Diabetic Ulcer

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45 Substances Researched for Diabetic Ulcer
NameACCKFocus
Aloe Vera533Locked
Kiwifruit220Locked
Magnesium220Locked
Probiotics415Locked
Ageratina212Locked
Honey312Locked
Vitamin D211Locked
Amino Acids110Locked
Arginine110Locked
Guduchi 110Locked
Mimosa tenuiflora110Locked
Nigella sativa (aka Black Seed)110Locked
Oxygen Therapies110Locked
Plantago major110Locked
Salt110Locked
Turmeric: Topical110Locked
Vitamin C110Locked
Vitamin E110Locked
Zinc110Locked
Hesperidin24Locked
Papaya23Locked
Rehmannia23Locked
Catechin 12Locked
Flavonoids12Locked
Frankincense12Locked
Ginseng (Korean)12Locked
Ginsenosides12Locked
Gotu Kola12Locked
Lactobacillus Acidophilus12Locked
Lactobacillus rhamnosus 12Locked
Lotus 12Locked
Nicotinamide Mononucleotide12Locked
Paeonol12Locked
Pine Bark Extract12Locked
Pycnogenol (Pine Bark)12Locked
Safflower12Locked
Sea buckthorn12Locked
Sesamol12Locked
Spinach12Locked
Turmeric12Locked
Astragalus11Locked
Beta Sitosterol11Locked
Olive Oil11Locked
Pterostilbene11Locked
Resveratrol11Locked
15 Therapeutic Actions Researched for Diabetic Ulcer
NameACCKFocus
Hyperbaric Treatment10104Locked
Photobiomodulation1049Locked
Maggot therapy220Locked
Ozone Therapy 211Locked
Balneotherapy110Locked
Electric Stimulation 110Locked
Light Therapy: Red Colored110Locked
Massage/Therapeutic Touch110Locked
Mud Therapy: Volcanic110Locked
Mud therapy 110Locked
Placebo Effect110Locked
Pulsed EMF field (PEMF)110Locked
Ultrasound therapy110Locked
Light-Emitting Diodes (LEDs) Therapy11Locked
Photodynamic therapy11Locked
Related Topics

Diabetic Ulcer is a Sub of the following Topic

View the Evidence:
82 Abstracts with Diabetic Ulcer Research

[+]

Efficacy and safety of hyperbaric oxygen therapy in the management of diabetic foot ulcers.Nov 20, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Wound J. 2023 Nov 21 ;21(3):e14507. Epub 2023 Nov 21. PMID: 37990756
Article Published Date : Nov 20, 2023
Study Type : Meta Analysis, Review
Additional Links
Diseases : Diabetic Ulcer, Foot Ulcer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Ulcer Agents
[+]

A combination of hyper-oxygenated fatty acids, Aloe barbadensis (syn. A. vera) and Mimosa tenuiflora has therapetuic benefits in the treatment of vascular ulcers and diabetic foot ulcers. Oct 01, 2006

Pubmed Data : Rev Enferm. 2006 Oct;29(10):25-30. PMID: 17144630
Article Published Date : Oct 01, 2006
Study Type : Human Study
Additional Links
Substances : Aloe Vera, Mimosa tenuiflora, Oxygen Therapies
Diseases : Diabetic Ulcer
Additional Keywords : Plant Extracts
[+]

A pilot study indicated that applying kiwifruit on neuropathic diabetic foot ulcers led to a significant reduction in the size of the foot ulcers and faster wound healing.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Res Med Sci. 2014 Jun ;19(6):520-4. PMID: 25197293
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Substances : Kiwifruit
Diseases : Diabetic Complications, Diabetic Ulcer, Wound Healing: Delayed
Pharmacological Actions : Wound Healing Effects
[+]

A. pichinchensis extract showed the ability to improve the healing process in patients with diabetic foot ulcer.Feb 28, 2015

Pubmed Data : Planta Med. 2015 Mar ;81(4):272-8. Epub 2015 Feb 25. PMID: 25714724
Article Published Date : Feb 28, 2015
Study Type : Human Study
Additional Links
Substances : Ageratina
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Antifungal Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Adjunctive hyperbaric oxygen therapy appears to improve wound healing in ischaemic diabetic foot ulcers.Dec 31, 2017

Pubmed Data : Open Cardiovasc Med J. 2018 ;12:80-85. Epub 2018 Aug 31. PMID: 30258500
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Ulcer Agents
[+]

Adjunctive Hyperbaric oxygen therapy can be valuable for treating selected cases of hypoxic diabetic foot ulcers.Mar 01, 2002

Pubmed Data : J Diabetes Complications. 2002 Mar-Apr;16(2):153-8. PMID: 12039398
Article Published Date : Mar 01, 2002
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
[+]

Adjunctive hyperbaric oxygen therapy improved wound healing in persons with diabetic foot ulcers.Sep 28, 2017

Pubmed Data : J Wound Ostomy Continence Nurs. 2017 Sep 29. Epub 2017 Sep 29. PMID: 28968346
Article Published Date : Sep 28, 2017
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
Additional Keywords : Risk Reduction
[+]

Application of a specific Abzan (salt water bath) may significantly decrease the pain of diabetic peripheral neuropathypatients.Feb 29, 2020

Pubmed Data : Complement Ther Med. 2020 Mar ;49:102325. Epub 2020 Jan 23. PMID: 32147053
Article Published Date : Feb 29, 2020
Study Type : Human Study
Additional Links
Substances : Salt
Diseases : Diabetic Ulcer, Peripheral Neuropathies
Pharmacological Actions : Analgesics
[+]

Compressed air massage improves healing of the diabetic foot. Feb 01, 2008

Pubmed Data : Diabetes Technol Ther. 2008 Feb;10(1):39-45. PMID: 18275361
Article Published Date : Feb 01, 2008
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Massage/Therapeutic Touch
[+]

Dose-response and efficacy of 904 nm photobiomodulation on diabetic foot ulcers healing.May 27, 2024

Pubmed Data : Lasers Med Sci. 2024 May 28 ;39(1):142. Epub 2024 May 28. PMID: 38805069
Article Published Date : May 27, 2024
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Effect of 660/850 nm LED on the microcirculation of the foot.Nov 30, 2021

Pubmed Data : Lasers Med Sci. 2021 Dec ;36(9):1883-1889. Epub 2021 Jan 5. PMID: 33398615
Article Published Date : Nov 30, 2021
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Ulcer Agents
[+]

Efficacy of comprehensive ozone therapy in diabetic foot ulcer healing.Jan 31, 2019

Pubmed Data : Diabetes Metab Syndr. 2019 Jan - Feb;13(1):822-825. Epub 2018 Dec 1. PMID: 30641815
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Ozone Therapy
[+]

Guduchi (Tinospora cordifolia) is an effective adjuvant therapy to surgical treatment of diabetic foot ulcer. Oct 01, 2010

Pubmed Data : Urology. 2010 Oct;76(4):841-5. PMID: 17558098
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Guduchi
Diseases : Diabetic Ulcer
Pharmacological Actions : Immunomodulatory
[+]

Home-based electrical stimulation to accelerate wound healing.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Sci Technol. 2023 Jan ;17(1):15-24. Epub 2021 Jul 30. PMID: 34328024
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Foot Ulcer, Wound Healing
Therapeutic Actions : Electric Stimulation
Pharmacological Actions : Anti-Ulcer Agents
[+]

Hyperbaric oxygen therapy has a therapeutic role in the treatment of lower-extremeity diabetic ulcers. May 01, 2007

Pubmed Data : Wound Repair Regen. 2007 May-Jun;15(3):322-31. PMID: 17537119
Article Published Date : May 01, 2007
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
[+]

Hyperbaric oxygen therapy in management of diabetic foot ulcers.Dec 31, 2020

Pubmed Data : Plast Reconstr Surg. 2021 Jan 1 ;147(1):209-214. PMID: 33370067
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Ulcer Agents
[+]

Hyperbaric oxygenation accelerates the healing rate of nonischemic chronic diabetic foot ulcers. Aug 01, 2003

Pubmed Data : Diabetes Care. 2003 Aug;26(8):2378-82. PMID: 12882865
Article Published Date : Aug 01, 2003
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
[+]

It is recommended that clinicians and wound care nurses use aloe vera gel instead of Nigella sativa oil gel for the topical treatment of diabetic ulcers.Dec 31, 2017

Pubmed Data : J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18772804. PMID: 29717629
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Aloe Vera, Nigella sativa (aka Black Seed)
Diseases : Diabetic Ulcer, Wound Healing
[+]

L-Arginine supplementation enhances diabetic wound healing. Oct 01, 2002

Pubmed Data : Metabolism. 2002 Oct;51(10):1269-73. PMID: 12370845
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Nitric Oxide Enhancer
[+]

Low-level light therapy was recognized as a potential method in the comprehensive treatment of diabetic foot ulcer.Jul 22, 2018

Pubmed Data : Diabetes Res Clin Pract. 2018 Jul 23 ;143:215-224. Epub 2018 Jul 23. PMID: 30009935
Article Published Date : Jul 22, 2018
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Photobiomodulation
[+]

Maggot debridement therapy wis a rapid, simple and efficient method of treating diabetic foot ulcers.Oct 01, 2007

Pubmed Data : J Wound Care. 2007 Oct;16(9):379-83. PMID: 17987750
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Maggot therapy
[+]

Maggot therapy is effective for infected diabetic foot ulcers refractory to conventional therapy. Feb 01, 2003

Pubmed Data : Diabetes Care. 2003 Feb;26(2):446-51. PMID: 12547878
Article Published Date : Feb 01, 2003
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Maggot therapy
Additional Keywords : Therapeutic Action Superior to Drug Therapy
[+]

Magnesium supplementation for 12 weeks among subjects with diabetic foot ulcer had beneficial effects.Jan 31, 2018

Pubmed Data : Biol Trace Elem Res. 2018 Feb ;181(2):207-215. Epub 2017 May 24. PMID: 28540570
Article Published Date : Jan 31, 2018
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

PEMF therapy seemed to accelerate wound healing and improve microcirculation.Apr 30, 2015

Pubmed Data : Adv Skin Wound Care. 2015 May ;28(5):212-9. PMID: 25882659
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Foot Ulcer, Wound Healing
Therapeutic Actions : Pulsed EMF field (PEMF)
[+]

Photobiomodulation therapy can be effectively used as a treatment mode for neuroischaemic diabetic foot ulcers in patients with type 2 diabetes.Dec 01, 2018

Pubmed Data : J Wound Care. 2018 Dec 2 ;27(12):837-842. PMID: 30557112
Article Published Date : Dec 01, 2018
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Diabetic Ulcer
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Ulcer Agents
[+]

Regeneration of diabetic foot ulcers based on therapy with red LED light and a natural latex biomembrane.Mar 31, 2019

Pubmed Data : Ann Biomed Eng. 2019 Apr ;47(4):1153-1164. Epub 2019 Feb 1. PMID: 30710185
Article Published Date : Mar 31, 2019
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Light Therapy: Red Colored
[+]

Short-duration hyperbaric oxygen therapy can improve HbA1c levels, leukocyte count, and serum creatinine levels in patients with diabetic foot ulcer.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2018 ;2018:6425857. Epub 2018 Aug 12. PMID: 30158840
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Ulcer Agents
[+]

Targeted amino acid supplementation in diabetic foot wounds.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Surg Infect (Larchmt). 2014 Dec ;15(6):708-12. PMID: 25215468
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Substances : Amino Acids
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Placebo Effect
[+]

The beneficial effects of probiotic administration on wound healing and metabolic status in patients with diabetic foot ulcer.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Metab Res Rev. 2018 Mar ;34(3). Epub 2017 Dec 21. PMID: 29193662
Article Published Date : Feb 28, 2018
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : C-Reactive Protein, Diabetic Ulcer, Insulin Resistance, Oxidative Stress, Wound Healing
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Malondialdehyde Down-regulation, Nitric Oxide Inhibitor
[+]

The effect of kiwifruit therapeutics in the treatment of diabetic foot ulcer.Feb 01, 2021

Pubmed Data : Int J Low Extrem Wounds. 2021 Feb 2:1534734619851700. Epub 2021 Feb 2. PMID: 33527863
Article Published Date : Feb 01, 2021
Study Type : Human Study
Additional Links
Substances : Kiwifruit
Diseases : Diabetic Ulcer
Pharmacological Actions : Anti-Ulcer Agents
[+]

The effects of magnesium and vitamin E co-supplementation on wound healing and metabolic status in patients with diabetic foot ulcer.Apr 30, 2019

Pubmed Data : Wound Repair Regen. 2019 May ;27(3):277-284. Epub 2019 Feb 11. PMID: 30693609
Article Published Date : Apr 30, 2019
Study Type : Human Study
Additional Links
Substances : Magnesium, Vitamin E
Diseases : Diabetic Ulcer, Foot Ulcer, Oxidative Stress, Wound Healing
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants
[+]

The effects of zinc supplementation on wound healing and metabolic status in patients with diabetic foot ulcer.Apr 30, 2017

Pubmed Data : Wound Repair Regen. 2017 May ;25(3):512-520. Epub 2017 May 9. PMID: 28395131
Article Published Date : Apr 30, 2017
Study Type : Human Study
Additional Links
Substances : Zinc
Diseases : C-Reactive Protein, Diabetic Ulcer, Foot Ulcer, Insulin Resistance, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Malondialdehyde Down-regulation
[+]

The use of honey significantly reduced rate of amputation and improved wound healing when used for a wound dressing in chronic diabetic foot ulcers.Jun 30, 2014

Pubmed Data : J Ayub Med Coll Abbottabad. 2014 Jul-Sep;26(3):304-6. PMID: 25671933
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : Diabetic Complications, Diabetic Ulcer, Wound Healing
[+]

Topical Plantavera gel seems to be an effective, cheap and safe treatment of diabetic foot ulcer.Jan 13, 2018

Pubmed Data : Curr Drug Discov Technol. 2018 01 14. Epub 2018 Jan 14. PMID: 29336265
Article Published Date : Jan 13, 2018
Study Type : Human Study
Additional Links
Substances : Aloe Vera, Plantago major
Diseases : Diabetic Ulcer
Pharmacological Actions : Anti-Ulcer Agents
[+]

Topical turmeric ointment in the treatment of diabetic foot ulcers.Dec 12, 2022

Pubmed Data : Int J Low Extrem Wounds. 2022 Dec 13:15347346221143222. Epub 2022 Dec 13. PMID: 36514270
Article Published Date : Dec 12, 2022
Study Type : Human Study
Additional Links
Substances : Turmeric: Topical
Diseases : Diabetic Ulcer
Pharmacological Actions : Anti-Ulcer Agents
[+]

Ultrasound therapy has value in treating recalcitrant diabetic foot ulcers. Aug 01, 2005

Pubmed Data : Ostomy Wound Manage. 2005 Aug;51(8):24-39. PMID: 16234574
Article Published Date : Aug 01, 2005
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Ultrasound therapy
[+]

Use of hyperbaric oxygen therapy (HBOT) in chronic diabetic wound.Sep 30, 2019

Pubmed Data : Med J Malaysia. 2019 Oct ;74(5):418-424. PMID: 31649219
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Hyperbaric Treatment
[+]

Vitamin C improves healing of foot ulcers.Nov 27, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Nutr. 2021 Nov 28 ;126(10):1451-1458. Epub 2020 Sep 28. PMID: 32981536
Article Published Date : Nov 27, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Diabetic Ulcer, Foot Ulcer, Wound Healing
Pharmacological Actions : Anti-Ulcer Agents
[+]

vitamin D supplementation had beneficial effects on improved glycemic control in patients with diabetic foot ulcer.Jun 22, 2016

Pubmed Data : J Diabetes Complications. 2016 Jun 23. Epub 2016 Jun 23. PMID: 27363929
Article Published Date : Jun 22, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : C-Reactive Protein, Diabetic Ulcer, Wound Healing: Delayed
Pharmacological Actions : Anticholesteremic Agents, Malondialdehyde Down-regulation
[+]

Volanic mud and balneotherapy treatment is effective in patients with diabetic gangrene of the lower extremities. Nov 01, 2009

Pubmed Data : Vopr Kurortol Fizioter Lech Fiz Kult. 2009 Nov-Dec(6):42-3. PMID: 20050166
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Diseases : Diabetic Ulcer, Gangrene
Therapeutic Actions : Balneotherapy, Mud therapy , Mud Therapy: Volcanic
Pharmacological Actions : Anti-Bacterial Agents
[+]

A diabetic foot ulcer was treated with hydrogel and hyperbaric oxygen therapy.Nov 01, 2017

Pubmed Data : J Wound Care. 2017 Nov 2 ;26(11):692-695. PMID: 29131751
Article Published Date : Nov 01, 2017
Study Type : Human: Case Report
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Ulcer Agents
[+]

Low-level laser therapy (LLLT) for Diabetic Foot Ulcer in Uncontrolled DiabetesJul 02, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Case Rep. 2024 Jul 3 ;25:e944106. Epub 2024 Jul 3. PMID: 38956839
Article Published Date : Jul 02, 2024
Study Type : Human: Case Report
Additional Links
Diseases : Diabetes Mellitus: Type 2, Diabetic Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

A polyherbal formula containing Sea buckthorn (H. rhamnoides), Aloe and Turmeric (C. longa) possesses significant wound healing potential in both normal as well as chronic diabetic wounds. Nov 01, 2008

Pubmed Data : Wound Repair Regen. 2008 Nov-Dec;16(6):784-90. PMID: 19128249
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Substances : Aloe Vera, Sea buckthorn, Turmeric
Diseases : Diabetic Ulcer, Wound Healing
Additional Keywords : Plant Extracts
[+]

A potential therapeutic strategy of an innovative probiotic formulation toward topical treatment of diabetic ulcer.Aug 19, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Diabetes. 2024 Aug 20 ;14(1):66. Epub 2024 Aug 20. PMID: 39164243
Article Published Date : Aug 19, 2024
Study Type : Animal Study
Additional Links
Substances : Lactobacillus Acidophilus, Lactobacillus rhamnosus , Probiotics
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Bacterial Agents
[+]

Ageratina pichinchensis consistently improve wound healing induced on the skin of rats with streptozotocin-induced diabetes.Oct 27, 2014

Pubmed Data : J Ethnopharmacol. 2014 Oct 28 ;156:222-7. Epub 2014 Sep 16. PMID: 25218321
Article Published Date : Oct 27, 2014
Study Type : Animal Study
Additional Links
Substances : Ageratina
Diseases : Diabetic Ulcer, Wound Healing
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Baicalin is a potential therapeutic candidate for a diabetic foot ulcer and chronic wounds treatment.Aug 18, 2021

Pubmed Data : J Biochem Mol Toxicol. 2021 Aug 19:e22893. Epub 2021 Aug 19. PMID: 34414639
Article Published Date : Aug 18, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Diabetic Ulcer
Pharmacological Actions : Anti-Ulcer Agents
[+]

Effect of the combination of probiotics and Korean red ginseng on diabetic wound healing exposed to diesel exhaust particles.Jun 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicina (Kaunas). 2023 Jun 15 ;59(6). Epub 2023 Jun 15. PMID: 37374359
Article Published Date : Jun 14, 2023
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean), Probiotics
Diseases : Diabetic Ulcer, Diesel Exhaust Particle Toxicity , Wound Healing
[+]

EGCG topical application improves ulcer healing time in type 2 diabetic mice. Sep 01, 2008

Pubmed Data : Wound Repair Regen. 2008 Sep-Oct;16(5):714-20. PMID: 19128267
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Catechin
Diseases : Diabetic Ulcer, Wound Healing
Additional Keywords : Reepithelialization
[+]

Ginsenoside Rg-1 promoted the wound closure of diabetic foot ulcer.May 30, 2019

Pubmed Data : Life Sci. 2019 May 31. Epub 2019 May 31. PMID: 31158376
Article Published Date : May 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Diabetic Ulcer
Pharmacological Actions : Anti-Ulcer Agents, MicroRNA modulator
[+]

Hesperidin could be used to enhance wound healing in chronic diabetic foot ulcers.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EXCLI J. 2018 ;17:399-419. Epub 2018 May 4. PMID: 29805347
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Diabetic Complications, Diabetic Ulcer, Wound Healing
Pharmacological Actions : Angiogenesis Inducing Agents, Vascular Endothelial Growth Factor C Inhibitor
[+]

Hesperidin protects against stress induced gastric ulcer.Jun 22, 2018

Pubmed Data : Chem Biol Interact. 2018 Jun 23 ;291:153-161. Epub 2018 Jun 23. PMID: 29944876
Article Published Date : Jun 22, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Diabetic Ulcer, Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Nrf2 activation
Additional Keywords : Natural Substances Versus Drugs
[+]

Impact of photobiomodulation and condition medium on mast cell counts, degranulation, and wound strength in infected skin wound healing.Oct 31, 2019

Pubmed Data : Photobiomodul Photomed Laser Surg. 2019 Nov ;37(11):706-714. Epub 2019 Oct 7. PMID: 31589095
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Diabetic Ulcer, Foot Ulcer, Staphylococcus aureus: Methicillin-resistant (MRSA), Wound Healing
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Ulcer Agents
[+]

Neferine significantly promotes a fast and efficient wound healing.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Artif Cells Nanomed Biotechnol. 2020 Dec ;48(1):96-106. PMID: 31852261
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents
[+]

Paeonol accelerates skin wound healing by regulating macrophage polarization and inflammation in diabetic rats.Aug 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2023 Sep 1 ;27(5):437-448. PMID: 37641806
Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Diabetic Ulcer, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Papaya promotes significant wound healing in diabetic rats.Aug 01, 2007

Pubmed Data : Indian J Exp Biol. 2007 Aug;45(8):739-43. PMID: 17877152
Article Published Date : Aug 01, 2007
Study Type : Animal Study
Additional Links
Substances : Papaya
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Pine bark improves healing time of Diabetic ulcers.Jul 01, 2006

Pubmed Data : Clin Appl Thromb Hemost. 2006 Jul;12(3):318-23. PMID: 16959685
Article Published Date : Jul 01, 2006
Study Type : Animal Study
Additional Links
Substances : Pine Bark Extract, Pycnogenol (Pine Bark)
Diseases : Diabetic Amyotrophy, Diabetic Ulcer
[+]

Preparation and safety evaluation of Centella asiatica total glycosides nitric oxide gel and its therapeutic effect on diabetic cutaneous ulcers.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:1419146. Epub 2022 Mar 25. PMID: 35368764
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Diabetic Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents
[+]

Rehmannia is effective in promoting diabetic foot ulcer healing in rats through the processes of tissue regeneration, angiogenesis and inflammation control. May 04, 2009

Pubmed Data : J Ethnopharmacol. 2009 May 4;123(1):155-62. Epub 2009 Feb 14. PMID: 19429355
Article Published Date : May 04, 2009
Study Type : Animal Study
Additional Links
Substances : Rehmannia
Diseases : Diabetic Ulcer, Wound Healing: Delayed
Additional Keywords : Regenerative Substances
[+]

Sesamol-loaded PLGA nanosuspension for accelerating wound healing in diabetic foot ulcer in rats.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2020 ;15:9265-9282. Epub 2020 Nov 23. PMID: 33262587
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Spinacia oleracea aqueous extract can be effective in regenerating diabetic ulcers.Apr 30, 2016

Pubmed Data : J Sci Food Agric. 2016 May ;96(7):2337-43. Epub 2015 Sep 8. PMID: 26201288
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Spinach
Diseases : Diabetic Ulcer, Wound Healing
[+]

Temperature-sensitive hydrogel dressing loaded with nicotinamide mononucleotide accelerating wound healing in diabetic mice.Oct 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2023 Nov ;167:115431. Epub 2023 Sep 8. PMID: 37688988
Article Published Date : Oct 31, 2023
Study Type : Animal Study
Additional Links
Substances : Nicotinamide Mononucleotide
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Transforming growth factor beta (TGF-β) upregulation
[+]

Topical application of Hydroxysafflor Yellow A accelerates the wound healing in streptozotocin induced T1DM.Mar 14, 2018

Pubmed Data : Eur J Pharmacol. 2018 Mar 15 ;823:72-78. Epub 2018 Feb 4. PMID: 29408092
Article Published Date : Mar 14, 2018
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Diabetes Mellitus: Type 1, Diabetic Ulcer, Wound Healing
Pharmacological Actions : Transforming growth factor beta (TGF-β) inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Wound healing potential of the standardized extract of Boswellia serrata on experimental diabetic foot ulcer.Mar 24, 2019

Pubmed Data : Planta Med. 2019 Mar 25. Epub 2019 Mar 25. PMID: 30909313
Article Published Date : Mar 24, 2019
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
[+]

A review of ozone therapy for diabetic foot ulcers.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Gas Res. 2018 Jul-Sep;8(3):111-115. Epub 2018 Sep 25. PMID: 30319766
Article Published Date : Jun 30, 2018
Study Type : Review
Additional Links
Diseases : Diabetic Complications, Diabetic Ulcer
Therapeutic Actions : Ozone Therapy
[+]

A review of phytotherapy in diabetic foot ulcers.Apr 24, 2022

Pubmed Data : J Am Nutr Assoc. 2022 Apr 25:1-15. Epub 2022 Apr 25. PMID: 35512780
Article Published Date : Apr 24, 2022
Study Type : Review
Additional Links
Substances : Papaya
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Antimicrobial, Antioxidants, Immunomodulatory
[+]

All reviewed studies have shown a positive improvement of diabetic foot ulcers using low-level light therapy.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Drugs Dermatol. 2016 Jul 1 ;15(7):843-8. PMID: 27391634
Article Published Date : Jun 30, 2016
Study Type : Review
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Photodynamic therapy
[+]

Astragalus and Rehmannia have therapeutic value in the treatment of diabetic foot ulcers. Jun 01, 2009

Pubmed Data : Phytother Res. 2009 Jun;23(6):809-15. PMID: 19148881
Article Published Date : Jun 01, 2009
Study Type : Commentary
Additional Links
Substances : Astragalus, Rehmannia
Diseases : Diabetic Ulcer
[+]

Blended fibroin/aloe gel extract film displays a biological behavior with favorable properties for delayed wound healing.Feb 20, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Omega. 2023 Feb 21 ;8(7):6813-6824. Epub 2023 Feb 7. PMID: 36844531
Article Published Date : Feb 20, 2023
Study Type : In Vitro Study
Additional Links
Substances : Aloe Vera
Diseases : Diabetic Complications, Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Ulcer Agents
[+]

Discovery of β-sitosterol's effects on molecular changes in rat diabetic wounds and its impact on angiogenesis and macrophages.Nov 27, 2023

Pubmed Data : Int Immunopharmacol. 2023 Nov 28 ;126:111283. Epub 2023 Nov 28. PMID: 38035407
Article Published Date : Nov 27, 2023
Study Type : In Vitro Study
Additional Links
Substances : Beta Sitosterol
Diseases : Diabetic Complications, Diabetic Ulcer, Wound Healing
Pharmacological Actions : Angiogenesis Inducing Agents
[+]

Effects of photobiomodulation on mitochondrial function in diabetic adipose-derived stem cells in vitro.Jan 14, 2023

Pubmed Data : Spectrochim Acta A Mol Biomol Spectrosc. 2023 Jan 15 ;285:121835. Epub 2022 Sep 11. PMID: 36116412
Article Published Date : Jan 14, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Ulcer Agents
[+]

Evaluation of efficacy of low-level laser therapy. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Lasers Med Sci. 2020 ;11(4):369-380. Epub 2020 Oct 3. PMID: 33425286
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Diseases : Bone Diseases, Breast Cancer, Burns, Carpal Tunnel Syndrome, Diabetic Ulcer, Hair Loss, Head and Neck Cancer, Skin Diseases, Tendon Injury, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Honey ointiment is safe and effective in diabetic foot ulcer. Mar 01, 2008

Pubmed Data : J Wound Care. 2008 Mar;17(3):108-10. PMID: 18376651
Article Published Date : Mar 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Honey
Diseases : Diabetic Ulcer
[+]

Low-level light therapy has significant potential to become a cost effective modality for treatment of diabetic foot ulcer.Jan 06, 2016

Pubmed Data : Wound Repair Regen. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26748691
Article Published Date : Jan 06, 2016
Study Type : Review
Additional Links
Diseases : Diabetic Ulcer
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Olive oil shows promise for wound healing of ulcers.May 31, 2024

Pubmed Data : Cutis. 2024 Jun ;113(6):260-263. PMID: 39082992
Article Published Date : May 31, 2024
Study Type : Review
Additional Links
Substances : Olive Oil
Diseases : Diabetic Ulcer, Foot Ulcer, Pressure Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents
[+]

Photobiomodulation therapy improves the growth factor and cytokine secretory profile in human type 2 diabetic fibroblasts.Aug 31, 2020

Pubmed Data : J Photochem Photobiol B. 2020 Sep ;210:111962. Epub 2020 Jul 16. PMID: 32712344
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Diabetic Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Ulcer Agents
[+]

Pterostilbene attenuates hemin-induced dysregulation of macrophage M2 polarization via Nrf2 activation in experimental hyperglycemia.Jan 19, 2023

Pubmed Data : Inflammopharmacology. 2023 Jan 20. Epub 2023 Jan 20. PMID: 36662400
Article Published Date : Jan 19, 2023
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Diabetic Ulcer, Hyperglycemia
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Nrf2 activation
[+]

Research suggests a correlation between low vitamin D levels and hard-to-heal wounds.May 31, 2021

Pubmed Data : J Wound Care. 2021 Jun 1 ;30(Sup6):S4-S10. PMID: 34120468
Article Published Date : May 31, 2021
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Diabetic Ulcer, Vitamin D Deficiency, Wound Healing
[+]

Resveratrol promotes diabetic wound healing by inhibiting notch pathway. Apr 30, 2024

Pubmed Data : J Surg Res. 2024 May ;297:63-70. Epub 2024 Mar 5. PMID: 38447337
Article Published Date : Apr 30, 2024
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Diabetic Ulcer, Foot Ulcer, Wound Healing
Pharmacological Actions : Anti-Ulcer Agents
[+]

The role of probiotics as wound healers: an overall view.May 01, 2023

Pubmed Data : J Wound Care. 2023 May 2 ;32(5):318-328. PMID: 37094922
Article Published Date : May 01, 2023
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Bacterial Agents
[+]

This review showed that honey dressing is safer for treatment of diabetic foot ulcer.Jul 31, 2016

Pubmed Data : Complement Ther Clin Pract. 2016 Aug ;24:130-3. Epub 2016 Jun 15. PMID: 27502813
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Honey
Diseases : Diabetic Ulcer, Wound Healing
[+]

This study shows that LILI stimulates Col-I synthesis in diabetic wound healing in vitro at 660 nm.Nov 30, 2012

Pubmed Data : Diabetes Technol Ther. 2012 Dec ;14(12):1110-7. Epub 2012 Oct 11. PMID: 23057714
Article Published Date : Nov 30, 2012
Study Type : In Vitro Study
Additional Links
Diseases : Diabetic Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Honey may be a safe and cost effective treatment for diabetic foot ulcers.Jul 01, 2008

Pubmed Data : WMJ. 2008 Jul;107(4):187-90. PMID: 18702435
Article Published Date : Jul 01, 2008
Additional Links
Diseases : Diabetic Ulcer

Copyright: kzenon / 123RF Stock Photo

Diabetic Ulcer Related Articles

Double-Blind Trial: Vitamin C Decreases Amputations by Half for Foot Ulcer Patients
Written by GMI Reporter
Foot ulcers and wounds often fail to heal with conventional treatment. Studies report only 30-50% of chronic foot ulcers heal with standard wound care including debridement, moist dressings, and offloading pressure.1 Up to 28% of patients with diabetic foot ulcers require amputation within 5 years.2 These poor outcomes persist despite new wound care technologies and drug trials costing billions of dollars.3

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