Endometrial Neoplasms

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5 Problem Substances Researched for Endometrial Neoplasms

Name	AC	CK
Tamoxifen	4	31
Ethinyl Estradiol	1	10
Bisphenol A	1	2
Bisphenol S	1	1
Paracetamol	1	1

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

View the Evidence:
8 Abstracts with Endometrial Neoplasms Research

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14 days of .06 mg ethinyl estradiol in postmenopausal women have estrogen effects associated with increased endometrium thickness.May 01, 1996

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Pubmed Data : Geburtshilfe Frauenheilkd. 1996 May;56(5):221-5. PMID: 8768057

Article Published Date : May 01, 1996

Study Type : Human Study

Additional Links

Diseases : Endometrial Cancer, Endometrial Neoplasms

Problem Substances : Ethinyl Estradiol

Adverse Pharmacological Actions : Estrogenic

[+]

Tamoxifen causes DNA adducs in the endometrium of women. Aug 01, 2000

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Pubmed Data : Carcinogenesis. 2000 Aug;21(8):1461-7. PMID: 10910945

Article Published Date : Aug 01, 2000

Study Type : Human Study

Additional Links

Diseases : Endometrial Cancer, Endometrial Neoplasms

Additional Keywords : Drug: Tamoxifen

Problem Substances : Tamoxifen

Adverse Pharmacological Actions : Carcinogenic, Genotoxic, Mutagenic

[+]

Tamoxifen treatment for breast cancer results in one-third of all patients developing endometrial polyps, hyperplasia, metaplasia, consistent with an estrogen-agonist effect.Aug 01, 2000

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Pubmed Data : Gynecol Oncol. 2000 Aug;78(2):181-6. PMID: 10926800

Article Published Date : Aug 01, 2000

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Endometrial Cancer, Endometrial Neoplasms

Additional Keywords : Drug: Tamoxifen

Problem Substances : Tamoxifen

Adverse Pharmacological Actions : Estrogen Agonist, Estrogenic

[+]

Tamoxifen use is associated with increased risk for endomentrial polyps and cancer.Dec 01, 2005

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Pubmed Data : Gynecol Obstet Fertil. 2005 Dec;33(12):975-9. PMID: 16321556

Article Published Date : Dec 01, 2005

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Endometrial Cancer, Endometrial Neoplasms

Additional Keywords : Drug: Tamoxifen

Problem Substances : Tamoxifen

Adverse Pharmacological Actions : Carcinogen

[+]

Chronic exposure to BPA impairs steroid hormone signalling in the mouse uterus, and may contribute to the pathogenesis of uterine hyperplasia and cancer.Mar 19, 2019

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Pubmed Data : Endocrinology. 2019 Mar 20. Epub 2019 Mar 20. PMID: 30892605

Article Published Date : Mar 19, 2019

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Endometrial Cancer, Endometrial Neoplasms, Prenatal Chemical Exposures

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

[+]

Bisphenol S (4,4'-Sulfonyldiphenol) has uterotrophic properties. Jan 15, 2004

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Pubmed Data : Toxicol Lett. 2004 Jan 15 ;146(2):111-20. PMID: 14643963

Article Published Date : Jan 15, 2004

Study Type : In Vitro Study

Additional Links

Diseases : Endometrial Neoplasms

Problem Substances : Bisphenol S

Adverse Pharmacological Actions : Endocrine Disruptor: Uterus, Estrogenic, Uterotrophic

[+]

Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Theranostics. 2017 ;7(7):1890-1900. Epub 2017 Apr 10. PMID: 28638475

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Diseases : Chemotherapy-Induced Toxicity: Tamoxifen, Endometrial Neoplasms

Problem Substances : Tamoxifen

[+]

Tamoxifen is genotoxic and carcinogenic to endometrial cells.May 01, 2004

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Pubmed Data : Drug Metab Rev. 2004 May;36(2):199-218. PMID: 15237851

Article Published Date : May 01, 2004

Study Type : In Vitro Study

Additional Links

Diseases : Endometrial Cancer, Endometrial Neoplasms

Additional Keywords : Drug: Tamoxifen

Problem Substances : Paracetamol

Adverse Pharmacological Actions : Genotoxic, Mutagenic

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 8 Abstracts with Endometrial Neoplasms Research

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14 days of .06 mg ethinyl estradiol in postmenopausal women have estrogen effects associated with increased endometrium thickness.May 01, 1996

Tamoxifen causes DNA adducs in the endometrium of women. Aug 01, 2000

Tamoxifen treatment for breast cancer results in one-third of all patients developing endometrial polyps, hyperplasia, metaplasia, consistent with an estrogen-agonist effect.Aug 01, 2000

Tamoxifen use is associated with increased risk for endomentrial polyps and cancer.Dec 01, 2005

Chronic exposure to BPA impairs steroid hormone signalling in the mouse uterus, and may contribute to the pathogenesis of uterine hyperplasia and cancer.Mar 19, 2019

Bisphenol S (4,4'-Sulfonyldiphenol) has uterotrophic properties. Jan 15, 2004

Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasia.Dec 31, 2016

Tamoxifen is genotoxic and carcinogenic to endometrial cells.May 01, 2004

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Endometrial Neoplasms

View the Evidence:
8 Abstracts with Endometrial Neoplasms Research