Heart Failure

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69 Substances Researched for Heart Failure
NameACCKFocus
Coenzyme Q1021177Locked
Vitamin D13127Locked
Chocolate460Locked
Hawthorn744Locked
Arginine533Locked
Citrulline330Locked
Fish Oil230Locked
Astragalus322Locked
Beet220Locked
Carnitine220Locked
Thiamine (B-1) 220Locked
Ubiquinol220Locked
Vitamin C220Locked
D-Ribose314Locked
Testosterone314Locked
Flavonoids313Locked
Curcumin712Locked
Magnesium312Locked
Arjuna110Locked
B-complex110Locked
Fish110Locked
Fruit: All110Locked
Ginseng, unspecified species110Locked
Homeopathic Medicine: All110Locked
Nuts110Locked
Riboflavin (Vitamin B-2)110Locked
Terminalia110Locked
Vegetables: All 110Locked
Vitamin B-6110Locked
Berberine47Locked
Resveratrol35Locked
Asiatic Acid24Locked
Astragaloside34Locked
Ginsenosides24Locked
Puerarin24Locked
Tanshinone IIA34Locked
Gallic Acid23Locked
Ashwagandha12Locked
Bacopa12Locked
Baicalein12Locked
Calcium22Locked
Chlorogenic Acid12Locked
Coriandrum sativum12Locked
Corydalis Yanhusuo12Locked
EGCG (Epigallocatechin gallate)12Locked
Epimedium12Locked
Flaxseed12Locked
Goji12Locked
Green Tea12Locked
Isoflavones12Locked
Luteolin12Locked
Milk Thistle12Locked
Oleuropein12Locked
Omega-3 Fatty Acids12Locked
Paeoniflorin12Locked
Panax Ginseng12Locked
Propolis: Bee12Locked
Protandim12Locked
Pterocarpus marsupium12Locked
Selenium22Locked
Shikonin12Locked
Soy12Locked
Sulforaphane12Locked
Turmeric12Locked
Water: Deep Sea12Locked
phytoestrogens12Locked
Ginseng11Locked
Stilbenes11Locked
Zinc11Locked
25 Problem Substances Researched for Heart Failure
NameACCKFocus
Rosiglitazone (trade name Avandia)560Locked
Angiotensin-Converting Enzyme (ACE) Inhibitor 330Locked
Dextroamphetamine220Locked
Ibuprofen220Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)220Locked
Statin Drugs615Locked
Adderall110Locked
Amphetamine110Locked
Angiotensin Receptor Blockers (ARBs)110Locked
Atorvastatin110Locked
Beta Blockers110Locked
Calcium Channel Antagonists110Locked
Celecoxib110Locked
Diclofenac110Locked
Digoxin110Locked
Fried Foods110Locked
Irbesartan (trade name Avapro)110Locked
Meat110Locked
Metoprolol110Locked
Naproxen110Locked
Rofecoxib110Locked
Lovastatin45Locked
2-chlorobenzylidene malononitrile (CS)13Locked
Fluoride12Locked
Sodium Fluoride12Locked
17 Therapeutic Actions Researched for Heart Failure
NameACCKFocus
Tai Chi340Locked
Yoga340Locked
Dancing230Locked
Exercise627Locked
Thermal Therapy: Far-Infrared423Locked
Sauna Therapy321Locked
Shinrin-yoku (taking in the atmosphere of the forest)220Locked
Biofeedback110Locked
Deep Breathing110Locked
Dietary Modification: Mediterranean Diet110Locked
Hydrotherapy 110Locked
Meditation 110Locked
Music110Locked
Ozone Therapy 110Locked
Therapeutic Breathing110Locked
Light-Emitting Diodes (LEDs) Therapy12Locked
Acupuncture11Locked
1 Problematic Actions Researched for Heart Failure
NameACCKFocus
Angioplasty220Locked
Related Topics

Heart Failure is a Sub of the following Topic

View the Evidence:
219 Abstracts with Heart Failure Research

[+]

Among patients with impaired glucose tolerance or type 2 diabetes, rosiglitazone use for at least 12 months is associated with a significantly increased risk of myocardial infarction and heart failure.Sep 12, 2007

Pubmed Data : JAMA. 2007 Sep 12;298(10):1189-95. PMID: 17848653
Article Published Date : Sep 12, 2007
Study Type : Meta Analysis
Additional Links
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Heart Failure, Myocardial Infarction
Problem Substances : Rosiglitazone (trade name Avandia)
Adverse Pharmacological Actions : Cardiotoxic
[+]

Chocolate consumption in moderation may be associated with a decreased risk of heart failure.Apr 19, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Apr 20 ;9(4). Epub 2017 Apr 20. PMID: 28425931
Article Published Date : Apr 19, 2017
Study Type : Meta Analysis
Additional Links
Substances : Chocolate
Diseases : Heart Failure
Additional Keywords : Risk Reduction
[+]

CoQ(10) may improve the ejection fraction in patients with congestive heart failure.Dec 04, 2012

Pubmed Data : Am J Clin Nutr. 2012 Dec 5. Epub 2012 Dec 5. PMID: 23221577
Article Published Date : Dec 04, 2012
Study Type : Meta Analysis
Additional Links
Substances : Coenzyme Q10
Diseases : Congestive Heart Failure, Heart Failure
Pharmacological Actions : Cardioprotective, Cardiotonic Agents
[+]

Dance therapy may improve peak VO2 and HRQOL in patients with chronic heart failure .May 20, 2014

Pubmed Data : Clin Rehabil. 2014 May 21. Epub 2014 May 21. PMID: 24849796
Article Published Date : May 20, 2014
Study Type : Meta Analysis
Additional Links
Diseases : Congestive Heart Failure: NYHA functional class II, Heart Failure
Therapeutic Actions : Dancing
Pharmacological Actions : Cardioprotective, Cardiotonic Agents
[+]

Effectiveness of Tai Chi for health promotion for adults with health conditions: a scoping review of Meta-analyses.Feb 17, 2020

Pubmed Data : Disabil Rehabil. 2020 Feb 18:1-12. Epub 2020 Feb 18. PMID: 32070137
Article Published Date : Feb 17, 2020
Study Type : Meta Analysis
Additional Links
Diseases : Chronic Obstructive Pulmonary Disease, Coronary Artery Disease, Depression, Heart Failure, Hypertension, Osteoarthritis, Parkinson's Disease
Additional Keywords : Risk Reduction
[+]

Patients with heart failure who used coenzyme Q10 had lower mortality and a higher exercise capacity improvement than the placebo.Jul 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cardiovasc Disord. 2017 Jul 24 ;17(1):196. Epub 2017 Jul 24. PMID: 28738783
Article Published Date : Jul 23, 2017
Study Type : Meta Analysis
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Cardiovascular Agents
[+]

Supplementation of fish oil may reduce the circulating levels of TNF-α, IL-1 and IL-6 in patients with chronic heart failure.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cardiovasc Disord. 2012 ;12:77. Epub 2012 Sep 20. PMID: 22994912
Article Published Date : Dec 31, 2011
Study Type : Meta Analysis
Additional Links
Substances : Fish Oil
Diseases : C-Reactive Protein, Heart Failure, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tai Chi was beneficial for chronic conditions-cancer, osteoarthritis, heart failure and chronic obstructive pulmonary disease. Sep 16, 2015

Pubmed Data : Br J Sports Med. 2015 Sep 17. Epub 2015 Sep 17. PMID: 26383108
Article Published Date : Sep 16, 2015
Study Type : Meta Analysis, Review
Additional Links
Diseases : Cancers: All, Chronic Obstructive Pulmonary Disease, Heart Failure, Osteoarthritis
Therapeutic Actions : Tai Chi
[+]

The pooled results showed a 19% relative risk reduction of heart failure incidence with higher chocolate consumption.Jan 27, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab Cardiovasc Dis. 2016 Jan 28. Epub 2016 Jan 28. PMID: 27052923
Article Published Date : Jan 27, 2016
Study Type : Meta Analysis
Additional Links
Substances : Chocolate
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]

The results showed that high dose vitamin D treatment could potentially benefit adults with chronic heart failure.Apr 15, 2019

Pubmed Data : Int J Vitam Nutr Res. 2019 Apr 16:1-10. Epub 2019 Apr 16. PMID: 30987550
Article Published Date : Apr 15, 2019
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Heart Failure, Vitamin D Deficiency
[+]

Vitamin D supplementation may decrease serum levels of parathyroid hormone and inflammatory mediators in patients with chronic heart failure.Sep 27, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cardiol. 2015 Sep 28. Epub 2015 Sep 28. PMID: 26415519
Article Published Date : Sep 27, 2015
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : C-Reactive Protein, Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Parathyroid Hormone
[+]

Vitamin D supplementation might protect against cardiac failure in older people but does not appear to protect against MI or stroke.Aug 31, 2014

Pubmed Data : Am J Clin Nutr. 2014 Sep ;100(3):746-55. Epub 2014 Jul 23. PMID: 25057156
Article Published Date : Aug 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Vitamin D
Diseases : Heart Failure, Vitamin D Deficiency
Pharmacological Actions : Cardiovascular Agents
Additional Keywords : Risk Reduction, Significant Treatment Outcome
[+]

Yoga has a positive effect on patients witih chronic heart failure. Oct 09, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arq Bras Cardiol. 2014 Oct 10 ;0. Epub 2014 Oct 10. PMID: 25317861
Article Published Date : Oct 09, 2014
Study Type : Meta Analysis
Additional Links
Diseases : Congestive Heart Failure, Congestive Heart Failure: NYHA functional class II, Heart Failure
Therapeutic Actions : Yoga
Pharmacological Actions : Cardioprotective, Cardiotonic Agents
[+]

"Vitamin D deficiency is a predictor of reduced survival in patients with heart failure; vitamin D supplementation improves outcome."Feb 03, 2012

Pubmed Data : Eur J Heart Fail. 2012 Feb 3. Epub 2012 Feb 3. PMID: 22308011
Article Published Date : Feb 03, 2012
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Congestive Heart Failure, Heart Failure
[+]

A causual relationship between dextroamphetamine use and cardiomyopathy has been reported.Jun 01, 1976

Pubmed Data : Am Heart J. 1976 Jun;91(6):792-7. PMID: 132114
Article Published Date : Jun 01, 1976
Study Type : Human Study
Additional Links
Diseases : Cardiomyopathy, Heart Failure
Problem Substances : Dextroamphetamine
[+]

A combination of heart rate variability (HRV) biofeedback and breathing retraining has the potential to improve cardiac mortality and morbidity in heart failure patients.Jun 01, 2009

Pubmed Data : Appl Psychophysiol Biofeedback. 2009 Jun;34(2):71-91. Epub 2009 Feb 10. PMID: 19205870
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Biofeedback, Therapeutic Breathing
[+]

A high dihomo-gamma-linoleic acid/arachidonic acid ratio and high DGLA levels, but not AA levels, are associated with a better prognosis in patients with acute cardiovascular disease.Aug 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lipids Health Dis. 2017 Aug 14 ;16(1):150. Epub 2017 Aug 14. PMID: 28806965
Article Published Date : Aug 14, 2017
Study Type : Human Study
Additional Links
Substances : Arachidonic Acid, Essential Fatty Acids, Omega-3 Fatty Acids, Omega-6 Fatty Acids
Diseases : Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective
Additional Keywords : Cardiovascular Diseases, heart disease, Inflammation
[+]

A large randomized trial following 4100+ men and women with heart failure and normal ejection fraction (>=45%) over 4+ years found no improvement in study outcomes or survival with irbesartan as compared to placebo.Dec 04, 2008

Pubmed Data : N Engl J Med. 2008 Dec 4;359(23):2456-67. Epub 2008 Nov 11. PMID: 19001508
Article Published Date : Dec 04, 2008
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Heart Failure, Hypertension
Additional Keywords : Drugs that are no Better than Placebo
Problem Substances : Angiotensin-Converting Enzyme (ACE) Inhibitor , Irbesartan (trade name Avapro)
[+]

A low plasma vitamin D concentration was strongly associated with atrial fibrillation in patients with chronic heart failure.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Clin Exp Med. 2016 Jul-Aug;25(1):51-7. PMID: 26935498
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Atrial Fibrillation, Heart Failure, Vitamin D Deficiency
[+]

ACE Inhibitors/Angiotensin II type 1 receptor antagonists do not reduce hospitalisations in older patients with heart failure. Jan 01, 2007

Pubmed Data : Drugs Aging. 2007;24(11):945-55. PMID: 17953461
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Problem Substances : Angiotensin-Converting Enzyme (ACE) Inhibitor , Angiotensin Receptor Blockers (ARBs)
[+]

Adderrall use has been linked to cardiomyopathy and heart failure.May 01, 2008

Pubmed Data : Am J Ther. 2008 May-Jun;15(3):287-9. PMID: 18496266
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Diseases : Cardiomyopathy, Heart Failure
Problem Substances : Adderall, Amphetamine, Dextroamphetamine
Adverse Pharmacological Actions : Cardiotoxic
[+]

Additive benefits of twice forest bathing trips in elderly patients with chronic heart failure.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Environ Sci. 2018 Feb ;31(2):159-162. PMID: 29606196
Article Published Date : Jan 31, 2018
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Heart Failure
Therapeutic Actions : Shinrin-yoku (taking in the atmosphere of the forest)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

Administration of L-arginine and citrulline to patients improve the condition of heart failure patients with preserved ejection fraction.Jan 01, 2010

Pubmed Data : Cardiol J. 2010;17(6):612-8. PMID: 21154265
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Arginine, Citrulline
Diseases : Heart Failure, Hypertension
Pharmacological Actions : Cardiotonic Agents
[+]

Astragalus has a significant effect on improving heart function in patients with congestive heart failure.Oct 01, 2001

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 Oct;21(10):747-9. PMID: 12575607
Article Published Date : Oct 01, 2001
Study Type : Human Study
Additional Links
Substances : Astragalus
Diseases : Heart Failure
[+]

Astragalus improves cardiac function in aged patients with Chronic Heart Failure.Sep 01, 2005

Pubmed Data : Chin J Integr Med. 2005 Sep;11(3):187-90. PMID: 16181532
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Astragalus
Diseases : Heart Failure
Pharmacological Actions : Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Atorvastatin worsens left ventricular diastolic function, which is improved through coenzyme q10 supplementation. Nov 15, 2004

Pubmed Data : Am J Cardiol. 2004 Nov 15 ;94(10):1306-10. PMID: 15541254
Article Published Date : Nov 15, 2004
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Coenzyme Q10 Deficiency, Heart Failure, Hypertension, Statin-Induced Pathologies
Pharmacological Actions : Anticholesteremic Agents, Antioxidants
Problem Substances : Atorvastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic
[+]

Baked/boiled fish reduces heart failure risk in postmenopausal women whereas fried fish increases it. Jul 01, 2011

Pubmed Data : Circ Heart Fail. 2011 Jul 1 ;4(4):404-13. Epub 2011 May 24. PMID: 21610249
Article Published Date : Jul 01, 2011
Study Type : Human Study
Additional Links
Substances : Fish
Diseases : Heart Failure
Problem Substances : Fried Foods
[+]

Baseline vitamin D levels below 55-65 nmol/L are predictive of all-cause mortality, CVD death and heart failure.Sep 25, 2017

Pubmed Data : Clin Endocrinol (Oxf). 2017 Sep 26. Epub 2017 Sep 26. PMID: 28949411
Article Published Date : Sep 25, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : All-Cause Mortality, Cardiac Mortality , Heart Failure, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Better adherence to a Mediterranean diet was associated with lower risk of myocardial Infarction, heart Failure and ischemic stroke.Sep 02, 2015

Pubmed Data : Atherosclerosis. 2015 Sep 3 ;243(1):93-98. Epub 2015 Sep 3. PMID: 26363438
Article Published Date : Sep 02, 2015
Study Type : Human Study
Additional Links
Diseases : Heart Failure, Myocardial Infarction, Stroke
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Additional Keywords : Risk Reduction
[+]

Both tai chi and resistance band groups saw reduced depression symptoms compared with treatment as usual.Aug 06, 2019

Pubmed Data : J Cardiopulm Rehabil Prev. 2019 Aug 7. Epub 2019 Aug 7. PMID: 31397771
Article Published Date : Aug 06, 2019
Study Type : Human Study
Additional Links
Diseases : Depression, Heart Failure
Therapeutic Actions : Exercise: Resistance Training, Tai Chi
Pharmacological Actions : Antidepressive Agents
[+]

Cardiac complications are common after liver transplantation.Mar 15, 2009

Pubmed Data : Transplantation. 2009 Mar 15 ;87(5):763-70. PMID: 19295324
Article Published Date : Mar 15, 2009
Study Type : Human Study
Additional Links
Diseases : Cardiac Arrhythmias, Heart Failure, Organ Transplantation: Liver, Pulmonary Edema
Additional Keywords : Diseases that are Linked
[+]

Chan-Chuang qigong improves exercise capacity, depression, and quality of life in patients with heart failure.Sep 30, 2018

Pubmed Data : Hu Li Za Zhi. 2018 Oct ;65(5):34-44. PMID: 30276771
Article Published Date : Sep 30, 2018
Study Type : Human Study
Additional Links
Diseases : Depression, Heart Failure
Therapeutic Actions : Qigong
Pharmacological Actions : Antidepressive Agents
[+]

Chocolate consumption was associated with lower cardiac mortality in a dose dependent manner in patients free of diabetes surviving their first heart attack.Sep 01, 2009

Pubmed Data : J Intern Med. 2009 Sep;266(3):248-57. PMID: 19711504
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cardiac Mortality , Cardiovascular Diseases, Heart Failure, Myocardial Infarction
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]

Chronic L-arginine supplementation enhances endurance exercise tolerance in heart failure patients.Jul 01, 2006

Pubmed Data : Int J Sports Med. 2006 Jul;27(7):567-72. PMID: 16802253
Article Published Date : Jul 01, 2006
Study Type : Human Study
Additional Links
Substances : Arginine
Diseases : Heart Failure
[+]

Coenzyme q10 appears to prevent tachycardia in heart failure patientsJan 01, 2008

Pubmed Data : Biofactors. 2008;32(1-4):145-9. PMID: 19096110
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure, Tachycardia
[+]

Coenzyme Q10 as an adjuvant in conventional therapy for heart failure reduces hospitalization and incidence of serious complications. Jan 01, 1993

Pubmed Data : Clin Investig. 1993;71(8 Suppl):S134-6. PMID: 8241697
Article Published Date : Jan 01, 1993
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Congestive Heart Failure, Heart Failure
[+]

Coenzyme Q10 improves ejection fraction as an adjunctive therapy for congestive heart failure. Oct 30, 2009

Pubmed Data : N Z Med J. 2009 Oct 30;122(1305):74-9. PMID: 19966871
Article Published Date : Oct 30, 2009
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Congestive Heart Failure, Heart Dysfunction: Ejection Fraction, Low, Heart Failure
Additional Keywords : Statin Intervention has not Improved Outcomes in Congestive Heart Failure
[+]

CoenzymeQ10 as adjuvant treatment in patients with heart failure may attenuate the incidence of atrial fibrillation.May 31, 2015

Pubmed Data : J Investig Med. 2015 Jun ;63(5):735-9. PMID: 25919281
Article Published Date : May 31, 2015
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Atrial Fibrillation, Heart Failure
Pharmacological Actions : Cardioprotective, Malondialdehyde Down-regulation
Additional Keywords : Significant Treatment Outcome
[+]

Coq10 is safe and efficacious as an adjunctive therapy in heart failure. Apr 01, 2005

Pubmed Data : Forsch Komplementarmed Klass Naturheilkd. 2005 Apr;12(2):77-83. PMID: 8241700
Article Published Date : Apr 01, 2005
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
[+]

Coq10 used as an adjunctive therapy in heart failure improves clinical signs and symptoms in the majority of patients tested. Jan 01, 1994

Pubmed Data : Mol Aspects Med. 1994;15 Suppl:s287-94. PMID: 7752841
Article Published Date : Jan 01, 1994
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Cardiovascular Agents
[+]

Coronary intervention for persistent occlusion after myocardial infarction. does not reduce the occurrence of death, reinfarction, or heart failure, and there was a trend toward excess reinfarction during 4 years of follow-up in stable patients with occluDec 07, 2006

Pubmed Data : N Engl J Med. 2006 Dec 7;355(23):2395-407. Epub 2006 Nov 14. PMID: 17105759
Article Published Date : Dec 07, 2006
Study Type : Human Study
Additional Links
Diseases : Angioplasty, Cardiac Mortality , Heart Failure, Myocardial Infarction
Anti Therapeutic Actions : Angioplasty
[+]

D-ribose aids congestive heart failure patients.Apr 30, 1992

Pubmed Data : Cancer Lett. 1992 Apr 30;63(3):237-41. PMID: 14607200
Article Published Date : Apr 30, 1992
Study Type : Human Study
Additional Links
Substances : D-Ribose
Diseases : Congestive Heart Failure, Coronary Artery Disease, Heart Failure
[+]

Deep breathing suppresses steady-state sympathetic nerve activity in patients with high levels of resting sympathetic tone as in heart failure.Oct 14, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Physiol Heart Circ Physiol. 2014 Oct 15 ;307(8):H1159-68. Epub 2014 Aug 15. PMID: 25128165
Article Published Date : Oct 14, 2014
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Deep Breathing
[+]

Dietary nitrate supplementation opposes the elevated diaphragm blood flow in chronic heart failure during submaximal exercise.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Respir Physiol Neurobiol. 2018 01 ;247:140-145. Epub 2017 Oct 14. PMID: 29037770
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Beet
Diseases : Heart Failure
Therapeutic Actions : Exercise
[+]

Digoxin use was independently associated with significantly higher risk of death and a higher risk of hospitalization. Nov 19, 2014

Pubmed Data : Circ Arrhythm Electrophysiol. 2014 Nov 20. Epub 2014 Nov 20. PMID: 25414270
Article Published Date : Nov 19, 2014
Study Type : Human Study
Additional Links
Diseases : Atrial Fibrillation, Heart Failure
Additional Keywords : Morbidity, Mortality
Problem Substances : Digoxin
[+]

Evidence shows a strong association between vitamin D deficiency and increased risk of heart failure in elderly populations.Aug 16, 2017

Pubmed Data : ESC Heart Fail. 2017 Aug 17. Epub 2017 Aug 17. PMID: 28817241
Article Published Date : Aug 16, 2017
Study Type : Human Study
Additional Links
Diseases : Heart Failure, Vitamin D Deficiency
Additional Keywords : Increased Risk
[+]

Exercise programs had positive effects in reducing the severity of depression in heart failure patients.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2019 Aug ;98(32):e16820. PMID: 31393414
Article Published Date : Jul 31, 2019
Study Type : Human Study
Additional Links
Diseases : Depression, Heart Failure
Therapeutic Actions : Exercise
Pharmacological Actions : Antidepressive Agents
[+]

Fish intake (excluding fried fish) reduces the risk of heart failure. Jun 21, 2005

Pubmed Data : J Am Coll Cardiol. 2005 Jun 21;45(12):2015-21. PMID: 15963403
Article Published Date : Jun 21, 2005
Study Type : Human Study
Additional Links
Substances : Fish Oil
Diseases : Heart Failure
Additional Keywords : Risk Reduction
[+]

Flavanol-rich chocolate acutely improves vascular function in patients with congestive heart failure.Aug 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Heart J. 2012 Sep ;33(17):2172-80. Epub 2011 Dec 15. PMID: 22173910
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Chocolate
Diseases : Endothelial Dysfunction, Heart Failure, Oxidative Stress
Pharmacological Actions : Cardioprotective
[+]

Following 3-month astaxanthin supplementation, suppressed oxidative stress and improved cardiac contractility and exercise tolerance.Jun 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jun 26 ;12(6). Epub 2020 Jun 26. PMID: 32604721
Article Published Date : Jun 25, 2020
Study Type : Human Study
Additional Links
Substances : Astaxanthin
Diseases : Heart Failure
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Ginseng improves the condition of patients with congestive heart failure and raises levels of T3 and T4. Apr 01, 1999

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Apr;19(4):209-11. PMID: 11783267
Article Published Date : Apr 01, 1999
Study Type : Human Study
Additional Links
Substances : Ginseng, unspecified species
Diseases : Congestive Heart Failure, Heart Failure, Hypothyroidism
[+]

Hawthorn (Crataegus) reduces the incidence of sudden cardiac death in patients with less compromised left ventricular function.Dec 01, 2008

Pubmed Data : Eur J Heart Fail. 2008 Dec;10(12):1255-63. Epub 2008 Nov 18. PMID: 19019730
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Hawthorn
Diseases : Heart Failure, Left Ventricular Dysfunction
Additional Keywords : Plant Extracts, Risk Reduction
[+]

Hawthorn berry extract is safe and effective in improving exercise tolerance and quality of life in patients with congestive heart failure Oct 01, 2001

Pubmed Data : Arzneimittelforschung. 2001 Oct;51(10):793-8. PMID: 11715631
Article Published Date : Oct 01, 2001
Study Type : Human Study
Additional Links
Substances : Hawthorn
Diseases : Congestive Heart Failure, Heart Failure
[+]

Hawthorn provides benefits as an adjunctive treatment for chronic heart failure. - Article 1Jun 01, 2003

Pubmed Data : Am J Med. 2003 Jun 1;114(8):665-74. PMID: 12798455
Article Published Date : Jun 01, 2003
Study Type : Human Study
Additional Links
Substances : Hawthorn
Diseases : Heart Failure
[+]

Hawthorn provides benefits as an adjunctive treatment for chronic heart failure. - Article 2Jan 23, 2008

Pubmed Data : Cochrane Database Syst Rev. 2008 Jan 23;(1):CD005312. PMID: 18254076
Article Published Date : Jan 23, 2008
Study Type : Human Study
Additional Links
Substances : Hawthorn
Diseases : Heart Failure
[+]

Heart failure patients have high rates of B-vitamin deficiency. Aug 01, 2009

Pubmed Data : J Am Diet Assoc. 2009 Aug;109(8):1406-10. PMID: 19631047
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Substances : B-complex, Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-6
Diseases : Heart Failure
[+]

Ibuprofen use may increase the risk of thrombotic and congestive heart failure events.Jun 01, 2007

Pubmed Data : Ann Rheum Dis. 2007 Jun;66(6):764-70. Epub 2007 Apr 5. PMID: 17412741
Article Published Date : Jun 01, 2007
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Congestive Heart Failure, Heart Attack, Heart Failure, Thrombosis
Problem Substances : Ibuprofen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Cardiotoxic
[+]

Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation.Dec 31, 2011

Pubmed Data : Cardiol J. 2012 ;19(6):612-7. PMID: 23224924
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Citrulline
Diseases : Heart Failure, Left Ventricular Dysfunction
[+]

L-carnitine is a useful therapeutic agent for the treatment of congestive heart failure in combination with traditional pharmacological therapy.Jan 01, 1992

Pubmed Data : Jpn Circ J. 1992 Jan;56(1):86-94. PMID: 1538579
Article Published Date : Jan 01, 1992
Study Type : Human Study
Additional Links
Substances : Carnitine
Diseases : Congestive Heart Failure, Heart Failure
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Long-term coenzyme Q10 therapy has significant therapeutic effects in patients with advanced heart failture.Aug 01, 2005

Pubmed Data : Wien Klin Wochenschr. 2005 Aug;117(15-16):558-60. PMID: 3836876
Article Published Date : Aug 01, 2005
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
[+]

Long-term CoQ10 treatment of patients with chronic heart failure is safe, improves symptoms, and reduces major adverse cardiovascular events.Nov 30, 2014

Pubmed Data : JACC Heart Fail. 2014 Dec ;2(6):641-9. Epub 2014 Oct 1. PMID: 25282031
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]

Low free testosterone is associated with heart failure mortality in older men.May 01, 2011

Pubmed Data : Eur J Heart Fail. 2011 May;13(5):482-8. Epub 2011 Feb 20. PMID: 21339189
Article Published Date : May 01, 2011
Study Type : Human Study
Additional Links
Substances : Testosterone
Diseases : Elderly: Age Specific Diseases, Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Magnesium supplementation is beneficial to patients with symptomatic heart failure. Aug 01, 1996

Pubmed Data : J Periodontal Res. 1996 Aug;31(6):408-13. PMID: 16470086
Article Published Date : Aug 01, 1996
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Endothelial Dysfunction, Heart Failure
[+]

Meditation reduced norepinephrine blood levels, quality of life and cardiopulmonary function in elderly patients with optimally treated congestive heart failure. Oct 09, 2009

Pubmed Data : Food Chem Toxicol. 2009 Oct 9. PMID: 15992231
Article Published Date : Oct 09, 2009
Study Type : Human Study
Additional Links
Diseases : Congestive Heart Failure, Heart Failure, Quality of Life: Poor
Therapeutic Actions : Meditation
[+]

Moderate chocolate consumption was associated with a lower rate of heart failure hospitalization or death.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am Heart J. 2017 Jan ;183:18-23. Epub 2016 Oct 6. PMID: 27979037
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Chocolate
Diseases : Cardiac Mortality , Heart Failure
Additional Keywords : Cardiac Mortality, chocolate, Heart Failure, men's health, Risk Reduction
[+]

Moderate consumption of chocolate might be associated with a lower risk of heart failure in male physicians.Nov 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Heart Fail. 2014 Dec ;16(12):1372-6. Epub 2014 Oct 14. PMID: 25311633
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Music therapy decreased congestive heart failure in elderly patients by reducing plasma cytokine and catecholamine levels.Jan 01, 2009

Pubmed Data : Int Heart J. 2009 Jan;50(1):95-110. PMID: 19246850
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Congestive Heart Failure, Elderly: Age Specific Diseases, Heart Failure
Therapeutic Actions : Music
Pharmacological Actions : Interleukin-6 Downregulation
[+]

NSAIDs are frequently used in patients with heart failure and are associated with increased risk of death and cardiovascular morbidity.Jan 26, 2009

Pubmed Data : Arch Intern Med. 2009 Jan 26;169(2):141-9. PMID: 19171810
Article Published Date : Jan 26, 2009
Study Type : Human Study
Additional Links
Diseases : Heart Failure, Myocardial Infarction
Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib
[+]

Nut consumption may play a role in reducing the risk of atrial fibrillation and possibly heart failure.Apr 15, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heart. 2018 Apr 16. Epub 2018 Apr 16. PMID: 29661934
Article Published Date : Apr 15, 2018
Study Type : Human Study
Additional Links
Substances : Nuts
Diseases : Atrial Fibrillation, Cardiovascular Diseases, Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]

One week of daily beetroot juice significantly improves submaximal aerobic endurance and blood pressure in elderly HFpEF patients.Feb 01, 2016

Pubmed Data : JACC Heart Fail. 2016 Feb 2. Epub 2016 Feb 2. PMID: 26874390
Article Published Date : Feb 01, 2016
Study Type : Human Study
Additional Links
Substances : Beet
Diseases : Heart Failure, Hypertension
Therapeutic Actions : Exercise
Pharmacological Actions : Antihypertensive Agents
[+]

Ozone therapy might be beneficial in terms of activating antioxidant system and merit further therapeutic potential to conventional heart failure treatment.Sep 30, 2017

Pubmed Data : Cardiovasc Toxicol. 2017 Oct ;17(4):426-433. PMID: 28097518
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants
[+]

Patients with chronic heart failure have increased intestinal permeability and an augmented bacterial biofilm contributing to both chronic inflammation and malnutrition. Oct 16, 2007

Pubmed Data : J Am Coll Cardiol. 2007 Oct 16;50(16):1561-9. Epub 2007 Oct 1. PMID: 17936155
Article Published Date : Oct 16, 2007
Study Type : Human Study
Additional Links
Diseases : Bacterial Infections: Resistance/Biofilm Formation, Heart Failure, Leaky Gut Syndrome
Additional Keywords : Diseases that are Linked
[+]

Patients with cogestive heart failure have high rates of thiamine deficiency. Jan 17, 2006

Pubmed Data : J Am Coll Cardiol. 2006 Jan 17;47(2):354-61. PMID: 16412860
Article Published Date : Jan 17, 2006
Study Type : Human Study
Additional Links
Substances : Thiamine (B-1)
Diseases : Heart Failure
[+]

Patients with hypertension treated with calcium channel blockers have increased incident of heart failure.Jul 15, 2010

Pubmed Data : Am J Cardiol. 2010 Jul 15;106(2):228-35. PMID: 20599008
Article Published Date : Jul 15, 2010
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Heart Failure, Hypertension
Problem Substances : Calcium Channel Antagonists
Adverse Pharmacological Actions : Cardiotoxic
[+]

Plasma vitamin C, a biomarker reflecting fruit and vegetable intake, was inversely associated with the risk of heart failure.Aug 01, 2011

Pubmed Data : Am Heart J. 2011 Aug ;162(2):246-53. Epub 2011 Jul 7. PMID: 21835284
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All , Vitamin C
Diseases : Heart Failure
[+]

Processed red meat consumption is associated with an increased risk of heart failure in men. Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Circ Heart Fail. 2014 Jul ;7(4):552-7. Epub 2014 Jun 12. PMID: 24926039
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Additional Keywords : Increased Risk
Problem Substances : Meat
[+]

Pycnogenol® in combination with coenzymeQ10 may be of value in heart failure patients.May 31, 2010

Pubmed Data : Panminerva Med. 2010 Jun ;52(2 Suppl 1):21-5. PMID: 20657530
Article Published Date : May 31, 2010
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure, Hypertension
[+]

Relationship between urinary bisphenol a levels and cardiovascular diseases in the U.S. adult population.Feb 09, 2020

Pubmed Data : Ecotoxicol Environ Saf. 2020 Feb 10 ;192:110300. Epub 2020 Feb 10. PMID: 32058166
Article Published Date : Feb 09, 2020
Study Type : Human Study
Additional Links
Diseases : Angina Pectoris, Bisphenol Toxicity, Cardiovascular Diseases, Heart Failure, Myocardial Infarction
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Cardiotoxic
[+]

Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure.Mar 06, 2002

Pubmed Data : J Am Coll Cardiol. 2002 Mar 6;39(5):754-9. PMID: 11869837
Article Published Date : Mar 06, 2002
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Sauna Therapy
[+]

Repeated sauna treatment improves ventricular arrhythmias in patients with chronic heart failure.Dec 01, 2004

Pubmed Data : Circ J. 2004 Dec;68(12):1146-51. PMID: 15564698
Article Published Date : Dec 01, 2004
Study Type : Human Study
Additional Links
Diseases : Arrhythmias: Cardiac, Heart Failure
Therapeutic Actions : Sauna Therapy
[+]

Rosiglitazone use is associated with an increased risk of acute myocardial infarction in the elderly.Apr 01, 2009

Pubmed Data : Diab Vasc Dis Res. 2009 Apr;6(2):87-93. PMID: 20368198
Article Published Date : Apr 01, 2009
Study Type : Human Study
Additional Links
Diseases : Elderly: Age Specific Diseases, Heart Failure, Myocardial Infarction
Problem Substances : Rosiglitazone (trade name Avandia)
Adverse Pharmacological Actions : Cardiotoxic
[+]

Rosiglitazone use is associated with an increased risk of stroke, heart failure, and all-cause mortality.Jul 28, 2010

Pubmed Data : JAMA. 2010 Jul 28;304(4):411-8. Epub 2010 Jun 28. PMID: 20584880
Article Published Date : Jul 28, 2010
Study Type : Human Study
Additional Links
Diseases : Cardiac Mortality , Diabetes Mellitus: Type 2, Heart Failure, Mortality: All-Cause, Myocardial Infarction, Stroke
Problem Substances : Rosiglitazone (trade name Avandia)
Adverse Pharmacological Actions : Cardiotoxic
[+]

Six months of vitamin D supplementation significantly improves ejection fraction in elderly patients with heart failure and vitamin D deficiency.Jul 31, 2014

Pubmed Data : Nutr Metab Cardiovasc Dis. 2014 Aug ;24(8):861-8. Epub 2014 Mar 5. PMID: 24787908
Article Published Date : Jul 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Heart Failure, Hypertension, Vitamin D Deficiency
Pharmacological Actions : Antihypertensive Agents
[+]

Supplemental ubiquinol has therapeutic effects in advanced congestive heart failure patients.Jan 01, 2008

Pubmed Data : Biofactors. 2008;32(1-4):119-28. PMID: 19096107
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Ubiquinol
Diseases : Congestive Heart Failure, Heart Failure
Pharmacological Actions : Cardiotonic Agents
[+]

Tai Chi may enhance quality of life, exercise capacity and sleep stability in patients with chronic heart failure. Jan 01, 2008

Pubmed Data : Med Sport Sci. 2008;52:195-208. PMID: 18487899
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Tai Chi
Additional Keywords : Chronic Heart Failure
[+]

Tai Chi training is safe and produces significant improvements in symptoms and quality of life in patients with symptomatic heart failure. Nov 01, 2007

Pubmed Data : Postgrad Med J. 2007 Nov;83(985):717-21. PMID: 17989272
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Tai Chi
[+]

Terminalia arjuna contributes to improvement of patients with refractory chronic congestive heart failure.May 01, 1995

Pubmed Data : Int J Cardiol. 1995 May;49(3):191-9. PMID: 7649665
Article Published Date : May 01, 1995
Study Type : Human Study
Additional Links
Substances : Arjuna, Terminalia
Diseases : Heart Failure
[+]

The administration of CoQ10 to heart transplant candidates led to a significant improvement in functional status, clinical symptoms, and quality of life. May 01, 2004

Pubmed Data : Clin Cardiol. 2004 May;27(5):295-9. PMID: 15188947
Article Published Date : May 01, 2004
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The administration of L-arginine and citrulline has a beneficial effect on endothelial function in the treatment of heart failure.Jan 01, 2010

Pubmed Data : Cardiol J. 2010;17(5):464-70. PMID: 20865676
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Arginine, Citrulline
Diseases : Endothelial Dysfunction, Heart Failure
[+]

The beneficial effects of Mediterranean diet adherence and congestive heart failure.Sep 12, 2019

Pubmed Data : Nutrition. 2019 Sep 13 ;70:110584. Epub 2019 Sep 13. PMID: 31759318
Article Published Date : Sep 12, 2019
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Cardioprotective
[+]

The beta blocker metoprolol is associated with an increased risk for the onset of diabetes in patients with heart failure. Aug 01, 2007

Pubmed Data : Heart. 2007 Aug;93(8):968-73. Epub 2007 Jan 19. PMID: 17237130
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Problem Substances : Beta Blockers, Metoprolol
[+]

The effect of dietary inorganic nitrate supplementation on cardiac function during submaximal exercise in men with heart failure.Jul 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jul 17 ;12(7). Epub 2020 Jul 17. PMID: 32709051
Article Published Date : Jul 16, 2020
Study Type : Human Study
Additional Links
Substances : Beet
Diseases : Heart Failure
Therapeutic Actions : Exercise
Pharmacological Actions : Cardioprotective
[+]

The homeopathic crataegus preparation cralonin is as good as conventional treatments for mild cardiac insufficiency.May 31, 2003

Pubmed Data : Eur J Heart Fail. 2003 Jun ;5(3):319-26. PMID: 12798830
Article Published Date : May 31, 2003
Study Type : Human Study
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Coronary Artery Disease, Heart Failure, Hypertension
Additional Keywords : Homeopathic Vs. Conventional Treatment, Phytotherapy, Significant Treatment Outcome
Problem Substances : Angiotensin-Converting Enzyme (ACE) Inhibitor
[+]

The use of rosiglitazone (Avandia) in type 2 diabetic patients is associated with an increased risk of heart failure and of some fractures, mainly in women. Jun 20, 2009

Pubmed Data : Lancet. 2009 Jun 20;373(9681):2125-35. Epub 2009 Jun 6. PMID: 19501900
Article Published Date : Jun 20, 2009
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Heart Failure, Myocardial Infarction, Osteoporosis
Additional Keywords : Drug: Metformin
Problem Substances : Rosiglitazone (trade name Avandia)
[+]

The use of rosiglitazone (Avandia) in type 2 diabetic patients is associated with increased risk of heart failure. Jan 29, 2010

Pubmed Data : Eur Heart J. 2010 Jan 29. Epub 2010 Jan 29. PMID: 20118174
Article Published Date : Jan 29, 2010
Study Type : Human Study
Additional Links
Diseases : Cardiac Mortality , Diabetes: Cardiovascular Illness, Heart Failure
Problem Substances : Rosiglitazone (trade name Avandia)
[+]

There is a lack of benefit with percutaneous intervention for late persistent occlusion after myocardial infarction.Jan 01, 2008

Pubmed Data : J Cardiovasc Nurs. 2008 Jan-Feb;23(1):30-3. PMID: 18158504
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Angioplasty, Heart Failure, Myocardial Infarction
Anti Therapeutic Actions : Angioplasty
[+]

These results provided direct evidence that forest bathing has a beneficial effect on chronic heart failure patients.Mar 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2017 Mar 31 ;14(4). Epub 2017 Mar 31. PMID: 28362327
Article Published Date : Mar 30, 2017
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Shinrin-yoku (taking in the atmosphere of the forest)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Ubiquinol + L-carnitine can cause a significant reduction in the pro-inflammatory cytokines in patients with heart failure.Aug 01, 2007

Pubmed Data : Acta Cardiol. 2007 Aug;62(4):349-54. PMID: 17824295
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Substances : Carnitine, Coenzyme Q10, Ubiquinol
Diseases : Heart Failure
Pharmacological Actions : Interleukin-6 Downregulation
[+]

Ubiquinol improves endothelial function in patients with heart failure with reduced ejection fraction.Nov 11, 2019

Pubmed Data : Am J Cardiovasc Drugs. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31713723
Article Published Date : Nov 11, 2019
Study Type : Human Study
Additional Links
Substances : Ubiquinol
Diseases : Endothelial Dysfunction, Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Vitamin C deficiency moderated the relationship between inflammation and cardiac event risks in patients with heart failure.Dec 14, 2016

Pubmed Data : J Cardiovasc Nurs. 2016 Dec 15. Epub 2016 Dec 15. PMID: 27984333
Article Published Date : Dec 14, 2016
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Heart Failure, Inflammation, Vitamin C Deficiency
Additional Keywords : Risk Factors
[+]

Vitamin C inhibits endothelial cell apoptosis in congestive heart failure.Oct 29, 2001

Pubmed Data : Circulation. 2001 Oct 30 ;104(18):2182-7. PMID: 11684628
Article Published Date : Oct 29, 2001
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Endothelial Dysfunction, Heart Failure, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Enzyme Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin D deficiency has a significant impact in heart failure patients.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dis Markers. 2019 ;2019:4145821. Epub 2019 Oct 13. PMID: 31737126
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Heart Failure, Vitamin C Deficiency
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Factors
[+]

Vitamin D deficiency is highly prevalent in US adults (especially African-Americans) with cardiovascular diseases, particularly coronary heart disease and heart failure.Dec 01, 2008

Pubmed Data : Am J Cardiol. 2008 Dec 1;102(11):1540-4. Epub 2008 Sep 24. PMID: 19026311
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : African-American Specific Deficiencies/Diseases, Cardiovascular Diseases, Coronary Artery Disease, Heart Failure
[+]

Vitamin D(3) reduces the inflammatory milieu in congestive heart failure patients and might serve as a new antiinflammatory agent for the future treatment of the disease.Apr 01, 2006

Pubmed Data : Am J Clin Nutr. 2006 Apr;83(4):754-9. PMID: 16600924
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Congestive Heart Failure, Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Waltz dancing is able to improve functional capacity in patients with chronic heart failure. Jul 01, 2008

Pubmed Data : Circ Heart Fail. 2008 Jul;1(2):107-14. Epub 2008 May 28. PMID: 19808280
Article Published Date : Jul 01, 2008
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Dancing
[+]

Waon therapy is an innovative and promising therapy for patients with chronic heart failure.Sep 30, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cardiol. 2008 Oct ;52(2):79-85. Epub 2008 Aug 27. PMID: 18922381
Article Published Date : Sep 30, 2008
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Thermal Therapy: Far-Infrared
Pharmacological Actions : Cardioprotective
[+]

Waon therapy, a holistic soothing warmth therapy, showed clinical advantages in safety and efficacy among patients with advanced heart failure.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Circ J. 2016 ;80(4):827-34. Epub 2016 Mar 18. PMID: 27001189
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Thermal Therapy: Far-Infrared
Additional Keywords : Heart Failure, Thermal Therapy: Far-Infrared
[+]

Yoga may be an alternative or complementary option to established forms of exercise training such as hydrotherapy for in patients with heart failure.May 31, 2017

Pubmed Data : Eur J Cardiovasc Nurs. 2017 Jun ;16(5):381-389. Epub 2017 Jan 27. PMID: 28128646
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Depression, Heart Failure
Therapeutic Actions : Hydrotherapy , Yoga
Pharmacological Actions : Antidepressive Agents
[+]

Yoga therapy offered additional benefits to the standard medical care of predominantly African American Heart Failure Patients patients by improving cardiovascular endurance, Quality of Life, inflammatory markers and flexibility.Nov 27, 2009

Pubmed Data : Med Sci Sports Exerc. 2009 Nov 27. Epub 2009 Nov 27. PMID: 19952833
Article Published Date : Nov 27, 2009
Study Type : Human Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Yoga
[+]

Acute exposure to CS tear gas has been reported to cause several health problems in an individual.Dec 26, 1981

Pubmed Data : Schweiz Med Wochenschr. 1981 Dec 26 ;111(52):2056-60. PMID: 6800031
Article Published Date : Dec 26, 1981
Study Type : Human: Case Report
Additional Links
Diseases : Chemically-Induced Liver Damage, Heart Failure, Liver Damage, Pneumonia
Problem Substances : 2-chlorobenzylidene malononitrile (CS)
[+]

D-ribose has been reported to achieve significant functional improvement in a case of cardiomyopathy.Mar 01, 2010

Pubmed Data : J Altern Complement Med. 2010 Mar;16(3):323-5. PMID: 20156124
Article Published Date : Mar 01, 2010
Study Type : Human: Case Report
Additional Links
Substances : D-Ribose
Diseases : Heart Failure
[+]

This case highlights the potential role of a plant-based diet in helping to reverse heart failure with reduced ejection fraction.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2019 ;6:82. Epub 2019 Jun 11. PMID: 31245377
Article Published Date : Dec 31, 2018
Study Type : Human: Case Report, Review
Additional Links
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Dietary Modification
[+]

18β-glycyrrhetinic acid improves cardiac diastolic function by attenuating intracellular calcium overload.Jul 31, 2020

Pubmed Data : Curr Med Sci. 2020 Aug ;40(4):654-661. Epub 2020 Aug 29. PMID: 32862375
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : 18β-Glycyrrhetinic Acid
Diseases : Heart Failure, Myocardial Ischemia
Pharmacological Actions : Cardioprotective
[+]

A berberine derivative attenuates cardiac failure. Feb 01, 2010

Pubmed Data : Acta Pharmacol Sin. 2010 Feb;31(2):165-74. PMID: 20139899
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Heart Failure, Myocardial Infarction
Pharmacological Actions : Antioxidants
[+]

A multi-herbal product called Protandim prevents fibrosis and capillary loss and preserves right ventricular function in rats.Nov 17, 2009

Pubmed Data : Circulation. 2009 Nov 17;120(20):1951-60. Epub 2009 Nov 2. PMID: 19884466
Article Published Date : Nov 17, 2009
Study Type : Animal Study
Additional Links
Substances : Ashwagandha, Bacopa, Green Tea, Milk Thistle, Protandim, Turmeric
Diseases : Heart Failure, Hypertension, Hypertension: Pulmonary
Pharmacological Actions : Anti-Fibrotic, Vascular Endothelial Growth Factor A Inhibitor
[+]

A water extract of the heartwood of Pterocarpus compares favorably to digoxin as a cardiotonic agent. Jun 01, 2007

Pubmed Data : Indian J Exp Biol. 2007 Jun;45(6):532-7. PMID: 17585688
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Substances : Pterocarpus marsupium
Diseases : Heart Failure
Pharmacological Actions : Cardiotonic Agents
Additional Keywords : Drug: Digoxin, Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Administration of deep sea minerals can be an effective strategy to improve the life expectancy of diabetic subjects.Jun 30, 2016

Pubmed Data : Environ Toxicol. 2016 Jul ;31(7):769-81. Epub 2015 Mar 2. PMID: 25727812
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Water: Deep Sea
Diseases : Diabetic Complications, Heart Failure
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
Additional Keywords : Anti-Apoptotic, Cardioprotective, Diabetic Complications, Heart Failure, Water: Deep Sea
[+]

Asiatic acid attenuates the progression of left ventricular hypertrophy and heart failure induced by pressure overload.Nov 30, 2015

Pubmed Data : J Cardiovasc Pharmacol. 2015 Dec ;66(6):558-68. PMID: 26647013
Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Cardiac Hypertrophy, Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-6 Downregulation
[+]

Asiatic acid protects against cardiac hypertrophy.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biol Sci. 2016 ;12(7):861-71. Epub 2016 May 25. PMID: 27313499
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Cardiac Hypertrophy, Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Astragaloside IV alleviated heart failure by promoting angiogenesis through JAK-STAT3 pathway.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2019 Dec ;57(1):48-54. PMID: 30905241
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Heart Failure
Pharmacological Actions : Angiogenesis Inducing Agents
[+]

Astragalus membranaceus has a therapeutic effect on sodium and water retention in experimental heart failure.Jan 01, 1998

Pubmed Data : Chin Med J (Engl). 1998 Jan;111(1):17-23. PMID: 10322646
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Substances : Astragalus
Diseases : Heart Failure, Water Retention
Pharmacological Actions : Atrial Natriuretic Factor Modulation, Natriuretic Agents
[+]

Baicalein alleviated myocardial remodelling and improved cardiac function.Jan 14, 2016

Pubmed Data : Life Sci. 2016 Jan 15 ;145:213-23. Epub 2015 Dec 17. PMID: 26706290
Article Published Date : Jan 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Baicalein
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Cardioprotective, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Berberine produced myocardial salvaging effects in the setting of diabetes challenged with ISP induced myocardial necrosis.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2016 Mar ;10(3):FF13-8. Epub 2016 Mar 1. PMID: 27134894
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Diabetes Mellitus: Type 2, Diabetic Complications, Heart Failure
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

C. sativum extract provides significant protection from heart failure.Oct 08, 2018

Pubmed Data : J Diet Suppl. 2018 Oct 9:1-14. Epub 2018 Oct 9. PMID: 30299180
Article Published Date : Oct 08, 2018
Study Type : Animal Study
Additional Links
Substances : Coriandrum sativum
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Calcitriol increases ventricular K+ currents in isolated mouse cardiomyocytes.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2018 ;9:1186. Epub 2018 Aug 24. PMID: 30197603
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Cardiac Hypertrophy, Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Chlorogenic acid has profound cardioprotective effects through inhibiting the activation of NF-κB and JNK pathway.Apr 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Apr 29. Epub 2019 Apr 29. PMID: 31033175
Article Published Date : Apr 28, 2019
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Heart Failure, Inflammation
Pharmacological Actions : Cardioprotective
[+]

Chronic exercise training prevents coronary artery stiffening.Jul 10, 2019

Pubmed Data : J Appl Physiol (1985). 2019 Jul 11. Epub 2019 Jul 11. PMID: 31295062
Article Published Date : Jul 10, 2019
Study Type : Animal Study
Additional Links
Diseases : Arterial Hardening: Elasticity, Heart Failure
Therapeutic Actions : Exercise
Pharmacological Actions : Vasoprotective
[+]

Corydalis yanhusuo exerted salutary effects on heart failure induced by myocardial infarction in rats.May 01, 2007

Pubmed Data : J Pharm Pharmacol. 2007 May;59(5):695-701. PMID: 17524235
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : Corydalis Yanhusuo
Diseases : Heart Failure, Myocardial Infarction
[+]

Curcumin could be considered as an add-on therapeutic agent in the treatment of fibrosis-derived heart failure patient who is intolerant of ACE inhibitor therapy.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2015 ;9:6043-54. Epub 2015 Nov 11. PMID: 26648693
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Heart Failure, Myocardial Infarction
Pharmacological Actions : Cardioprotective
[+]

Curcumin could improve cardiac function in heart failure.Apr 01, 2010

Pubmed Data : Zhonghua Xin Xue Guan Bing Za Zhi. 2010 Apr;38(4):369-73. PMID: 20654087
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Curcumin has a beneficial therapeutic effect in diabetes-induced heart failure. May 31, 2014

Pubmed Data : J Biochem Mol Toxicol. 2014 Jun ;28(6):263-70. Epub 2014 Apr 24. PMID: 24760747
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Diabetic Complications, Heart Failure, Oxidative Stress
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin may inhibit cardiac hypertrophy and myocardial infarction.Oct 19, 2009

Pubmed Data : Lab Invest. 2009 Oct 19. PMID: 18292806
Article Published Date : Oct 19, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cardiac Hypertrophy, Cardiomegaly, Heart Failure, Myocardial Infarction
Pharmacological Actions : Cardioprotective, Enzyme Inhibitors
[+]

Curcumin may provide an ideal therapeutic agent in the treatment of heart failure.Mar 01, 2008

Pubmed Data : J Clin Invest. 2008 Mar;118(3):868-78. PMID: 18292809
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Heart Failure
[+]

Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling in rats with congestive heart failure.Jan 01, 2008

Pubmed Data : Int J Mol Med. 2008 Jan;21(1):117-24. PMID: 18097624
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Epimedium
Diseases : Congestive Heart Failure, Heart Failure, Left Ventricular Dysfunction
[+]

Exercise training improves the IL-10/TNF-α cytokine balance in the gastrocnemius of rats with heart failure.Sep 06, 2017

Pubmed Data : Braz J Phys Ther. 2017 Sep 7. Epub 2017 Sep 7. PMID: 28939262
Article Published Date : Sep 06, 2017
Study Type : Animal Study
Additional Links
Diseases : Heart Failure, Inflammation
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Exercise training restores cardiac protein quality control in heart failure.Dec 31, 2011

Pubmed Data : PLoS One. 2012 ;7(12):e52764. Epub 2012 Dec 27. PMID: 23300764
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Exercise
[+]

Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.Jan 01, 2009

Pubmed Data : Immunopharmacol Immunotoxicol. 2009;31(2):209-13. PMID: 19015135
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flaxseed, Omega-3 Fatty Acids
Diseases : Adiponectin: Low Levels, Heart Failure, Hypertension
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Flax Versus Fish Oil
[+]

Galangin ameliorates cardiac remodeling via the MEK1/2-ERK1/2 and PI3K-AKT pathways.Feb 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Physiol. 2019 Feb 11. Epub 2019 Feb 11. PMID: 30741414
Article Published Date : Feb 10, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cardioprotective
[+]

Gallic acid has therapeutic potential for the treatment of heart failure-induced pulmonary fibrosis.Nov 30, 2017

Pubmed Data : Vascul Pharmacol. 2017 Dec ;99:74-82. Epub 2017 Oct 31. PMID: 29097327
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Heart Failure, Myocardial Fibrosis
Pharmacological Actions : Anti-Fibrotic
[+]

Ginkgo biloba extract has potential therapeutic effects in relieving depressive status of patients with heart failure.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2019 ;15:3041-3050. Epub 2019 Oct 29. PMID: 31754303
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Brain Inflammation , Depression, Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginsenoside Rb1 improves cardiac function and remodeling in heart failure.Aug 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Anim. 2017 Aug 5 ;66(3):217-228. Epub 2017 Mar 30. PMID: 28367863
Article Published Date : Aug 04, 2017
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Phytotherapy
[+]

Hawthorn demonstrates a modest beneficial effects on cardiac remodeling and function during long-term, pressure overload-induced heart failure in rats.Jun 01, 2009

Pubmed Data : Pharmacotherapy. 2009 Jun;29(6):639-48. PMID: 19476417
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Hawthorn
Diseases : Heart Failure
Additional Keywords : Plant Extracts
[+]

LED therapy was able to increase the functional capacity evaluated by distance covered, time, and speed of exercise in rats with HF.Apr 07, 2016

Pubmed Data : Lasers Med Sci. 2016 Apr 8. Epub 2016 Apr 8. PMID: 27059227
Article Published Date : Apr 07, 2016
Study Type : Animal Study
Additional Links
Diseases : Fatigue, Heart Failure
Therapeutic Actions : Exercise, Light-Emitting Diodes (LEDs) Therapy
[+]

Lovastatin causes depletion of coenzyme Q10 levels in the cardiac muslce and mitochondria of animals.Jul 06, 1994

Pubmed Data : Biochim Biophys Acta. 1994 Jul 6 ;1200(2):100-8. PMID: 8031828
Article Published Date : Jul 06, 1994
Study Type : Animal Study
Additional Links
Diseases : Coenzyme Q10 Deficiency, Drug-Induced Nutrient Depletion: Statin Drugs, Heart Failure, Statin-Induced Pathologies
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Cardiotoxic, Myotoxicity
[+]

Luteolin ameliorated the myocardium fibrosis of heart failure.Jan 22, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jan 23 ;7:41017. Epub 2017 Jan 23. PMID: 28112209
Article Published Date : Jan 22, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Heart Failure
Pharmacological Actions : Anti-Fibrotic, Cardioprotective
[+]

Lycium barbarum polysaccharides restore adverse structural remodelling and cardiac contractile dysfunction.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2018 Oct ;22(10):4830-4839. Epub 2018 Aug 17. PMID: 30117672
Article Published Date : Sep 30, 2018
Study Type : Transgenic Animal Study
Additional Links
Substances : Goji
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Mangiferin exert cardioprotective and anti-apoptotic effects in heart failure.May 14, 2020

Pubmed Data : Life Sci. 2020 May 15 ;249:117476. Epub 2020 Feb 28. PMID: 32119962
Article Published Date : May 14, 2020
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
[+]

Mice receiving EGCG have a lower mortality rate and exhibit less inflammation and a better preserved cardiac function and telomere biology.Jun 29, 2016

Pubmed Data : J Cardiol. 2016 Jun 30. Epub 2016 Jun 30. PMID: 27374189
Article Published Date : Jun 29, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Cardiac Mortality , Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Telomere Protective
Additional Keywords : Mortality
[+]

Mitigating effect of tanshinone IIA on ventricular remodeling in rats with pressure overload-induced heart failure.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Cir Bras. 2019 ;34(8):e201900807. Epub 2019 Oct 14. PMID: 31618407
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
[+]

Paeoniflorin attenuates myocardial fibrosis in isoprenaline-induced chronic heart failure.Mar 31, 2020

Pubmed Data : Curr Med Sci. 2020 Apr ;40(2):307-312. Epub 2020 Apr 26. PMID: 32337690
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Heart Failure, Myelofibrosis
Pharmacological Actions : Anti-Fibrotic, Cardioprotective
[+]

Paeoniflorin attenuates pressure overload-induced cardiac remodeling.May 31, 2013

Pubmed Data : J Mol Histol. 2013 Jun ;44(3):357-67. Epub 2013 Feb 17. PMID: 23417833
Article Published Date : May 31, 2013
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Cardiomegaly, Heart Failure, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin could attenuate cardiac remodelling and improve cardiac function in chronic heart failure.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Diagn Ther. 2019 Jun ;9(3):272-280. PMID: 31275817
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Panax ginseng combined with berberine has a positive effect in experimental rats with chronic congestive heart failure. Feb 01, 2009

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2009 Feb;34(3):324-7. PMID: 19445159
Article Published Date : Feb 01, 2009
Study Type : Animal Study
Additional Links
Substances : Berberine, Panax Ginseng
Diseases : Congestive Heart Failure, Heart Failure
[+]

Pterostilbene improves cardiac function in a rat model of right heart failure.Mar 18, 2020

Pubmed Data : Appl Physiol Nutr Metab. 2020 Mar 19. Epub 2020 Mar 19. PMID: 32191845
Article Published Date : Mar 18, 2020
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Heart Failure
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Puerarin attenuates pressure overload-induced cardiac hypertrophy.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cardiol. 2014 Jan ;63(1):73-81. Epub 2013 Jul 29. PMID: 23906530
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Phytotherapy
[+]

Puerarin inhibits apoptosis and inflammation in myocardial cells via PPARα expression in rats with chronic heart failure.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Nov ;18(5):3347-3356. Epub 2019 Sep 6. PMID: 31602208
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Puerarin protects against heart failure induced by pressure overload through mitigation of ferroptosis.Jan 25, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 02 26 ;497(1):233-240. Epub 2018 Feb 8. PMID: 29427658
Article Published Date : Jan 25, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Heart Failure, Hypertension
Pharmacological Actions : Anti-Apoptotic, Cardioprotective, Vasodilator Agents
[+]

Reduction of atrial fibrillation by tanshinone IIA in chronic heart failure.Nov 30, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec ;84:1760-1767. Epub 2016 Nov 12. PMID: 27847200
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Repeated sauna therapy increases eNOS expression and NO production in cardiomyopathic hamsters with heart failure.Jun 01, 2005

Pubmed Data : Circ J. 2005 Jun;69(6):722-9. PMID: 15914953
Article Published Date : Jun 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Endothelial Dysfunction, Heart Failure
[+]

Repeated thermal therapy upregulates arterial endothelial nitric oxide synthase expression.Apr 30, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Jpn Circ J. 2001 May ;65(5):434-8. PMID: 11348049
Article Published Date : Apr 30, 2001
Study Type : Animal Study
Additional Links
Diseases : Endothelial Dysfunction, Heart Failure
Therapeutic Actions : Thermal Therapy: Far-Infrared
Pharmacological Actions : Nitric Oxide Enhancer
[+]

Restoration of appropriate testosterone levels may have therapeutic value in the treatment of heart failure.Apr 28, 2011

Pubmed Data : Gen Comp Endocrinol. 2011 Apr 28. Epub 2011 Apr 28. PMID: 21549119
Article Published Date : Apr 28, 2011
Study Type : Animal Study
Additional Links
Substances : Testosterone
Diseases : Androgen Deficiency, Congestive Heart Failure, Heart Failure
Pharmacological Actions : β(2)-adrenoceptor up-regulation
Additional Keywords : Chemotherapy Induced Toxicity, Drug: Doxorubicin
[+]

Resveratrol may prevent cardiac dysfunction in diabetics. Dec 01, 2010

Pubmed Data : Free Radic Biol Med. 2010 Dec 1;49(11):1710-21. Epub 2010 Sep 7. PMID: 20828608
Article Published Date : Dec 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Diabetes: Cardiovascular Illness, Heart Failure, Myocardial Infarction
Pharmacological Actions : Cardioprotective, Hypoglycemic Agents, Vasodilator Agents
Additional Keywords : Drug Synergy, Stilbenes
[+]

Shikonin attenuates sympathetic remodeling in chronic heart failure.Oct 07, 2019

Pubmed Data : Biochem Biophys Res Commun. 2019 Oct 8. Epub 2019 Oct 8. PMID: 31604527
Article Published Date : Oct 07, 2019
Study Type : Animal Study
Additional Links
Substances : Shikonin
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective, MicroRNA modulator
[+]

Shikonin treatment attenuated Isoproterenol induced heart injury, providing an effective therapeutic strategy for heart failure treatment for future.Aug 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Sep ;93:1343-1357. Epub 2017 Jul 24. PMID: 28753907
Article Published Date : Aug 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Anti-Inflammatory Agents, Cardioprotective
[+]

Soy isoflavones in the maternal diet provides cardioprotection to the hearts of their offspring during adulthood.Apr 01, 2003

Pubmed Data : Clin Radiol. 2003 Apr;58(4):301-5. PMID: 15778278
Article Published Date : Apr 01, 2003
Study Type : Animal Study
Additional Links
Substances : Isoflavones, phytoestrogens, Soy
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Sulforaphane improved cardiac function and remodelling by inhibiting oxidative stress and inflammation.Mar 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2018 Mar 12 ;24:1473-1483. Epub 2018 Mar 12. PMID: 29527002
Article Published Date : Mar 11, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

Sustained 35-GHz radiofrequency irradiation induces circulatory failure.Sep 30, 1995

Pubmed Data : Shock. 1995 Oct ;4(4):289-93. PMID: 8564558
Article Published Date : Sep 30, 1995
Study Type : Animal Study
Additional Links
Diseases : Heart Failure, Hypertension
Anti Therapeutic Actions : 5G Millimeter Wave Radiation
[+]

Testosterone has neuroprotective effects upon cardiac sympathetic function in rats with induced heart failure.Oct 01, 2009

Pubmed Data : Eur J Pharmacol. 2009 Oct 1;619(1-3):68-74. Epub 2009 Aug 6. PMID: 19665014
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Testosterone
Diseases : Heart Failure
Pharmacological Actions : Anti-Androgen, Cardioprotective, Neuroprotective Agents
[+]

The flavonaids of propolis have inhibitory effect on apoptosis of myocardial cells of chronic heart failure induced by adriamycin in rats.Apr 30, 2015

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 May ;31(3):201-6. PMID: 26387177
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Propolis: Bee
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Cardioprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

The protective role of lutein on isoproterenol-induced cardiac failure.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2019 Dec ;57(1):529-535. PMID: 31411934
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Lutein
Diseases : Heart Failure
Pharmacological Actions : Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Isoproterenol
[+]

The results show that oleuropein attenuates the progression of heart failure.Feb 28, 2017

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2017 Mar ;390(3):245-252. Epub 2016 Dec 8. PMID: 27928616
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Heart Failure, Myocardial Infarction, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Heart Failure, Myocardial Infarction, Oleuropein, oxidative stress
[+]

The use of a combination of Q10, L-arginine, and vitamin D could be a potential method to reduce myocardial injury or the effects of aging on the heart.Dec 31, 2017

Pubmed Data : J Vasc Res. 2018 ;55(1):47-60. Epub 2018 Jan 5. PMID: 29301117
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Arginine, Coenzyme Q10, Vitamin D
Diseases : Aging: Heart, Heart Failure
Pharmacological Actions : Antioxidants, Cardioprotective, Vasodilator Agents
Additional Keywords : Natural Substance Synergy
[+]

These findings reveal that acute fluoride exposure causes sudden heart failure.Feb 14, 2017

Pubmed Data : Int J Cardiol. 2017 Feb 15 ;229:96-101. Epub 2016 Nov 9. PMID: 27863940
Article Published Date : Feb 14, 2017
Study Type : Animal Study
Additional Links
Diseases : Fluoride Toxicity , Heart Failure
Problem Substances : Fluoride, Sodium Fluoride
Adverse Pharmacological Actions : Cardiotoxic
[+]

These results indicated that Grb1 can exert anti- heart failure function by inhibiting cardiomyocyte autophagy.Mar 24, 2018

Pubmed Data : J Pharm Pharmacol. 2018 Mar 25. Epub 2018 Mar 25. PMID: 29574918
Article Published Date : Mar 24, 2018
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Heart Failure
Pharmacological Actions : Autophagy Inhibitors, Cardioprotective
[+]

These results suggest that goji polysaccharides present anti-inflammatory and antioxidant effects with utility in a heart failure model.Jan 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Jan 22 ;25(3). Epub 2020 Jan 22. PMID: 31979068
Article Published Date : Jan 21, 2020
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Treatment with resveratrol significantly improved cardiac dysfunction and reduced BNP expression in rats with heart failure. Jul 06, 2015

Pubmed Data : J Cardiovasc Pharmacol. 2015 Jul 7. Epub 2015 Jul 7. PMID: 26167810
Article Published Date : Jul 06, 2015
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Cardiovascular Disease, Heart Failure
Pharmacological Actions : Autophagy Inhibitors, Cardioprotective
Additional Keywords : Risk Reduction
[+]

Treatment with α-lipoic acid can prevent cardiac hyperplasia and dysfunction.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2019 Aug ;5(8):e02371. Epub 2019 Aug 28. PMID: 31517099
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Vitamin D improves cardiac function after myocardial infarction through modulation of resident cardiac progenitor cells.Jul 31, 2018

Pubmed Data : Heart Lung Circ. 2018 Aug ;27(8):967-975. Epub 2018 Feb 3. PMID: 29573957
Article Published Date : Jul 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Heart Failure, Myocardial Infarction
Pharmacological Actions : Cardioprotective
[+]

A summary of published evidence of far-infrared saunas for treatment of cardiovascular risk factors.Jun 30, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Can Fam Physician. 2009 Jul ;55(7):691-6. PMID: 19602651
Article Published Date : Jun 30, 2009
Study Type : Review
Additional Links
Diseases : Cardiovascular Diseases, Chronic Fatigue Syndrome, Coronary Artery Disease, Heart Failure
Therapeutic Actions : Thermal Therapy: Far-Infrared
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Risk Reduction
[+]

Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan.Mar 13, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Circ Res. 2008 Mar 14 ;102(5):597-606. Epub 2008 Jan 17. PMID: 18202313
Article Published Date : Mar 13, 2008
Study Type : In Vitro Study
Additional Links
Diseases : Aging, Heart Failure
Pharmacological Actions : Antiproliferative , Apoptotic, Neocardiogenic
Additional Keywords : cardiac progenitor cells
[+]

All data reviewed indicate that hawthorn is well tolerated, but more data are needed on concomitant use of hawthorn and other medications.Jan 01, 2006

Pubmed Data : Drug Saf. 2006 ;29(6):523-35. PMID: 16752934
Article Published Date : Jan 01, 2006
Study Type : Review
Additional Links
Substances : Hawthorn
Diseases : Heart Failure
Additional Keywords : Phytotherapy, Plant Extracts, Safety Study
[+]

Astragaloside IV alleviates heart failure via activating PPARα to switch glycolysis to fatty acid β-oxidation.Jun 01, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jun 2 ;7(1):2691. Epub 2017 Jun 2. PMID: 28578382
Article Published Date : Jun 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Astragaloside IV protects cardiomyocytes from hypoxia-induced injury,May 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 May 25 ;116:109028. Epub 2019 May 25. PMID: 31136949
Article Published Date : May 24, 2019
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Heart Failure, Hypoxia
Pharmacological Actions : Cardioprotective
[+]

Berberine has cardiovascular effects which may benefit arrhythmias and/or heart failure.Sep 01, 2001

Pubmed Data : Cardiovasc Drug Rev. 2001 Fall;19(3):234-44. PMID: 11607041
Article Published Date : Sep 01, 2001
Study Type : Commentary
Additional Links
Substances : Berberine
Diseases : Cardiac Arrhythmias, Heart Failure
[+]

Ca2+, Mg2+, Zn, and Se have an important role in congestive heart failure. Oct 01, 2007

Pubmed Data : Cardiovasc Hematol Agents Med Chem. 2007 Oct;5(4):295-9. PMID: 17979692
Article Published Date : Oct 01, 2007
Study Type : Review
Additional Links
Substances : Calcium, Magnesium, Selenium, Zinc
Diseases : Congestive Heart Failure, Heart Failure
[+]

Clinical evidence for Q10 coenzyme supplementation in heart failure.Apr 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2020 Apr 27 ;9(5). Epub 2020 Apr 27. PMID: 32349341
Article Published Date : Apr 26, 2020
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Coenzyme Q10 - A new player in the treatment of heart failure? Sep 30, 2016

Pubmed Data : Pharmacol Rep. 2016 Oct ;68(5):1015-9. Epub 2016 Jul 17. PMID: 27428763
Article Published Date : Sep 30, 2016
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Coenzyme Q10 in cardiovascular and metabolic diseases.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Cardiol Rev. 2018 ;14(3):164-174. PMID: 29663894
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Dyslipidemias, Heart Disease: Ischemic, Heart Failure, Hypertension, Myocardial Infarction, Myocarditis: Viral
Pharmacological Actions : Cardioprotective
[+]

Coenzyme Q10 is an effective adjunctive treatment in congestive heart failure. Jan 01, 1997

Pubmed Data : Mol Aspects Med. 1997;18 Suppl:S159-68. PMID: 9266518
Article Published Date : Jan 01, 1997
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Congestive Heart Failure, Heart Failure
[+]

Coenzyme Q10 may be an effective adjunctive treatment of chronic heart failure. Sep 01, 2009

Pubmed Data : Med Hypotheses. 2009 Sep;73(3):306-8. Epub 2009 May 5. PMID: 19409711
Article Published Date : Sep 01, 2009
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Drug-Induced Nutrient Depletion: Statin Drugs, Heart Failure, Statin-Induced Pathologies
[+]

Curcumin may play a therapeutic role in heart failure.Oct 01, 2007

Pubmed Data : J Food Sci. 2007 Oct;72(8):S612-7. PMID: 20467147
Article Published Date : Oct 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cardiomegaly, Heart Failure
[+]

D-ribose may provide the necessary metabolic substrate to benefit this energy-deficient state found in heart failure.Jun 01, 2009

Pubmed Data : Prog Cardiovasc Nurs. 2009 Jun;24(2):59-60. PMID: 19523159
Article Published Date : Jun 01, 2009
Study Type : Commentary
Additional Links
Substances : D-Ribose
Diseases : Congestive Heart Failure, Heart Failure
[+]

Deficiencies and/or abberations in the levels of Ca(2+), Mg(2+), vitamin D, zinc and selenium appear to be an integral component of pathophysiologic expressions of CHF that contributes to its systemic and progressive nature.Dec 01, 2007

Pubmed Data : Clin Med Res. 2007 Dec;5(4):238-43. PMID: 18367709
Article Published Date : Dec 01, 2007
Study Type : Review
Additional Links
Substances : Calcium, Magnesium, Selenium, Vitamin D
Diseases : Congestive Heart Failure, Heart Failure
[+]

Evidence suggests that the coenzyme Q10 supplement may be a useful tool for managing patients with heart failure.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian Heart J. 2018 Jul ;70 Suppl 1:S111-S117. Epub 2018 Jan 31. PMID: 30122240
Article Published Date : Jun 30, 2018
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Cardiovascular Diseases, Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Exercise induces new cardiomyocyte generation in the adult mammalian heart.Jan 24, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nat Commun. 2018 04 25 ;9(1):1659. Epub 2018 Apr 25. PMID: 29695718
Article Published Date : Jan 24, 2018
Study Type : Review
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Exercise
Pharmacological Actions : Cardioprotective
Additional Keywords : Heart Regeneration
[+]

Ginsenoside Rb3 regulates energy metabolism and apoptosis in cardiomyocytes via activating PPARα pathway.Sep 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Sep 29 ;120:109487. Epub 2019 Sep 29. PMID: 31577975
Article Published Date : Sep 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
[+]

Kaempferol prevents against Ang II-induced cardiac remodelling through attenuating Ang II-induced inflammation and oxidative stress.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cardiovasc Pharmacol. 2019 Oct ;74(4):326-335. PMID: 31356553
Article Published Date : Sep 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Heart Failure
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

Lovastatin-induced cardiac toxicity involves both oncotic and apoptotic cell death.Dec 15, 2003

Pubmed Data : Toxicol Appl Pharmacol. 2003 Dec 15 ;193(3):346-55. PMID: 14678744
Article Published Date : Dec 15, 2003
Study Type : In Vitro Study
Additional Links
Diseases : Heart Failure, Statin-Induced Pathologies
Pharmacological Actions : Apoptotic
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic, Cytotoxic
[+]

Meditation may offer a patient-driven practice to reduce heart failure symptoms as well as improve psychosocial wellness and quality of life.Jul 22, 2019

Pubmed Data : Eur J Cardiovasc Nurs. 2019 Jul 23:1474515119863181. Epub 2019 Jul 23. PMID: 31331192
Article Published Date : Jul 22, 2019
Study Type : Review
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Meditation
Pharmacological Actions : Antidepressive Agents
[+]

Meta-Analysis: L-arginine has a wide range of potential therapeutic applications.Jan 01, 1999

Pubmed Data : J Med. 1999;30(3-4):131-48. PMID: 17312667
Article Published Date : Jan 01, 1999
Study Type : Review
Additional Links
Substances : Arginine
Diseases : Aging, Coronary Artery Disease, Diabetes Mellitus: Type 2, Heart Failure, Hypercholesterolemia, Peripheral Vascular Diseases, Smoking
[+]

Noble heart failure therapy using food compositions.Dec 31, 2017

Pubmed Data : Yakugaku Zasshi. 2018 ;138(10):1263-1269. PMID: 30270270
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Diabetes Mellitus: Type 2, Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Phytotherapy
[+]

Regulation of autophagy in cardiovascular diseases by natural products.Dec 31, 2019

Pubmed Data : Adv Exp Med Biol. 2020 ;1207:731-736. PMID: 32671790
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Resveratrol
Diseases : Atherosclerosis, Cardiovascular Diseases, Heart Failure
Pharmacological Actions : Cardioprotective
[+]

Resveratrol improves cell survival in chronic heart failure. Mar 12, 2010

Pubmed Data : J Biol Chem. 2010 Mar 12;285(11):8375-82. Epub 2010 Jan 20. PMID: 20089851
Article Published Date : Mar 12, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Heart Failure, Myocardial Infarction, Oxidative Stress
Pharmacological Actions : Anti-Fibrotic, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Sauna therapy and exercise act by raising the availability of tetrahydrobiopterin?Oct 01, 2009

Pubmed Data : Med Hypotheses. 2009 Oct ;73(4):610-3. Epub 2009 Jul 5. PMID: 19581054
Article Published Date : Oct 01, 2009
Study Type : Review
Additional Links
Diseases : Chronic Fatigue Syndrome, Endothelial Dysfunction, Fibromyalgia, Heart Failure, Multiple Chemical Sensitivity, Tetrahydrobiopterin Deficiency
Therapeutic Actions : Sauna Therapy
Additional Keywords : Heat Shock Protein Inducer
[+]

Scientific evidence shows that WS 1442 is safe and has a beneficial effect in patients with heart failure.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Cardiovasc Drugs. 2018 Feb ;18(1):25-36. PMID: 29080984
Article Published Date : Jan 31, 2018
Study Type : Review
Additional Links
Substances : Flavonoids, Hawthorn
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Statin drugs result in coq10 depletion associated with congestive heart failure and which may be rectified by supplementation. Jan 01, 2003

Pubmed Data : Biofactors. 2003;18(1-4):101-11. PMID: 14695925
Article Published Date : Jan 01, 2003
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Drug-Induced Nutrient Depletion: Statin Drugs, Heart Failure, Statin-Induced Pathologies
Additional Keywords : Drug-Nutrient Depletion, Statin-Coq10 Depletion
[+]

Statin therapy may cause insulin resistance which may negate their purported beneficial effects on cardiac remodelling in heart failure.Feb 03, 2011

Pubmed Data : Int J Cardiol. 2011 Feb 3 ;146(3):417. Epub 2010 May 18. PMID: 20483495
Article Published Date : Feb 03, 2011
Study Type : Review
Additional Links
Diseases : Heart Failure, Insulin Resistance
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance
[+]

statin-induced inhibition of protein synthesis is an underlying mechanism for statin-induced cardiomyocyte cell death.Jan 01, 2007

Pubmed Data : Cardiovasc Toxicol. 2007 ;7(1):1-9. PMID: 17646677
Article Published Date : Jan 01, 2007
Study Type : In Vitro Study
Additional Links
Diseases : Heart Failure, Statin-Induced Pathologies
Pharmacological Actions : Apoptotic
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic, Cytotoxic
[+]

Supplemental Coenzyme Q10 may be a useful option for effective management of patients with heart failure.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Open Heart. 2015 ;2(1):e000326. Epub 2015 Oct 19. PMID: 26512330
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Heart Failure
Additional Keywords : Risk Reduction
[+]

Tanshinone IIA could represent a promising candidate for heart failure therapy.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2016 ;8(7):3124-32. Epub 2016 Jul 15. PMID: 27508033
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Heart Failure
Pharmacological Actions : Cardioprotective, MicroRNA modulator
[+]

Tanshinone IIA protects against heart failure post-myocardial infarction.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Apr ;112:108599. Epub 2019 Feb 21. PMID: 30798134
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Heart Failure, Myocardial Infarction
Pharmacological Actions : Anti-Apoptotic, Autophagy Inhibitors, Cardioprotective
Additional Keywords : Risk Reduction
[+]

Taurine protects against cardiac dysfunction induced by pressure overload through SIRT1-p53 activation.Jan 31, 2020

Pubmed Data : Chem Biol Interact. 2020 Feb 1:108972. Epub 2020 Feb 1. PMID: 32017914
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Taurine
Diseases : Heart Failure
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective
[+]

The adverse effects of statins may be amplified in the elderly, and include cancer, neurodegenerative conditions, heart failure and accelerated aging. May 01, 2005

Pubmed Data : Expert Opin Drug Saf. 2005 May ;4(3):389-97. PMID: 15934847
Article Published Date : May 01, 2005
Study Type : Commentary
Additional Links
Diseases : Cancers: All, Elderly: Age Specific Diseases, Heart Failure, Neurodegenerative Diseases, Statin-Induced Pathologies
Problem Substances : Statin Drugs
[+]

The cognitive benefits through exercise could extend to persons with heart failure.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Aging Phys Act. 2015 ;12:6. Epub 2015 Oct 23. PMID: 26865870
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Exercise
[+]

The statin drug lovastatin induces concentration-dependent cell death in cardiomyoctyes.Jan 01, 2008

Pubmed Data : Pharmacology. 2008 ;82(1):74-82. Epub 2008 May 27. PMID: 18504415
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Diseases : Heart Failure, Statin-Induced Pathologies
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Cardiotoxic, Cytotoxic
[+]

There are multiple potential benefits to ginseng in cancer.Jan 26, 2019

Pubmed Data : Am J Hosp Palliat Care. 2019 Jan 27:1049909118822704. Epub 2019 Jan 27. PMID: 30686023
Article Published Date : Jan 26, 2019
Study Type : Review
Additional Links
Substances : Ginseng
Diseases : Cancers: All, Dementia, Fatigue, Heart Failure, Respiratory Diseases
Pharmacological Actions : Chemopreventive
[+]

These results suggest that gallic acid is a therapeutic agent for cardiac dysfunction and fibrosis in chronic heart failure.Jun 17, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Jun 18 ;8(1):9302. Epub 2018 Jun 18. PMID: 29915390
Article Published Date : Jun 17, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Heart Failure
Pharmacological Actions : Anti-Fibrotic, Cardioprotective
[+]

This article serves to examine recent evidence supporting the sympatholytic, vasodilatory, and cardioprotective effects of acupuncture.Dec 31, 2017

Pubmed Data : Cardiol Rev. 2018 Mar/Apr;26(2):93-98. PMID: 29419562
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Diseases : Heart Failure
Therapeutic Actions : Acupuncture
Pharmacological Actions : Cardioprotective, Vasodilator Agents
Additional Keywords : Acupuncture, Cardioprotective, Heart Failure, Vasodilator Agents
[+]

[Cardio-renal-axis--physiology, pathophysiology, and clinical relevance?].Apr 30, 2002

Pubmed Data : Anasthesiol Intensivmed Notfallmed Schmerzther. 2002 May ;37(5):250-7. PMID: 12015681
Article Published Date : Apr 30, 2002
Study Type : Commentary
Additional Links
Diseases : Heart Failure
Additional Keywords : Cardio-renal Axis

Copyright: eraxion / 123RF Stock Photo

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