Endotoxemia

Name	AC	CK
Yoghurt	3	30
Probiotics	4	23
Pomegranate	2	20
Flavonoids	7	18
Curcumin	9	17
Resveratrol	5	17
Green Tea	3	14
Anthocyanins	2	12
Genistein	2	12
Polyphenols	5	12
Caffeine	1	10
Fermented Foods and Beverages	1	10
Flaxseed	1	10
Hops	1	10
L-Carnitine	1	10
Olive Oil	1	10
Xanthohumol	1	10
EGCG (Epigallocatechin gallate)	3	5
Vitamin D	1	5
Cannabidiol	2	4
Cannabis	2	4
Cyanidin	2	4
Fucoidan	2	4
Ginger	2	4
Hydrogen: Molecular	2	4
Lactobacillus plantarum	2	4
Lactoferrin	3	4
Paeoniflorin	2	4
Sesame Seeds	2	4
Stilbenes	2	4
6-Shogaol	1	3
Beta-Elemene	2	3
Melatonin	2	3
Nicotinamide Mononucleotide	1	3
Paeonol	2	3
Angelica	1	2
Berries: All	1	2
Bifidobacterium Breve	1	2
Bifidobacterium Longum	1	2
Black Pepper	1	2
Blueberry	1	2
Borage Oil	1	2
Caffeic acid phenethyl ester	1	2
Celastrol	1	2
Chinese Skullcap	1	2
Chlorella (Algae)	1	2
Cinnamaldehyde	1	2
Citrulline	1	2
Cloudberry	1	2
Crowberry	1	2
Delphinidin	1	2
Diosmetin	1	2
EPA (Eicosapentaenoic Acid)	1	2
Egg	1	2
Evodia ruteacarpa	1	2
Fish Oil	1	2
Grape Seed Extract	1	2
Guduchi	1	2
Honeysuckle	1	2
Horse Chestnut	1	2
Hydrogen Water	1	2
Inositol Hexaphosphate	1	2
Lactobacillus casei	1	2
Lactobacillus fermentum	1	2
Ligusticum wallichii	1	2
Lingonberry	1	2
Mulberry	1	2
Naringenin	1	2
Orange	1	2
Piceatannol	1	2
Piperine	1	2
Piperlongumine	1	2
Prunella vulgaris	1	2
Red Marine Algae	1	2
Sesame Seed Oil	1	2
Sesamol	1	2
Silibinin	1	2
Sinomenine	1	2
Tea	1	2
Thymoquinone	1	2
Vitamin B-12	1	2
Vitamin B-12: Hydroxocobalamin	1	2
Water: Deuterium Depleted	1	2
Whey	1	2
Apple Pectin	1	1
Beet	1	1
Carnosol	1	1
Colostrum	1	1
Garlic	1	1
Krill	1	1
Maitake Mushroom	1	1
Modified Citrus Pectin	1	1
Organosulfur Compounds	1	1
Pectin	1	1
Prebiotics	1	1
Rose	1	1
Sea buckthorn	1	1
Blackberry	1	0

Name	AC	CK
Fructose	2	4
Antibiotics	1	2
StarLink GM Corn (Cry9C)	2	2

Name	AC	CK
Exercise	2	12
Electroacupuncture	1	3
Photobiomodulation	1	2
Dietary Modification: Mediterranean Diet	1	1

Name	AC	CK
Western Diet	2	4
Genetically Modified Organisms	3	3
Vaccination: All	1	2
Vaccination: Diphtheria-Pertussis-Tetanus	1	1

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A green tea extract confection decreases circulating endotoxin and fasting glucose by improving gut barrier function but without affecting systemic inflammation.Mar 31, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Res. 2024 Apr ;124:94-110. Epub 2024 Feb 5. PMID: 38430822

Article Published Date : Mar 31, 2024

Study Type : Human Study

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Substances : Green Tea

Diseases : Endotoxemia, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Hypoglycemic Agents

Additional Keywords : Plant Extracts

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A Xanthohumol-rich hop extract diminishes endotoxin-induced activation of TLR4 Signaling in human peripheral blood mononuclear cells.Oct 20, 2022

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Pubmed Data : Int J Mol Sci. 2022 Oct 21 ;23(20). Epub 2022 Oct 21. PMID: 36293555

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Pubmed Data : Invest Ophthalmol Vis Sci. 2025 Jul 1 ;66(9):43. PMID: 40662891

Article Published Date : Jun 30, 2025

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : 6-Shogaol

Diseases : Endotoxemia, Lipopolysaccharide-Induced Toxicity, Uveitis

Pharmacological Actions : Anti-Inflammatory Agents, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Electroacupuncture pretreatment maintains mitochondrial quality control via HO-1/MIC60 signaling pathway to alleviate endotoxin-induced acute lung injury.Aug 29, 2024

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Pubmed Data : Biochim Biophys Acta Mol Basis Dis. 2024 Aug 30 ;1870(8):167480. Epub 2024 Aug 30. PMID: 39209235

Article Published Date : Aug 29, 2024

Study Type : Animal Study, In Vitro Study

Additional Links

Diseases : Endotoxemia, Lung Damage

Therapeutic Actions : Electroacupuncture

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Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury.Nov 30, 2024

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Additional Keywords : Microbiota

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Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.Dec 31, 2017

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Pubmed Data : Diabetologia. 2018 04 ;61(4):919-931. Epub 2017 Dec 21. PMID: 29270816

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Pubmed Data : Immunopharmacol Immunotoxicol. 2017 Oct ;39(5):296-304. Epub 2017 Aug 1. PMID: 28762847

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Pubmed Data : J Pharm Pharmacol. 2002 Oct;54(10):1399-405. PMID: 12396303

Article Published Date : Oct 01, 2002

Study Type : Animal Study

Additional Links

Substances : Evodia ruteacarpa

Diseases : Endotoxemia

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Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses.Sep 19, 2017

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Pubmed Data : Sci Rep. 2017 Sep 20 ;7(1):11977. Epub 2017 Sep 20. PMID: 28931917

Article Published Date : Sep 19, 2017

Study Type : Animal Study

Additional Links

Diseases : Endotoxemia, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

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Flos Lonicera ameliorates obesity and associated endotoxemia.Dec 31, 2013

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Pubmed Data : PLoS One. 2014 ;9(1):e86117. Epub 2014 Jan 24. PMID: 24475077

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Pubmed Data : Nutrients. 2019 Apr 29 ;11(5). Epub 2019 Apr 29. PMID: 31035432

Article Published Date : Apr 28, 2019

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Endotoxemia

Pharmacological Actions : Gastroprotective

Additional Keywords : Proanthocyanidins

Anti Therapeutic Actions : Western Diet

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Pubmed Data : Nutr Res. 2019 Mar 20. Epub 2019 Mar 20. PMID: 30982555

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Pubmed Data : J Med Food. 2019 Mar 15. Epub 2019 Mar 15. PMID: 30874461

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Sesame Seed Oil

Diseases : Endotoxemia

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These results indicated that paeonol has protective effects on endotoxin-induced kidney injury.Jun 27, 2016

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Pubmed Data : Oncotarget. 2016 Jun 28 ;7(26):39497-39510. PMID: 27027358

Article Published Date : Jun 27, 2016

Study Type : Animal Study

Additional Links

Substances : Paeonol

Diseases : Endotoxemia, Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Renoprotective

[+]

This experimental study revealed that CAPE administration significantly prevented alveolar bone loss and stimulated periodontal tissue healing.Nov 30, 2019

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Pubmed Data : Toxicol Appl Pharmacol. 2017 08 15 ;329:202-211. Epub 2017 Jun 10. PMID: 28610995

Article Published Date : Jan 14, 2017

Study Type : Animal Study

Additional Links

Substances : Ginger, Polyphenols

Diseases : Endotoxemia, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Zingerone therapy significantly protected liver from endotoxin induced inflammatory damageDec 31, 2013

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Pubmed Data : PLoS One. 2014 ;9(9):e106536. Epub 2014 Sep 3. PMID: 25184525

Pubmed Data : Int J Clin Pharmacol Ther. 2008 May;46(5):211-25. PMID: 18538107

Article Published Date : May 01, 2008

Study Type : Review

Additional Links

Substances : Colostrum

Diseases : Bacterial Infections and Mycoses, Endotoxemia, Septic Shock

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Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseasesApr 19, 2020

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Pubmed Data : Fundam Clin Pharmacol. 2014 Jun ;28(3):268-76. Epub 2013 Feb 17. PMID: 23413967

Article Published Date : May 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Paeonol

Diseases : Endotoxemia, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pinostrobin ameliorates lipopolysaccharide (LPS)-induced inflammation and endotoxemia.Nov 30, 2022

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Pubmed Data : Biomed Pharmacother. 2022 Dec ;156:113874. Epub 2022 Oct 18. PMID: 36270256

Article Published Date : Nov 30, 2022

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Endotoxemia, Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

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Suppression of cotton bollworm in multiple crops in China in areas with Bt toxin-containing cotton.Sep 18, 2008

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Pubmed Data : Science. 2008 Sep 19 ;321(5896):1676-8. PMID: 18801998

Article Published Date : Sep 18, 2008

Study Type : Review

Additional Links

Diseases : Endotoxemia

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The flavonoids of Rosa roxburghii Tratt alleviate endotoxemia progression.Sep 22, 2025

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Pubmed Data : Int Immunopharmacol. 2025 Sep 23 ;162:115159. Epub 2025 Jul 5. PMID: 40617042

Article Published Date : Sep 22, 2025

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids, Rose

Diseases : Endotoxemia, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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There may be a link between endometriosis and xenobiotics-associated genetically modified food. Dec 01, 2010

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Pubmed Data : Gynecol Obstet Fertil. 2010 Dec;38(12):747-53. PMID: 21111655

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View the Evidence: 132 Abstracts with Endotoxemia Research

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A green tea extract confection decreases circulating endotoxin and fasting glucose by improving gut barrier function but without affecting systemic inflammation.Mar 31, 2024

A Xanthohumol-rich hop extract diminishes endotoxin-induced activation of TLR4 Signaling in human peripheral blood mononuclear cells.Oct 20, 2022

Association of endotoxemia with low-grade inflammation, metabolic syndrome and distinct response to lipopolysaccharide in type 1 diabetes.Dec 09, 2023

Brown and golden flaxseed reduce intestinal permeability and endotoxemia, and improve the lipid profile.Aug 31, 2022

Caffeine optimizes HIIT benefits on obesity-associated metabolic adversity in women.Jul 31, 2020

Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.May 16, 2018

Consumption of pomegranate extract decreased endotoxemia in overweight-obese individuals by reshaping the gut microbiota.May 31, 2018

Cyanidin and delphinidin exerted beneficial actions against unhealthy diets.Apr 30, 2022

Exercise training improves gut microbiota profiles and reduces endotoxemia.Aug 15, 2019

Extra virgin olive oil reduces gut permeability and metabolic endotoxemia in diabetic patients.May 20, 2022

Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects. Dec 31, 2019

L-Carnitine and synbiotic co-supplementation: beneficial effects on metabolic-endotoxemia.Feb 20, 2023

Low-fat yogurt for 9 weeks reduced biomarkers of chronic inflammation and endotoxin exposure in premenopausal women.Nov 30, 2017

Probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.Jan 01, 2009

Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.Jun 23, 2022

Yogurt consumption improved postprandial metabolism and biomarkers of metabolic endotoxemia in healthy premenopausal women.May 14, 2018

Vitamin D attenuates human gingival fibroblast inflammatory cytokine production following advanced glycation end product interaction with receptors for AGE.Mar 31, 2019

6-shogaol alleviates endotoxin-induced uveitis.Jun 30, 2025

Electroacupuncture pretreatment maintains mitochondrial quality control via HO-1/MIC60 signaling pathway to alleviate endotoxin-induced acute lung injury.Aug 29, 2024

Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury.Nov 30, 2024

Salidroside attenuates LPS-induced acute lung injury.Sep 30, 2017

Salidroside suppressing LPS-induced myocardial injury.Nov 30, 2017

"Fucoidan enhances the survival and sustains the number of splenic dendritic cells in mouse endotoxemia."Mar 31, 2011

"Fucoidan extracted from Fucus evanescens brown algae corrects immunity and hemostasis disorders in experimental endotoxemia."Dec 31, 2008

Acacetin attenuates mice endotoxin-induced acute lung injury via augmentation of heme oxygenase-1 activity.Mar 31, 2018

Administration of Chlorella sp. microalgae reduces endotoxemia, intestinal oxidative stress and bacterial translocation in experimental biliary obstruction.Dec 01, 2009

Angelica sinensis protects mice against lethal endotoxemia and sepsis.Feb 01, 2006

Anthocyanin improves glucose homeostasis in obese mice.May 31, 2019

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.Dec 31, 2017

Baicalein, a compound found within Chinese skullcap, protects gainst endotoxic shock in rats in vivo and in vitro. Mar 15, 2007

Cannabidiol has a neuroprotective effect in endotoxin-induced uveitis. Jan 01, 2008

Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect.Jan 19, 2022

Cinnamaldehyde has a protective effect in the endotoxin poisoned mice through the inhibition of NLRP3 inflammasome activation.Sep 30, 2017

Citrulline malate has a beneficial effect on skeletal muscle function in the endotoxemic rat.Jan 05, 2009

Correction of metabolic processes in rats during chronic endotoxicosis.Dec 31, 2014

Cortex Mori and its active component mulberroside A could ameliorate diabetic endotoxemia by preserving gut integrity.Dec 31, 2020

Curcumin administration could be used as supplementary therapeutic intervention at early stage of endotoxemia.Mar 12, 2017

Curcumin ameliorates endotoxin-induced experimental hepatoxicity in rodents.Aug 01, 2006

Curcumin attenuates the organ dysfunction caused by endotoxemia in the rat.Nov 01, 2008

Curcumin improves vascular function and alleviates oxidative stress in endotoxaemia in mice.Mar 01, 2008

Curcumin inhibits liver injury in a mouse model of endotoxemic shock.Feb 01, 2010

Curcumin protects against endotoxin-induced acute liver injury in rats.Jan 01, 2006

Curcuminoids may suppress liver inflammation associated with endotoxemia. May 01, 2002

Cyanidin ameliorates endotoxin-induced myocardial toxicity.Sep 30, 2018

Dietary fish oil and fish and borage oil suppress intrapulmonary inflammation and attenuate pulmonary neutrophil accumulation in endotoxic rats.Jul 01, 1997

Dietary supplementation of sesaminol may lower the risk of ethanol-related-colorectal cancer.Sep 21, 2022

Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure.May 08, 2017

Effects of hydrogen-rich saline on endotoxin-induced uveitis.Dec 31, 2016

Endotoxemia with vaccination resulted in significanyt behavioral alterations in concomitance with an increase in biomarkers for oxidative stress and inflammation. This was not attentuated by paracetamol.Aug 01, 2018

Escin increases the survival rate of LPS-induced septic mice.Dec 31, 2014

Evodia rutaecarpa protects against circulation failure and organ dysfunction in endotoxaemic rats.Oct 01, 2002

Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses.Sep 19, 2017

Flos Lonicera ameliorates obesity and associated endotoxemia.Dec 31, 2013

Fructose is used to induce fatty liver disease in an animal model and may contribute to endotoxemiea. Dec 01, 2010

Genistein protects against septic shock in a rat model. Oct 01, 2010

Grape-seed proanthocyanidins are able to reverse intestinal dysfunction and metabolic endotoxemia induced by a cafeteria diet.Apr 28, 2019

Green tea extract catechins protect against NF-κB-mediated liver injury in nonalcoholic steatohepatitis.Sep 30, 2019

Green tea rescues mice from lethal endotoxemia and sepsis.Nov 07, 2007

Hirsutanol A could be a useful agent for treating inflammatory diseases.Jun 16, 2019

Hydroxocobalamin (vitamin B12a) prevents and reverses endotoxin-induced hypotension and mortality in rodents.Apr 01, 1995

Inositol hexaphosphate protects the mouse liver against endotoxemia.Jan 01, 2007

Intestinal dysbios is a possible causative factor in alcohol-incuded endotoxemia and alcoholic fatty liver in rats. Oct 01, 2009

L. plantarum has both preventive and therapeutic values in treatment of alcohol-induced tissue injury.Jun 17, 2018

L. plantarum LC27 and B. longum LC67 simultaneously alleviate high-fat diet-induced colitis, endotoxemia, liver steatosis, and obesity.Mar 19, 2019

Lactobacillus casei beneficially modulates immuno-coagulative response in an endotoxemia model.Nov 26, 2017

Lactoferrin suppresses lipopolysaccharide-induced endometritis in mice via down-regulation of the NF-κB pathway.Aug 31, 2015

Loss of intestinal Serotonin reuptake transporter (SERT) is a critical factor in fructose-induced impairment of intestinal barrier function and subsequently the development of steatosis.Mar 01, 2010

Low power laser irradiation can modulate immune-responses depending on the immunological status of the organism.Dec 31, 1996

Melatonin pretreatment modulates anti-inflammatory, antioxidant, YKL-40, and matrix metalloproteinases in endotoxemic rat lung tissue.Apr 01, 2022

Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation.Dec 31, 2018

Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin induced toxicity.Apr 01, 2010

Paeoniflorin effectively improved cardiac function during endotoxemia.Apr 30, 2016

Endotoxemia

View the Evidence:
132 Abstracts with Endotoxemia Research