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8 Substances Researched for Drug Addiction
NameACCKFocus
Ayahuasca752Locked
Cannabidiol23Locked
Huperzine12Locked
Lysergic Acid Diethylamide (LSD)22Locked
Salvia divinorum22Locked
Citicoline11Locked
Psilocybin11Locked
Psychedelics:All 11Locked
1 Problem Substances Researched for Drug Addiction
NameACCKFocus
Heroin12Locked
6 Therapeutic Actions Researched for Drug Addiction
NameACCKFocus
Exercise: HIIT121Locked
Dietary Modification: Low Carbohydrate/Ketogenic110Locked
Meditation 110Locked
Qigong110Locked
Dietary Modification: Caloric Restriction 12Locked
Fasting/Caloric Restriction12Locked

View the Evidence:
20 Abstracts with Drug Addiction Research

[+]

Long-term exercise interventions for reducing drug craving in people with drug use disorder.Sep 17, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Sci (Basel). 2025 Sep 18 ;15(9). Epub 2025 Sep 18. PMID: 41009302
Article Published Date : Sep 17, 2025
Study Type : Meta Analysis, Review
Additional Links
Diseases : Drug Addiction
Therapeutic Actions : Exercise: HIIT
[+]

Ayahuasca is applicable in the treatment of drug addiction.Aug 29, 2018

Pubmed Data : J Psychoactive Drugs. 2018 Aug 30:1-7. Epub 2018 Aug 30. PMID: 30160615
Article Published Date : Aug 29, 2018
Study Type : Human Study
Additional Links
Substances : Ayahuasca
Diseases : Drug Addiction
[+]

Ayahuasca's efficacy in the treatment of addiction blends somatic, symbolic and collective dimensions.Apr 18, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Drug Policy. 2017 Apr 19 ;44:23-30. Epub 2017 Apr 19. PMID: 28432902
Article Published Date : Apr 18, 2017
Study Type : Human Study
Additional Links
Substances : Ayahuasca
Diseases : Drug Addiction
Additional Keywords : Ayahuasca, Drug Addiction, Spiritual Beliefs
[+]

Exploring ayahuasca-assisted therapy for addiction.Sep 04, 2019

Pubmed Data : Drug Alcohol Rev. 2019 Sep 5. Epub 2019 Sep 5. PMID: 31489731
Article Published Date : Sep 04, 2019
Study Type : Human Study
Additional Links
Substances : Ayahuasca
Diseases : Drug Addiction, Substance Abuse
[+]

Hypotheses regarding the mechanisms of ayahuasca in the treatment of addictions.Jun 30, 2012

Pubmed Data : J Psychoactive Drugs. 2012 Jul-Aug;44(3):200-8. PMID: 23061319
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Substances : Ayahuasca
Diseases : Alcohol Addiction, Alcohol Withdrawal, Drug Addiction
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Hypotheses regarding the mechanisms of ayahuasca in the treatment of addictions.Jun 30, 2012

Pubmed Data : J Psychoactive Drugs. 2012 Jul-Aug;44(3):200-8. PMID: 23061319
Article Published Date : Jun 30, 2012
Study Type : Human Study
Additional Links
Substances : Ayahuasca
Diseases : Alcohol Addiction, Alcohol Withdrawal, Drug Addiction
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Qigong meditation appears to contribute positively to addiction treatment outcomes, with results at least as good as those of an established stress management program.Aug 01, 2010

Pubmed Data : J Altern Complement Med. 2010 Aug;16(8):875-82. PMID: 20649456
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Diseases : Drug Addiction
Therapeutic Actions : Meditation , Qigong
[+]

This succinct analysis offers evidence of the enormous potential of a KD to treat drug addiction through the inhibition of microglial activation.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2025 ;16:1462699. Epub 2025 Jan 23. PMID: 39917617
Article Published Date : Dec 31, 2024
Study Type : Human Study
Additional Links
Diseases : Brain: Microglial Activation, Drug Addiction
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Anti-Inflammatory Agents
[+]

CBD can be considered an agent that reduces the risk of the drug relapse.Aug 31, 2017

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2017 Sep 1. Epub 2017 Sep 1. PMID: 28870635
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Drug Addiction
[+]

Food restriction may alter neurological function associated with susceptibility to addictive behavior. Jul 25, 2011

Pubmed Data : Physiol Behav. 2011 Jul 25 ;104(1):162-7. Epub 2011 Apr 28. PMID: 21530562
Article Published Date : Jul 25, 2011
Study Type : Animal Study
Additional Links
Diseases : Drug Addiction
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Huperzine A inhibits heroin-seeking behaviors induced by cue or heroin priming in rats.Jan 04, 2020

Pubmed Data : Neuroreport. 2020 08 5 ;31(11):819-824. PMID: 32576772
Article Published Date : Jan 04, 2020
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Drug Addiction
Problem Substances : Heroin
[+]

Ayahuasca may act against chronic low grade inflammation and oxidative stress via the Sig-1R which can explain its widespread therapeutic indications.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:35. Epub 2016 Mar 2. PMID: 26973523
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ayahuasca
Diseases : Drug Addiction, Inflammation, Neurologic Disorders, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Sigma-1 Receptor Agonist
Additional Keywords : Psychotherapeutic, Spiritual Experiences
Adverse Pharmacological Actions : Hypertensive
[+]

Ayahuasca may be beneficial as an antidepressant, emotional regulator, anxiolytic, and antiaddictive drug.Apr 30, 2020

Pubmed Data : Hum Psychopharmacol. 2020 May ;35(3):e2728. Epub 2020 Mar 27. PMID: 32220028
Article Published Date : Apr 30, 2020
Study Type : Review
Additional Links
Substances : Ayahuasca
Diseases : Anxiety, Depression, Drug Addiction
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Cannabidiol is an exogenous cannabinoid that acts on several neurotransmission systems involved in addiction.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Subst Abuse. 2015 ;9:33-8. Epub 2015 May 21. PMID: 26056464
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Drug Addiction
[+]

Citicoline in addictive disorders: a review of the literature.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Drug Alcohol Abuse. 2014 Jul ;40(4):262-8. Epub 2014 Jun 20. PMID: 24950234
Article Published Date : Jun 30, 2014
Study Type : Review
Additional Links
Substances : Citicoline
Diseases : Alcohol Addiction, Drug Addiction
[+]

From Hofmann to the Haight Ashbury, and into the future: the past and potential of lysergic acid diethlyamide.Dec 31, 2013

Pubmed Data : J Psychoactive Drugs. 2014 Jan-Mar;46(1):3-10. PMID: 24830180
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Alcohol Addiction, Drug Addiction, Post-Traumatic Stress Disorders (PTSD)
[+]

Pharmacokinetics and pharmacodynamics of Salvinorin A and Salvia divinorum: clinical and forensic aspects.Feb 02, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Feb 3 ;14(2). Epub 2021 Feb 3. PMID: 33546518
Article Published Date : Feb 02, 2021
Study Type : Review
Additional Links
Substances : Salvia divinorum
Diseases : Drug Addiction, Gastrointestinal Diseases, Mood Disorders, Neurological Conditions
Pharmacological Actions : Gastrointestinal Agents, Neuroprotective Agents
[+]

Psychedelic drugs-a new era in 
psychiatry?
Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dialogues Clin Neurosci. 2019 ;21(2):139-147. PMID: 31636488
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Lysergic Acid Diethylamide (LSD), Psychedelics:All
Diseases : Anxiety, Depression, Drug Addiction, Post-Traumatic Stress Disorders (PTSD)
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Salvinorin A has antinociceptive, antidepressant, in some circumstances pro-depressant and anti-addictive effects.Feb 09, 2017

Pubmed Data : Phytochemistry. 2017 Feb 10. Epub 2017 Feb 10. PMID: 28190678
Article Published Date : Feb 09, 2017
Study Type : Review
Additional Links
Substances : Salvia divinorum
Diseases : Depression, Drug Addiction
Pharmacological Actions : Antidepressive Agents, Antinoceceptive
[+]

Therapeutic effect of psilocybin in addiction.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychiatry. 2023 ;14:1134454. Epub 2023 Feb 9. PMID: 36846225
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Psilocybin
Diseases : Alcohol Addiction, Drug Addiction, Tobacco Addiction/Withdrawal

Copyright: highwaystarz / 123RF Stock Photo

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