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25 Substances Researched for Fever
NameACCKFocus
Homeopathic Medicine: All213Locked
Breast Milk 110Locked
Japanese Herbal Formula: Mao-to110Locked
Yoghurt110Locked
Butterfly Pea24Locked
Curcumin24Locked
Lotus 23Locked
Mango 13Locked
Amla Fruit12Locked
Andrographis12Locked
Bauhinia purpurea12Locked
Coconut12Locked
Coconut Oil12Locked
Guduchi 12Locked
Holy Basil12Locked
Mululuza12Locked
NAC (N-acetyl-L-cysteine)12Locked
Puerarin12Locked
Ruta Graveolens12Locked
Solanum nigrum (black nightshade)12Locked
Avocado11Locked
Carpolobia lutea11Locked
Honeysuckle11Locked
Neem11Locked
Saffron11Locked
8 Problem Substances Researched for Fever
NameACCKFocus
Paracetamol230Locked
Tylenol230Locked
Acetaminophen110Locked
Diclofenac110Locked
Ibuprofen110Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)110Locked
Perfluorinated compounds110Locked
Aspirin 12Locked
4 Therapeutic Actions Researched for Fever
NameACCKFocus
Breastfeeding110Locked
Cupping110Locked
Tepid Sponging110Locked
Fasting/Caloric Restriction11Locked
6 Problematic Actions Researched for Fever
NameACCKFocus
Vaccination: All330Locked
Electroconvulsive Therapy110Locked
Vaccination: Influenza110Locked
Vaccination: Measles110Locked
Vaccination: Mumps-Measles-Rubella (MMR)110Locked
Vaccination: Varicella (Chicken pox)110Locked

View the Evidence:
38 Abstracts with Fever Research

[+]

Trial evidence that paracetamol has a superior antipyretic effect than placebo is inconclusive.Jan 01, 2002

Pubmed Data : Cochrane Database Syst Rev. 2002(2):CD003676. PMID: 12076499
Article Published Date : Jan 01, 2002
Study Type : Meta Analysis
Additional Links
Diseases : Fever
Problem Substances : Paracetamol, Tylenol
[+]

Antipyretic agents are ineffective for the prevention of recurrences of febrile seizures and for the lowering of body temperature in patients with a febrile episode that leads to a recurrent febrile seizure.Sep 01, 2009

Pubmed Data : Arch Pediatr Adolesc Med. 2009 Sep ;163(9):799-804. PMID: 19736332
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : Febrile Seizures, Fever
Problem Substances : Diclofenac, Ibuprofen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Paracetamol, Tylenol
[+]

Breastfeeding is associated with a decreased incidence of fever after immunizations.Jun 01, 2010

Pubmed Data : Pediatrics. 2010 Jun;125(6):e1448-52. Epub 2010 May 17. PMID: 20478932
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Breast Milk
Diseases : Fever, Vaccine-induced Toxicity
Therapeutic Actions : Breastfeeding
Anti Therapeutic Actions : Vaccination: All
[+]

Daily supplementation of children's diet with yogurt containing probiotics significantly reduced days of fever and improved social and school functioning.May 31, 2015

Pubmed Data : J Pediatr. 2015 Jun ;166(6):1475-81.e1-3. Epub 2015 Apr 1. PMID: 25841539
Article Published Date : May 31, 2015
Study Type : Human Study
Additional Links
Substances : Yoghurt
Diseases : Fever
Pharmacological Actions : Prophylactic Agents
Additional Keywords : Risk Reduction
[+]

Fever after electroconvulsive therapy is a common side effect in 8.8% of patients treated, with fever sessions having longer seizure duration, postictal delirium, and higher white blood cell count.Dec 31, 2021

Pubmed Data : Neuropsychobiology. 2022 ;81(1):19-27. Epub 2021 Jul 7. PMID: 34233323
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Fever
Anti Therapeutic Actions : Electroconvulsive Therapy
[+]

Mao-to, a Japanese herbal medicine, is more effective than Oseltamivir in controlling fever due to type A influenza infection in children. Feb 01, 2007

Pubmed Data : Phytomedicine. 2007 Feb;14(2-3):96-101. Epub 2006 Dec 1. PMID: 17141491
Article Published Date : Feb 01, 2007
Study Type : Human Study
Additional Links
Substances : Japanese Herbal Formula: Mao-to
Diseases : Fever, Influenza A
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Of children with leukemia vaccinated with the varicella vaccine, 56% developed vaccine-induced chickenpox and 80% developed fever.Jan 11, 2016

Pubmed Data : Pediatr Infect Dis J. 2016 11 ;35(11):e348-e352. PMID: 27753768
Article Published Date : Jan 11, 2016
Study Type : Human Study
Additional Links
Diseases : Fever, Varicella
Anti Therapeutic Actions : Vaccination: All, Vaccination: Varicella (Chicken pox)
[+]

Tepid sponging helps to reduce fever in children.Jan 01, 2003

Pubmed Data : Cochrane Database Syst Rev. 2003(2):CD004264. PMID: 12804512
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Diseases : Fever
Therapeutic Actions : Tepid Sponging
[+]

The most common serious adverse events reported with the trivalent influenza vaccine was fevers and seizures.Jul 09, 2009

Pubmed Data : Vaccine. 2009 Jul 9 ;27(32):4278-83. Epub 2009 May 28. PMID: 19450636
Article Published Date : Jul 09, 2009
Study Type : Human Study
Additional Links
Diseases : Fever, Seizures
Anti Therapeutic Actions : Vaccination: Influenza
[+]

There is an increased risk of fever following the measles vaccine.Jan 15, 2017

Pubmed Data : J Infect Dis. 2017 04 15 ;215(8):1188-1196. PMID: 28077730
Article Published Date : Jan 15, 2017
Study Type : Human Study
Additional Links
Diseases : Fever
Anti Therapeutic Actions : Vaccination: All, Vaccination: Measles, Vaccination: Mumps-Measles-Rubella (MMR)
[+]

This study found a positive association between prenatal exposure to PFOS and PFOA and the prevalence of fever.Oct 31, 2016

Pubmed Data : Environ Int. 2016 Nov ;96:58-64. Epub 2016 Sep 5. PMID: 27608427
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Fever, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Perfluorinated compounds
Adverse Pharmacological Actions : Immunotoxic
[+]

This study found that cupping effectively improved fever in 96.12% of individuals with upper respiratory infection.Jun 01, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Chin Med. 2002 Jun ;22(2):124-5. PMID: 12125487
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Diseases : Fever, Upper Respiratory Infections
Therapeutic Actions : Cupping
[+]

Viburcol was an effective alternative to acetaminophen treatment and significantly better tolerated.Dec 31, 2004

Pubmed Data : Explore (NY). 2005 Jan ;1(1):33-9. PMID: 16781498
Article Published Date : Dec 31, 2004
Study Type : Human Study
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Cramp, Febrile Infections, Fever
Pharmacological Actions : Anti-pyretic
Additional Keywords : Homeopathic Vs. Conventional Treatment, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs
Problem Substances : Acetaminophen
[+]

Phytochemical, antioxidant, antipyretic and anti-inflammatory activities of aqueous-methanolic leaf extract of Mangifera indica.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2023 ;15(7):4533-4543. Epub 2023 Jul 15. PMID: 37560231
Article Published Date : Dec 31, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mango
Diseases : Fever, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Anti-pyretic , Antioxidants
[+]

Treatment of fever of unknown origin by homeopathyMar 14, 1994

Pubmed Data : Harefuah. 1994 Mar 15 ;126(6):317-20, 368, 367. PMID: 8194786
Article Published Date : Mar 14, 1994
Study Type : Human: Case Report
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Fever
Pharmacological Actions : Anti-pyretic
[+]

Amla has potent anti-pyretic and analgesic activity.Nov 01, 2004

Pubmed Data : J Ethnopharmacol. 2004 Nov;95(1):83-5. PMID: 15374611
Article Published Date : Nov 01, 2004
Study Type : Animal Study
Additional Links
Substances : Amla Fruit
Diseases : Fever
Pharmacological Actions : Analgesics: Non-Narcotic, Anti-pyretic
[+]

Analgesic and antipyretic activities of ethyl acetate fraction tablet of Andrographis paniculata.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:8848797. Epub 2021 Mar 8. PMID: 33747115
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Andrographis
Diseases : Chronic Pain, Fever
Pharmacological Actions : Analgesics, Anti-pyretic
[+]

Anti-inflammatory, analgesic and antipyretic properties of Clitoria ternatea root.May 31, 2003

Pubmed Data : Fitoterapia. 2003 Jun ;74(4):345-9. PMID: 12781804
Article Published Date : May 31, 2003
Study Type : Animal Study
Additional Links
Substances : Butterfly Pea
Diseases : Fever, Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anti-inflammatory, anti-nociceptive and antipyretic activity of young and old leaves of Vernonia amygdalina.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Mar ;111:1187-1203. Epub 2019 Jan 15. PMID: 30841432
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Mululuza
Diseases : Fever, Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic , Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Aspirin may be contraindicated in children with febrile illness because it causes gastrointestinal bleeding.Sep 01, 1989

Pubmed Data : Taiwan Yi Xue Hui Za Zhi. 1989 Sep;88(9):869-73. PMID: 2621427
Article Published Date : Sep 01, 1989
Study Type : Animal Study
Additional Links
Diseases : Cold and Flu: Infants & Children , Febrile Seizures, Fever
Problem Substances : Aspirin
[+]

Bauhinia purpurea possesses pain-killing, anti-inflammatory and fever-reducing properties.Jan 01, 2007

Pubmed Data : Med Princ Pract. 2007;16(6):443-9. PMID: 17917444
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Bauhinia purpurea
Diseases : Fever, Inflammation, Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic
Additional Keywords : Plant Extracts
[+]

Black nightshade (S. nigrum) has antinociceptive, anti-inflammatory and antipyretic effects in animal models. Nov 01, 2006

Pubmed Data : Yakugaku Zasshi. 2006 Nov;126(11):1171-8. PMID: 17077618
Article Published Date : Nov 01, 2006
Study Type : Animal Study
Additional Links
Substances : Solanum nigrum (black nightshade)
Diseases : Fever, Inflammation, Pain
Pharmacological Actions : Anti-Inflammatory Agents, Anti-pyretic , Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Coconut oil has anti-inflammatory, analgesic and antipyretic activities.Feb 01, 2010

Pubmed Data : Pharm Biol. 2010 Feb;48(2):151-7. PMID: 20645831
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Coconut, Coconut Oil
Diseases : Fever, Inflammation, Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic
[+]

Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits.Sep 28, 2008

Pubmed Data : Eur J Pharmacol. 2008 Sep 28;593(1-3):105-11. Epub 2008 Jul 15. PMID: 18664365
Article Published Date : Sep 28, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Fever, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-pyretic , Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Evaluation of antipyretic potential of Clitoria ternatea L. extract.Dec 31, 2003

Pubmed Data : Phytomedicine. 2004 ;11(4):323-6. PMID: 15185845
Article Published Date : Dec 31, 2003
Study Type : Animal Study
Additional Links
Substances : Butterfly Pea
Diseases : Fever
Pharmacological Actions : Anti-pyretic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Lotus has antipyretic properties.Jun 01, 2000

Pubmed Data : Phytother Res. 2000 Jun;14(4):272-4. PMID: 10861971
Article Published Date : Jun 01, 2000
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Fever
Pharmacological Actions : Anti-pyretic
[+]

Pretreatment with NAC and curcumin inhibit staphylococcal enteroxin A-induced fever in rabbits.Jul 01, 2004

Pubmed Data : Mol Cell Biochem. 2004 Jul;262(1-2):177-85. PMID: 15532722
Article Published Date : Jul 01, 2004
Study Type : Animal Study
Additional Links
Substances : Curcumin, NAC (N-acetyl-L-cysteine)
Diseases : Fever, Staphylococcal Infections
Pharmacological Actions : Anti-pyretic , NF-kappaB Inhibitor
[+]

Puerarin exerts antipyretic effect on lipopolysaccharide-induced fever.May 06, 2012

Pubmed Data : J Ethnopharmacol. 2012 May 7 ;141(1):322-30. Epub 2012 Feb 28. PMID: 22401764
Article Published Date : May 06, 2012
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Fever, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Anti-pyretic , Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy
[+]

R. graveolens has antinociceptive, anti-inflammatory and antipyretic activities.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Afr J Tradit Complement Altern Med. 2014 ;11(3):173-81. Epub 2014 Apr 3. PMID: 25371580
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ruta Graveolens
Diseases : Fever, Inflammation, Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic , Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Root extracts holy basil exhibits anti-inflammatory, analgesic and anti-pyretic activity.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2015 May ;11(Suppl 1):S217-24. PMID: 26109769
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Holy Basil
Diseases : Fever, Inflammation, Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic
Additional Keywords : Dose Response, Plant Extracts
[+]

T. cordifolia extract has strong analgesic, anti-inflammatory and anti-pyretic effects.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Clin Exp Med. 2015 Nov-Dec;24(6):957-64. PMID: 26771966
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Guduchi
Diseases : Fever, Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

P. americana had analgesic, anti-inflammatory, antipyretic, and antihyperglycemic properties.Apr 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2021 May ;24(5):641-649. PMID: 34249266
Article Published Date : Apr 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Avocado
Diseases : Fever, Inflammation
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic , Hypoglycemic Agents
[+]

An updated review on Nelumbo nucifera: chemical composition, nutritional value and pharmacological activities.Apr 30, 2024

Pubmed Data : Chem Biodivers. 2024 May ;21(5):e202301493. Epub 2024 Apr 17. PMID: 38327030
Article Published Date : Apr 30, 2024
Study Type : Review
Additional Links
Substances : Lotus
Diseases : Fever, Hyperglycemia, Hyperlipidemia, Obesity, Oxidative Stress
Pharmacological Actions : Anti-pyretic , Antioxidants, Antiviral Agents, Hepatoprotective, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Anti-Obesity Agents, Plant Extracts
[+]

Fasting during fevers due to infection may significantly reduce the risk of developing autoimmune diseases. Jan 11, 2011

Pubmed Data : Am J Gastroenterol. 2011 Jan 11. Epub 2011 Jan 11. PMID: 11703168
Article Published Date : Jan 11, 2011
Study Type : Commentary
Additional Links
Diseases : Fever
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Identification of compounds with antipyretic effects and anti-endotoxin activity in different species of Lonicera japonica using spectrum-effect correlation.Jun 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2021 Jul ;22(1):665. Epub 2021 Apr 22. PMID: 33986830
Article Published Date : Jun 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : Honeysuckle
Diseases : Fever
Pharmacological Actions : Anti-pyretic
[+]

Review on pharmacological and toxicologyical effects of oleum azadirachti oil.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Biomed. 2013 Oct ;3(10):834-40. Epub 2013 Sep 4. PMID: 24075352
Article Published Date : Sep 30, 2013
Study Type : Review
Additional Links
Substances : Neem
Diseases : Asthma, Cardiovascular Diseases, Chickenpox, Colic, Conjunctivitis, Dysmenorrhea, Fever, Gastric Ulcer, Gout, Headache, Malaria, Muscle Soreness, Psoriasis, Rheumatism, Scabies
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Anti-Ulcer Agents, Antimicrobial, Antiviral Agents, Contraceptive Agents, Insect Repellents
Additional Keywords : Plant Oils
[+]

The aim of this work is to collate all available published scientific reports in the literature on Carpolobia.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Rev. 2015 Jul-Dec;9(18):132-9. PMID: 26392711
Article Published Date : Jun 30, 2015
Study Type : Review
Additional Links
Substances : Carpolobia lutea
Diseases : Aspergillosis, Bacillus subtilis infections, Birth: Labor & Delivery, Candida Albicans, Diarrhea, Escherichia coli Infections, Fever, Hyperlipidemia, Leishmaniasis, Obesity, Pseudomonas aeruginosa, Rheumatism, Staphylococcus aureus infection, Sterility, Venereal Diseases: Bacterial
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Anti-pyretic , Antidiarrheals, Antimicrobial, Gastroprotective, Hypolipidemic, Immunomodulatory, Leishmanicidal
Additional Keywords : Anti-Obesity Agents, Natural Substances Versus Drugs, Plant Extracts
[+]

This review highlights the findings regarding antiinflammatory, antioxidant, and immunomodulatory effects of C. sativus and its constituents.Apr 20, 2016

Pubmed Data : Phytother Res. 2016 Apr 21. Epub 2016 Apr 21. PMID: 27098287
Article Published Date : Apr 20, 2016
Study Type : Review
Additional Links
Substances : Saffron
Diseases : Asthma, Bronchitis, Common Cold, Coronary Artery Disease, Fever, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory

Copyright: saiyood / 123RF Stock Photo

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