Graves Disease

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17 Substances Researched for Graves Disease
NameACCKFocus
Selenium541Locked
Vitamin D422Locked
Antioxidant formulas220Locked
Berberine110Locked
Bifidobacterium Longum 110Locked
Melatonin110Locked
NAC (N-acetyl-L-cysteine)110Locked
Quercetin110Locked
Vitamin C110Locked
Alpha-Lipoic Acid15Locked
Diosgenin23Locked
Curcumin12Locked
Luteolin12Locked
Peony12Locked
Prunella vulgaris12Locked
Puerarin12Locked
Lotus 11Locked
3 Problem Substances Researched for Graves Disease
NameACCKFocus
Gliadin330Locked
Gluten110Locked
Wheat110Locked
3 Problematic Actions Researched for Graves Disease
NameACCKFocus
Vaccination: All110Locked
Vaccination: HPV (Gardasil)110Locked
Vaccination: COVID-1914Locked

View the Evidence:
28 Abstracts with Graves Disease Research

[+]

Probiotic Bifidobacterium longum supplied with methimazole improved the thyroid function of Graves' disease patients through the gut-thyroid axis Jan 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Commun Biol. 2021 09 7 ;4(1):1046. Epub 2021 Sep 7. PMID: 34493790
Article Published Date : Jan 06, 2021
Study Type : Human Study
Additional Links
Substances : Bifidobacterium Longum
Diseases : Graves Disease
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Antioxidant supplementation improves the effect of methimazole therapy in the treatment of Grave's disease. Jan 01, 2005

Pubmed Data : Clin Chem Lab Med. 2005;43(4):383-8. PMID: 15899653
Article Published Date : Jan 01, 2005
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas
Diseases : Graves Disease
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Celiac disease is far higher in those diagnosed with Grave's disease.Oct 01, 2006

Pubmed Data : Endocrine. 2006 Oct;30(2):175-83. PMID: 17322576
Article Published Date : Oct 01, 2006
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases, Celiac Disease, Graves Disease, Hyperthyroidism
Additional Keywords : Anti-Gliadin Antibodies, Diseases that are Linked
Problem Substances : Gliadin, Gluten, Wheat
[+]

Graves Disease may occur following the quadrivalent HPV vaccine.Jun 29, 2012

Pubmed Data : Vaccine. 2012 Jun 29 ;30(31):4585-7. Epub 2012 May 11. PMID: 22580356
Article Published Date : Jun 29, 2012
Study Type : Human Study
Additional Links
Diseases : Graves Disease
Anti Therapeutic Actions : Vaccination: All, Vaccination: HPV (Gardasil)
[+]

Lower serum 25-hydroxyvitamin D levels were associated with a higher incidence of Graves disease recurrence.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2017 Aug ;96(31):e7700. PMID: 28767604
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Graves Disease, Graves Disease: Prevention, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Melatonin, quercetin and NAC are beneficial in reducing oxidative stress in the patients with Grave's Disease. Sep 01, 2005

Pubmed Data : Pharmazie. 2005 Sep;60(9):696-700. PMID: 16222871
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Melatonin, NAC (N-acetyl-L-cysteine), Quercetin
Diseases : Graves Disease
Pharmacological Actions : Antioxidants
[+]

Reaching optimal selenium and vitamin D levels increases the early efficacy of methimazole treatment when selenium and vitamin D levels are suboptimal.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2022 ;13:886451. Epub 2022 Jun 15. PMID: 35784564
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Selenium, Vitamin D
Diseases : Graves Disease, Mineral Deficiencies: Selenium, Vitamin D Deficiency
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Selenium supplementation can enhance biochemical restoration of hyperthyroidism.May 31, 2015

Pubmed Data : Eur Thyroid J. 2015 Jun ;4(2):93-8. Epub 2015 May 27. PMID: 26279994
Article Published Date : May 31, 2015
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : Graves Disease, Hyperthyroidism, Thyrotoxicosis
[+]

Selenium supplementation can enhance the effect of antithyroid drugs in patients with recurrent Graves' disease.Jul 07, 2016

Pubmed Data : Horm Metab Res. 2016 Jul 8. Epub 2016 Jul 8. PMID: 27392116
Article Published Date : Jul 07, 2016
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : Graves Disease, Hyperthyroidism
Additional Keywords : Risk Reduction
[+]

Supplementation with antioxidants, and particularly selenium, is of benefit in patients with Grave's disease. Mar 01, 2004

Pubmed Data : Clin Chim Acta. 2004 Mar;341(1-2):55-63. PMID: 14967159
Article Published Date : Mar 01, 2004
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas, Selenium
Diseases : Graves Disease
[+]

The potential prebiotic berberine combined with methimazole improved the therapeutic effect of Graves' disease patients.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2021 ;12:826067. Epub 2022 Jan 10. PMID: 35082799
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Berberine
Diseases : Graves Disease
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

There is a higher prevalance of celiac disease and gluten sensitivity in patients with Grave's hyperthyroidism.Mar 01, 2005

Pubmed Data : Clin Endocrinol (Oxf). 2005 Mar;62(3):303-6. PMID: 15730411
Article Published Date : Mar 01, 2005
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases, Celiac Disease, Gluten Sensitivity, Graves Disease, Hyperthyroidism
Problem Substances : Gliadin
[+]

There is evidence that intolerance to wheat (measured by CD associated anti-endomysial antibodies) may play a role in Graves' disease.Jan 01, 1999

Pubmed Data : Digestion. 1999 Jan-Feb;60(1):86-8. PMID: 9892805
Article Published Date : Jan 01, 1999
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Graves Disease
Additional Keywords : Diseases that are Linked
Problem Substances : Gliadin
Adverse Pharmacological Actions : Immunotoxic
[+]

Vitamin C supplementation relieves oxidative stress in propylthiouracil treated hyperthyroid patients. Oct 01, 1998

Pubmed Data : Clin Chem Lab Med. 1998 Oct;36(10):767-70. PMID: 9853803
Article Published Date : Oct 01, 1998
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Graves Disease, Hyperthyroidism
[+]

Wheat intolerance may play a key role in autoimmune thyroid diseases. Dec 01, 2003

Pubmed Data : Hepatogastroenterology. 2003 Dec;50 Suppl 2:cclxxix-cclxxx. PMID: 15244201
Article Published Date : Dec 01, 2003
Study Type : Human Study
Additional Links
Diseases : Autoimmune Thyroiditis, Gluten Sensitivity, Graves Disease, Hashimoto's thyroiditis
[+]

Alpha-lipoic acid could be a therapeutic agent because of its inhibitory effects on ROS production, inflammation, and adipose tissue expansionDec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2016 Jan ;95(2):e2497. PMID: 26765462
Article Published Date : Dec 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Graves Disease, Oxidative Stress
Pharmacological Actions : Anti-Adipogenic, Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Gene Expression Regulation
[+]

Development of Graves' disease after SARS-CoV-2 mRNA vaccination.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2021 ;9:778964. Epub 2021 Nov 23. PMID: 34888290
Article Published Date : Dec 31, 2020
Study Type : Human: Case Report, Review
Additional Links
Diseases : Coronavirus Infection, Graves Disease, Thyroid Dysfunction
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: COVID-19
[+]

Mechanism of Prunella vulgaris L. and luteolin in restoring Tfh/Tfr balance and alleviating oxidative stress in Graves' disease.Aug 31, 2024

Pubmed Data : Phytomedicine. 2024 Sep ;132:155818. Epub 2024 Jun 11. PMID: 38879922
Article Published Date : Aug 31, 2024
Study Type : Animal Study
Additional Links
Substances : Luteolin, Prunella vulgaris
Diseases : Graves Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

Puerarin may have the potential to mitigate Graves' disease by inhibiting inflammatory and oxidative stress.Jan 28, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Pediatr. 2024 Jan 29 ;13(1):38-51. Epub 2024 Jan 24. PMID: 38323179
Article Published Date : Jan 28, 2024
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Graves Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Study on protective effects and mechanisms of total glucosides of Paeony on Graves disease.Mar 06, 2023

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2023 Mar 7 ;103(9):689-695. PMID: 36858370
Article Published Date : Mar 06, 2023
Study Type : Animal Study
Additional Links
Substances : Peony
Diseases : Graves Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-2 Downregulation
[+]

The protective effect of curcumin to PTU-induced hepatotoxicity is attributed to its antioxidative properties.Oct 23, 2018

Pubmed Data : Food Chem Toxicol. 2018 Oct 24 ;123:169-180. Epub 2018 Oct 24. PMID: 30367912
Article Published Date : Oct 23, 2018
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Graves Disease, Hyperthyroidism
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Epigenetic Modification
[+]

Transcriptome analysis of the effect of diosgenin on autoimmune thyroiditis.Jan 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 03 18 ;11(1):6401. Epub 2021 Mar 18. PMID: 33737640
Article Published Date : Jan 17, 2021
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Autoimmune Thyroiditis, Graves Disease
Pharmacological Actions : MicroRNA modulator
Additional Keywords : Gene Expression Regulation
[+]

22 immune diseases diagnosed at hospitalization correlated with obesityApr 30, 2012

Pubmed Data : Ann Med. 2012 May ;44(3):289-95. Epub 2011 Feb 1. PMID: 21284531
Article Published Date : Apr 30, 2012
Study Type : Review
Additional Links
Diseases : Asthma, Autoimmune Diseases, Behcet Disease, Graves Disease, Hashimoto's thyroiditis, Obesity, Psoriasis
[+]

Diosgenin From Dioscorea nipponica rhizoma against Graves' disease-on network pharmacology and experimental evaluation.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:806829. Epub 2022 Jan 24. PMID: 35140607
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Diosgenin
Diseases : Graves Disease
Pharmacological Actions : Apoptotic
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Experimental studies in humans have suggested beneficial effects of vitamin D supplementation in reducing the severity of autoimmune diseases.Jan 08, 2017

Pubmed Data : Rev Endocr Metab Disord. 2017 Jan 9. Epub 2017 Jan 9. PMID: 28070798
Article Published Date : Jan 08, 2017
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Addison's Disease, Autoimmune Diseases, Endocrine Diseases, Graves Disease, Hashimoto's thyroiditis, Vitamin D Deficiency
Additional Keywords : Risk Factors, Risk Reduction
[+]

Immunomodulatory function of vitamin D and its role in autoimmune thyroid disease.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2021 ;12:574967. Epub 2021 Feb 19. PMID: 33679732
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Graves Disease, Hashimoto's thyroiditis, Thyroid Diseases, Vitamin D Deficiency
Pharmacological Actions : Immunomodulatory
[+]

Neferine suppresses autophagy-induced inflammation, oxidative stress and adipocyte differentiation in Graves' orbitopathy.Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2021 Jan 14. Epub 2021 Jan 14. PMID: 33443817
Article Published Date : Jan 13, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Graves Disease
Pharmacological Actions : Anti-Adipogenic, Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
[+]

Selenium and selenoproteins in immune mediated thyroid disorders.Oct 03, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diagnostics (Basel). 2018 Oct 4 ;8(4). Epub 2018 Oct 4. PMID: 30287753
Article Published Date : Oct 03, 2018
Study Type : Review
Additional Links
Substances : Selenium
Diseases : Graves Disease, Thyroid Diseases
Pharmacological Actions : Immunomodulatory

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