Fatty Liver

Name	AC	CK
Curcumin	27	112
Vitamin D	16	94
Vitamin E	9	83
Probiotics	16	76
Coffee	6	63
Silymarin	7	56
Berberine	19	43
Omega-3 Fatty Acids	10	43
Genistein	7	39
Yoghurt	4	32
Polyunsaturated Fatty Acids (PUFAs)	2	30
Resveratrol	11	30
Taurine	3	28
Vitamin C	6	27
Ginseng (Korean)	5	25
Gynostemma	4	25
Hydroxytyrosol	5	25
Chlorogenic Acid	4	24
DHA (Docosahexaenoic Acid)	4	24
Flaxseed	4	24
Garlic	4	24
Green Tea	10	24
Polyphenols	9	24
Nigella sativa (aka Black Seed)	4	23
Carotenoids	3	22
Artichoke	2	20
Black Currant	5	20
Ginsenosides	11	20
Pantethine	1	20
Tea: Black	1	20
Tea: Green	1	20
Anthocyanins	5	19
Astaxanthin	12	19
Turmeric	6	19
Cryptoxanthin	6	17
Fucoidan	5	17
Licorice	5	17
Hydrogen Water	4	16
Lycopene	9	16
Pomegranate	5	16
Spirulina	4	16
Bilberry	3	15
Blue Honeysuckle	6	14
Cannabinoids	3	14
Coenzyme Q10	3	14
EPA (Eicosapentaenoic Acid)	3	14
Fucoxanthin	4	14
Luteolin	3	14
Sulforaphane	3	14
Prebiotics	3	13
Barberry	2	12
Broccoli	2	12
Cannabis	2	12
Chia	2	12
Chicory	2	12
Fiber	2	12
Hesperidin	2	12
Olive Oil	3	12
Selenium	2	12
Silibinin	7	12
Thymoquinone	2	12
Betulinic acid	5	11
Chocolate	2	11
Flavonoids	6	11
Lutein	2	11
Nuts	2	11
Alpha-Carotene	1	10
Breast Milk	1	10
Calcium	1	10
Chlorella (Algae)	1	10
Cocoa	1	10
Curcuminoids	1	10
Fermented Foods and Beverages	5	10
Hibiscus sabdariffa	1	10
Krill	5	10
Lactobacilius bulgaricus	1	10
Magnesium	1	10
Nuts: All	1	10
Orange	1	10
Piperine	1	10
Raisins	1	10
Streptococcus thermophilus	1	10
Tocotrienols	1	10
Zataria multiflora	1	10
Zeaxanthin	1	10
beta-Carotene	1	10
Blueberry	5	9
Kefir	4	9
Lactobacillus rhamnosus GG	5	9
Naringenin	5	9
Paeoniflorin	5	9
Quercetin	5	9
Lactobacillus paracasei	4	8
Rose	4	8
Chinese Skullcap	2	7
Panax Notoginseng	4	7
Astragaloside	2	6
Babchi	3	6
Beta Sitosterol	3	6
Cannabidiol	3	6
Carnosic Acid	3	6
Cranberry	3	6
EGCG (Epigallocatechin gallate)	3	6
FOS (Fructooligosaccharides)	3	6
Fenugreek	2	6
Fisetin	3	6
Glycyrrhizin	3	6
Grape	3	6
Hawthorn	3	6
Lactobacillus plantarum	3	6
Lemon Balm	3	6
Mangiferin	3	6
Nobiletin	4	6
Oleuropein	3	6
Ursolic Acid	3	6
Benzyl isothiocyanate	3	5
Beta-Caryophyllene	3	5
Black Tea	3	5
Chokeberry	3	5
Fish Oil	3	5
Ginger	3	5
Loquat	3	5
Tomatidine	3	5
Xanthohumol	3	5
Alpha-Lipoic Acid	2	4
Asiatic Acid	2	4
Bitter Melon	2	4
Camel Milk	1	4
Catechin	3	4
Chrysin	2	4
Cinnamon	2	4
Citrulline	2	4
Citrus Peel	2	4
Cordyceps Militaris	2	4
Crocin	2	4
Daidzein	2	4
Diosmin	2	4
Dragon Fruit	2	4
Flaxseed Oil	2	4
Gastrodin	2	4
Gingerol	2	4
Ginkgo biloba	2	4
Ginseng	2	4
Honeysuckle	2	4
Honokiol	2	4
Isoflavones	2	4
Kombucha Tea	2	4
Lactobacillus fermentum	2	4
Milk Thistle	3	4
Mulberry	2	4
Myricetin	2	4
Phytate	1	4
Pine Needle	2	4
Procyanidin B2	2	4
Puerarin	2	4
Raspberry ketone	1	4
Red Sage	2	4
Rosemary	2	4
Rosmarinic acid	2	4
Saffron	2	4
Soy Protein	2	4
Stigmasterol	2	4
Tomato	2	4
Avocado	2	3
Berbamine	2	3
Citrus naringin	2	3
L-Carnitine	2	3
Lotus	2	3
Moringa oleifera	2	3
Royal Jelly	2	3
Strawberry	2	3
Tanshinone IIA	2	3
Tetrahydrocurcumin	2	3
Vitamin E: alpha tocopherol	2	3
Acerola	1	2
Adlay	1	2
Algae	1	2
Allicin	1	2
Aloe Vera	1	2
Alpha Linolenic Acid	1	2
Anise	1	2
Apigenin	1	2
Apple Cider Vinegar	1	2
Apricot	1	2
Ashwagandha	1	2
Bamboo	1	2
Banaba	1	2
Banana	1	2
Barley	1	2
Basil	1	2
Bee Pollen	1	2
Bee Venom	1	2
Bergamot	1	2
Bergamot orange	1	2
Beta-glucan	1	2
Bifidobacterium Lactis	1	2
Bile salts	1	2
Bisdemethoxycurcumin	1	2
Burdock	1	2
Caffeine	1	2
Carnosine	1	2
Cherry: All Varieties	1	2
Choline	1	2
Cocoa Butter	1	2
Codonopsis lanceolata	1	2
D-Limonene	1	2
Diosgenin	1	2
Dong Quai	1	2
Dryobalanops aromatica	1	2
Enterodiol	1	2
Eriodictyol	1	2
Eucalyptus	1	2
Eugenol	1	2
Ferulic acid	1	2
Feverfew	1	2
Formononetin	1	2
Fructose	1	2
Galacto-oligosaccharides	1	2
Garden Cress (Lepidium sativum)	1	2
Garlic: Aged	1	2
Genipin	1	2
Ginseng (American)	1	2
Goji	1	2
Grapefruit	1	2
Green Coffee Bean	1	2
Gymnema Sylvestre	1	2
Hazelnut	1	2
Honeydew (melon)	1	2
Hops	1	2
Hu Zhang (Polygonum cuspidatum)	1	2
Isoliquiritigenin	1	2
Isothiocyanates	1	2
Lactobacillus casei: Shirota	1	2
Lactobacillus probiotics	1	2
Lactobacillus reuteri	1	2
Lignans	1	2
Lime	1	2
Loquat Seeds	1	2
MSM (Methylsulfonylmethane)	1	2
Maitake Mushroom	1	2
Mangosteen	1	2
Medium Chain Triglycerides	1	2
Motherwort	1	2
Mukitake mushroom	1	2
Mung Bean	1	2
Oleanolic acid	1	2
Olive leaf extract	1	2
Onion	1	2
Orange: Mandarin	1	2
Parthenolide	1	2
Patchouli	1	2
Pau D'Arco	1	2
Pectin	1	2
Phenethyl isothiocyanate	1	2
Phyllanthus emblica	1	2
Phyllanthus urinaria	1	2
Pistachio nut	1	2
Pomegranate Peel	1	2
Pomegranate flower	1	2
Poria cocos	1	2
Protein Supplement	1	2
Pterostilbene	1	2
Pumpkin Seeds	1	2
Pycnogenol (Pine Bark)	1	2
Radish	1	2
Raspberry	1	2
Red Cabbage	1	2
Red Yeast Rice	1	2
Reishi Mushroom	1	2
Rooibos	1	2
Rutin	1	2
SAMe (S-adenosylmethionine)	1	2
Salvia miltiorrhiza	1	2
Schisandra	1	2
Seaweed: Brown	1	2
Secoisolariciresinol diglucoside (SDG)	1	2
Sesamin	1	2
Shikonin	1	2
Spinach	1	2
Squash: Butternut	1	2
Star Fruit	1	2
Sweet Potato	1	2
Tangeretin	1	2
Tea	1	2
Urolithin A	1	2
Vaccenic acid	1	2
Virgin Coconut Oil	1	2
Vitamin B-3 (Niacin)	1	2
Vitamin E: Gamma-tocotrienol	1	2
Vitexins	1	2
Whey	1	2
Wogonin	1	2
Xanthones	1	2
Yerba Mate	1	2
Apple Polyphenols	1	1
Arctigenin	1	1
B-Carotene	1	1
Blackberry	1	1
Carnosol	1	1
Crocetin	1	1
Dihydrocurcumin	1	1
Fish	1	1
Lychee	1	1
Mugwort	1	1
Nicotinamide adenine dinucleotide (NADH)	1	1
Punicalagin	1	1
Quinoa	1	1
Red Wine Extract	1	1
S-Adenosylmethionine (SAMe)	1	1
Safflower	1	1
Thistle	1	1
Toona sinensis	1	1
Walnut	1	1
Wormwood	1	1
Yacón	1	1

Name	AC	CK
Fructose	26	92
Tamoxifen	6	52
Bisphenol A	8	50
Sugar Sweetened Beverages	3	50
High Fructose Corn Syrup	16	44
Insulin	6	28
Artificially Sweetened Beverages	1	10
Monosodium Glutamate (MSG)	5	10
Phthalates	1	10
Trans Fatty Acids	4	10
Glyphosate	3	7
Bisphenol S	2	4
Hydrogenated Oil	2	4
Irinotecan	2	3
Aspartame	1	2
Bisphenol F	1	2
Roundup (herbicide)	1	2
Sucralose (aka Splenda)	1	2
Sugary soda	1	2
Aluminum	1	1
Amiodarone	1	1
Methotrexate	1	1
Retinyl palmitate	1	1

Name	AC	CK
Exercise	10	62
Dietary Modification: Mediterranean Diet	5	32
Dietary Modification: Low Carbohydrate/Ketogenic	2	30
Exercise: Aerobic	2	20
Breastfeeding	1	10
Electroacupuncture	1	10
Fasting/Caloric Restriction	1	10
Integrative Medicine	1	10
Lifestyle Changes: Positive	1	10
Dietary Modification: Vegetarian	1	3
Acupuncture	1	2
Dietary Modification: Low Glycemic Diet	1	1
Dietary Modification: Wheat/Gluten Free	1	1

Name	AC	CK	Focus
Western Diet	8	17

[+]

Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Complement Ther Med. 2020 Jan ;48:102283. Epub 2019 Dec 17. PMID: 31987259

Article Published Date : Dec 31, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Curcumin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents, Hypolipidemic

[+]

Effect of green coffee bean extract supplementation on liver function and inflammatory biomarkers.Apr 30, 2021

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Pubmed Data : Complement Ther Clin Pract. 2021 May ;43:101349. Epub 2021 Mar 4. PMID: 33714861

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Pubmed Data : Clin Nutr. 2016 Dec 23. Epub 2016 Dec 23. PMID: 28040302

Article Published Date : Dec 22, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Omega-3 Fatty Acids, Polyunsaturated Fatty Acids (PUFAs)

Diseases : Hepatic Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Silymarin has positive efficacy to reduce transaminases levels in NAFLD patients.Nov 30, 2017

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[+]

A dietary intervention consisting of a Mediterranean diet could delay or slow down the natural progression of NAFL.Jan 22, 2017

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Pubmed Data : Minerva Med. 2018 Dec ;109(6):418-428. Epub 2018 Sep 13. PMID: 30221912

Article Published Date : Nov 30, 2018

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids, Probiotics

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic, Interferon Gamma Reducer, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Berberis extract can be used as a supplementary medication in treating NAFLD.Jan 31, 2015

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Pubmed Data : Hepat Mon. 2015 Feb ;15(2):e25067. Epub 2015 Feb 5. PMID: 25788958

[+]

DHA supplementation improves liver steatosis in children with NAFLD. Oct 31, 2013

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Pubmed Data : Nutr Metab Cardiovasc Dis. 2013 Nov ;23(11):1066-70. Epub 2012 Dec 7. PMID: 23220074

Article Published Date : Oct 31, 2013

Study Type : Human Study

Additional Links

Substances : DHA (Docosahexaenoic Acid)

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

[+]

Diets with a higher intake of nuts may be associated with a decreased risk of NAFLD.Sep 03, 2019

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Pubmed Data : BMJ Open. 2019 Sep 4 ;9(9):e028961. Epub 2019 Sep 4. PMID: 31488477

[+]

Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.Feb 28, 2019

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Pubmed Data : Med Hypotheses. 2019 Mar ;124:40-41. Epub 2019 Feb 4. PMID: 30798914

Article Published Date : Feb 28, 2019

Study Type : Human Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Nonalcoholic fatty liver disease (NAFLD)

Problem Substances : High Fructose Corn Syrup

[+]

Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD.Mar 11, 2021

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Pubmed Data : Mar Drugs. 2021 Mar 12 ;19(3). Epub 2021 Mar 12. PMID: 33809062

Article Published Date : Mar 11, 2021

Study Type : Human Study

Additional Links

Substances : Fucoidan, Fucoxanthin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-6 Downregulation

[+]

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

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Pubmed Data : Adv Biomed Res. 2016 ;5:2. Epub 2016 Jan 27. PMID: 26955623

Pubmed Data : Hepatology. 2010 Jun;51(6):1961-71. PMID: 20301112

Article Published Date : Jun 01, 2010

Study Type : Human Study

Additional Links

Diseases : Fatty Liver

Problem Substances : Fructose, High Fructose Corn Syrup

[+]

Increasing nutritional fiber results in reduced serum ZO levels, reduced liver enzymes and improved hepatic steatosis in patients with NAFLDNov 17, 2018

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Pubmed Data : Nutrients. 2018 Nov 18 ;10(11). Epub 2018 Nov 18. PMID: 30453660

Article Published Date : Nov 17, 2018

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Pubmed Data : J Ginseng Res. 2016 Jul ;40(3):203-10. Epub 2015 Aug 4. PMID: 27616896

Pubmed Data : BMC Med. 2011 Jul 12 ;9:85. Epub 2011 Jul 12. PMID: 21749681

Pharmacological Actions : Hepatoprotective

Additional Keywords : Risk Reduction

[+]

Obese children with small intestinal bacterial overgrowth have an increased risk for developing NAFLD.Oct 08, 2017

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Pubmed Data : J Pediatr Endocrinol Metab. 2017 Oct 9. Epub 2017 Oct 9. PMID: 28988228

Article Published Date : Oct 08, 2017

Study Type : Human Study

Additional Links

Diseases : Dysbiosis, Nonalcoholic fatty liver disease (NAFLD)

Additional Keywords : Increased Risk

[+]

Observations from this study suggest that cannabis use is associated with lower prevalence of NAFLD.Dec 31, 2016

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Pubmed Data : J Pediatr Gastroenterol Nutr. 2016 Oct 13. Epub 2016 Oct 13. PMID: 27753706

Article Published Date : Oct 12, 2016

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Probiotic yogurt fortified with vitamin D can improve glycemic status in non-alcoholic fatty liver disease patients.Dec 31, 2020

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Pubmed Data : AJR Am J Roentgenol. 2003 Jan;180(1):129-34. PMID: 12490491

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Diseases : Fatty Liver

Additional Keywords : Drug: Tamoxifen

Problem Substances : Tamoxifen

Adverse Pharmacological Actions : Hepatotoxic

[+]

Tamoxifen treatment for breast cancer may result in fatty liver.Nov 01, 2000

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Pubmed Data : Oncol Rep. 2000 Nov-Dec;7(6):1299-304. PMID: 11032933

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Pubmed Data : Nutrients. 2017 Mar 13 ;9(3). Epub 2017 Mar 13. PMID: 28335388

Article Published Date : Mar 12, 2017

Study Type : Animal Study

Additional Links

Substances : Astaxanthin, Flaxseed Oil

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD), Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective, Hypolipidemic

[+]

A combination of Red Sage (Salviae Miltiorrhiza), Panax notoginseny and Dyroblanops aromatica may prevent alcoholic fatty liver disease. Dec 01, 2009

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Pubmed Data : Nihon Arukoru Yakubutsu Igakkai Zasshi. 2009 Dec;44(6):636-48. PMID: 20077758

Article Published Date : Dec 01, 2009

Study Type : Animal Study

Additional Links

Substances : Dryobalanops aromatica, Panax Notoginseng, Red Sage

Diseases : Alcoholic Liver Disease, Fatty Liver

[+]

A diet rich in saturated fat to a diet rich in unsaturated fat can attenuate NAFLD and atherosclerosis development.Dec 31, 2014

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Pubmed Data : PLoS One. 2015 ;10(9):e0139196. Epub 2015 Sep 25. PMID: 26405765

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Pumpkin Seeds

Diseases : Atherosclerosis, Dyslipidemias, Inflammation, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

A herbal complex is an effective herbal formulation in the attenuation of obesity and obesity-induced metabolic dysfunction including NAFLD.Jan 07, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nutr Res. 2016 Jan ;36(1):57-64. Epub 2015 Oct 31. PMID: 26773781

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Pubmed Data : Exp Ther Med. 2019 Jul ;18(1):857-866. Epub 2019 Jun 3. PMID: 31281460

Article Published Date : Jun 30, 2019

Study Type : Animal Study

Additional Links

Substances : Garlic

Diseases : Fatty Liver, Insulin Resistance

Pharmacological Actions : Gastrointestinal Agents

[+]

Alcohol extract of North American ginseng reduces fatty liver, dyslipidemia, and other complications of metabolic syndrome. Aug 31, 2017

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Ameliorative effects of Compound K and ginsenoside Rh1 on non-alcoholic fatty liver disease in rats.Jan 19, 2017

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Pubmed Data : Sci Rep. 2017 Jan 20 ;7:41144. Epub 2017 Jan 20. PMID: 28106137

Article Published Date : Jan 19, 2017

Study Type : Animal Study

Additional Links

Substances : Ginsenosides, Panax Notoginseng

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Ginsenosides, Hepatoprotective, Nonalcoholic fatty liver disease (NAFLD), Panax Notoginseng

[+]

An anti-angiogenic compound from lemon balm leaves attenuates a high-fat diet-induced nonalcoholic fatty liver disease.Apr 17, 2017

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Pubmed Data : PLoS One. 2017 ;12(1):e0169685. Epub 2017 Jan 12. PMID: 28081181

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Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:256-267. Epub 2018 Oct 17. PMID: 30340105

Article Published Date : Nov 30, 2018

Study Type : Animal Study

Additional Links

Substances : Asiatic Acid

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, NF-kappaB Inhibitor

[+]

Astaxanthin and vitamin E effectively improved hepatic gene expression.Mar 07, 2017

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Pubmed Data : Int J Mol Sci. 2017 Mar 8 ;18(3). Epub 2017 Mar 8. PMID: 28282876

Bisdemethoxycurcumin may act as a novel and potent therapeutic agent against NAFLD.Dec 31, 2015

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Pubmed Data : PLoS One. 2016 ;11(2):e0147745. Epub 2016 Feb 16. PMID: 26881746

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Bisdemethoxycurcumin, Silymarin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Natural Substance Synergy

[+]

[+]

Bixin attenuates high-fat diet-caused liver steatosis and inflammatory injury.Dec 31, 2020

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Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:6610124. Epub 2021 Feb 2. PMID: 33603948

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Bixin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Nrf2 activation

[+]

Blackcurrant extract prevents dyslipidemia and hepatic steatosis.May 24, 2020

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Pubmed Data : BMC Complement Altern Med. 2013 ;13:264. Epub 2013 Oct 13. PMID: 24119413

Chicory polysaccharides attenuate high-fat diet induced non-alcoholic fatty liver disease.Oct 14, 2018

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Pubmed Data : Int J Biol Macromol. 2018 Oct 15 ;118(Pt A):886-895. Epub 2018 Jun 28. PMID: 29964102

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Pubmed Data : J Nutr Biochem. 2020 May 22 ;83:108426. Epub 2020 May 22. PMID: 32559586

Article Published Date : May 21, 2020

Study Type : Animal Study

Additional Links

Substances : Citrus Peel , Orange: Mandarin

Diseases : Hepatic Steatosis, Inflammation, Liver Damage, Nonalcoholic fatty liver disease (NAFLD), Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation

[+]

Coadministration of epigallocatechin-3-gallate and caffeine in low dose ameliorates obesity and nonalcoholic fatty liver disease in obese rats.Feb 10, 2019

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Pubmed Data : Phytother Res. 2019 Feb 11. Epub 2019 Feb 11. PMID: 30746789

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Pubmed Data : J Nutr Sci. 2019 ;8:e15. Epub 2019 Apr 22. PMID: 31037218

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Coffee

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective

Additional Keywords : Gut-liver axis

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Lipids Health Dis. 2019 Jan 8 ;18(1):11. Epub 2019 Jan 8. PMID: 30621686

Article Published Date : Jan 07, 2019

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Hepatic Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

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Crocus sativus has a protective action against non-alcoholic fatty liver disease in diabetic rats.Apr 30, 2017

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Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:625-632. Epub 2018 Jun 10. PMID: 29898429

Article Published Date : Aug 31, 2018

Study Type : Animal Study

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Substances : Anthocyanins

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

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Diallyl disulfide attenuates non‑alcoholic steatohepatitis.Jul 31, 2019

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Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Effect of green coffee bean extract supplementation on liver function and inflammatory biomarkers.Apr 30, 2021

Effect of Nigella sativa in the treatment of nonalcoholic fatty liver disease/Mar 15, 2021

Med-Diet is a beneficial pharmaconutritional therapy in patients with NAFLD. Jun 18, 2021

Physical activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD.May 03, 2016

Polyunsaturated fatty acids supplementation can improve liver steatosis and liver functions.Dec 22, 2016

Silymarin has positive efficacy to reduce transaminases levels in NAFLD patients.Nov 30, 2017

Studies on coffee and NAFLD suggest that coffee consumption could have a protective role on fibrosis.Mar 29, 2016

The consumption of sugar-sweetened beverages has a dose-dependent effect on the risk of NAFLD.Jun 20, 2019

The systematic review and meta-analysis support that probiotics are superior to placebo in NAFLD patients.Dec 31, 2018

These results found a significantly decreased risk of NAFLD among coffee drinkers and significantly decreased risk of liver fibrosis.Nov 06, 2016

This meta-analysis supports a positive significant association between higher consumption of sugar sweetened beverages and NAFLD.May 13, 2018

Vitamin E significantly improved liver function and histologic changes in patients with NAFLD/NASH.Jun 30, 2015

8 weeks of provision of a diet low in free sugar content compared with usual diet resulted in significant improvement in hepatic steatosis.Jan 21, 2019

A 12-week aerobic exercise program reduces hepatic fat accumulation and insulin resistance in obese, Hispanic adolescents.Jan 31, 2010

A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients. Apr 30, 2015

A dietary intervention consisting of a Mediterranean diet could delay or slow down the natural progression of NAFL.Jan 22, 2017

A higher dietary vitamin C intake might help reduce the risk of non-alcoholic fatty liver disease.Dec 31, 2015

A low-carbohydrate, ketogenic diet improves fatty liver disease. Feb 01, 2007

A nutraceutical formula containing berberine, chlorogenic acid, and tocotrienols was found to improve a large number of metabolic and liver parameters in overweight subjects.Mar 28, 2015

Alternate-day fasting appears to be an effective diet therapy for individuals with NAFLD that can achieve weight loss and improvement of dyslipidaemia.Dec 17, 2019

Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

An improved diet is particularly important for individuals with a high genetic risk for NAFLD.Mar 27, 2018

Antioxidant activity of hydroxytyrosol and vitamin E reduces systemic inflammation in children with paediatric NAFLD.Oct 11, 2020

Artichoke leaf extracts have benefits in the management of NASH.Dec 31, 2015

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.Nov 30, 2018

Berberis extract can be used as a supplementary medication in treating NAFLD.Jan 31, 2015

Calcium plus calcitriol supplementation for 12 weeks may be potentially effective for biochemical parameters in NAFLD patients. Sep 27, 2016

Chia-supplemented diet ameliorates non-alcoholic fatty liver disease and its metabolic abnormalities in humans.May 18, 2020

Chlorella vulgaris supplementation have therapeutic value in patients with non-alcoholic fatty liver disease.Oct 31, 2012

Cocoa polyphenols improve endothelial function via Nox2 down-regulation in NASH patients.Nov 12, 2017

Coffee use is associated with lower levels of fatty liver. Feb 18, 2010

Combined phthalates influence on glucose and lipid metabolism may increase the possibility for NAFLD and insulin resistance development.Dec 05, 2019

Consumption of fruits that are high in antioxidants could represent a useful means to improve the antioxidant status of NAFLD.Jul 13, 2016

Consumption of hibiscus sabdariffa extracts reduced obesity, abdominal fat, serum FFA and improved liver steatosis.Mar 31, 2014

Consumption of Nigella sativa can reduce the inflammatory biomarkers in patients with NAFLD.May 31, 2019

CoQ10 supplement at a dosage of 100 mg could be effective for improving the systemic inflammation and biochemical variables in NAFLD.Jul 08, 2015

Curcumin prevented the development of immunological alterations in NAFLD.Dec 31, 2016

curcumin supplementation can improve serum levels of inflammatory cytokines in subjects with NAFLD.Feb 29, 2020

Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease.Jul 31, 2020

Delta-tocotrienol was safe, and it effectively improved aminotransferase levels and inflammatory and oxidative stress markers in patients with NAFLD.Dec 31, 2017

DHA supplementation improves liver steatosis in children with NAFLD. Oct 31, 2013

Diets with a higher intake of nuts may be associated with a decreased risk of NAFLD.Sep 03, 2019

Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity.Mar 14, 2017

Earlier feeding habits might affect the clinical expression of non-alcoholic fatty liver disease from 3 to 18 years later, with an apparent drug-like preventive effect of breastfeeding.Oct 01, 2009

Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease.Jan 27, 2020

Effect of Korea red ginseng on nonalcoholic fatty liver disease.Feb 28, 2021

Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients.Apr 30, 2019

Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease.Jun 30, 2018

Electroacupuncture and aerobic interval training exercise are potent modalities that improve liver functions in people with Nonalcoholic fatty liver disease.Oct 28, 2019

EPA increases adiponectin secretion in rodent models of obesity and human obese subjects, possibly through the improvement of the inflammatory changes in obese adipose tissue.Sep 01, 2007

Excessive dietary fructose consumption appears to contribute to metabolic syndrome and non-alcholic fatty liver disease. Jun 01, 2008

Exercise overcomes skeletal muscle insulin resistance. Aug 01, 2011

Fatty infiltration of the liver is correlated with amount of abdominal fat.Jul 28, 2011

Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.Jan 28, 2020

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.Feb 28, 2019

Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD.Mar 11, 2021

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

Garlic powder supplementation improved risk factors of NAFLD. May 31, 2020

Genistein can reduce insulin resistance, oxidative and inflammatory indices along with improvement in fat metabolism in patients with NAFLD.May 31, 2017

Genistein inhibits nonalcoholic fatty liver disease.Nov 01, 2007

Green tea extract therapy resulted in significant improvement in metabolic, chemical, inflammatory and radiological parameters of NAFLD patients.Jun 30, 2017

Gynostemma pentaphyllum is an effective adjunct treatment to diet therapy for patients with nonalcoholic fatty liver disease.May 01, 2006

Hesperidin supplementation accompanied with lifestyle modification is superior to lifestyle modification alone in management of NAFLD.Jun 30, 2019

High intake of magnesium may be associated with reduced risks of fatty liver disease and prediabetes.Apr 01, 2018

High levels of urinary BPA were associated with NAFLD in a nationally representative sample of adults in the US.Mar 28, 2019

Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.May 16, 2019

Hijamat resulted in a relative improvement in fatty liver severity and improved HOMA-IR and liver enzymes.Jan 08, 2020

Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease.Apr 10, 2019

Inclusion of dried grapes in diet was beneficial in NAFLD patients with non-significant fibrosis.Nov 08, 2016

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease.Jun 01, 2010

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758 Abstracts with Fatty Liver Research