Depression

Name	AC	CK
Psilocybin	78	431
Saffron	39	364
Vitamin D	43	346
Ayahuasca	42	255
Psychedelics:All	43	189
Curcumin	35	187
Probiotics	33	159
Flavonoids	42	138
Omega-3 Fatty Acids	18	138
Fruit: All	11	112
Ginsenosides	39	111
Magnesium	10	93
Lavender	9	84
Vegetables: All	8	82
Green Tea	11	61
Homeopathic Medicine: All	6	60
Paeoniflorin	22	60
St. John's Wort	5	60
Vitamin C	13	58
Ginkgo biloba	10	56
Fiber	5	53
Rosemary	11	53
DHA (Docosahexaenoic Acid)	5	52
EPA (Eicosapentaenoic Acid)	5	52
Lysergic Acid Diethylamide (LSD)	19	49
Crocin	17	48
Carotenoids	5	45
Lemon Balm	6	44
Melatonin	14	43
Chamomile	5	42
Rhodiola (Tibetan Ginseng)	5	42
Ashwagandha	10	41
Vitamin B-12	5	41
5-HTP (5-Hydroxytryptophan)	3	40
Vitamin B-6	4	40
Coenzyme Q10	6	36
Lavender: Essential Oil	5	36
Polyunsaturated Fatty Acids (PUFAs)	6	36
Black Tea	5	33
St. Johns Wort	7	33
Coffee	4	32
S-Adenosylmethionine (SAMe)	5	32
Fish	3	30
Kava Kava	2	30
Lactobacillus plantarum	3	30
NAC (N-acetyl-L-cysteine)	7	30
Palmitoylethanolamide	8	30
SAMe (S-adenosylmethionine)	2	30
Tryptophan	3	30
Indian Mulberry	5	29
Oligosaccharides	5	29
Cannabidiol	17	28
Rose	7	28
Blueberry	6	27
Berberine	13	25
Folic Acid	4	25
Chlorella (Algae)	3	22
Citicoline	3	22
Docosahexaenoic acid (DHA)	2	22
Eicosapentaenoic acid (EPA)	2	22
Fish Oil	3	22
Lion's Mane (Hericium Erinaceus)	9	22
Orange	3	22
Acetyl-l-carnitine	2	20
Bergamot	2	20
Dehydroepiandrosterone (DHEA)	1	20
Echium amoenum	2	20
Inositol	1	20
Olive Oil	2	20
Piperine	6	20
Riboflavin (Vitamin B-2)	2	20
Soy	2	20
Vitamin E	2	20
Yoghurt	2	20
Garlic	5	18
Bacopa	10	17
Fenugreek	6	17
Luteolin	9	17
Hesperidin	8	15
Peony	7	15
Quercetin	8	15
Theanine	4	15
Alpha-Lipoic Acid	3	14
Bifidobacterium Longum	3	14
Lactobacillus reuteri	3	14
Magnolia	3	14
Mulberry	8	14
Prebiotics	5	14
Reishi Mushroom	8	14
Safflower	7	14
Ferulic acid	8	13
Polyphenols	9	13
Thymoquinone	7	13
Arginine	2	12
Bee Propolis	2	12
Dandelion	2	12
Goji	2	12
Lactobacillus probiotics	2	12
Lutein	2	12
Motherwort	2	12
Vitamin K2	2	12
Zinc	2	12
Cocoa	2	11
Cysteine (see N-Acetylcysteine)	2	11
Frankincense	2	11
Harmine	2	11
Honokiol	6	11
Hydrogen: Molecular	7	11
Magnolol	6	11
Nuts	2	11
Seaweed	2	11
Walnut	2	11
Apigenin	5	10
B-Carotene	1	10
Beet	1	10
Blue-Green Algae	1	10
Celery seed	1	10
Chocolate	1	10
Choline	1	10
DHEA (Dehydroepiandrosterone)	1	10
Essential Fatty Acids	1	10
Eucalyptus	1	10
Hops	1	10
Lactobacillus rhamnosus	5	10
Maca	1	10
Marjoram	1	10
Naringenin	5	10
Niacin	1	10
Omega-6 Fatty Acids	1	10
Piperidines	1	10
Resveratrol	6	10
Selenium	1	10
Sunflower Seeds	1	10
Tea: Oolong	1	10
Thymus Extract	1	10
Vinegar	1	10
Vitamin B-3 (Niacin)	1	10
Vitamin B-5 (Pantothenic Acid)	1	10
White Tea	1	10
Icariin	5	9
Puerarin	5	9
Anise	4	8
Astaxanthin	4	8
Chlorogenic Acid	4	8
Gotu Kola	4	8
Hydrogen Water	4	8
Moringa oleifera	4	8
Perillaldehyde	4	8
Pomegranate	5	8
Chrysin	4	7
Gastrodin	4	7
Hyperforin	4	7
Poria cocos	4	7
Arctigenin	3	6
Banana	3	6
Beta-Caryophyllene	3	6
Black Pepper	3	6
Butterfly Pea	3	6
Caffeine	3	6
Crocetin	3	6
Ginseng	3	6
Ginseng (Korean)	3	6
Lactobacillus paracasei	3	6
Lactoferrin	3	6
Passion Flower	4	6
Patchouli	3	6
Perilla	4	6
Raspberry	3	6
Rutin	3	6
Seaweed: Brown	3	6
Silymarin	3	6
Sulforaphane	3	6
Tanshinone IIA	3	6
Ursolic Acid	4	6
Cordyceps Militaris	3	5
Leonurine	3	5
Mucuna pruriens (aka Velvet Beans)	3	5
Onion	3	5
Royal Jelly	3	5
Valerian	3	5
Allicin	2	4
Andrographolide	2	4
Asparagus	2	4
Astragaloside	2	4
Bamboo	2	4
Bifidobacterium	2	4
Burdock	2	4
Citrus naringin	2	4
Coconut Husk/Fiber	2	4
EGCG (Epigallocatechin gallate)	3	4
Echinacea	2	4
Ellagic Acid	2	4
Flaxseed	2	4
Gallic Acid	2	4
Gardenia	2	4
Genipin	2	4
Geraniol	2	4
Ginger	2	4
Grape Seed Extract	2	4
Hawthorn	2	4
Honeysuckle	2	4
Hydroxytyrosol	2	4
Kefir	2	4
Krill	2	4
Lactobacillus helveticus	2	4
Lemon	2	4
Liquiritigenin	2	4
Lotus	2	4
Mango	2	4
Nicotinamide Mononucleotide	2	4
Organosulfur Compounds	2	4
Paeonol	2	4
Panax Notoginseng	3	4
Propolis: Bee	2	4
Pterostilbene	2	4
Pumpkin Seeds	2	4
Rosemaric Acid	2	4
Saikosaponin	2	4
Salvia divinorum	3	4
Sesamin	2	4
Sesamol	2	4
Silibinin	2	4
Sinomenine	2	4
Xanthohumol	2	4
neohesperidin	2	4
Anthocyanins	2	3
Bael	2	3
Baicalein	2	3
Cannabinoids	2	3
Cannabis	2	3
Carnosic Acid	2	3
Catechin	2	3
Cordyceps sinensis	2	3
Corn Silk	2	3
Diosmin	2	3
Dogwood	2	3
Formononetin	2	3
Genistein	2	3
Huperzine	2	3
Mangiferin	2	3
Myricetin	2	3
Nigella sativa (aka Black Seed)	2	3
Oleuropein	2	3
Quince	2	3
Sea buckthorn	2	3
Syrian rue	2	3
Tualang Honey	2	3
18β-Glycyrrhetinic Acid	1	2
6-Shogaol	1	2
Andrographis	1	2
Angelica	1	2
Apocynin	1	2
Apple	1	2
Apple Polyphenols	1	2
Asiatic Acid	1	2
Astragalus	1	2
Bai Zhu	1	2
Banana Stem	1	2
Basil	1	2
Beta-glucan	1	2
Bifidobacterium Infantis	1	2
Bioflavonoids	1	2
Bitter Orange	1	2
Bixin	1	2
Blackberry	1	2
Broccoli Sprouts	1	2
Carvacrol	1	2
Cashew	1	2
Catuaba	1	2
Celery	1	2
Celery Oil	1	2
Chia	1	2
Chokeberry	1	2
Chrysanthemum Morifolium	1	2
Cinnamon	1	2
Coconut Oil	1	2
Coconut Water	1	2
Common bean	1	2
Cucurbitacin B	1	2
Curry Leaves	1	2
D-Limonene	1	2
Delta-tetrahydrocannabinol (THC)	1	2
Dill	1	2
Diosmetin	1	2
Dong Quai	1	2
Elderberry	1	2
Emodin	1	2
Eriodictyol	1	2
FOS (Fructooligosaccharides)	1	2
Feijoa	1	2
Fermented Foods and Beverages	1	2
Feverfew	1	2
Fisetin	1	2
Fucoidan	1	2
Fucoxanthin	1	2
Garcinia Mangostana	1	2
Garcinia kola	1	2
Geranium	1	2
Gingerol	1	2
Goldenrod	1	2
Guava	1	2
Gynostemma	1	2
Herb Bennet	1	2
Hibiscus	1	2
Indole-3-Carbinol	1	2
Isoflavones	1	2
Isoquercitrin	1	2
Kratom	2	2
Kudzu	1	2
Lactobacillus casei	1	2
Lactobacillus gasseri	1	2
Lactobacillus kefiranofaciens	1	2
Lactobacillus salivarius	1	2
Lemon Verbena	1	2
Lettuce	1	2
Licorice	1	2
Lignan	1	2
Ligustrazine	1	2
Lobelia	1	2
Loquat	1	2
Medicinal Mushrooms	1	2
Mimosa pudica	1	2
Musk (Animal)	1	2
Neem	1	2
Nettle	1	2
Noni	1	2
Nutmeg	1	2
Okra	1	2
Olive leaf extract	1	2
Orange: Mandarin	1	2
P-Coumaric Acid	1	2
Panax Ginseng	1	2
Parsley	1	2
Persimmon	1	2
Phloretin	1	2
Piperlongumine	1	2
Pumpkin	1	2
Punicalagin	1	2
Pycnogenol (Pine Bark)	1	2
Radish	1	2
Red Sage	1	2
Safranal	1	2
Sage	1	2
Salvia miltiorrhiza	1	2
Schisandra	1	2
Scopoletin	1	2
Shikonin	1	2
Shitake Mushroom	1	2
Skullcap: Chinese	2	2
Spinach	1	2
Spirulina	1	2
Stilbenes	1	2
Strawberry	1	2
Tarragon	1	2
Terminalia	1	2
Tetrahydrocurcumin	1	2
Theaflavins	1	2
Thistle	1	2
Tomatidine	1	2
Tomato	1	2
Vanillic Acid	1	2
Verbena officinalis	1	2
Virgin Coconut Oil	1	2
Vitamin E: alpha tocopherol	1	2
Water: Electrolyzed Reduced	1	2
Whey	1	2
White Mulberry	1	2
Woodfordia fruticosa	1	2
Zataria multiflora	1	2
acetyl-11-keto-beta-boswellic acid	1	2
ALA (Alpha-Linolenic Acid)	1	1
Amla Fruit	1	1
Babchi	1	1
Caffeic acid phenethyl ester	1	1
Cannabichromene	1	1
Cannabigerol	1	1
Capsaicin	1	1
Carnosol	1	1
Clove	1	1
Curcumin: Degradiation byproducts	1	1
Endocannabinoids	1	1
Grape	1	1
Graviola	1	1
Kaempferol	1	1
L-Carnitine	1	1
Mangosteen	1	1
Mistletoe	1	1
Nobiletin	1	1
Oak	1	1
Oridonin	1	1
Pantothenic Acid (Vitamin B-5)	1	1
Pistachio nut	1	1
Pomelo	1	1
Rhubarb	1	1
Rosmarinic acid	1	1
Soursop	1	1
Thiamine (B-1)	1	1
Verbascoside	1	1
Xanthones	1	1
rhodiola	1	1

Name	AC	CK
Fluoxetine (trade name Prozac)	25	180
Antidepressants	9	85
Sugar Sweetened Beverages	7	80
Sertraline	6	36
Oral Contraceptives	4	33
Selective Serotonin Reuptake Inhibitors (SSRIs)	3	22
Chemotherapy	1	20
Energy Drinks	2	20
Eszopiclone	1	20
Hypnotic Drugs	1	20
Ramelteon	1	20
Statin Drugs	2	20
Zaleplon	1	20
Zolpidem (trade name Ambien)	1	20
Bisphenol A	5	17
Glyphosate	5	17
Nano Plastic-and Micro-Particles	4	16
Simvastatin	2	11
Analgesic: Non-opioid	1	10
Aspirin	1	10
Clozapine	1	10
Electronic Cigarettes	1	10
Fenofibrates	1	10
Fried Foods	1	10
Gliadin	1	10
Hydrocarbons	1	10
Nicotine	1	10
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	10
Phthalates	1	10
Proton-Pump Inhibitors	1	10
Tobacco: Smoking	1	10
Tricresyl phosphates (TCPs)	1	10
Polystyrene nanoparticles	3	6
Lead	2	4
Pesticides	2	4
Sodium Fluoride	2	4
Dexamethasone	2	3
Oseltamivir (trade name Tamiflu)	1	3
Ozempic	1	3
Paroxetine (trade names Seroxat, Paxil)	1	3
Acrylamide	1	2
Aluminum	1	2
Antibiotics	1	2
Arsenic	1	2
Bisphenol F	1	2
Concanavalin A	1	2
Monosodium Glutamate (MSG)	1	2
Prescription Drugs	1	2
Titanium Dioxide	1	2

Name	AC	CK
Exercise	60	469
Yoga	48	436
Acupuncture	29	289
Qigong	19	236
Tai Chi	19	226
Mindfullness Training	21	185
Meditation	21	177
Electroacupuncture	30	144
Exercise: Aerobic	11	107
Acupressure	9	103
Horticultural Therapy (Gardening)	8	100
Integrative Medicine	7	90
Music	9	85
Hyperbaric Treatment	6	80
Light Therapy	7	71
Shinrin-yoku (taking in the atmosphere of the forest)	7	62
Photobiomodulation	15	54
Aromatherapy Massage	6	51
Emotional Freedom Technique	5	41
Exercise: Cycling	5	41
Exercise: Green	5	41
Massage/Therapeutic Touch	3	40
Pilates	3	40
Sunlight exposure	4	40
Therapeutic Breathing	4	40
Yogic Technique: Sudarshan kriya	6	33
Aromatherapy	4	31
Guided Imagery	4	31
Cryotherapy	3	30
Dancing	2	30
Dietary Modification: Low Carbohydrate/Ketogenic	13	27
Exercise: Running	3	25
Exercise: Resistance Training	3	22
Laughter/Humor	4	22
Art Therapy	3	21
Dietary Modification: Mediterranean Diet	3	21
Acupressure: Auricular	2	20
Cognitive Behavioural Approaches	2	20
Hydrotherapy	2	20
Mind-Body Therapies	1	20
Placebo Effect	2	20
Pulsed EMF field (PEMF)	2	20
Thermal Therapy: Far-Infrared	2	20
Magnet Therapy	3	12
Exercise: HIIT	2	11
Behavioral Treatment	1	10
Color Therapy	1	10
Dietary Modification: Vegetarian	1	10
Homeopathic Treatment	1	10
Hormone Replacement Therapy	1	10
Hypnosis	1	10
Light Therapy: Red Colored	1	10
Mantra	1	10
Positive Mood	1	10
Prevent Pain	1	10
Reiki Therapy	1	10
Sauna Therapy	1	10
Sound Therapy	1	10
Whole-Body Vibration	1	10
Yogic Breathing	1	10
Chiropractic treatment	2	4
Grounding: Contact with the Earth	2	3
Mediterranean diet	1	1
Microbiota Transfer Therapy	1	1
Ultrasound therapy	1	1

Name	AC	CK
Electroconvulsive Therapy	9	91
Western Diet	6	44
Electromagnetic Field Harms	4	23
Mobile Phone Radiation	3	21
Chemotherapy	1	20
Blue Light (400−495 nm)	3	14
Vaccination: All	2	13
Angioplasty	2	12
Electromagnetic Radiation	2	12
Air Travel	1	10
Nocebo Effect	1	10
X-ray Mammography	1	10
Vaccination: HPV (Gardasil)	1	3
Vasectomy	1	3
Prenatal Stress	1	2
Stress	1	2
Wi-Fi Radiation	1	1

[+]

Baicalin modulated β-catenin in the relief of inflammatory factor-induced depression complicated with male infertility.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:2112359. Epub 2022 Apr 7. PMID: 35432561

Article Published Date : Dec 31, 2021

Study Type : Animal Study, Human Study

Additional Links

Substances : Flavonoids

Diseases : Depression, Infertility: Male, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Long-term exposure to ambient air pollution was identified as a risk factor for depression onset.Jan 14, 2022

Click here to read the entire abstract

Pubmed Data : Sci Total Environ. 2022 Jan 15 ;804:149986. Epub 2021 Sep 4. PMID: 34798713

Article Published Date : Jan 14, 2022

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Depression

Additional Keywords : Risk Factors

[+]

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.Jan 01, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(5):e0154195. Epub 2016 May 6. PMID: 27152523

[+]

A single dose psilocybin produced rapid and enduring anxiolytic and anti-depressant effects in patients with cancer-related psychological distress.Nov 30, 2016

Click here to read the entire abstract

Pubmed Data : J Psychopharmacol. 2016 Dec ;30(12):1165-1180. PMID: 27909164

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Cancers: All, Depression

Pharmacological Actions : Antidepressive Agents

[+]

A standardized Withania somniferra root extract with piperine alleviates the symptoms of anxiety and depression.Oct 24, 2023

Click here to read the entire abstract

Pubmed Data : J Integr Complement Med. 2023 Oct 25. Epub 2023 Oct 25. PMID: 37878284

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Int. 2018 12 ;121(Pt 1):721-727. Epub 2018 Oct 12. PMID: 30321847

Article Published Date : Jan 11, 2018

Study Type : Human Study

Additional Links

Diseases : Depression, Mood Disorders

Therapeutic Actions : Exercise, Exercise: Cycling, Exercise: Green

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Acupressure can reduce depression and anxiety among older adults in long-term care institutions.Sep 09, 2020

Click here to read the entire abstract

Pubmed Data : Geriatr Nurs. 2020 Sep 10. Epub 2020 Sep 10. PMID: 32921508

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Acupunct Med. 2015 Apr ;33(2):98-102. Epub 2015 Jan 16. PMID: 25595195

Article Published Date : Mar 31, 2015

Click here to read the entire abstract

Pubmed Data : J Psychiatr Res. 2016 Sep 16 ;84:18-26. Epub 2016 Aug 16. PMID: 27693978

Article Published Date : Sep 15, 2016

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Acupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Acupuncture was associated with a significantly greater improvement in depression, pain, and physical and mental health functioning.Nov 30, 2014

Click here to read the entire abstract

Pubmed Data : Med Care. 2014 Dec ;52(12 Suppl 5):S57-64. PMID: 25397825

Click here to read the entire abstract

Pubmed Data : Psychiatry Res. 2018 Dec 31 ;272:467-473. Epub 2018 Dec 31. PMID: 30611966

Article Published Date : Dec 30, 2018

Study Type : Human Study

Additional Links

Substances : Fish, Fruit: All, Vegetables: All

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Adherence to a Mediterranean diet is associated with lower depressive symptoms among U.S. adults.Jan 10, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Am J Epidemiol. 2024 Aug 27. Epub 2024 Aug 27. PMID: 39191648

Article Published Date : Aug 26, 2024

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Depression

[+]

Amelioration of anxiety, depression, and chemotherapy related toxicity after crocin administration during chemotherapy.Jun 23, 2021

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2021 Jun 24. Epub 2021 Jun 24. PMID: 34164855

Article Published Date : Jun 23, 2021

Study Type : Human Study

Additional Links

Diseases : Anxiety, Breast Cancer, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Chemoprotective Agents

[+]

An 8-week hatha yoga intervention resulted in statistically and clinically significant reductions in depression severity.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2017 ;12(3):e0173869. Epub 2017 Mar 16. PMID: 28301561

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Yoga

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

[+]

Anxiety and depression are characterized by enhanced nitro-oxidative stress, lipid peroxidation, and lowered lipid-associated antioxidant defenses.May 06, 2018

Article Published Date : Nov 30, 2017

Study Type : Human Study

Additional Links

Substances : Lavender: Essential Oil

Diseases : Anxiety, Coronary Artery Disease, Depression

Therapeutic Actions : Aromatherapy Massage

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Aromatherapy massage with lavender, chamomile, and rosemary oils is effective in significantly reducing anxiety and depression.Feb 28, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Ther Massage Bodywork. 2022 Mar ;15(1):37-45. Epub 2022 Mar 2. PMID: 35280245

Pubmed Data : Front Psychol. 2021 ;12:678911. Epub 2021 Aug 17. PMID: 34484035

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Magnet Therapy , Meditation

Pharmacological Actions : Antidepressive Agents

[+]

Auricular acupressure is an effective and safe treatment for alleviating symptoms of depressive and anxiety in patients with COVID-19.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Brief targeted mindfulness interventions can help to reduce symptoms and buffer maladaptive responses to negative mood in acutely depressed patients.Oct 11, 2017

Click here to read the entire abstract

Pubmed Data : Behav Res Ther. 2017 Oct 12 ;99:124-130. Epub 2017 Oct 12. PMID: 29078199

Article Published Date : Oct 11, 2017

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Mindfullness Training

Pharmacological Actions : Antidepressive Agents

[+]

Bright light treatment, both as monotherapy and in combination with fluoxetine, was efficacious and well tolerated in the treatment of adults with nonseasonal Nonseasonal Major Depressive Disorder.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : JAMA Psychiatry. 2016 Jan ;73(1):56-63. PMID: 26580307

Clinical efficacy of this herbal drug was significantly higher than citalopram.Dec 31, 2018

Click here to read the entire abstract

Pubmed Data : Curr Drug Discov Technol. 2019 ;16(2):232-238. PMID: 29468978

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Brain Imaging Behav. 2016 Jun ;10(2):437-44. PMID: 26063438

Article Published Date : May 31, 2016

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhen Jiu. 2014 Oct ;34(10):956-60. PMID: 25543421

Article Published Date : Sep 30, 2014

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Depression

Therapeutic Actions : Acupressure: Auricular, Acupuncture

Additional Keywords : Significant Treatment Outcome , Therapeutic Action Superior to Drug Therapy

[+]

Combining therapeutic acupuncture with structured salutogenic dialogue appears to have greater intermediate-term effects than usual primary care in reducing anxiety and depression.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2014 ;14:210. Epub 2014 Jun 30. PMID: 24980440

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Diseases : Anxiety Disorders, Depression, Depressive Disorder, Psychological Distress

Therapeutic Actions : Acupuncture, Integrative Medicine

[+]

Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.Jan 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Avicenna J Phytomed. 2019 Nov-Dec;9(6):505-516. PMID: 31763210

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Substances : Crocin

Diseases : Anxiety, Burning Mouth Syndrome, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Crocus sativus compares favorably in the treatment of mild to moderate depression. Feb 27, 2005

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Pubmed Data : J Ethnopharmacol. 2005 Feb 28 ;97(2):281-4. Epub 2005 Jan 6. PMID: 15707766

Article Published Date : Feb 27, 2005

Study Type : Human Study

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs, Phytotherapy, Plant Extracts

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.Jul 31, 2015

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Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

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Pubmed Data : Phytother Res. 2015 Jan ;29(1):17-21. Epub 2014 Aug 4. PMID: 25091591

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperidines

Diseases : Anxiety Disorders, Depression, Depressive Disorder

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

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Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8258-65. PMID: 16287635

Article Published Date : Sep 23, 2009

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Dancing

[+]

Decreased sunlight exposure is associated with an increased probability of cognitive impairment among depressed individuals. Aug 01, 2009

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Pubmed Data : Cell Mol Life Sci. 2009 Aug;66(16):2759-71. Epub 2009 Jul 5. PMID: 19638195

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Depression

Therapeutic Actions : Sunlight exposure

[+]

Additional Keywords : Risk Reduction

[+]

Depressive symptoms were positively associated with e-cig use in both cross-sectional and longitudinal analyses with a dose-dependent relationship.Oct 15, 2018

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Pubmed Data : Addict Behav. 2018 Oct 16 ;90:85-91. Epub 2018 Oct 16. PMID: 30368023

Article Published Date : Oct 15, 2018

Study Type : Human Study

Additional Links

Diseases : Depression

Additional Keywords : Increased Risk

Problem Substances : Electronic Cigarettes

[+]

Dietary antioxidants and fiber intake and depressive symptoms in Iranian adolescent girls.Nov 30, 2020

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Pubmed Data : Public Health Nutr. 2020 Dec 1:1-18. Epub 2020 Dec 1. PMID: 33256873

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Pubmed Data : Avicenna J Phytomed. 2022 ;12(6):627-637. PMID: 36583177

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Beet

Diseases : Anxiety, Depression

Therapeutic Actions : Exercise: HIIT

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Effect of laser biostimulation and a low-calorie diet vs. a low-calorie diet alone on insulin resistance, inflammatory biomarkers, and depression among obese postmenopausal women.Apr 30, 2022

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Pubmed Data : BMC Complement Med Ther. 2024 May 24 ;24(1):203. Epub 2024 May 24. PMID: 38790041

Article Published Date : May 23, 2024

Study Type : Human Study

Additional Links

Diseases : Anxiety, Depression

Therapeutic Actions : Yoga

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

[+]

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Pubmed Data : Int J Environ Res Public Health. 2022 Nov 18 ;19(22). Epub 2022 Nov 18. PMID: 36429985

Article Published Date : Nov 17, 2022

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Exercise

Pharmacological Actions : Antidepressive Agents, Neuroprotective Agents

[+]

Effects of psilocybin therapy on personality structure.Oct 31, 2018

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Pubmed Data : Acta Psychiatr Scand. 2018 Nov ;138(5):368-378. Epub 2018 Jun 19. PMID: 29923178

Article Published Date : Oct 31, 2018

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy.Mar 24, 1993

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Pubmed Data : Eur J Neurol. 2020 05 ;27(5):779-786. Epub 2020 Mar 13. PMID: 32067288

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : 5-HTP (5-Hydroxytryptophan)

Diseases : Depression, Parkinson's Disease

Pharmacological Actions : Antidepressive Agents

[+]

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Pubmed Data : Taehan Kanho Hakhoe Chi. 2008 Aug ;38(4):493-502. PMID: 18753801

Article Published Date : Jul 31, 2008

Study Type : Human Study

Additional Links

Substances : Bergamot, Frankincense, Lavender

Diseases : Anxiety Disorders, Depression, Pain

Therapeutic Actions : Aromatherapy Massage

[+]

Exercise programs had positive effects in reducing the severity of depression in heart failure patients.Jul 31, 2019

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Pubmed Data : Clin J Oncol Nurs. 2019 Oct 1 ;23(5):E87-E92. PMID: 31538976

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Pubmed Data : Am J Clin Nutr. 2016 09 ;104(3):704-14. Epub 2016 Jul 13. PMID: 27413131

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Flavonoids

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression.Oct 30, 2023

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Pubmed Data : Neuroimage. 2023 Oct 31 ;283:120438. Epub 2023 Oct 31. PMID: 37918179

Article Published Date : Oct 30, 2023

Study Type : Human Study

Additional Links

Substances : Fruit: All

Diseases : Depression

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

Higher levels of medial prefrontal cortical glutamate were associated with negatively experienced ego dissolution.May 22, 2020

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Pubmed Data : Int J Neuropsychopharmacol. 2005 Jun ;8(2):215-21. Epub 2004 Sep 30. PMID: 15458612

Article Published Date : May 31, 2005

Additional Keywords : Plant Extracts

[+]

Intake of coffee associated with decreased depressive symptoms among elderly Japanese women: a multi-center cross-sectional study.Jun 21, 2019

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Pubmed Data : J Epidemiol. 2019 Jun 22. Epub 2019 Jun 22. PMID: 31231097

Article Published Date : Jun 21, 2019

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Intake of raw fruits and vegetables is associated with better mental health than intake of processed fruits and vegetables.Dec 31, 2017

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Pubmed Data : Front Immunol. 2023 ;14:1158137. Epub 2023 Mar 23. PMID: 37033942

Article Published Date : Dec 31, 2022

Study Type : Human Study

Additional Links

Substances : Lactobacillus plantarum

Diseases : Anxiety, Depression, Insomnia

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Gastrointestinal Agents

[+]

L. reuteri DSM 17938 was associated with a significant reduction in crying time in colicky infants, and showed improvement in maternal depression.Jan 06, 2022

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Pubmed Data : Clin Pract. 2022 Jan 7 ;12(1):37-45. Epub 2022 Jan 7. PMID: 35076544

Article Published Date : Jan 06, 2022

Study Type : Human Study

Additional Links

Substances : Lactobacillus reuteri

Diseases : Colic, Depression

Pharmacological Actions : Gastrointestinal Agents

[+]

[+]

Loneliness: A signature mental health concern in the era of COVID-19.Dec 31, 2019

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Pubmed Data : Psychiatry Res. 2020 08 ;290:113117. Epub 2020 May 23. PMID: 32480121

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Diseases : Depression, Suicidal Ideation

Additional Keywords : Increased Risk, Loneliness, Social Isolation, Stay-at-home orders

[+]

Long distance ski racing is associated with lower long-term incidence of depression in a population based, large-scale study.Aug 30, 2019

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Pubmed Data : Geriatr Nurs. 2025 Jul 8 ;65:103498. Epub 2025 Jul 8. PMID: 40633237

Article Published Date : Jul 07, 2025

Study Type : Human Study

Additional Links

Diseases : Depression, Fatigue, Sleep Disorders

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Antidepressive Agents

[+]

Lower vitamin D levels are associated with depression in patients with gout.Dec 31, 2018

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Pubmed Data : Neuropsychiatr Dis Treat. 2019 ;15:227-231. Epub 2019 Jan 14. PMID: 30679908

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Depression, Gout, Vitamin D Deficiency

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Factors

[+]

LPT is able to promote pain relief and improvement of jaw movements in elderly patients with TMD.Mar 31, 2015

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Pubmed Data : Lasers Med Sci. 2015 Apr ;30(3):953-9. Epub 2013 Dec 24. PMID: 24366293

Click here to read the entire abstract

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Pubmed Data : J Psychiatr Res. 2019 Apr 9 ;114:24-33. Epub 2019 Apr 9. PMID: 31015098

Article Published Date : Apr 08, 2019

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Acupuncture, Electroacupuncture

Pharmacological Actions : Antidepressive Agents

[+]

Meditation based lifestyle modification (MBLM) in outpatients with mild to moderate depression.Dec 31, 2020

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Pubmed Data : Nutrients. 2018 Dec 18 ;10(12). Epub 2018 Dec 18. PMID: 30567286

Article Published Date : Dec 17, 2018

Study Type : Human Study

Additional Links

Substances : Fish, Omega-3 Fatty Acids

Diseases : Depression

Pharmacological Actions : Antidepressive Agents, Prophylactic Agents

Additional Keywords : Risk Reduction

[+]

Moderate physical activity may help alleviating depressive symptoms.Jul 17, 2019

Click here to read the entire abstract

Pubmed Data : Psychiatry Res. 2019 Jul 18 ;280:112489. Epub 2019 Jul 18. PMID: 31442671

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Transl Psychiatry. 2020 May 4 ;10(1):128. Epub 2020 May 4. PMID: 32366824

Pubmed Data : J Affect Disord. 2018 04 1 ;230:84-86. PMID: 29407543

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

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View the Evidence: 568 Abstracts with Depression Research

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Baicalin modulated β-catenin in the relief of inflammatory factor-induced depression complicated with male infertility.Dec 31, 2021

Long-term exposure to ambient air pollution was identified as a risk factor for depression onset.Jan 14, 2022

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.Jan 01, 2009

40 arthritic patients divided into 2 groups, one was treated with an essential oil blend which decreased pain and depression levels.Jan 31, 2005

A 4-week auricular acupressure plan led to improvement in sleep quality, anxiousness, and depressed mood in student nurses. Jan 31, 2018

A 4-week training of aerobic exercise significantly improves functional capacity in patients with major depressive disorder.Dec 31, 2015

A 5-week Seminar on the biopsychosocial-spiritual model of self-care improves anxiety, self-compassion, mindfulness, depression, and stress.May 29, 2019

A combination of probiotics and magnesium orotate attenuate depression.Mar 31, 2017

A combined high-sugar and high-saturated-fat dietary pattern is associated with more depressive symptoms.Aug 31, 2017

A dose of 200 mg of CoQ10 supplement daily for 8 weeks can reduce depression and fatigue.Apr 30, 2024

A higher consumption of dietary fiber was a protective factor for depression and anxiety in hypertensive patients.Nov 19, 2021

A Mediterranean dietary pattern protects against depressive disorders. Oct 01, 2009

A pilot controlled trial of a combination of electroacupuncture and psychological intervention for post-stroke depression.Nov 08, 2022

A pilot horticultural therapy program had beneficial effects on serving veterans with mental health issues.Jul 31, 2018

A pro-inflammatory diet was associated with a significantly higher risk of depression in a Mediterranean population.Sep 06, 2015

A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome.Apr 24, 2024

A single dose psilocybin produced rapid and enduring anxiolytic and anti-depressant effects in patients with cancer-related psychological distress.Nov 30, 2016

A standardized Withania somniferra root extract with piperine alleviates the symptoms of anxiety and depression.Oct 24, 2023

Acetyl-l-carnitine improves depression in senile patients.Jan 01, 1990

Acetyl-l-carnitine may have therapeutic properties in geriatric depression.Dec 01, 2003

Active commuting through natural environments is associated with better mental health.Jan 11, 2018

Acupressure can reduce depression and anxiety among older adults in long-term care institutions.Sep 09, 2020

Acupressure with massage has a beneficial effect on fatigue and depression in patients with end-stage renal disease.Aug 01, 2007

Acupuncture compares favorably to fluoxetine hcl (Prozac) in the treatment of depression, without the adverse side effects. Jul 01, 2009

Acupuncture is a promising intervention for patients with chronic anxiety symptoms that have proven resistant to other forms of treatment.Mar 31, 2015

Acupuncture is effective in improving post-stroke depression in post-stroke depression patients.Aug 01, 2010

Acupuncture is effective to attenuate stress and stimulate lymphocyte proliferation in the elderly.Oct 22, 2010

Acupuncture may achieve treatment effects by modulating the corticostriatal reward and motivation circuitry in MDD patients.Sep 15, 2016

Acupuncture was associated with a significantly greater improvement in depression, pain, and physical and mental health functioning.Nov 30, 2014

Adapted cold shower as a potential treatment for depression.Jan 01, 2008

Add-on treatment with curcumin has antidepressive effects in thai patients with major depression.Dec 31, 2017

Adherence to a healthy dietary pattern is associated with less severe depressive symptoms among adolescent girls.Dec 30, 2018

Adherence to a Mediterranean diet is associated with lower depressive symptoms among U.S. adults.Jan 10, 2022

Adjunctive bright light treatment with gradual advance in unipolar major depressive disorder with evening chronotype.Dec 31, 2021

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers.Nov 17, 2021

Aerobics training can effectively improve the anxiety and depression of perimenopausal women.Dec 31, 2021

AGE accumulation in the skin is independently associated with higher levels of depressive symptoms and depressive disorder.Jun 05, 2016

Aging as a context for the role of inflammation in depressive symptoms.Dec 31, 2019

Alterations in brain structure and amplitude of low-frequency after 8 weeks of mindfulness meditation training in meditation-naïve subjects.Jul 28, 2019

Ambient air pollution and depressed mood in the national longitudinal study of adolescent to adult health.Aug 26, 2024

Amelioration of anxiety, depression, and chemotherapy related toxicity after crocin administration during chemotherapy.Jun 23, 2021

An 8-week hatha yoga intervention resulted in statistically and clinically significant reductions in depression severity.Dec 31, 2016

An intervention of yoga plus coherent breathing led to a decrease in depressive symptoms in patients with major depressive disorder.Nov 30, 2017

An inverse association between the omega-3 index and depressive symptoms was observed among participants with elevated oxidative stress.Mar 01, 2016

Antidepressant effect of shaded white leaf tea.Aug 02, 2020

Anxiety and depression are characterized by enhanced nitro-oxidative stress, lipid peroxidation, and lowered lipid-associated antioxidant defenses.May 06, 2018

Anxiety, depression, perceived executive function and sugar sweetened beverages.Jan 02, 2023

Arginine bioavailability may be decreased in major depressive disorder.Dec 26, 2017

Aromatherapy massage can be an effective and safe intervention to alleviate specific agitated behaviors and depressive mood in individuals with dementia.Aug 31, 2016

Aromatherapy massage can help in alleviating psychological and physiological responses among patients with acute coronary syndrome.Nov 30, 2017

Aromatherapy massage with lavender, chamomile, and rosemary oils is effective in significantly reducing anxiety and depression.Feb 28, 2022

Art therapy as an adjunctive treatment for major depressive disorder in the elderly can improve depressive and anxiety symptoms.Jun 30, 2018

Art therapy improved depression and influenced fatigue levels in cancer patients on chemotherapy.Oct 31, 2007

Association between consumption of fruits and vegetables in midlife and depressive symptoms in late life.May 27, 2024

Association between energy drink consumption, depression and suicide ideation in Korean adolescents.Feb 28, 2020

Association between glyphosate exposure and cognitive function, depression, and neurological diseases.Aug 08, 2023

Association between microplastics exposure and depressive symptoms in college students.Apr 14, 2025

Association between Toxoplasma gondii infection in brain and a history of depression in suicide decedentsOct 12, 2021

Association between vitamin D insufficiency and depressive symptoms, and functional disability.Jun 16, 2024

Association of depressive symptoms with ambient PM 2.5 in middle-aged and elderly Chinese adults.Aug 17, 2021

Associations between exercise, inflammation and symptom severity in those with mental health disorders.Jul 24, 2021

Associations of social isolation with anxiety and depression during the early COVID-19 pandemic.Dec 31, 2019

Audio-guided mindfulness meditation during transcranial magnetic stimulation sessions for the treatment of major depressive disorder.Dec 31, 2020

Auricular acupressure is an effective and safe treatment for alleviating symptoms of depressive and anxiety in patients with COVID-19.Dec 31, 2021

Auricular acupressure using vaccaria seeds was effective in decreasing depression in outpatient nurses.Jul 31, 2021

Ayahuasca has therapeutic potential in depression and that this potential is due to an increase in mindfulness capacities.Feb 29, 2016

Ayahuasca may have fast-acting and sustained anti-depressive properties.Dec 07, 2015

Ayahuasca's antidepressant effects covary with behavioural activation as well as mindfulness.Sep 29, 2019

B vitamins could be used to improve mood symptoms and mental health quality of life in adults with depression.Dec 31, 2012

Baduanjin is an effective intervention for improving physical and psychological health outcomes among breast cancer survivors.Mar 31, 2019

Beneficial effect of adjunct yoga therapy in depressive disorders.Oct 31, 2019

Beneficial effects of celery seed extract on anxiety and depression in hypertensive patients.Jan 31, 2023

Depression

View the Evidence:
568 Abstracts with Depression Research