Fatty Liver

Name	AC	CK
Curcumin	21	77
Vitamin E	6	62
Silymarin	7	56
Coffee	5	53
Probiotics	11	50
Vitamin D	8	40
Omega-3 Fatty Acids	8	39
Genistein	5	36
Polyunsaturated Fatty Acids (PUFAs)	2	30
Taurine	3	28
Resveratrol	8	25
DHA (Docosahexaenoic Acid)	4	24
Polyphenols	8	22
Berberine	10	20
Gynostemma	1	20
Pantethine	1	20
Tea: Black	1	20
Tea: Green	1	20
Yoghurt	2	20
Black Currant	4	18
Anthocyanins	4	17
Green Tea	5	16
Spirulina	4	16
Astaxanthin	8	14
Bilberry	2	14
Blue Honeysuckle	6	14
EPA (Eicosapentaenoic Acid)	3	14
Flaxseed	3	14
Hydroxytyrosol	3	14
Licorice	3	14
Ginseng (Korean)	3	13
Pomegranate	3	13
Barberry	2	12
Broccoli	2	12
Cannabinoids	2	12
Carotenoids	2	12
Coenzyme Q10	2	12
Garlic	2	12
Olive Oil	3	12
Prebiotics	2	12
Sulforaphane	2	12
Vitamin C	2	12
Chocolate	2	11
Artichoke	1	10
Breast Milk	1	10
Calcium	1	10
Cannabis	1	10
Chlorella (Algae)	1	10
Cocoa	1	10
Fiber	1	10
Hibiscus sabdariffa	1	10
Krill	5	10
Lactobacilius bulgaricus	1	10
Magnesium	1	10
Nigella sativa (aka Black Seed)	1	10
Orange	1	10
Raisins	1	10
Streptococcus thermophilus	1	10
Zataria multiflora	1	10
Paeoniflorin	5	9
Kefir	3	8
Rose	4	8
Blueberry	4	7
Naringenin	4	7
Astragaloside	2	6
Cannabidiol	3	6
Carnosic Acid	3	6
Fisetin	3	6
Ginsenosides	3	6
Lycopene	3	6
Oleuropein	3	6
Beta-Caryophyllene	3	5
Chokeberry	3	5
Fish Oil	3	5
Flavonoids	3	5
Lactobacillus rhamnosus GG	3	5
Panax Notoginseng	3	5
Turmeric	3	5
Xanthohumol	3	5
Asiatic Acid	2	4
Beta Sitosterol	2	4
Betulinic acid	2	4
Bitter Melon	2	4
Camel Milk	1	4
Chlorogenic Acid	2	4
Citrulline	2	4
Crocin	2	4
Daidzein	2	4
Dragon Fruit	2	4
EGCG (Epigallocatechin gallate)	2	4
Fenugreek	1	4
Flaxseed Oil	2	4
Fucoidan	2	4
Gastrodin	2	4
Gingerol	2	4
Ginkgo biloba	2	4
Glycyrrhizin	2	4
Grape	2	4
Hawthorn	2	4
Honokiol	2	4
Hydrogen Water	2	4
Isoflavones	2	4
Lactobacillus paracasei	2	4
Mangiferin	2	4
Nobiletin	3	4
Phytate	1	4
Pine Needle	2	4
Procyanidin B2	2	4
Quercetin	2	4
Raspberry ketone	1	4
Red Sage	2	4
Saffron	2	4
Soy Protein	2	4
Stigmasterol	2	4
Ursolic Acid	2	4
Avocado	2	3
Black Tea	2	3
Cryptoxanthin	2	3
Ginger	2	3
Moringa oleifera	2	3
Silibinin	2	3
Tetrahydrocurcumin	2	3
Allicin	1	2
Alpha-Lipoic Acid	1	2
Apricot	1	2
Banaba	1	2
Bergamot orange	1	2
Bile salts	1	2
Bisdemethoxycurcumin	1	2
Caffeine	1	2
Catechin	1	2
Cherry: All Varieties	1	2
Chinese Skullcap	1	2
Cinnamon	1	2
Cocoa Butter	1	2
Codonopsis lanceolata	1	2
Cordyceps Militaris	1	2
Cranberry	1	2
D-Limonene	1	2
Diosgenin	1	2
Diosmin	1	2
Dryobalanops aromatica	1	2
Enterodiol	1	2
Eucalyptus	1	2
FOS (Fructooligosaccharides)	1	2
Fermented Foods and Beverages	1	2
Ferulic acid	1	2
Fructose	1	2
Galacto-oligosaccharides	1	2
Garlic: Aged	1	2
Genipin	1	2
Ginseng	1	2
Ginseng (American)	1	2
Goji	1	2
Gymnema Sylvestre	1	2
Hesperidin	1	2
Honeydew (melon)	1	2
Hops	1	2
Hu Zhang (Polygonum cuspidatum)	1	2
Lactobacillus casei: Shirota	1	2
Lactobacillus plantarum	1	2
Lactobacillus probiotics	1	2
Lignans	1	2
Loquat	1	2
Loquat Seeds	1	2
Luteolin	1	2
MSM (Methylsulfonylmethane)	1	2
Mangosteen	1	2
Medium Chain Triglycerides	1	2
Mukitake mushroom	1	2
Mulberry	1	2
Olive leaf extract	1	2
Onion	1	2
Parthenolide	1	2
Pau D'Arco	1	2
Pectin	1	2
Phyllanthus emblica	1	2
Phyllanthus urinaria	1	2
Pistachio nut	1	2
Pomegranate Peel	1	2
Pomegranate flower	1	2
Protein Supplement	1	2
Puerarin	1	2
Pumpkin Seeds	1	2
Pycnogenol (Pine Bark)	1	2
Red Cabbage	1	2
Red Yeast Rice	1	2
Reishi Mushroom	1	2
Rosemary	1	2
Rutin	1	2
SAMe (S-adenosylmethionine)	1	2
Schisandra	1	2
Seaweed: Brown	1	2
Secoisolariciresinol diglucoside (SDG)	1	2
Selenium	1	2
Sesamin	1	2
Squash: Butternut	1	2
Star Fruit	1	2
Thymoquinone	1	2
Tomato	1	2
Vaccenic acid	1	2
Virgin Coconut Oil	1	2
Vitamin E: Gamma-tocotrienol	1	2
Whey	1	2
Wogonin	1	2
Xanthones	1	2
Yerba Mate	1	2
Arctigenin	1	1
Blackberry	1	1
Dihydrocurcumin	1	1
Fish	1	1
Fucoxanthin	1	1
Lychee	1	1
Milk Thistle	1	1
Mugwort	1	1
Nuts	1	1
Punicalagin	1	1
Red Wine Extract	1	1
Strawberry	1	1
Tanshinone IIA	1	1
Thistle	1	1
Walnut	1	1
Yacón	1	1

Name	AC	CK
Fructose	25	90
Tamoxifen	6	52
High Fructose Corn Syrup	15	43
Bisphenol A	6	38
Sugar Sweetened Beverages	2	30
Insulin	3	14
Monosodium Glutamate (MSG)	5	10
Trans Fatty Acids	4	10
Glyphosate	3	7
Hydrogenated Oil	2	4
Irinotecan	2	3
Bisphenol S	1	2
Roundup (herbicide)	1	2
Sugary soda	1	2
Amiodarone	1	1
Methotrexate	1	1
Retinyl palmitate	1	1

Name	AC	CK
Exercise	7	57
Dietary Modification: Mediterranean Diet	4	31
Dietary Modification: Low Carbohydrate/Ketogenic	1	20
Breastfeeding	1	10
Exercise: Aerobic	1	10
Integrative Medicine	1	10
Lifestyle Changes: Positive	1	10
Acupuncture	1	2
Dietary Modification: Low Glycemic Diet	1	1
Dietary Modification: Wheat/Gluten Free	1	1

Name	AC	CK	Focus
Western Diet	8	17

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective, Hypoglycemic Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

Gamma-tocotrienol supplementation is effective in attenuating NAFLD and fibrosis.Jan 10, 2018

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Pubmed Data : Mol Nutr Food Res. 2018 11 ;62(21):e1800519. Epub 2018 Sep 9. PMID: 30183139

Article Published Date : Jan 10, 2018

Study Type : Animal Study

Additional Links

Substances : Vitamin E: Gamma-tocotrienol

Diseases : Inflammation, Liver Fibrosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

Problem Substances : High Fructose Corn Syrup

[+]

Ganoderma lucidum polysaccharide peptide alleviates hepatoteatosis.Dec 31, 2017

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Pubmed Data : Mol Nutr Food Res. 2019 Oct 1:e1900811. Epub 2019 Oct 1. PMID: 31574193

Article Published Date : Sep 30, 2019

Study Type : Animal Study

Additional Links

Substances : Green Tea

Diseases : Endotoxemia, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, NF-kappaB Inhibitor

[+]

Green tea extract rich in epigallocatechin-3-Gallate prevents fatty liver in mice fed a high-fat diet.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(11):e0141227. Epub 2015 Nov 4. PMID: 26536464

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Fatty Liver, High Fat Diet

Pharmacological Actions : Hepatoprotective

Additional Keywords : Plant Extracts, Risk Reduction

[+]

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Hepatoprotective and anti-obesity effects of Korean blue honeysuckle extracts in high fat diet-fed mice.Dec 30, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Exerc Nutrition Biochem. 2018 Dec 31 ;22(4):39-54. PMID: 30661330

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2018 Jan 17 ;23(1). Epub 2018 Jan 17. PMID: 29342107

Article Published Date : Jan 16, 2018

Study Type : Animal Study

Additional Links

Substances : Honokiol

Diseases : Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

Additional Keywords : Ovariectomy-Induced Changes

[+]

Hydrogen water is the therapeutic agent in electrolyzed-alkaline water and attenuates high fat diet-induced nonalcoholic fatty liver disease.Dec 06, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Can J Physiol Pharmacol. 2014 Oct ;92(10):805-12. Epub 2014 Aug 11. PMID: 25211173

Article Published Date : Sep 30, 2014

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Fatty Liver, High Fat Diet, Metabolic Diseases

Pharmacological Actions : Heme oxygenase-1 up-regulation

[+]

Inhibitory effect of blue honeysuckle extract on high-fat-diet-induced fatty liver in mice.Aug 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anim Nutr. 2018 Sep ;4(3):288-293. Epub 2018 Jun 27. PMID: 30175257

Article Published Date : Aug 31, 2018

Study Type : Animal Study

Additional Links

Substances : Blue Honeysuckle

Diseases : Fatty Liver, High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation

Additional Keywords : Anti-Obesity Agents

[+]

Inositol hexaphosphate inhibits lipogenesis in the liver, indicating that it may help to protect against fatty liverSep 01, 1999

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Pubmed Data : Anticancer Res. 1999 Sep-Oct;19(5A):3695-8. PMID: 10625942

Article Published Date : Sep 01, 1999

Study Type : Animal Study

Additional Links

Substances : Phytate

Diseases : Fatty Liver, Hepatic Steatosis, Liver: Fatty

[+]

Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet.Sep 30, 2018

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Pubmed Data : Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct ;1863(10):1274-1284. Epub 2018 Aug 7. PMID: 30305244

Article Published Date : Sep 30, 2018

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Pubmed Data : J Nutr Biochem. 2017 06 ;44:35-43. Epub 2017 Mar 4. PMID: 28384519

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Kefir

Diseases : Fatty Liver, Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Hepatoprotective, Interleukin-6 Downregulation

Additional Keywords : Anti-Obesity Agents

[+]

Kefir peptides can improve the symptoms of NAFLD.Dec 11, 2016

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Pubmed Data : Nutr Diabetes. 2016 Dec 12 ;6(12):e237. Epub 2016 Dec 12. PMID: 27941940

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Pubmed Data : Biomed Res Int. 2015 ;2015:645984. Epub 2015 Aug 2. PMID: 26301251

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Krill

Diseases : High Fat Diet, Lipid Peroxidation, Mitochondrial Dysfunction , Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Additional Keywords : Microbiota

[+]

L. paracasei Jlus66 has great potential as a probiotic in protecting from NAFLD.Nov 05, 2017

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Pubmed Data : Food Funct. 2017 Nov 6. Epub 2017 Nov 6. PMID: 29106426

Article Published Date : Nov 05, 2017

Study Type : Animal Study

Additional Links

Substances : Lactobacillus paracasei

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Prophylactic Agents

[+]

Lactobaccilus casei Shirota protects from fructose-induced fatty liver in an animal model. Jun 26, 2012

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Pubmed Data : J Nutr Biochem. 2012 Jun 27. Epub 2012 Jun 27. PMID: 22749137

Article Published Date : Jun 26, 2012

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei: Shirota

Diseases : Fructose-Induced Toxicity , Liver Stress: Fructose-Induced, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Problem Substances : Fructose

Adverse Pharmacological Actions : Hepatotoxic, Lipogenesis Up-Regulation

[+]

Lactobacillus fermentum CQPC06 prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis.Oct 20, 2020

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Pubmed Data : Food Funct. 2020 Oct 21 ;11(10):8707-8723. PMID: 32945305

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Pubmed Data : Mol Nutr Food Res. 2017 Aug ;61(8). Epub 2017 Mar 2. PMID: 28116779

Article Published Date : Jul 31, 2017

Study Type : Animal Study

Additional Links

Substances : Nobiletin

Diseases : Dyslipidemias, High Fat Diet, Inflammation, Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Loquat seed inhibits fatty liver, inflammation and fibrosis in the treatment of non-alcoholic fatty liver disease. Feb 01, 2010

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Pubmed Data : J Pharm Pharmacol. 2010 Feb;62(2):241-6. PMID: 20487204

Click here to read the entire abstract

Pubmed Data : Int J Biol Macromol. 2018 Sep 25 ;120(Pt B):1480-1489. Epub 2018 Sep 25. PMID: 30266645

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : World J Gastroenterol. 2016 Dec 14 ;22(46):10180-10188. PMID: 28028366

Article Published Date : Dec 13, 2016

Study Type : Animal Study

Additional Links

Substances : Lycopene

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Antioxidants, Dose Response, Hepatoprotective, lycopene, Nonalcoholic fatty liver disease (NAFLD), Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Lycopene shows therapeutic potential to NAFLD.Aug 04, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Food Funct. 2020 Sep 24. Epub 2020 Sep 24. PMID: 32969440

Article Published Date : Sep 23, 2020

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

[+]

Mate tea reduces high fat diet-induced liver and metabolic disorders in mice.Jan 01, 2019

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Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:1547-1555. Epub 2018 Nov 14. PMID: 30551407

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2017 Jun 22 ;18(7). Epub 2017 Jun 22. PMID: 28640194

Article Published Date : Jun 21, 2017

Click here to read the entire abstract

Pubmed Data : Food Funct. 2019 Mar 20 ;10(3):1465-1477. PMID: 30776032

Article Published Date : Mar 19, 2019

Study Type : Animal Study

Additional Links

Substances : Myricetin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, MicroRNA modulator

[+]

Myricetin modulates macrophage polarization and mitigates liver inflammation and fibrosis in a murine model of nonalcoholic steatohepatitis.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Mol Sci. 2018 Dec 8 ;19(12). Epub 2018 Dec 8. PMID: 30544824

Article Published Date : Dec 07, 2018

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Autophagy Up-regulation, Hepatoprotective

[+]

Oleuropein exhibits hepatoprotective properties in mice fed a high-fat diet.Sep 01, 2010

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Pubmed Data : Biotechnol J. 2010 Sep;5(9):950-60. PMID: 20845385

Click here to read the entire abstract

Pubmed Data : J Nutr Metab. 2012 ;2012:268680. Epub 2011 Sep 12. PMID: 21918718

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Fatty Liver, Hepatic Steatosis

Therapeutic Actions : Exercise

Pharmacological Actions : Hepatoprotective

[+]

Orally administered pycnogenol may serve to prevent NASH-induced liver damage.Sep 30, 2012

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Pubmed Data : Phytother Res. 2012 Oct ;26(10):1572-4. Epub 2012 Feb 1. PMID: 22294490

Article Published Date : Sep 30, 2012

Study Type : Animal Study

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : Hepatic Steatosis, Nonalcoholic fatty liver disease (NAFLD)

[+]

P. anisum fruit extract and essential oil have beneficial effects in the treatment of NAFLD.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Res Med Sci. 2017 ;22:37. Epub 2017 Mar 15. PMID: 28465696

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Anise

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

Additional Keywords : Essential Oils

[+]

P. cocos modulates gut microbiota to improve hyperglycemia and hyperlipidemia.Dec 31, 2018

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Pubmed Data : Chin J Nat Med. 2019 Jan ;17(1):3-14. PMID: 30704621

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Pubmed Data : Phytother Res. 2017 Mar 16. Epub 2017 Mar 16. PMID: 28299850

Article Published Date : Mar 15, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Pine Needle

Diseases : Fatty Liver

Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

Pistachio consumption is able to prevent and to ameliorate obesity-related dysfunctions.Nov 30, 2018

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Pubmed Data : J Sci Food Agric. 2016 Sep 22. Epub 2016 Aug 22. PMID: 27717115

Article Published Date : Sep 21, 2016

Study Type : Animal Study

Additional Links

Substances : Pomegranate

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Prophylactic Agents

Additional Keywords : Risk Reduction

[+]

Pomegranate peel extract might be considered as a potential lead material in the treatment of NAFLD and obesity.Feb 29, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Food Nutr Res. 2020 ;64. Epub 2020 Feb 4. PMID: 32110174

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Sweet Potato

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Apoptotic, Hepatoprotective

[+]

Quercetin could be used for obesity-associated NAFLD via its anti-inflammatory, antioxidant and prebiotic integrative response.Nov 24, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Gastroenterol Hepatol. 2016 Aug ;31(8):1462-9. PMID: 26699443

Article Published Date : Jul 31, 2016

Study Type : Animal Study

Additional Links

Substances : Dragon Fruit

Diseases : High Fat Diet, Insulin Resistance, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Microbiota

[+]

Red pitaya juice may provide protection against liver damage and may reduce the stiffness of the heart.Jun 11, 2014

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Pubmed Data : BMC Complement Altern Med. 2014 Jun 12 ;14:189. Epub 2014 Jun 12. PMID: 24919841

Article Published Date : Jun 11, 2014

Study Type : Animal Study

Additional Links

Substances : Dragon Fruit

Diseases : Cardiovascular Diseases, Fatty Liver, Metabolic Syndrome X, Obesity

Pharmacological Actions : Hepatoprotective

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Red yeast rice has therapeutic potential in treating obesity and hyperlipidemia.Sep 30, 2015

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Pubmed Data : J Med Food. 2015 Oct ;18(10):1095-102. Epub 2015 Jul 1. PMID: 26133037

[+]

Salvianolic acid B can decrease oxidative stress reaction and play a therapeutic role in the treatment of NASH.Dec 06, 2017

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Pubmed Data : Arch Med Res. 2017 Dec 7. Epub 2017 Dec 7. PMID: 29224910

Article Published Date : Dec 06, 2017

Study Type : Animal Study

Additional Links

Substances : Red Sage

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Sasa veitchii extract reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.Dec 31, 2016

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Pubmed Data : Nagoya J Med Sci. 2017 08 ;79(3):279-290. PMID: 28878433

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Bamboo

Diseases : Fatty Liver, Insulin Resistance, Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

Additional Keywords : Anti-Obesity Agents, Plant Extracts

[+]

Saturated fat (trans fatty acids) and fructose play a role in the pathogenesis of nonalcoholic fatty liver disease.Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Annu Rev Pathol. 2010;5:145-71. PMID: 20078219

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Jan 18 ;11(1). Epub 2019 Jan 18. PMID: 30669332

Pubmed Data : Environ Toxicol Pharmacol. 2019 Feb ;66:43-54. Epub 2018 Dec 13. PMID: 30597379

Article Published Date : Feb 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Metab (Lond). 2018 ;15:55. Epub 2018 Aug 6. PMID: 30093912

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Pectin

Diseases : Fatty Liver, Obesity

Pharmacological Actions : Hepatoprotective, Hypolipidemic

Additional Keywords : Risk Reduction

[+]

Taheebo attenuates increase in body weight and fatty liver in mice fed a high-fat diet.Oct 07, 2014

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Pubmed Data : Molecules. 2014 Oct 8 ;19(10):16013-23. Epub 2014 Oct 8. PMID: 25299819

Article Published Date : Oct 07, 2014

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Pubmed Data : Obesity (Silver Spring). 2011 Jul ;19(7):1396-403. Epub 2011 Feb 3. PMID: 21293445

Article Published Date : Jun 30, 2011

Study Type : Animal Study

Additional Links

Substances : Hydrogen Water

Diseases : Diabetes Mellitus: Type 2, Fatty Liver, Obesity, Oxidative Stress

Pharmacological Actions : Fibroblast growth factor 21 upregulation, Hypoglycemic Agents

Additional Keywords : Anti-Obesity Agents

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The present study revealed for the first time that carnosic acid has a protective effect against hepatocyte apoptosis in NAFLD.Dec 31, 2014

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These findings suggest that a green rooibos extract has potential as an anti-steatotic, anti-inflammatory and weight reducing agent in vivo.Jun 30, 2019

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Pubmed Data : Int J Food Sci Nutr. 2020 Nov 18:1-12. Epub 2020 Nov 18. PMID: 33203257

Article Published Date : Nov 17, 2020

Study Type : Animal Study

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Substances : Pomegranate

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Neuroprotective Agents

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These observations demonstrate that β-caryophyllene has a cholesterol-lowering effect on hypercholesterolemic rats.Apr 30, 2018

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Pubmed Data : J Clin Biochem Nutr. 2018 May ;62(3):230-237. Epub 2018 Feb 7. PMID: 29892161

Article Published Date : Apr 30, 2018

Study Type : Animal Study

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Substances : Beta-Caryophyllene

Diseases : Atherosclerosis, Fatty Liver, Hypercholesterolemia

Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic

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These results confirm that the incorporation of chia seed in the diet in postnatal life may provide a viable therapeutic option for preventing/mitigating adverse outcomes induced by an sucrose-rich diet from utero to adulthood.Jan 01, 2017

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Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2017 01 ;116:19-26. Epub 2016 Dec 6. PMID: 28088290

Article Published Date : Jan 01, 2017

Study Type : Animal Study

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Diseases : Dyslipidemias, Fatty Liver, Insulin Resistance

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These results show that chronic consumption of β-glucans can improve glucose control and decrease fatty liver in a model of diabetes with obesity.Oct 01, 2013

These results suggest that cranberry ameliorates high fat diet-induced metabolic disturbances.Dec 31, 2018

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Pubmed Data : Biol Pharm Bull. 2019 ;42(8):1295-1302. PMID: 31366865

Article Published Date : Dec 31, 2018

Study Type : Animal Study

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Substances : Cranberry

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective

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These results suggested that ginsenoside Rb2 alleviated hepatic lipid accumulation by restoring autophagy.May 18, 2017

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Pubmed Data : Nutrients. 2015 Oct 21 ;7(10):8670-84. Epub 2015 Oct 21. PMID: 26506376

Article Published Date : Oct 20, 2015

Study Type : Animal Study

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Substances : Honeysuckle

Diseases : Inflammation, Liver Cirrhosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Phytotherapy, Plant Extracts

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This study revealed a lipid regulation and anti-oxidant insights of gastrodin on NAFLD.Apr 22, 2019

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Turmeric extracts could be used in the prevention or treatment of NAFLD.Dec 31, 2015

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Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:8495953. Epub 2016 May 30. PMID: 27366193

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Turmeric

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

[+]

Ultra-low dose of Roundup herbicide non-alcoholic contributes to fatty liver disease in rats following chronic exposure.Jan 08, 2017

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Pubmed Data : Endocr J. 2017 Jul 28 ;64(7):663-673. Epub 2017 May 23. PMID: 28539530

Article Published Date : Jul 27, 2017

Study Type : Animal Study

Additional Links

Substances : Vitamin D

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Vitexin alleviates non-alcoholic fatty liver disease by activating AMPK in high fat diet fed mice.Oct 28, 2019

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Pubmed Data : Biochem Biophys Res Commun. 2019 Oct 29 ;519(1):106-112. Epub 2019 Aug 29. PMID: 31472955

Article Published Date : Oct 28, 2019

Study Type : Animal Study

Additional Links

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Water extract of Curcuma longa L. ameliorates non-alcoholic fatty liver disease.Oct 20, 2019

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Pubmed Data : Biomed Pharmacother. 2017 May 6 ;91:621-631. Epub 2017 May 6. PMID: 28486193

A review of thirty years of Lactobacillus rhamnosus GG.Feb 28, 2019

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Pubmed Data : J Clin Gastroenterol. 2019 Mar ;53 Suppl 1:S1-S41. PMID: 30741841

Article Published Date : Feb 28, 2019

Study Type : Review

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Allergies, Cardiovascular Diseases, Cystic Fibrosis, Diarrhea, Diarrhea: Antibiotic-Associated, Gastrointestinal Diseases, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD), Respiratory Tract Infections

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Accumulating data shows that curcumin plays a critical role in combating liver fibrogenesis.May 31, 2015

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Pubmed Data : Dig Dis Sci. 2015 Jun ;60(6):1554-64. Epub 2014 Dec 23. PMID: 25532502

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Pubmed Data : J Nutr Biochem. 2020 Aug 12:108478. Epub 2020 Aug 12. PMID: 32801031

Article Published Date : Aug 11, 2020

Study Type : Review

Additional Links

Substances : Catechin , Green Tea

Diseases : Lipopolysaccharide-Induced Toxicity, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

Additional Keywords : Gut-liver axis

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Fisetin ameliorated high-fat and high-sucrose-induced NAFLD.Mar 11, 2019

Fisetin restrains high fat diet-induced hepatic inflammation and lipid deposition.Mar 19, 2019

Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice.Jul 01, 2007

Flaxseed lignan attenuates high-fat diet-induced visceral and liver fat accumulation and induces adiponectin expression in mice.Sep 01, 2008

Flos Lonicera and metformin in combination exerts a synergistic effect on the improvement of hepatosteatosis and insulin sensitivity.Dec 31, 2016

Formononetin alleviates hepatic steatosis by facilitating TFEB-mediated lysosome biogenesis and lipophagy.Jul 24, 2019

Fresh garlic minimised the high-fat-diet-induced fatty liver changes in rats.Sep 30, 2015

Fructo-oligosaccharides and intestinal barrier function in a methionine-choline-deficient mouse model of nonalcoholic steatohepatitis.Dec 31, 2016

Fructose contributes to the development of obesity and fatty live. Mar 16, 2009

Fructose induces adverse changes associated with fatty liver disease in an animal model. Feb 01, 2011

Fructose is used to induce fatty liver disease in a rat model of insulin resistance. Dec 01, 2009

Fructose is used to induce fatty liver disease in a rat model. Jan 01, 2010

Fructose is used to induce fatty liver disease in an animal model and may contribute to endotoxemiea. Dec 01, 2010

Fructose supplementation induced hypertriglyceridemia and hyperleptinemia, hepatic steatosis and necroinflammation, increased the expression of genes related to fatty acid synthesis and decreased fatty acidβ-oxidation activity.Feb 15, 2011

Fucoidan ameliorated the development of high fat diet-induced NAFLD.Oct 31, 2015

Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis.Jul 22, 2020

Fuzhuan tea prevented diet-induced inflammation in the liver, and also altered intestinal function.Feb 17, 2016

Galangin improved non-alcoholic fatty liver Disease in mice by promoting autophagy.Dec 31, 2019

Gamma-tocotrienol supplementation is effective in attenuating NAFLD and fibrosis.Jan 10, 2018

Ganoderma lucidum polysaccharide peptide alleviates hepatoteatosis.Dec 31, 2017

Gastrodin ameliorates oxidative stress and proinflammatory response in nonalcoholic fatty liver disease.Feb 29, 2016

Genipin Reverses high fat diet-induced liver damage.Dec 31, 2017

Geniposide and chlorogenic acid combination ameliorates non-alcoholic steatohepatitis.Dec 31, 2017

Genistein ameliorates non-alcoholic fatty liver disease by targeting the thromboxane A2 pathway.May 30, 2018

Genistein and moderate intensity exercise were effective in reducing the severity of NASH.May 31, 2020

Ginkgolide A may be feasible as a therapeutic agent for NAFLD patients.Mar 31, 2017

Ginseng seed oil ameliorates hepatic lipid accumulation in vitro and in vivo.Sep 30, 2018

Ginsenoside compound K attenuates the development of atherosclerosis.Jul 07, 2016

Ginsenoside Rb1 alleviated high fat diet-induced apoptosis of hepatocytes of mice via PPAR-γ.Dec 31, 2019

Ginsenoside Rg1 can inhibit inflammatory reaction, regulate lipid metabolism, and alleviate liver injury in NAFLD.May 18, 2020

Ginsenoside Rg1 protects against non-alcoholic fatty liver disease.Oct 31, 2018

Glucoraphanin supplementation attenuated weight gain, decreased hepatic steatosis, and improved glucose tolerance and insulin sensitivity.Feb 15, 2017

Glycyrrhizic acid produces a markedly protective effect against non-alcoholic steatohepatitis.Aug 03, 2016

Glycyrrhizic acid protects against non-alcoholic fatty liver disease in mice due to regulation of genes involved in lipid, glucose homeostasis and insulin sensitivity.Jul 05, 2017

Glycyrrhizin alleviates non-alcoholic steatohepatitis.Jun 28, 2018

Glyphosate is metabolized to glyoxylate and reacts with cysteines on liver proteins.Feb 15, 2017

Grape juice concentrate modulates p16 expression in high fat diet-induced liver steatosis.Mar 31, 2012

Green tea extract catechins protect against NF-κB-mediated liver injury in nonalcoholic steatohepatitis.Sep 30, 2019

Green tea extract rich in epigallocatechin-3-Gallate prevents fatty liver in mice fed a high-fat diet.Dec 31, 2014

Green tea has a beneficial effect in a rat model of non-alcoholic fatty liver. May 01, 2009

Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats.Jul 22, 2019

Gymnena sylvestre suppresses weight gain and accumulation of liver lipids.Jun 01, 2001

Gynostemma pentaphylla modulated the gut microbiota and suppressed hepatic miR-34a, which was associated with the amelioration of hepatic steatosis.Dec 31, 2017

Gypenoside UL4-rich Gynostemma pentaphyllum extract exerts a hepatoprotective effect on diet-induced nonalcoholic fatty liver disease.Dec 31, 2017

Hepatoprotective and anti-obesity effects of Korean blue honeysuckle extracts in high fat diet-fed mice.Dec 30, 2018

Hepatoprotective effect of kombucha tea in rodent model of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.May 12, 2019

High carbohydrate diets alone can generate both liver fat and fibrosis.Jan 31, 2017

High dietary protein content has an antisteatotic and antiobesogenic effect in mice.Jun 30, 2017

High Fructose Corn Syrup may promote hepatic steatosis, whereas dietary Monosodium Glutamate (MSG) induces dyslipidemia and markers of insulin resistance.Jan 28, 2010

High fructose feeding induces copper deficiency in rats which may contribute to metabolic syndrome, including hyperlipidemia and fatty liver.Jul 19, 2011

High-fructose corn syrup-55 consumption alters hepatic lipid metabolism and promotes triglyceride accumulation.Sep 29, 2016

Honokiol can attenuate high cholesterol and high fat diet induced non-alcoholic steatohepatitis.Jul 01, 2017

Honokiol improves liver steatosis in ovariectomized mice.Jan 16, 2018

Hydrogen water is the therapeutic agent in electrolyzed-alkaline water and attenuates high fat diet-induced nonalcoholic fatty liver disease.Dec 06, 2018

Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.Aug 31, 2012

Hydroxytyrosol may reduce the liver alterations induced in high fat diet-fed mice.Apr 18, 2017

In vitro and in vivo data indicate that the hop constituent xanthohumol affects several critical pathophysiological steps during the development and course of chronic liver disease.Dec 31, 2014

Increased HO-1 expression, along with suppressed oxidative stress as well as reduced hepatic fat accumulation and fibrotic changes, contribute to the beneficial effects of curcumin.Sep 30, 2014

Inhibitory effect of blue honeysuckle extract on high-fat-diet-induced fatty liver in mice.Aug 31, 2018

Inositol hexaphosphate inhibits lipogenesis in the liver, indicating that it may help to protect against fatty liverSep 01, 1999

Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet.Sep 30, 2018

Intestinal dysbios is a possible causative factor in alcohol-incuded endotoxemia and alcoholic fatty liver in rats. Oct 01, 2009

Iso-alpha acids from hops inhibit hepatic steatosis, inflammation, and fibrosis.Nov 30, 2018

Kefir alleviates obesity and hepatic steatosis in high-fat diet-fed mice by modulation of gut microbiota and mycobiota.Dec 31, 2016

Kefir peptides can improve the symptoms of NAFLD.Dec 11, 2016

Korean red ginseng may be a safe alternative therapy to prevent NASH progression.Oct 08, 2018

Krill could significantly improve dyslipidemia, fatty liver, and glucose metabolism in C57BL/6J mice.Nov 20, 2017

Krill oil counteracts the negative effects of a high-fat diet on mitochondrial energetic metabolism.Dec 31, 2014

Krill oil is superior to fish oil at reducing liver triglyceride and cholesterol levels. Feb 25, 2011

Krill powder improves lipid status in liver glucose and lipid metabolism, and improves inflammation, in transgenic mice fed a high-fat diet.Apr 24, 2012

L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet.Oct 09, 2019

L. caerulea L. berry polyphenols potentially attenuated inflammation in NAFLD through modulation of gut microbiota.Dec 04, 2018

View the Evidence:
674 Abstracts with Fatty Liver Research