
Arsenic	1	2
Bisphenol F	1	2
Concanavalin A	1	2
Monosodium Glutamate (MSG)	1	2
Prescription Drugs	1	2
Titanium Dioxide	1	2

Name	AC	CK
Exercise	58	466
Yoga	48	436
Acupuncture	29	289
Qigong	19	236
Tai Chi	18	206
Mindfullness Training	21	185
Meditation	21	177
Electroacupuncture	30	144
Acupressure	9	103
Horticultural Therapy (Gardening)	8	100
Integrative Medicine	7	90
Exercise: Aerobic	9	85
Music	9	85
Light Therapy	7	71
Shinrin-yoku (taking in the atmosphere of the forest)	7	62
Aromatherapy Massage	6	51
Photobiomodulation	14	44
Emotional Freedom Technique	5	41
Exercise: Cycling	5	41
Exercise: Green	5	41
Hyperbaric Treatment	2	40
Massage/Therapeutic Touch	3	40
Pilates	3	40
Sunlight exposure	4	40
Therapeutic Breathing	4	40
Yogic Technique: Sudarshan kriya	6	33
Aromatherapy	4	31
Guided Imagery	4	31
Cryotherapy	3	30
Dancing	2	30
Dietary Modification: Low Carbohydrate/Ketogenic	13	27
Exercise: Running	3	25
Exercise: Resistance Training	3	22
Laughter/Humor	4	22
Art Therapy	3	21
Dietary Modification: Mediterranean Diet	3	21
Acupressure: Auricular	2	20
Cognitive Behavioural Approaches	2	20
Hydrotherapy	2	20
Mind-Body Therapies	1	20
Placebo Effect	2	20
Pulsed EMF field (PEMF)	2	20
Thermal Therapy: Far-Infrared	2	20
Magnet Therapy	3	12
Exercise: HIIT	2	11
Behavioral Treatment	1	10
Color Therapy	1	10
Dietary Modification: Vegetarian	1	10
Homeopathic Treatment	1	10
Hormone Replacement Therapy	1	10
Hypnosis	1	10
Light Therapy: Red Colored	1	10
Mantra	1	10
Positive Mood	1	10
Prevent Pain	1	10
Reiki Therapy	1	10
Sauna Therapy	1	10
Sound Therapy	1	10
Whole-Body Vibration	1	10
Yogic Breathing	1	10
Chiropractic treatment	2	4
Grounding: Contact with the Earth	2	3
Mediterranean diet	1	1
Microbiota Transfer Therapy	1	1
Ultrasound therapy	1	1

Name	AC	CK
Electroconvulsive Therapy	9	91
Western Diet	6	44
Electromagnetic Field Harms	4	23
Mobile Phone Radiation	3	21
Chemotherapy	1	20
Blue Light (400−495 nm)	3	14
Vaccination: All	2	13
Angioplasty	2	12
Electromagnetic Radiation	2	12
Air Travel	1	10
Nocebo Effect	1	10
X-ray Mammography	1	10
Vaccination: HPV (Gardasil)	1	3
Vasectomy	1	3
Prenatal Stress	1	2
Stress	1	2
Wi-Fi Radiation	1	1

[+]

[+]

These findings suggest that green tea consumption reduces the risk of depression symptoms.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2022 ;68(3):155-161. PMID: 35768246

Article Published Date : Dec 31, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Green Tea

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Yoga-based interventions may reduce anxiety symptoms in anxiety disorders and depression symptoms in depressive disorders.Jun 26, 2023

Click here to read the entire abstract

Pubmed Data : Br J Sports Med. 2023 Jun 27. Epub 2023 Jun 27. PMID: 37369553

Click here to read the entire abstract

Pubmed Data : Lancet. 2016 Jun 7. Epub 2016 Jun 7. PMID: 27289172

Article Published Date : Jun 06, 2016

Study Type : Meta Analysis

Additional Links

Diseases : Depression

Additional Keywords : Adverse Events, Risk Factors

Problem Substances : Antidepressants

[+]

Assessing the effects of methodological differences on outcomes in the use of psychedelics in the treatment of anxiety and depressive disorders.Sep 13, 2021

Click here to read the entire abstract

Pubmed Data : J Psychopharmacol. 2021 Sep 14:2698811211044688. Epub 2021 Sep 14. PMID: 34519567

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2015 Nov 27. Epub 2015 Nov 27. PMID: 26610378

Click here to read the entire abstract

Pubmed Data : J Affect Disord. 2021 Sep 17 ;296:26-34. Epub 2021 Sep 17. PMID: 34587546

Article Published Date : Sep 16, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Psilocybin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Effect of horticultural therapy on mental health.Jan 08, 2022

Click here to read the entire abstract

Pubmed Data : J Psychiatr Ment Health Nurs. 2022 Jan 9. Epub 2022 Jan 9. PMID: 35000249

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2023 Aug 25 ;102(34):e34905. PMID: 37653776

Article Published Date : Aug 24, 2023

Study Type : Meta Analysis

Additional Links

Diseases : Cognitive Decline/Dysfunction, Depression

Therapeutic Actions : Dancing, Mind-Body Therapies, Qigong, Tai Chi

Pharmacological Actions : Antidepressive Agents, Neuroprotective Agents

[+]

Effects of Tai Chi on sleep quality as well as depression and anxiety in insomnia patients.Feb 08, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Nutrition. 2015 Sep 30. Epub 2015 Sep 30. PMID: 26691768

Article Published Date : Sep 29, 2015

Study Type : Meta Analysis

Additional Links

Substances : Fruit: All, Vegetables: All

Diseases : Depression

Additional Keywords : Risk Reduction

[+]

Greater reductions in depressive symptoms were associated with higher frequency of yoga sessions per week.May 17, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2019 Nov ;98(46):e17980. PMID: 31725664

Article Published Date : Oct 31, 2019

Study Type : Meta Analysis

Additional Links

Diseases : Anxiety, Attention Deficit Hyperactivity Disorder, Depression

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

Additional Keywords : Physical Activity

[+]

Is electroacupuncture an effective and safe treatment for poststroke depression?Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2021 ;2021:8661162. Epub 2021 Aug 24. PMID: 34485527

Article Published Date : Dec 31, 2020

Study Type : Meta Analysis, Review

Additional Links

Diseases : Depression, Stroke

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Kava is an effective treatment alternative to pharmaceuticals in non-psychotic anxiety disorders.Mar 01, 2005

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2005 Mar;19(3):183-8. PMID: 15934028

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2011 Dec ;19(6):332-48. Epub 2011 Sep 22. PMID: 22036525

Article Published Date : Dec 01, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Depression

Therapeutic Actions : Music

Pharmacological Actions : Antidepressive Agents

[+]

Meta-analysis: Saffron (Crocus sativus L.) has value in treating major depressive disorder.Oct 31, 2013

Click here to read the entire abstract

Pubmed Data : J Integr Med. 2013 Nov ;11(6):377-83. PMID: 24299602

Click here to read the entire abstract

Pubmed Data : Int J Psychiatry Med. 2025 Apr 25:912174251337572. Epub 2025 Apr 25. PMID: 40279353

Article Published Date : Apr 24, 2025

Study Type : Meta Analysis

Additional Links

Substances : Psilocybin

Diseases : Anxiety, Cancers: All, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Qigong can improve the self-rating depression scale and self-rating anxiety scale scores of chronic obstructive pulmonary disease patients.Apr 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neuropsychiatr Dis Treat. 2018 ;14:1297-1305. Epub 2018 May 21. PMID: 29849461

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Psychol Res Behav Manag. 2019 ;12:297-305. Epub 2019 Apr 23. PMID: 31118846

Article Published Date : Dec 31, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Fluoxetine (trade name Prozac)

[+]

The findings suggest potentially beneficial effect of Qigong exercise on symptoms of anxiety among individuals with drug abuse.May 28, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Med Ther. 2020 May 29 ;20(1):161. Epub 2020 May 29. PMID: 32471415

Article Published Date : May 28, 2020

Study Type : Meta Analysis, Review

Additional Links

Diseases : Anxiety, Depression, Drug Abuse

Therapeutic Actions : Qigong, Tai Chi

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

The serum TAC, paraoxonase and antioxidant levels are lower, and the serum free radical and oxidative damage product levels are higher in depressed patients.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : PLoS One. 2015;10(10):e0138904. Epub 2015 Oct 7. PMID: 26445247

Article Published Date : Dec 31, 2014

Study Type : Meta Analysis

Additional Links

Diseases : Depression, Oxidative Stress

[+]

There are high rates of behavioral symptoms in breast cancer survivors, particularly those treated with chemotherapyAug 08, 2011

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Pubmed Data : J Clin Oncol. 2011 Aug 8. Epub 2011 Aug 8. PMID: 21825266

Article Published Date : Aug 08, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Chemotherapy-Induced Toxicity, Depression, Fatigue, Inflammation, Insomnia

Anti Therapeutic Actions : Chemotherapy

Problem Substances : Chemotherapy

Adverse Pharmacological Actions : Inflammatory, Tumor necrosis factorα (TNFα) up-regulation

[+]

There is a greater incidence of depression with hypnotic use than with placebo.Jan 01, 2007

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Pubmed Data : BMC Psychiatry. 2007;7:42. Epub 2007 Aug 21. PMID: 17711589

Article Published Date : Jan 01, 2007

Study Type : Meta Analysis

Additional Links

Diseases : Depression

Problem Substances : Eszopiclone, Hypnotic Drugs, Ramelteon, Zaleplon, Zolpidem (trade name Ambien)

[+]

There is general support for antidepressant and anxiolytic effects of probiotics.Apr 16, 2019

Click here to read the entire abstract

Pubmed Data : Neurosci Biobehav Rev. 2019 Apr 17 ;102:13-23. Epub 2019 Apr 17. PMID: 31004628

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Public Health. 2022 ;10:903547. Epub 2022 Aug 1. PMID: 35979473

Article Published Date : Dec 31, 2021

Study Type : Meta Analysis

Additional Links

Substances : Vitamin D

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

These results indicate a beneficial effect of the combination of EPA and DHA on depressed mood in women compared with placebo. Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Psychopharmacol. 2020 May 25:269881120919957. Epub 2020 May 25. PMID: 32448048

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Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:2112359. Epub 2022 Apr 7. PMID: 35432561

Article Published Date : Dec 31, 2021

Study Type : Animal Study, Human Study

Additional Links

Substances : Flavonoids

Diseases : Depression, Infertility: Male, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Long-term exposure to ambient air pollution was identified as a risk factor for depression onset.Jan 14, 2022

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Pubmed Data : Sci Total Environ. 2022 Jan 15 ;804:149986. Epub 2021 Sep 4. PMID: 34798713

Article Published Date : Jan 14, 2022

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Depression

Additional Keywords : Risk Factors

[+]

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.Jan 01, 2009

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Pubmed Data : PLoS One. 2016 ;11(5):e0154195. Epub 2016 May 6. PMID: 27152523

[+]

A single dose psilocybin produced rapid and enduring anxiolytic and anti-depressant effects in patients with cancer-related psychological distress.Nov 30, 2016

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Pubmed Data : J Psychopharmacol. 2016 Dec ;30(12):1165-1180. PMID: 27909164

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Cancers: All, Depression

Pharmacological Actions : Antidepressive Agents

[+]

A standardized Withania somniferra root extract with piperine alleviates the symptoms of anxiety and depression.Oct 24, 2023

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Pubmed Data : J Integr Complement Med. 2023 Oct 25. Epub 2023 Oct 25. PMID: 37878284

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Pubmed Data : Environ Int. 2018 12 ;121(Pt 1):721-727. Epub 2018 Oct 12. PMID: 30321847

Article Published Date : Jan 11, 2018

Study Type : Human Study

Additional Links

Diseases : Depression, Mood Disorders

Therapeutic Actions : Exercise, Exercise: Cycling, Exercise: Green

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Acupressure can reduce depression and anxiety among older adults in long-term care institutions.Sep 09, 2020

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Pubmed Data : Geriatr Nurs. 2020 Sep 10. Epub 2020 Sep 10. PMID: 32921508

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Pubmed Data : Acupunct Med. 2015 Apr ;33(2):98-102. Epub 2015 Jan 16. PMID: 25595195

Article Published Date : Mar 31, 2015

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Pubmed Data : J Psychiatr Res. 2016 Sep 16 ;84:18-26. Epub 2016 Aug 16. PMID: 27693978

Article Published Date : Sep 15, 2016

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Acupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Acupuncture was associated with a significantly greater improvement in depression, pain, and physical and mental health functioning.Nov 30, 2014

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Pubmed Data : Med Care. 2014 Dec ;52(12 Suppl 5):S57-64. PMID: 25397825

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Pubmed Data : Psychiatry Res. 2018 Dec 31 ;272:467-473. Epub 2018 Dec 31. PMID: 30611966

Article Published Date : Dec 30, 2018

Study Type : Human Study

Additional Links

Substances : Fish, Fruit: All, Vegetables: All

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Adherence to a Mediterranean diet is associated with lower depressive symptoms among U.S. adults.Jan 10, 2022

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Pubmed Data : Am J Epidemiol. 2024 Aug 27. Epub 2024 Aug 27. PMID: 39191648

Article Published Date : Aug 26, 2024

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Depression

[+]

Amelioration of anxiety, depression, and chemotherapy related toxicity after crocin administration during chemotherapy.Jun 23, 2021

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Pubmed Data : Phytother Res. 2021 Jun 24. Epub 2021 Jun 24. PMID: 34164855

Article Published Date : Jun 23, 2021

Study Type : Human Study

Additional Links

Diseases : Anxiety, Breast Cancer, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Chemoprotective Agents

[+]

An 8-week hatha yoga intervention resulted in statistically and clinically significant reductions in depression severity.Dec 31, 2016

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Pubmed Data : PLoS One. 2017 ;12(3):e0173869. Epub 2017 Mar 16. PMID: 28301561

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Yoga

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

[+]

Anxiety and depression are characterized by enhanced nitro-oxidative stress, lipid peroxidation, and lowered lipid-associated antioxidant defenses.May 06, 2018

Article Published Date : Nov 30, 2017

Study Type : Human Study

Additional Links

Substances : Lavender: Essential Oil

Diseases : Anxiety, Coronary Artery Disease, Depression

Therapeutic Actions : Aromatherapy Massage

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Aromatherapy massage with lavender, chamomile, and rosemary oils is effective in significantly reducing anxiety and depression.Feb 28, 2022

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Pubmed Data : Int J Ther Massage Bodywork. 2022 Mar ;15(1):37-45. Epub 2022 Mar 2. PMID: 35280245

Pubmed Data : Front Psychol. 2021 ;12:678911. Epub 2021 Aug 17. PMID: 34484035

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Magnet Therapy , Meditation

Pharmacological Actions : Antidepressive Agents

[+]

Auricular acupressure is an effective and safe treatment for alleviating symptoms of depressive and anxiety in patients with COVID-19.Dec 31, 2021

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[+]

Brief targeted mindfulness interventions can help to reduce symptoms and buffer maladaptive responses to negative mood in acutely depressed patients.Oct 11, 2017

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Pubmed Data : Behav Res Ther. 2017 Oct 12 ;99:124-130. Epub 2017 Oct 12. PMID: 29078199

Article Published Date : Oct 11, 2017

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Mindfullness Training

Pharmacological Actions : Antidepressive Agents

[+]

Bright light treatment, both as monotherapy and in combination with fluoxetine, was efficacious and well tolerated in the treatment of adults with nonseasonal Nonseasonal Major Depressive Disorder.Dec 31, 2015

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Pubmed Data : JAMA Psychiatry. 2016 Jan ;73(1):56-63. PMID: 26580307

Clinical efficacy of this herbal drug was significantly higher than citalopram.Dec 31, 2018

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Pubmed Data : Curr Drug Discov Technol. 2019 ;16(2):232-238. PMID: 29468978

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Brain Imaging Behav. 2016 Jun ;10(2):437-44. PMID: 26063438

Article Published Date : May 31, 2016

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Pubmed Data : Zhongguo Zhen Jiu. 2014 Oct ;34(10):956-60. PMID: 25543421

Article Published Date : Sep 30, 2014

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Depression

Therapeutic Actions : Acupressure: Auricular, Acupuncture

Additional Keywords : Significant Treatment Outcome , Therapeutic Action Superior to Drug Therapy

[+]

Combining therapeutic acupuncture with structured salutogenic dialogue appears to have greater intermediate-term effects than usual primary care in reducing anxiety and depression.Dec 31, 2013

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Pubmed Data : BMC Complement Altern Med. 2014 ;14:210. Epub 2014 Jun 30. PMID: 24980440

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Diseases : Anxiety Disorders, Depression, Depressive Disorder, Psychological Distress

Therapeutic Actions : Acupuncture, Integrative Medicine

[+]

Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.Jan 31, 2013

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Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):505-516. PMID: 31763210

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Crocin

Diseases : Anxiety, Burning Mouth Syndrome, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Crocus sativus compares favorably in the treatment of mild to moderate depression. Feb 27, 2005

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Pubmed Data : J Ethnopharmacol. 2005 Feb 28 ;97(2):281-4. Epub 2005 Jan 6. PMID: 15707766

Article Published Date : Feb 27, 2005

Study Type : Human Study

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs, Phytotherapy, Plant Extracts

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.Jul 31, 2015

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Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

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Pubmed Data : Phytother Res. 2015 Jan ;29(1):17-21. Epub 2014 Aug 4. PMID: 25091591

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperidines

Diseases : Anxiety Disorders, Depression, Depressive Disorder

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Depression and pain anxiety of carpal tunnel syndrome patients are associated with the symptom severity.Jan 02, 2018

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Pubmed Data : J Hand Surg Am. 2018 Jan 3. Epub 2018 Jan 3. PMID: 29305236

Article Published Date : Jan 02, 2018

Study Type : Human Study

Additional Links

Diseases : Carpal Tunnel Syndrome, Depression

Additional Keywords : Risk Factors

[+]

Depression risk decreases with increasing caffeinated coffee consumption. Sep 25, 2011

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Pubmed Data : Arch Intern Med. 2011 Sep 26 ;171(17):1571-8. PMID: 21949167

Article Published Date : Sep 25, 2011

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Depression scores were significantly lower among nut consumers and particularly walnut consumers.Jan 25, 2019

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Pubmed Data : Nutrients. 2019 Jan 26 ;11(2). Epub 2019 Jan 26. PMID: 30691167

Article Published Date : Jan 25, 2019

Study Type : Human Study

Additional Links

Substances : Nuts, Walnut

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Depressive symptoms were positively associated with e-cig use in both cross-sectional and longitudinal analyses with a dose-dependent relationship.Oct 15, 2018

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Pubmed Data : Addict Behav. 2018 Oct 16 ;90:85-91. Epub 2018 Oct 16. PMID: 30368023

Article Published Date : Oct 15, 2018

Study Type : Human Study

Additional Links

Diseases : Depression

Additional Keywords : Increased Risk

Problem Substances : Electronic Cigarettes

[+]

Dietary antioxidants and fiber intake and depressive symptoms in Iranian adolescent girls.Nov 30, 2020

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Pubmed Data : Public Health Nutr. 2020 Dec 1:1-18. Epub 2020 Dec 1. PMID: 33256873

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Avicenna J Phytomed. 2022 ;12(6):627-637. PMID: 36583177

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Beet

Diseases : Anxiety, Depression

Therapeutic Actions : Exercise: HIIT

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Effect of laser biostimulation and a low-calorie diet vs. a low-calorie diet alone on insulin resistance, inflammatory biomarkers, and depression among obese postmenopausal women.Apr 30, 2022

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Pubmed Data : BMC Complement Med Ther. 2024 May 24 ;24(1):203. Epub 2024 May 24. PMID: 38790041

Article Published Date : May 23, 2024

Study Type : Human Study

Additional Links

Diseases : Anxiety, Depression

Therapeutic Actions : Yoga

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

[+]

Effects of diaphragmatic breathing and systematic relaxation on depression, anxiety, stress, and glycemic control in type 2 diabetes mellitus.Sep 06, 2021

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Pubmed Data : Int J Yoga Therap. 2021 Sep 7. Epub 2021 Sep 7. PMID: 34491340

Article Published Date : Sep 06, 2021

Study Type : Human Study

Additional Links

Diseases : anti-anxiety, Depression, Diabetes Mellitus: Type 2

Therapeutic Actions : Therapeutic Breathing

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Hypoglycemic Agents

[+]

Click here to read the entire abstract

Pubmed Data : J Affect Disord. 2020 May 15 ;269:28-35. Epub 2020 Mar 13. PMID: 32217340

Article Published Date : May 14, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Effects of vitamin D supplementation on depression.Nov 10, 2022

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Pubmed Data : J Food Biochem. 2020 Oct 6:e13507. Epub 2020 Oct 6. PMID: 33025616

Article Published Date : Oct 05, 2020

Study Type : Human Study

Additional Links

Substances : Fenugreek

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Efficacy of Withania somnifera supplementation on adult's cognition and mood.Nov 23, 2021

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Pubmed Data : Acupunct Med. 2022 Mar 2:9645284221077104. Epub 2022 Mar 2. PMID: 35232229

Article Published Date : Mar 01, 2022

Study Type : Human Study

Additional Links

Diseases : Depression, Stroke

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Electroacupuncture combined with probiotics brings good efficacy to patients with depression and chronic diarrhea.Oct 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2019 Nov ;18(5):3470-3474. Epub 2019 Sep 6. PMID: 31602222

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Depression, Diarrhea

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Click here to read the entire abstract

Pubmed Data : Taehan Kanho Hakhoe Chi. 2008 Aug ;38(4):493-502. PMID: 18753801

Article Published Date : Jul 31, 2008

Study Type : Human Study

Additional Links

Substances : Bergamot, Frankincense, Lavender

Diseases : Anxiety Disorders, Depression, Pain

Therapeutic Actions : Aromatherapy Massage

[+]

Exercise programs had positive effects in reducing the severity of depression in heart failure patients.Jul 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Environ Res Public Health. 2016 ;13(3). Epub 2016 Feb 24. PMID: 26927141

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Diseases : Chronic Pain, Depression, Quality of Life: Poor

Therapeutic Actions : Shinrin-yoku (taking in the atmosphere of the forest)

Additional Keywords : Significant Treatment Outcome

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View the Evidence: 1776 Abstracts with Depression Research

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Acupressure exhibited a significant beneficial effect on reducing the severity of depression compared with sham acupressure.Jan 31, 2024

Acupuncture is a safe and effective complementary therapy for tumor-related depression.Dec 31, 2022

Acupuncture seems to be able to effectively improve anxiety and depression in migraine patients.Aug 03, 2023

Acupuncture, when compared to conventional pharmacotherapy, exhibits significant efficacy as a standalone treatmentDec 31, 2023

Aerobic and resistance exercises were effective in improving global cognitive function.Nov 16, 2022

Dietary intake of carotenoids and risk of depressive symptoms.Nov 06, 2022

Effectiveness and safety of electroacupuncture for depression.Dec 31, 2021

Effectiveness of acupuncture plus music therapy for post-stroke depression,Sep 12, 2024

Effects of lavender on anxiety, depression, and physiological parameters.Nov 30, 2021

Effects of mind-body therapies on depression among adolescents.Dec 31, 2023

Efficacy of ginsenoside Rg1 on rodent models of depression.Jul 22, 2024

Efficacy of prenatal yoga in the treatment of depression and anxiety during pregnancy.Jan 27, 2022

Efficacy of scalp acupuncture combined with conventional therapy in the intervention of post-stroke depression.Sep 30, 2023

Exercise is an effective treatment for depression.Feb 13, 2024

Ginkgo biloba might reduce the risk of depression or depressive symptoms with safe clinical efficacy.Dec 31, 2023

Impacts of acupressure treatment on depression.Jan 18, 2022

Psychedelic therapy for depressive symptoms: A systematic review and meta-analysis.Oct 05, 2022

Tai Chi and qigong for depressive symptoms in patients with chronic heart failure.Dec 31, 2020

Tai Chi exercise for mental and physical well-being in patients with depressive symptoms.Feb 04, 2023

The association of ultra-processed food consumption with adult mental health disorders.Sep 30, 2023

The effect of mindfulness meditation on depressive symptoms during the COVID-19 pandemic.Aug 29, 2024

The effect of Tai Chi/Qigong on depression and anxiety symptoms in adults with cancer.Apr 07, 2024

The therapeutic effect of exogenous melatonin on depressive symptoms.Dec 31, 2021

These findings suggest that green tea consumption reduces the risk of depression symptoms.Dec 31, 2021

Yoga-based interventions may reduce anxiety symptoms in anxiety disorders and depression symptoms in depressive disorders.Jun 26, 2023

These findings suggest that inflammation could be relevant to a large number of patients with depression.Jun 30, 2019

A meta-analysis of exercise intervention for late-life depression.Jan 20, 2020

A meta-analysis of placebo-controlled trials of psychedelic-assisted therapy.Jun 11, 2020

A regular dose of gardening can improve public health.Feb 28, 2017

Acupuncture for perimenopausal depression is safe and effective. Dec 31, 2019

Acupuncture improves sleep disorders and depression among patients with Parkinson's disease.Jul 16, 2023

Adopting an anti-inflammatory diet may be an effective intervention or preventative means of reducing depression risk and symptoms.Nov 19, 2018

Altering the gut-brain axis with probiotics may be an approach to improve depression severity.Sep 16, 2019

Antidepressants do not seem to offer a clear advantage for children and adolescents.Jun 06, 2016

Assessing the effects of methodological differences on outcomes in the use of psychedelics in the treatment of anxiety and depressive disorders.Sep 13, 2021

Association between air pollutants and four major mental disorders.Sep 14, 2024

Continuous use of folic acid during pregnancy may reduce the incidence of perinatal depressive symptoms.Jan 19, 2022

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Current evidence supports adjunctive use of SAMe, methylfolate, omega-3, and vitamin D with antidepressants to reduce depressive symptoms.Apr 25, 2016

Data from human trials provides evidence for the efficacy of use of bright light therapy when used as augmentation to standard antidepressants.Oct 19, 2016

Despite continuation of therapy the risk of relapse within the first year following ECT is substantial.Oct 31, 2013

DHEA may be one more effective alternative between the drugs used in the treatment of depression.Aug 16, 2018

Dietary interventions hold promise as a novel intervention for reducing symptoms of depression.Feb 04, 2019

Dietary magnesium intake was significantly associated with a reduced risk of depression.Feb 28, 2017

Dose effect of psilocybin on primary and secondary depression.Sep 16, 2021

Effect of horticultural therapy on mental health.Jan 08, 2022

Effectiveness of Tai Chi for health promotion for adults with health conditions: a scoping review of Meta-analyses.Feb 17, 2020

Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.Sep 01, 2019

Effects of mind-body exercise on cognitive performance in middle-aged and older adults with mild cognitive impairment.Aug 24, 2023

Effects of Tai Chi on sleep quality as well as depression and anxiety in insomnia patients.Feb 08, 2023

Efficacy of paeoniflorin on models of depression.Feb 06, 2022

Evidence suggests beneficial therapeutic effects of forest-based interventions on hypertension, stress, and mental-health disorders.Jan 10, 2021

Fruit and vegetable consumption might be inversely associated with the risk of depression.Sep 29, 2015

Greater reductions in depressive symptoms were associated with higher frequency of yoga sessions per week.May 17, 2020

High intake of dietary fiber was protectively associated with depression in adults, in a dose-response fashion.Jan 31, 2023

Hyperbaric oxygen therapy is effective and safe therapeutic approach for post-stroke depression.May 15, 2020

Impact of physical exercise on children with attention deficit hyperactivity disorders.Oct 31, 2019

Is electroacupuncture an effective and safe treatment for poststroke depression?Dec 31, 2020

Kava is an effective treatment alternative to pharmaceuticals in non-psychotic anxiety disorders.Mar 01, 2005

Massage therapy is significantly associated with alleviated depressive symptoms.Jul 01, 2010

Meditation appears to be effective for PTSD and depression symptoms.Aug 17, 2016

Meta-analysis: music listening is effective in reducing depressive symptoms in adults.Dec 01, 2011

Meta-analysis: Saffron (Crocus sativus L.) has value in treating major depressive disorder.Oct 31, 2013

Physical exercise is an effective intervention for depression. May 19, 2016

Pilates resulted in significant reductions in depressive and anxiety symptoms.Mar 31, 2018

Proprioceptive exercise may improve functional capacity, anxiety, and depression in diabetic neuropathy patients.Apr 15, 2020

Psilocybin as a new approach to treat depression and anxiety in the context of life-threatening diseases.Sep 04, 2020

Psilocybin may rapidly reduce depressive and anxiety symptoms in cancer patients.Apr 24, 2025

Qigong can improve the self-rating depression scale and self-rating anxiety scale scores of chronic obstructive pulmonary disease patients.Apr 30, 2019

Qigong exercise may be an option for older adults to improve physical ability, functional ability, balance and to lessen depression and anxiety.Dec 31, 2018

Depression

View the Evidence:
1776 Abstracts with Depression Research