Gallbladder Cancer

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30 Substances Researched for Gallbladder Cancer
NameACCKFocus
Vegetables: All 330Locked
Fruit: All220Locked
Flavonoids314Locked
Polyphenols212Locked
Beans: All 110Locked
Fish110Locked
Green Tea110Locked
Tea: Black110Locked
Magnolol15Locked
Traditional Chinese Medicine: Mylabris34Locked
Artemisinin23Locked
Ginsenosides23Locked
Homeopathic Medicine: All13Locked
Ursolic Acid23Locked
Betulinic acid12Locked
Genistein22Locked
Shikonin12Locked
Arctigenin11Locked
Emodin11Locked
Gallic Acid11Locked
Ganoderic acid11Locked
Hesperidin11Locked
Isoliquiritigenin11Locked
Oridonin11Locked
Piperlongumine 11Locked
Poria cocos11Locked
Pterostilbene11Locked
Resveratrol11Locked
Salvia miltiorrhiza11Locked
Sea buckthorn11Locked
2 Problem Substances Researched for Gallbladder Cancer
NameACCKFocus
Artificially Sweetened Beverages110Locked
Sugar Sweetened Beverages110Locked
1 Therapeutic Actions Researched for Gallbladder Cancer
NameACCKFocus
Fasting/Caloric Restriction110Locked
Related Topics

Gallbladder Cancer is a Sub of the following Topic

View the Evidence:
38 Abstracts with Gallbladder Cancer Research

[+]

Fasting-induced RNF152 resensitizes gallbladder cancer cells to gemcitabine by inhibiting mTORC1-mediated glycolysis.May 16, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : iScience. 2024 May 17 ;27(5):109659. Epub 2024 Apr 8. PMID: 38706841
Article Published Date : May 16, 2024
Study Type : Human Study
Additional Links
Diseases : Gallbladder Cancer
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Gemcitabine
[+]

High consumption of sweetened beverages may increase the risk of biliary tract cancer and gallbladder cancer.Sep 30, 2016

Pubmed Data : J Natl Cancer Inst. 2016 Oct ;108(10). Epub 2016 Jun 8. PMID: 27281756
Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Diseases : Cholangiocarcinoma, Gallbladder Cancer
Additional Keywords : Increased Risk
Problem Substances : Artificially Sweetened Beverages, Sugar Sweetened Beverages
[+]

High inake of fried food and constipation are associated with increased risk of bile duct and gallbladder cancer. The consumption of boiled beans and fish may reduce the risk.Jun 01, 2005

Pubmed Data : J Epidemiol. 2005 Jun;15 Suppl 2:S150-6. PMID: 16127227
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Substances : Beans: All , Fish
Diseases : Constipation, Gallbladder Cancer
Additional Keywords : Diseases that are Linked
[+]

Increased fruit and vegetable consumption may decrease a risk of extrahepatic bile duct cancer.Oct 30, 2016

Pubmed Data : Int J Cancer. 2016 Oct 31. Epub 2016 Aug 31. PMID: 27798952
Article Published Date : Oct 30, 2016
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Cholangiocarcinoma, Gallbladder Cancer
Additional Keywords : Risk Reduction
[+]

Tea consumption reduces the risk of biliary tract and gallbladder diseases.Nov 01, 2005

Pubmed Data : Zhonghua Zhong Liu Za Zhi. 2005 Nov;27(11):667-71. PMID: 16438888
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Substances : Flavonoids, Green Tea, Polyphenols, Tea: Black
Diseases : Bile Duct Cancer, Gallbladder Cancer
Pharmacological Actions : Chemopreventive
[+]

The consumption of fruits and vegetables has a protective effect against the development of bladder cancer.Aug 01, 2002

Pubmed Data : Eur J Cancer Prev. 2002 Aug;11(4):365-8. PMID: 12195163
Article Published Date : Aug 01, 2002
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Gallbladder Cancer
Pharmacological Actions : Chemopreventive
[+]

The risk of gallbladder cancer is inversely related to the level of vegetable consumption. Apr 01, 2006

Pubmed Data : Eur J Cancer Prev. 2006 Apr;15(2):134-7. PMID: 16523010
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Vegetables: All
Diseases : Gallbladder Cancer
[+]

Magnolol induced cell cycle arrest and promoted apoptosis in gallbladder carcinoma cells by regulating the p53 signaling pathway.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Sci. 2015 Oct ;106(10):1341-50. PMID: 26250568
Article Published Date : Sep 30, 2015
Study Type : Human In Vitro
Additional Links
Substances : Magnolol
Diseases : Gallbladder Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest, Cyclin D1 Down-Regulation, P21 Activation, Tumor Suppressor Protein p53 Upregulation
[+]

A homeopathic approach to treat patients with advanced gallbladder, periampullary, and liver carcinomas.Jan 31, 2012

Pubmed Data : J Altern Complement Med. 2012 Feb ;18(2):180-6. PMID: 22339106
Article Published Date : Jan 31, 2012
Study Type : Human: Case Report
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Gallbladder Cancer, Liver Cancer
[+]

Oroxylin A exerts its antitumor effects in human gallbladder cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2020 ;43(10):1511-1518. PMID: 32999161
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Gallbladder Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
[+]

Antitumor effect of ginsenoside Rg3 on gallbladder cancer.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Nov ;16(5):5687-5696. Epub 2018 Aug 20. PMID: 30344724
Article Published Date : Oct 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Artemisinin may be suitable for the treatment of gallbladder cancer.Mar 29, 2016

Pubmed Data : Mol Med Rep. 2016 Mar 30. Epub 2016 Mar 30. PMID: 27035431
Article Published Date : Mar 29, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Betulinic acid induces apoptosis of gallbladder cancer cells via repressing SCD1.Jan 07, 2020

Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2020 Jan 8. Epub 2020 Jan 8. PMID: 31915810
Article Published Date : Jan 07, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Norcantharidin, a compound found within the traditional Chinese medicine Mylabris, has an anti-angiogenic activity in human gallbladder cancer cells.Mar 14, 2006

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2006 Mar 14;86(10):693-9. PMID: 16681930
Article Published Date : Mar 14, 2006
Study Type : Animal Study
Additional Links
Substances : Traditional Chinese Medicine: Mylabris
Diseases : Gallbladder Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Angiogenic, Apoptotic, Vascular Endothelial Growth Factor A Inhibitor
Additional Keywords : Drug: 5-flourouracil
[+]

Shikonin induces apoptosis and G0/G1 phase arrest of gallbladder cancer cells.Nov 30, 2017

Pubmed Data : Oncol Rep. 2017 Dec ;38(6):3473-3480. Epub 2017 Oct 17. PMID: 29039581
Article Published Date : Nov 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Dose Response
[+]

Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Med Biol Res. 2018 Mar 1 ;51(4):e6891. Epub 2018 Mar 1. PMID: 29513793
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Polyphenols
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Antiproliferative, Apoptotic, Cell cycle arrest, Gallbladder Cancer, POLYPHENOLS
[+]

Ursolic acid exhibits significant anti-tumor effects by suppressing cell proliferation, promoting apoptosis in gallbladder cancer cells. Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2014 ;14(1):96. Epub 2014 Oct 29. PMID: 25383044
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation, Cell cycle arrest
Additional Keywords : Dose Response
[+]

20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2015 ;9:3969-87. Epub 2015 Aug 10. PMID: 26309394
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Gallbladder Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

A compound from the traditional Chinese medicine inhibits the growth of human gallbladder cells.Feb 01, 2007

Pubmed Data : Hepatobiliary Pancreat Dis Int. 2007 Feb;6(1):72-80. PMID: 17287171
Article Published Date : Feb 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Traditional Chinese Medicine: Mylabris
Diseases : Gallbladder Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway.Apr 30, 2017

Pubmed Data : Tumour Biol. 2017 May ;39(5):1010428317698359. PMID: 28459363
Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Epidermal growth factor receptor (EGFR) inhibitor
[+]

Artemisinin inhibits proliferation of gallbladder cancer cell lines.Feb 29, 2016

Pubmed Data : Zhonghua Wai Ke Za Zhi. 2016 Mar 1 ;54(3):222-7. PMID: 26932893
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Artemisinin
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Dihydrotanshinone I inhibits gallbladder cancer growth.Jun 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2024 Jul ;129:155661. Epub 2024 Apr 21. PMID: 38677269
Article Published Date : Jun 30, 2024
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Emodin enhances sensitivity of gallbladder cancer cells to chemotherapy.Apr 15, 2010

Pubmed Data : Biochem Pharmacol. 2010 Apr 15;79(8):1134-40. Epub 2009 Dec 11. PMID: 20005210
Article Published Date : Apr 15, 2010
Study Type : In Vitro Study
Additional Links
Substances : Emodin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Gallbladder Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemosensitizer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Gallic acid loaded PEO-core/zein-shell nanofibers for chemopreventive action on gallbladder cancer cells.Jun 30, 2018

Pubmed Data : Eur J Pharm Sci. 2018 Jul 1 ;119:49-61. Epub 2018 Apr 6. PMID: 29630938
Article Published Date : Jun 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Gallbladder Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Ganoderic acid a potentiates cisplatin's cytotoxicity on gallbladder cancer cells by promoting DNA damage and inhibiting cell stemness.Apr 20, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Surg Oncol. 2025 Apr 21 ;23(1):148. Epub 2025 Apr 21. PMID: 40259397
Article Published Date : Apr 20, 2025
Study Type : In Vitro Study
Additional Links
Substances : Ganoderic acid
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Gallbladder Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Genistein suppresses the proliferative activity in Src-activated human gallbladder carcinoma cells.Jul 23, 2020

Pubmed Data : Nutr Cancer. 2020 Jul 24:1-9. Epub 2020 Jul 24. PMID: 32705888
Article Published Date : Jul 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest, P21 Activation, Tumor Suppressor Protein p53 Upregulation
[+]

Hesperidin can be considered as a potential anticancerous compound for the treatment of gall bladder carcinoma.Sep 27, 2018

Pubmed Data : Nutr Cancer. 2018 Sep 28:1-12. Epub 2018 Sep 28. PMID: 30265812
Article Published Date : Sep 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells.Sep 19, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med J (Engl). 2023 Sep 20 ;136(18):2210-2220. Epub 2023 Jul 24. PMID: 37488674
Article Published Date : Sep 19, 2023
Study Type : In Vitro Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Gallbladder Cancer
Pharmacological Actions : Apoptotic
[+]

Isorhamnetin Inhibits human gallbladder cancer cell proliferation and metastasis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:628621. Epub 2021 Feb 17. PMID: 33679411
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Sea buckthorn
Diseases : Gallbladder Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

Long-term exposure to genistein inhibits the proliferation of gallbladder cancer.Apr 29, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Bull (Beijing). 2022 Apr 30 ;67(8):813-824. Epub 2022 Jan 17. PMID: 36546234
Article Published Date : Apr 29, 2022
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative
[+]

Norcantharidin, a compound found within the traditional Chinese medicine Mylabris, inhibits the proliferation and invasion of human gallbladder cancer cells.Apr 28, 2005

Pubmed Data : World J Gastroenterol. 2005 Apr 28;11(16):2431-7. PMID: 15832413
Article Published Date : Apr 28, 2005
Study Type : In Vitro Study
Additional Links
Substances : Traditional Chinese Medicine: Mylabris
Diseases : Cancer Metastasis, Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Oridonin inhibits hypoxia-induced epithelial-mesenchymal transition and cell migration in gallbladder cancer.Jan 09, 2019

Pubmed Data : Anticancer Drugs. 2019 10 ;30(9):925-932. PMID: 31517732
Article Published Date : Jan 09, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Gallbladder Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Pachymic acid inhibits tumorigenesis in gallbladder carcinoma cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2015 ;8(10):17781-8. Epub 2015 Oct 15. PMID: 26770369
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Poria cocos
Diseases : Gallbladder Cancer
Pharmacological Actions : Chemopreventive
[+]

Piperlongumine induces autophagy in biliary cancer cells via reactive oxygen species-activated Erk signaling pathway.Aug 22, 2019

Pubmed Data : Int J Mol Med. 2019 Aug 23. Epub 2019 Aug 23. PMID: 31485612
Article Published Date : Aug 22, 2019
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Cholangiocarcinoma, Gallbladder Cancer
Pharmacological Actions : Autophagy Up-regulation, Chemotherapeutic
[+]

Pterostilbene inhibits gallbladder cancer progression by suppressing the PI3K/Akt pathway.Feb 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Feb 23 ;11(1):4391. Epub 2021 Feb 23. PMID: 33623100
Article Published Date : Feb 22, 2021
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Resveratrol suppresses gallbladder cancer cells.Jun 01, 2005

Pubmed Data : Zhong Yao Cai. 2005 Jun;28(6):489-91. PMID: 16209266
Article Published Date : Jun 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Gallbladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Stilbenes
[+]

Sinensetin flavone has the potential to be developed as a candidate treatment against gallbladder adenocarcinoma.Feb 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J BUON. 2020 Mar-Apr;25(2):1251-1256. PMID: 32521933
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Gallbladder Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Ursolic acid induces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2019 Aug ;18(2):1467-1474. Epub 2019 May 27. PMID: 31423212
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Gallbladder Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic

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