Diabetic Complications

Name	AC	CK
Curcumin	47	110
Vitamin D	12	78
Astragaloside	22	76
Berberine	20	48
Ginger	16	46
Alpha-Lipoic Acid	11	45
Omega-3 Fatty Acids	6	45
Resveratrol	26	45
Cinnamon	8	44
Flavonoids	18	44
Nigella sativa (aka Black Seed)	13	42
Astaxanthin	22	40
Carnitine	4	40
Magnesium	4	40
Vitamin C	9	40
Ginsenosides	19	36
Bee Propolis	8	32
Quercetin	13	32
Okra	7	31
Sesame Seed Oil	2	30
Vitamin B-12	3	30
Panax Notoginseng	4	25
Polyphenols	10	25
Probiotics	4	23
Puerarin	12	23
Cocoa	4	22
B-complex	2	20
Benfotiamine	2	20
Coenzyme Q10	7	20
Fish	1	20
Grape Seed Extract	10	20
Hibiscus	2	20
Soy Protein	2	20
Thiamine (B-1)	2	20
EGCG (Epigallocatechin gallate)	12	19
Genistein	11	18
Gingerol	8	18
Moringa oleifera	9	17
Paeoniflorin	10	17
Thymoquinone	10	17
Dates	4	16
Cannabidiol	9	15
Citrus naringin	7	15
Fenugreek	8	14
Fucoidan	8	14
Garlic	6	14
Mangiferin	8	14
Naringenin	8	14
Peony	4	14
Pomegranate	8	14
Cannabis	3	13
Cinnamaldehyde	6	13
Goji	7	13
Melatonin	7	13
Nettle	7	13
Rose	6	13
Almond	2	12
Crocin	6	12
Delta-tetrahydrocannabinol (THC)	2	12
Diosgenin	7	12
Flaxseed	2	12
Ginkgo biloba	6	12
Green Tea	2	12
Honey	2	12
Lotus	5	12
Luteolin	5	12
Pycnogenol (Pine Bark)	2	12
Saffron	2	12
Tanshinone IIA	7	12
Taurine	2	12
Anthocyanins	7	11
Ellagic Acid	6	11
NAC (N-acetyl-L-cysteine)	6	11
Rutin	5	11
Selenium	2	11
Vitamin E	5	11
Arginine	1	10
Ascorbyl Palmitate	1	10
Bay leaf	1	10
Bifidobacterium Bifidum	1	10
Biotin	1	10
Carnitine, Acetyl-L-	1	10
Chia	1	10
Chromium	1	10
Cranberry	1	10
Curcuminoids	1	10
Eicosapentaenoic acid (EPA)	1	10
Fisetin	4	10
Garlic: Aged	1	10
Homeopathic Medicine: All	1	10
Kanuka Honey	1	10
Kiwifruit	1	10
Lactobacillus Acidophilus	1	10
Lactobacillus casei	1	10
Leucine	1	10
Oyster Mushroom	1	10
Red Yeast Rice	1	10
Rice Bran	1	10
Roselle	1	10
Sesame Seeds	1	10
St. Johns Wort	5	10
Terminalia chebula	1	10
Turmeric	1	10
Ubiquinol	1	10
Vitamin B-6	1	10
Yoghurt	1	10
Sulforaphane	5	9
Asiatic Acid	4	8
Banana	4	8
Gastrodin	3	8
Hibiscus sabdariffa	4	8
Paeonol	4	8
Prunella vulgaris	3	8
Pterostilbene	5	8
Purslane	4	8
Sesamin	4	8
Strawberry	4	8
Thymol	3	8
Ursolic Acid	4	8
Dogwood	4	7
Fish Oil	4	7
Gallic Acid	4	7
Hesperidin	4	7
Lycopene	4	7
Myricetin	4	7
Royal Jelly	4	7
Zinc	4	7
Allicin	3	6
Bael	3	6
Betulinic acid	4	6
Caffeic Acid	3	6
Caffeic acid phenethyl ester	3	6
Chaga Mushroom (Inonotus obliquus)	3	6
Chrysin	4	6
Fig	2	6
Formononetin	3	6
Gamma-Linoleic Acid (GLA)	2	6
Ginseng (Korean)	3	6
Gotu Kola	3	6
Hawthorn	3	6
Lychee	3	6
Mugwort	3	6
Nobiletin	4	6
Oligonol	3	6
P-Coumaric Acid	3	6
Phloretin	3	6
Piperine	2	6
Rhubarb	2	6
Rosemaric Acid	3	6
Salvia miltiorrhiza	4	6
Sesamol	3	6
Walnut	3	6
6-Shogaol	3	5
Arctigenin	3	5
Bamboo	3	5
Carvacrol	3	5
Cordyceps sinensis	3	5
Lupeol	3	5
Mangosteen	3	5
Mulberry	3	5
Onion	3	5
Parthenolide	3	5
Rooibos	3	5
Acetyl-l-carnitine	1	4
Amla Fruit	2	4
Apigenin	3	4
Butyrate	2	4
Cannabinoids	3	4
Carnosic Acid	2	4
Carnosine	1	4
Chamomile	2	4
Corn: Purple	2	4
Dill	2	4
Diosmin	2	4
Embelia ribes	1	4
False Black Pepper	2	4
Geraniol	2	4
Histidine	1	4
Kaempferol	2	4
Medicinal Mushrooms	2	4
Peanut	2	4
Pomegranate Seed	2	4
Punicalagin	2	4
Safranal	2	4
Silibinin	2	4
Spirulina	2	4
Stevia	2	4
Tangeretin	3	4
Toona sinensis	2	4
Water: Deep Sea	2	4
Xanthohumol	3	4
Zerumbone	2	4
Bitter Apple	2	3
Bitter Melon	2	3
Broccoli Sprouts	2	3
Burdock	2	3
Fucoxanthin	2	3
Hibiscus rosa-sinensis	2	3
Liquiritigenin	2	3
Lutein	2	3
Oak	2	3
Piceatannol	2	3
Safflower	2	3
Silver (nanoparticles)	2	3
Urolithin A	2	3
Acai	1	2
Aduki bean	1	2
Aloe Vera	1	2
Andrographis	1	2
Anise	1	2
Artemisinin	1	2
Artichoke	1	2
Arugula	1	2
Babchi	1	2
Bacopa	1	2
Banana Peel	1	2
Basil	1	2
Basil: Sweet	1	2
Beans: All	1	2
Bee Venom	1	2
Bergamot orange	1	2
Betanin	1	2
Bilberry	1	2
Black Raspberry Seed	1	2
Blueberry	1	2
Boron	1	2
Brazil nut	1	2
Bromelain	1	2
Caraway	1	2
Carnosol	1	2
Celastrol	1	2
Chlorella (Algae)	1	2
Chokeberry	1	2
Citric Acid	1	2
Citrus Peel	1	2
Clove	1	2
Coconut Oil	1	2
Coconut Water	1	2
Coffee	1	2
Cordyceps Militaris	1	2
Coriandrum sativum	1	2
Cumin	1	2
Curcumol	1	2
Cyanidin 3-glucoside	1	2
D-Limonene	1	2
Date Seeds	1	2
Diosmetin	1	2
Echinacea	1	2
Elderberry	1	2
Emodin	1	2
Eucalyptus	1	2
Eugenol	1	2
Ferulic acid	1	2
Folic Acid	1	2
Frankincense	1	2
Ginseng (American)	1	2
Gold (nanoparticles)	1	2
Green Coffee Bean	1	2
Guduchi	1	2
Holy Basil	1	2
Honeysuckle	1	2
Horse Chestnut	1	2
Horsetail	1	2
Huperzine	1	2
Hydrangea	1	2
Hydroxytyrosol	1	2
Inositol	1	2
Lemon	1	2
Ligustrazine	1	2
Lime	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Maitake Mushroom	1	2
Mango leaf	1	2
Manuka Honey	1	2
Maple Syrup	1	2
Marijuana	1	2
Milk Thistle	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Muskmelon	1	2
Myrtle	1	2
Oleanolic acid	1	2
Oleuropein	1	2
Orange	1	2
Oregano	1	2
Orthosiphon	1	2
Palash	1	2
Passion Flower	1	2
Perilla	1	2
Persimmon	1	2
Pine Bark Extract	1	2
Pineapple	1	2
Pistachio nut	1	2
Potato	1	2
Prickly Pear Cactus	1	2
Psychedelics:All	1	2
Pterocarpus marsupium	1	2
Pumpkin	1	2
Rehmannia	1	2
Rice	1	2
Rose Hips	1	2
Rosemary	1	2
Spikenard	1	2
Stilbenes	1	2
Syrian rue	1	2
Taro	1	2
Tarragon	1	2
Tetrahydrocurcumin	1	2
Trigonelline	1	2
Vanillin	1	2
Vinegar	1	2
Vitamin A	1	2
Vitamin E: alpha tocopherol	1	2
Vitamin K	1	2
Vitamin K2	1	2
Vitexins	1	2
Wheat Grass	1	2
Whey	1	2
White Mulberry	1	2
White Tea	1	2
Wogonin	2	2
Xanthones	1	2
Agaricus brasiliensis	1	1
Apple Polyphenols	1	1
Artesunate	1	1
Baicalein	1	1
Berries: All	1	1
Beta-Caryophyllene	1	1
Caffeine	1	1
Cannabigerol	1	1
Catechin	1	1
Chickpea	1	1
Coriolus versicolor	1	1
Corn Silk	1	1
Crocetin	1	1
Cucumber	1	1
Delphinidin	1	1
Eriodictyol	1	1
Fermented Foods and Beverages	1	1
Fruit: All	1	1
Grape	1	1
Graviola	1	1
Isoliquiritigenin	1	1
Isothiocyanates	1	1
Nutmeg	1	1
Oridonin	1	1
Plantago	1	1
Red Sage	1	1
Reishi Mushroom	1	1
Silymarin	1	1
Soy Sauce	1	1
Theophylline	1	1
Zeaxanthin	1	1
neohesperidin	1	1
Vanadium	1	0

Name	AC	CK
Glipizide	2	40
Sulfonylureas	3	40
Rosiglitazone (trade name Avandia)	3	31
Aspirin	2	30
Glibenclamide	2	30
Statin Drugs	3	23
Glyburide	1	20
Organochlorine pesticides	1	20
Persistent organic pollutants (POPs)	1	20
Pesticides	1	20
Fructose	3	14
Insulin	2	12
Bisphenol A	1	10
Metformin	1	10
Simvastatin	1	10
Alloxan	2	4
Atorvastatin	1	3
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	2	3
Pravastatin	1	3
Cadmium	1	2
Sucrose	1	2
Wheat	1	2

Name	AC	CK
Acupuncture	6	60
Yoga	4	41
Exercise	10	32
Laser Treatment: Low-Level	7	28
Hyperbaric Treatment	4	24
Dietary Modification: Vegetarian	1	20
Integrative Medicine	2	20
Therapeutic Breathing	2	20
Transcutaneous electrical nerve stimulation (TENS)	1	20
Exercise: Resistance Training	3	14
Acupressure	1	10
Aromatherapy	1	10
Deep Breathing	1	10
Dietary Modification: Low Carbohydrate	1	10
Dietary Modification: Low Carbohydrate/Ketogenic	1	10
Dietary Modification: Low Glycemic Diet	1	10
Dietary Modification: Mediterranean Diet	1	10
Dietary Modification: Paleolithic/Stone Age Diet	1	10
Fasting/Caloric Restriction	1	10
Hydrotherapy	1	10
Laughter/Humor	1	10
Reflexology	1	10
Thermal Therapy: Far-Infrared	1	10
Whole-Body Vibration	1	10
Electroacupuncture	4	8
Exercise: Aerobic	2	4
Exercise: Endurance	1	2
Exercise: Running	1	2
Light-Emitting Diodes (LEDs) Therapy	1	2
Ozone Therapy	1	1

Name	AC	CK	Focus
Western Diet	1	2

Pharmacological Actions : Renoprotective

[+]

Antioxidant and anti-inflammatory properties of hydroxyl safflower yellow a in diabetic nephropathy.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Kidney Int. 2005 Sep;68(3):1244-9. PMID: 19632552

Article Published Date : Sep 01, 2005

Study Type : Meta Analysis

Additional Links

Diseases : Diabetes: Glycation/A1C, Diabetes Mellitus: Type 2, Hyperglycemia, Insulin Resistance

[+]

These findings suggest that astragaloside IV is a multifaceted renoprotective candidate drug for diabetic nephropathy.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:988. Epub 2020 Jun 30. PMID: 32695006

Article Published Date : Dec 31, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Astragaloside

Diseases : Diabetic Nephropathy

Pharmacological Actions : Renoprotective

[+]

Vegetarian dietary patterns improve cardiometabolic risk factors in diabetes.Jun 12, 2018

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Pubmed Data : Clin Nutr. 2018 Jun 13. Epub 2018 Jun 13. PMID: 29960809

Pubmed Data : Clin Nutr. 2011 Jun ;30(3):351-8. Epub 2010 Dec 16. PMID: 21163558

Pubmed Data : Nutr Metab (Lond). 2009;6:21. Epub 2009 May 6. PMID: 19419563

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Diabetes: Glycation/A1C, Diabetes Mellitus: Type 2

[+]

A pilot study indicated that applying kiwifruit on neuropathic diabetic foot ulcers led to a significant reduction in the size of the foot ulcers and faster wound healing.May 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Res Med Sci. 2014 Jun ;19(6):520-4. PMID: 25197293

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Pubmed Data : J Altern Complement Med. 2009 Sep;15(9):1027-32. PMID: 19757980

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Diseases : Diabetic Neuropathies

Therapeutic Actions : Acupressure

[+]

Acupuncture could bring benefit as an additional treatment for people with diabetic painful neuropathy.May 31, 2014

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Pubmed Data : Acupunct Med. 2014 Jun ;32(3):242-9. Epub 2014 Mar 21. PMID: 24657491

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1468-1471. Epub 2019 Dec 27. PMID: 32010324

Pubmed Data : J Pediatr Endocrinol Metab. 2015 Aug 15. Epub 2015 Aug 15. PMID: 26352081

Article Published Date : Aug 14, 2015

Study Type : Human Study

Additional Links

Diseases : Diabetic Complications

Therapeutic Actions : Aromatherapy

Pharmacological Actions : Antinoceceptive

Additional Keywords : Essential Oils

[+]

Ascorbic acid with metformin is more effective against reducing risks for diabetes related long-term complications.Aug 13, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Clin Biochem Nutr. 2009 Jan;44(1):52-6. Epub 2008 Dec 27. PMID: 19177188

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : Bay leaf

Diseases : Cholesterol: LDL/HDL ratio, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2, Triglycerides: Elevated

Pharmacological Actions : Hypoglycemic Agents

[+]

Benfotiamine inhibits oxidative stress with type 2 diabetes.Sep 01, 2006

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Pubmed Data : Diabetes Care. 2006 Sep;29(9):2064-71. PMID: 16936154

Pubmed Data : Indian J Physiol Pharmacol. 2010 Oct-Dec;54(4):344-54. PMID: 21675032

Article Published Date : Oct 01, 2010

Click here to read the entire abstract

Pubmed Data : Diabetes Care. 2007 Nov;30(11):2804-10. Epub 2007 Aug 8. PMID: 17686832

Article Published Date : Nov 01, 2007

Study Type : Human Study

Additional Links

Substances : Chia

Diseases : Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2

[+]

Cocoa flavanols intake benefits cognitive function in type 1 diabetes.Jun 24, 2019

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Pubmed Data : Psychopharmacology (Berl). 2019 Jun 25. Epub 2019 Jun 25. PMID: 31236643

Effect of Oral carnosine supplementation on urinary TGF-β in diabetic nephropathy.Jun 25, 2021

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Pubmed Data : BMC Nephrol. 2021 Jun 26 ;22(1):236. Epub 2021 Jun 26. PMID: 34174842

Article Published Date : Jun 25, 2021

Study Type : Human Study

Additional Links

Substances : Carnosine

Diseases : Diabetic Nephropathy

Pharmacological Actions : Renoprotective, Transforming growth factor beta (TGF-β) inhibitor

[+]

Effects of resistance training using elastic bands on muscle strength with or without a leucine supplement in elderly patients with type 2 diabetes.Oct 16, 2020

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Pubmed Data : Endocr J. 2020 Oct 17. Epub 2020 Oct 17. PMID: 33071273

Article Published Date : Oct 16, 2020

Study Type : Human Study

Additional Links

Substances : Leucine

Diseases : Diabetes: Cognitive Dysfunction, Diabetes Mellitus: Type 2

Therapeutic Actions : Exercise: Resistance Training

Pharmacological Actions : Neuroprotective Agents

[+]

Inhaled cannabis demonstrated a dose dependent reduction in diabetic peripheral neuropathy pain in patients with treatment refractory pain.Jun 30, 2015

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Pubmed Data : J Pain. 2015 Jul ;16(7):616-27. Epub 2015 Apr 3. PMID: 25843054

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Substances : Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Diabetic Neuropathies

Pharmacological Actions : Analgesics

Additional Keywords : Dose Response, Significant Treatment Outcome

[+]

Kanuka honey was associated with a reduction in weight and improvements in lipid parameters and reduced systolic blood pressure in individuals with type 2 diabetes.May 18, 2015

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Pubmed Data : Eur J Nutr. 2015 May 19. Epub 2015 May 19. PMID: 25986159

[+]

Paradoxically, elevated HbA1c levels were associated with improved survival in patients with diabetes and advanced heart failure.Jan 01, 2006

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Pubmed Data : Am Heart J. 2006 Jan;151(1):91. PMID: 16368297

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Diseases : Diabetes: Cardiovascular Illness, Diabetes: Glycation/A1C

Additional Keywords : Paradoxical Results

[+]

Patients with type 2 diabetes and high levels of serum BPA exhibited about a sevenfold increased risk of developing CKD compared to patients with low levels of serum BPA.Aug 31, 2015

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Pubmed Data : Acta Diabetol. 2015 Sep 1. Epub 2015 Sep 1. PMID: 26321107

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Pubmed Data : J Diabetes Metab Disord. 2021 Jun ;20(1):673-682. Epub 2021 Apr 21. PMID: 34222085

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Med Food. 2006 Fall;9(3):408-12. PMID: 17004907

Article Published Date : Sep 01, 2006

Study Type : Human Study

Additional Links

Substances : Sesame Seed Oil

Diseases : Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2

[+]

The use of glyburide and/or metformin results in increased mortality in type 2 diabetics with coronary artery disease. Feb 01, 2001

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Pubmed Data : Clin Cardiol. 2001 Feb;24(2):151-8. PMID: 11460818

[+]

Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine, a predictor of cardiovascular events, in patients with type 2 diabetes mellitus.Jan 01, 2010

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Pubmed Data : Transl Res. 2010 Jan;155(1):6-9. PMID: 20004356

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Substances : Alpha-Lipoic Acid

Diseases : Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2

[+]

Type 2 diabetic patients patients treated with statin drugs have decreased coq10 levels and may be associated with subclinical diabetic cardiomyopathy reversible by CoQ10 supplementation.Apr 01, 1999

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Pubmed Data : Arzneimittelforschung. 1999 Apr;49(4):324-9. PMID: 10337451

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Pubmed Data : Diabetes Metab Res Rev. 2016 May 7. Epub 2016 May 7. PMID: 27155442

Article Published Date : May 06, 2016

Study Type : Human Study

Additional Links

Diseases : Diabetes Mellitus: Type 2, Diabetic Neuropathies, Vitamin D Deficiency

Additional Keywords : Increased Risk

[+]

Vitamin D deficiency is an independent risk factor for peripheral neuropathy.Dec 31, 2020

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Pubmed Data : F1000Res. 2021 ;10:817. Epub 2021 Aug 16. PMID: 35222988

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Pubmed Data : Endocr J. 2005 Jun ;52(3):369-72. PMID: 16006732

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Pubmed Data : J Ethnopharmacol. 2023 Nov 15 ;316:116667. Epub 2023 May 29. PMID: 37257702

Article Published Date : Nov 14, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Diabetic Nephropathy, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Renoprotective

[+]

These observations showed that pomegranate flower polyphenol ameliorates vasodilation in hyperglycemic rats.Dec 31, 2021

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Pubmed Data : Ultrastruct Pathol. 2021 Nov 2 ;45(6):391-406. Epub 2021 Oct 31. PMID: 34720017

Article Published Date : Nov 01, 2021

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Pubmed Data : Phytother Res. 2010 Jul ;24(7):969-74. PMID: 19957251

Article Published Date : Jun 30, 2010

Study Type : Animal Study

Additional Links

Diseases : Cardiomyopathy, Diabetes: Cardiovascular Illness

Pharmacological Actions : Cardioprotective

[+]

[+]

6-Gingerol attenuates renal damage in streptozotocin-induced diabetes.Feb 27, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Can J Physiol Pharmacol. 2016 Sep 2:1-9. Epub 2016 Sep 2. PMID: 27875075

Article Published Date : Sep 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Avicenna J Phytomed. 2015 Jul-Aug;5(4):333-40. PMID: 26445713

Article Published Date : Jun 30, 2015

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Brain: Oxidative Stress, Diabetic Complications

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

A maple syrup extract alleviates liver injury in type 2 diabetic model mice.Oct 23, 2019

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Pubmed Data : Environ Toxicol. 2016 Jul ;31(7):769-81. Epub 2015 Mar 2. PMID: 25727812

Article Published Date : Jun 30, 2016

Study Type : Animal Study

Additional Links

Substances : Water: Deep Sea

Diseases : Diabetic Complications, Heart Failure

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

Additional Keywords : Anti-Apoptotic, Cardioprotective, Diabetic Complications, Heart Failure, Water: Deep Sea

[+]

Administration of galangin reduced hyperlipidaemia related to the risk of diabetic complications.Nov 30, 2018

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Pubmed Data : Life Sci. 2019 Feb 13. Epub 2019 Feb 13. PMID: 30771313

Article Published Date : Feb 12, 2019

Study Type : Animal Study

Additional Links

Substances : Bael

Diseases : Alzheimer's Disease, Diabetes: Cognitive Dysfunction, Diabetes: Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2018 Oct 11 ;19(10). Epub 2018 Oct 11. PMID: 30314265

Article Published Date : Oct 10, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Allicin, Garlic

Diseases : Diabetic Nephropathy

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Allicin has the potential to help in the treatment of diabetic nephropathy.Nov 14, 2020

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Amelioration of intracerebroventricular streptozotocin-induced cognitive dysfunction by Ocimum sanctum.Sep 30, 2022

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Pubmed Data : Metab Brain Dis. 2022 Oct ;37(7):2533-2543. Epub 2022 Jul 28. PMID: 35900690

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Pubmed Data : Biomed Pharmacother. 2021 Mar ;135:111230. Epub 2021 Feb 1. PMID: 33434853

Article Published Date : Feb 28, 2021

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Pubmed Data : Niger J Physiol Sci. 2011 Nov 23 ;26(1):83-8. Epub 2011 Nov 23. PMID: 22314993

Article Published Date : Nov 22, 2011

Study Type : Animal Study

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Substances : Banana

Diseases : Diabetic Complications

Pharmacological Actions : Calcium Channel Blockers

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

An extract of Prunella vulgaris could be a potential therapeutic agent to ameliorate type 1 diabetes and related complications.Nov 30, 2016

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Pubmed Data : Biomed Pharmacother. 2016 Dec ;84:1008-1018. Epub 2016 Oct 18. PMID: 27768926

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Pubmed Data : PLoS One. 2022 ;17(10):e0276984. Epub 2022 Oct 27. PMID: 36301972

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Soursop

Diseases : Diabetic Complications

Pharmacological Actions : Alpha-glucosidase inhibitor , Anti-Apoptotic, Bcl-2 protein down-regulation, Hypoglycemic Agents

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Anthocyanins may exhibit protective effects against high glucose induced renal injury in diabetic nephropathy via antioxidant activity.Feb 28, 2018

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Pubmed Data : Int J Mol Med. 2018 Mar ;41(3):1608-1618. Epub 2018 Jan 10. PMID: 29328429

Antioxidative stress and anti-inflammatory activity of fucoidan nanoparticles against nephropathy of streptozotocin-induced diabetes.Dec 31, 2021

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Pubmed Data : Saudi J Biol Sci. 2022 Apr ;29(4):2738-2748. Epub 2022 Jan 3. PMID: 35531250

Article Published Date : Mar 31, 2022

Study Type : Animal Study

Additional Links

Substances : Dates

Diseases : Diabetes: Cognitive Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Aqueous extracts of purslane had significant anxiolytic effects and could improve spatial cognitive performance.Dec 31, 2015

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Pubmed Data : J Pharmacopuncture. 2019 Jun ;22(2):109-114. Epub 2019 Jun 30. PMID: 31338251

Article Published Date : May 31, 2019

Study Type : Animal Study

Additional Links

Substances : Mugwort

Diseases : Diabetic Complications, Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

[+]

Artemisia turanica extract has therapeutic effects on renal oxidative damage and lipid profile in diabetes.Aug 31, 2020

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Astaxanthin had an anti-depressant effect on diabetic mice.Dec 21, 2016

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Pubmed Data : Brain Res. 2016 Dec 22. Epub 2016 Dec 22. PMID: 28017669

Article Published Date : Dec 21, 2016

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Brain Inflammation , Depression, Diabetic Complications

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Prophylactic Agents

[+]

Astaxanthin has an inhibitory effect on oxidative stress in diabetic rats. Jul 01, 2008

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Pubmed Data : Int J Vitam Nutr Res. 2008 Jul-Sep;78(4-5):175-82. PMID: 19326340

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Pubmed Data : J Food Sci. 2012 Feb 6. Epub 2012 Feb 6. PMID: 22309505

Article Published Date : Feb 06, 2012

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Diabetes: Cardiovascular Illness, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective

[+]

Astaxanthin may reduce type 2 diabetic associated cognitive declinein rats.Dec 31, 2015

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Pubmed Data : Mol Med Rep. 2016 Jan ;13(1):973-9. Epub 2015 Nov 25. PMID: 26648531

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The Following are Sub-Topics of Diabetic Complications

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View the Evidence: 1424 Abstracts with Diabetic Complications Research

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Ginsenoside can protect against the renal failure in diabetes.Oct 28, 2022

Neuroprotective effect and possible mechanisms of berberine in diabetes-related cognitive impairment.Dec 31, 2021

Protective effect of berberine in diabetic nephropathy.Oct 02, 2022

There is a trend toward an increased overall mortality risk with glyburide versus glimepiride and glipizide versus glimepiride (1.39 [0.99-1.96]) in those with documented coronary artery disease.Jun 01, 2010

A systematic review and meta-analysis of Abelmoschus manihot for diabetic nephropathy.Dec 31, 2018

Antioxidant and anti-inflammatory properties of hydroxyl safflower yellow a in diabetic nephropathy.Dec 31, 2021

Antioxidant and anti-inflammatory properties of resveratrol in diabetic nephropathy.Dec 31, 2021

Aspirin does not prevent cardiovascular events in diabetes mellitus.Jun 01, 2010

Astragaloside IV exerts renal protective effects in animals with diabetes mellitus through multiple signalling pathways.Sep 14, 2020

Fish and long-chain omega-3 fatty acid intake reduce the risk of coronary heart disease and total mortality in diabetic women.Apr 15, 2003

Initiating treatment of type 2 diabetes with glibenclamide or glipizide is associated with increased risk of coronary artery disease in comparison to gliclazide or glimepiride.Dec 01, 2008

Panax notoginseng preparations as adjuvant therapy for diabetic kidney disease.Nov 30, 2020

Preclinical evidence of the effect of quercetin on diabetic nephropathy.Apr 14, 2022

Rosiglitazone was associated with a significant increase in the risk of myocardial infarction and with an increase in the risk of death from cardiovascular causes.Jun 14, 2007

Sulfonylureas are associated with an increased risk of adverse cardiovascular events in type 2 diabetic patients.Jun 01, 2009

TENS therapy may be an effective and safe strategy in treatment of symptomatic diabetic peripheral neuropathy.Jul 01, 2010

There is significant evidence demonstrating that Qigong may be beneficial in type 2 diabetes. Sep 01, 2005

These findings suggest that astragaloside IV is a multifaceted renoprotective candidate drug for diabetic nephropathy.Dec 31, 2019

Vegetarian dietary patterns improve cardiometabolic risk factors in diabetes.Jun 12, 2018

High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.Nov 01, 2010

The consumption of omega-3 fatty acid supplements decreases homocysteine levels in diabetic patients.Jun 01, 2010

"Sesame oil exhibits synergistic effect with anti-diabetic medication in patients with type 2 diabetes mellitus."Jun 01, 2011

3 months supplementation of ginger improved glycemic indices, TAC and PON-1 activity in patients with type 2 diabetes.Feb 09, 2015

A combination of quercetin, ascorbyl palmitate and vitamin D appears to safely offer relief of symptomatic diabetic neuropathy.Sep 01, 2005

A flaxseed-derived lignan supplement may reduce C-reactive protein in type 2 diabetics. Apr 01, 2009

A low carbohydrate diet has the potential to reduce abdominal fat and adverse lipid changes in patients with type 2 diabetes.Jan 01, 2011

A low glycemic index diet improves glycation in patients with type 2 diabetes.Jun 01, 2010

A low-carbohydrate diet is as effective as insulin therapy in faciliating glycemic control in patients with severe type 2 diabetes. Jan 01, 2009

A pilot study indicated that applying kiwifruit on neuropathic diabetic foot ulcers led to a significant reduction in the size of the foot ulcers and faster wound healing.May 31, 2014

A tea made from Roselle (Hibiscus sabdariffa) improves blood lipid profiles in patients with diabetes. Aug 01, 2009

Acetyl-l-carnitine is effective and well tolerated in improving neurophysiological parameters and in reducing pain in patients with diabetic neuropathy. Jan 01, 2002

Acetyl-l-carnitine shows promise in the treatment of diabetic peripheral neuropathy. Jan 01, 2007

Acupressure therapy inhibits the development of diabetic complications in patients with type 2 diabetes. Sep 01, 2009

Acupuncture could bring benefit as an additional treatment for people with diabetic painful neuropathy.May 31, 2014

Acupuncture has therapeutic effects on diabetic neuropathies. Mar 01, 2006

Acupuncture has therapeutic value in the treatment of diabetic peripheral neuropathy. Jun 01, 2010

Acupuncture may be clinically useful for the radical treatment of diabetic bladder dysfunction. Aug 01, 2009

Aged garlic extract reduces left ventricular myocardial mass in patients with diabetes.Jan 31, 2020

Almond ingestion at mealtime reduces postprandial glycemia and chronic ingestion reduces hemoglobin A(1c) in individuals with well-controlled type 2 diabetes mellitus.Apr 11, 2011

Alpha Lipoic Acid has therapeutic benefits in the treatment of diabetic neuropathy - Article 1Jan 01, 2008

Aromatherapy decreased the autonomic response to a painful stimulus.Aug 14, 2015

Ascorbic acid with metformin is more effective against reducing risks for diabetes related long-term complications.Aug 13, 2017

Aspirin increases mortality in diabetic patients without cardiovascular disease. Dec 01, 2009

Association of vitamin D deficiency and degree of coronary artery disease in cardiac patients with type 2 diabetes.Dec 31, 2016

Bay leaves improve glucose and lipid profile of people with type 2 diabetes.Jan 01, 2009

Benfotiamine inhibits oxidative stress with type 2 diabetes.Sep 01, 2006

Benfotiamine reduces polyneuropathy symptoms. - Article 2Feb 01, 2005

Berberine improves diabetic kidney disease by reducing UACR and serum Cys C in T2DM patients.Dec 10, 2018

Biotin improves diabetic peripheral neuropathy. Jan 01, 1990

Black cumin seeds have significant anti-diabetic effects in type 2 diabetics. Oct 01, 2010

C-reactive protein is a strong independent predictor of death in type 2 diabetes: association with multiple facets of the metabolic syndrome.Mar 01, 2006

C-reactive protein more than LDL determines cardiovascular events and mortality in hemodialysis patients with type 2 diabetes mellitus.Nov 01, 2009

Chia seed (S. hispanica) supplementation attenuates cardiovascular risk factors while maintaining good glycemic and lipid control in people with well-controlled type 2 diabetes. Nov 01, 2007

Cocoa flavanols intake benefits cognitive function in type 1 diabetes.Jun 24, 2019

Cocoa flavanols reverse vascular dysfunction in diabetics.Jun 01, 2009

Combined therapy regulates the inflammatory process and oxidative stress and contributes to immune protection on patients with T2D.May 07, 2018

Compared to placebo, the prepared saffron gel could significantly improve erectile dysfunction in diabetic patientsMay 05, 2015

Complementary homeopathic therapy of diabetic neuropathy was feasible and promising effects in symptom scores and cost savings were observed.Dec 31, 2008

CoQ10 supplementation for 12 weeks among DN patients had favorable effects on glucose metabolism, MDA, and AGEs levels.Nov 06, 2017

Cranberry extract has a favorble effect on blood lipid profiles in patients with type 2 diabetes. Dec 01, 2008

Curcumin as a major active component of turmeric attenuates proteinuria in patients with overt diabetic nephropathy.Dec 31, 2018

Date consumption (and mainly the Hallawi variety) by healthy subjects, despite their high sugar content, demonstrates beneficial effects on serum triacylglycerol and oxidative stress and does not worsen serum glucose and lipid/lipoprotein pattern. Sep 09, 2009

Early hyperbaric oxygen therapy may improve the long term neurological consequences of diabetic patients suffering from hemorrhagic stroke.Feb 22, 2017

Effect of an aqueous extract of Terminalia chebula on endothelial dysfunction, systemic inflammation, and lipid profile in type 2 diabetes mellitus.Jul 01, 2020

Effect of Oral carnosine supplementation on urinary TGF-β in diabetic nephropathy.Jun 25, 2021

Effects of resistance training using elastic bands on muscle strength with or without a leucine supplement in elderly patients with type 2 diabetes.Oct 16, 2020

Efficacy of alogliptin combined with motor imagery under hyperbaric oxygen in diabetic nephropathy with silent cerebral infarction.Oct 31, 2017

Eicosapentaenoic acid (EPA) reduces the progression of carotid intima-media thickness in patients with type 2 diabetes. Mar 01, 2007

Evaluation of therapeutic effects of crocin in attenuating the progression of diabetic nephropathy.Oct 07, 2022

Glibenclamide in combination with metformin is associated with significantly higher mortality. Nov 01, 2006

Greater intake of the MEDI diet is associated with better cognitive trajectory in older adults with type 2 diabetes.Jul 08, 2022

Diabetic Complications

View the Evidence:
1424 Abstracts with Diabetic Complications Research