Fluorosis

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2 Substances Researched for Fluorosis

Name	AC	CK	Focus
Tamarind	1	10
Moringa oleifera	1	2

5 Problem Substances Researched for Fluorosis

Name	AC	CK
Fluoride	5	61
Infant Formula	2	30
Public Drinking Water	1	10
Sodium Fluoride	1	10
Sugary soda	1	10

Research Articles 6
Cumulative Knowledge Score 9
Overall Research Rating GOOD

View the Evidence:
17 Abstracts with Fluorosis Research

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Exposure to high levels of fluoride may adversely influence children's intelligence development.Dec 01, 2008

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Pubmed Data : Zhongguo Dang Dai Er Ke Za Zhi. 2008 Dec;10(6):723-5. PMID: 19102839

Article Published Date : Dec 01, 2008

Study Type : Meta Analysis

Additional Links

Diseases : Childhood Cognitive Disorders, Cognitive Decline/Dysfunction, Fluoride Toxicity , Fluorosis, Intelligence Quotient (IQ): Low/Impaired, Prenatal Nutrition: Learning/Intelligence of Offspring

Problem Substances : Fluoride

Adverse Pharmacological Actions : Neurotoxic

[+]

Infant formula consumption may be associated with an increased risk of developing at least some detectable level of enamel fluorosis.Jan 01, 2009

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Pubmed Data : Evid Based Dent. 2009;10(3):73. PMID: 19820737

Article Published Date : Jan 01, 2009

Study Type : Meta Analysis

Additional Links

Diseases : Fluoride Toxicity , Fluorosis

Problem Substances : Fluoride, Infant Formula

[+]

An intervention with safe drinking water for 5 years in intervention group-mitigated clinical and subclinical symptoms of fluorosis.Feb 01, 2018

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Pubmed Data : Environ Monit Assess. 2018 Feb 2 ;190(3):110. Epub 2018 Feb 2. PMID: 29396763

Article Published Date : Feb 01, 2018

Study Type : Human Study

Additional Links

Substances : Water

Diseases : Fluoride Toxicity , Fluorosis

Problem Substances : Sodium Fluoride

[+]

Dental fluorosis results from fluoride intake by different sources. Jul 01, 2009

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Pubmed Data : Gac Med Mex. 2009 Jul-Aug;145(4):263-7. PMID: 20073427

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Diseases : Fluorosis

Problem Substances : Fluoride, Sodium Fluoride, Sugary soda

[+]

High prevalence of dental fluorosis among schoolchildren in three villages in Sri Lanka.Jan 25, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ceylon Med J. 2017 12 26 ;62(4):218-221. PMID: 29390597

Article Published Date : Jan 25, 2017

Study Type : Human Study

Additional Links

Diseases : Fluoride Toxicity , Fluorosis

Problem Substances : Sodium Fluoride

[+]

Infants fully formula-fed on formulae prepared with optimally fluoridated water (0.7-1.0 mg/L) have a high probability of exceeding the upper limit for fluoride and are at increased risk of dental fluorosis.Jun 02, 2010

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Pubmed Data : J Public Health Dent. 2010 Jun 2. Epub 2010 Jun 2. PMID: 20545827

Article Published Date : Jun 02, 2010

Study Type : Human Study

Additional Links

Diseases : Fluoride Toxicity , Fluorosis

Problem Substances : Fluoride, Infant Formula, Public Drinking Water

[+]

Long-term high intake of fluoride can cause skeletal fluorosis in patients with diabetes insipidus.Jul 24, 2017

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Pubmed Data : Zhongguo Gu Shang. 2017 Jul 25 ;30(7):651-655. PMID: 29424157

Article Published Date : Jul 24, 2017

Study Type : Human Study

Additional Links

Diseases : Diabetes Insipidus, Fluorosis

Additional Keywords : Risk Factors

[+]

Reversal of fluorosis in children with ascorbic acid, calcium and vitamin D3.Sep 30, 1996

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Pubmed Data : Acta Paediatr Jpn. 1996 Oct ;38(5):513-9. PMID: 8942013

Article Published Date : Sep 30, 1996

Study Type : Human Study

Additional Links

Substances : Calcium, Vitamin C, Vitamin D

Diseases : Fluorosis

Pharmacological Actions : Detoxifier

Problem Substances : Sodium Fluoride

[+]

Selenium alleviates apoptosis induced by fluoride through improving the expression of HSP70 and reduces oxidative stress.Apr 07, 2020

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Pubmed Data : Eur J Pharmacol. 2020 Apr 8 ;878:173098. Epub 2020 Apr 8. PMID: 32275908

Article Published Date : Apr 07, 2020

Study Type : Human Study

Additional Links

Substances : Selenium

Diseases : Fluorosis

Pharmacological Actions : Antioxidants, Heat Shock Protein Inducer

[+]

Tamarind intake is likely to help in delaying progression of fluorosis by enhancing urinary excretion of fluoride.Jan 01, 2002

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Pubmed Data : Eur J Clin Nutr. 2002 Jan;56(1):82-5. PMID: 11840184

Article Published Date : Jan 01, 2002

Study Type : Human Study

Additional Links

Substances : Tamarind

Diseases : Fluoride Toxicity , Fluorosis

[+]

Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Bioinformation. 2022 ;18(1):14-18. Epub 2022 Jan 31. PMID: 35815197

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Moringa oleifera

Diseases : Fluorosis

Problem Substances : Sodium Fluoride

[+]

Exposure to high-fluoride resulted in lower body weight and exercise capacity in mice.Feb 15, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2018 Feb 16 ;8(1):3211. Epub 2018 Feb 16. PMID: 29453343

Article Published Date : Feb 15, 2018

Study Type : Animal Study

Additional Links

Diseases : Fluoride Toxicity , Fluorosis

Problem Substances : Sodium Fluoride

[+]

Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.Jan 10, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FEBS Open Bio. 2020 11 ;10(11):2404-2416. Epub 2020 Oct 21. PMID: 33010109

Article Published Date : Jan 10, 2020

Study Type : Animal Study

Additional Links

Substances : Gastrodin

Diseases : Fluorosis

Pharmacological Actions : Antioxidants, Osteoprotective

Problem Substances : Fluoride

[+]

Lycopene significantly combated sodium fluoride induced ameloblasts apoptosis and dental fluorosis.Nov 17, 2016

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Pubmed Data : Chem Biol Interact. 2016 Nov 18 ;261:27-34. Epub 2016 Nov 18. PMID: 27871895

Article Published Date : Nov 17, 2016

Study Type : Animal Study

Additional Links

Substances : Lycopene

Diseases : Fluoride Toxicity , Fluorosis

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Superoxide Dismutase Up-regulation

Problem Substances : Sodium Fluoride

[+]

Neuroprotective effect by naringin against fluorosis-induced neurodegeneration.Jun 06, 2023

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Pubmed Data : Neuroreport. 2023 Jun 7 ;34(9):449-456. Epub 2023 Apr 28. PMID: 37161984

Article Published Date : Jun 06, 2023

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Fluorosis

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Fluoride

[+]

Supplementation of dried M. oleifera fruit powder to fluorosis affected calves resulted in significant reduction in plasma fluoride level.Oct 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Vet World. 2015 Nov ;8(11):1364-9. Epub 2015 Nov 28. PMID: 27047044

Article Published Date : Oct 31, 2015

Study Type : Animal Study

Additional Links

Substances : Moringa oleifera

Diseases : Fluoride Toxicity , Fluorosis

[+]

Fluoride induces apoptosis in H9c2 cardiomyocytes.Apr 30, 2017

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Pubmed Data : Chemosphere. 2017 May 1 ;182:159-165. Epub 2017 May 1. PMID: 28494360

Article Published Date : Apr 30, 2017

Study Type : In Vitro Study

Additional Links

Diseases : Fluorosis

Problem Substances : Sodium Fluoride

Adverse Pharmacological Actions : Cardiotoxic

Fluorosis Related Articles

Fluoride Exposure May Contribute to Degenerative Eye Diseases

Written by GreenMedInfo Research Group

Yet another study adds to the growing body of evidence of fluoride toxicity, shedding light on how it potentially contributes to degenerative eye diseases. Findings like this once again put into question the need for fluoride as a protective agent against tooth decay and peel more layers of the substance's toxic and disease-inducing effects

Open Letter to Nutritionists About the Fluoride Deception

Written by Karen Spencer

Fluoride is not a nutrient of any kind - essential, non-essential or micronutrient. Consumption does not provide any dental benefit, and there is no such thing as a fluoride deficiency

Dispensing with Fluoride

Written by Orthomolecular News Service

Evidence-based medicine requires evidence before medicating. Fluoridation of water is not evidence-based. It has not been tested in well-controlled studies. Fluoridation of public water is a default medication, since you have to deliberately avoid it if you do not want to take it.

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Focus Your Research

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View the Evidence: 17 Abstracts with Fluorosis Research

Limited to Members Only

Currently Available Sorting Options

Exposure to high levels of fluoride may adversely influence children's intelligence development.Dec 01, 2008

Infant formula consumption may be associated with an increased risk of developing at least some detectable level of enamel fluorosis.Jan 01, 2009

An intervention with safe drinking water for 5 years in intervention group-mitigated clinical and subclinical symptoms of fluorosis.Feb 01, 2018

Dental fluorosis results from fluoride intake by different sources. Jul 01, 2009

High prevalence of dental fluorosis among schoolchildren in three villages in Sri Lanka.Jan 25, 2017

Infants fully formula-fed on formulae prepared with optimally fluoridated water (0.7-1.0 mg/L) have a high probability of exceeding the upper limit for fluoride and are at increased risk of dental fluorosis.Jun 02, 2010

Long-term high intake of fluoride can cause skeletal fluorosis in patients with diabetes insipidus.Jul 24, 2017

Reversal of fluorosis in children with ascorbic acid, calcium and vitamin D3.Sep 30, 1996

Selenium alleviates apoptosis induced by fluoride through improving the expression of HSP70 and reduces oxidative stress.Apr 07, 2020

Tamarind intake is likely to help in delaying progression of fluorosis by enhancing urinary excretion of fluoride.Jan 01, 2002

Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats.Dec 31, 2021

Exposure to high-fluoride resulted in lower body weight and exercise capacity in mice.Feb 15, 2018

Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.Jan 10, 2020

Lycopene significantly combated sodium fluoride induced ameloblasts apoptosis and dental fluorosis.Nov 17, 2016

Neuroprotective effect by naringin against fluorosis-induced neurodegeneration.Jun 06, 2023

Supplementation of dried M. oleifera fruit powder to fluorosis affected calves resulted in significant reduction in plasma fluoride level.Oct 31, 2015

Fluoride induces apoptosis in H9c2 cardiomyocytes.Apr 30, 2017

Fluorosis Related Articles

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Fluorosis

View the Evidence:
17 Abstracts with Fluorosis Research