Hepatitis: Lectin-Induced (concanavalin)

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28 Substances Researched for Hepatitis: Lectin-Induced (concanavalin)
NameACCKFocus
Arctigenin24Locked
Berberine24Locked
Curcumin24Locked
Horse Chestnut24Locked
Glycyrrhizin23Locked
Alpha-Lipoic Acid12Locked
Amygdalin (laetrile)12Locked
Celastrol12Locked
Cucurbitacin E 12Locked
Dandelion 12Locked
Flavonoids12Locked
Formononetin12Locked
Fucoidan12Locked
Gastrodin12Locked
Lactoferrin12Locked
Maca12Locked
Magnolol12Locked
Paeoniflorin12Locked
Pterostilbene12Locked
Quercetin12Locked
Sweet Potato: Purple12Locked
Syringic Acid12Locked
Thymoquinone12Locked
Vanillic Acid12Locked
Xanthones12Locked
Allicin11Locked
Bee Propolis11Locked
Prunella vulgaris11Locked
1 Problem Substances Researched for Hepatitis: Lectin-Induced (concanavalin)
NameACCKFocus
Concanavalin A1935Locked

View the Evidence:
31 Abstracts with Hepatitis: Lectin-Induced (concanavalin) Research

[+]

Alpha-lipoic acid markedly attenuated Con A-induced hepatitis by modulating cytokine secretion and reducing reactive oxygen species generation.Mar 24, 2016

Pubmed Data : Int Immunopharmacol. 2016 Mar 25 ;35:53-60. Epub 2016 Mar 25. PMID: 27018751
Article Published Date : Mar 24, 2016
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Hepatitis: Lectin-Induced (concanavalin), Lipid Peroxidation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Superoxide Dismutase Up-regulation
Problem Substances : Concanavalin A
[+]

Alpha-mangostin as a new therapeutic candidate for concanavalin A-induced autoimmune hepatitis.Sep 18, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2022 Sep 19 ;11(18). Epub 2022 Sep 19. PMID: 36145841
Article Published Date : Sep 18, 2022
Study Type : Animal Study
Additional Links
Substances : Xanthones
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Hepatoprotective
[+]

Amygdalin (Vitamin B17) pretreatment attenuates experimentally induced acute autoimmune hepatitis.May 14, 2019

Pubmed Data : Ann Anat. 2019 May 15 ;224:124-132. Epub 2019 May 15. PMID: 31100343
Article Published Date : May 14, 2019
Study Type : Animal Study
Additional Links
Substances : Amygdalin (laetrile)
Diseases : Hepatitis: Autoimmune , Hepatitis: Lectin-Induced (concanavalin), Liver Damage
Pharmacological Actions : Hepatoprotective, Immunomodulatory
Problem Substances : Concanavalin A
[+]

Arctigenin could be a powerful drug candidate for acute hepatitis through immune suppression.Mar 22, 2018

Pubmed Data : Biomed Pharmacother. 2018 Mar 23 ;102:464-471. Epub 2018 Mar 23. PMID: 29579707
Article Published Date : Mar 22, 2018
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Hepatitis, Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Immunosuppressive Agents
[+]

Arctigenin might exert great therapeutic potential in immune-mediated liver injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2018 ;9:1881. Epub 2018 Aug 16. PMID: 30177931
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Apoptotic, Autophagy Inhibitors, Hepatoprotective
Problem Substances : Concanavalin A
[+]

Berbamine and thymoquinone exert protective effects against immune-mediated liver injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2022 ;9:960981. Epub 2022 Jul 26. PMID: 35958317
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Berberine, Thymoquinone
Diseases : Hepatitis: Lectin-Induced (concanavalin), Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Concanavalin A
[+]

Berberine alleviates concanavalin A-induced autoimmune hepatitis.Mar 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hepatol Commun. 2024 Apr 1 ;8(4). Epub 2024 Mar 11. PMID: 38466881
Article Published Date : Mar 31, 2024
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Hepatitis: Lectin-Induced (concanavalin), Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective
Problem Substances : Concanavalin A
[+]

Celastrol may exhibit immune regulatory effects by regulating IL-6/STAT3-IL-17 signaling in ConA-induced hepatitis.Apr 30, 2023

Pubmed Data : J Gastroenterol Hepatol. 2023 May ;38(5):821-829. Epub 2023 Mar 26. PMID: 36967570
Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Celastrol
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
Problem Substances : Concanavalin A
[+]

Cucurbitacin E glucoside alleviates concanavalin A-induced hepatitis.Jun 27, 2022

Pubmed Data : J Ethnopharmacol. 2022 Jun 28 ;292:115223. Epub 2022 Mar 27. PMID: 35354089
Article Published Date : Jun 27, 2022
Study Type : Animal Study
Additional Links
Substances : Cucurbitacin E
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation, SIRT1 Activator
Problem Substances : Concanavalin A
[+]

Curcumin attenuates Concanavalin A-induced liver injury in mice. Dec 31, 2011

Pubmed Data : Int Immunopharmacol. 2012 Jan ;12(1):151-7. Epub 2011 Dec 2. PMID: 22138522
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemically-Induced Liver Damage, Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

Curcumin inhibits HMGB1 releasing and attenuates concanavalin A-induced hepatitis in mice.Oct 10, 2012

Pubmed Data : Eur J Pharmacol. 2012 Oct 11. Epub 2012 Oct 11. PMID: 23063543
Article Published Date : Oct 10, 2012
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, High-mobility group box-1 (HMGB1) inhibitor
[+]

Escin shows extended antioxidant, anti-inflammatory, antinecrotic, and anti-apoptotic effects against Con A-induced immune-mediated hepatitis.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Inflammopharmacology. 2022 Dec ;30(6):2317-2329. Epub 2022 Sep 5. PMID: 36063304
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Horse Chestnut
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A
[+]

Formononetin could be a promising agent for the treatment of autoimmune hepatitis.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Cell Biol. 2021 Apr ;99(2):231-240. Epub 2021 Mar 22. PMID: 33749318
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Gastrodin ameliorates Concanavalin A-induced acute hepatitis.Jul 25, 2022

Pubmed Data : Immunopharmacol Immunotoxicol. 2022 Jul 26:1-10. Epub 2022 Jul 26. PMID: 35881007
Article Published Date : Jul 25, 2022
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A
[+]

Glycyrrhizin alleviates Con A-induced hepatitis.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Feb ;110:692-699. Epub 2018 Dec 12. PMID: 30553196
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Glycyrrhizin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-17 downregulation, Interleukin-6 Downregulation
Problem Substances : Concanavalin A
[+]

Hepatoprotective effect of syringic acid and vanillic acid on concanavalin a-induced liver injury.Jun 30, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2009 Jul ;32(7):1215-9. PMID: 19571388
Article Published Date : Jun 30, 2009
Study Type : Animal Study
Additional Links
Substances : Syringic Acid, Vanillic Acid
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

Horse chestnut extract could significantly protect the concanavalin A-induced acute liver injury.Jul 22, 2019

Pubmed Data : Pharmacology. 2019 Jul 23:1-11. Epub 2019 Jul 23. PMID: 31336368
Article Published Date : Jul 22, 2019
Study Type : Animal Study
Additional Links
Substances : Horse Chestnut
Diseases : Hepatitis: Lectin-Induced (concanavalin), Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A
[+]

Lactoferrin protects against concanavalin A-induced liver injury.Mar 31, 2010

Pubmed Data : Liver Int. 2010 Apr ;30(4):623-32. Epub 2010 Jan 29. PMID: 20136718
Article Published Date : Mar 31, 2010
Study Type : Animal Study
Additional Links
Substances : Lactoferrin
Diseases : Chemically-Induced Liver Damage, Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Hepatoprotective
Problem Substances : Concanavalin A
[+]

Magnolol attenuates concanavalin A-induced hepatic fibrosis.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Basic Clin Pharmacol Toxicol. 2017 Jun ;120(6):560-570. Epub 2017 Mar 7. PMID: 28032440
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Magnolol
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Paeoniflorin protects against concanavalin A-induced hepatitis.Dec 31, 2014

Pubmed Data : Int Immunopharmacol. 2015 Jan ;24(1):42-9. Epub 2014 Nov 20. PMID: 25479726
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A
[+]

Pretreatment with fucoidan from fucus vesiculosus protected against ConA-induced acute liver injury.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(4):e0152570. Epub 2016 Apr 1. PMID: 27035150
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Hepatitis: Lectin-Induced (concanavalin), Liver Damage
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
Additional Keywords : Plant Extracts
Problem Substances : Concanavalin A
[+]

Protective effect of galangin in Concanavalin A-induced hepatitis in mice.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2015 ;9:2983-92. Epub 2015 Jun 10. PMID: 26089647
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-12 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of pterostilbene on concanavalin A-induced acute liver injury.Oct 31, 2019

Pubmed Data : Food Funct. 2019 Nov 1 ;10(11):7308-7314. Epub 2019 Oct 18. PMID: 31626263
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Problem Substances : Concanavalin A
[+]

Purple sweet potato polysaccharide ameliorates concanavalin A-induced hepatic injury by inhibiting inflammation and oxidative stress.Jun 30, 2024

Pubmed Data : Phytomedicine. 2024 Jul ;129:155652. Epub 2024 Apr 17. PMID: 38663118
Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Sweet Potato: Purple
Diseases : Hepatitis: Lectin-Induced (concanavalin), Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

Taraxasterol mitigates Con A-induced hepatitis in mice by suppressing interleukin-2 expression and its signaling in T lymphocytes.Nov 26, 2021

Pubmed Data : Int Immunopharmacol. 2021 Nov 27:108380. Epub 2021 Nov 27. PMID: 34848154
Article Published Date : Nov 26, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, NF-kappaB Inhibitor
[+]

These results demonstrate that quercetin protects against ConA-mediated hepatitis in mice.Aug 12, 2015

Pubmed Data : Inflammation. 2015 Aug 13. Epub 2015 Aug 13. PMID: 26267064
Article Published Date : Aug 12, 2015
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Hepatoprotective, MicroRNA modulator
Problem Substances : Concanavalin A
[+]

This present research explores Maca as an effective hepatoprotective medicine to inhibit inflammation and liver injury caused by acute hepatitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2018 ;2018:8982756. Epub 2018 Dec 16. PMID: 30647537
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Maca
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-6 Downregulation, NF-kappaB Inhibitor, STAT3 Inhibitor
[+]

Bioassay-guided isolation of an abetiane-type diterpenoid from Prunella vulgaris That protects against concanavalin A-induced autoimmune hepatitis.Jan 26, 2021

Pubmed Data : J Nat Prod. 2021 08 27 ;84(8):2189-2199. Epub 2021 Aug 12. PMID: 34383500
Article Published Date : Jan 26, 2021
Study Type : In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Autoimmune Diseases, Hepatitis, Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Problem Substances : Concanavalin A
[+]

Glycyrrhizin attenuates renal inflammation in a mouse Con A-hepatitis model.Nov 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ren Fail. 2024 Dec ;46(1):2356023. Epub 2024 May 24. PMID: 38785317
Article Published Date : Nov 30, 2024
Study Type : In Vitro Study
Additional Links
Substances : Glycyrrhizin
Diseases : Hepatitis, Hepatitis: Lectin-Induced (concanavalin), Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation
[+]

Propolis alleviates concanavalin A-induced hepatitis by modulating cytokine secretion and inhibition of reactive oxygen species.Oct 31, 2017

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2017 Nov ;390(11):1105-1115. Epub 2017 Jul 31. PMID: 28761978
Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Bee Propolis
Diseases : Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A
[+]

This study demonstrates that immune-mediated liver damage in mice can be prevented by allicin.May 31, 2005

Pubmed Data : Liver Int. 2005 Jun ;25(3):613-21. PMID: 15910499
Article Published Date : May 31, 2005
Study Type : In Vitro Study
Additional Links
Substances : Allicin
Diseases : Hepatitis, Hepatitis: Lectin-Induced (concanavalin), Oxidative Stress
Pharmacological Actions : Antioxidants, Immunomodulatory, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Concanavalin A

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