Head and Neck Cancer

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55 Substances Researched for Head and Neck Cancer
NameACCKFocus
Honey340Locked
Curcumin1928Locked
Aloe Vera220Locked
Cannabis220Locked
Coffee211Locked
Green Tea211Locked
Anthocyanins110Locked
Antioxidants: Fat Soluble110Locked
Arginine110Locked
Fiber110Locked
Flavonoids110Locked
Folate110Locked
Glutamine110Locked
Licorice110Locked
Neem110Locked
Silver (nanoparticles)110Locked
St. Johns Wort110Locked
Thyme110Locked
Tocopherols110Locked
Turmeric110Locked
Vitamin C110Locked
Zataria multiflora110Locked
EGCG (Epigallocatechin gallate)69Locked
Resveratrol58Locked
Honokiol57Locked
Crocin15Locked
Deguelin23Locked
Sulforaphane33Locked
Berbamine12Locked
Lupeol12Locked
Lycopene12Locked
Silibinin12Locked
Wogonin12Locked
6-Shogaol11Locked
Berberine11Locked
Broccoli Sprouts11Locked
Cafestol11Locked
Caffeic Acid11Locked
Caffeic acid phenethyl ester11Locked
Cinnamon11Locked
Fisetin11Locked
Fucoidan11Locked
Genistein11Locked
Gold (nanoparticles)11Locked
Grape Seed Extract11Locked
MSM (Methylsulfonylmethane)11Locked
Melatonin11Locked
Piperlongumine 11Locked
Proanthocyanidins11Locked
Quercetin11Locked
Sandalwood11Locked
Sweet Potato11Locked
Thymoquinone11Locked
Vitamin A11Locked
Vitamin D11Locked
2 Problem Substances Researched for Head and Neck Cancer
NameACCKFocus
Meat110Locked
Morphine12Locked
5 Therapeutic Actions Researched for Head and Neck Cancer
NameACCKFocus
Hyperbaric Treatment230Locked
Laser Treatment: Low-Level211Locked
Dietary Modification: Low Carbohydrate/Ketogenic110Locked
Dietary Modification: Mediterranean Diet110Locked
Photodynamic therapy11Locked
2 Problematic Actions Researched for Head and Neck Cancer
NameACCKFocus
Radiotherapy313Locked
Mobile Phone Radiation15Locked
Related Topics

Head and Neck Cancer is a Sub of the following Topic

View the Evidence:
108 Abstracts with Head and Neck Cancer Research

[+]

Hyperbaric oxygenation for tumour sensitisation to radiotherapy.Jan 10, 2018

Pubmed Data : Cochrane Database Syst Rev. 2018 04 11 ;4:CD005007. Epub 2018 Apr 11. PMID: 29637538
Article Published Date : Jan 10, 2018
Study Type : Meta Analysis, Review
Additional Links
Diseases : Head and Neck Cancer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Radiosensitizer
[+]

Oral administration of honey after radiotherapy could prevent moderate to severe mucositis and associated weight loss.Mar 15, 2015

Pubmed Data : Laryngoscope. 2015 Mar 16. Epub 2015 Mar 16. PMID: 25778825
Article Published Date : Mar 15, 2015
Study Type : Meta Analysis
Additional Links
Substances : Honey
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
Additional Keywords : Significant Treatment Outcome
[+]

Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Head Neck. 2019 Jan ;41(1):E11-E16. Epub 2018 Dec 11. PMID: 30537286
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Silver (nanoparticles)
Diseases : Cancer Metastasis, Head and Neck Cancer
Additional Keywords : Spontaneous Tumor Regression
[+]

Aloe vera mouthwash was as beneficial as benzydamine mouthwash in alleviating the severity of radiation-induced mucositis.Dec 31, 2014

Pubmed Data : Oral Health Prev Dent. 2015 ;13(4):309-15. PMID: 25431805
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
[+]

An extract of Glycyrrhiza can be effective for decreasing the severity of oral mucositis in head and neck cancer patients undergoing radiotherapy.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent (Tehran). 2017 Sep ;14(5):267-274. PMID: 29296112
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Licorice
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Assessment of oxidative stress in tumors and histologically normal mucosa from patients with head and neck squamous cell carcinoma: a preliminary study.Mar 11, 2013

Pubmed Data : Eur J Cancer Prev. 2013 Mar 12. Epub 2013 Mar 12. PMID: 23492956
Article Published Date : Mar 11, 2013
Study Type : Human Study
Additional Links
Substances : Antioxidants: Fat Soluble, Tocopherols
Diseases : Head and Neck Cancer, Skin Cancer
Pharmacological Actions : Chemopreventive
[+]

Chamomile gel versus urea cream to prevent acute radiation dermatitis in head and neck cancer patients.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2020 Jan-Dec;19:1534735420962174. PMID: 32985288
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Chamomile
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer
Pharmacological Actions : Radioprotective
[+]

Coffee drinking is associated with a lower risk of colorectal, liver, female breast and head and neck cancer.Jul 26, 2017

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2017 Jul 27. Epub 2017 Jul 27. PMID: 28751477
Article Published Date : Jul 26, 2017
Study Type : Human Study
Additional Links
Substances : Coffee
Diseases : Breast Cancer, Cancer Mortality, Cancers: All, Colorectal Cancer, Head and Neck Cancer, Liver Cancer
Pharmacological Actions : Chemopreventive
[+]

Glutamine significantly decreased mucositis severity in the oral cavity, pharynx and larynx induced by chemoradiotherapy.Oct 22, 2014

Pubmed Data : Oncol Rep. 2014 Oct 23. Epub 2014 Oct 23. PMID: 25351453
Article Published Date : Oct 22, 2014
Study Type : Human Study
Additional Links
Substances : Glutamine
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Chemotherapeutic, Radioprotective
[+]

Higher dietary fiber intake, prior to the initiation of treatment, may prolong survival time, in those with a new head and neck cancer diagnosis.Sep 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Sep 27 ;11(10). Epub 2019 Sep 27. PMID: 31569808
Article Published Date : Sep 26, 2019
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Cancer Mortality, Head and Neck Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Low-level laser therapy seems to be effective to mitigate salivary hypofunction and increase salivary pH of patients submitted to radiotherapy.Mar 02, 2017

Pubmed Data : Lasers Med Sci. 2017 Mar 3. Epub 2017 Mar 3. PMID: 28258315
Article Published Date : Mar 02, 2017
Study Type : Human Study
Additional Links
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Radioprotective
[+]

Moderate marijuana use is associated with reduced risk of head and neck squamous cell carcinoma.Aug 01, 2009

Pubmed Data : Cancer Prev Res (Phila Pa). 2009 Aug;2(8):759-68. Epub 2009 Jul 28. PMID: 19638490
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : Cannabis
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemopreventive
[+]

Neem oil and St. Johns Wort proved to be a safe and effective option in the management of acute skin toxicity in head and neck cancer patients.Jan 31, 2017

Pubmed Data : Med Oncol. 2017 Feb ;34(2):30. Epub 2017 Jan 18. PMID: 28101834
Article Published Date : Jan 31, 2017
Study Type : Human Study
Additional Links
Substances : Neem, St. Johns Wort
Diseases : Chemotherapy and Radiation Toxicity, Chemotherapy-Induced Toxicity: Cisplatin, Head and Neck Cancer
Pharmacological Actions : Chemoprotective Agents, Radioprotective
[+]

Perioperative arginine-supplemented nutrition in malnourished patients with head and neck cancer improves long-term survival.Nov 01, 2010

Pubmed Data : Am J Clin Nutr. 2010 Nov;92(5):1151-6. Epub 2010 Sep 29. PMID: 20881073
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Head and Neck Cancer
[+]

Processed meat intake was positively associated with head-neck cancer.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Causes Control. 2017 Jun ;28(6):647-656. Epub 2017 Apr 5. PMID: 28382514
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Head and Neck Cancer, Oral Cancer
Additional Keywords : Risk Factors
Problem Substances : Meat
[+]

Prophylactic use of an aloe vera-based cream-based cream is thus effective in delaying radiation dermatitis in head and neck cancer.Jun 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2017 Jun 24 ;4(3). Epub 2017 Jun 24. PMID: 28930258
Article Published Date : Jun 23, 2017
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer
Pharmacological Actions : Radioprotective
[+]

Protective effect of Punica granatum extract in head and neck cancer patients undergoing radiotherapy.Sep 30, 2019

Pubmed Data : Indian J Otolaryngol Head Neck Surg. 2019 Oct ;71(Suppl 1):318-320. Epub 2018 Mar 15. PMID: 31741979
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Tea consumption may protect against the development of second esophageal neoplasms among head and neck squamous-cell carcinoma patients.Mar 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2019 Mar 19 ;11(3). Epub 2019 Mar 19. PMID: 30893904
Article Published Date : Mar 18, 2019
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Esophageal Cancer, Head and Neck Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

The effectiveness of thyme honey for the management of treatment-induced xerostomia in head and neck cancer patients.Mar 31, 2017

Pubmed Data : Eur J Oncol Nurs. 2017 Apr ;27:1-8. Epub 2017 Jan 16. PMID: 28279391
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : Head and Neck Cancer, Xerostomia
Pharmacological Actions : Radioprotective
[+]

The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study.Oct 30, 2013

Article Published Date : Oct 30, 2013
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Head and Neck Cancer, Mucositis, Radiation Induced Illness, Radiation Induced Illness: Mucositis, Radiotherapy
Anti Therapeutic Actions : Radiotherapy
[+]

The ketogenic diet let to a decline in the lactate concentration in tumor tissue.Dec 31, 2012

Pubmed Data : Nutr Cancer. 2013 ;65(6):843-9. PMID: 23909728
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Diseases : Head and Neck Cancer
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Chemotherapeutic
[+]

The Mediterranean diet acts protectively against head and neck cancer overall and by cancer subsite.Jul 31, 2016

Pubmed Data : Eur J Cancer Prev. 2016 Aug 1. Epub 2016 Aug 1. PMID: 27483412
Article Published Date : Jul 31, 2016
Study Type : Human Study
Additional Links
Diseases : Head and Neck Cancer
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

The study provided evidence on the positive effect of thyme honey on the management of radiation-induced oral mucositis.May 31, 2018

Pubmed Data : Eur J Oncol Nurs. 2018 Jun ;34:89-97. Epub 2018 Apr 30. PMID: 29784145
Article Published Date : May 31, 2018
Study Type : Human Study
Additional Links
Substances : Honey, Thyme
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

These findings provide evidence of the protective role of dietary folate intake on head and neck cancer risk.Nov 20, 2017

Pubmed Data : Br J Cancer. 2017 Nov 21. Epub 2017 Nov 21. PMID: 29161239
Article Published Date : Nov 20, 2017
Study Type : Human Study
Additional Links
Substances : Folate
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

These findings support evidence of a protective role of dietary fiber on head and neck cancer risk.Jan 28, 2019

Pubmed Data : Int J Cancer. 2019 Jan 29. Epub 2019 Jan 29. PMID: 30693489
Article Published Date : Jan 28, 2019
Study Type : Human Study
Additional Links
Substances : Fiber
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

These results indicate that flavonoid intake is associated with lower head and neck cancer risk.Jul 18, 2017

Pubmed Data : J Nutr. 2017 Jul 19. Epub 2017 Jul 19. PMID: 28724656
Article Published Date : Jul 18, 2017
Study Type : Human Study
Additional Links
Substances : Anthocyanins, Flavonoids
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Risk Reduction
[+]

This population-based study did not find a statistically significant increase in the risk of head and neck cancer in young adults from cannabis use.Feb 29, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Otolaryngol Head Neck Surg. 2008 Mar ;138(3):374-80. PMID: 18312888
Article Published Date : Feb 29, 2008
Study Type : Human Study
Additional Links
Substances : Cannabis
Diseases : Head and Neck Cancer
Additional Keywords : Risk Factors
[+]

This study indicates the feasibility of combining hyperbaric oxygen with chemoradiation.Feb 28, 2017

Pubmed Data : Int J Radiat Oncol Biol Phys. 2017 Mar 1 ;97(3):481-486. Epub 2016 Nov 15. PMID: 28126298
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Radiosensitizer
Additional Keywords : Significant Treatment Outcome
[+]

This study showed an inverse association between intake of vitamin C and the incidence of HNC and HNC-subtypes.Jul 07, 2015

Pubmed Data : Am J Clin Nutr. 2015 Jul 8. Epub 2015 Jul 8. PMID: 26156734
Article Published Date : Jul 07, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Head and Neck Cancer
Additional Keywords : Risk Factors, Risk Reduction
[+]

Turmeric extract reduces the incidence and severity of radiation-induced mucositis.Feb 06, 2020

Pubmed Data : J Laryngol Otol. 2020 Feb 7:1-6. Epub 2020 Feb 7. PMID: 32029014
Article Published Date : Feb 06, 2020
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
[+]

Zataria mouthwash effectively decreases the severity of oral mucositis and mouth pain in patients with head and neck cancer treated with radiotherapy.Jun 30, 2018

Pubmed Data : Clin Oral Investig. 2018 Jul ;22(6):2263-2272. Epub 2018 Jan 8. PMID: 29313134
Article Published Date : Jun 30, 2018
Study Type : Human Study
Additional Links
Substances : Zataria multiflora
Diseases : Head and Neck Cancer, Radiation Induced Illness: Mucositis
Pharmacological Actions : Radioprotective
Additional Keywords : Plant Extracts
[+]

Crocin can be considered as a potential drug and sensitizer in cancer treatment. Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2017 ;16(1):230-237. PMID: 28496478
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Crocin
Diseases : Head and Neck Cancer
Pharmacological Actions : Radiosensitizer
[+]

This investigation reveals that cell-phone radiofrequency could enhance head and neck cancer by stimulating angiogenesis and cell invasion.May 12, 2018

Pubmed Data : Head Neck. 2018 May 13. Epub 2018 May 13. PMID: 29756334
Article Published Date : May 12, 2018
Study Type : Human In Vitro
Additional Links
Diseases : Head and Neck Cancer
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Mobile Phone Radiation
[+]

Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma. Oct 01, 2010

Pubmed Data : Mol Cancer Ther. 2010 Oct;9(10):2665-75. PMID: 20937593
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Drug Synergy
[+]

Curcumin is a potential radio-enhancer in head and neck cancer.Oct 01, 2009

Pubmed Data : Laryngoscope. 2009 Oct;119(10):2019-26. PMID: 19655336
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Radiosensitizer
[+]

Curcumin suppresses growth of head and neck squamous cell carcinoma.Oct 01, 2005

Pubmed Data : Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6994-7002. PMID: 16203793
Article Published Date : Oct 01, 2005
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
Pharmacological Actions : Antineoplastic Agents, NF-kappaB Inhibitor
[+]

Curcumin suppresses the growth of head and neck squamous cell cancer. Oct 01, 2008

Pubmed Data : Clin Cancer Res. 2008 Oct 1;14(19):6228-36. PMID: 18829502
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antineoplastic Agents, NF-kappaB Inhibitor
[+]

Curcumin, resveratrol, and EGCG, repolarizes tumor-associated macrophages and triggers an immune response to cause suppression of HPV+ tumors.Feb 15, 2018

Pubmed Data : Cancer Immunol Immunother. 2018 Feb 16. Epub 2018 Feb 16. PMID: 29453519
Article Published Date : Feb 15, 2018
Study Type : Animal Study
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Resveratrol
Diseases : Head and Neck Cancer, Human Papillomavirus (HPV)
Pharmacological Actions : Immunomodulatory
Additional Keywords : Natural Substance Synergy
[+]

Deguelin may represent a novel and effective chemo-agent against head and neck squamous cell carcinoma.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(1):e54736. Epub 2013 Jan 23. PMID: 23372762
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Deguelin
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

Honokiol may induce apoptosis and inhibit the survival/proliferation signaling pathways in oral CSC-like cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cancer. 2016 ;16(1):245. Epub 2016 Mar 24. PMID: 27012679
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Head and Neck Cancer, Oral Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Cancer Stem Cells, Targeting Cancer Stem Cells With NonToxic Therapies
[+]

In vitro and in vivo superior radiosensitizing effect of berbamine for head and neck squamous cell carcinoma.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2018 ;11:8117-8125. Epub 2018 Nov 14. PMID: 30532553
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berbamine
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Radiosensitizer
[+]

Intra-tumoral injection of TriCurin significantly inhibited tumor growth by 85.5%.Jul 15, 2016

Pubmed Data : Oncotarget. 2016 Jul 16. Epub 2016 Jul 16. PMID: 27437871
Article Published Date : Jul 15, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Resveratrol
Diseases : Head and Neck Cancer, Human Papillomavirus (HPV)
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemopreventive, Tumor Suppressor Protein p53 Upregulation
[+]

Lactoferrin inhibits growth of malignant tumors of the head and neck.Aug 31, 2003

Pubmed Data : ORL J Otorhinolaryngol Relat Spec. 2003 Sep-Oct;65(5):245-9. PMID: 14730178
Article Published Date : Aug 31, 2003
Study Type : Animal Study
Additional Links
Substances : Lactoferrin
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Immunomodulatory
[+]

Lupeol may orchestrate a bifurcated regulation of neoplastic growth and apoptosis in head and neck cancers.Mar 31, 2017

Pubmed Data : Cell Oncol (Dordr). 2017 Apr ;40(2):145-155. Epub 2016 Dec 30. PMID: 28039610
Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lupeol
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

Lycopene and curcumin given 24 hours before irradiation reduced the structural damage to the salivary glands.Jan 27, 2016

Pubmed Data : Br J Oral Maxillofac Surg. 2016 Jan 28. Epub 2016 Jan 28. PMID: 26830066
Article Published Date : Jan 27, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin, Lycopene
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer
Pharmacological Actions : Radioprotective
Anti Therapeutic Actions : Radiotherapy
[+]

Morphine can inhibit dendritic cell-mediated anti-tumor immunity by suppressing DC maturation and function.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Cancer Res. 2016 ;6(2):157-72. Epub 2016 Jan 15. PMID: 27186393
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Breast Cancer, Head and Neck Cancer, Lung Cancer
Problem Substances : Morphine
Adverse Pharmacological Actions : Immunosuppressive
[+]

Piperlongumine inhibits head and neck squamous cell carcinoma proliferation by docking to Akt.Aug 14, 2020

Pubmed Data : Phytother Res. 2020 Aug 15. Epub 2020 Aug 15. PMID: 32798277
Article Published Date : Aug 14, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative
[+]

Silibinin inhibited tumor aggressiveness in head and neck squamous cell carcinomas.Jun 07, 2015

Pubmed Data : Oncotarget. 2015 Jun 8. Epub 2015 Jun 8. PMID: 26090866
Article Published Date : Jun 07, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , MicroRNA modulator
Additional Keywords : Dose Response
[+]

Targeting survivin using honokiol in combination with radiation therapy may provide novel therapeutic opportunities.Feb 14, 2018

Pubmed Data : Clin Cancer Res. 2018 Feb 15 ;24(4):858-869. Epub 2017 Nov 27. PMID: 29180609
Article Published Date : Feb 14, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Radiosensitizer
[+]

The oral administration of formononetin decelerated tumor growth through.Jan 31, 2020

Pubmed Data : Oncol Rep. 2020 Feb ;43(2):700-710. Epub 2019 Dec 13. PMID: 31894318
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic
[+]

This study demonstrates potent in vitro and in vivo anticancer activity of curcumin in a SIRT1-dependent fashion.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:13429. Epub 2015 Aug 24. PMID: 26299580
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, NF-kappaB Inhibitor, SIRT1 Activator
[+]

This study proposes a novel molecular rationale for antitumor activities of green tea in head and neck cancers.Nov 14, 2016

Pubmed Data : Phytomedicine. 2016 Nov 15 ;23(12):1344-1355. Epub 2016 Aug 19. PMID: 27765354
Article Published Date : Nov 14, 2016
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Head and Neck Cancer
Pharmacological Actions : Apoptotic, MicroRNA modulator
[+]

Treatment of HNSCC cells with combinations of CUR and RES can be more effective in inhibiting in vivo and in vitro cancer cell growth than the treatment with CUR alone.Nov 14, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2014 Nov 15 ;5(21):10745-62. PMID: 25296980
Article Published Date : Nov 14, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Natural Substance Synergy
[+]

Wogonin significantly sensitized resistant HNC cells to cisplatin both in vitro and in vivo. Aug 19, 2016

Pubmed Data : Apoptosis. 2016 Aug 20. Epub 2016 Aug 20. PMID: 27544755
Article Published Date : Aug 19, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Head and Neck Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Selective Cytotoxicity
[+]

6-shogaol induces apoptosis and enhances radiosensitivity in head and neck squamous cell carcinoma cell lines.Nov 22, 2017

Pubmed Data : Phytother Res. 2017 Nov 23. Epub 2017 Nov 23. PMID: 29168275
Article Published Date : Nov 22, 2017
Study Type : In Vitro Study
Additional Links
Substances : 6-Shogaol
Diseases : Head and Neck Cancer
Pharmacological Actions : Apoptotic, Radiosensitizer
[+]

A review of the biological and therapeutic activities, and anticancer properties of curcumin.Oct 31, 2015

Pubmed Data : Exp Ther Med. 2015 Nov ;10(5):1615-1623. Epub 2015 Sep 17. PMID: 26640527
Article Published Date : Oct 31, 2015
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Arthritis, Head and Neck Cancer, Liver Cancer, Lung Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Skin Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antimutagenic Agents, Apoptotic, Cell cycle arrest
[+]

An overview of the therapeutic effects of curcumol in several diseases.Apr 13, 2020

Pubmed Data : Nutr Cancer. 2020 Apr 14:1-15. Epub 2020 Apr 14. PMID: 32285707
Article Published Date : Apr 13, 2020
Study Type : Review
Additional Links
Substances : Curcumol
Diseases : Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Berberine may have potential applications as a chemotherapeutic agent for the management of head and neck squamous carcinoma.Sep 24, 2015

Pubmed Data : Oncol Rep. 2015 Sep 25. Epub 2015 Sep 25. PMID: 26503508
Article Published Date : Sep 24, 2015
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Head and Neck Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Suppressor Protein p53 Upregulation
[+]

Betulinic acid a radiosensitizer in head and neck squamous cell carcinoma cell lines.Feb 28, 2010

Pubmed Data : Strahlenther Onkol. 2010 Mar ;186(3):143-8. Epub 2010 Feb 22. PMID: 20339825
Article Published Date : Feb 28, 2010
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Radiosensitizer
[+]

Betulinic acid has apoptotic activity against head and neck squamous cell carcinoma.Aug 31, 2003

Pubmed Data : Head Neck. 2003 Sep ;25(9):732-40. PMID: 12953308
Article Published Date : Aug 31, 2003
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Apoptotic
[+]

Biochanin-A induces apoptosis and suppresses migration in FaDu human pharynx squamous carcinoma cells.Oct 31, 2017

Pubmed Data : Oncol Rep. 2017 Nov ;38(5):2985-2992. Epub 2017 Sep 13. PMID: 28901495
Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Biochanin A
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Broccoli extract improves chemotherapeutic drug efficacy against head-neck squamous cell carcinomas.Aug 03, 2018

Pubmed Data : Med Oncol. 2018 Aug 4 ;35(9):124. Epub 2018 Aug 4. PMID: 30078069
Article Published Date : Aug 03, 2018
Study Type : In Vitro Study
Additional Links
Substances : Broccoli Sprouts, Sulforaphane
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

Caffeic acid and caffeic acid phenethyl ester Induction of cell cycle arrest and apoptotic response of head and neck squamous carcinoma cells.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:6793456. Epub 2017 Jan 12. PMID: 28167973
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Caffeic acid phenethyl ester
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Combination of photodynamic therapy and Sulforaphane led to enhanced cytotoxic effect on head and neck cancer cells.Dec 31, 2014

Pubmed Data : Gen Physiol Biophys. 2015 Jan ;34(1):13-21. Epub 2014 Nov 14. PMID: 25395599
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Head and Neck Cancer
Therapeutic Actions : Photodynamic therapy
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Cytotoxic
[+]

Curcumin attenuates all stages of tumour progression and provides chemosensitisation to cisplatin and protection from its ototoxic adverse effects.Oct 14, 2015

Pubmed Data : Br J Cancer. 2015 Oct 15. Epub 2015 Oct 15. PMID: 26469832
Article Published Date : Oct 14, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemoprotective Agents, Chemosensitizer, NF-E2-Related Factor-2 (Nrf2) Modulator, STAT3 Inhibitor
[+]

Curcumin demonstrates promising therapeutic potential as a new treatment modality for head and neck cancer management.Oct 26, 2015

Pubmed Data : ACS Comb Sci. 2015 Oct 27. Epub 2015 Oct 27. PMID: 26505786
Article Published Date : Oct 26, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemotherapeutic, Cyclin D1 Down-Regulation, P21 Activation
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin
[+]

Curcumin down-regulates the PI3K-AKT-mTOR pathway and inhibits growth and progression in head and neck cancer cells. Jul 05, 2020

Pubmed Data : Phytother Res. 2020 Jul 6. Epub 2020 Jul 6. PMID: 32628350
Article Published Date : Jul 05, 2020
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative
[+]

Curcumin inhibits carcinogen and nicotine-induced head and neck squamous cell carcinoma.Dec 01, 2010

Pubmed Data : Cancer Prev Res (Phila). 2010 Dec;3(12):1586-95. Epub 2010 Sep 17. PMID: 20851953
Article Published Date : Dec 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
[+]

Curcumin inhibits head and neck cancer cell proliferation.Sep 15, 2006

Pubmed Data : Int J Cancer. 2006 Sep 15;119(6):1268-75. PMID: 16642480
Article Published Date : Sep 15, 2006
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Interleukin-6 Downregulation
[+]

Curcumin inhibits head and neck squamous cell cancer cells.Sep 20, 2004

Pubmed Data : Int J Cancer. 2004 Sep 20;111(5):679-92. PMID: 15252836
Article Published Date : Sep 20, 2004
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer, Skin Cancer: Squamous Cell
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Antiproliferative , Apoptotic, NF-kappaB Inhibitor
[+]

Curcumin is a multi-targeting agent, simultaneously activating the tumor suppressor p53/p73 pathways and inhibiting pro-apoptotic p-AKT and Bcl-2 levels. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(4):e0124218. Epub 2015 Apr 24. PMID: 25910231
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Carcinoma: Non-Small-Cell Lung, Head and Neck Cancer, Head and Neck Neoplasms, Lung Cancer, Lung Cancer: Metastatic
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Tumor Suppressor Protein p53 Upregulation
[+]

Curcumin suppresses head and neck cancer cell growth.Feb 01, 2009

Pubmed Data : Arch Otolaryngol Head Neck Surg. 2009 Feb;135(2):190-7. PMID: 19221248
Article Published Date : Feb 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antineoplastic Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Deguelin induces apoptosis by targeting both EGFR-Akt and IGF1R-Akt pathways in head and neck squamous cell cancer cell lines.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:657179. Epub 2015 May 17. PMID: 26075254
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Deguelin
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Apoptotic
[+]

EGCG in combination with cisplatin can be used for the management of head and neck squamous carcinoma cancer stem cells.Sep 30, 2013

Pubmed Data : Eur J Cancer. 2013 Oct ;49(15):3210-8. Epub 2013 Jul 19. PMID: 23876835
Article Published Date : Sep 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways.Sep 06, 2020

Pubmed Data : Apoptosis. 2020 Sep 7. Epub 2020 Sep 7. PMID: 32894380
Article Published Date : Sep 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : Neem
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Essential oil of Cinnamon exhibits significant anticancer activity against head and neck squamous cell carcinoma cells in vitro.Oct 31, 2015

Pubmed Data : J BUON. 2015 Nov-Dec;20(6):1518-25. PMID: 26854449
Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Epidermal growth factor receptor (EGFR) inhibitor
Additional Keywords : Essential Oils
[+]

Ethanolic extract of O. sanctum leaf exerted its anti-invasive effect on head and neck squamous cell carcinoma cells by attenuating MMP activity.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2020 Feb 1 ;21(2):363-370. Epub 2020 Feb 1. PMID: 32102512
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Holy Basil
Diseases : Head and Neck Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Exosomes as immune regulators in head and neck cancer.May 11, 2020

Pubmed Data : HNO. 2020 May 12. Epub 2020 May 12. PMID: 32399644
Article Published Date : May 11, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Head and Neck Cancer
Additional Keywords : Exosomes
[+]

Fucoidan exhibits anticancer properties against head and neck squamous cell carcinoma in vitro.Dec 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Dec 12 ;23(12). Epub 2018 Dec 12. PMID: 30545161
Article Published Date : Dec 11, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Gene targets of sulforaphane in head and neck squamous cell carcinoma.Nov 30, 2019

Pubmed Data : Mol Med Rep. 2019 Dec ;20(6):5335-5344. Epub 2019 Oct 23. PMID: 31661135
Article Published Date : Nov 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Chemopreventive
Additional Keywords : Gene Expression Regulation
[+]

Genistein induced cell cycle G2/M arrest in human salivary adenoid cystic carcinoma cell line SACC-83.Jan 31, 2006

Pubmed Data : Shanghai Kou Qiang Yi Xue. 2006 Feb ;15(1):69-72. PMID: 16525614
Article Published Date : Jan 31, 2006
Study Type : In Vitro Study
Additional Links
Substances : Genistein
Diseases : Head and Neck Cancer, Salivary Gland Adenoid Cystic Carcinoma., Salivary Gland Diseases
Pharmacological Actions : Antiproliferative , Cell cycle arrest, Cyclin D1 Down-Regulation
[+]

Gold nanoparticles enhance X-ray irradiation-induced apoptosis in head and neck squamous cell carcinoma in vitro.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Rep. 2018 Nov ;9(5):415-420. Epub 2018 Aug 22. PMID: 30345038
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gold (nanoparticles)
Diseases : Head and Neck Cancer
Pharmacological Actions : Radiosensitizer
[+]

Grape seed proanthocyanidins, honokiol and EGCG appear to be promising bioactive phytochemicals for the management of head and neck cancer.Nov 23, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 Nov 24 ;21(12). Epub 2016 Nov 24. PMID: 27886147
Article Published Date : Nov 23, 2016
Study Type : Review
Additional Links
Substances : EGCG (Epigallocatechin gallate), Grape Seed Extract, Honokiol, Proanthocyanidins
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Epidermal growth factor receptor (EGFR) inhibitor
[+]

Head and neck radiotherapy may result in radiation-induced changes in the central nervous system and head and neck.Sep 01, 1996

Pubmed Data : Radiographics. 1996 Sep;16(5):1055-72. PMID: 8888390
Article Published Date : Sep 01, 1996
Study Type : Commentary
Additional Links
Diseases : Brain Cancer, Head and Neck Cancer, Head Cancer, Meningioma
Anti Therapeutic Actions : Radiotherapy
[+]

Honey against radiation induced oral mucositis in head and neck cancer patients.Jul 08, 2020

Pubmed Data : Rev Recent Clin Trials. 2020 Jul 9. Epub 2020 Jul 9. PMID: 32646360
Article Published Date : Jul 08, 2020
Study Type : Review
Additional Links
Substances : Honey
Diseases : Head and Neck Cancer, Oral Mucositis
Pharmacological Actions : Radioprotective
[+]

Honokiol inhibits growth and the progression of cancers of different organs.Dec 31, 2015

Pubmed Data : Adv Exp Med Biol. 2016 ;928:245-265. PMID: 27671820
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Bladder Cancer, Breast Cancer, Gastric Cancer, Head and Neck Cancer, Lung Cancer, Melanoma, Neuroblastoma, Prostate Cancer, Skin Cancer: Non-Melanoma
Pharmacological Actions : Antiproliferative , Chemopreventive, Cyclooxygenase 2 Inhibitors, Epidermal growth factor receptor (EGFR) inhibitor
[+]

Honokiol is a promising natural compound in overcoming acquired resistance to cetuximab.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cancer Ther. 2018 Jan ;17(1):204-214. Epub 2017 Oct 20. PMID: 29054984
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Cancers: Drug Resistant, Head and Neck Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
[+]

Induction of sestrin 2 is associated with fisetin-mediated apoptosis in human head and neck cancer cell lines.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2019 Mar ;64(2):97-105. Epub 2018 Oct 13. PMID: 30936621
Article Published Date : Feb 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Head and Neck Cancer
Pharmacological Actions : Apoptotic
[+]

Lactoferricin B reverses cisplatin resistance in head and neck squamous cell carcinoma cells.May 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Med. 2018 May 15. Epub 2018 May 15. PMID: 29761938
Article Published Date : May 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Lactoferrin
Diseases : Cancers: Drug Resistant, Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Anti-Inflammatory Agents, Chemosensitizer, Interleukin-6 Downregulation
[+]

Lactoferrin down-regulates G1 cyclin-dependent kinases during growth arrest of head and neck cancer cells.Dec 14, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cancer Res. 2004 Dec 15 ;10(24):8683-6. PMID: 15623653
Article Published Date : Dec 14, 2004
Study Type : In Vitro Study
Additional Links
Substances : Lactoferrin
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Melatonin could be used as an adjuvant agent with rapamycin in head and neck cancers.Dec 15, 2017

Pubmed Data : J Pineal Res. 2017 Dec 16. Epub 2017 Dec 16. PMID: 29247557
Article Published Date : Dec 15, 2017
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic
Additional Keywords : Chemoprotective Agents, Chemotherapeutic, Head and Neck Cancer, melatonin, Natural Substance/Drug Synergy
[+]

Methylsulfonylmethane induces cell cycle arrest and mitochondrial apoptosis in YD-38 gingival cancer cells.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2017 04 ;37(4):1637-1646. PMID: 28373424
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : MSM (Methylsulfonylmethane)
Diseases : Head and Neck Cancer, Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

N-acetylcysteine inhalation improves the quality of life of patients with head and neck cancers who are receiving radiation therapy.Aug 13, 2020

Pubmed Data : J Cancer Res Clin Oncol. 2020 Aug 14. Epub 2020 Aug 14. PMID: 32803294
Article Published Date : Aug 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Omethoate could induce the pharyngeal cancer cell proliferation.Oct 31, 2019

Pubmed Data : Toxicology. 2019 Nov 1 ;427:152298. Epub 2019 Sep 28. PMID: 31574243
Article Published Date : Oct 31, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Head and Neck Cancer, Pesticide Toxicity , Squamous cell carcinoma
Additional Keywords : Increased Risk
Problem Substances : Organophosphate Pesticides
[+]

Photo-bio-modulation may have a role in supportive care for a broad range of complications associated with the treatment of HNC with CRT.Mar 16, 2016

Pubmed Data : Support Care Cancer. 2016 Mar 17. Epub 2016 Mar 17. PMID: 26984249
Article Published Date : Mar 16, 2016
Study Type : Review
Additional Links
Diseases : Chemotherapy and Radiation Toxicity, Head and Neck Cancer
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic, Radioprotective
[+]

Piperlongumine synergizes with APR-246 to selectively induce apoptosis and autophagic cell death in HNSCC cells.Jan 17, 2018

Pubmed Data : Oncogene. 2018 Jan 18. Epub 2018 Jan 18. PMID: 29348462
Article Published Date : Jan 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Head and Neck Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Selective Cytotoxicity
[+]

Polyphenols have been shown to be effective against multiple targets in cancer development and progression.Dec 31, 2015

Pubmed Data : Nutrients. 2016;8(9). Epub 2016 Sep 9. PMID: 27618095
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Green Tea, Quercetin, Resveratrol
Diseases : Cancers: All, Head and Neck Cancer, Lung Cancer, Ovarian Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Natural Substance Synergy
[+]

Review: Curcumin has therapeutic potential in the treatment of head & neck cancers.Feb 07, 2011

Pubmed Data : Mol Cancer. 2011 Feb 7;10(1):12. Epub 2011 Feb 7. PMID: 21299897
Article Published Date : Feb 07, 2011
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Head and Neck Cancer
[+]

Rosmarinic acid and blue light combination treatment inhibits head and neck squamous cell carcinoma.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2020 Feb ;40(2):751-758. PMID: 32014917
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Head and Neck Cancer
Therapeutic Actions : Light Therapy: Colored
Pharmacological Actions : Antiproliferative
[+]

Sulforaphane has radiosensitizing effects in head and neck cancer cells. Sep 01, 2011

Pubmed Data : Strahlenther Onkol. 2011 Sep ;187(9):575-580. Epub 2011 Aug 16. PMID: 21858418
Article Published Date : Sep 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Head and Neck Cancer
Pharmacological Actions : Anti-Proliferative, Radiosensitizer
[+]

Sweet potato peel could serve as a dietary component to prevent the development of different types of cancer.Oct 31, 2016

Pubmed Data : Nutr Cancer. 2016 Nov-Dec;68(8):1330-1337. Epub 2016 Sep 27. PMID: 27673552
Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Sweet Potato
Diseases : Breast Cancer, Colon Cancer, Head and Neck Cancer, Lung Cancer, Ovarian Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Plant Extracts
[+]

These data suggest that licochalcone-A has potential chemopreventive effects.Feb 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem Toxicol. 2015 Mar ;77:34-43. Epub 2015 Jan 5. PMID: 25572524
Article Published Date : Feb 28, 2015
Study Type : In Vitro Study
Additional Links
Substances : Licorice
Diseases : Head and Neck Cancer, Squamous cell carcinoma
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Plant Extracts
[+]

This review covers the literature that deals with the anticancer mechanism of resveratrol.Dec 20, 2016

Pubmed Data : Crit Rev Food Sci Nutr. 2016 Dec 21:0. Epub 2016 Dec 21. PMID: 28001084
Article Published Date : Dec 20, 2016
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Bladder Cancer, Breast Cancer, Cancers: All, Cervical Cancer, Colon Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancer, Kidney Cancer, Lung Cancer, Ovarian Cancer, Prostate Cancer
Pharmacological Actions : Antioxidants, Chemopreventive
[+]

Thymoquinone is a promising agent in the treatment of head and neck cancer due to its anti-proliferative and radiosensitizing properties.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Jul ;14(1):1147-1151. Epub 2017 May 17. PMID: 28693287
Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Head and Neck Cancer
Pharmacological Actions : Antiproliferative , Radiosensitizer
Additional Keywords : Antiproliferative, Head and Neck Cancer, Radiosensitizer, thymoquinone
[+]

Treatment of HNSCC cells with cafestol leads to a dose-dependent reduction of cell viability and to induction of apoptosis.May 31, 2015

Pubmed Data : Strahlenther Onkol. 2015 Jun ;191(6):511-7. Epub 2015 Jan 10. PMID: 25575980
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cafestol, Coffee
Diseases : Head and Neck Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
Additional Keywords : Dose Response
[+]

Tumor-derived exosomes promote angiogenesis and drive head and neck squamous cell carcinoma progression.Jul 23, 2018

Pubmed Data : Mol Cancer Res. 2018 Jul 24. Epub 2018 Jul 24. PMID: 30042174
Article Published Date : Jul 23, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Head and Neck Cancer
Additional Keywords : Exosomes
[+]

Vitamin A and D have an anti-tumor effect against head and neck squamous cell carcinoma.Dec 01, 2003

Pubmed Data : Auris Nasus Larynx. 2003 Dec;30(4):403-12. PMID: 14656567
Article Published Date : Dec 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Vitamin A, Vitamin D
Diseases : Head and Neck Cancer, Skin Cancer: Squamous Cell
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer
Additional Keywords : Drug: 5-flourouracil
[+]

α- and β-Santalols directly interact with tubulin and cause mitotic arrest and cytotoxicity in oral cancer cells.Jun 25, 2015

Pubmed Data : J Nat Prod. 2015 Jun 26 ;78(6):1357-62. Epub 2015 May 20. PMID: 25993496
Article Published Date : Jun 25, 2015
Study Type : In Vitro Study
Additional Links
Substances : Sandalwood
Diseases : Head and Neck Cancer, Oral Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Essential Oils

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