Estrogen Dominance

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40 Substances Researched for Estrogen Dominance

Name	AC	CK
Soy	2	20
Seaweed	2	12
Fiber	1	10
Sesamin	1	10
phytoestrogens	1	10
Isoflavones	4	5
Lignans	3	4
Berries: All	2	3
Ellagic Acid	2	3
Genistein	3	3
Resveratrol	3	3
Blueberry	1	2
Curcumin	2	2
Enterodiol	2	2
Flavonoids	2	2
Kelp	1	2
Raspberry	1	2
Rosemary	1	2
Rye	1	2
Seaweed: Brown	1	2
Biochanin A	1	1
Blackberry	1	1
Brussel sprouts	1	1
Cabbage	1	1
Coffee	1	1
Daidzein	1	1
Damiana	1	1
Enterolactone	1	1
Euonymus alatus (Burning Bush)	1	1
Indole-3-Carbinol	1	1
Ipriflavone	1	1
Licorice	1	1
Mangosteen	1	1
Melatonin	1	1
NAC (N-acetyl-L-cysteine)	1	1
Pomegranate	1	1
Sculletaria barbata	1	1
Stilbenes	1	1
Vitamin D	1	1
Yerba Mate	1	1

19 Problem Substances Researched for Estrogen Dominance

Name	AC	CK
17beta-estradiol	2	11
Triclosan	1	2
Aluminum	1	1
Antimony	1	1
Arsenite	1	1
Barium	1	1
Cadmium	1	1
Chromium Chloride	1	1
Cobalt	1	1
Industrial Copper (inorganic)	1	1
Lead	1	1
Mercury	1	1
Mycoestrogens	1	1
Polychlorinated biphenyls (PCBs)	1	1
Selenite	1	1
Tamoxifen	1	1
Tin	1	1
Vanadate	1	1
Zearalenone (ZEA)	1	1

2 Therapeutic Actions Researched for Estrogen Dominance

Name	AC	CK	Focus
Dietary Modification: Low Fat Diet	1	10
Placebo Effect	1	10

Research Articles 39
Cumulative Knowledge Score 63
Overall Research Rating GOOD

View the Evidence:
39 Abstracts with Estrogen Dominance Research

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[+]

A very low fat, high fiber diet in healthy premenopausal women can reduce estradiol and estrone levels without affecting ovulation, thereby providing a rationale for the prevention of breast cancer through a very low fat, high fiber diet.Dec 15, 1995

Click here to read the entire abstract

Pubmed Data : Cancer. 1995 Dec 15;76(12):2491-6. PMID: 8625075

Article Published Date : Dec 15, 1995

Study Type : Human Study

Additional Links

Substances : Fiber

Diseases : Breast Cancer: Prevention, Estrogen Dominance

Therapeutic Actions : Dietary Modification: Low Fat Diet

Pharmacological Actions : Chemopreventive

[+]

Breast cancer survivors who use estrogenic botanical supplements have lower serum estrogen levels than non users.Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Breast Cancer Res Treat. 2009 Sep;117(1):111-9. Epub 2008 Oct 18. PMID: 18931907

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : phytoestrogens

Diseases : Breast Cancer, Estrogen Dominance

[+]

Dietary seeweed favorably alters phytoestrogen metabolism with a likely positive change in colonic bacteria in healthy postmenopausal women. May 01, 2009

Click here to read the entire abstract

Pubmed Data : J Nutr. 2009 May;139(5):939-44. Epub 2009 Mar 25. PMID: 19321575

Article Published Date : May 01, 2009

Study Type : Human Study

Additional Links

Substances : Seaweed

Diseases : Estrogen Dominance

Additional Keywords : Estrogen Metabolism

[+]

Estradiol may have proinflammatory effects in older men with coronary artery disease.Dec 01, 2010

Click here to read the entire abstract

Pubmed Data : Med Sci Monit. 2010 Dec;16(12):CR593-7. PMID: 21119577

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Diseases : C-Reactive Protein, Coronary Artery Disease, Estrogen Dominance

Additional Keywords : Sex Hormone-Binding Globulin

[+]

Higher estradiol levels are associated with gynecomastia.Nov 02, 1984

Click here to read the entire abstract

Pubmed Data : Dtsch Med Wochenschr. 1984 Nov 2 ;109(44):1678-82. PMID: 6489180

Article Published Date : Nov 02, 1984

Study Type : Human Study

Additional Links

Diseases : Estrogen Dominance, Gynecomastia

Additional Keywords : Diseases that are Linked, Drug: Tamoxifen

Problem Substances : 17beta-estradiol

[+]

Safety: soy food consumption lowers estrogen levels in nipple aspirate fluid and serum. Jul 08, 2011

Click here to read the entire abstract

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2011 Jul 8. Epub 2011 Jul 8. PMID: 21742946

Article Published Date : Jul 08, 2011

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Estrogen Dominance

Additional Keywords : Soy: Positive Data

[+]

Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal womenApr 30, 2006

Click here to read the entire abstract

Pubmed Data : J Nutr. 2006 May ;136(5):1270-5. PMID: 16614415

Article Published Date : Apr 30, 2006

Study Type : Human Study

Additional Links

Substances : Sesamin

Diseases : Estrogen Dominance

Therapeutic Actions : Placebo Effect

Pharmacological Actions : Antioxidants

Additional Keywords : 2-hydroxyestrone, Sex Hormone-Binding Globulin

[+]

Soy product intake is inversely associated with serum androgen and estrogen concentrations in Japanese men. Jan 01, 2000

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2000;36(1):14-8. PMID: 10798211

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Estradiol: Too High, Estrogen Dominance, Testosterone: Too High

Additional Keywords : Sex Hormone-Binding Globulin

[+]

Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism.Jun 01, 2010

Click here to read the entire abstract

Pubmed Data : Cancer Prev Res (Phila Pa). 2010 Jun;3(6):727-37. Epub 2010 May 25. PMID: 20501861

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Berries: All, Blueberry, Ellagic Acid, Raspberry

Diseases : Breast Cancer, Estrogen Dominance, Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios

Pharmacological Actions : Chemopreventive, Estradiol Antagonists

[+]

Brown kelp exhibits anti-estrogenic activity and mildly increases progesterone levels in female rats.Feb 01, 2005

Click here to read the entire abstract

Pubmed Data : J Nutr. 2005 Feb;135(2):296-300. PMID: 15671230

Article Published Date : Feb 01, 2005

Study Type : Animal Study

Additional Links

Substances : Seaweed: Brown

Diseases : Estrogen Dominance, Progesterone: Low

Pharmacological Actions : Secretagogue

Additional Keywords : Hormone Dependent Cancers

[+]

Consumption of bladderwrack results in an increase in the length of the menstrual cycle, and has significant anti-estrogenic and progestagenic effects.Aug 04, 2004

Click here to read the entire abstract

Pubmed Data : BMC Complement Altern Med. 2004 Aug 4;4:10. Epub 2004 Aug 4. PMID: 15294021

Article Published Date : Aug 04, 2004

Study Type : Animal Study

Additional Links

Substances : Kelp, Seaweed

Diseases : Estrogen Dominance, Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios, Menstruation Disorders, Menstruation Disturbances

Pharmacological Actions : Anti-Estrogenic, Progestagenic

[+]

Rosemary leaves enhance the metabolism of endogenous estrogens and decreases their uterotropic effect in mice. Oct 01, 1998

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 1998 Oct;19(10):1821-7. PMID: 9806165

Article Published Date : Oct 01, 1998

Study Type : Animal Study

Additional Links

Substances : Rosemary

Diseases : Endometrial Cancer, Estrogen Dominance, Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios, Fibroids: Uterine, Uterine Cancer

Additional Keywords : Plant Extracts

[+]

Rye lignan reduces estradiol-induced uterine growth.Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2009 Aug;53(8):996-1006. PMID: 19603405

Article Published Date : Aug 01, 2009

Study Type : Animal Study

Additional Links

Substances : Isoflavones, Lignans, Rye

Diseases : Estrogen Dominance, Uterine Cancer

[+]

Triclosan is an endocrine disruptor which exhibits estrogen disruptive and thyroid suppressive activity in rats.Sep 01, 2010

Click here to read the entire abstract

Pubmed Data : Toxicol Sci. 2010 Sep;117(1):45-53. Epub 2010 Jun 18. PMID: 20562219

Article Published Date : Sep 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Estrogen Dominance, Hormonal Disorders: Children, Hypothyroidism, Sexual Dysfunction

Problem Substances : Triclosan

Adverse Pharmacological Actions : Thyroid Suppressive

[+]

A wide range of metals have been identified to have estrogenic properties.May 01, 2006

Click here to read the entire abstract

Pubmed Data : J Appl Toxicol. 2006 May-Jun;26(3):191-7. PMID: 16489580

Article Published Date : May 01, 2006

Study Type : Review

Additional Links

Diseases : Cancers: Estrogen Responsive, Estrogen Dominance, Heavy Metal Toxicity

Additional Keywords : Metalloestrogens

Problem Substances : Aluminum, Antimony, Arsenite, Barium, Cadmium, Chromium Chloride, Cobalt, Industrial Copper (inorganic), Lead, Mercury, Selenite, Tin, Vanadate

Adverse Pharmacological Actions : Estrogenic

[+]

Berry components prevent oxidative damage to DNA caused by estradiol (E2) and copper chloride, in vitro. Sep 01, 2002

Click here to read the entire abstract

Pubmed Data : J Am Soc Nephrol. 2002 Sep;13(9):2299-308. PMID: 19003579

Article Published Date : Sep 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Berries: All, Blackberry, Ellagic Acid

Diseases : DNA damage, Estrogen Dominance, Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios

[+]

Cabbage and brussel sprouts act bifunctionally, like an antiestrogen at low concentrations and an estrogen agonist at high concentrations.Oct 01, 2000

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2000 Oct;48(10):4628-34. PMID: 11052710

Article Published Date : Oct 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : Brussel sprouts, Cabbage

Diseases : Estrogen Dominance

[+]

Coffee consumption may reduce colon cancer incidence by increasing the sulfation of estrogen.Oct 01, 2006

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2006 Oct;17(10):697-706. Epub 2006 Jan 9. PMID: 18981586

Article Published Date : Oct 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Coffee

Diseases : Colon Cancer, Estrogen Dominance

Pharmacological Actions : Detoxifier

[+]

Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Mol Cell Biochem. 2011 Jan;347(1-2):1-11. Epub 2010 Oct 13. PMID: 20941532

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cervical Cancer, Estrogen Dominance

Pharmacological Actions : Apoptotic

[+]

Damiana contains compounds with anti-aromatase activity. Dec 08, 2008

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol.2008 Dec 8;120(3):387-93. Epub 2008 Sep 26. PMID: 18948180

Article Published Date : Dec 08, 2008

Study Type : In Vitro Study

Additional Links

Substances : Damiana

Diseases : Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

[+]

Estrogen dominance (excess or unopposed estradiol) may contribute to Raynaud's phenomenon. Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1955-61. Epub 2007 Jul 20. PMID: 17644575

Article Published Date : Sep 01, 2007

Study Type : In Vitro Study

Additional Links

Diseases : Estrogen Dominance, Raynaud Disease

[+]

Euonymus altaus and Scutellaria barbarata have prowerful aromatase inhibiting properties.Aug 01, 2004

Click here to read the entire abstract

Pubmed Data : Immunopharmacol Immunotoxicol. 2004 Aug;26(3):315-27. PMID: 15518167

Article Published Date : Aug 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Euonymus alatus (Burning Bush), Sculletaria barbata

Diseases : Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

[+]

Genistein suppresses estradiol-induced uterine leiomyoma cell proliferation.Dec 31, 2004

Click here to read the entire abstract

Pubmed Data : Life Sci. 2004 Dec 31;76(7):775-82. PMID: 19903033

Article Published Date : Dec 31, 2004

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Estrogen Dominance, Leiomyoma

[+]

Indole-3 carbinol is a negative regulator of estrogen. Jul 01, 2003

Click here to read the entire abstract

Pubmed Data : J Nutr. 2003 Jul;133(7 Suppl):2470S-2475S. PMID: 12840226

Article Published Date : Jul 01, 2003

Study Type : Commentary

Additional Links

Substances : Indole-3-Carbinol

Diseases : Estrogen Dominance

[+]

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.Sep 30, 1998

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Endocrinology. 1998 Oct ;139(10):4252-63. PMID: 9751507

Article Published Date : Sep 30, 1998

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids, Isoflavones

Diseases : Estrogen Dominance

Problem Substances : Mycoestrogens, Polychlorinated biphenyls (PCBs), Zearalenone (ZEA)

Adverse Pharmacological Actions : Endocrine Disruptor

[+]

Ipriflavone accelerates clearance of estradiol (E2) through enhancing the activity of the enzyme estradiol 3-glucuronide. Nov 01, 2004

Click here to read the entire abstract

Pubmed Data : Biol Pharm Bull. 2004 Nov;27(11):1844-9. PMID: 15516735

Article Published Date : Nov 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Ipriflavone

Diseases : Estrogen Dominance, Gynecomastia

Pharmacological Actions : Estradiol 3-glucuronide enhancer

[+]

Licorice contains a compound (liquiritigenin) with aromatase inhibitory action 10 times more potent than the first generation aromatase inhibitor aminoglutethimide (Cytadren). Sep 15, 2008

Click here to read the entire abstract

Pubmed Data : Bioorg Med Chem. 2008 Sep 15;16(18):8466-70. Epub 2008 Aug 19. PMID: 18778944

Article Published Date : Sep 15, 2008

Study Type : In Vitro Study

Additional Links

Substances : Licorice

Diseases : Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

Lignans and flavonoids act as aromatase inhibitors in human preadipocytes. Aug 01, 1994

Click here to read the entire abstract

Pubmed Data : J Steroid Biochem Mol Biol. 1994 Aug;50(3-4):205-12. PMID: 8049151

Article Published Date : Aug 01, 1994

Study Type : In Vitro Study

Additional Links

Substances : Enterodiol, Flavonoids, Lignans

Diseases : Breast Cancer, Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

[+]

Mammalian lignans and the soy isoflavone genistein inhibit breast cancer via down-regulation of estrogen production. Apr 01, 2005

Click here to read the entire abstract

Pubmed Data : J Steroid Biochem Mol Biol. 2005 Apr;94(5):461-7. Epub 2005 Mar 16. PMID: 15876411

Article Published Date : Apr 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Enterodiol, Enterolactone, Genistein, Lignans

Diseases : Breast Cancer, Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

[+]

Mangosteen contains xanthones with aromatase inhibitory activity.Jul 01, 2008

Click here to read the entire abstract

Pubmed Data : J Nat Prod. 2008 Jul;71(7):1161-6. Epub 2008 Jun 18. PMID: 18558747

Article Published Date : Jul 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Mangosteen

Diseases : Estrogen Dominance

Pharmacological Actions : Anticarcinogenic Agents, Aromatase Inhibitors

Additional Keywords : Xanthones

[+]

Melatonin counteracts the pro-carcinogenic properties of estradiol in breast cancer cells. Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : J Pineal Res. 2009 Aug;47(1):23-31. Epub 2009 Jun 10. PMID: 19522736

Article Published Date : Aug 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Melatonin

Diseases : Breast Cancer, Estrogen Dominance

Pharmacological Actions : BRCA-1 Downregulation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation

[+]

Natural plant compounds may have preventive and therapeutic applications against the growth of breast tumors induced by environmental estrogeDec 01, 1998

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 1998 Dec;106(12):807-12. PMID: 9831541

Article Published Date : Dec 01, 1998

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, Isoflavones

Diseases : Breast Cancer, Estrogen Dominance, Pesticide Toxicity , Xenobiotic Exposures

Pharmacological Actions : Antineoplastic Agents, Antiproliferative

[+]

Phytoestrogens-mediated induction of phase II detoxification enzymes may be responsible for their protective effect against estrogen-induced breast cancer. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Biochem J. 2005 Jan 1;385(Pt 1):279-87. PMID: 15456407

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Biochanin A, Genistein, Resveratrol

Diseases : Breast Cancer, DNA damage, Estrogen Dominance

Pharmacological Actions : Phase II Detoxification Enzyme Inducer

Additional Keywords : Estrogen Receptor Beta, Stilbenes

[+]

Resveratrol and NAC may prevent DNA-estrogen adducts associated with carcinogenesis. Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Future Oncol. 2010 Jan;6(1):75-91. PMID: 20021210

Article Published Date : Jan 01, 2010

Study Type : Review

Additional Links

Substances : NAC (N-acetyl-L-cysteine), Resveratrol, Stilbenes

Diseases : Breast Cancer, Cancers: All, Cancers: Estrogen Responsive, DNA damage, Estrogen Dominance

Pharmacological Actions : Antineoplastic Agents, Antioxidants

[+]

Resveratrol may reduce the pro-coagulant adverse effects associated with high estrogen conditions.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Thromb Res. 2011 Jan;127(1):e1-7. PMID: 20926118

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Contraception, Estrogen Dominance, Hormone Replacement Therapy, Thrombosis

Pharmacological Actions : Anti-thrombotic

[+]

The soy isoflavone daidzein enhances the clearance of estradiol (E2) from the body possibly contributing to its chemopreventive effect.Feb 01, 1999

Click here to read the entire abstract

Pubmed Data : J Gastroenterol. 1999 Feb;34(1):75-82. PMID: 16598814

Article Published Date : Feb 01, 1999

Study Type : In Vitro Study

Additional Links

Substances : Daidzein, Isoflavones

Diseases : Breast Cancer, Endometrial Cancer, Estrogen Dominance

Pharmacological Actions : Chemopreventive, Estradiol 3-glucuronide enhancer

[+]

Unlike tamoxifen and estradiol pomegranate exerts selective estrogen receptor modulator activity without uterotrophic properties.Aug 10, 2011

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2011 Aug 10. Epub 2011 Aug 10. PMID: 21839626

Article Published Date : Aug 10, 2011

Study Type : In Vitro Study

Additional Links

Substances : Pomegranate

Diseases : Estrogen Deficiency, Estrogen Dominance

Pharmacological Actions : Selective estrogen enzyme modulator (SEEM)

Additional Keywords : HRT Alternatives, Superiority of Natural Substances versus Drugs

Problem Substances : 17beta-estradiol, Tamoxifen

Adverse Pharmacological Actions : Uterotrophic

[+]

Vitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells.Aug 01, 2000

Click here to read the entire abstract

Pubmed Data : Clin Cancer Res. 2000 Aug;6(8):3371-9. PMID: 10955825

Article Published Date : Aug 01, 2000

Study Type : In Vitro Study

Additional Links

Substances : Vitamin D

Diseases : Breast Cancer, Estrogen Dominance

Pharmacological Actions : Estrogen Antagonists

Additional Keywords : Estrogen Receptor Positive Breast Cancer

[+]

Yerba mate contains a potent aromatase inhibitor. Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : Eur J Med Chem. 2008 Sep;43(9):1865-77. Epub 2007 Dec 7. PMID: 18192087

Article Published Date : Sep 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Yerba Mate

Diseases : Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

Research Articles 39
Cumulative Knowledge Score 63
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 39 Abstracts with Estrogen Dominance Research

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A very low fat, high fiber diet in healthy premenopausal women can reduce estradiol and estrone levels without affecting ovulation, thereby providing a rationale for the prevention of breast cancer through a very low fat, high fiber diet.Dec 15, 1995

Breast cancer survivors who use estrogenic botanical supplements have lower serum estrogen levels than non users.Sep 01, 2009

Dietary seeweed favorably alters phytoestrogen metabolism with a likely positive change in colonic bacteria in healthy postmenopausal women. May 01, 2009

Estradiol may have proinflammatory effects in older men with coronary artery disease.Dec 01, 2010

Higher estradiol levels are associated with gynecomastia.Nov 02, 1984

Safety: soy food consumption lowers estrogen levels in nipple aspirate fluid and serum. Jul 08, 2011

Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal womenApr 30, 2006

Soy product intake is inversely associated with serum androgen and estrogen concentrations in Japanese men. Jan 01, 2000

Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism.Jun 01, 2010

Brown kelp exhibits anti-estrogenic activity and mildly increases progesterone levels in female rats.Feb 01, 2005

Consumption of bladderwrack results in an increase in the length of the menstrual cycle, and has significant anti-estrogenic and progestagenic effects.Aug 04, 2004

Rosemary leaves enhance the metabolism of endogenous estrogens and decreases their uterotropic effect in mice. Oct 01, 1998

Rye lignan reduces estradiol-induced uterine growth.Aug 01, 2009

Triclosan is an endocrine disruptor which exhibits estrogen disruptive and thyroid suppressive activity in rats.Sep 01, 2010

A wide range of metals have been identified to have estrogenic properties.May 01, 2006

Berry components prevent oxidative damage to DNA caused by estradiol (E2) and copper chloride, in vitro. Sep 01, 2002

Cabbage and brussel sprouts act bifunctionally, like an antiestrogen at low concentrations and an estrogen agonist at high concentrations.Oct 01, 2000

Coffee consumption may reduce colon cancer incidence by increasing the sulfation of estrogen.Oct 01, 2006

Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells.Jan 01, 2011

Damiana contains compounds with anti-aromatase activity. Dec 08, 2008

Estrogen dominance (excess or unopposed estradiol) may contribute to Raynaud's phenomenon. Sep 01, 2007

Euonymus altaus and Scutellaria barbarata have prowerful aromatase inhibiting properties.Aug 01, 2004

Genistein suppresses estradiol-induced uterine leiomyoma cell proliferation.Dec 31, 2004

Indole-3 carbinol is a negative regulator of estrogen. Jul 01, 2003

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.Sep 30, 1998

Ipriflavone accelerates clearance of estradiol (E2) through enhancing the activity of the enzyme estradiol 3-glucuronide. Nov 01, 2004

Licorice contains a compound (liquiritigenin) with aromatase inhibitory action 10 times more potent than the first generation aromatase inhibitor aminoglutethimide (Cytadren). Sep 15, 2008

Lignans and flavonoids act as aromatase inhibitors in human preadipocytes. Aug 01, 1994

Mammalian lignans and the soy isoflavone genistein inhibit breast cancer via down-regulation of estrogen production. Apr 01, 2005

Mangosteen contains xanthones with aromatase inhibitory activity.Jul 01, 2008

Melatonin counteracts the pro-carcinogenic properties of estradiol in breast cancer cells. Aug 01, 2009

Natural plant compounds may have preventive and therapeutic applications against the growth of breast tumors induced by environmental estrogeDec 01, 1998

Phytoestrogens-mediated induction of phase II detoxification enzymes may be responsible for their protective effect against estrogen-induced breast cancer. Jan 01, 2005

Resveratrol and NAC may prevent DNA-estrogen adducts associated with carcinogenesis. Jan 01, 2010

Resveratrol may reduce the pro-coagulant adverse effects associated with high estrogen conditions.Jan 01, 2011

The soy isoflavone daidzein enhances the clearance of estradiol (E2) from the body possibly contributing to its chemopreventive effect.Feb 01, 1999

Unlike tamoxifen and estradiol pomegranate exerts selective estrogen receptor modulator activity without uterotrophic properties.Aug 10, 2011

Vitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells.Aug 01, 2000

Yerba mate contains a potent aromatase inhibitor. Sep 01, 2008

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Estrogen Dominance

View the Evidence:
39 Abstracts with Estrogen Dominance Research