Gout

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52 Substances Researched for Gout
NameACCKFocus
Cherry: All Varieties321Locked
Flavonoids313Locked
Berberine110Locked
Fruit: All110Locked
Vegetables: All 110Locked
Vitamin D110Locked
Cinnamon35Locked
Chrysanthemum Indicum24Locked
Grape Seed Extract24Locked
Ashwagandha23Locked
Apigenin12Locked
Arnica12Locked
Bee Propolis12Locked
Bifidobacterium Longum 12Locked
Bitter Apple12Locked
Burdock12Locked
Chrysin12Locked
Cinnamon Cassia12Locked
EGCG (Epigallocatechin gallate)12Locked
Eucalyptus12Locked
Fiber12Locked
Ginger12Locked
Hesperidin12Locked
Hops12Locked
Oleuropein12Locked
Olive leaf extract12Locked
Rutin12Locked
Silver (nanoparticles)12Locked
Sulforaphane12Locked
Triphala12Locked
Urolithin A 12Locked
Caffeic acid phenethyl ester11Locked
Catechin 11Locked
Chicory11Locked
Coffee11Locked
Curcumin11Locked
Garlic11Locked
Guava11Locked
Hu Zhang (Polygonum cuspidatum)11Locked
Luteolin11Locked
Neem11Locked
Noni11Locked
Plantago asiatica11Locked
Procyanidin B2 11Locked
Puerarin11Locked
Pycnogenol (Pine Bark)11Locked
Quercetin11Locked
Silibinin11Locked
Theaflavins11Locked
Thymol11Locked
Vitamin C21Locked
Yellow Dock11Locked
11 Problem Substances Researched for Gout
NameACCKFocus
Fructose453Locked
Meat240Locked
Seafood240Locked
Sugar Sweetened Beverages221Locked
Alcohol Consumption120Locked
Diuretic: Loop120Locked
High Fructose Corn Syrup120Locked
Sugary soda120Locked
Thiazide120Locked
Soy110Locked
Colchicine11Locked
2 Therapeutic Actions Researched for Gout
NameACCKFocus
Dietary Modification: Vegetarian110Locked
Electroacupuncture12Locked

View the Evidence:
63 Abstracts with Gout Research

[+]

Fructose consumption was associated with an increased risk of developing gout.Oct 02, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ Open. 2016 Oct 3 ;6(10):e013191. Epub 2016 Oct 3. PMID: 27697882
Article Published Date : Oct 02, 2016
Study Type : Meta Analysis, Review
Additional Links
Diseases : Fructose-Induced Toxicity , Gout, Hyperuricemia
Additional Keywords : Increased Risk
Problem Substances : Fructose
[+]

Higher levels of meat and seafood consumption are associated with higher serum levels of uric acid.Jan 01, 2005

Pubmed Data : Arthritis Rheum. 2005 Jan;52(1):283-9. PMID: 15641075
Article Published Date : Jan 01, 2005
Study Type : Meta Analysis
Additional Links
Diseases : Gout, Hyperuricemia
Problem Substances : Meat, Seafood
[+]

Meat intake, alcohol consumption, seafood intake, sugar sweetened soft drinks, use of loop diuretics and thiazide and consumption of foods high in fructose are associated with an increased risk of gout. Mar 01, 2011

Pubmed Data : Curr Opin Rheumatol. 2011 Mar;23(2):192-202. PMID: 21285714
Article Published Date : Mar 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Gout
Problem Substances : Alcohol Consumption, Diuretic: Loop, Fructose, High Fructose Corn Syrup, Meat, Seafood, Sugary soda, Thiazide
[+]

Sugar sweetened beverage consumption was significantly associated with increased risk of gout and hyperuricemia in adult population.Oct 01, 2018

Pubmed Data : Crit Rev Food Sci Nutr. 2018 Oct 2:1-10. Epub 2018 Oct 2. PMID: 30277800
Article Published Date : Oct 01, 2018
Study Type : Meta Analysis, Review
Additional Links
Diseases : Gout, Hyperuricemia
Additional Keywords : Increased Risk
Problem Substances : Sugar Sweetened Beverages
[+]

Bing sweet cherries lowers plasma urate in healthy women, indicating its potential value in the treatment of gout.Jun 01, 2003

Pubmed Data : J Nutr. 2003 Jun;133(6):1826-9. PMID: 12771324
Article Published Date : Jun 01, 2003
Study Type : Human Study
Additional Links
Substances : Cherry: All Varieties
Diseases : Gout, Inflammation
[+]

Cherry consumption decreases risk of recurrent gout attacks.Nov 30, 2012

Pubmed Data : Arthritis Rheum. 2012 Dec ;64(12):4004-11. PMID: 23023818
Article Published Date : Nov 30, 2012
Study Type : Human Study
Additional Links
Substances : Cherry: All Varieties
Diseases : Gout
[+]

Effect of berberine on activation of TLR4-NFκB signaling pathway and NLRP3 inflammasome in patients with gout.Sep 19, 2022

Pubmed Data : Chin J Integr Med. 2022 Sep 20. Epub 2022 Sep 20. PMID: 36125615
Article Published Date : Sep 19, 2022
Study Type : Human Study
Additional Links
Substances : Berberine
Diseases : Gout, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Fructose is used to induce hyperuricacidemia in an experimental model.Apr 30, 1982

Pubmed Data : Boll Soc Ital Biol Sper. 1982 Apr 30;58(8):491-6. PMID: 7093059
Article Published Date : Apr 30, 1982
Study Type : Human Study
Additional Links
Diseases : Gout, Hyperuricemia
Problem Substances : Fructose
[+]

Lower vitamin D levels are associated with depression in patients with gout.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2019 ;15:227-231. Epub 2019 Jan 14. PMID: 30679908
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Depression, Gout, Vitamin D Deficiency
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Risk Factors
[+]

Pycnogenol may be of value in treatment of MSU crystal-induced arthritis through its anti-inflammatory and anti-nitrosative activities.Feb 14, 2012

Pubmed Data : Free Radic Biol Med. 2012 Feb 15 ;52(4):765-74. Epub 2011 Dec 13. PMID: 22198264
Article Published Date : Feb 14, 2012
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
[+]

Soy milk may increase serum urate levels contraindicating it for gout. Sep 01, 2010

Pubmed Data : Ann Rheum Dis. 2010 Sep;69(9):1677-82. Epub 2010 May 14. PMID: 20472590
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Diseases : Gout
Problem Substances : Soy
[+]

Taiwanese vegetarian diet is associated with lower risk of gout.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Nutr. 2020 03 ;39(3):837-844. Epub 2019 Mar 27. PMID: 30955983
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Gout
Therapeutic Actions : Dietary Modification: Vegetarian
Additional Keywords : Risk Reduction
[+]

This study found the peak incidence of acute gout seems to be in the fall with its peak in the month of November.Aug 08, 2015

Pubmed Data : Clin Rheumatol. 2015 Aug 9. Epub 2015 Aug 9. PMID: 26255189
Article Published Date : Aug 08, 2015
Study Type : Human Study
Additional Links
Diseases : Gout
Additional Keywords : Increased Risk
[+]

Ultra processed food consumption was found to be associated with a higher risk of gout.Jan 03, 2024

Pubmed Data : Rheumatology (Oxford). 2024 Jan 4 ;63(1):165-173. PMID: 37129545
Article Published Date : Jan 03, 2024
Study Type : Human Study
Additional Links
Diseases : Gout
Additional Keywords : Ultra-Processed Food
[+]

Fructose contributes to the elevation of uric acid levels. Dec 01, 1987

Pubmed Data : Quad Sclavo Diagn. 1987 Dec;23(4):441-6. PMID: 3509875
Article Published Date : Dec 01, 1987
Study Type : Human: Case Report
Additional Links
Diseases : Gout, Hyperuricemia
Problem Substances : Fructose
[+]

6-Shogaol, a compound found within ginger, exerts a strong anti-inflammatory activity against urate crystal-induced inflammation in mice. Sep 01, 2010

Pubmed Data : Methods Find Exp Clin Pharmacol. 2010 Sep;32(7):467-73. PMID: 19819286
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Gout, Hyperuricemia
[+]

A mixture of Chrysanthemum Indicum flower and Cinnamomum Cassia bark extracts improves hyperuricemia.Sep 27, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Sep 28 ;10(10). Epub 2018 Sep 28. PMID: 30274153
Article Published Date : Sep 27, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chrysanthemum Indicum, Cinnamon Cassia
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Enzyme Inhibitors, Uricosuric Agents, Xanthine oxidase inhibitor
Additional Keywords : Plant Extracts
[+]

Antihyperuricemic effect of urolithin A in cultured hepatocytes and model mice.Nov 03, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Nov 4 ;25(21). Epub 2020 Nov 4. PMID: 33158257
Article Published Date : Nov 03, 2020
Study Type : Animal Study
Additional Links
Substances : Urolithin A
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Uricosuric Agents
[+]

Arctium minus crude extract presents antinociceptive effect in a mice acute gout attack model.Aug 10, 2017

Pubmed Data : Inflammopharmacology. 2017 Aug 11. Epub 2017 Aug 11. PMID: 28801728
Article Published Date : Aug 10, 2017
Study Type : Animal Study
Additional Links
Substances : Burdock
Diseases : Allodynia, Gout
Pharmacological Actions : Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Ashwaganda reverses the symptoms of gouty arthritis in an experimental model with rats.Dec 15, 2006

Pubmed Data : Chem Biol Interact. 2006 Dec 15;164(3):174-80. Epub 2006 Nov 7. PMID: 17084827
Article Published Date : Dec 15, 2006
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Arthritis, Gout
[+]

Chrysanthemum indicum and Cinnamomum cassia mixture may have potential as a treatment for hyperuricemia and gout.Dec 31, 2016

Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:9764843. Epub 2017 Jul 9. PMID: 28769989
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum, Cinnamon
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Uricosuric Agents
Additional Keywords : Natural Substance Synergy
[+]

Chrysin exhibits potent anti-hyperuricemic and anti-inflammatory effects that may yield new adjuvant treatments for gout.Apr 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Apr 6 ;10(4). Epub 2021 Apr 6. PMID: 33917369
Article Published Date : Apr 05, 2021
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Uricosuric Agents
[+]

Cinnamon (cassia) extract has significant effect on serum and liver urate levels.Feb 20, 2006

Pubmed Data : J Ethnopharmacol. 2006 Feb 20;103(3):357-65. Epub 2005 Sep 22. PMID: 16182482
Article Published Date : Feb 20, 2006
Study Type : Animal Study
Additional Links
Substances : Cinnamon
Diseases : Gout
[+]

Comparative antioxidant and anti-gout activities of Citrullus colocynthis loaded fruit silver nanoparticles with its ethanolic extract.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Med Biotechnol. 2022 ;14(4):303-309. PMID: 36504570
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Bitter Apple, Silver (nanoparticles)
Diseases : Gout
Pharmacological Actions : Antioxidants
[+]

EGCG exerts anti-inflammatory effect against monosodium urate induced acute gout attack.May 27, 2016

Pubmed Data : Mol Nutr Food Res. 2016 May 28. Epub 2016 May 28. PMID: 27234527
Article Published Date : May 27, 2016
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Electroacupuncture can be used for relieving acute gout arthritis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:2598975. Epub 2018 Mar 19. PMID: 29743920
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Arthritis, Gout
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Analgesics
[+]

Eucalyptol alleviates inflammation and pain responses in a mouse model of gout arthritis.Dec 26, 2019

Pubmed Data : Br J Pharmacol. 2019 Dec 27. Epub 2019 Dec 27. PMID: 31883118
Article Published Date : Dec 26, 2019
Study Type : Animal Study
Additional Links
Substances : Eucalyptus
Diseases : Arthritis, Gout
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
[+]

Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression.Jan 03, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2017 04 4 ;14(1):74. Epub 2017 Apr 4. PMID: 28376889
Article Published Date : Jan 03, 2017
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Gout, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Proanthocyanidins
[+]

Grapeseed procyanidins lower serum uric acid levels, indicating its usefulness for the treatment of gout.May 01, 2004

Pubmed Data : Basic Clin Pharmacol Toxicol. 2004 May;94(5):232-7. PMID: 15125693
Article Published Date : May 01, 2004
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Gout, Hyperuricemia
[+]

Hesperidin methylchalcone suppresses experimental gout arthritis in mice.Jun 26, 2018

Pubmed Data : J Agric Food Chem. 2018 Jun 27 ;66(25):6269-6280. Epub 2018 Jun 13. PMID: 29852732
Article Published Date : Jun 26, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Gout, Oxidative Stress
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Olive leaf extract has xanthine-oxidase inhibiting activity which confirms its traditional use for gout. May 14, 2011

Pubmed Data : Phytomedicine. 2011 May 15 ;18(7):561-6. Epub 2010 Dec 8. PMID: 21144719
Article Published Date : May 14, 2011
Study Type : Animal Study
Additional Links
Substances : Apigenin, Oleuropein, Olive leaf extract
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Enzyme Inhibitors, Xanthine oxidase inhibitor
Additional Keywords : Drug: Allopurinol, Plant Extracts, Science Confirms Tradition
[+]

Oral Bifidobacterium longum treatment reduced the inflammatory response in an experimental murine model of gout.Nov 30, 2015

Pubmed Data : Benef Microbes. 2015 Dec ;6(6):799-806. Epub 2015 Aug 31. PMID: 26322542
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Bifidobacterium Longum
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Rutin ameliorates gout via reducing XOD activity, inhibiting ROS production and NLRP3 inflammasome activation in quail.Jan 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2023 Feb ;158:114175. Epub 2022 Dec 30. PMID: 36587556
Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Gout, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Sulforaphane inhibits multiple inflammasomes through a novel mechanism and contributes to our understanding of the beneficial effects of sulforaphane.Aug 11, 2015

Pubmed Data : J Leukoc Biol. 2015 Aug 12. Epub 2015 Aug 12. PMID: 26269198
Article Published Date : Aug 11, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Gout, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Taiwanese green propolis might be useful for ameliorating gouty inflammation via inhibition of the NLRP3 inflammasome.Mar 31, 2019

Pubmed Data : J Cell Physiol. 2019 Apr ;234(4):4081-4094. Epub 2018 Oct 28. PMID: 30370562
Article Published Date : Mar 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Gout, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Taxifolin blocks monosodium urate crystal-induced gouty inflammation.Jul 31, 2022

Pubmed Data : Inflammopharmacology. 2022 Aug ;30(4):1335-1349. Epub 2022 Jun 16. PMID: 35708797
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Gout, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

The ethanolic extract of L. passerina and goyazensolide can be considered promising agents in the therapeutic of inflammation, hyperuricemia and gout.Feb 22, 2017

Pubmed Data : J Ethnopharmacol. 2017 Feb 23 ;198:444-450. Epub 2017 Jan 12. PMID: 28089739
Article Published Date : Feb 22, 2017
Study Type : Animal Study
Additional Links
Substances : Arnica
Diseases : Gout, Hyperuricemia, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

These results suggest that what we eat plays a role in our capacity to fine tune the inflammatory response.Dec 31, 2016

Pubmed Data : J Leukoc Biol. 2017 Jan ;101(1):275-284. Epub 2016 Aug 5. PMID: 27496979
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Fiber
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Total flavonoids of Humulus lupulus could be used as a promising drug or ingredient for treatment of hyperuricemia and gout.Feb 28, 2017

Pubmed Data : Pak J Pharm Sci. 2017 Mar ;30(2):493-497. PMID: 28649075
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Renoprotective, Uricosuric Agents
[+]

Triphala compares favorably to the drug Indomethacin as an anti-inflammatory against gouty arthritis while also improving antioxidant status. Jan 01, 2008

Pubmed Data : Vascul Pharmacol. 2008 Jan;48(1):14-20. Epub 2007 Nov 13. PMID: 18065272
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Triphala
Diseases : Gout
Additional Keywords : Natural Substances Versus Drugs
[+]

"Gout, uric acid and purine metabolism in paediatric nephrology."Jan 31, 1993

Pubmed Data : Pediatr Nephrol. 1993 Feb ;7(1):105-18. PMID: 8439471
Article Published Date : Jan 31, 1993
Study Type : Review
Additional Links
Diseases : Gout, Hyperuricemia, Uric Acid Nephropathy
Additional Keywords : Paediatric Nephrology
[+]

An in-depth view of potential dual effect of thymol in inhibiting xanthine oxidase activity.Aug 06, 2018

Pubmed Data : Int J Biol Macromol. 2018 Aug 7. Epub 2018 Aug 7. PMID: 30096398
Article Published Date : Aug 06, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Cancers: All, Gout, Hyperuricemia
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Antigout effects of Plantago asiatica.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:1364617. Epub 2018 Feb 22. PMID: 29681967
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Plantago asiatica
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Antioxidant, xanthine oxidase, α-amylase and α-glucosidase inhibitory activities of bioactive compounds from Rumex crispus root.Oct 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Oct 29 ;24(21). Epub 2019 Oct 29. PMID: 31671906
Article Published Date : Oct 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Yellow Dock
Diseases : Diabetes Mellitus: Type 2, Gout
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Antioxidants, Xanthine oxidase inhibitor
[+]

Bioactive compounds in garlic and black garlic as antigout agents, using computer simulation.Jul 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 Jul 27 ;12(8). Epub 2022 Jul 27. PMID: 36013310
Article Published Date : Jul 26, 2022
Study Type : In Vitro Study
Additional Links
Substances : Garlic
Diseases : Gout
[+]

Caffeic acid phenethyl ester suppresses NLRP3 inflammasome activation.Dec 08, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Dec 9 ;6:38622. Epub 2016 Dec 9. PMID: 27934918
Article Published Date : Dec 08, 2016
Study Type : In Vitro Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Cinnamon (cassia type) and Polygonum cuspidatum (source of resveratrol) demonstrated significant inhibition of xanthine oxidase indicating its potential use for the treatment of gout.Nov 01, 2000

Pubmed Data : J Ethnopharmacol. 2000 Nov;73(1-2):199-207. PMID: 11025157
Article Published Date : Nov 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon, Hu Zhang (Polygonum cuspidatum)
Diseases : Gout
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Coffee and vitamin C supplementation could be considered as preventive measures in patients with hyperuricemia and gout.Dec 01, 2008

Pubmed Data : Biosci Biotechnol Biochem. 2008 Dec;72(12):3148-57. Epub 2008 Dec 7. PMID: 20035225
Article Published Date : Dec 01, 2008
Study Type : Commentary
Additional Links
Substances : Coffee, Vitamin C
Diseases : Gout, Hyperuricemia
[+]

Curcumin inhibits xanthine oxidase.Jun 01, 2006

Pubmed Data : Nutrition. 2006 Jun;22(6):593-9. PMID: 19800788
Article Published Date : Jun 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Gout
Pharmacological Actions : Antioxidants, Enzyme Inhibitors, Xanthine oxidase inhibitor
[+]

Guava leaves extract could serve as functional food for managing gout and hypertensionFeb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Intercult Ethnopharmacol. 2016 Mar-Apr;5(2):122-30. Epub 2016 Mar 24. PMID: 27104032
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Guava
Diseases : Gout, Hypertension
Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Antioxidants, Xanthine oxidase inhibitor
[+]

has a narrow therapeutic index, with no clear-cut distinction between nontoxic, toxic, and lethal doses, causing substantial confusion among clinicians.Jun 01, 2010

Pubmed Data : Clin Toxicol (Phila). 2010 Jun;48(5):407-14. PMID: 20586571
Article Published Date : Jun 01, 2010
Study Type : Review
Additional Links
Diseases : Familial Mediterranean Fever, Gout
Problem Substances : Colchicine
[+]

Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2.Nov 30, 2020

Pubmed Data : Inflammopharmacology. 2020 Dec ;28(6):1481-1493. Epub 2020 Oct 1. PMID: 33006110
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Procyanidin B2
Diseases : Gout, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Mechanisms of theaflavins against gout and strategies for improving the bioavailability.May 31, 2023

Pubmed Data : Phytomedicine. 2023 Jun ;114:154782. Epub 2023 Mar 23. PMID: 36990009
Article Published Date : May 31, 2023
Study Type : Review
Additional Links
Substances : Theaflavins
Diseases : Gout
Pharmacological Actions : Matrix metalloproteinase-14 (MMP-14) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]

Noni fruit juice has an inhibitory effect on xanthine oxidase enzymes, supporting the traditional usage of noni in the treatment of gout and gout-like diseases. May 12, 2009

Pubmed Data : Phytother Res. 2009 May 12. PMID: 19434757
Article Published Date : May 12, 2009
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Gout, Pseudogout
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Pycnogenol selectively inhibits xanthine oxidase. Nov 01, 2000

Pubmed Data : J Agric Food Chem. 2000 Nov;48(11):5630-9. PMID: 11087530
Article Published Date : Nov 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Flavonoids, Pycnogenol (Pine Bark)
Diseases : Gout
Pharmacological Actions : Antioxidants, Xanthine oxidase inhibitor
Additional Keywords : Plant Extracts, Proanthocyanidins
[+]

Quercetin, Luteolin, and Silibinin inhibit the uric-acid associated enzyme xanthine oxidase. Apr 01, 2009

Pubmed Data : J Nat Prod. 2009 Apr;72(4):725-31. PMID: 19388706
Article Published Date : Apr 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Luteolin, Quercetin, Silibinin
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Xanthine oxidase inhibitor
[+]

Research progress of puerarin and its derivatives on anti-inflammatory and anti-gout activities.Sep 30, 2017

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2017 Oct ;42(19):3703-3708. PMID: 29235282
Article Published Date : Sep 30, 2017
Study Type : Review
Additional Links
Substances : Puerarin
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Natural Substances Versus Drugs
[+]

Review on pharmacological and toxicologyical effects of oleum azadirachti oil.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Biomed. 2013 Oct ;3(10):834-40. Epub 2013 Sep 4. PMID: 24075352
Article Published Date : Sep 30, 2013
Study Type : Review
Additional Links
Substances : Neem
Diseases : Asthma, Cardiovascular Diseases, Chickenpox, Colic, Conjunctivitis, Dysmenorrhea, Fever, Gastric Ulcer, Gout, Headache, Malaria, Muscle Soreness, Psoriasis, Rheumatism, Scabies
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Anti-Ulcer Agents, Antimicrobial, Antiviral Agents, Contraceptive Agents, Insect Repellents
Additional Keywords : Plant Oils
[+]

These data demonstrate the hyperuricemic effect of sugar-sweetened beverages and fructose.Feb 28, 2014

Pubmed Data : Pac Health Dialog. 2014 Mar ;20(1):31-8. PMID: 25928993
Article Published Date : Feb 28, 2014
Study Type : Review
Additional Links
Diseases : Gout, Hyperuricemia
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

This review explores the potential benefits of cherries and cherry products as a nonpharmacologic option for the treatment of gout.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Adv Musculoskelet Dis. 2019 ;11:1759720X19847018. Epub 2019 May 17. PMID: 31205513
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Cherry: All Varieties
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

This study suggests that chicory extract and chicoric acid may be used as promising therapeutic agents against gout.Oct 03, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 4 ;20(19). Epub 2019 Oct 4. PMID: 31590257
Article Published Date : Oct 03, 2019
Study Type : In Vitro Study
Additional Links
Substances : Chicory
Diseases : Gout
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Withaferin A, a compound found within Ashwaganda, exhibits a strong anti-inflammatory effect against gouty arthritis. Jan 01, 2008

Pubmed Data : J Pharm Pharm Sci. 2008;11(4):46-55. PMID: 19183513
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha
Diseases : Gout, Hyperuricemia
[+]

Vitamin C intake correlates inversely with uric acid levels, indicating its potential usefulness in treating gout.Sep 01, 2008

Pubmed Data : J Rheumatol. 2008 Sep;35(9):1853-1858. Epub 2008 May 1. PMID: 18464304
Article Published Date : Sep 01, 2008
Additional Links
Substances : Vitamin C
Diseases : Gout, Hyperuricemia

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