Dermatitis: Contact

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17 Substances Researched for Dermatitis: Contact
NameACCKFocus
Grape110Locked
Henna110Locked
Polyphenols110Locked
Rosemary110Locked
Vitamin C110Locked
Paeoniflorin46Locked
Palmitoylethanolamide 24Locked
Cannabidiol12Locked
Coconut Oil12Locked
Cordyceps sinensis12Locked
Honeysuckle12Locked
Isoflavones12Locked
Pomegranate12Locked
Pterostilbene12Locked
Xanthones12Locked
Burdock11Locked
Xanthohumol11Locked
12 Problem Substances Researched for Dermatitis: Contact
NameACCKFocus
Iodopropynyl Butylcarbamate 323Locked
Sodium lauryl sulfate 220Locked
Paraphenylenediamine (Hair Dye Ingredient)211Locked
Aluminum110Locked
Glyceryl Monothioglycolate 110Locked
Nickelous Sulfate110Locked
Vaccine Adjuvants110Locked
Sodium hexametaphosphate12Locked
2-bromo-2-nitroethanol 11Locked
Formaldehyde11Locked
Formaldehyde Releasers 11Locked
Tattoo Ink11Locked
1 Problematic Actions Researched for Dermatitis: Contact
NameACCKFocus
Vaccination: All110Locked

View the Evidence:
31 Abstracts with Dermatitis: Contact Research

[+]

19 cases of persistent (lasting for many years) itching nodules after vaccination with aluminum-adsorbed vaccines. Hypersensitivity to aluminum may also occur in infants following DTaP/polio + HiB vaccination. Nov 01, 2005

Pubmed Data : Eur J Pediatr. 2005 Nov ;164(11):691-7. Epub 2005 Jul 26. PMID: 16044278
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Diseases : Dermatitis: Contact
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Early onset irritant skin damage in apprentice hair dressers has been observed. Nov 01, 1995

Pubmed Data : Hautarzt. 1995 Nov;46(11):771-8. PMID: 8641883
Article Published Date : Nov 01, 1995
Study Type : Human Study
Additional Links
Diseases : Dermatitis: Contact, Occupation Related Diseases: Hair Dressers
[+]

Hairdressers with dermatitis should always be patch tested regardless of atopy status due to common allergies to hair dyes and permanent solution.Mar 01, 2010

Pubmed Data : Contact Dermatitis. 2010 Mar;62(3):177-81. PMID: 20565505
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Diseases : Dermatitis: Contact
Additional Keywords : Vocation: Hairdresser
Problem Substances : Glyceryl Monothioglycolate , Nickelous Sulfate, Paraphenylenediamine (Hair Dye Ingredient)
[+]

Iodopropynyl butylcarbamate exhibits irritant properties.Dec 01, 2010

Pubmed Data : Dermatitis. 2010 Dec;21(6):303-10. PMID: 21144341
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Diseases : Dermatitis: Contact, Diaper Rash
Problem Substances : Iodopropynyl Butylcarbamate
Adverse Pharmacological Actions : Irritant
[+]

Iodopropynyl butylcarbamate use in cosmetics may contribute to eczema in some individuals.Sep 01, 2004

Pubmed Data : Br J Dermatol. 2004 Sep;151(3):608-15. PMID: 15377347
Article Published Date : Sep 01, 2004
Study Type : Human Study
Additional Links
Diseases : Dermatitis: Contact, Eczema
Problem Substances : Iodopropynyl Butylcarbamate
Adverse Pharmacological Actions : Irritant
[+]

Marigold and rosemary cream show a protective effect against irritant contact dermatitis.Jul 01, 2005

Pubmed Data : Skin Pharmacol Physiol. 2005 Jul-Aug;18(4):195-200. Epub 2005 May 20. PMID: 15908760
Article Published Date : Jul 01, 2005
Study Type : Human Study
Additional Links
Substances : Rosemary
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
Problem Substances : Sodium lauryl sulfate
[+]

Pre-treatment of skin sites with vitamin C led to a reduction in the intensity, or even ablation, of the cutaneous allergic reaction to p-phenylenediamine.May 31, 2016

Pubmed Data : Contact Dermatitis. 2016 Jun ;74(6):368-72. Epub 2016 Mar 29. PMID: 27027508
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Dermatitis: Contact
Pharmacological Actions : Antioxidants
[+]

Red grape polyphenol oral administration improves immune response in women affected by nickel-mediated allergic contact dermatitis.Jan 12, 2020

Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2020 03 13. Epub 2020 Mar 13. PMID: 32167433
Article Published Date : Jan 12, 2020
Study Type : Human Study
Additional Links
Substances : Grape, Polyphenols
Diseases : Dermatitis: Contact
Pharmacological Actions : Immunomodulatory
[+]

Sodium lauryl sulfate has irritant and dehydrating properties.Sep 01, 1988

Pubmed Data : J Am Acad Dermatol. 1988 Sep;19(3):496-502. PMID: 3049697
Article Published Date : Sep 01, 1988
Study Type : Human Study
Additional Links
Diseases : Dermatitis: Contact, Dry Skin
Problem Substances : Sodium lauryl sulfate
Adverse Pharmacological Actions : Dehydrating, Irritant
[+]

Topical formulation of henna might be a complementary choice for improving contact dermatitis in patients using lower limb prosthetics.Feb 29, 2020

Pubmed Data : Complement Ther Med. 2020 Mar ;49:102316. Epub 2020 Jan 15. PMID: 32147071
Article Published Date : Feb 29, 2020
Study Type : Human Study
Additional Links
Substances : Henna
Diseases : Dermatitis: Contact
[+]

Contact dermatitis due to iodopropynyl butylcarbamate in moist sanitary wipes has been reported.Oct 01, 2003

Pubmed Data : Hautarzt. 2003 Oct;54(10):970-4. PMID: 14513245
Article Published Date : Oct 01, 2003
Study Type : Human: Case Report
Additional Links
Diseases : Dermatitis: Contact
Problem Substances : Iodopropynyl Butylcarbamate
Adverse Pharmacological Actions : Irritant
[+]

Characterization and anti-allergic effect of a polysaccharide from the flower buds of Lonicera japonica.Nov 05, 2012

Pubmed Data : Carbohydr Polym. 2012 Nov 6 ;90(4):1642-7. Epub 2012 Jul 22. PMID: 22944428
Article Published Date : Nov 05, 2012
Study Type : Animal Study
Additional Links
Substances : Honeysuckle
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary coconut oil ameliorates skin contact hypersensitivity through mead acid production in mice.Mar 05, 2019

Pubmed Data : Allergy. 2019 Mar 6. Epub 2019 Mar 6. PMID: 30843234
Article Published Date : Mar 05, 2019
Study Type : Animal Study
Additional Links
Substances : Coconut Oil
Diseases : Dermatitis: Contact, Hypersensitivity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Diets containing pomegranate polyphenol and soy isoflavone attenuate contact hypersensitivity in mice.Feb 28, 2019

Pubmed Data : Biosci Biotechnol Biochem. 2019 Mar ;83(3):525-530. Epub 2018 Nov 10. PMID: 30417760
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Isoflavones, Pomegranate
Diseases : Dermatitis: Contact
[+]

Effect of hot water extract of a glycyrrhizin-deficient strain of Glycyrrhiza uralensis on contact hypersensitivity.Feb 29, 2020

Pubmed Data : J Nat Med. 2020 Mar ;74(2):415-420. Epub 2020 Jan 8. PMID: 31916003
Article Published Date : Feb 29, 2020
Study Type : Animal Study
Additional Links
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Allergic Agents
[+]

Effects of fisetin on allergic contact dermatitis via regulating the balance of Th17/Treg.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Comput Math Methods Med. 2022 ;2022:9222541. Epub 2022 Apr 9. PMID: 35437448
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Dermatitis: Contact
Pharmacological Actions : Immunomodulatory
[+]

Paeoniflorin attenuates the allergic contact dermatitis response.May 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Immunopharmacol. 2021 May 6 ;96:107687. Epub 2021 May 6. PMID: 33965879
Article Published Date : May 05, 2021
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents, Immunosuppressive Agents
[+]

Paeoniflorin inhibits inflammatory responses in mice with allergic contact dermatitis.Nov 30, 2013

Pubmed Data : Inflamm Res. 2013 Dec ;62(12):1035-44. Epub 2013 Oct 5. PMID: 24096935
Article Published Date : Nov 30, 2013
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-2 Downregulation, Interleukin-4 upregulation
[+]

Palmitoylethanolamide reduces inflammation and itch in a mouse model of contact allergic dermatitis.Nov 14, 2016

Pubmed Data : Eur J Pharmacol. 2016 Nov 15 ;791:669-674. Epub 2016 Oct 5. PMID: 27720681
Article Published Date : Nov 14, 2016
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Dermatitis: Contact, Inflammation
Pharmacological Actions : Angiogenesis Inhibitors
[+]

Pediococcus pentosaceus-fermented Cordyceps militaris inhibits inflammatory reactions and alleviates contact dermatitis.Nov 06, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Nov 7 ;19(11). Epub 2018 Nov 7. PMID: 30405049
Article Published Date : Nov 06, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps sinensis
Diseases : Dermatitis: Contact, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective role of palmitoylethanolamide in contact allergic dermatitis.May 31, 2010

Pubmed Data : Allergy. 2010 Jun 1 ;65(6):698-711. Epub 2009 Nov 11. PMID: 19909294
Article Published Date : May 31, 2010
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Dermatitis: Contact, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Pterostilbene attenuates hexavalent chromium-induced allergic contact dermatitis.Nov 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2018 Nov 27 ;7(12). Epub 2018 Nov 27. PMID: 30486377
Article Published Date : Nov 26, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sodium hexametaphosphate is a skin irritant topically and has adverse kidney effects when ingested (10% diet) animal experiments..Jan 01, 2001

Pubmed Data : Int J Toxicol. 2001;20 Suppl 3:75-89. PMID: 11766135
Article Published Date : Jan 01, 2001
Study Type : Animal Study
Additional Links
Diseases : Dermatitis: Contact, Kidney Damage
Problem Substances : Sodium hexametaphosphate
Adverse Pharmacological Actions : Nephrotoxic
[+]

This is the first demonstration of the anti-inflammatory properties of CBD in an experimental model of allergic contact dermatitis.Apr 08, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Exp Ther. 2018 Apr 9. Epub 2018 Apr 9. PMID: 29632236
Article Published Date : Apr 08, 2018
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Xanthone suppresses allergic contact dermatitis in vitro and in vivo.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Immunopharmacol. 2020 Jan ;78:106061. Epub 2019 Dec 9. PMID: 31821937
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Xanthones
Diseases : Dermatitis: Contact
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Paeoniflorin inhibits MRGPRX2-mediated pseudo-allergic reaction via calcium signaling pathway.Jan 31, 2020

Pubmed Data : Phytother Res. 2020 Feb ;34(2):401-408. Epub 2019 Oct 31. PMID: 31667930
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Allergies, Atopic Dermatitis, Dermatitis: Contact
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Dose Response
[+]

Burdock extracts might be useful as a therapeutic agent for treating various forms of allergic inflammation.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Mol Allergy. 2011 ;9(1):4. Epub 2011 Feb 8. PMID: 21303540
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Burdock
Diseases : Allergies, Dermatitis: Contact, Inflammation
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, Interleukin-4 downregulation, Interleukin-5 downregulation, NF-kappaB Inhibitor
[+]

Formaldehyde releasers (and not simply the formaldehyde released) commonly used as cosmetic preservatives may cause contact allergies.Oct 01, 2010

Pubmed Data : Contact Dermatitis. 2010 Oct;63(4):192-202. Epub 2010 Aug 20. PMID: 20731691
Article Published Date : Oct 01, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Dermatitis: Contact
Problem Substances : 2-bromo-2-nitroethanol , Formaldehyde, Formaldehyde Releasers
Adverse Pharmacological Actions : Irritant
[+]

Paeoniflorin inhibits the maturation and immunostimulatory function of allergen-induced murine dendritic cells.Mar 31, 2014

Pubmed Data : Int Immunopharmacol. 2014 Apr ;19(2):221-32. Epub 2014 Feb 15. PMID: 24534772
Article Published Date : Mar 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Allergies, Dermatitis: Contact
Pharmacological Actions : Immunomodulatory
[+]

Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos as been reported.Mar 01, 2010

Pubmed Data : Indian J Dermatol Venereol Leprol. 2010 Mar-Apr;76(2):165-7. PMID: 20228546
Article Published Date : Mar 01, 2010
Study Type : Commentary
Additional Links
Diseases : Dermatitis: Contact, Keloid
Problem Substances : Paraphenylenediamine (Hair Dye Ingredient), Tattoo Ink
[+]

Xanthohumol inhibits IL-12 production and reduces chronic allergic contact dermatitis.Apr 30, 2010

Pubmed Data : Int Immunopharmacol. 2010 May ;10(5):556-61. Epub 2010 Feb 6. PMID: 20144742
Article Published Date : Apr 30, 2010
Study Type : In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Dermatitis: Contact, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, NF-kappaB Inhibitor

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