Herbicide Toxicity

Name	AC	CK
Curcumin	2	4
Apigenin	1	2
Catechin	1	2
Ginsenosides	1	2
Melatonin	1	2
Panax Notoginseng	1	2
Thymoquinone	1	2
Chokeberry	1	1

Name	AC	CK
Paraquat	14	49
Glyphosate	3	21
Herbicides	1	5
Herbicide	2	3
Roundup (herbicide)	1	2

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Effect of occupational exposure to herbicides on oxidative stress in sprayers.Feb 28, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Saf Health Work. 2021 Mar ;12(1):127-132. Epub 2020 Oct 3. PMID: 33732538

Article Published Date : Feb 28, 2021

Study Type : Human Study

Additional Links

Diseases : Herbicide Toxicity, Oxidative Stress

Problem Substances : Glyphosate, Paraquat

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Effects of acute paraquat poisoning on cognitive ability in humans.Nov 19, 2020

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Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2020 Nov 20 ;38(11):831-834. PMID: 33287476

Article Published Date : Nov 19, 2020

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Herbicide Toxicity

Problem Substances : Paraquat

Adverse Pharmacological Actions : Neurotoxic

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The current study reports higher urinary herbicide levels among sugarcane farmers in Warunagama and Rahathangama.Mar 21, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2021 Mar 22 ;18(6). Epub 2021 Mar 22. PMID: 33810013

Article Published Date : Mar 21, 2021

Study Type : Human Study

Additional Links

Diseases : Herbicide Toxicity, Kidney Damage: Chemically-Induced

Problem Substances : Glyphosate, Paraquat

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Several widely used triazines enhance the production of toxic, aggregation prone Aβ42/Aβ43 amyloids.Oct 17, 2016

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Pubmed Data : J Alzheimers Dis. 2016 Oct 18 ;54(4):1593-1605. PMID: 27589520

Article Published Date : Oct 17, 2016

Study Type : Human In Vitro

Additional Links

Diseases : Alzheimer's Disease, Herbicide Toxicity

Additional Keywords : Increased Risk

Problem Substances : Herbicides

Adverse Pharmacological Actions : Neurotoxic

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Apigenin reduces paraquat induced acute lung injury by inhibition of inflammation and oxidative stress.Jan 18, 2016

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Pubmed Data : Inflammation. 2016 Jan 19. Epub 2016 Jan 19. PMID: 26782361

Article Published Date : Jan 18, 2016

Study Type : Animal Study

Additional Links

Substances : Apigenin

Diseases : Herbicide Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor

Additional Keywords : Dose Response

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Curcumin significantly reduced inflammatory responses and pathological changes in lung tissue exposed to paraquat.Aug 31, 2015

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Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2015 Sep ;33(9):689-92. PMID: 26832707

Article Published Date : Aug 31, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Herbicide Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

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EGCG has neuroprotective properties against paraquat-induced toxicity.Jan 01, 2008

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Pubmed Data : Cell Biol Int. 2008 Jan;32(1):22-30. Epub 2007 Sep 1. PMID: 17936647

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : Catechin

Diseases : Herbicide Toxicity

Pharmacological Actions : Apoptotic, Neuroprotective Agents

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Hemodynamic and electromechanical effects of paraquat in rat heart.Dec 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2021 ;16(4):e0234591. Epub 2021 Apr 1. PMID: 33793552

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Diseases : Herbicide Toxicity

Problem Substances : Paraquat

Adverse Pharmacological Actions : Cardiotoxic

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Immediate and late systemic and lung effects of inhaled paraquat in rats.Mar 11, 2021

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Pubmed Data : J Hazard Mater. 2021 Mar 12 ;415:125633. Epub 2021 Mar 12. PMID: 33743382

Article Published Date : Mar 11, 2021

Study Type : Animal Study

Additional Links

Diseases : Herbicide Toxicity, Lung Inflammation, Lung Injury: Acute

Problem Substances : Paraquat

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Intranasal curcumin alleviate paraquat induced pulmonary damage and pro-inflammatory cytokine levels like tumor necrosis factor-α (TNF-α) and nitric oxide (NO).Oct 31, 2014

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Pubmed Data : Environ Toxicol Pharmacol. 2014 Nov ;38(3):913-21. Epub 2014 Oct 18. PMID: 25461551

Article Published Date : Oct 31, 2014

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Herbicide Toxicity, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Paraquat administration reduces the female fertility by impairing the nuclear and cytoplasmic maturation of oocytes in mice.Dec 31, 2019

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Pubmed Data : Front Cell Dev Biol. 2020 ;8:631104. Epub 2021 Feb 2. PMID: 33634108

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Diseases : Herbicide Toxicity, Infertility: Female

Problem Substances : Paraquat

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Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans.Jan 14, 2021

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Pubmed Data : Toxicology. 2021 01 15 ;447:152632. Epub 2020 Nov 13. PMID: 33197508

Article Published Date : Jan 14, 2021

Study Type : Animal Study

Additional Links

Diseases : Herbicide Toxicity, Infertility

Additional Keywords : Transgenerational inheritance

Problem Substances : Paraquat

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Paraquat induces pulmonary fibrosis through Wnt/β-catenin signaling pathway and myofibroblast differentiation.Oct 14, 2020

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Pubmed Data : Toxicol Lett. 2020 Oct 15 ;333:170-183. Epub 2020 Aug 11. PMID: 32795487

Article Published Date : Oct 14, 2020

Study Type : Animal Study

Additional Links

Diseases : Herbicide Toxicity, Pulmonary Fibrosis

Problem Substances : Paraquat

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Paraquat treatment compromises the clearance of β-amyloid and tau proteins and induces primary hippocampal neuronal cell death.Nov 05, 2020

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Pubmed Data : Chem Res Toxicol. 2020 Nov 6. Epub 2020 Nov 6. PMID: 33156613

Article Published Date : Nov 05, 2020

Study Type : Animal Study

Additional Links

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Herbicide Toxicity

Problem Substances : Paraquat

Adverse Pharmacological Actions : Neurotoxic

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Paraquat-activated BV-2 microglia induces neuroinflammatory responses in the neuron model through NF-κB signaling pathway.Mar 31, 2021

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Pubmed Data : Toxicol In Vitro. 2021 Apr ;72:105076. Epub 2021 Jan 4. PMID: 33412245

Article Published Date : Mar 31, 2021

Study Type : Animal Study

Additional Links

Diseases : Brain Inflammation , Herbicide Toxicity

Problem Substances : Paraquat

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Protective role of thymoquinone against paraquat-induced hepatotoxicity in mice.May 31, 2018

Click here to read the entire abstract

Pubmed Data : Pestic Biochem Physiol. 2018 Jun ;148:16-21. Epub 2018 Mar 13. PMID: 29891368

Article Published Date : May 31, 2018

Study Type : Animal Study

Additional Links

Substances : Thymoquinone

Diseases : Herbicide Toxicity

Pharmacological Actions : Antioxidants, Hepatoprotective

Problem Substances : Paraquat

[+]

Saponins extracted from Panax notoginseng protect against herbicide induced neurotoxicity.Feb 03, 2010

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Pubmed Data : J Ethnopharmacol. 2010 Feb 3;127(2):419-23. Epub 2009 Oct 24. PMID: 19857566

Article Published Date : Feb 03, 2010

Study Type : Animal Study

Additional Links

Substances : Ginsenosides, Panax Notoginseng

Diseases : Herbicide Toxicity, Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Plant Extracts

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These results reveal that melatonin is a protective agent against experimentally induced maternal and embryo toxicity from herbicides.Mar 31, 2017

Click here to read the entire abstract

Pubmed Data : Acta Histochem. 2017 Apr ;119(3):220-227. Epub 2017 Feb 13. PMID: 28202179

Article Published Date : Mar 31, 2017

Study Type : Animal Study

Additional Links

Substances : Melatonin

Diseases : Herbicide Toxicity

Pharmacological Actions : Cytoprotective, Hepatoprotective

Problem Substances : Herbicide, Roundup (herbicide)

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The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis.Dec 31, 2020

Click here to read the entire abstract

Pubmed Data : Crit Rev Toxicol. 2021 Jan ;51(1):36-64. Epub 2021 Feb 2. PMID: 33528289

Article Published Date : Dec 31, 2020

Study Type : Review

Additional Links

Diseases : Herbicide Toxicity, Lung Injury: Acute, Pulmonary Fibrosis

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Aronia berry concentrate at low doses restores the homeostatic redox environment of neurons treated with paraquat.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:5296271. Epub 2015 Dec 6. PMID: 26770655

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Chokeberry

Diseases : Herbicide Toxicity

Pharmacological Actions : Antioxidants, Neuroprotective Agents

Problem Substances : Herbicide, Paraquat

[+]

Progress in the study of pulmonary fibrosis signaling pathways caused by paraquat poisoning.Feb 28, 2021

Click here to read the entire abstract

Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2021 Mar ;33(3):377-380. PMID: 33834986

Article Published Date : Feb 28, 2021

Study Type : Review

Additional Links

Diseases : Herbicide Toxicity, Pulmonary Fibrosis

Problem Substances : Paraquat

[+]

Sublethal paraquat confers multidrug tolerance in Pseudomonas aeruginosa.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Microbiol. 2020 ;11:576708. Epub 2020 Sep 25. PMID: 33101252

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Diseases : Herbicide Toxicity, Pseudomonas aeruginosa

Additional Keywords : Increased Risk

Problem Substances : Paraquat

[+]

This review reveals a coherent body of evidence indicating that GlyBH could be toxic below the regulatory lowest observed adverse effect level for chronic toxic effects.Aug 13, 2015

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2015 Aug 14. Epub 2015 Aug 14. PMID: 26282372

Article Published Date : Aug 13, 2015

Study Type : Review

Additional Links

Diseases : Herbicide Toxicity

Problem Substances : Glyphosate

Adverse Pharmacological Actions : Endocrine Disruptor

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View the Evidence: 23 Abstracts with Herbicide Toxicity Research

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Effect of occupational exposure to herbicides on oxidative stress in sprayers.Feb 28, 2021

Effects of acute paraquat poisoning on cognitive ability in humans.Nov 19, 2020

The current study reports higher urinary herbicide levels among sugarcane farmers in Warunagama and Rahathangama.Mar 21, 2021

Several widely used triazines enhance the production of toxic, aggregation prone Aβ42/Aβ43 amyloids.Oct 17, 2016

Apigenin reduces paraquat induced acute lung injury by inhibition of inflammation and oxidative stress.Jan 18, 2016

Curcumin significantly reduced inflammatory responses and pathological changes in lung tissue exposed to paraquat.Aug 31, 2015

EGCG has neuroprotective properties against paraquat-induced toxicity.Jan 01, 2008

Hemodynamic and electromechanical effects of paraquat in rat heart.Dec 31, 2020

Immediate and late systemic and lung effects of inhaled paraquat in rats.Mar 11, 2021

Intranasal curcumin alleviate paraquat induced pulmonary damage and pro-inflammatory cytokine levels like tumor necrosis factor-α (TNF-α) and nitric oxide (NO).Oct 31, 2014

Paraquat administration reduces the female fertility by impairing the nuclear and cytoplasmic maturation of oocytes in mice.Dec 31, 2019

Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans.Jan 14, 2021

Paraquat induces pulmonary fibrosis through Wnt/β-catenin signaling pathway and myofibroblast differentiation.Oct 14, 2020

Paraquat treatment compromises the clearance of β-amyloid and tau proteins and induces primary hippocampal neuronal cell death.Nov 05, 2020

Paraquat-activated BV-2 microglia induces neuroinflammatory responses in the neuron model through NF-κB signaling pathway.Mar 31, 2021

Protective role of thymoquinone against paraquat-induced hepatotoxicity in mice.May 31, 2018

Saponins extracted from Panax notoginseng protect against herbicide induced neurotoxicity.Feb 03, 2010

These results reveal that melatonin is a protective agent against experimentally induced maternal and embryo toxicity from herbicides.Mar 31, 2017

The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis.Dec 31, 2020

Aronia berry concentrate at low doses restores the homeostatic redox environment of neurons treated with paraquat.Dec 31, 2015

Progress in the study of pulmonary fibrosis signaling pathways caused by paraquat poisoning.Feb 28, 2021

Sublethal paraquat confers multidrug tolerance in Pseudomonas aeruginosa.Dec 31, 2019

This review reveals a coherent body of evidence indicating that GlyBH could be toxic below the regulatory lowest observed adverse effect level for chronic toxic effects.Aug 13, 2015

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Herbicide Toxicity

View the Evidence:
23 Abstracts with Herbicide Toxicity Research